dynorphin (1-8) has been researched along with dynorphins in 162 studies
| Studies (dynorphin (1-8)) | Trials (dynorphin (1-8)) | Recent Studies (post-2010) (dynorphin (1-8)) | Studies (dynorphins) | Trials (dynorphins) | Recent Studies (post-2010) (dynorphins) |
|---|---|---|---|---|---|
| 173 | 0 | 3 | 3,096 | 24 | 514 |
| 173 | 0 | 3 | 368 | 4 | 15 |
| Protein | Taxonomy | dynorphin (1-8) (IC50) | dynorphins (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.0077 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0001 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 86 (53.09) | 18.7374 |
| 1990's | 60 (37.04) | 18.2507 |
| 2000's | 13 (8.02) | 29.6817 |
| 2010's | 2 (1.23) | 24.3611 |
| 2020's | 1 (0.62) | 2.80 |
| Authors | Studies |
|---|---|
| Faden, AI | 1 |
| Ingenito, AJ; Wang, JQ | 4 |
| Lookingland, KJ; Manzanares, J; Moore, KE; Wagner, EJ | 2 |
| Dayanithi, G; Nordmann, JJ; Stuenkel, EL | 1 |
| Humphrey, E; Hylden, JLK; Nahin, RL | 1 |
| Berrettini, W; Gold, PW; Hamburger, S; Kruesi, MJ; Leonard, HL; Listwak, SJ; Potter, WZ; Rettew, DC; Stipetic, M; Swedo, SE | 1 |
| Berrettini, WH; Jimerson, DC; Kaye, WH; Lesem, MD | 1 |
| Barnes, MI; Hong, JS; Hudson, PM; Mitchell, CL | 1 |
| Ballenger, JC; Brady, KT; Fossey, M; Laraia, M; Lydiard, RB; Shook, J | 1 |
| Baronti, F; Berrettini, WH; Brughitta, G; Chase, TN; Conant, KE; Davis, TL; Giuffra, M; Iadarola, MJ; Mouradian, MM | 1 |
| Hong, JS; Lee, PH; McGinty, JF; Mitchell, CL; Xie, CW | 1 |
| Chung, K; Coggeshall, RE; Klein, CM; Sorkin, LS | 1 |
| Gallagher, M; Hong, JS; Hudson, PM; Mundy, WR; Thai, L; Tilson, HA; Zhang, WQ | 1 |
| Benoliel, JJ; Besson, JM; Bourgoin, S; Carayon, A; Cesselin, F; Hamon, M; Lombard, MC; Mauborgne, A; Pohl, M; Taquet, H | 1 |
| Gershon, MD; Kirchgessner, AL; Mawe, GM | 1 |
| Iadarola, MJ; Kleinman, JE; Ofri, D | 1 |
| Berrettini, WH; Cohen, RM; Lawlor, BA; Martinez, RA; Molchan, SE; Sunderland, T; Tariot, PN; Vitiello, B | 1 |
| Arakawa, Y; Araki, S; Ikeda, M; Kaneko, T; Matsunaga, M; Nakazawa, T; Tachibana, S; Tsuchiya, Y; Yamatsu, K; Yoshino, H | 1 |
| Fiorica-Howells, E; Spector, S | 1 |
| Dixon, DM; Traynor, JR | 3 |
| Hong, JS; Mitchell, CL; Xie, CW | 1 |
| Bak, TH; Carr, KD | 1 |
| Arakawa, Y; Kaneko, T; Nakazawa, T; Tachibana, S; Yamatsu, K; Yoshino, H | 1 |
| Koehler, E; McLemore, GL; Rosella-Dampman, LM; Summy-Long, JY | 1 |
| Caffrey, JL; Carter, GC; Hathorne, LF; Sinclair, RJ | 1 |
| Ayala, JM; Molineaux, CJ | 1 |
| Hong, JS; Ingenito, AJ; Li, SJ | 1 |
| Nahin, RL | 1 |
| Tseng, LF | 1 |
| Anderson, GM; Berrettini, WH; Bissette, G; Chappell, P; Cohen, DJ; Goodman, WK; Hardin, M; Leckman, JF; Nemeroff, CB; Riddle, MA | 1 |
| Cliffer, KD; Elde, RP; Giesler, GJ; Urca, G | 1 |
| Agid, Y; Benoliel, JJ; Cesselin, F; Hamon, M; Javoy-Agid, F; Legrand, JC; Mauborgne, A; Taquet, H; Tramu, G | 1 |
| Clements, JA; Fullerton, MJ; Funder, JW; Smith, AI | 1 |
| Bicknell, RJ; Hatton, GI; Inenaga, K; Luckman, SM; Mason, WT | 1 |
| Ingenito, AJ; Li, SJ; Wong, SC | 1 |
| Murphy, R; Steele, PA; Turner, CA | 1 |
| Dubner, R; Hylden, JL; Iadarola, MJ; Nahin, RL | 1 |
| Baty, LT; Gannon, RL; Terrian, DM | 1 |
| Carlton, SM; Hayes, ES | 1 |
| Damron, DS; Dorman, RV; Gannon, RL; Terrian, DM | 1 |
| Gannon, RL; Terrian, DM | 1 |
| Wolter, HJ | 3 |
| Moises, HC; Walker, JM | 1 |
| Akil, H; Dores, RM; Khachaturian, H; Lewis, ME; Watson, SJ | 1 |
| Honzawa, M; Matsuo, H; Miyata, A; Mizuno, K; Tohyama, M | 1 |
| Gillan, MG; Kosterlitz, HW; McKnight, AT; Robson, LE | 2 |
| Chang, JK; Gu, NF; Potkin, S; Webber, R; Xi, GF; Xia, ZY; Yao, JL; Zhang, AZ; Zhou, GZ | 1 |
| Hong, JS; Kanamatsu, T; McGinty, JF; Mitchell, CL; Sabol, SL; Yoshikawa, K | 1 |
| Bryant, HU; Conroy, WG; Isom, GE; Malven, PV; Yim, GK | 1 |
| Zamir, N | 1 |
| Barchas, JD; Evans, CJ; Lorenz, RG | 1 |
| Falke, N; Martin, R | 1 |
| Akil, H; Dores, RM | 1 |
| Iadarola, MJ; McNamara, JO; Shin, C; Yang, HY | 1 |
| Allrich, RD; Gregg, DW; Malven, PV; Moss, GE; Parfet, JR | 1 |
| Barden, N; Gerstberger, R | 1 |
| Jhamandas, K; Lemaire, S; Sutak, M | 1 |
| Arendt, RM; Herz, A; Hornykiewicz, O; Kish, SJ; Liebisch, DC; Seizinger, BR | 1 |
| Fallon, JH; Leslie, FM | 1 |
| Kirby, GC; McQueen, DS | 1 |
| Acker, GR; Molineaux, C; Orlowski, M | 1 |
| Hong, JS; Li, S; Sivam, SP | 1 |
| Ikeda, H; Imura, H; Koh, T; Matsuo, T; Nakai, Y; Takahashi, H; Tsujii, S; Usui, T | 1 |
| Hong, JS; Lee, RJ; Lomax, P; McGinty, JF | 1 |
| Conway, EL; Louis, WJ; Maccarrone, C; Verberne, AJ | 1 |
| Ahmed, MS; Dass, C; Desiderio, DM; Fridland, G; Randall, LW; Sibai, B; Tolun, E | 1 |
| Dyer, RS; Grimes, L; Harry, GJ; Hong, JS; Peterson, NJ; Rogers, BC; Tilson, HA | 1 |
| Augood, S; Diez-Guerra, FJ; Dyer, RG; Emson, PC | 1 |
| Gaymann, W; Martin, R | 1 |
| Jiang, CH; Sun, QF; Yin, SH; Zhou, GZ | 1 |
| Goldstein, A; Xie, GX | 1 |
| Breese, GR; Hong, JS; Krause, JE; Mueller, RA; Napier, TC; Sivam, SP | 1 |
| Grimes, L; Hong, JS; Kanamatsu, T; McGinty, JF | 1 |
| Hong, JS; Sivam, SP; Smith, DR; Takeuchi, K | 1 |
| Grimes, L; Hong, JS; Hudson, PM; Mitchell, CL | 1 |
| Fullerton, MJ; Funder, JW; Smith, AI | 1 |
| Zhang, LD | 1 |
| Hommer, DW; Robertson, BC; Skirboll, LR | 1 |
| McLean, S; Rothman, RB | 1 |
| Bondy, CA; Gainer, H; Russell, JT | 1 |
| Dax, EM; Fullerton, M; Funder, JW; Reichman, C; Smith, AI; Wallace, C | 1 |
| Hill, RG; Hughes, J; Hunter, JC; Sharif, NA | 1 |
| Calvetta, L; Civelli, O; Douglass, J; Herbert, E; Hong, JS; Li, S; McGinty, JF; Sivam, SP; Takeuchi, K | 1 |
| Civelli, O; Douglass, J; Iadarola, MJ; Naranjo, JR | 1 |
| Camargo, AC; Metters, KM; Oliveira, EB; Rossier, J; Toffoletto, O | 1 |
| Iadarola, MJ; Porter, JR; Roane, DS | 1 |
| Hiranuma, T; Numata, H; Oka, T | 1 |
| Abe, J; Ibata, Y; Kitamura, T; Matsuo, H; Minamino, N; Okamura, H; Paull, WK | 1 |
| Ruda, MA; Takahashi, O; Traub, RJ | 1 |
| Brady, LS; Draisci, G; Dubner, R; Iadarola, MJ | 1 |
| Schwyzer, R | 1 |
| Barchas, JD; Cone, RI; Goldstein, A; Weber, E | 1 |
| Grimm, C; Herz, A; Höllt, V; Seizinger, BR | 1 |
| Aoki, K; Kajiwara, M; Oka, T | 1 |
| Barchas, JD; Evans, CJ; Wallace, EF; Weber, E | 1 |
