dynorphin (1-8) has been researched along with naloxone in 19 studies
| Studies (dynorphin (1-8)) | Trials (dynorphin (1-8)) | Recent Studies (post-2010) (dynorphin (1-8)) | Studies (naloxone) | Trials (naloxone) | Recent Studies (post-2010) (naloxone) |
|---|---|---|---|---|---|
| 173 | 0 | 3 | 20,134 | 1,257 | 3,321 |
| Protein | Taxonomy | dynorphin (1-8) (IC50) | naloxone (IC50) |
|---|---|---|---|
| Cytochrome P450 2D6 | Homo sapiens (human) | 2 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.043 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0219 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0397 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1896 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.05 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0795 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0154 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0089 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.0055 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (47.37) | 18.7374 |
| 1990's | 8 (42.11) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dayanithi, G; Nordmann, JJ; Stuenkel, EL | 1 |
| Koehler, E; McLemore, GL; Rosella-Dampman, LM; Summy-Long, JY | 1 |
| Caffrey, JL; Carter, GC; Hathorne, LF; Sinclair, RJ | 1 |
| Bicknell, RJ; Hatton, GI; Inenaga, K; Luckman, SM; Mason, WT | 1 |
| Bryant, HU; Conroy, WG; Isom, GE; Malven, PV; Yim, GK | 1 |
| Falke, N; Martin, R | 1 |
| Jhamandas, K; Lemaire, S; Sutak, M | 1 |
| Hommer, DW; Robertson, BC; Skirboll, LR | 1 |
| McLean, S; Rothman, RB | 1 |
| Bondy, CA; Gainer, H; Russell, JT | 1 |
| Iadarola, MJ; Porter, JR; Roane, DS | 1 |
| Herz, A; Schulz, R; Wüster, M | 1 |
| Barnard, EA; Benyhe, S; Borsodi, A; Simon, J; Wollemann, M | 1 |
| Koekkoek-van den Herik, I; Maigret, C; Smelik, WF; Van de Heijning, BJ; van Wimersma Greidanus, TB | 1 |
| Meyer, ME | 1 |
| Bicknell, RJ; Douglas, AJ; Dye, S; Leng, G; Russell, JA | 1 |
| Dewey, WL; Smith, FL | 1 |
| Akahori, K; Iwao, K; Kitamura, K; Oka, T; Yano, H | 1 |
| Tiniakov, RL; Wang, L; Yeates, DB | 1 |
19 other study(ies) available for dynorphin (1-8) and naloxone
| Article | Year |
|---|---|
Intracellular calcium and hormone release from nerve endings of the neurohypophysis in the presence of opioid agonists and antagonists.
Topics: Animals; Arginine Vasopressin; Benzomorphans; Calcium; Cytoplasm; Diprenorphine; Dynorphins; Electric Stimulation; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Narcotics; Nerve Endings; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Potassium; Rats; Rats, Sprague-Dawley; Rats, Wistar | 1992 |
Kappa opiate receptors inhibit release of oxytocin from the magnocellular system during dehydration.
Topics: Animals; Benzomorphans; Dehydration; Dynorphins; Endorphins; Hypertonic Solutions; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Osmolar Concentration; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Vasopressins | 1990 |
Naloxone potentiates contractile responses to epinephrine in isolated canine arteries.
Topics: Animals; Clonidine; Corticosterone; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Dynorphins; Epinephrine; Muscle Contraction; Muscle, Smooth, Vascular; Naloxone; Norepinephrine; Peptide Fragments; Phenylephrine; Receptors, Opioid; Renal Artery | 1990 |
Beta-adrenergic and opioid receptors on pituicytes cultured from adult rat neurohypophysis: regulation of cell morphology.
Topics: Animals; Antigens, Surface; Cells, Cultured; Dynorphins; Glial Fibrillary Acidic Protein; Male; Naloxone; Peptide Fragments; Pituitary Gland, Posterior; Rats; Receptors, Adrenergic, beta; Receptors, Opioid; Thy-1 Antigens | 1989 |
Presence of dynorphin-like immunoreactivity but not opiate binding in Walker-256 tumors.
Topics: Animals; Carcinoma 256, Walker; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Hormones, Ectopic; Male; Muscles; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid | 1985 |
Opioid binding in a rat neurohypophysial fraction enriched in oxytocin and vasopressin nerve endings.
