Page last updated: 2024-09-02

dynorphin (1-8) and captopril

dynorphin (1-8) has been researched along with captopril in 5 studies

Compound Research Comparison

Studies
(dynorphin (1-8))
Trials
(dynorphin (1-8))
Recent Studies (post-2010)
(dynorphin (1-8))
Studies
(captopril)
Trials
(captopril)
Recent Studies (post-2010) (captopril)
1730310,3201,514890

Protein Interaction Comparison

ProteinTaxonomydynorphin (1-8) (IC50)captopril (IC50)
Leukotriene A-4 hydrolaseHomo sapiens (human)3.6
Angiotensin-converting enzyme Homo sapiens (human)0.084
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.0173
Succinyl-diaminopimelate desuccinylaseHaemophilus influenzae Rd KW203.3
Angiotensin-converting enzymeRattus norvegicus (Norway rat)0.1004
Beta-lactamase Pseudomonas aeruginosa5
Angiotensin-converting enzyme 2 Homo sapiens (human)0.011
Beta-lactamase class B VIM-2 Pseudomonas aeruginosa3.5

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ayala, JM; Molineaux, CJ1
Gillan, MG; Kosterlitz, HW; McKnight, AT; Robson, LE1
Hiranuma, T; Numata, H; Oka, T1
Arai, Y; Hiranuma, T; Iwao, K; Kanai, M; Kitamura, K; Oka, T; Taniguchi, T1
Akahori, K; Iwao, K; Kitamura, K; Oka, T; Yano, H1

Other Studies

5 other study(ies) available for dynorphin (1-8) and captopril

ArticleYear
An inhibitor of endopeptidase-24.15 blocks the degradation of intraventricularly administered dynorphins.
    Journal of neurochemistry, 1990, Volume: 55, Issue:2

    Topics: Animals; Brain; Captopril; Cerebral Ventricles; Choroid Plexus; Dynorphins; Enkephalin, Leucine; Kinetics; Leucine; Male; Metalloendopeptidases; Neprilysin; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Inbred Strains

1990
[3H]-Dynorphin A (1-8): degradation profile and binding characteristics in brain homogenates.
    Neuropeptides, 1985, Volume: 5, Issue:4-6

    Topics: Animals; Brain; Captopril; Dynorphins; Guinea Pigs; Leucine; Peptide Fragments; Receptors, Opioid; Receptors, Opioid, kappa

1985
Inactivation of dynorphin-(1-8) in isolated preparations by three peptidases.
    Japanese journal of pharmacology, 1988, Volume: 47, Issue:4

    Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; Captopril; Dynorphins; Glycopeptides; Guinea Pigs; Hypothalamic Hormones; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle, Smooth; Neprilysin; Oligopeptides; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Protease Inhibitors; Rabbits

1988
Protection against dynorphin-(1-8) hydrolysis in membrane preparations by the combination of amastatin, captopril and phosphoramidon.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Biotransformation; Captopril; Chromatography, High Pressure Liquid; Dynorphins; Electrochemistry; Glycopeptides; Guinea Pigs; Hydrolysis; Hypothalamic Hormones; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Mice, Inbred ICR; Peptide Fragments; Peptides; Protease Inhibitors; Receptors, Opioid, delta; Receptors, Opioid, kappa

1998
Effects of peptidase inhibitors on anti-nociceptive action of dynorphin-(1-8) in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:3

    Topics: Analgesics, Opioid; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Bacterial Agents; Captopril; Drug Interactions; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Glycopeptides; Injections, Intraventricular; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Peptide Fragments; Peptides; Protease Inhibitors; Rats; Rats, Wistar; Receptors, Opioid, mu

2000