| Bakhit, C; Bloom, FE; Chavkin, C; Weber, E | 1 |
| Devi, L; Goldstein, A | 1 |
| Członkowski, A; Herz, A; Millan, MH; Millan, MJ | 1 |
| Herz, A; Höllt, V; Seizinger, BR | 2 |
| Herz, A; Schulz, R; Wüster, M | 1 |
| Brownstein, MJ; Palkovits, M; Zamir, N | 1 |
| Cox, BM; Molineaux, CJ; Rosenberger, JG | 1 |
| Grimm, C; Herz, A; Liebisch, DC; Seizinger, BR | 1 |
| Faden, AI; Feuerstein, G | 1 |
| Elde, RP; Sasek, CA; Seybold, VS | 1 |
| Pilapil, C; Quirion, R | 1 |
| Cox, BM; Gainer, H; Molineaux, CJ; Whitnall, MH | 1 |
| Matsuo, H; Minamino, N; Miyata, A; Mizuno, K | 1 |
| Fukuda, A; Iagarashi, M; Kangawa, K; Matsuo, H; Minamino, N | 1 |
| Agbas, A; Ahmed, MS; Cemerikic, B; Dass, C; Desiderio, DM; Millington, W; Tseng, JL | 1 |
| Berman, Y; Carr, KD; Devi, L | 2 |
| Healy, DJ; Meador-Woodruff, JH | 1 |
| Cheng, JS; Wang, BE | 1 |
| Barnard, EA; Benyhe, S; Borsodi, A; Simon, J; Wollemann, M | 1 |
| Chen, XH; Han, JS; Yan, SC; Yuan, Y | 1 |
| Koekkoek-van den Herik, I; Maigret, C; Smelik, WF; Van de Heijning, BJ; van Wimersma Greidanus, TB | 1 |
| Meyer, ME | 1 |
| Chan, J; Pickel, VM; Sesack, SR | 1 |
| Bicknell, RJ; Douglas, AJ; Dye, S; Leng, G; Russell, JA | 1 |
| Dewey, WL; Smith, FL | 1 |
| Meador-Woodruff, JH; Ramsdell, CD | 1 |
| Cai, Y; Deng, JP; Lu, QC; Su, M; Sun, XJ; Wang, J; Zhang, Y; Zhu, H | 1 |
| Goldstein, BD; Zachariou, V | 2 |
| Hjorth, SA; Schwartz, TW; Thirstrup, K | 1 |
| Duggan, AW; Riley, RC; Zhao, ZQ | 1 |
| Hong, JS; Hudson, PM; Jin, L; Kong, LY; McMillian, MK | 1 |
| Duggan, AW; Riley, RC | 1 |
| Bell, KM; Traynor, JR | 1 |
| Arai, Y; Hiranuma, T; Iwao, K; Kanai, M; Kitamura, K; Oka, T; Taniguchi, T | 1 |
| Stein, B; Teschemacher, H; Wenzlaff, H | 1 |
| Prokai, L; Zharikova, AD | 1 |
| Butelman, ER; Kreek, MJ; Vivian, JA; Woods, JH; Yu, J | 1 |
| Anderson, GM; Chappell, PB; Goodman, WK; Leckman, JF; Riddle, MA; van Wattum, PJ | 1 |
| Cadet, JL; Emilien, B; Goodman, CB; Heyliger, S; Lee, CH; Partilla, JS; Rothman, RB; Yang, HY | 1 |
| Akahori, K; Iwao, K; Kitamura, K; Oka, T; Yano, H | 1 |
| Andoh, T; Itoh, H; Kamiya, Y; Okumura, F; Sasaki, T; Watanabe, I | 1 |
| Nie, H; Qiao, JT; Wang, H; Wang, R; Zhang, R | 1 |
| Di Toro, R; Falcucci, B; Marrazzo, A; Pasquinucci, L; Pittalà, V; Prezzavento, O; Ronsisvalle, G; Spampinato, S | 1 |
| Ballet, S; Bourgoin, S; Braz, J; Cesselin, F; Hamon, M; Mauborgne, A; Zajac, JM | 1 |
| Gallo, RV; Zhang, Q | 1 |
| Gallo, RV; McCoy, JM; Zhang, Q | 1 |
| Tiniakov, RL; Wang, L; Yeates, DB | 1 |
| Gers, T; Izdebski, J; Kunce, D; Markowski, P | 1 |
| Dafny, N; Qiao, JT; Zhang, Y | 1 |
| Bai, L; Gianoulakis, C; Lam, M; Marinelli, PW; Quirion, R | 1 |
| J White, A; Lan, J; Minami, M; Pignataro, G; Simon, RP; Steiner, DF; Xiong, Z; Yang, T; Zhan, S; Zhao, H; Zhou, A; Zhu, X | 1 |
| Bai, L; Gianoulakis, C; Jarjour, S | 1 |
| Gianoulakis, C; Lam, MP | 1 |
| Lane, DA; Mackie, K; Pickel, VM; Shobin, ET | 1 |
| Chen, M; Cheng, Y; Du, S; Fan, J; Ma, S; Qu, H; Shi, J; Sun, H; Yao, Q; Zhan, S; Zhang, M; Zhang, X | 1 |
1 review(s) available for dynorphin (1-8) and dynorphins
| Article | Year |
|---|---|
Studies of the release of immunoreactive galanin and dynorphin A(1-8) in the spinal cord of the rat.
Topics: Animals; Dynorphins; Galanin; Immunohistochemistry; Peptide Fragments; Rats; Spinal Cord | 1996 |
161 other study(ies) available for dynorphin (1-8) and dynorphins
| Article | Year |
|---|---|
Dynorphin increases extracellular levels of excitatory amino acids in the brain through a non-opioid mechanism.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Dialysis; Dynorphins; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine; Kinetics; Male; Neurotransmitter Agents; Peptide Fragments; Rats; Rats, Inbred Strains; Serine; Stereotaxic Techniques; Taurine; Threonine | 1992 |
Centrally mediated cardiovascular actions of dynorphin A(1-8) on rat hippocampal formation.
Topics: Animals; Blood Pressure; Dynorphins; Heart Rate; Hippocampus; Injections, Intraventricular; Lidocaine; Male; Naltrexone; Peptide Fragments; Rats; Rats, Inbred Strains; Respiration | 1992 |
Effects of immunoneutralization of dynorphin1-17 and dynorphin1-8 on the activity of central dopaminergic neurons in the male rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 3,4-Dihydroxyphenylacetic Acid; Analgesics; Animals; Brain Chemistry; Dopamine; Dynorphins; Injections, Intraventricular; Male; Median Eminence; Neurons; Peptide Fragments; Pyrrolidines; Rats | 1992 |
Intracellular calcium and hormone release from nerve endings of the neurohypophysis in the presence of opioid agonists and antagonists.
Topics: Animals; Arginine Vasopressin; Benzomorphans; Calcium; Cytoplasm; Diprenorphine; Dynorphins; Electric Stimulation; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Narcotics; Nerve Endings; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Potassium; Rats; Rats, Sprague-Dawley; Rats, Wistar | 1992 |
Demonstration of dynorphin A 1-8 immunoreactive axons contacting spinal cord projection neurons in a rat model of peripheral inflammation and hyperalgesia.
Topics: Animals; Axons; Dendrites; Dynorphins; Immunohistochemistry; Inflammation; Male; Nerve Endings; Neurons; Pain; Peptide Fragments; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Spinal Cord | 1992 |
Cerebrospinal fluid neurochemistry in children and adolescents with obsessive-compulsive disorder.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Arginine Vasopressin; Child; Clomipramine; Corticotropin-Releasing Hormone; Dynorphins; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Neuropeptides; Obsessive-Compulsive Disorder; Oxytocin; Peptide Fragments; Severity of Illness Index | 1992 |
Measurement of CSF dynorphin A 1-8 immunoreactivity in anorexia nervosa and normal-weight bulimia.
Topics: Adult; Anorexia Nervosa; Body Weight; Brain; Bulimia; Dynorphins; Endorphins; Female; Humans; Peptide Fragments; Psychiatric Status Rating Scales; Receptors, Opioid | 1991 |
Opioid mu and delta receptor antagonists reduce wet dog shaking elicited by perforant path stimulation.
