Page last updated: 2024-09-04

dx 8951 and pf 04217903

dx 8951 has been researched along with pf 04217903 in 3 studies

Compound Research Comparison

Studies
(dx 8951)
Trials
(dx 8951)
Recent Studies (post-2010)
(dx 8951)
Studies
(pf 04217903)
Trials
(pf 04217903)
Recent Studies (post-2010) (pf 04217903)
73181523022

Protein Interaction Comparison

ProteinTaxonomydx 8951 (IC50)pf 04217903 (IC50)
cGMP-specific 3',5'-cyclic phosphodiesteraseCanis lupus familiaris (dog)8.06
Hepatocyte growth factor receptorHomo sapiens (human)0.0136
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)3.33
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)1.3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10AHomo sapiens (human)2.7

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1

Other Studies

3 other study(ies) available for dx 8951 and pf 04217903

ArticleYear
Highly predictive and interpretable models for PAMPA permeability.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine

2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020