dup 697 and indomethacin

dup 697 has been researched along with indomethacin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (50.00)18.2507
2000's5 (27.78)29.6817
2010's3 (16.67)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Anderson, GD; Burton, EG; Cogburn, JN; Collins, JT; Garland, DJ; Gregory, SA; Huang, HC; Isakson, PC; Koboldt, CM; Li, JJ1
Anderson, GD; Collins, JT; Gregory, SA; Koboldt, CM; Li, JJ; Norton, MB; Perkins, WE; Reinhard, EJ; Reitz, DB; Seibert, K1
Casler, JJ; Collins, PW; Gregory, SA; Isakson, PC; Khanna, IK; Koboldt, CM; Koszyk, FJ; Masferrer, JL; Perkins, WE; Seibert, K; Veenhuizen, AW; Weier, RM; Xu, XD; Yu, Y; Zhang, YY1
Brideau, C; Chan, CC; Charleson, S; Deschênes, D; Dubé, D; Ethier, D; Fortin, R; Friesen, RW; Gauthier, JY; Girard, Y; Gordon, R; Greig, GM; Riendeau, D; Savoie, C; Visco, D; Wang, Z; Wong, E; Xu, LJ; Young, RN1
Brideau, C; Chan, CC; Deschênes, D; Dubé, D; Fortin, R; Friesen, RW; Girard, Y; Gordon, R; Riendeau, D; Savoie, C1
Alcaro, S; Bolasco, A; Cirilli, R; Fioravanti, R; Manna, F; Orallo, F; Ortuso, F; Rossi, F1
Alcaro, S; Angeli, A; Angius, R; Bianco, G; Capasso, C; Cottiglia, F; Del Prete, S; Deplano, S; Distinto, S; Fois, B; Gaspari, M; Maccioni, E; Meleddu, R; Melis, C; Ortuso, F; Supuran, CT; Taverna, D; Yanez, M1
Alvarez, L; Boto, A; Columba-Palomares, MC; Garduño-Ramírez, ML; González-Christen, J; Maldonado-Magaña, A; Marquina, S; Razo-Hernández, RS; Romero-Estrada, A; Romero-Estudillo, I; Sánchez-Carranza, JN1
Creely, DP; Gierse, JK; Hauser, SD; Isakson, PC; Koboldt, C; Rangwala, SH; Seibert, K1
Konishi, N; Matsuo, M; Nakamura, K; Ochi, T; Senoh, H; Tojo, T; Tsuji, K1
Chapman, K; McKnight, W; Wallace, JL1
Danon, A; Rimon, G; Rosenstock, M1
Barnett, K; Bell, CJ; Dicay, M; McKnight, W; Sharkey, KA; Wallace, JL1
Danon, A; Rimon, G; Rosenstock, M; Rubin, M1
Izon, DJ; Loftin, C; Spain, LM; Xu, H1
Baydoun, AR; Churchman, A; Hoffman, R1
Bäck, M; Brink, C; Foudi, N; Louedec, L; Michel, JB; Norel, X; Rienzo, M1
Cao, H; Chen, X; Guan, S; He, B; Li, Y; Shi, C; Wang, J; Xu, X; Zhang, S1

Reviews

1 review(s) available for dup 697 and indomethacin

ArticleYear
Synthesis, Biological Evaluation, and Molecular Docking Study of 3-Amino and 3-Hydroxy-
    Journal of natural products, 2022, 04-22, Volume: 85, Issue:4

    Topics: Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Esters; Hydroxyproline; Lipopolysaccharides; Molecular Docking Simulation; NF-kappa B; Oleanolic Acid; Pentacyclic Triterpenes

2022

Other Studies

17 other study(ies) available for dup 697 and indomethacin

ArticleYear
1,2-Diarylcyclopentenes as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents.
    Journal of medicinal chemistry, 1995, Oct-27, Volume: 38, Issue:22

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclooxygenase Inhibitors; Cyclopentanes; Dose-Response Relationship, Drug; Edema; Indomethacin; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Structure; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Sulfonamides; Sulfones

1995
Selective cyclooxygenase inhibitors: novel 1,2-diarylcyclopentenes are potent and orally active COX-2 inhibitors.
    Journal of medicinal chemistry, 1994, Nov-11, Volume: 37, Issue:23

    Topics: Administration, Oral; Animals; Arthritis, Experimental; Cyclooxygenase Inhibitors; Cyclopentanes; Mice; Rats

1994
1,2-Diarylimidazoles as potent, cyclooxygenase-2 selective, and orally active antiinflammatory agents.
    Journal of medicinal chemistry, 1997, May-23, Volume: 40, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Gastrointestinal Diseases; Humans; Imidazoles; Isoenzymes; Membrane Proteins; Mice; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Rats; Structure-Activity Relationship; Sulfonamides; Sulfones

1997
2-Pyridinyl-3-(4-methylsulfonyl)phenylpyridines: selective and orally active cyclooxygenase-2 inhibitors.
    Bioorganic & medicinal chemistry letters, 1998, Oct-06, Volume: 8, Issue:19

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; CHO Cells; Cricetinae; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Humans; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Structure-Activity Relationship