Topics: Animals; Dynorphins; Electric Stimulation; Enkephalin, Leucine; Enkephalin, Methionine; gamma-Aminobutyric Acid; Hippocampus; Male; Naltrexone; Peptide Fragments; Rats; Rats, Inbred F344; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereotyped Behavior | 1991 |
CSF opioids in panic disorder.
Topics: Adult; Arousal; beta-Endorphin; Dynorphins; Female; Humans; Male; Panic Disorder; Peptide Fragments; Personality Inventory | 1991 |
Opioid peptides in Parkinson's disease: effects of dopamine repletion.
Topics: Adult; Aged; Aged, 80 and over; Dopamine; Dynorphins; Endorphins; Enkephalin, Methionine; Female; Homovanillic Acid; Humans; Infusions, Intravenous; Levodopa; Male; Middle Aged; Parkinson Disease; Peptide Fragments | 1991 |
A glutamate antagonist blocks perforant path stimulation-induced reduction of dynorphin peptide and prodynorphin mRNA levels in rat hippocampus.
Topics: Animals; Dipeptides; Dynorphins; Enkephalins; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Histocytochemistry; Male; Neural Pathways; Peptide Fragments; Protein Precursors; Rats; Rats, Inbred F344; RNA, Messenger; Tremor | 1991 |
Unmyelinated primary afferent fiber stimulation depletes dynorphin A (1-8) immunoreactivity in rat ventral horn.
Topics: Afferent Pathways; Analysis of Variance; Animals; Dynorphins; Electric Stimulation; Immunohistochemistry; Interneurons; Motor Activity; Motor Neurons; Nerve Fibers; Neurons; Peptide Fragments; Rats; Reference Values; Sciatic Nerve; Spinal Cord | 1991 |
Decreased glutamate release correlates with elevated dynorphin content in the hippocampus of aged rats with spatial learning deficits.
Topics: Aging; Animals; Axons; Dynorphins; Glutamates; Glutamic Acid; Hippocampus; Learning Disabilities; Male; Microdialysis; Peptide Fragments; Radioimmunoassay; Rats; Rats, Inbred F344; Spatial Behavior; Synaptic Transmission | 1991 |
Regional distribution of calcitonin gene-related peptide-, substance P-, cholecystokinin-, Met5-enkephalin-, and dynorphin A (1-8)-like materials in the spinal cord and dorsal root ganglia of adult rats: effects of dorsal rhizotomy and neonatal capsaicin.
Topics: Afferent Pathways; Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Capsaicin; Cholecystokinin; Dynorphins; Enkephalin, Methionine; Ganglia, Spinal; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Reference Values; Spinal Cord; Spinal Nerves; Substance P | 1990 |
Evaluation of the activity of chemically identified enteric neurons through the histochemical demonstration of cytochrome oxidase.
Topics: Alkaline Phosphatase; Animals; Calcitonin; Calcitonin Gene-Related Peptide; Colchicine; Densitometry; Dynorphins; Electron Transport Complex IV; Guinea Pigs; Immunohistochemistry; Intestines; Male; Myenteric Plexus; Neurons; Neuropeptide Y; Peptide Fragments; Serotonin; Staining and Labeling; Synaptic Transmission | 1990 |
Enkephalin, dynorphin and substance P in postmortem substantia nigra from normals and schizophrenic patients.
Topics: Adult; Chromatography, High Pressure Liquid; Dynorphins; Enkephalin, Methionine; Female; Humans; Male; Middle Aged; Peptide Fragments; Radioimmunoassay; Schizophrenia; Substance P; Substantia Nigra | 1991 |
Reduced cerebrospinal fluid dynorphin A1-8 in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Brain; Depressive Disorder; Dynorphins; Female; Galanin; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Mental Recall; Methoxyhydroxyphenylglycol; Middle Aged; Neuropeptide Y; Neuropsychological Tests; Peptide Fragments; Peptides; Receptors, Opioid; Vasoactive Intestinal Peptide | 1991 |
Synthesis and structure-activity relationships of dynorphin A-(1-8) amide analogues.
Topics: Amino Acid Sequence; Analgesia; Animals; Biological Assay; Dynorphins; Guinea Pigs; Male; Mice; Molecular Sequence Data; Muscle, Smooth; Peptide Fragments; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa; Structure-Activity Relationship | 1990 |
Selectivity of some "specific" opioid ligands?
Topics: Animals; Benzomorphans; Binding, Competitive; Brain; Dynorphins; Female; Haloperidol; In Vitro Techniques; Mice; Morphinans; Peptide Fragments; Phencyclidine; Piperidines; Receptors, Opioid | 1990 |
Formation of [Leu5]enkephalin from dynorphin A(1-8) by rat central nervous tissue in vitro.
Topics: Animals; Brain; Central Nervous System; Dynorphins; Endorphins; Enkephalin, Leucine; In Vitro Techniques; Male; Peptide Fragments; Protease Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord | 1990 |
Perforant path stimulation differentially alters prodynorphin mRNA and proenkephalin mRNA levels in the entorhinal cortex-hippocampal region.
Topics: Animals; Cerebral Cortex; Dynorphins; Electric Stimulation; Enkephalins; Gene Expression Regulation; Hippocampus; Male; Nucleic Acid Hybridization; Peptide Fragments; Protein Precursors; Rats; Rats, Inbred F344; RNA, Messenger | 1990 |
Rostral and caudal ventricular infusion of antibodies to dynorphin A(1-17) and dynorphin A(1-8): effects on electrically-elicited feeding in the rat.
Topics: Animals; Brain; Dynorphins; Electric Stimulation; Feeding Behavior; Immune Sera; Injections, Intraventricular; Male; Peptide Fragments; Rats; Rats, Inbred Strains | 1990 |
Synthesis and structure-activity relationships of [MeTyr1, MeArg7]-dynorphin A(1-8)-OH analogues with substitution at position 8.
Topics: Animals; Dynorphins; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Peptide Fragments; Rabbits; Structure-Activity Relationship | 1990 |
Kappa opiate receptors inhibit release of oxytocin from the magnocellular system during dehydration.
Topics: Animals; Benzomorphans; Dehydration; Dynorphins; Endorphins; Hypertonic Solutions; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Osmolar Concentration; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Vasopressins | 1990 |
Naloxone potentiates contractile responses to epinephrine in isolated canine arteries.
Topics: Animals; Clonidine; Corticosterone; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Dynorphins; Epinephrine; Muscle Contraction; Muscle, Smooth, Vascular; Naloxone; Norepinephrine; Peptide Fragments; Phenylephrine; Receptors, Opioid; Renal Artery | 1990 |
An inhibitor of endopeptidase-24.15 blocks the degradation of intraventricularly administered dynorphins.
Topics: Animals; Brain; Captopril; Cerebral Ventricles; Choroid Plexus; Dynorphins; Enkephalin, Leucine; Kinetics; Leucine; Male; Metalloendopeptidases; Neprilysin; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Inbred Strains | 1990 |
Evidence that the agonist action of dynorphin A(1-8) in the guinea-pig myenteric-plexus may be mediated partly through conversion to [Leu5]enkephalin.
Topics: Animals; Dynorphins; Enkephalin, Leucine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Myenteric Plexus; Naltrexone; Narcotic Antagonists; Peptide Fragments; Receptors, Opioid | 1990 |
Hippocampal levels of dynorphin A (1-8) in neonatal and 16-week-old spontaneously hypertensive rats: comparisons with DOCA-salt hypertension.
Topics: Animals; Animals, Newborn; Antihypertensive Agents; Desoxycorticosterone; Disease Models, Animal; Dynorphins; Enkephalin, Methionine; Hippocampus; Hypertension; Peptide Fragments; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Sodium Chloride | 1990 |
Immunocytochemical identification of long ascending peptidergic neurons contributing to the spinoreticular tract in the rat.
Topics: Afferent Pathways; Animals; Benzofurans; Dynorphins; Fluorescent Dyes; Immunohistochemistry; Male; Neuropeptides; Peptide Fragments; Rats; Rats, Inbred Strains; Reticular Formation; Sincalide; Somatostatin; Spinal Cord; Substance P | 1987 |
Release of a dynorphin A (1-8) degrading enzyme from the spinal cord by intraventricular morphine in the rat.
Topics: Animals; Aprotinin; Bacitracin; Binding, Competitive; Dynorphins; Injections, Intraventricular; Kinetics; Male; Morphine; Neuropeptides; Peptide Fragments; Peptide Hydrolases; Rats; Rats, Inbred Strains; Spinal Cord; Thiorphan; Tiopronin | 1988 |
Elevated CSF dynorphin A [1-8] in Tourette's syndrome.
Topics: Dynorphins; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Peptide Fragments; Reference Values; Tourette Syndrome; Tryptophan; Tyrosine | 1988 |
Studies of peptidergic input to the lateral spinal nucleus.
