duloxetine hydrochloride has been researched along with thiophenes in 1100 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.09) | 18.7374 |
| 1990's | 25 (2.27) | 18.2507 |
| 2000's | 534 (48.55) | 29.6817 |
| 2010's | 533 (48.45) | 24.3611 |
| 2020's | 7 (0.64) | 2.80 |
| Authors | Studies |
|---|---|
| Bymaster, FP; Krushinski, JH; Reid, LR; Robertson, DW; Wong, DT | 1 |
| Fuller, RW; Hemrick-Luecke, SK; Snoddy, HD | 1 |
| Engleman, EA; Mayle, DA; Perry, KW; Wong, DT | 1 |
| Katofiasc, MA; Thor, KB | 1 |
| Ikeda, M; Kihara, T | 1 |
| Eigyo, M; Ibii, N; Ikeda, M; Ishibashi, C; Katoh, A; Matsushita, A; Naitoh, Y; Takeuchi, M | 1 |
| Bymaster, FP; Krushinski, JH; Mayle, DA; Reid, LR; Robertson, DW; Wong, DT | 1 |
| Engleman, EA; Perry, KW; Robertson, DW; Thompson, DC; Wong, DT | 1 |
| Blier, P; De Montigny, C; Kasamo, K | 1 |
| Leonard, BE | 1 |
| Ishigooka, J; Kasahara, T; Miura, S; Murasaki, M; Nagata, E | 2 |
| Cistarelli, JM; Gobert, A; Millan, MJ; Rivet, JM | 1 |
| Lakoski, JM; Smith, JE | 3 |
| Berk, M; Birkett, M; du Plessis, AD; Richardt, D | 1 |
| Pinder, RM | 1 |
| Cistarelli, L; Gobert, A; Melon, C; Millan, MJ; Rivet, JM | 1 |
| Flores-Hernández, J; Galarraga, E; Góngora-Alfaro, JL; Hernández-López, S | 1 |
| Baertschi, SW; Jansen, PJ; Kemp, CA; Maple, SR; Oren, PL | 1 |
| Brocco, M; Cistarelli, L; Gobert, A; Melon, C; Millan, MJ; Veiga, S | 1 |
| Lucki, I; Rénéric, JP | 1 |
| Blier, P; De Montigny, C; Rueter, LE | 1 |
| Blier, P; de Montigny, C; Kasamo, K; Rueter, LE | 1 |
| Voelker, R | 1 |
| Anthonsen, T; Hoff, BH; Liu, H | 1 |
| Cerimele, BJ; Goldberg, MJ; Sharma, A | 1 |
| Pitsikas, N | 1 |
| Blier, P; de Montigny, C; Debonnel, G; Hébert, C; Turcotte, JE | 1 |
| Bymaster, FP; Dreshfield-Ahmad, LJ; Hemrick-Luecke, SK; Nelson, DL; Shaw, JL; Thompson, L; Threlkeld, PG; Wong, DT | 1 |
| Demitrack, MA; Goldstein, DJ; Lu, Y; Mallinckrodt, C | 1 |
| Fava, M | 1 |
| Demitrack, MA; Detke, MJ; Goldstein, DJ; Hayes, JR; Lu, Y | 1 |
| Bymaster, FP; Wong, DT | 1 |
| Audia, JE; Katofiasc, MA; Nissen, J; Thor, KB | 1 |
| Bump, RC; Norton, PA; Yalcin, I; Zinner, NR | 2 |
| Anttila, S; Leinonen, E | 1 |
| Connoley, IP; Harrison, J; Heal, DJ; Liu, YL; Stock, MJ | 1 |
| Cavanaugh, JE; Karpa, KD; Lakoski, JM | 1 |
| Fishbain, DA | 2 |
| Ayan-Oshodi, M; Gonzales, CR; Knadler, MP; Kuan, HY; Lim, M; Pan, A; Reddy, S; Sathirakul, K; Skinner, MH; Wise, SD; Yeo, KP | 1 |
| Briley, M | 3 |
| Chancellor, MB; Fraser, MO | 1 |
| Stewart, DE | 1 |
| Bieck, PR; Bymaster, FP; Chalon, SA; Granier, LA; Hirth, C; Joliat, MJ; Potter, WZ; Vandenhende, FR | 1 |
| Detke, MJ; Goldstein, DJ; Lu, Y; Mallinckrodt, C; Nemeroff, CB; Schatzberg, AF; Tran, PV | 1 |
| Bump, RC; Yalcin, I | 2 |
| Gillespie, TA; Knadler, MP; Kuan, HY; Kuo, F; Lantz, RJ; Rash, TJ; Skinner, M | 1 |
| Zinner, NR | 1 |
| Detke, MJ; Dunner, DL; Goldstein, DJ; Lu, Y; Mallinckrodt, C | 1 |
| Rovner, ES; Wein, AJ | 1 |
| Bump, RC; Dmochowski, RR; Miklos, JR; Norton, PA; Yalcin, I; Zinner, NR | 1 |
| Thor, KB | 1 |
| Burgard, EC; Fraser, MO; Thor, KB | 1 |
| Baessler, K; Schuessler, B | 1 |
| Schatzberg, AF | 1 |
| Elhilali, M; Khaled, SM | 1 |
| Bymaster, FP; Evans, DC; Hemrick-Luecke, SK; Koch, S; Nelson, DL; Perry, KW; Thompson, LK; Threlkeld, PG | 1 |
| Bump, RC; Viktrup, L | 1 |
| Beedle, EE; Bymaster, FP; Findlay, J; Gallagher, PT; Krushinski, JH; Mitchell, S; Robertson, DW; Thompson, DC; Wallace, L; Wong, DT | 1 |
| Ferguson, MB; Goldstein, DJ; Mallinckrodt, CH; Raskin, J | 1 |
| Leo, RJ | 1 |
| Cannon, TW; Chancellor, MB; Yoshimura, N | 1 |
| Heathman, M; Knadler, MP; Kuan, HY; O'Brien, L; Reddy, S; Seger, ME; Skerjanec, A; Skinner, MH | 1 |
| Bailey, KP | 1 |
| Kranzler, J; Nemeroff, CB; Owens, MJ; Plott, SJ; Rao, SG; Vaishnavi, SN | 1 |
| Bump, RC; Millard, RJ; Moore, K; Rencken, R; Yalcin, I | 1 |
| Abrams, P; Bump, RC; Lange, R; Slack, M; van Kerrebroeck, P; Wyndaele, JJ; Yalcin, I | 1 |
| Angulo, J; Cuevas, B; Cuevas, P; Gupta, S; Sáenz de Tejada, I | 1 |
| Hirschfeld, RM; Vornik, LA | 1 |
| Caccia, S | 1 |
| Chan, C; Gonzales, CR; Hua, TC; Knadler, MP; Pan, A; Poo, YK; Skinner, MH; Wise, SD | 1 |
| Detke, MJ; Fava, M; Mallinckrodt, CH; Watkin, JG; Wohlreich, MM | 1 |
| Benson, JT; Bump, RC; Schäfer, W; Versi, E; Yalcin, I | 1 |
| Cardozo, L | 3 |
| Michel, MC; Peters, SL | 1 |
| Van Kerrebroeck, P | 1 |
| Cabrera Pérez, J; González Enguita, C; Pérez Martínez, FC; Ramírez Pérez del Yerro, M; Vela Navarrete, R | 1 |
| Wyllie, MG | 2 |
| Gillespie, TA; Kulanthaivel, P; Kuo, F; Lantz, RJ; Ma, TW; Nelson, DL; Threlkeld, PG; Wheeler, WJ; Yi, P; Zmijewski, M | 1 |
| Bieck, PR; Black, BK; Bymaster, FP; Garland, EM; Gonzales, C; Loghin, C; Potter, WZ; Robertson, D; Vincent, S | 1 |
| Gray, M | 1 |
| Donatucci, C; Thor, KB | 1 |
| Batallan, A; Dhainaut, C; Madelenat, P; Thoury, A; Yazbeck, C | 1 |
| Demitrack, MA; Detke, MJ; Goldstein, DJ; Lu, Y; Mallinckrodt, C; Wiltse, C | 1 |
| Hemrick-Luecke, SK; Iyengar, S; Simmons, RM; Webster, AA; Xu, JY | 1 |
| Chalon, S; Granier, LA; Lainey, E; Pereira, A; Staner, L; Vandenhende, F; Watkin, JG | 1 |
| Gonzales, JS; Watkin, JG; Wohlreich, MM | 1 |
| Drutz, H | 2 |
| Moore, K | 1 |
| Delgado, PL | 1 |
| Jost, W; Marsalek, P | 1 |
| Jost, WH; Jünemann, KP; Manning, M; Marsalek, P | 1 |
| Preskorn, SH | 2 |
| Baygani, SK; Bump, RC; Cardozo, L; Drutz, HP | 1 |
| Detke, MJ; Mallinckrodt, CH; Raskin, J; Watkin, JG; Wohlreich, MM | 1 |
| Floris, S; Guardianelli, F; Lello, S; Melis, GB; Melis, M; Paoletti, AM | 1 |
| Demitrack, MA | 1 |
| Littlejohn, GO | 1 |
| Arnold, LM; Crofford, LJ; Detke, MJ; Goldstein, DJ; Iyengar, S; Lu, Y; Wohlreich, M | 1 |
| Hsieh, M; Kershen, RT | 1 |
