dynorphin (1-8) has been researched along with u-50488 in 6 studies
| Studies (dynorphin (1-8)) | Trials (dynorphin (1-8)) | Recent Studies (post-2010) (dynorphin (1-8)) | Studies (u-50488) | Trials (u-50488) | Recent Studies (post-2010) (u-50488) |
|---|---|---|---|---|---|
| 173 | 0 | 3 | 1,664 | 3 | 209 |
| Protein | Taxonomy | dynorphin (1-8) (IC50) | u-50488 (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 2.15 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0027 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 2.15 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.7171 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0958 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0537 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lookingland, KJ; Manzanares, J; Moore, KE; Wagner, EJ | 1 |
| Jhamandas, K; Lemaire, S; Sutak, M | 1 |
| Bicknell, RJ; Douglas, AJ; Dye, S; Leng, G; Russell, JA | 1 |
| Hong, JS; Hudson, PM; Jin, L; Kong, LY; McMillian, MK | 1 |
| Stein, B; Teschemacher, H; Wenzlaff, H | 1 |
| Gallo, RV; Zhang, Q | 1 |
6 other study(ies) available for dynorphin (1-8) and u-50488
| Article | Year |
|---|---|
Effects of immunoneutralization of dynorphin1-17 and dynorphin1-8 on the activity of central dopaminergic neurons in the male rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 3,4-Dihydroxyphenylacetic Acid; Analgesics; Animals; Brain Chemistry; Dopamine; Dynorphins; Injections, Intraventricular; Male; Median Eminence; Neurons; Peptide Fragments; Pyrrolidines; Rats | 1992 |
Comparative spinal analgesic action of dynorphin1-8, dynorphin1-13, and a kappa-receptor agonist U50,488.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Dose-Response Relationship, Drug; Dynorphins; Injections, Spinal; Male; Morphine; Naloxone; Peptide Fragments; Pyrrolidines; Rats; Rats, Inbred Strains; Reaction Time; Spinal Cord; Time Factors | 1986 |
Endogenous opioid regulation of oxytocin secretion through pregnancy in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dynorphins; Electric Stimulation; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Male; Naloxone; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Pregnancy; Pregnancy, Animal; Protein Precursors; Pyrrolidines; Rats; Rats, Wistar; RNA, Messenger; Vasopressins | 1993 |
Inhibition of lipopolysaccharide-induced nitric oxide and cytokine production by ultralow concentrations of dynorphins in mixed glia cultures.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cells, Cultured; Dynorphins; Lipopolysaccharides; Mice; Naltrexone; Neuroglia; Nitric Oxide; Peptide Fragments; Pyrrolidines; Tumor Necrosis Factor-alpha | 1997 |
Diminution of contractile response by kappa-opioid receptor agonists in isolated rat ventricular cardiomyocytes is mediated via a pertussis toxin-sensitive G protein.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antihypertensive Agents; Cells, Cultured; Drug Interactions; Dynorphins; GTP-Binding Proteins; Heart Ventricles; Male; Myocardial Contraction; Peptide Fragments; Pertussis Toxin; Rats; Rats, Wistar; Receptors, Opioid, kappa; Virulence Factors, Bordetella | 1998 |
Effect of prodynorphin-derived opioid peptides on the ovulatory luteinizing hormone surge in the proestrous rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Brain; Dynorphins; Enkephalins; Female; Luteinizing Hormone; Naltrexone; Ovulation; Peptide Fragments; Proestrus; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa | 2002 |