Topics: Animals; Dynorphins; Enkephalin, Methionine; Fluorescent Antibody Technique; FMRFamide; Immune Sera; Laminectomy; Male; Neuropeptides; Peptide Fragments; Rats; Rats, Inbred Strains; Somatostatin; Spinal Cord; Substance P | 1988 |
Biochemical mapping of cholecystokinin-, substance P-, [Met]enkephalin-, [Leu]enkephalin- and dynorphin A (1-8)-like immunoreactivities in the human cerebral cortex.
Topics: Aged; Aged, 80 and over; Cerebral Cortex; Cholecystokinin; Dynorphins; Enkephalins; Female; Humans; Male; Peptide Fragments; Radioimmunoassay; Substance P | 1988 |
Gonadal steroids and anterior lobe dynorphin in the male rat.
Topics: Animals; Chromatography, High Pressure Liquid; Dihydrotestosterone; Dynorphins; Hypothalamic Hormones; Hypothalamus; Male; Orchiectomy; Peptide Fragments; Pituitary Gland; Rats; Rats, Inbred Strains | 1989 |
Beta-adrenergic and opioid receptors on pituicytes cultured from adult rat neurohypophysis: regulation of cell morphology.
Topics: Animals; Antigens, Surface; Cells, Cultured; Dynorphins; Glial Fibrillary Acidic Protein; Male; Naloxone; Peptide Fragments; Pituitary Gland, Posterior; Rats; Receptors, Adrenergic, beta; Receptors, Opioid; Thy-1 Antigens | 1989 |
A low hippocampal dynorphin A (1-8) immunoreactivity in spontaneously hypertensive rats.
Topics: Aging; Animals; Brain Chemistry; Dynorphins; Hippocampus; Hypertension; Hypothalamus; Male; Peptide Fragments; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY | 1989 |
Measurement and chromatographic characterization of prodynorphin-derived peptides in the guinea-pig ileum.
Topics: Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalins; Guinea Pigs; Ileum; Peptide Fragments; Protein Precursors; Radioimmunoassay | 1989 |
Peripheral inflammation is associated with increased dynorphin immunoreactivity in both projection and local circuit neurons in the superficial dorsal horn of the rat lumbar spinal cord.
Topics: Animals; Cell Count; Dynorphins; Fluorescent Dyes; Immunohistochemistry; Inflammation; Male; Peptide Fragments; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains; Spinal Cord | 1989 |
L(+)-2-amino-4-phosphonobutyrate inhibits the release of both glutamate and dynorphin from guinea pig but not rat hippocampal mossy fiber synaptosomes.
Topics: Aminobutyrates; Animals; Dynorphins; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Synaptosomes | 1989 |
Dynorphin A(1-8) immunoreactive cell bodies, dendrites and terminals are postsynaptic to calcitonin gene-related peptide primary afferent terminals in the monkey dorsal horn.
Topics: Animals; Calcitonin Gene-Related Peptide; Dendrites; Dynorphins; Fluorescent Dyes; Immunohistochemistry; Macaca; Macaca fascicularis; Nerve Endings; Neurons, Afferent; Peptide Fragments; Spinal Cord; Stilbamidines | 1989 |
Effects of calcium antagonists on the evoked release of dynorphin A(1-8) and availability of intraterminal calcium in rat hippocampal mossy fiber synaptosomes.
Topics: Animals; Calcium; Calcium Channel Blockers; Cinnarizine; Dynorphins; Flunarizine; Hippocampus; Peptide Fragments; Rats; Synaptosomes | 1989 |
BOAA selectively enhances L-glutamate release from guinea pig hippocampal mossy fiber synaptosomes.
Topics: Alanine; Amino Acids, Diamino; Animals; beta-Alanine; Cyanobacteria Toxins; Dynorphins; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; Male; Peptide Fragments; Synaptosomes | 1989 |
Dynorphin-A (1-8) is contained within perikarya, nerve fibres and nerve terminals of rat duodenum.
Topics: Animals; Duodenum; Dynorphins; Fluorescent Antibody Technique; Histocytochemistry; Male; Myenteric Plexus; Nerve Endings; Nerve Fibers; Nerve Tissue Proteins; Neurons; Peptide Fragments; Rats; Rats, Inbred Strains | 1985 |
Electrophysiological effects of dynorphin peptides on hippocampal pyramidal cells in rat.
Topics: Animals; Cyclazocine; Dynorphins; Electrophysiology; Endorphins; Enkephalin, Leucine; Ethylketocyclazocine; gamma-Aminobutyric Acid; Hippocampus; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid | 1985 |
Analysis of opioid and non-opioid end products of pro-dynorphin in the substantia nigra of the rat.
Topics: Animals; Dynorphins; Endorphins; Male; Peptide Fragments; Protein Precursors; Rats; Rats, Inbred Strains; Substantia Nigra | 1985 |
Adrenorphin immunoreactivity in rat brain.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Methionine; Fluorescent Antibody Technique; Hypothalamus; Peptide Fragments; Protein Precursors; Radioimmunoassay; Rats | 1985 |
[3H]-Dynorphin A (1-8): degradation profile and binding characteristics in brain homogenates.
Topics: Animals; Brain; Captopril; Dynorphins; Guinea Pigs; Leucine; Peptide Fragments; Receptors, Opioid; Receptors, Opioid, kappa | 1985 |
Lower CSF level of dynorphin(1-8) immunoreactivity in schizophrenic patients.
Topics: Adolescent; Adult; Age Factors; Dynorphins; Female; Humans; Male; Peptide Fragments; Schizophrenia; Sex Factors | 1985 |
Repeated electroconvulsive shocks alter the biosynthesis of enkephalin and concentration of dynorphin in the rat brain.
Topics: Animals; Brain; Dynorphins; Electroshock; Enkephalin, Methionine; Hypothalamus; Male; Peptide Fragments; Protein Biosynthesis; Rats; Rats, Inbred F344; RNA, Messenger; Seizures | 1985 |
Presence of dynorphin-like immunoreactivity but not opiate binding in Walker-256 tumors.
Topics: Animals; Carcinoma 256, Walker; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Hormones, Ectopic; Male; Muscles; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid | 1985 |
Colocalization of dynorphin-A(1-17) and dynorphin-A(1-8) within some perikarya of rat duodenum: immunohistochemical evidence for the presence of two separate dynorphinergic systems.
Topics: Animals; Brain Chemistry; Duodenum; Dynorphins; Enkephalin, Leucine; Fluorescent Antibody Technique; Male; Nerve Fibers; Neurons; Peptide Fragments; Rats; Rats, Inbred Strains; Tissue Distribution | 1985 |
On the origin of Leu-enkephalin and Met-enkephalin in the rat neurohypophysis.
Topics: Animals; Arginine Vasopressin; beta-Endorphin; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Hypothalamus, Middle; Male; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pituitary Gland, Posterior; Protein Precursors; Rats; Rats, Inbred Strains; Rats, Inbred WKY; Sodium Glutamate | 1985 |
Kappa-binding and degradation of [3H]dynorphin A (1-8) and [3H]dynorphin A (1-9) in suspensions of guinea pig brain membranes.
Topics: Animals; Benzomorphans; Binding Sites; Brain; Dynorphins; Guinea Pigs; Kinetics; Membranes; Peptide Fragments; Protease Inhibitors; Receptors, Opioid; Receptors, Opioid, kappa; Substrate Specificity; Temperature | 1985 |
Effects of dehydration on pro-dynorphin derived peptides in the neuro-intermediate lobe of the rat pituitary.
Topics: Animals; beta-Endorphin; Dehydration; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Food Deprivation; Hypothalamus; Male; Peptide Fragments; Pituitary Gland, Posterior; Protein Precursors; Rats; Rats, Inbred Strains | 1985 |
Dynorphin-A(1-8) and gamma-melanotropin exist within different myenteric plexus neurons of rat duodenum.
Topics: Animals; Brain; Duodenum; Dynorphins; Fluorescent Antibody Technique; Male; Melanocyte-Stimulating Hormones; Myenteric Plexus; Neurons; Peptide Fragments; Rats; Rats, Inbred Strains | 1985 |
Opioid binding in a rat neurohypophysial fraction enriched in oxytocin and vasopressin nerve endings.
Topics: Animals; Arginine Vasopressin; Binding Sites; Diprenorphine; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Male; Naloxone; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Rats | 1985 |
Steady state levels of pro-dynorphin-related end products in the striatum and substantia nigra of the adult rhesus monkey.
Topics: Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Corpus Striatum; Dynorphins; Endorphins; Enkephalins; Female; Macaca mulatta; Peptide Fragments; Protein Precursors; Radioimmunoassay; Substantia Nigra | 1985 |
Changes in dynorphin, enkephalin and cholecystokinin content of hippocampus and substantia nigra after amygdala kindling.
Topics: Amygdala; Animals; Cholecystokinin; Dynorphins; Enkephalin, Methionine; Hippocampus; Kindling, Neurologic; Male; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Substantia Nigra | 1986 |
Relationships among concentrations of four opioid neuropeptides and luteinizing hormone-releasing hormone in neural tissues of beef cows following early weaning.
