Page last updated: 2024-08-24

duloxetine hydrochloride and vortioxetine

duloxetine hydrochloride has been researched along with vortioxetine in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's24 (80.00)24.3611
2020's6 (20.00)2.80

Authors

AuthorsStudies
Baldwin, DS; Dragheim, M; Loft, H1
Hansen, T; Katona, C; Olsen, CK1
Chen, Y; Jacobsen, PL; Mahableshwarkar, AR1
Alam, MY; Chen, Y; Jacobsen, PL; Mahableshwarkar, AR; Serenko, M1
Boulenger, JP; Loft, H; Olsen, CK1
Budac, D; du Jardin, KG; Jensen, JB; Pehrson, AL; Sanchez, C; Smagin, G; Song, D1
Chen, Y; Jacobsen, PL; Mahableshwarkar, AR; Simon, JS1
Leiser, SC; Pehrson, AL; Robichaud, PJ; Sanchez, C1
Brignone, M; Ereshefsky, L; Francois, C; Lançon, C; Llorca, PM; Rive, B; Salah, S1
Chen, Y; Jacobsen, PL; Mahableshwarkar, AR; Serenko, M; Trivedi, MH1
Chen, Y; Jacobson, W; Keefe, RS; Mahableshwarkar, AR; Zajecka, J1
Papakostas, GI1
Lee, Y; McIntyre, RS1
Chen, F; Sánchez, C; Waller, JA1
Baldwin, DS; Chrones, L; Florea, I; Nielsen, R; Nomikos, GG; Palo, W; Reines, E1
Li, G; Ma, D; Wang, X1
Andreasen, JT; Haubro, K; Pickering, DS; Refsgaard, LK; Robinson, ES; Stuart, SA1
Gulinello, M; Li, Y; Sanchez, C1
Fuller, RR; Hughes, S; Lacasse, J; Spaulding-Givens, J1
Barbui, C; Breilmann, J; Guaiana, G; Koesters, M; Ostuzzi, G1
Bundgaard, C; Hamilton, C; Ma, Z; Mørk, A; Pehrson, AL; Pérez, PD; Sánchez, C; Zhang, N1
Christensen, MC; Munro, V1
Beyer, JL; Johnson, KG1
Christensen, MC; Loft, H; McIntyre, RS1
Djordjevic, JD; Jasnic, NI; Micov, AM; Pecikoza, UB; Stepanović-Petrović, RM; Todorović, MB; Tomić, MA; Vuković, MJ1
Badcock, PB; Bailey, AP; Cox, GR; Hetrick, SE; McKenzie, JE; Meader, N; Merry, SN; Moller, CI; Sharma, V1
Cipelli, R; Dell'Osso, B; Di Nicola, M; Martinotti, G; Peduto, I; Pugliese, AC; Signorelli, MS; Ventriglio, A1
Alcántara Montero, A; Pacheco de Vasconcelos, SR1
Hatano, M; Ikuta, T; Iwata, N; Kishi, T; Matsuda, Y; Okuya, M; Sakuma, K1
Jovanović, A; Kotur-Stevuljević, J; Labudović-Borović, M; Micov, A; Nastić, K; Pecikoza, U; Stepanović-Petrović, R; Tomić, M1

Reviews

9 review(s) available for duloxetine hydrochloride and vortioxetine

ArticleYear
Relative efficacy and tolerability of vortioxetine versus selected antidepressants by indirect comparisons of similar clinical studies.
    Current medical research and opinion, 2014, Volume: 30, Issue:12

    Topics: Acetamides; Adult; Aged; Antidepressive Agents; Benzofurans; Citalopram; Cyclohexanols; Depressive Disorder, Major; Desvenlafaxine Succinate; Duloxetine Hydrochloride; Female; Humans; Hypnotics and Sedatives; Indoles; Male; Middle Aged; Piperazines; Selective Serotonin Reuptake Inhibitors; Sertraline; Sulfides; Thiophenes; Venlafaxine Hydrochloride; Vilazodone Hydrochloride; Vortioxetine

2014
Antidepressants and their effect on cognition in major depressive disorder.
    The Journal of clinical psychiatry, 2015, Volume: 76, Issue:8