| Jones, CK; Peters, SC; Shannon, HE | 2 |
| Brannan, SK; Brown, EB; Mallinckrodt, CH; Schatzberg, AF; Watkin, JG; Wohlreich, MM | 1 |
| Keating, GM; McCormack, PL | 1 |
| Dugan, SE; Fuller, MA | 1 |
| Liedl, B | 2 |
| Greist, J; Mallinckrodt, CH; McNamara, RK; Raskin, J; Rayamajhi, JN | 1 |
| Rabasseda, X | 1 |
| Knitza, R; Kolben, M; Maurer, S | 1 |
| Miller, MC | 1 |
| Kirkpatrick, P; Waitekus, AB | 1 |
| Bitter, I; Demitrack, MA; Detke, MJ; Mallinckrodt, CH; McNamara, RK; Wiltse, CG | 1 |
| Brannan, SK; Detke, MJ; Mallinckrodt, CH; Tollefson, GD; Watkin, JG | 1 |
| Albano, D; Zajecka, JM | 1 |
| Liu, C; Mallinckrodt, CH; Raskin, J; Watkin, JG; Wohlreich, MM | 1 |
| Martan, A | 1 |
| Banerjee, UC; Soni, P | 1 |
| Blackburn-Munro, G; Bomholt, SF; Mikkelsen, JD | 1 |
| Laustsen, G; Wimmett, L | 1 |
| Branch, RA; Gonzales, C; Knadler, MP; Reddy, S; Skinner, MH; Suri, A | 1 |
| Detke, MJ; Kennedy, JS; Mallinckrodt, CH; Nelson, JC; Watkin, JG; Wohlreich, MM | 1 |
| Kruszewski, SP | 1 |
| Detke, MJ; Mallinckrodt, C; Pangallo, BA; Thase, ME; Tran, PV; Wiltse, C | 1 |
| Laustsen, G; Wimett, L | 1 |
| Schultz-Lampel, D | 1 |
| Cowen, PJ; Gama, J; Ogilvie, AD | 1 |
| McGuire, EJ | 1 |
| Bump, RC; Elser, DM; Freeman, RM; Ghoniem, GM; Van Leeuwen, JS; Yalcin, I; Zhao, YD | 1 |
| Almási, J; Rihmer, Z | 1 |
| Gören, JL; Kirwin, JL | 1 |
| Wein, AJ | 1 |
| Bymaster, FP; Detke, MJ; Iyengar, S; Knadler, MP; Lee, TC | 1 |
| Hudson, JI; Kajdasz, DK; Mallinckrodt, CH; Martynov, OV; Watkin, JG; Wohlreich, MM | 1 |
| Obenchain, RL; Robinson, RL; Swindle, RW | 1 |
| Detke, MJ; Goldstein, DJ; Iyengar, S; Lee, TC; Lu, Y | 1 |
| Amoros, MA; Castro-Diaz, D | 1 |
| Konarski, JZ; McIntyre, RS | 1 |
| Brannan, SK; Delgado, PL; Detke, MJ; Mallinckrodt, CH; McNamara, RK; Tran, PV; Wang, F; Watkin, JG | 1 |
| D'Souza, DN; Detke, MJ; Dunner, DL; Kajdasz, DK; Russell, JM | 1 |
| Grandoso, L; Pineda, J; Torrecilla, M; Ugedo, L | 1 |
| Lenzer, J | 1 |
| Mirza, NR; Nielsen, EØ; Troelsen, KB | 1 |
| Alhasso, AA; Ballantyne, Z; Mariappan, P; N'Dow, JM | 1 |
| Detke, MJ; Hirschfeld, RM; Lee, TC; Mallinckrodt, C | 1 |
| Paraiso, M; Thacker, HL | 1 |
| Marcil, WA; Petty, F | 1 |
| Einarson, TR; van Baardewijk, M; Vis, PM | 2 |
| Guay, DR | 1 |
| Dobson, D; Farde, L; Hall, H; Halldin, C; Innis, RB; Mozley, PD; Pike, VW; Schou, M | 1 |
| Briley, M; Grady, MM; Moret, C; Stahl, SM | 1 |
| Baygani, SK; Hurley, DJ; Turner, CL; Viktrup, L; Yalcin, I | 1 |
| Cobb, C; Crichlow, R | 1 |
| Bettinger, TL; Crismon, ML; Hunziker, ME; Suehs, BT | 1 |
| Mathews, AW | 1 |
| Jost, WH; Marsalek, P; Michel, MC | 1 |
| Gahimer, J; Viktrup, L; Wernicke, JF; Wulster-Radcliffe, M; Yalcin, I | 1 |
| Desaiah, D; Haddad, PM; Kajdasz, DK; Perahia, DG | 1 |
| Andorn, AC; Mallinckrodt, CH; Prakash, A; Watkin, JG; Wohlreich, MM | 1 |
| Fava, M; Mallinckrodt, CH; Martinez, JM; Prakash, A; Watkin, JG; Wohlreich, MM | 1 |
| Crippa, JA; Zuardi, AW | 1 |
| Arnold, LM; D'Souza, DN; Goldstein, DJ; Iyengar, S; Pritchett, YL; Rosen, A; Wernicke, JF | 1 |
| Botts, S | 1 |
| Gayken, J; Haight, R; Westanmo, AD | 1 |
| Walter, S | 1 |
| Kozian, R | 1 |
| Zhao, YD | 1 |
| Fava, M; Hazen, E | 1 |
| Aggarwal, I; Duckett, JR; Patil, A | 1 |
| D'Souza, DN; Iyengar, S; Pritchett, YL; Raskin, J; Smith, TR; Wernicke, JF; Wong, K | 1 |
| Smith, TR | 1 |
| Boy, S; Braun, PM; Haferkamp, A; Knapp, PA; Reitz, A; Schurch, B; Wirth, B | 1 |
| Chartier-Kastler, E; Richard, F; Rouprêt, M | 1 |
| Ammar, H; Malani, AK | 1 |
| Gratzke, C; Reich, O; Schlenker, B; Schorsch, I; Seitz, M; Stief, CG | 1 |
| Bauer, M; Möller, HJ; Schneider, E | 1 |
| Ikoma, Y; Kosaka, J; Nozaki, S; Ota, M; Suhara, T; Suzuki, K; Takano, A; Tanada, S | 1 |
| Chapple, CR | 1 |
| Burns, AM; Fava, M; Fisher, LB; Homberger, CH; Iosifescu, DV; Kinrys, G; Mischoulon, D; Papakostas, GI; Worthington, JJ | 1 |
| Schuessler, B | 1 |
| Freeman, RM | 1 |
| Michel, MC; Oelke, M; Roovers, JP | 1 |
| Maramattom, BV | 1 |
| García, L; Grandoso, L; Pineda, J; Ugedo, L | 1 |
| Bailey, RK; Mallinckrodt, CH; Plewes, JM; Watkin, JG; Wohlreich, MM | 1 |
| Clemens, JW; Detke, MJ; Gilaberte, I; Huckins, SA; Montejo, AL; Montgomery, SA; Perahia, DG; Wang, F; Wiltse, CG | 1 |
| Glueck, CJ; Khalil, Q; Wang, P; Winiarska, M | 1 |
| Onwude, J | 1 |
| Ahearn, EP; Deneys, ML | 1 |
| Frazer, A; Gould, GG; Javors, MA | 1 |
| Allen, A; Dell'Osso, B; Hollander, E; Nestadt, G | 1 |
| Keltner, NL; Lee, SI | 1 |
| Balestrieri, M; Detke, MJ; Fava, M; Perahia, D; Raskin, J; Wang, F | 1 |
| Norman, TR | 1 |
| Friede, T; Kieser, M | 1 |
| Detke, MJ; Mallinckrodt, CH; Perahia, DG; Walker, DJ; Wang, F | 1 |
| Kajdasz, DK; Perahia, DG; Raskin, J; Tylee, A; Walker, DJ | 1 |
| Deuschle, M; Knopf, U; Kuwilsky, A; Mase, E; Zink, M | 1 |
| Das, A; Desarkar, P; Sinha, VK | 1 |
| Bump, RC; Kinchen, K; Patrick, DL; Summers, K; Yalcin, I | 1 |
| Bish, G; Brown, AD; Fish, PV; Jonathan Fray, M; Stobie, A; Wakenhut, F; Whitlock, GA | 1 |
| Berghmans, BC; Brunenberg, DE; Joore, MA; Severens, JL; van der Vaart, CH; Veraart, CP | 1 |
| Birnbaum, HG; Gelwicks, S; Le, TK; Mareva, MN; Robinson, RL; Rosen, A; Wu, EQ | 1 |
| Viktrup, L; Yalcin, I | 1 |
| Kornstein, SG; Mallinckrodt, CH; Stewart, DE; Watkin, JG; Wohlreich, MM | 2 |
| Frankel, WL; Hanje, AJ; Kirkpatrick, RB; Pell, LJ; Votolato, NA | 1 |
| Hanretta, AT; Malek-Ahmadi, P | 1 |
| Kalogirou, G; Papaioannou, P; Zahariou, A | 1 |
| Berezhkovskiy, LM | 1 |
| Carter, WP; Mallinckrodt, CH; Prakash, A; Watkin, JG; Wohlreich, MM | 1 |
| Eckert, L; Lançon, C | 1 |
| Cookson, J; Desaiah, D; Gilaberte, I; Kajdasz, DK | 1 |
| Kajdasz, DK; Perahia, DG; Raskin, J; Royer, MG; Walker, DJ | 1 |