Topics: Animals; beta-Endorphin; Cattle; Dynorphins; Endorphins; Enkephalin, Methionine; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Median Eminence; Peptide Fragments; Pituitary Gland; Preoptic Area; Time Factors; Tissue Distribution; Weaning | 1986 |
Dynorphin 1-8 binds to opiate kappa receptors in the neurohypophysis.
Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Cattle; Dynorphins; In Vitro Techniques; Kinetics; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Radioligand Assay; Receptors, Opioid; Receptors, Opioid, kappa; Vasopressins | 1986 |
Comparative spinal analgesic action of dynorphin1-8, dynorphin1-13, and a kappa-receptor agonist U50,488.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Dose-Response Relationship, Drug; Dynorphins; Injections, Spinal; Male; Morphine; Naloxone; Peptide Fragments; Pyrrolidines; Rats; Rats, Inbred Strains; Reaction Time; Spinal Cord; Time Factors | 1986 |
Opioid peptides in Huntington's disease: alterations in prodynorphin and proenkephalin system.
Topics: Basal Ganglia; Dynorphins; Enkephalin, Methionine; Female; Humans; Huntington Disease; In Vitro Techniques; Male; Middle Aged; Peptide Fragments; Substantia Nigra | 1986 |
Distribution of dynorphin and enkephalin peptides in the rat brain.
Topics: Animals; Brain; Diencephalon; Dynorphins; Endorphins; Enkephalin, Methionine; Female; Fluorescent Antibody Technique; Male; Medulla Oblongata; Mesencephalon; Peptide Fragments; Pons; Rats; Telencephalon | 1986 |
Characterization of opioid receptors in the cat carotid body involved in chemosensory depression in vivo.
Topics: Animals; Carotid Body; Cats; Chemoreceptor Cells; Cyclazocine; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Hypercapnia; Hypoxia; Peptide Fragments; Receptors, Opioid | 1986 |
Synaptosomal membrane-bound form of endopeptidase-24.15 generates Leu-enkephalin from dynorphin1-8, alpha- and beta-neoendorphin, and Met-enkephalin from Met-enkephalin-Arg6-Gly7-Leu8.
Topics: Animals; beta-Endorphin; Brain; Chromatography, High Pressure Liquid; Dynorphins; Endopeptidases; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Male; Metalloendopeptidases; Peptide Fragments; Protease Inhibitors; Protein Precursors; Rats; Rats, Inbred Strains; Synaptic Membranes; Synaptosomes; Trypsin | 1987 |
Regulation of the concentration of dynorphin A1-8 in the striatonigral pathway by the dopaminergic system.
Topics: Animals; Apomorphine; Corpus Striatum; Dopamine; Dynorphins; Haloperidol; Male; Peptide Fragments; Rats; Rats, Inbred F344; Substantia Nigra; Synaptic Transmission | 1986 |
Effect of food deprivation on opioid receptor binding in the brain of lean and fatty Zucker rats.
Topics: Animals; Brain; Dynorphins; Food Deprivation; Kinetics; Male; Obesity; Peptide Fragments; Rats; Rats, Zucker | 1986 |
Increased enkephalin and dynorphin immunoreactivity in the hippocampus of seizure sensitive Mongolian gerbils.
Topics: Animals; Dynorphins; Enkephalin, Methionine; Epilepsy; Female; Gerbillinae; Hippocampus; Immunoenzyme Techniques; Male; Peptide Fragments; Radioimmunoassay | 1987 |
Dynorphin(1-8) immunoreactivity in brainstem and hypothalamic nuclei of normotensive and age-matched hypertensive rat strains.
Topics: Age Factors; Animals; Brain Stem; Dynorphins; Hypertension; Hypothalamus; Male; Peptide Fragments; Preoptic Area; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Tissue Distribution | 1987 |
Identification of dynorphin 1-8 in human placenta by mass spectrometry.
Topics: Chorionic Villi; Chromatography, High Pressure Liquid; Dynorphins; Female; Humans; Mass Spectrometry; Peptide Fragments; Placenta | 1987 |
Time-dependent neurobiological effects of colchicine administered directly into the hippocampus of rats.
Topics: Acoustic Stimulation; Animals; Avoidance Learning; Behavior, Animal; Colchicine; Dynorphins; Enkephalin, Methionine; Hippocampus; Male; Motor Activity; Pain; Peptide Fragments; Rats; Rats, Inbred F344; Reaction Time; Reflex, Startle; Time Factors | 1987 |
Opioid peptides inhibit the release of noradrenaline from slices of rat medial preoptic area.
Topics: Animals; beta-Endorphin; Dynorphins; Electric Stimulation; Endorphins; Enkephalin, Methionine; Female; In Vitro Techniques; Morphine; Neurotransmitter Agents; Norepinephrine; Peptide Fragments; Preoptic Area; Rats; Rats, Inbred Strains | 1987 |
A re-examination of the localization of immunoreactive dynorphin(1-8), [Leu]enkephalin and [Met]enkephalin in the rat neurohypophysis.
Topics: Animals; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Histocytochemistry; Immunoenzyme Techniques; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Rats; Rats, Brattleboro; Rats, Inbred Strains | 1987 |
[Effects of phencyclidine on levels of dynorphin 1-17 and dynorphin 1-8 immunoreactivities in various brain regions].
Topics: Animals; Brain; Dynorphins; Peptide Fragments; Phencyclidine; Rats; Tissue Distribution | 1986 |
Characterization of big dynorphins from rat brain and spinal cord.
Topics: Animals; beta-Endorphin; Brain Chemistry; Chromatography, Gel; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Male; Molecular Weight; Peptide Fragments; Protein Precursors; Rats; Rats, Inbred Strains; Spinal Cord | 1987 |
Neonatal and adult 6-hydroxydopamine-induced lesions differentially alter tachykinin and enkephalin gene expression.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Animals, Newborn; Benzazepines; Corpus Striatum; Dopamine; Dynorphins; Enkephalin, Methionine; Enkephalins; Ergolines; Female; Gene Expression Regulation; Hippocampus; Hydroxydopamines; Male; Motor Activity; Neuropeptides; Oxidopamine; Peptide Fragments; Protein Precursors; Quinpirole; Rats; Rats, Inbred Strains; RNA, Messenger; Substantia Nigra; Tachykinins | 1987 |
Kainic acid as a tool to study the regulation and function of opioid peptides in the hippocampus.
Topics: Animals; Dynorphins; Endorphins; Enkephalin, Methionine; Hippocampus; Kainic Acid; Peptide Fragments; Rats; Seizures | 1987 |
Lithium and haloperidol differentially alter the dynorphin A (1-8) and enkephalin levels in the neurointermediate lobe of rat pituitary.
Topics: Animals; Dynorphins; Enkephalins; Haloperidol; Lithium; Male; Peptide Fragments; Pituitary Gland; Rats; Rats, Inbred F344 | 1987 |
Stimulation of the perforant path alters hippocampal levels of opioid peptides, glutamine and GABA.
Topics: Amino Acids; Animals; Dynorphins; Electric Stimulation; Enkephalin, Methionine; gamma-Aminobutyric Acid; Glutamine; Hippocampus; Male; Peptide Fragments; Rats; Rats, Inbred F344; Stereotyped Behavior | 1987 |
Immunoreactive dynorphin is regulated by estrogen in the rat anterior pituitary.
Topics: Animals; Chromatography, High Pressure Liquid; Dynorphins; Estradiol; Female; Hypothalamus; Injections, Intramuscular; Molecular Weight; Ovariectomy; Peptide Fragments; Pituitary Gland, Anterior; Radioimmunoassay; Rats; Rats, Inbred Strains | 1988 |
[Traditional Chinese medicine typing of schizophrenia].
Topics: Adult; Cyclic AMP; Dynorphins; Female; Humans; Male; Medicine, Chinese Traditional; Methoxyhydroxyphenylglycol; Peptide Fragments; Schizophrenia | 1987 |
Electrophysiological evidence for a non-opioid interaction between dynorphin and GABA in the substantia nigra of the rat.
Topics: Action Potentials; Animals; Benzomorphans; Drug Interactions; Dynorphins; gamma-Aminobutyric Acid; Injections, Intravenous; Male; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium Chloride; Substantia Nigra | 1987 |
An examination of the opiate receptor subtypes labeled by [3H]cycloFOXY: an opiate antagonist suitable for positron emission tomography.
Topics: Animals; Autoradiography; Brain; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Naloxone; Naltrexone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Synaptic Membranes; Tomography, Emission-Computed | 1988 |
Dynorphin A inhibits and naloxone increases the electrically stimulated release of oxytocin but not vasopressin from the terminals of the neural lobe.
Topics: Animals; Dynorphins; Electric Stimulation; Male; Models, Biological; Naloxone; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Vasopressins | 1988 |
Beta endorphin and dynorphin levels in rat pituitary and hypothalamus: age studies.
Topics: Aging; Animals; beta-Endorphin; Chromatography, High Pressure Liquid; Dynorphins; Hypothalamo-Hypophyseal System; Male; Peptide Fragments; Radioimmunoassay; Rats; Rats, Inbred Strains | 1988 |
[125I]dynorphin(1-8) produces a similar pattern of kappa-opioid receptor labelling to [3H]dynorphin(1-8) and [3H]etorphine in guinea pig brain: a quantitative autoradiographic study.