    Topics: Adult; Citalopram; Cognition Disorders; Depressive Disorder, Major; Duloxetine Hydrochloride; Executive Function; Humans; Middle Aged; Piperazines; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Sulfides; Vortioxetine

2015
Cognition in major depressive disorder: a 'Systemically Important Functional Index' (SIFI).
    Current opinion in psychiatry, 2016, Volume: 29, Issue:1

    Topics: Antidepressive Agents; Cognition; Cognition Disorders; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Learning; Mental Recall; Piperazines; Recovery of Function; Serotonin and Noradrenaline Reuptake Inhibitors; Sulfides; Vortioxetine

2016
Vortioxetine versus Duloxetine in the Treatment of Patients with Major Depressive Disorder: A Meta-Analysis of Randomized Controlled Trials.
    Clinical drug investigation, 2016, Volume: 36, Issue:7

    Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Piperazines; Randomized Controlled Trials as Topic; Sulfides; Treatment Outcome; Vortioxetine

2016
Vortioxetine for depression in adults.
    The Cochrane database of systematic reviews, 2017, Jul-05, Volume: 7

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Patient Dropouts; Piperazines; Placebos; Randomized Controlled Trials as Topic; Remission Induction; Serotonin and Noradrenaline Reuptake Inhibitors; Sulfides; Venlafaxine Hydrochloride; Vortioxetine

2017
Advances in Pharmacotherapy of Late-Life Depression.
    Current psychiatry reports, 2018, 04-07, Volume: 20, Issue:5

    Topics: Antidepressive Agents; Aripiprazole; Depression; Depressive Disorder; Drug Resistance; Duloxetine Hydrochloride; Humans; Paroxetine; Quetiapine Fumarate; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Sertraline; Vortioxetine

2018
New generation antidepressants for depression in children and adolescents: a network meta-analysis.
    The Cochrane database of systematic reviews, 2021, 05-24, Volume: 5

    Topics: Adolescent; Antidepressive Agents; Bias; Child; Citalopram; Depressive Disorder, Major; Desvenlafaxine Succinate; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Mirtazapine; Network Meta-Analysis; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Suicidal Ideation; Venlafaxine Hydrochloride; Vilazodone Hydrochloride; Vortioxetine

2021
Role of vortioxetine in the treatment of neuropathic pain.
    Revista espanola de anestesiologia y reanimacion, 2022, Volume: 69, Issue:10

    Topics: Antidepressive Agents; Chronic Pain; Duloxetine Hydrochloride; Humans; Neuralgia; Vortioxetine

2022
Antidepressants for the treatment of adults with major depressive disorder in the maintenance phase: a systematic review and network meta-analysis.
    Molecular psychiatry, 2023, Volume: 28, Issue:1

    Topics: Adult; Amitriptyline; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Desvenlafaxine Succinate; Duloxetine Hydrochloride; Female; Fluoxetine; Fluvoxamine; Humans; Mirtazapine; Network Meta-Analysis; Paroxetine; Randomized Controlled Trials as Topic; Reboxetine; Sertraline; Venlafaxine Hydrochloride; Vortioxetine

2023

Trials

10 trial(s) available for duloxetine hydrochloride and vortioxetine

ArticleYear
A randomised, double-blind, placebo controlled, duloxetine-referenced, fixed-dose study of three dosages of Lu AA21004 in acute treatment of major depressive disorder (MDD).
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2012, Volume: 22, Issue:7

    Topics: Aged; Analysis of Variance; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Logistic Models; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Reference Values; Sulfides; Thiophenes; Treatment Outcome; Vortioxetine

2012
A randomized, double-blind, placebo-controlled, duloxetine-referenced, fixed-dose study comparing the efficacy and safety of Lu AA21004 in elderly patients with major depressive disorder.
    International clinical psychopharmacology, 2012, Volume: 27, Issue:4

    Topics: Aged; Aged, 80 and over; Antidepressive Agents; Cognition Disorders; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Piperazines; Placebos; Psychiatric Status Rating Scales; Sulfides; Thiophenes; Vortioxetine