| Russell, JW | 1 |
| Cecconi, F; Del Popolo, G; Filocamo, MT; Li Marzi, V; Marzocco, M; Nicita, G; Villari, D | 1 |
| Bech, P; Kajdasz, DK; Porsdal, V | 1 |
| Hotston, MR; Hurley, K; Patel, S; Persad, R | 1 |
| Borges-Gonzalez, S; Flockhart, D; Preskorn, SH | 1 |
| Desaiah, D; Perahia, DG; Pritchett, YL; Raskin, J | 1 |
| Alhasso, A; Ballantyne, Z; Grant, A; Mariappan, P; N'Dow, J | 1 |
| Blanco, C; Lewis-Fernández, R; Mallinckrodt, CH; Plewes, JM; Watkin, JG; Wohlreich, MM | 1 |
| Eastwood, BJ; Jones, CK; Need, AB; Shannon, HE | 1 |
| D'Souza, DN; Iyengar, S; Pritchett, YL; Raskin, J; Tran, P; Waninger, A; Wernicke, JF | 1 |
| Antsaklis, A; Athanasiou, S; Chaliha, C; Digesu, GA; Georgoulias, N; Khullar, V; Sotiropoulou, M | 1 |
| O'Connor, AB | 1 |
| Cohen, JS; Liu, C; Meadows, ES; Muram, D; Plouffe, L; Weinstein, DL | 1 |
| Acharya, N; Baldessarini, RJ; Cavazzoni, PA; D'Souza, DN; Perahia, DG; Polzer, JP; Rosen, AS | 1 |
| Rudominer, R; Safdieh, JE | 1 |
| Forscher, CA; Kerrihard, TN; Strouse, TB; Zakowski, P | 1 |
| Brown, DR; Keegan, MT; Rabinstein, AA | 1 |
| Deuschle, M; Mase, E; Zink, M | 1 |
| Tobin, ML | 1 |
| Anderson, D; DeQuintana, S; Kegler, S; Lintemoot, J; Muto, J; Reed, S; Sandberg, M | 1 |
| Hajak, G | 1 |
| Ziegler, D | 1 |
| Qu, Y; Rahardja, D; Zhao, YD | 1 |
| Castilla Reparaz, C; Pérez Martínez, FC; Vela Navarrete, R | 1 |
| Bouchard, C; Bump, RC; Carone, R; Castro-Diaz, D; Haab, F; Hampel, C; Palma, PC; Rodriguez Ginorio, H; Voss, S; Yalcin, I; Zepeda Contreras, S | 1 |
| Brenna, E; Frigoli, S; Fronza, G; Fuganti, C; Malpezzi, L | 1 |
| Pitchot, W | 2 |
| Armbruster, M; Boulton, AJ; Hardy, T; Sachson, R; Shen, S | 1 |
| Jimenez-Genchi, A | 1 |
| Ouslander, JG; Zarowitz, BJ | 1 |
| Hertle, L; van Ophoven, A | 1 |
| Baker, B; Burt, T; Desta, Z; Flockhart, D; Greenblatt, DJ; Harmatz, JS; Klick-Davis, A; Luo, Y; Perloff, ES; Preskorn, SH | 1 |
| Krüger, S; Lindstaedt, M | 1 |
| De Las Cuevas, C; Sanz, EJ | 1 |
| Bakhla, A; Desarkar, P; Sinha, VK | 1 |
| Gahimer, J; Ossanna, MJ; Viktrup, L; Wernicke, J; Wulster-Radcliffe, M; Yalcin, I | 1 |
| Cardozo, L; Cartwright, R; Robinson, D; Vella, M | 1 |
| Athanasios, Z; George, K; Polyanthi, P | 1 |
| Appell, RA; Davila, GW | 1 |
| Greist, JH; Mallinckrodt, CH; Nierenberg, AA; Prakash, A; Sambunaris, A; Tollefson, GD; Wohlreich, MM | 1 |
| Buse, S; Haferkamp, A; Hohenfellner, M; Reitz, A | 1 |
| Ball, S; Detke, MJ; Dinkel, J; Erickson, J; Raskin, J; Rickels, K; Russell, J; Rynn, M | 1 |
| Chen, BM; Feng, S; Li, HD; Ma, N; Wang, F; Xiang, DX; Xu, P; Zhang, BK; Zhu, RH; Zhu, YG | 1 |
| Ezzo, DC; Patel, PN | 1 |
| Chappell, AS; Desaiah, D; Hall, JA; Pritchett, YL; Robinson, MJ; Wang, F; Ziegler, D | 1 |
| Calabrese, F; Cattaneo, A; Gennarelli, M; Maj, PF; Molteni, R; Racagni, G; Riva, MA | 1 |
| Kluge, M; Schüssler, P; Steiger, A | 1 |
| Meighen, KG | 1 |
| Knadler, MP; Kuo, F; McCulloch, JD; Satonin, DK | 1 |
| Aubry, JM; Barbe, R; Bertschy, G; Bryois, C; Delini-Stula, A; Gervasoni, N; Merlo, M | 1 |
| Basu, M; Duckett, JR; Kavalakuntla, G; Vella, M | 1 |
| Baram, D; Espeleta, VJ; Kane, PB; Moore, WH | 1 |
| Chan, C; Knadler, MP; Lim, M; Pan, AX; Small, DS; Yeo, KP | 1 |
| Callaghan, JT; Chappell, J; Derby, M; Desaiah, D; Ereshefsky, L; Francis, JL; Gonzales, CR; Hoelscher, D; Knadler, MP; Leese, PT; Leibowitz, M; Small, D; Zhang, L | 1 |
| Ballesteros, J; Callado, LF; Gutiérrez, M | 1 |
| Ball, S; Detke, M; Dinkel, J; Dunayevich, E; Erickson, J; Hartford, J; Kornstein, S; Liebowitz, M; Pigott, T; Russell, J; Walker, D | 1 |
| Terneus, W | 1 |
| Bauer, M; Froud, DM; Jain, R; Kajdasz, DK; Perahia, DG; Pritchett, YL; Raskin, J; Russell, JM; Spencer, KA; Thase, ME; Walker, DJ | 1 |
| Kajdasz, DK; Lledó, A; Raskin, J; Wang, F; Wernicke, J | 1 |
| Colman, SA; Harrison, GA; Hong, JP; Lee, MS; Lee, P; Liu, CY; Raskin, J; Ruschel, S; Shu, L; Wang, CY; Xu, X | 1 |
| Ball, SG; Detke, MJ; Endicott, J; Erickson, J; Marciniak, M; Raskin, J; Russell, JM; Swindle, RW | 1 |
| Dilla, T; Espuña Pons, M; Puig Clota, M; Rebollo Alvarez, P | 1 |
| Emanuele, E; Politi, P | 1 |
| Crippa, JA; Filho, AS; Freitas, MC; Zuardi, AW | 1 |
| Dirks, AC; van Hyfte, DM | 1 |
| Aboujaoude, EN; Gamel, NN; Koran, LM | 1 |
| Wallace, JM | 1 |
| Bump, RC; Herschorn, S; Kreder, KJ; Moore, K; Steers, WD; Strohbehn, K; Yalcin, I | 1 |
| Detke, MJ; Faries, DE; Mallinckrodt, CH; Meyers, AL; Prakash, A | 1 |
| Dinkel, JJ; Mohs, RC; Raskin, J; Rotz, BT; Sheikh, J; Siegal, A; Wiltse, CG; Xu, J | 1 |
| Maltsman-Tseikhin, A; Moricca, P; Niv, D | 1 |
| Allgulander, C; Ball, S; Erickson, J; Hartford, J; Raskin, J; Russell, J; Rynn, M | 1 |
| Aaronson, ST; Arnold, LM; Mallinckrodt, CH; Pigott, TA; Prakash, A; Wohlreich, MM | 1 |
| Florea, I; Gembert, K; Wade, A | 1 |
| Alexopoulos, GS; Bose, A; Gandhi, C; Gommoll, C; Khan, A; Li, D | 1 |
| D'Arrigo, T | 1 |
| Amore, M; Cazzolla, R; Mandrioli, R; Mercolini, L; Raggi, MA | 1 |
| Leventhal, L; Piesla, M; Wantuch, C | 1 |
| Callaghan, JT; Chappell, JC; Derby, MA; Ereshefsky, L; Gonzales, CR; Hoelscher, D; Leese, PT; Leibowitz, M; Mitchell, MI; Zhang, L | 1 |
| Frampton, JE; Plosker, GL | 1 |
| Bent, AE; Bump, RC; Gousse, AE; Hendrix, SL; Klutke, CG; Monga, AK; Muram, D; Yalcin, I; Yuen, CK | 1 |
| D'Souza, DN; Erickson, JS; Fava, M; Hartford, JT; Russell, JM; Weisberg, R | 1 |
| Kajdasz, DK; Raskin, J; Xu, JY | 1 |
| Iosifescu, DV; Raskin, J; Sheridan, M; Wiltse, CG; Wise, TN; Xu, JY | 1 |
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249 review(s) available for duloxetine hydrochloride and thiophenes
| Article | Year |
|---|---|
New approaches to the treatment of depression.