Topics: Animals; Autoradiography; Cerebellum; Dynorphins; Etorphine; Frontal Lobe; Guinea Pigs; Morphinans; Peptide Fragments; Radioligand Assay; Receptors, Opioid; Receptors, Opioid, kappa | 1988 |
Lithium increases dynorphin A(1-8) and prodynorphin mRNA levels in the basal ganglia of rats.
Topics: Animals; Basal Ganglia; Chlorides; Corpus Striatum; Dose-Response Relationship, Drug; Dynorphins; Enkephalins; Gene Expression Regulation; Genes; Haloperidol; Immunoenzyme Techniques; Lithium; Lithium Carbonate; Lithium Chloride; Male; Peptide Fragments; Protein Precursors; Rats; Rats, Inbred F344; RNA, Messenger; Transcription, Genetic | 1988 |
Differential activation of spinal cord dynorphin and enkephalin neurons during hyperalgesia: evidence using cDNA hybridization.
Topics: Animals; DNA; Dynorphins; Enkephalin, Methionine; Enkephalins; Hyperalgesia; Hyperesthesia; Male; Nucleic Acid Hybridization; Peptide Fragments; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger | 1988 |
Enkephalin is liberated from metorphamide and dynorphin A1-8 by endo-oligopeptidase A, but not by metalloendopeptidase EC 3.4.24.15.
Topics: Chemical Precipitation; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dynorphins; Enkephalin, Methionine; Enkephalins; Metalloendopeptidases; Peptide Fragments | 1988 |
Decreased [3H]-naloxone binding and elevated dynorphin-A(1-8) content in Zucker rat brain.
Topics: Animals; Body Weight; Brain; Dynorphins; Female; Hypothalamic Area, Lateral; Hypothalamus, Middle; Naloxone; Peptide Fragments; Periaqueductal Gray; Radioligand Assay; Rats; Rats, Zucker; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1988 |
Inactivation of dynorphin-(1-8) in isolated preparations by three peptidases.
Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Dynorphins; Glycopeptides; Guinea Pigs; Hypothalamic Hormones; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle, Smooth; Neprilysin; Oligopeptides; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Protease Inhibitors; Rabbits | 1988 |
Immunocytochemical demonstration of dynorphin(PH-8P)-like immunoreactive elements in the human hypothalamus.
Topics: Dynorphins; Humans; Hypothalamus; Immunohistochemistry; Peptide Fragments | 1988 |
Demonstration of calcitonin gene-related peptide immunoreactive axons contacting dynorphin A(1-8) immunoreactive spinal neurons in a rat model of peripheral inflammation and hyperalgesia.
Topics: Animals; Calcitonin Gene-Related Peptide; Cell Count; Dynorphins; Hyperalgesia; Hyperesthesia; Immunohistochemistry; Inflammation; Male; Neuropeptides; Peptide Fragments; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains; Spinal Cord; Synapses | 1988 |
Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: stimulus specificity, behavioral parameters and opioid receptor binding.
Topics: Animals; Behavior, Animal; Body Weight; Dynorphins; Endorphins; Gene Expression Regulation; Hot Temperature; Hyperalgesia; Inflammation; Male; Peptide Fragments; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord | 1988 |
Estimated membrane structure and receptor subtype selection of an opioid alkaloid-peptide hybrid.
Topics: Animals; Brain; Cell Membrane; Dynorphins; Guinea Pigs; Kinetics; Naltrexone; Peptide Fragments; Receptors, Opioid; Substrate Specificity | 1988 |
Regional distribution of dynorphin and neo-endorphin peptides in rat brain, spinal cord, and pituitary.
Topics: Animals; beta-Endorphin; Brain Chemistry; Chromatography, Gel; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Immune Sera; Male; Peptide Fragments; Peptides; Pituitary Gland; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Tissue Distribution | 1983 |
Evidence for a selective processing of proenkephalin B into different opioid peptide forms in particular regions of rat brain and pituitary.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Brain; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Male; Molecular Weight; Organ Specificity; Peptide Fragments; Pituitary Gland; Pituitary Gland, Posterior; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains | 1984 |
The choice of opioid receptor subtype in isolated preparations by dynorphins.
Topics: Animals; Biological Assay; Dynorphins; Electric Stimulation; Endorphins; Guinea Pigs; Male; Mice; Muscle Contraction; Peptide Fragments; Rats; Receptors, Opioid | 1983 |
A putative processing enzyme from Aplysia that cleaves dynorphin A at the single arginine residue.
Topics: Acetylation; Animals; Aplysia; Arginine; Dynorphins; Endorphins; Peptide Fragments; Peptide Hydrolases; Protease Inhibitors; Substrate Specificity | 1984 |
Relative contents and concomitant release of prodynorphin/neoendorphin-derived peptides in rat hippocampus.
Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalins; Hippocampus; Kinetics; Male; Peptide Fragments; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains | 1983 |
Dynorphin converting enzyme with unusual specificity from rat brain.
Topics: Animals; Brain; Cysteine Endopeptidases; Dynorphins; Endopeptidases; Endorphins; Enkephalins; Hydrogen-Ion Concentration; Kinetics; Male; Peptide Fragments; Protease Inhibitors; Protein Precursors; Rats; Substrate Specificity | 1984 |
Contrasting interactions of the locus coeruleus as compared to the ventral noradrenergic bundle with CNS and pituitary pools of vasopressin, dynorphin and related opioid peptides in the rat.
Topics: Animals; Brain; Cerebral Cortex; Corpus Striatum; Dynorphins; Endorphins; Enkephalin, Methionine; Hippocampus; Hypothalamus; Locus Coeruleus; Neural Pathways; Norepinephrine; Peptide Fragments; Pituitary Gland; Protein Precursors; Rats; Spinal Cord; Vasopressins | 1984 |
Proenkephalin B (prodynorphin)-derived opioid peptides: evidence for a differential processing in lobes of the pituitary.
Topics: Animals; beta-Endorphin; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Male; Molecular Weight; Peptide Fragments; Pituitary Gland; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Tissue Distribution | 1984 |
Receptor preference of dynorphin A fragments in the mouse vas deferens determined by different techniques.
Topics: Animals; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Male; Mice; Naloxone; Naltrexone; Peptide Fragments; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens | 1984 |
Distribution of immunoreactive dynorphin A1-8 in discrete nuclei of the rat brain: comparison with dynorphin A.
Topics: Animals; Brain; Diencephalon; Dynorphins; Endorphins; Hypothalamus; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Telencephalon | 1984 |
Subcellular distribution of opioid peptides in rat hypothalamus and pituitary.
Topics: Animals; Arginine Vasopressin; Centrifugation, Density Gradient; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Hypothalamus; Male; Peptide Fragments; Pituitary Gland; Protein Precursors; Rats; Rats, Inbred Strains; Subcellular Fractions; Synaptic Vesicles; Synaptosomes | 1984 |
Ontogenetic development of the pro-enkephalin B (= pro-dynorphin) opioid peptide system in the rat pituitary.
Topics: Animals; Animals, Newborn; Cell Differentiation; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Female; Male; Molecular Weight; Oxytocin; Peptide Fragments; Peptides; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Pregnancy; Protein Precursors; Rats; Rats, Inbred Strains; Vasopressins | 1984 |
Cardiovascular effects of dynorphin A-(1-8), dynorphin A-(1-13) and dynorphin A-(1-17) microinjected into the preoptic medialis nucleus of the rat.
Topics: Animals; Cardiovascular System; Dynorphins; Male; Peptide Fragments; Preoptic Area; Rats; Rats, Inbred Strains; Respiration | 1984 |
The immunohistochemical localization of nine peptides in the sacral parasympathetic nucleus and the dorsal gray commissure in rat spinal cord.
Topics: Animals; Dynorphins; Endorphins; Enkephalins; FMRFamide; Immunoenzyme Techniques; Male; Neurotensin; Oligopeptides; Pancreatic Polypeptide; Parasympathetic Nervous System; Peptide Fragments; Peptides; Rats; Somatostatin; Spinal Cord; Substance P; Vasoactive Intestinal Peptide | 1984 |
Opioid receptor binding profile of [3H]dynorphin A-(1-8) in rat and guinea pig brain.
Topics: Animals; Binding, Competitive; Brain; Dynorphins; Endorphins; Guinea Pigs; In Vitro Techniques; Male; Narcotics; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Species Specificity | 1984 |
Dynorphin-A-(1-8) is contained within vasopressin neurosecretory vesicles in rat pituitary.
Topics: Animals; Cytoplasmic Granules; Dynorphins; Endorphins; Peptide Fragments; Pituitary Gland, Posterior; Rats; Synaptic Vesicles; Vasopressins | 1983 |
Regional distribution of adrenorphin in rat brain: comparative study with PH-8P.
