Compounds > dynorphin (1-8)
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dynorphin (1-8) and gamma-aminobutyric acid

dynorphin (1-8) has been researched along with gamma-aminobutyric acid in 5 studies

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

Compound Research Comparison

Studies
(dynorphin (1-8))		Trials
(dynorphin (1-8))		Recent Studies (post-2010)
(dynorphin (1-8))		Studies
(gamma-aminobutyric acid)		Trials
(gamma-aminobutyric acid)		Recent Studies (post-2010) (gamma-aminobutyric acid)
1730340,2151,4239,631

Protein Interaction Comparison

ProteinTaxonomydynorphin (1-8) (IC50)gamma-aminobutyric acid (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid type B receptor subunit 2Rattus norvegicus (Norway rat)0.0292
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.0332
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.0323
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)2.152
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.0333
Sodium- and chloride-dependent GABA transporter 1Homo sapiens (human)5.2623
Sodium- and chloride-dependent taurine transporterHomo sapiens (human)354
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)2.51
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.02
Sodium- and chloride-dependent GABA transporter 1Mus musculus (house mouse)6.349
Sodium- and chloride-dependent GABA transporter 2Mus musculus (house mouse)7.0795
Sodium- and chloride-dependent GABA transporter 3Mus musculus (house mouse)8.1283
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.02
Sodium- and chloride-dependent betaine transporterHomo sapiens (human)6.4082
Sodium- and chloride-dependent GABA transporter 3Homo sapiens (human)3.9953
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.0333
GABA theta subunitRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid type B receptor subunit 1Rattus norvegicus (Norway rat)0.0292

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Faden, AI1
Barnes, MI; Hong, JS; Hudson, PM; Mitchell, CL1
Moises, HC; Walker, JM1
Grimes, L; Hong, JS; Hudson, PM; Mitchell, CL1
Hommer, DW; Robertson, BC; Skirboll, LR1

Other Studies

5 other study(ies) available for dynorphin (1-8) and gamma-aminobutyric acid

ArticleYear
Dynorphin increases extracellular levels of excitatory amino acids in the brain through a non-opioid mechanism.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1992, Volume: 12, Issue:2

    Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Dialysis; Dynorphins; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine; Kinetics; Male; Neurotransmitter Agents; Peptide Fragments; Rats; Rats, Inbred Strains; Serine; Stereotaxic Techniques; Taurine; Threonine

1992
Opioid mu and delta receptor antagonists reduce wet dog shaking elicited by perforant path stimulation.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:4

    Topics: Animals; Dynorphins; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Methionine; gamma-Aminobutyric Acid; Hippocampus; Male; Naltrexone; Peptide Fragments; Rats; Rats, Inbred F344; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereotyped Behavior

1991
Electrophysiological effects of dynorphin peptides on hippocampal pyramidal cells in rat.
    European journal of pharmacology, 1985, Jan-15, Volume: 108, Issue:1

    Topics: Animals; Cyclazocine; Dynorphins; Electrophysiology; Endorphins; Enkephalin, Leucine; Ethylketocyclazocine; gamma-Aminobutyric Acid; Hippocampus; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid

1985
Stimulation of the perforant path alters hippocampal levels of opioid peptides, glutamine and GABA.
    Brain research, 1987, Dec-01, Volume: 435, Issue:1-2

    Topics: Amino Acids; Animals; Dynorphins; Electric Stimulation; Enkephalin, Methionine; gamma-Aminobutyric Acid; Glutamine; Hippocampus; Male; Peptide Fragments; Rats; Rats, Inbred F344; Stereotyped Behavior

1987
Electrophysiological evidence for a non-opioid interaction between dynorphin and GABA in the substantia nigra of the rat.
    Neuroscience, 1987, Volume: 23, Issue:2

    Topics: Action Potentials; Animals; Benzomorphans; Drug Interactions; Dynorphins; gamma-Aminobutyric Acid; Injections, Intravenous; Male; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Chloride; Substantia Nigra

1987