Topics: Antidepressive Agents, Second-Generation; Brain; Bupropion; Citalopram; Cyclohexanols; Depressive Disorder; Dopamine; Duloxetine Hydrochloride; Humans; Receptors, Dopamine; Receptors, GABA; Receptors, Neurotransmitter; Receptors, Serotonin; Serotonin; Thiophenes; Venlafaxine Hydrochloride | 1996 |
Duloxetine Eli Lilly & Co.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Clinical Trials as Topic; Contraindications; Depressive Disorder; Drugs, Investigational; Duloxetine Hydrochloride; Humans; Thiophenes; Urinary Incontinence | 2000 |
Somatic symptoms, depression, and antidepressant treatment.
Topics: Antidepressive Agents; Comorbidity; Depressive Disorder; Duloxetine Hydrochloride; Humans; Personality Inventory; Psychiatric Status Rating Scales; Psychometrics; Somatoform Disorders; Thiophenes; Treatment Outcome | 2002 |
Dual serotonin and noradrenaline uptake inhibitor class of antidepressants potential for greater efficacy or just hype?
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Cyclopropanes; Depressive Disorder; Duloxetine Hydrochloride; Humans; Milnacipran; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2002 |
Duloxetine Eli Lilly.
Topics: Animals; Antidepressive Agents; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Duloxetine Hydrochloride; Humans; Neurotransmitter Uptake Inhibitors; Structure-Activity Relationship; Thiophenes | 2002 |
Duloxetine pharmacology: profile of a dual monoamine modulator.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Brain; Clinical Trials as Topic; Depressive Disorder; Duloxetine Hydrochloride; Electrophysiology; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2002 |
New hope in the treatment of painful symptoms in depression.
Topics: Animals; Antidepressive Agents; Clinical Trials as Topic; Cyclohexanols; Cyclopropanes; Depressive Disorder; Duloxetine Hydrochloride; Humans; Milnacipran; Pain; Thiophenes; Venlafaxine Hydrochloride | 2003 |
Neural control of the urethra and development of pharmacotherapy for stress urinary incontinence.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Drug Design; Duloxetine Hydrochloride; Humans; Muscle, Smooth; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urethra; Urinary Incontinence, Stress | 2003 |
Physical symptoms of depression: unmet needs in special populations.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Age Factors; Antidepressive Agents; Child; Comorbidity; Cyclohexanols; Delivery of Health Care; Depressive Disorder; Diagnosis, Differential; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Poverty; Selective Serotonin Reuptake Inhibitors; Sex Factors; Thiophenes; Venlafaxine Hydrochloride | 2003 |
Duloxetine: a serotonin-noradrenaline re-uptake inhibitor for the treatment of stress urinary incontinence.
Topics: Adrenergic Uptake Inhibitors; Clinical Trials as Topic; Duloxetine Hydrochloride; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2003 |
Update on overactive bladder: pharmacologic approaches on the horizon.
Topics: Administration, Cutaneous; Administration, Intravesical; Administration, Oral; Adrenergic beta-3 Receptor Antagonists; Benzhydryl Compounds; Benzilates; Benzofurans; Botulinum Toxins; Cresols; Dosage Forms; Dose-Response Relationship, Drug; Drug Compounding; Drug Evaluation; Duloxetine Hydrochloride; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Pyrrolidines; Thiophenes; Tolterodine Tartrate; Treatment Outcome; Urinary Bladder Diseases; Urination Disorders | 2003 |
Serotonin and norepinephrine involvement in efferent pathways to the urethral rhabdosphincter: implications for treating stress urinary incontinence.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic Uptake Inhibitors; Duloxetine Hydrochloride; Female; Humans; Motor Neurons; Norepinephrine; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Reflex; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Urethra; Urinary Incontinence, Stress; Urination | 2003 |
Serotonergic modulation of bladder afferent pathways.
Topics: Adrenergic Uptake Inhibitors; Afferent Pathways; Animals; Brain Stem; Cats; Duloxetine Hydrochloride; Humans; Nerve Fibers; Neurons, Afferent; Posterior Horn Cells; Rats; Receptors, Serotonin; Reflex; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Urinary Bladder; Urination | 2003 |
Pharmacologic treatment of stress urinary incontinence: expectations for outcome.
Topics: Adolescent; Adrenergic Agents; Adrenergic Uptake Inhibitors; Adult; Aged; Drug Evaluation; Duloxetine Hydrochloride; Estrogens; Exercise Therapy; Female; Humans; Male; Middle Aged; Motor Neurons; Patient Satisfaction; Pelvic Floor; Quality of Life; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2003 |
Efficacy and tolerability of duloxetine, a novel dual reuptake inhibitor, in the treatment of major depressive disorder.
Topics: Adrenergic Uptake Inhibitors; Clinical Trials as Topic; Depressive Disorder; Duloxetine Hydrochloride; Humans; Multicenter Studies as Topic; Norepinephrine; Pain; Selective Serotonin Reuptake Inhibitors; Serotonin; Somatoform Disorders; Thiophenes; Treatment Outcome | 2003 |
Role of 5-HT receptors in treatment of overactive bladder.
Topics: Animals; Clinical Trials as Topic; Duloxetine Hydrochloride; Humans; Receptors, Serotonin; Reflex; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Thiophenes; Urinary Bladder; Urinary Bladder, Neurogenic; Urinary Incontinence | 2003 |
Pharmacological agents used for the treatment of stress urinary incontinence in women.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Antidepressive Agents, Tricyclic; Duloxetine Hydrochloride; Female; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2003 |
Innovations in pharmacotherapy for stress urinary incontinence.
Topics: Adrenergic Uptake Inhibitors; Animals; Duloxetine Hydrochloride; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2003 |
Physical symptoms comorbid with depression and the new antidepressant duloxetine.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Anxiety Disorders; Comorbidity; Depressive Disorder; Duloxetine Hydrochloride; Gastrointestinal Diseases; Humans; Mood Disorders; Norepinephrine; Pain; Psychophysiologic Disorders; Selective Serotonin Reuptake Inhibitors; Serotonin; Sleep Wake Disorders; Thiophenes; Treatment Outcome | 2003 |
Newer antidepressants: review of efficacy and safety of escitalopram and duloxetine.