2012
A randomized, double-blind trial of 2.5 mg and 5 mg vortioxetine (Lu AA21004) versus placebo for 8 weeks in adults with major depressive disorder.
    Current medical research and opinion, 2013, Volume: 29, Issue:3

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Piperazines; Placebos; Sexual Dysfunction, Physiological; Suicidal Ideation; Sulfides; Thiophenes; Treatment Outcome; Vortioxetine

2013
Safety, tolerability, and efficacy of vortioxetine (Lu AA21004) in major depressive disorder: results of an open-label, flexible-dose, 52-week extension study.
    International clinical psychopharmacology, 2014, Volume: 29, Issue:1

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Anxiety; Depression; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Sexual Dysfunction, Physiological; Suicidal Ideation; Sulfides; Thiophenes; Treatment Outcome; Vortioxetine; Weight Gain; Young Adult

2014
Efficacy and safety of vortioxetine (Lu AA21004), 15 and 20 mg/day: a randomized, double-blind, placebo-controlled, duloxetine-referenced study in the acute treatment of adult patients with major depressive disorder.
    International clinical psychopharmacology, 2014, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Aged; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Headache; Humans; Internationality; Male; Middle Aged; Nausea; Piperazines; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Sulfides; Thiophenes; Treatment Outcome; Vortioxetine; Young Adult

2014
A randomised, double-blind, placebo-controlled, duloxetine-referenced study of the efficacy and tolerability of vortioxetine in the acute treatment of adults with generalised anxiety disorder.
    International journal of clinical practice, 2014, Volume: 68, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Piperazines; Sulfides; Thiophenes; Treatment Outcome; Vortioxetine; Young Adult

2014
A randomized, double-blind, duloxetine-referenced study comparing efficacy and tolerability of 2 fixed doses of vortioxetine in the acute treatment of adults with MDD.
    Psychopharmacology, 2015, Volume: 232, Issue:12

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Electrocardiography; Fatigue; Female; Humans; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Sleep Initiation and Maintenance Disorders; Suicidal Ideation; Sulfides; Vortioxetine; Young Adult

2015
A Randomized, Placebo-Controlled, Active-Reference, Double-Blind, Flexible-Dose Study of the Efficacy of Vortioxetine on Cognitive Function in Major Depressive Disorder.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:8

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Cognition Disorders; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neuropsychological Tests; Piperazines; Psychiatric Status Rating Scales; Sulfides; Surveys and Questionnaires; Treatment Outcome; Vortioxetine; Young Adult

2015
Cost per successfully treated patient for vortioxetine versus duloxetine in adults with major depressive disorder: an analysis of the complete symptoms of depression and functional outcome.
    Current medical research and opinion, 2018, Volume: 34, Issue:4

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Cost-Benefit Analysis; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Self Report; Vortioxetine; Young Adult

2018
Vortioxetine improves symptomatic and functional outcomes in major depressive disorder: A novel dual outcome measure in depressive disorders.
    Journal of affective disorders, 2018, Volume: 227

    Topics: Adult; Aged; Cognition; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Outpatients; Psychometrics; Psychotherapy; Self Report; Surveys and Questionnaires; Vortioxetine; Young Adult

2018

Other Studies

11 other study(ies) available for duloxetine hydrochloride and vortioxetine

ArticleYear
Vortioxetine, but not escitalopram or duloxetine, reverses memory impairment induced by central 5-HT depletion in rats: evidence for direct 5-HT receptor modulation.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Citalopram; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Exploratory Behavior; Female; Hippocampus; Maze Learning; Memory Disorders; Phenylalanine; Piperazines; Protein Binding; Rats; Rats, Long-Evans; Recognition, Psychology; Selective Serotonin Reuptake Inhibitors; Serotonin; Sulfides; Thiophenes; Vortioxetine

2014
Multimodal antidepressant vortioxetine increases frontal cortical oscillations unlike escitalopram and duloxetine--a quantitative EEG study in rats.
    British journal of pharmacology, 2014, Volume: 171, Issue:18

    Topics: Animals; Antidepressive Agents; Citalopram; Duloxetine Hydrochloride; Electroencephalography; Frontal Lobe; Male; Piperazines; Rats, Sprague-Dawley; Receptors, Serotonin; RNA-Binding Proteins; Sulfides; Thiophenes; Vortioxetine; Wakefulness