Topics: Animals; Arginine Vasopressin; Binding Sites; Diprenorphine; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Male; Naloxone; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Rats | 1985 |
Comparative spinal analgesic action of dynorphin1-8, dynorphin1-13, and a kappa-receptor agonist U50,488.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Dose-Response Relationship, Drug; Dynorphins; Injections, Spinal; Male; Morphine; Naloxone; Peptide Fragments; Pyrrolidines; Rats; Rats, Inbred Strains; Reaction Time; Spinal Cord; Time Factors | 1986 |
Electrophysiological evidence for a non-opioid interaction between dynorphin and GABA in the substantia nigra of the rat.
Topics: Action Potentials; Animals; Benzomorphans; Drug Interactions; Dynorphins; gamma-Aminobutyric Acid; Injections, Intravenous; Male; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Chloride; Substantia Nigra | 1987 |
An examination of the opiate receptor subtypes labeled by [3H]cycloFOXY: an opiate antagonist suitable for positron emission tomography.
Topics: Animals; Autoradiography; Brain; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Naloxone; Naltrexone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Synaptic Membranes; Tomography, Emission-Computed | 1988 |
Dynorphin A inhibits and naloxone increases the electrically stimulated release of oxytocin but not vasopressin from the terminals of the neural lobe.
Topics: Animals; Dynorphins; Electric Stimulation; Male; Models, Biological; Naloxone; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Vasopressins | 1988 |
Decreased [3H]-naloxone binding and elevated dynorphin-A(1-8) content in Zucker rat brain.
Topics: Animals; Body Weight; Brain; Dynorphins; Female; Hypothalamic Area, Lateral; Hypothalamus, Middle; Naloxone; Peptide Fragments; Periaqueductal Gray; Radioligand Assay; Rats; Rats, Zucker; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1988 |
Receptor preference of dynorphin A fragments in the mouse vas deferens determined by different techniques.
Topics: Animals; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Male; Mice; Naloxone; Naltrexone; Peptide Fragments; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens | 1984 |
[3H]dynorphin1-8 binding sites in frog (Rana esculenta) brain membranes.
Topics: Amino Acid Sequence; Animals; Brain; Cell Membrane; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Guanylyl Imidodiphosphate; Molecular Sequence Data; Naloxone; Peptide Fragments; Rana esculenta; Receptors, Opioid; Sodium Chloride; Tritium | 1994 |
Dynorphin-A and vasopressin release in the rat: a structure-activity study.
Topics: Analysis of Variance; Animals; Arginine Vasopressin; Cerebral Ventricles; Dynorphins; Immune Sera; In Vitro Techniques; Injections, Intraventricular; Male; Naloxone; Peptide Fragments; Pituitary Gland, Posterior; Radioimmunoassay; Rats; Rats, Wistar; Structure-Activity Relationship; Time Factors | 1994 |
Intrastriatal injections of dynorphin A fragments potentiate the dorsal immobility response in rats.
Topics: Amino Acid Sequence; Animals; Corpus Striatum; Dynorphins; Male; Microinjections; Molecular Sequence Data; Motor Activity; Naloxone; Peptide Fragments; Rats; Stereotyped Behavior | 1993 |
Endogenous opioid regulation of oxytocin secretion through pregnancy in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dynorphins; Electric Stimulation; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Male; Naloxone; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Pregnancy; Pregnancy, Animal; Protein Precursors; Pyrrolidines; Rats; Rats, Wistar; RNA, Messenger; Vasopressins | 1993 |
Endogenous dynorphin modulates calcium-mediated antinociception in mice.
Topics: Animals; Calcium; Dynorphins; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Nociceptors; Peptide Fragments; Phenobarbital | 1993 |
Effects of peptidase inhibitors on anti-nociceptive action of dynorphin-(1-8) in rats.
Topics: Analgesics, Opioid; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Bacterial Agents; Captopril; Drug Interactions; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Glycopeptides; Injections, Intraventricular; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Peptide Fragments; Peptides; Protease Inhibitors; Rats; Rats, Wistar; Receptors, Opioid, mu | 2000 |
Peripheral opioidergic regulation of the tracheobronchial mucociliary transport system.
Topics: Aerosols; Animals; beta-Endorphin; Bronchi; Dogs; Drug Synergism; Dynorphins; Enkephalin, Leucine-2-Alanine; In Vitro Techniques; Injections, Intramuscular; Ions; Male; Mucociliary Clearance; Naloxone; Narcotic Antagonists; Peptide Fragments; Sheep; Trachea; Water | 2003 |