Topics: Citalopram; Depressive Disorder; Double-Blind Method; Duloxetine Hydrochloride; Humans; Placebos; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2004 |
Metabolism of the newest antidepressants: comparisons with related predecessors.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Duloxetine Hydrochloride; Humans; Pyrimidines; Serotonin Receptor Agonists; Thiophenes | 2004 |
The effect of duloxetine on painful physical symptoms in depressed patients: do improvements in these symptoms result in higher remission rates?
Topics: Adult; Antidepressive Agents; Comorbidity; Depressive Disorder; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Multicenter Studies as Topic; Pain; Pain Measurement; Placebos; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Severity of Illness Index; Thiophenes; Treatment Outcome | 2004 |
Role of serotonin and noradrenaline in stress urinary incontinence.
Topics: Adrenergic Uptake Inhibitors; Central Nervous System; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Norepinephrine; Peripheral Nervous System; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Urinary Bladder; Urinary Incontinence, Stress; Urination | 2004 |
Duloxetine: an innovative approach for treating stress urinary incontinence.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Aged, 80 and over; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2004 |
Stress urinary incontinence in women.
Topics: Adrenergic Uptake Inhibitors; Behavior Therapy; Biofeedback, Psychology; Duloxetine Hydrochloride; Exercise Therapy; Female; Health Status; Humans; Imipramine; Nurse Practitioners; Nursing Assessment; Pelvic Floor; Pessaries; Primary Health Care; Prosthesis Implantation; Quality of Life; Risk Assessment; Risk Factors; Thiophenes; Urinary Incontinence, Stress; Urodynamics; Women's Health | 2004 |
[Update on medical treatment of female stress urinary incontinence].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Duloxetine Hydrochloride; Estrogens; Female; Humans; Imipramine; Muscle, Smooth; Receptors, Adrenergic, alpha; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urethra; Urinary Incontinence, Stress | 2004 |
Duloxetine: a new approach for treating stress urinary incontinence.
Topics: Adrenergic Uptake Inhibitors; Animals; Cats; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Disease Models, Animal; Duloxetine Hydrochloride; Female; Humans; Nausea; Quality of Life; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2004 |
Common pathways of depression and pain.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Brain; Chronic Disease; Cyclohexanols; Depressive Disorder; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Norepinephrine; Pain; Recurrence; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Venlafaxine Hydrochloride | 2004 |
Duloxetine: mechanism of action at the lower urinary tract and Onuf's nucleus.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depressive Disorder; Duloxetine Hydrochloride; Humans; Sacrococcygeal Region; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress; Urinary Tract | 2004 |
[Pharmaceutical treatment of stress incontinence. New approaches via a direct effect of duloxetine on Onuf's nucleus].
Topics: Animals; Clinical Trials as Topic; Duloxetine Hydrochloride; Humans; Motor Neurons; Presynaptic Terminals; Sacrococcygeal Region; Selective Serotonin Reuptake Inhibitors; Spinal Nerves; Thiophenes; Treatment Outcome; Urinary Bladder; Urinary Incontinence, Stress | 2004 |
Reboxetine: a norepinephrine selective reuptake pump inhibitor.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Biological Availability; Clinical Trials as Topic; Cyclopropanes; Depressive Disorder, Major; Drug Approval; Duloxetine Hydrochloride; Humans; Metabolic Clearance Rate; Milnacipran; Morpholines; Reboxetine; Thiazepines; Thiophenes; United States | 2004 |
[Duloxetine in the treatment of urinary incontinence in women].
Topics: Adrenergic Uptake Inhibitors; Duloxetine Hydrochloride; Female; Humans; Thiophenes; Treatment Outcome; Urinary Incontinence | 2004 |
Clinical experience with dual action antidepressants in different chronic pain syndromes.
Topics: Antidepressive Agents; Chronic Disease; Cyclohexanols; Cyclopropanes; Duloxetine Hydrochloride; Humans; Milnacipran; Pain; Thiophenes; Venlafaxine Hydrochloride | 2004 |
Can monoamine-based therapies be improved?
Topics: Adrenergic beta-Antagonists; Antidepressive Agents; Biogenic Monoamines; Cyclohexanols; Depressive Disorder; Drug Therapy, Combination; Duloxetine Hydrochloride; Humans; Receptors, Biogenic Amine; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2002 |
Balanced treatments for fibromyalgia.
Topics: Biogenic Monoamines; Depression; Duloxetine Hydrochloride; Fibromyalgia; Humans; Neurotransmitter Uptake Inhibitors; Pain Threshold; Thiophenes | 2004 |
Preview of new drugs for overactive bladder and incontinence: darifenacin, solifenacin, trospium, and duloxetine.
Topics: Benzilates; Benzofurans; Clinical Trials as Topic; Duloxetine Hydrochloride; Humans; Muscarinic Antagonists; Nortropanes; Pyrrolidines; Quinuclidines; Selective Serotonin Reuptake Inhibitors; Solifenacin Succinate; Tetrahydroisoquinolines; Thiophenes; Urinary Incontinence | 2004 |
Duloxetine: in stress urinary incontinence.
Topics: Adrenergic Uptake Inhibitors; Area Under Curve; Clinical Trials as Topic; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Metabolic Clearance Rate; Selective Serotonin Reuptake Inhibitors; Stress, Physiological; Thiophenes; Urinary Incontinence | 2004 |
Duloxetine: a dual reuptake inhibitor.
Topics: Adrenergic Uptake Inhibitors; Animals; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2004 |
[Urinary stress incontinence in women].
Topics: Adrenergic Uptake Inhibitors; Age Factors; Aged; Clinical Trials, Phase III as Topic; Duloxetine Hydrochloride; Exercise Therapy; Female; Humans; Middle Aged; Minimally Invasive Surgical Procedures; Pelvic Floor; Polypropylenes; Selective Serotonin Reuptake Inhibitors; Sex Factors; Surgical Mesh; Thiophenes; Urinary Bladder; Urinary Incontinence, Stress | 2004 |
Duloxetine: a new serotonin/noradrenaline reuptake inhibitor for the treatment of depression.
Topics: Adrenergic Uptake Inhibitors; Clinical Trials as Topic; Depressive Disorder; Duloxetine Hydrochloride; Humans; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2004 |
Duloxetine.
Topics: Antidepressive Agents; Depressive Disorder; Duloxetine Hydrochloride; Humans; Marketing; Thiophenes; United States | 2004 |
SNRIs in the management of acute major depressive disorder.
Topics: Acute Disease; Adrenergic Uptake Inhibitors; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cyclohexanols; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Placebos; Randomized Controlled Trials as Topic; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2004 |
Duloxetine in the treatment of Major Depressive Disorder: a comparison of efficacy in patients with and without melancholic features.
Topics: Adult; Cohort Studies; Comorbidity; Depressive Disorder; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Multicenter Studies as Topic; Placebos; Randomized Controlled Trials as Topic; Severity of Illness Index; Thiophenes; Treatment Outcome | 2005 |
[New options in pharmacological treatment of urinary stress incontinence in women].
Topics: Adrenergic Uptake Inhibitors; Dopamine Uptake Inhibitors; Duloxetine Hydrochloride; Female; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2004 |
2004 drug approval highlights: FDA update.
Topics: Administration, Cutaneous; Amlodipine; Anti-Bacterial Agents; Antidepressive Agents; Bronchodilator Agents; Cardiovascular Agents; Drug Approval; Drug Combinations; Duloxetine Hydrochloride; Eplerenone; Estradiol; Excitatory Amino Acid Antagonists; Female; Gastrointestinal Agents; Heptanoic Acids; Humans; Ketolides; Male; Memantine; Osteoporosis, Postmenopausal; Pyrroles; Rifamycins; Rifaximin; Scopolamine Derivatives; Spironolactone; Thiophenes; Tiotropium Bromide; United States | 2005 |
Cardiovascular profile of duloxetine, a dual reuptake inhibitor of serotonin and norepinephrine.
Topics: Adult; Blood Pressure; Duloxetine Hydrochloride; Female; Heart Rate; Humans; Male; Middle Aged; Norepinephrine; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2005 |
Efficacy, safety and tolerability of duloxetine 60 mg once daily in major depression.
Topics: Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Administration Schedule; Duloxetine Hydrochloride; Humans; Placebos; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2005 |
[Review of antidepressants from the TCAs to the third generation drugs].
Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Cyclohexanols; Cyclopropanes; Depressive Disorder, Major; Drug Combinations; Duloxetine Hydrochloride; Humans; Mianserin; Milnacipran; Mirtazapine; Monoamine Oxidase Inhibitors; Morpholines; Piperazines; Pyrimidines; Reboxetine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Trazodone; Triazoles; Venlafaxine Hydrochloride | 2004 |
Duloxetine: a dual serotonin-norepinephrine reuptake inhibitor for treatment of major depressive disorder.
Topics: Adolescent; Adult; Aged; Depressive Disorder, Major; Drug Interactions; Duloxetine Hydrochloride; Humans; Middle Aged; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2005 |
The dual transporter inhibitor duloxetine: a review of its preclinical pharmacology, pharmacokinetic profile, and clinical results in depression.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Depression; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Microdialysis; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2005 |
Safety and tolerability of duloxetine in the treatment of major depressive disorder: analysis of pooled data from eight placebo-controlled clinical trials.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Body Weight; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Placebos; Randomized Controlled Trials as Topic; Sexual Behavior; Thiophenes | 2005 |
Pharmacotherapy for stress urinary incontinence.
Topics: Adrenergic Agonists; Duloxetine Hydrochloride; Estrogen Replacement Therapy; Female; Humans; Quality of Life; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urethra; Urinary Incontinence, Stress; Urination | 2005 |
Duloxetine: pharmacoeconomic implications of an antidepressant that alleviates painful physical symptoms.
Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Economics, Pharmaceutical; Humans; Pain; Pain Measurement; Thiophenes | 2005 |
Is treatment-associated hypomania rare with duloxetine: secondary analysis of controlled trials in non-bipolar depression.
Topics: Adult; Bipolar Disorder; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Placebos; Randomized Controlled Trials as Topic; Reproducibility of Results; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2005 |
Serotonin and noradrenaline reuptake inhibitors (SNRI) for stress urinary incontinence in adults.
Topics: Adrenergic Uptake Inhibitors; Adult; Duloxetine Hydrochloride; Humans; Norepinephrine; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2005 |
Time course of depression-symptom improvement during treatment with duloxetine.
Topics: Adult; Antidepressive Agents; Back Pain; Depressive Disorder, Major; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Follow-Up Studies; Gastrointestinal Diseases; Guilt; Humans; Hypochondriasis; Male; Pain Measurement; Randomized Controlled Trials as Topic; Remission Induction; Sexual Dysfunctions, Psychological; Shoulder Pain; Sleep Initiation and Maintenance Disorders; Somatoform Disorders; Surveys and Questionnaires; Thiophenes; Time Factors | 2005 |
Cost effectiveness of duloxetine compared with venlafaxine-XR in the treatment of major depressive disorder.
Topics: Adolescent; Adult; Cost of Illness; Cost-Benefit Analysis; Cyclohexanols; Decision Trees; Depressive Disorder, Major; Duloxetine Hydrochloride; Economics, Pharmaceutical; Health Care Costs; Humans; Middle Aged; Models, Econometric; Norepinephrine; Ontario; Outpatients; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2005 |
Duloxetine for management of stress urinary incontinence.
Topics: Adrenergic Uptake Inhibitors; Animals; Biotransformation; Clinical Trials as Topic; Drug Interactions; Duloxetine Hydrochloride; Humans; Rats; Thiophenes; Urinary Incontinence, Stress | 2005 |
SNRIs: their pharmacology, clinical efficacy, and tolerability in comparison with other classes of antidepressants.
Topics: Antidepressive Agents; Cyclohexanols; Cyclopropanes; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; In Vitro Techniques; Milnacipran; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Venlafaxine Hydrochloride; Vesicular Monoamine Transport Proteins | 2005 |
Duloxetine and venlafaxine-XR in the treatment of major depressive disorder: a meta-analysis of randomized clinical trials.
Topics: Adult; Cyclohexanols; Data Collection; Delayed-Action Preparations; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Patient Dropouts; Randomized Controlled Trials as Topic; Review Literature as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2005 |
Duloxetine hydrochloride: a new dual-acting medication for the treatment of major depressive disorder.
Topics: Adult; Aged; Antidepressive Agents; Biological Availability; Depressive Disorder, Major; Drug Interactions; Duloxetine Hydrochloride; Female; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Multicenter Studies as Topic; Nausea; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2005 |
[Pharmacotherapy of stress incontinence].
Topics: Adrenergic Agents; Antidepressive Agents; Duloxetine Hydrochloride; Estrogens; Female; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2005 |
Neurobiology of stress urinary incontinence: new insights and implications for treatment.
Topics: Adrenergic Uptake Inhibitors; Duloxetine Hydrochloride; Female; Genitalia, Female; Gynecology; Humans; Selective Serotonin Reuptake Inhibitors; Synaptic Transmission; Thiophenes; Urethra; Urinary Incontinence, Stress | 2005 |
Safety and adverse event profile of duloxetine.
Topics: Cytochrome P-450 Enzyme System; Depressive Disorder, Major; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Interactions; Duloxetine Hydrochloride; Half-Life; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2005 |
Symptoms following abrupt discontinuation of duloxetine treatment in patients with major depressive disorder.
Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Long-Term Care; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; Thiophenes | 2005 |
Duloxetine for the treatment of major depressive disorder: a closer look at efficacy and safety data across the approved dose range.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2006 |
Duloxetine: a balanced and selective norepinephrine- and serotonin-reuptake inhibitor.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Area Under Curve; Depressive Disorder; Diabetic Neuropathies; Drug Interactions; Duloxetine Hydrochloride; Formularies as Topic; Humans; Liver Failure; Randomized Controlled Trials as Topic; Renal Insufficiency; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence | 2005 |
[Treatment of urinary incontinence in the elderly woman].
Topics: Age Factors; Aged; Algorithms; Antidepressive Agents; Duloxetine Hydrochloride; Female; Humans; Muscarinic Antagonists; Quality of Life; Sex Factors; Thiophenes; Urinary Incontinence; Urinary Incontinence, Stress | 2005 |
Duloxetine in diabetic neuropathy.
Topics: Diabetic Neuropathies; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2006 |
[Place of duloxetine in the treatment of stress urinary incontinence].
Topics: Clinical Trials as Topic; Duloxetine Hydrochloride; Female; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2005 |
Duloxetine: a new selective and dual-acting antidepressant.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Depression; Drug Evaluation, Preclinical; Duloxetine Hydrochloride; Humans; Pain; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2006 |
Duloxetine for male stress incontinence.
Topics: Animals; Clinical Trials as Topic; Duloxetine Hydrochloride; Humans; Male; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2006 |
What do we know about duloxetine's mode of action? Evidence from animals to humans.
Topics: Adrenergic Uptake Inhibitors; Animals; Duloxetine Hydrochloride; Female; Humans; Models, Animal; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urethra; Urinary Incontinence, Stress | 2006 |
Initial management of stress urinary incontinence: pelvic floor muscle training and duloxetine.
Topics: Adrenergic Uptake Inhibitors; Combined Modality Therapy; Duloxetine Hydrochloride; Exercise Therapy; Female; Humans; Pelvic Floor; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2006 |
Duloxetine in women awaiting surgery.
Topics: Adrenergic Uptake Inhibitors; Duloxetine Hydrochloride; Female; Humans; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress; Waiting Lists | 2006 |
Safety and tolerability of duloxetine in women with stress urinary incontinence.
Topics: Adrenergic Uptake Inhibitors; Cardiovascular Diseases; Central Nervous System Diseases; Drug Interactions; Duloxetine Hydrochloride; Female; Female Urogenital Diseases; Humans; Nausea; Selective Serotonin Reuptake Inhibitors; Suicide; Thiophenes; Urinary Incontinence, Stress | 2006 |
Duloxetine in the treatment of major depressive disorder: comparisons of safety and efficacy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Black or African American; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes; Treatment Outcome; White People | 2006 |
Stress incontinence.
Topics: Colposcopy; Duloxetine Hydrochloride; Electric Stimulation Therapy; Exercise Therapy; Female; Humans; Pelvic Floor; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2005 |
Serotonin-norepinephrine reuptake inhibitors in the treatment of obsessive-compulsive disorder: A critical review.
Topics: Adrenergic Uptake Inhibitors; Clomipramine; Controlled Clinical Trials as Topic; Cyclohexanols; Double-Blind Method; Drug Resistance; Duloxetine Hydrochloride; Humans; Meta-Analysis as Topic; Obsessive-Compulsive Disorder; Placebos; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2006 |
Prospects for the treatment of depression.