Topics: Animals; Antibody Specificity; Brain Chemistry; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Methionine; Male; Peptide Fragments; Radioimmunoassay; Rats; Rats, Inbred Strains | 1984 |
A new opioid octapeptide related to dynorphin from porcine hypothalamus.
Topics: Amino Acid Sequence; Animals; Dynorphins; Hypothalamic Hormones; Hypothalamus; Oligopeptides; Peptide Fragments; Radioimmunoassay; Swine | 1980 |
Evidence for the occurrence of the opioid octapeptide dynorphin-(1-8) in the neurointermediate pituitary of rats.
Topics: Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalins; Male; Peptide Fragments; Pituitary Gland, Posterior; Radioimmunoassay; Rats; Rats, Inbred Strains | 1981 |
Dynorphin A(1-8) in human placenta: amino acid sequence determined by tandem mass spectrometry.
Topics: Amino Acid Sequence; Chorionic Villi; Dynorphins; Female; Humans; Molecular Sequence Data; Peptide Fragments; Pregnancy; Pregnancy Proteins; Radioimmunoassay; Radioligand Assay; Spectrometry, Mass, Secondary Ion | 1995 |
Effects of streptozotocin-induced diabetes on prodynorphin-derived peptides in rat brain regions.
Topics: Animals; Brain; Diabetes Mellitus, Experimental; Dynorphins; Enkephalins; Hypothalamic Hormones; Male; Peptide Fragments; Protein Precursors; Rats; Rats, Sprague-Dawley | 1995 |
Prodynorphin-derived peptide expression in primate cortex and striatum.
Topics: Animals; Cerebral Cortex; Corpus Striatum; Dynorphins; Endorphins; Enkephalins; Macaca nemestrina; Peptide Fragments; Protein Precursors; Tissue Distribution | 1994 |
Effects of chronic food restriction on prodynorphin-derived peptides in rat brain regions.
Topics: Animals; Diet; Dynorphins; Enkephalins; Hypothalamic Hormones; Male; Neuropeptides; Peptide Fragments; Protein Precursors; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Receptors mediating depressor responses to intrahippocampal injection of L-glutamate and dynorphin-A(1-8) in conscious, spontaneously hypertensive and normotensive Wistar-Kyoto rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Blood Pressure; Drug Interactions; Dynorphins; Glutamic Acid; Heart Rate; Injections, Intraventricular; Male; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Glutamate; Receptors, Opioid, kappa; Species Specificity | 1994 |
Neurochemical evidence that estrogen-induced suppression of kappa-opioid-receptor-mediated regulation of tuberoinfundibular dopaminergic neurons is prolactin-independent.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain Chemistry; Dopamine; Dynorphins; Estrogens; Female; Hydrazines; Hypothalamic Hormones; Injections, Intraventricular; Median Eminence; Naltrexone; Nerve Endings; Neurons; Ovariectomy; Peptide Fragments; Prolactin; Rats; Receptors, Opioid, kappa | 1994 |
Cardiovascular effects of microinjection of dynorphin-A(1-8) into the hippocampus in conscious, spontaneously hypertensive and normotensive Wistar-Kyoto rats.
Topics: Animals; Blood Pressure; Cardiovascular System; Dose-Response Relationship, Drug; Dynorphins; Hippocampus; Hypertension; Male; Microinjections; Naltrexone; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1994 |
[Alteration of dynorphin1-8 and leu-enkephalin in rat hippocampus during seizure and electroacupuncture].
Topics: Animals; Dynorphins; Electroacupuncture; Enkephalin, Leucine; Epilepsy; Female; Hippocampus; Immunohistochemistry; Male; Penicillins; Peptide Fragments; Rats; Rats, Wistar | 1994 |
Cardiovascular responses to intra-hippocampal dynorphin A-(1-8) in spontaneously hypertensive rats.
Topics: Aging; Amino Acid Sequence; Animals; Blood Pressure; Dose-Response Relationship, Drug; Dynorphins; Heart Rate; Hemodynamics; Hippocampus; Male; Microinjections; Molecular Sequence Data; Naltrexone; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Species Specificity | 1994 |
[3H]dynorphin1-8 binding sites in frog (Rana esculenta) brain membranes.
Topics: Amino Acid Sequence; Animals; Brain; Cell Membrane; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Guanylyl Imidodiphosphate; Molecular Sequence Data; Naloxone; Peptide Fragments; Rana esculenta; Receptors, Opioid; Sodium Chloride; Tritium | 1994 |
66A-078:a kappa-opiate receptor agonist for amelioration of spinal spasticity.
Topics: Animals; Dynorphins; Electroacupuncture; Injections, Spinal; Male; Muscle Spasticity; Parasympatholytics; Peptide Fragments; Rabbits; Random Allocation; Receptors, Opioid, kappa | 1994 |
Dynorphin-A and vasopressin release in the rat: a structure-activity study.
Topics: Analysis of Variance; Animals; Arginine Vasopressin; Cerebral Ventricles; Dynorphins; Immune Sera; In Vitro Techniques; Injections, Intraventricular; Male; Naloxone; Peptide Fragments; Pituitary Gland, Posterior; Radioimmunoassay; Rats; Rats, Wistar; Structure-Activity Relationship; Time Factors | 1994 |
Intrastriatal injections of dynorphin A fragments potentiate the dorsal immobility response in rats.
Topics: Amino Acid Sequence; Animals; Corpus Striatum; Dynorphins; Male; Microinjections; Molecular Sequence Data; Motor Activity; Naloxone; Peptide Fragments; Rats; Stereotyped Behavior | 1993 |
Cellular substrates for interactions between dynorphin terminals and dopamine dendrites in rat ventral tegmental area and substantia nigra.
Topics: Animals; Avidin; Biotin; Dendrites; Dopamine; Dynorphins; Immunoenzyme Techniques; Immunohistochemistry; Male; Microscopy, Immunoelectron; Nerve Endings; Peptide Fragments; Peroxidases; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tegmentum Mesencephali; Tyrosine 3-Monooxygenase | 1993 |
Endogenous opioid regulation of oxytocin secretion through pregnancy in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dynorphins; Electric Stimulation; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Male; Naloxone; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Pregnancy; Pregnancy, Animal; Protein Precursors; Pyrrolidines; Rats; Rats, Wistar; RNA, Messenger; Vasopressins | 1993 |
Endogenous dynorphin modulates calcium-mediated antinociception in mice.
Topics: Animals; Calcium; Dynorphins; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Nociceptors; Peptide Fragments; Phenobarbital | 1993 |
Conversion of dynorphin A(1-8) to [Leu5]-enkephalin in rat central nervous tissue during development.
Topics: Aging; Animals; Animals, Newborn; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Dynorphins; Enkephalin, Methionine; Peptide Fragments; Rats; Rats, Wistar; Spinal Cord | 1993 |
Expression of prodynorphin-derived peptides and mRNA in guinea-pig cortex.
Topics: Animals; Blotting, Northern; Cerebral Cortex; Corpus Striatum; Dynorphins; Endorphins; Enkephalins; Guinea Pigs; Male; Organ Specificity; Peptide Fragments; Protein Precursors; Radioimmunoassay; RNA, Messenger | 1993 |
[Effects of dynorphin A (1-8) on cell cycle and total cellular protein during neuronal aging in vitro].
Topics: Animals; Cell Cycle; Cellular Senescence; Culture Media, Serum-Free; DNA; Dynorphins; Mice; Neuroblastoma; Peptide Fragments; Protein Biosynthesis; Tumor Cells, Cultured | 1995 |
Kappa-opioid receptor modulation of the release of substance P in the dorsal horn.
Topics: Animals; Basal Metabolism; Dynorphins; Hindlimb; Hot Temperature; Intercellular Signaling Peptides and Proteins; Male; Pain; Peptide Fragments; Peptides; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Opioid, kappa; Spinal Cord; Substance P | 1996 |
Radioligand-dependent discrepancy in agonist affinities enhanced by mutations in the kappa-opioid receptor.
Topics: Animals; Benzofurans; COS Cells; Diprenorphine; Dynorphins; Kinetics; Mutation; Narcotic Antagonists; Peptide Fragments; Pyrrolidines; Radioligand Assay; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Fusion Proteins; Tritium | 1996 |
Spinal release of immunoreactive dynorphin A(1-8) with the development of peripheral inflammation in the rat.
Topics: Animals; Dynorphins; Functional Laterality; Immunologic Techniques; Inflammation; Male; Peptide Fragments; Physical Stimulation; Pressure; Rats; Rats, Wistar; Reference Values; Spinal Cord; Tarsus, Animal | 1996 |
Inhibition of lipopolysaccharide-induced nitric oxide and cytokine production by ultralow concentrations of dynorphins in mixed glia cultures.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cells, Cultured; Dynorphins; Lipopolysaccharides; Mice; Naltrexone; Neuroglia; Nitric Oxide; Peptide Fragments; Pyrrolidines; Tumor Necrosis Factor-alpha | 1997 |
Dynorphin-(1-8) inhibits the release of substance P-like immunoreactivity in the spinal cord of rats following a noxious mechanical stimulus.
