dv 7751a has been researched along with ofloxacin in 3 studies
*Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION. [MeSH]
*Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION. [MeSH]
| Studies (dv 7751a) | Trials (dv 7751a) | Recent Studies (post-2010) (dv 7751a) | Studies (ofloxacin) | Trials (ofloxacin) | Recent Studies (post-2010) (ofloxacin) |
|---|---|---|---|---|---|
| 12 | 1 | 0 | 6,484 | 976 | 1,346 |
| Protein | Taxonomy | dv 7751a (IC50) | ofloxacin (IC50) |
|---|---|---|---|
| DNA gyrase subunit A | Escherichia coli K-12 | 1.5 | |
| DNA gyrase subunit B | Escherichia coli K-12 | 1.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morrissey, I; Smith, JT | 2 |
| Akahane, K; Kato, M; Nomura, M; Shimoda, K | 1 |
3 other study(ies) available for dv 7751a and ofloxacin
| Article | Year |
|---|---|
Activity of new 4-quinolones in combination with erythromycin or tetracycline against S. pneumoniae.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Drug Therapy, Combination; Erythromycin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Pneumococcal Infections; Quinolones; Spiro Compounds; Streptococcus pneumoniae; Tetracycline | 1995 |
The new 4-quinolones DU-6859a and DV-7751a show enhanced activity against Streptococcus pneumoniae.
Topics: Anti-Infective Agents; Culture Media; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Spiro Compounds; Streptococcus pneumoniae | 1995 |
LD50 value, phototoxicity and convulsion induction test of the new quinolone antibacterial agent (S)-10-[(S)-(8-amino-6-azaspiro[3,4]octan-6-yl)]-9-fluoro-2, 3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxyl ic acid hemihydrate in la
Topics: Administration, Oral; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Convulsants; Dermatitis, Phototoxic; Female; Fluoroquinolones; Injections, Intravenous; Lethal Dose 50; Macaca fascicularis; Male; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Ofloxacin; Phenylacetates; Quinolones; Rats; Rats, Sprague-Dawley | 1996 |