1998
2-heterosubstituted-3-(4-methylsulfonyl)phenyl-5-trifluoromethyl pyridines as selective and orally active cyclooxygenase-2 inhibitors.
    Bioorganic & medicinal chemistry letters, 1999, Jun-21, Volume: 9, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; CHO Cells; Cricetinae; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Structure-Activity Relationship

1999
Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:12

    Topics: Animals; Catalytic Domain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Insecta; Models, Molecular; Molecular Structure; Pyrazoles; Stereoisomerism; Structure-Activity Relationship

2010
Tuning the Dual Inhibition of Carbonic Anhydrase and Cyclooxygenase by Dihydrothiazole Benzensulfonamides.
    ACS medicinal chemistry letters, 2018, Oct-11, Volume: 9, Issue:10

    Topics:

2018
Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase.
    The Biochemical journal, 1995, Jan-15, Volume: 305 ( Pt 2)

    Topics: Animals; Arachidonic Acid; Baculoviridae; Cloning, Molecular; Cyclooxygenase Inhibitors; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Indomethacin; Nitrobenzenes; Oxygen Consumption; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Spodoptera; Sulfonamides; Thiophenes; Time Factors

1995
Studies on anti-inflammatory agents. IV. Synthesis and pharmacological properties of 1,5-diarylpyrazoles and related derivatives.
    Chemical & pharmaceutical bulletin, 1997, Volume: 45, Issue:6

    Topics: Anilides; Animals; Anti-Inflammatory Agents, Non-Steroidal; CHO Cells; Cricetinae; Cyclooxygenase Inhibitors; Indomethacin; Male; Models, Chemical; Models, Molecular; Pyrazoles; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiophenes

1997
Limited anti-inflammatory efficacy of cyclo-oxygenase-2 inhibition in carrageenan-airpouch inflammation.
    British journal of pharmacology, 1999, Volume: 126, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug Interactions; Indomethacin; Inflammation; Isoenzymes; Leukocytes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Thiophenes

1999
PGHS-2 inhibitors, NS-398 and DuP-697, attenuate the inhibition of PGHS-1 by aspirin and indomethacin without altering its activity.
    Biochimica et biophysica acta, 1999, Aug-25, Volume: 1440, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cattle; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Fibroblasts; Humans; Indomethacin; Isoenzymes; Male; Membrane Proteins; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Sulfonamides; Thiophenes

1999
Role of cyclooxygenase-2 in modulating gastric acid secretion in the normal and inflamed rat stomach.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Gastritis; Indomethacin; Iodoacetamide; Isoenzymes; Male; Pentagastrin; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Thiophenes

2000
Prostaglandin H synthase-2 inhibitors interfere with prostaglandin H synthase-1 inhibition by nonsteroidal anti-inflammatory drugs.
    European journal of pharmacology, 2001, Jan-19, Volume: 412, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Cattle; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Ibuprofen; Indomethacin; Isoenzymes; Male; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sulfonamides; Thiophenes

2001
The COX-2 inhibitor NS-398 causes T-cell developmental disruptions independent of COX-2 enzyme inhibition.
    Cellular immunology, 2001, Dec-15, Volume: 214, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Immunologic Deficiency Syndromes; Indomethacin; Isoenzymes; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Nitrobenzenes; Organ Culture Techniques; Prostaglandin-Endoperoxide Synthases; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Sulfonamides; T-Lymphocytes; Thiophenes; Thymus Gland

2001
Inhibition of angiogenic tubule formation and induction of apoptosis in human endothelial cells by the selective cyclooxygenase-2 inhibitor 5-bromo-2-(4-fluorophenyl)-3-(methylsulfonyl) thiophene (DuP-697).
    European journal of pharmacology, 2007, Nov-14, Volume: 573, Issue:1-3

    Topics: Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Caspase Inhibitors; Cells, Cultured; Chromatin Assembly and Disassembly; Collagen; Culture Media, Serum-Free; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprost; Dinoprostone; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Combinations; Endothelial Cells; Flow Cytometry; Humans; Indomethacin; Laminin; Neovascularization, Physiologic; Oligopeptides; Proteoglycans; Thiophenes; Vascular Endothelial Growth Factor A

2007
Altered reactivity to norepinephrine through COX-2 induction by vascular injury in hypercholesterolemic rabbits.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta, Abdominal; Aortic Diseases; Atherosclerosis; Cholesterol; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Induction; Epoprostenol; Hypercholesterolemia; Indomethacin; Male; Norepinephrine; Rabbits; Thiophenes; Vasoconstriction; Vasoconstrictor Agents

2009
Cyclooxygenase-2 regulated by the nuclear factor-κB pathway plays an important role in endometrial breakdown in a female mouse menstrual-like model.
    Endocrinology, 2013, Volume: 154, Issue:8

    Topics: Animals; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Decidua; Endometrium; Female; Gene Expression Regulation, Enzymologic; Humans; Immunohistochemistry; Indomethacin; Leupeptins; Menstruation; Mice; Mice, Inbred C57BL; Models, Animal; NF-kappa B; Promoter Regions, Genetic; Protein Binding; Pyrrolidines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Thiocarbamates; Thiophenes

2013