2014
Vortioxetine promotes maturation of dendritic spines in vitro: A comparative study in hippocampal cultures.
    Neuropharmacology, 2016, Volume: 103

    Topics: Animals; Antidepressive Agents; Cells, Cultured; Dendritic Spines; Duloxetine Hydrochloride; Fluoxetine; Hippocampus; Ketamine; Piperazines; Rats, Sprague-Dawley; Serotonin and Noradrenaline Reuptake Inhibitors; Sulfides; Synapses; Vortioxetine

2016
The safety and tolerability of vortioxetine: Analysis of data from randomized placebo-controlled trials and open-label extension studies.
    Journal of psychopharmacology (Oxford, England), 2016, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Aged; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Sulfides; Venlafaxine Hydrochloride; Vortioxetine; Young Adult

2016
Effects of sertraline, duloxetine, vortioxetine, and idazoxan in the rat affective bias test.
    Psychopharmacology, 2016, Volume: 233, Issue:21-22

    Topics: Adrenergic alpha-2 Receptor Antagonists; Affect; Animals; Antidepressive Agents; Behavior, Animal; Duloxetine Hydrochloride; Idazoxan; Male; Piperazines; Rats; Rats, Sprague-Dawley; Reward; Selective Serotonin Reuptake Inhibitors; Sertraline; Sulfides; Vortioxetine

2016
Distinct Antidepressant-Like and Cognitive Effects of Antidepressants with Different Mechanisms of Action in Middle-Aged Female Mice.
    The international journal of neuropsychopharmacology, 2017, 06-01, Volume: 20, Issue:6

    Topics: Aging; Animals; Antidepressive Agents; Cognition; Cohort Studies; Depression; Duloxetine Hydrochloride; Female; Fluoxetine; Memory; Mice, Inbred C57BL; Piperazines; Psychotropic Drugs; Random Allocation; Space Perception; Sulfides; Vilazodone Hydrochloride; Visual Perception; Vortioxetine

2017
Adverse effects and treatment satisfaction among online users of four antidepressants.
    Psychiatry research, 2017, Volume: 255

    Topics: Affective Symptoms; Antidepressive Agents; Citalopram; Duloxetine Hydrochloride; Humans; Internet; Mental Disorders; Patient Satisfaction; Piperazines; Sulfides; Vilazodone Hydrochloride; Vortioxetine

2017
Acute effects of vortioxetine and duloxetine on resting-state functional connectivity in the awake rat.
    Neuropharmacology, 2018, Volume: 128

    Topics: Animals; Antidepressive Agents; Brain; Duloxetine Hydrochloride; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Neural Pathways; Oxygen; Piperazines; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Rest; Sulfides; Vortioxetine; Wakefulness

2018
Vortioxetine reduces pain hypersensitivity and associated depression-like behavior in mice with oxaliplatin-induced neuropathy.
    Progress in neuro-psychopharmacology & biological psychiatry, 2020, 12-20, Volume: 103

    Topics: Animals; Antidepressive Agents; Antineoplastic Agents; Behavior, Animal; Brain Stem; Depression; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Oxaliplatin; Pain Measurement; Peripheral Nervous System Diseases; Serotonin; Swimming; Vortioxetine

2020
Adherence to, and Persistence of, Antidepressant Therapy in Patients with Major Depressive Disorder: Results from a Population-based Study in Italy.
    Current neuropharmacology, 2023, Volume: 21, Issue:3

    Topics: Adult; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Duloxetine Hydrochloride; Escitalopram; Humans; Italy; Paroxetine; Retrospective Studies; Sertraline; Venlafaxine Hydrochloride; Vortioxetine

2023
The antidepressant drugs vortioxetine and duloxetine differentially and sex-dependently affect animal well-being, cognitive performance, cardiac redox status and histology in a model of osteoarthritis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 166

    Topics: Animals; Antidepressive Agents; Cognition; Duloxetine Hydrochloride; Female; Hyperalgesia; Hypersensitivity; Myocytes, Cardiac; Osteoarthritis; Rats; Vortioxetine

2023