Topics: Acetamides; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Hypnotics and Sedatives; Nerve Growth Factors; Selective Serotonin Reuptake Inhibitors; Substance P; Thiophenes; Vasopressins | 2006 |
Duloxetine in the treatment of major depressive disorder: comparisons of safety and tolerability in male and female patients.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Meta-Analysis as Topic; Middle Aged; Multicenter Studies as Topic; Patient Dropouts; Randomized Controlled Trials as Topic; Sex Factors; Thiophenes | 2006 |
Duloxetine efficacy for major depressive disorder in male vs. female patients: data from 7 randomized, double-blind, placebo-controlled trials.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Health Status; Humans; Male; Middle Aged; Multicenter Studies as Topic; Pain Measurement; Placebos; Psychiatric Status Rating Scales; Quality of Life; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Sex Factors; Surveys and Questionnaires; Thiophenes; Treatment Outcome | 2006 |
Duloxetine compared with fluoxetine and venlafaxine: use of meta-regression analysis for indirect comparisons.
Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Cyclohexanols; Depressive Disorder, Major; Duloxetine Hydrochloride; Fluoxetine; Humans; Randomized Controlled Trials as Topic; Regression Analysis; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2006 |
Dose-response relationship of duloxetine in placebo-controlled clinical trials in patients with major depressive disorder.
Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Depressive Disorder; Diagnostic and Statistical Manual of Mental Disorders; Dose-Response Relationship, Drug; Drug Administration Schedule; Duloxetine Hydrochloride; Europe; Female; Humans; Male; Middle Aged; Paroxetine; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; United States | 2006 |
Clinically relevant pharmacology of neuropsychiatric drugs approved over the last three years: Part II.
Topics: Anti-HIV Agents; Antidepressive Agents; Antiparkinson Agents; Apomorphine; Atazanavir Sulfate; Azabicyclo Compounds; Carbamates; Central Nervous System Agents; Cytochrome P-450 Enzyme System; Drug Approval; Drug Interactions; Duloxetine Hydrochloride; Furans; Humans; Hypnotics and Sedatives; Indenes; Long QT Syndrome; Mental Disorders; Oligopeptides; Organophosphates; Piperazines; Psychopharmacology; Pyridines; Sulfonamides; Thiophenes | 2006 |
Efficacy of duloxetine in painful symptoms: an analgesic or antidepressant effect?
Topics: Analgesics; Antidepressive Agents; Chronic Disease; Depressive Disorder; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Pain; Thiophenes; Treatment Outcome | 2006 |
Duloxetine, a serotonin and noradrenaline reuptake inhibitor (SNRI) for the treatment of stress urinary incontinence: a systematic review.
Topics: Adrenergic Uptake Inhibitors; Duloxetine Hydrochloride; Female; Humans; Quality of Life; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2007 |
Duloxetine in the treatment of major depressive disorder: comparisons of safety and efficacy in U.S. Hispanic and majority Caucasian patients.
Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Hispanic or Latino; Humans; Multicenter Studies as Topic; Patient Dropouts; Placebos; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Severity of Illness Index; Thiophenes; Treatment Outcome; White People | 2006 |
Duloxetine: meta-analyses of suicidal behaviors and ideation in clinical trials for major depressive disorder.
Topics: Adult; Antidepressive Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Incidence; Male; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Suicide; Thinking; Thiophenes; Time Factors | 2006 |
[Dual acting reuptake inhibitors in the treatment of depression and pain].
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Chronic Disease; Depression; Diabetes Complications; Diabetes Mellitus, Type 2; Duloxetine Hydrochloride; Humans; Norepinephrine; Pain; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Treatment Outcome | 2006 |
[Duloxetine, a new therapeutic option for diabetic peripheral neuropathic pain].
Topics: Adrenergic Uptake Inhibitors; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Pain; Quality of Life; Risk Factors; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2006 |
[Medication of the month. Duloxetine (Cymbalta)].
Topics: Antidepressive Agents; Depression; Duloxetine Hydrochloride; Humans; Thiophenes | 2006 |
The application of evidence-based principles of care in older persons (issue 6): urinary incontinence.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Aged; Algorithms; Chronic Disease; Cost of Illness; Decision Trees; Drug Monitoring; Duloxetine Hydrochloride; Ephedrine; Evidence-Based Medicine; Exercise Therapy; Geriatric Assessment; Geriatrics; Humans; Muscarinic Antagonists; Pelvic Floor; Practice Guidelines as Topic; Receptors, Adrenergic, alpha-1; Referral and Consultation; Research Design; Risk Factors; Thiophenes; Toilet Training; Treatment Outcome; Urinary Incontinence; Urodynamics | 2007 |
New developments in the treatment of urinary incontinence.
Topics: Administration, Cutaneous; Adrenergic Uptake Inhibitors; Benzofurans; Drug Therapy, Combination; Duloxetine Hydrochloride; Humans; Mandelic Acids; Muscarinic Antagonists; Pyrrolidines; Quality of Life; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Thiophenes; Treatment Outcome; Urinary Bladder, Overactive; Urinary Incontinence, Stress | 2006 |
Treatment options for patients with suboptimal response to surgery for stress urinary incontinence.
Topics: Adrenergic Antagonists; Antidepressive Agents, Tricyclic; Biofeedback, Psychology; Case Management; Collagen; Duloxetine Hydrochloride; Estrogen Replacement Therapy; Exercise Therapy; Female; Humans; Injections; Pessaries; Postoperative Complications; Prostheses and Implants; Quality of Life; Radiofrequency Therapy; Reoperation; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2007 |
[Conservative treatment of male stress incontinence].
Topics: Duloxetine Hydrochloride; Electric Stimulation Therapy; Germany; Humans; Male; Physical Therapy Modalities; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prostatectomy; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2007 |
[Psychiatry].
Topics: Adolescent; Antidepressive Agents; Bipolar Disorder; Child; Depression; Duloxetine Hydrochloride; Humans; Mental Disorders; Schizophrenia; Thiophenes | 2007 |
An independent meta-analysis using summary data for clinical response, remission, and discontinuation for any reason from the 6 pivotal phase III randomized clinical trials of duloxetine in major depressive disorder.
Topics: Antidepressive Agents, Second-Generation; Clinical Trials, Phase III as Topic; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Paroxetine; Randomized Controlled Trials as Topic; Remission Induction; Thiophenes; Treatment Outcome; Withholding Treatment | 2007 |
Is there a place for duloxetine?
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depressive Disorder; Diabetic Neuropathies; Drug Costs; Drug Interactions; Duloxetine Hydrochloride; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2007 |
An evaluation of the cardiovascular safety profile of duloxetine: findings from 42 placebo-controlled studies.
Topics: Adrenergic Uptake Inhibitors; Anxiety Disorders; Cardiovascular Diseases; Depressive Disorder, Major; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Placebos; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence | 2007 |
Update on pharmacotherapy guidelines for treatment of neuropathic pain.
Topics: Analgesics; Animals; Cannabidiol; Chronic Disease; Dronabinol; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Guidelines as Topic; Humans; Pain; Peripheral Nervous System Diseases; Pregabalin; Thiophenes | 2007 |
Burning mouth syndrome: will better understanding yield better management?
Topics: Antidepressive Agents; Burning Mouth Syndrome; Duloxetine Hydrochloride; Humans; Mexiletine; Thiophenes | 2007 |
Pharmacotherapy of generalized anxiety disorder: results of duloxetine treatment from a pooled analysis of three clinical trials.
Topics: Adult; Antidepressive Agents; Anxiety Disorders; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Placebos; Randomized Controlled Trials as Topic; Severity of Illness Index; Statistics as Topic; Thiophenes; Treatment Outcome | 2007 |
Duloxetine: a review of its use in the treatment of major depressive disorder.
Topics: Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Interactions; Duloxetine Hydrochloride; Humans; Randomized Controlled Trials as Topic; Thiophenes | 2007 |
Efficacy of duloxetine in the treatment of generalized anxiety disorder in patients with clinically significant pain symptoms.
Topics: Adult; Antidepressive Agents; Anxiety Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Pain; Pain Measurement; Personality Inventory; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2008 |
Diabetic neuropathy: new strategies for treatment.
Topics: Aldehyde Reductase; Amines; Analgesics; Anticonvulsants; Antidepressive Agents; Antioxidants; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Thiamine; Thioctic Acid; Thiophenes | 2008 |
[Stress urinary incontinence in women--current treatment alternatives].
Topics: Adrenergic Uptake Inhibitors; Duloxetine Hydrochloride; Electric Stimulation Therapy; Exercise Therapy; Female; Humans; Incontinence Pads; Pelvic Floor; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress; Urination | 2007 |
Serotonin and noradrenaline involvement in urinary incontinence, depression and pain: scientific basis for overlapping clinical efficacy from a single drug, duloxetine.