Topics: Animals; Decerebrate State; Dynorphins; Hindlimb; Male; Naltrexone; Pain; Peptide Fragments; Physical Stimulation; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Opioid, kappa; Spinal Cord; Substance P | 1997 |
Dynorphin A(1-8): stability and implications for in vitro opioid activity.
Topics: Animals; Binding, Competitive; Drug Stability; Dynorphins; Enkephalins; Guinea Pigs; Male; Mice; Muscles; Myenteric Plexus; Opioid Peptides; Peptide Fragments; Rats; Receptors, Opioid, kappa; Tumor Cells, Cultured; Vas Deferens | 1998 |
Protection against dynorphin-(1-8) hydrolysis in membrane preparations by the combination of amastatin, captopril and phosphoramidon.
Topics: Animals; Anti-Bacterial Agents; Biotransformation; Captopril; Chromatography, High Pressure Liquid; Dynorphins; Electrochemistry; Glycopeptides; Guinea Pigs; Hydrolysis; Hypothalamic Hormones; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Mice, Inbred ICR; Peptide Fragments; Peptides; Protease Inhibitors; Receptors, Opioid, delta; Receptors, Opioid, kappa | 1998 |
Diminution of contractile response by kappa-opioid receptor agonists in isolated rat ventricular cardiomyocytes is mediated via a pertussis toxin-sensitive G protein.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antihypertensive Agents; Cells, Cultured; Drug Interactions; Dynorphins; GTP-Binding Proteins; Heart Ventricles; Male; Myocardial Contraction; Peptide Fragments; Pertussis Toxin; Rats; Rats, Wistar; Receptors, Opioid, kappa; Virulence Factors, Bordetella | 1998 |
Identification of synaptic metabolites of dynorphin A (1-8) by electrospray ionization and tandem mass spectrometry.
Topics: Animals; Dynorphins; Hypothalamic Hormones; Kinetics; Male; Mass Spectrometry; Peptide Fragments; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Membranes | 1998 |
Systemic effects of E-2078, a stabilized dynorphin A(1-8) analog, in rhesus monkeys.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Conditioning, Operant; Discrimination, Psychological; Diuresis; Dynorphins; Ethylketocyclazocine; Female; Food; Injections, Intramuscular; Injections, Subcutaneous; Macaca mulatta; Male; Pain Measurement; Peptide Fragments; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1999 |
Cerebrospinal fluid dynorphin A[1-8] and beta-endorphin levels in Tourette's syndrome are unaltered.
Topics: Analysis of Variance; beta-Endorphin; Biomarkers; Case-Control Studies; Dynorphins; Humans; Peptide Fragments; Tourette Syndrome | 1999 |
Chronic exposure to antibodies directed against anti-opiate peptides alter delta-opioid receptor levels.
Topics: alpha-MSH; Animals; Antibodies; Autoradiography; Brain; Dynorphins; Male; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Opioid-Related Disorders; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Tissue Distribution | 1999 |
Effects of peptidase inhibitors on anti-nociceptive action of dynorphin-(1-8) in rats.
Topics: Analgesics, Opioid; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Bacterial Agents; Captopril; Drug Interactions; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Glycopeptides; Injections, Intraventricular; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Peptide Fragments; Peptides; Protease Inhibitors; Rats; Rats, Wistar; Receptors, Opioid, mu | 2000 |
Dynorphins directly inhibit neuronal nicotinic acetylcholine receptors in PC12 cells.
Topics: Animals; Dose-Response Relationship, Drug; Dynorphins; Enzyme Inhibitors; Ion Channel Gating; Membrane Potentials; Nerve Growth Factor; Neural Inhibition; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; PC12 Cells; Peptide Fragments; Pertussis Toxin; Rats; Receptors, Nicotinic; Staurosporine; Virulence Factors, Bordetella | 2000 |
Neurokinin A, calcitonin gene-related peptide, and dynorphin A (1-8) in spinal dorsal horn contribute to descending inhibition evoked by nociceptive afferent pathways: an immunocytochemical study.
Topics: Afferent Pathways; Animals; Calcitonin Gene-Related Peptide; Dynorphins; Female; Immunohistochemistry; Lumbar Vertebrae; Male; Neurokinin A; Pain Measurement; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2000 |
Nonpeptide analogues of dynorphin A(1-8): design, synthesis, and pharmacological evaluation of kappa-selective agonists.
Topics: Analgesics, Opioid; Animals; Azocines; Behavior, Animal; Cyclopropanes; Dynorphins; Male; Mice; Models, Molecular; Molecular Mimicry; Pain Measurement; Peptide Fragments; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship | 2000 |
The neuropeptide FF analogue, 1DMe, reduces in vivo dynorphin release from the rat spinal cord.
Topics: Animals; Dose-Response Relationship, Drug; Dynorphins; Injections, Spinal; Male; Models, Animal; Naltrexone; Narcotic Antagonists; Oligopeptides; Peptide Fragments; Perfusion; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Spinal Cord | 2002 |
Effect of prodynorphin-derived opioid peptides on the ovulatory luteinizing hormone surge in the proestrous rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Brain; Dynorphins; Enkephalins; Female; Luteinizing Hormone; Naltrexone; Ovulation; Peptide Fragments; Proestrus; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa | 2002 |
Further studies on possible dynorphin involvement in the ovulatory luteinizing hormone surge in the proestrous rat.
Topics: Animals; Antibodies; Dynorphins; Enkephalins; Female; Luteinizing Hormone; Ovulation; Peptide Fragments; Perfusion; Preoptic Area; Proestrus; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; RNA, Messenger | 2002 |
Peripheral opioidergic regulation of the tracheobronchial mucociliary transport system.
Topics: Aerosols; Animals; beta-Endorphin; Bronchi; Dogs; Drug Synergism; Dynorphins; Enkephalin, Leucine-2-Alanine; In Vitro Techniques; Injections, Intramuscular; Ions; Male; Mucociliary Clearance; Naloxone; Narcotic Antagonists; Peptide Fragments; Sheep; Trachea; Water | 2003 |
New tris-alkoxycarbonyl arginine derivatives for peptide synthesis.
Topics: Arginine; Dynorphins; Methods; Peptide Fragments; Peptides; Thiourea | 2005 |
c-Fos antisense oligodeoxynucleotide offsets behavioral nociceptive responses and both up-regulations of c-Fos protein and dynorphin a (1-8) in dorsal horn: a study using the formalin test in rats.
Topics: Animals; Behavior, Animal; Dynorphins; Female; Formaldehyde; Injections, Spinal; Male; Oligodeoxyribonucleotides, Antisense; Pain; Pain Threshold; Peptide Fragments; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; RNA, Messenger; Up-Regulation | 2005 |
A microdialysis profile of dynorphin A(1-8) release in the rat nucleus accumbens following alcohol administration.
Topics: Animals; Dose-Response Relationship, Drug; Dynorphins; Ethanol; Male; Microdialysis; Nucleus Accumbens; Peptide Fragments; Rats; Rats, Sprague-Dawley; Stress, Physiological; Tail | 2006 |
Defective neuropeptide processing and ischemic brain injury: a study on proprotein convertase 2 and its substrate neuropeptide in ischemic brains.
Topics: Animals; Brain Ischemia; Dynorphins; In Situ Hybridization; Neuropeptides; Peptide Fragments; Proprotein Convertase 2; Rats; Reperfusion; RNA, Messenger; Stroke; Time Factors; Up-Regulation | 2009 |
Effect of acute ethanol administration on the release of opioid peptides from the midbrain including the ventral tegmental area.
Topics: Alcoholism; Animals; beta-Endorphin; Central Nervous System Depressants; Disease Models, Animal; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Methionine; Ethanol; Injections, Intraperitoneal; Male; Mesencephalon; Opioid Peptides; Peptide Fragments; Rats; Rats, Sprague-Dawley; Time Factors; Ventral Tegmental Area | 2009 |
Effects of corticotropin-releasing hormone receptor antagonists on the ethanol-induced increase of dynorphin A1-8 release in the rat central amygdala.
Topics: Amphibian Proteins; Amygdala; Animals; Corticotropin-Releasing Hormone; Dynorphins; Ethanol; Male; Microdialysis; Microinjections; Peptide Fragments; Peptide Hormones; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone | 2011 |
Cannabinoid-1 receptors in the mouse ventral pallidum are targeted to axonal profiles expressing functionally opposed opioid peptides and contacting N-acylphosphatidylethanolamine-hydrolyzing phospholipase D terminals.
Topics: Animals; Dynorphins; Enkephalin, Methionine; Globus Pallidus; Male; Mice; Mice, Inbred C57BL; Microscopy, Immunoelectron; Neurons; Peptide Fragments; Phospholipase D; Presynaptic Terminals; Receptor, Cannabinoid, CB1 | 2012 |
Dynorphin A (1-8) inhibits oxidative stress and apoptosis in MCAO rats, affording neuroprotection through NMDA receptor and κ-opioid receptor channels.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Caspase 3; Dynorphins; Infarction, Middle Cerebral Artery; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Peptide Fragments; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Superoxide Dismutase | 2021 |