duocarmycin b2 has been researched along with duocarmycin b1 in 7 studies
| Studies (duocarmycin b2) | Trials (duocarmycin b2) | Recent Studies (post-2010) (duocarmycin b2) | Studies (duocarmycin b1) | Trials (duocarmycin b1) | Recent Studies (post-2010) (duocarmycin b1) |
|---|---|---|---|---|---|
| 13 | 0 | 2 | 9 | 0 | 0 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ichimura, M; Katsumata, S; Nakano, H; Ogawa, T; Takahashi, I; Takahashi, K | 1 |
| Ichimura, M; Katsumata, S; Morimoto, M; Ogawa, T; Takahashi, K | 1 |
| Ichimura, M; Mihara, A; Nakano, H; Ogawa, T; Takahashi, I; Takahashi, K | 1 |
| Gomi, K; Okabe, M; Okamoto, A | 1 |
| Amishiro, N; Gomi, K; Kobayashi, E; Nagamura, S; Okamoto, A; Saito, H | 1 |
| Amishiro, N; Gomi, K; Kobayashi, E; Nagamura, S; Okabe, M; Okamoto, A; Saito, H | 1 |
| Searcey, M | 1 |
1 review(s) available for duocarmycin b2 and duocarmycin b1
| Article | Year |
|---|---|
Duocarmycins--natures prodrugs?
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Cell Survival; DNA; Drug Stability; Duocarmycins; Indoles; Leucomycins; Leukemia L1210; Prodrugs; Pyrroles; Pyrrolidinones; Structure-Activity Relationship; Tumor Cells, Cultured | 2002 |
6 other study(ies) available for duocarmycin b2 and duocarmycin b1
| Article | Year |
|---|---|
Duocarmycins, new antitumor antibiotics produced by Streptomyces; producing organisms and improved production.
Topics: Antibiotics, Antineoplastic; Bromine; Carbon; Chlorine; Chromatography, High Pressure Liquid; Duocarmycins; Fermentation; Humans; Hydrogen-Ion Concentration; Indoles; Kinetics; Metals; Microscopy, Electron, Scanning; Nitrogen; Pyrroles; Pyrrolidinones; Streptomyces | 1991 |
New antitumor antibiotics, duocarmycins B1 and B2.
Topics: Animals; Antibiotics, Antineoplastic; Chemical Phenomena; Chemistry, Physical; Duocarmycins; Fermentation; Indoles; Mice; Pyrrolidinones; Streptomyces | 1989 |
Interconversion and stability of duocarmycins, a new family of antitumor antibiotics: correlation to their cytotoxic and antimicrobial activities in vitro.
Topics: 3T3 Cells; Animals; Antibiotics, Antineoplastic; Cell Division; Cell Line, Transformed; Drug Stability; Duocarmycins; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Pyrroles; Pyrrolidinones; Temperature | 1993 |
Analysis of DNA fragmentation in human uterine cervix carcinoma HeLa S3 cells treated with duocarmycins or other antitumor agents by pulse field gel electrophoresis.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Division; DNA Damage; DNA, Neoplasm; Duocarmycins; Electrophoresis, Agar Gel; HeLa Cells; Humans; Indoles; Pyrrolidinones; Structure-Activity Relationship | 1993 |
Synthesis and antitumor activity of duocarmycin derivatives: a-ring pyrrole compounds bearing 5-membered heteroarylacryloyl groups.
Topics: Acrylates; Animals; Antineoplastic Agents; Blood Cells; Combinatorial Chemistry Techniques; DNA; Duocarmycins; HeLa Cells; Humans; Indoles; Mice; Models, Chemical; Pyrroles; Pyrrolidinones; Sarcoma 180; Structure-Activity Relationship | 1999 |
Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole compounds bearing beta-(5',6',7'-trimethoxy-2'-indolyl)acryloyl group.
Topics: Animals; Antibiotics, Antineoplastic; Cell Division; Duocarmycins; HeLa Cells; Humans; Indoles; Inhibitory Concentration 50; Leukocyte Count; Male; Mice; Neoplasms, Experimental; Platelet Count; Pyrroles; Pyrrolidinones; Time Factors; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |