Compounds > duocarmycin b2
Page last updated: 2024-09-04

duocarmycin b2 and dc 88-a

duocarmycin b2 has been researched along with dc 88-a in 6 studies

Compound Research Comparison

Studies
(duocarmycin b2)		Trials
(duocarmycin b2)		Recent Studies (post-2010)
(duocarmycin b2)		Studies
(dc 88-a)		Trials
(dc 88-a)		Recent Studies (post-2010) (dc 88-a)
130269022

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ichimura, M; Katsumata, S; Nakano, H; Ogawa, T; Takahashi, I; Takahashi, K1
Ichimura, M; Mihara, A; Nakano, H; Ogawa, T; Takahashi, I; Takahashi, K1
Gomi, K; Okabe, M; Okamoto, A1
Amishiro, N; Gomi, K; Kobayashi, E; Nagamura, S; Okamoto, A; Saito, H1
Amishiro, N; Gomi, K; Kobayashi, E; Nagamura, S; Okabe, M; Okamoto, A; Saito, H1
Searcey, M1

Reviews

1 review(s) available for duocarmycin b2 and dc 88-a

ArticleYear
Duocarmycins--natures prodrugs?
    Current pharmaceutical design, 2002, Volume: 8, Issue:15

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Cell Survival; DNA; Drug Stability; Duocarmycins; Indoles; Leucomycins; Leukemia L1210; Prodrugs; Pyrroles; Pyrrolidinones; Structure-Activity Relationship; Tumor Cells, Cultured

2002

Other Studies

5 other study(ies) available for duocarmycin b2 and dc 88-a

ArticleYear
Duocarmycins, new antitumor antibiotics produced by Streptomyces; producing organisms and improved production.
    The Journal of antibiotics, 1991, Volume: 44, Issue:10

    Topics: Antibiotics, Antineoplastic; Bromine; Carbon; Chlorine; Chromatography, High Pressure Liquid; Duocarmycins; Fermentation; Humans; Hydrogen-Ion Concentration; Indoles; Kinetics; Metals; Microscopy, Electron, Scanning; Nitrogen; Pyrroles; Pyrrolidinones; Streptomyces

1991
Interconversion and stability of duocarmycins, a new family of antitumor antibiotics: correlation to their cytotoxic and antimicrobial activities in vitro.
    Oncology research, 1993, Volume: 5, Issue:4-5

    Topics: 3T3 Cells; Animals; Antibiotics, Antineoplastic; Cell Division; Cell Line, Transformed; Drug Stability; Duocarmycins; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Pyrroles; Pyrrolidinones; Temperature

1993
Analysis of DNA fragmentation in human uterine cervix carcinoma HeLa S3 cells treated with duocarmycins or other antitumor agents by pulse field gel electrophoresis.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Division; DNA Damage; DNA, Neoplasm; Duocarmycins; Electrophoresis, Agar Gel; HeLa Cells; Humans; Indoles; Pyrrolidinones; Structure-Activity Relationship

1993
Synthesis and antitumor activity of duocarmycin derivatives: a-ring pyrrole compounds bearing 5-membered heteroarylacryloyl groups.
    Chemical & pharmaceutical bulletin, 1999, Volume: 47, Issue:10

    Topics: Acrylates; Animals; Antineoplastic Agents; Blood Cells; Combinatorial Chemistry Techniques; DNA; Duocarmycins; HeLa Cells; Humans; Indoles; Mice; Models, Chemical; Pyrroles; Pyrrolidinones; Sarcoma 180; Structure-Activity Relationship

1999
Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole compounds bearing beta-(5',6',7'-trimethoxy-2'-indolyl)acryloyl group.
    Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:7

    Topics: Animals; Antibiotics, Antineoplastic; Cell Division; Duocarmycins; HeLa Cells; Humans; Indoles; Inhibitory Concentration 50; Leukocyte Count; Male; Mice; Neoplasms, Experimental; Platelet Count; Pyrroles; Pyrrolidinones; Time Factors; Transplantation, Heterologous; Tumor Cells, Cultured

2000