Topics: Antidepressive Agents; Depressive Disorder, Major; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Humans; Male; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2007 |
Patterns of depressive symptom response in duloxetine-treated outpatients with mild, moderate or more severe depression.
Topics: Adult; Aged; Antidepressive Agents; Cohort Studies; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Severity of Illness Index; Thiophenes; Treatment Outcome | 2007 |
Diabetic peripheral neuropathic pain: recognition and management.
Topics: Antidepressive Agents; Diabetic Foot; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Pain; Thiophenes | 2007 |
Assessing the impact of pharmacologic intervention on the quality of life in diabetic peripheral neuropathic pain and fibromyalgia.
Topics: Antidepressive Agents; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Pain; Pregabalin; Quality of Life; Randomized Controlled Trials as Topic; Thiophenes | 2007 |
Safety profile of treatment in diabetic peripheral neuropathic pain.
Topics: Administration, Topical; Analgesics; Anesthetics, Local; Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Capsaicin; Cyclohexanols; Diabetic Neuropathies; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Humans; Pain; Pregabalin; Thiophenes; Venlafaxine Hydrochloride | 2007 |
Duloxetine and other antidepressants in the treatment of patients with fibromyalgia.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Antidepressive Agents, Tricyclic; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Monoamine Oxidase Inhibitors; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Sex Characteristics; Thiophenes; Treatment Outcome | 2007 |
An overview of stress urinary incontinence treatment in women.
Topics: Duloxetine Hydrochloride; Electric Stimulation; Female; Humans; Muscle Strength; Pelvic Floor; Selective Serotonin Reuptake Inhibitors; Suburethral Slings; Thiophenes; Urinary Incontinence, Stress | 2007 |
Evidence for the efficacy of duloxetine in treating mild, moderate, and severe depression.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Retrospective Studies; Severity of Illness Index; Thiophenes; Treatment Outcome | 2007 |
Duloxetine for the treatment of fibromyalgia in women: pooled results from two randomized, placebo-controlled clinical trials.
Topics: Adult; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Middle Aged; Neurotransmitter Uptake Inhibitors; Pain Measurement; Placebo Effect; Quality of Life; Severity of Illness Index; Thiophenes; Treatment Outcome; Women's Health | 2007 |
Efficacy of duloxetine and selective serotonin reuptake inhibitors: comparisons as assessed by remission rates in patients with major depressive disorder.
Topics: Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Fluoxetine; Humans; Paroxetine; Placebos; Randomized Controlled Trials as Topic; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2007 |
Mixed urinary incontinence: continuing to confound?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Benzhydryl Compounds; Combined Modality Therapy; Cresols; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Muscarinic Antagonists; Phenylpropanolamine; Quality of Life; Severity of Illness Index; Thiophenes; Tolterodine Tartrate; Treatment Outcome; Urinary Incontinence; Urodynamics; Urologic Surgical Procedures | 2007 |
[Conservative treatment of urinary incontinence].
Topics: Duloxetine Hydrochloride; Electric Stimulation; Estrogens; Female; Humans; Pelvic Floor; Physical Therapy Modalities; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence; Urinary Incontinence, Stress; Urinary Incontinence, Urge | 2007 |
Duloxetine does not relieve painful physical symptoms in depression: a meta-analysis.
Topics: Adult; Analgesics; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Duloxetine Hydrochloride; Humans; Pain; Pain Measurement; Paroxetine; Psychophysiologic Disorders; Randomized Controlled Trials as Topic; Somatoform Disorders; Thiophenes; Treatment Outcome | 2008 |
Review of duloxetine in the management of diabetic peripheral neuropathic pain.
Topics: Clinical Trials as Topic; Diabetic Neuropathies; Drug Interactions; Duloxetine Hydrochloride; Humans; Molecular Structure; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2007 |
Examining quality of life in patients with generalized anxiety disorder: clinical relevance and response to duloxetine treatment.
Topics: Anxiety Disorders; Diagnostic and Statistical Manual of Mental Disorders; Disability Evaluation; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Endpoint Determination; Female; Humans; Male; Multicenter Studies as Topic; Neurotransmitter Uptake Inhibitors; Placebos; Psychiatric Status Rating Scales; Quality of Life; Randomized Controlled Trials as Topic; Severity of Illness Index; Thiophenes; Treatment Outcome | 2008 |
Systematic review: randomized, controlled trials of nonsurgical treatments for urinary incontinence in women.
Topics: Benzhydryl Compounds; Cholinergic Antagonists; Collagen; Cresols; Duloxetine Hydrochloride; Electric Stimulation Therapy; Estrogen Replacement Therapy; Exercise Therapy; Female; Humans; Magnetics; Mandelic Acids; Pelvic Floor; Pessaries; Phenylpropanolamine; Randomized Controlled Trials as Topic; Thiophenes; Tolterodine Tartrate; Urinary Incontinence | 2008 |
Nonsurgical treatment of stress urinary incontinence (SUI): grading of evidence in systematic reviews.
Topics: Biofeedback, Psychology; Duloxetine Hydrochloride; Electric Stimulation Therapy; Estrogens; Exercise Therapy; Humans; Randomized Controlled Trials as Topic; Review Literature as Topic; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2008 |
Clinical practice. Urinary stress incontinence in women.
Topics: Duloxetine Hydrochloride; Female; Humans; Intrauterine Devices; Middle Aged; Physical Therapy Modalities; Practice Guidelines as Topic; Risk Factors; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2008 |
The hepatic safety profile of duloxetine: a review.
Topics: Alanine Transaminase; Antidepressive Agents; Aspartate Aminotransferases; Duloxetine Hydrochloride; Humans; Liver; Thiophenes | 2008 |
The treatment of urinary incontinence with Duloxetine.
Topics: Adrenergic Uptake Inhibitors; Duloxetine Hydrochloride; Female; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2008 |
Clinical evidence for serotonin and norepinephrine reuptake inhibition of duloxetine.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depression; Duloxetine Hydrochloride; Evidence-Based Medicine; Humans; Norepinephrine Plasma Membrane Transport Proteins; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2008 |
Duloxetine in the treatment of major psychiatric and neuropathic disorders.
Topics: Antidepressive Agents; Anxiety; Clinical Trials as Topic; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Pain; Peripheral Nervous System Diseases; Practice Patterns, Physicians'; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2008 |
Compelling or irrelevant? Using number needed to treat can help decide.
Topics: Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Data Interpretation, Statistical; Depressive Disorder, Major; Dibenzothiazepines; Duloxetine Hydrochloride; Evidence-Based Medicine; Humans; Outcome Assessment, Health Care; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Schizophrenia; Secondary Prevention; Thiophenes; Treatment Outcome | 2008 |
[Antidepressants and their onset of action: a major clinical, methodological and pronostical issue].
Topics: Affect; Antidepressive Agents; Citalopram; Cyclohexanols; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Mianserin; Mirtazapine; Patient Satisfaction; Personality Inventory; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Suicide Prevention; Thiophenes; Time Factors; Treatment Refusal; Venlafaxine Hydrochloride | 2008 |
Escitalopram and duloxetine in the treatment of major depressive disorder: a pooled analysis of two trials.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2008 |
Answers to the most common questions about the hepatic safety profile of duloxetine.
Topics: Antidepressive Agents; Chemical and Drug Induced Liver Injury; Depressive Disorder; Drug Approval; Drug Labeling; Duloxetine Hydrochloride; Humans; Liver Diseases; Risk Assessment; Thiophenes; United States | 2008 |
Practical management strategies for the chronic pain patient.
Topics: Administration, Cutaneous; Amines; Analgesics; Antidepressive Agents, Tricyclic; Carbamazepine; Chronic Disease; Clinical Protocols; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Monitoring; Drug Tolerance; Duloxetine Hydrochloride; Family Practice; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Middle Aged; Pain; Practice Guidelines as Topic; Pregabalin; Randomized Controlled Trials as Topic; Substance-Related Disorders; Thiophenes; Treatment Outcome | 2007 |
Duloxetine for painful diabetic neuropathy and fibromyalgia pain: systematic review of randomised trials.
Topics: Adrenergic Uptake Inhibitors; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Pain; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2008 |
Tolerability of amine uptake inhibitors in urologic diseases.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Cyclohexanols; Duloxetine Hydrochloride; Humans; Meta-Analysis as Topic; Norepinephrine; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urologic Diseases; Venlafaxine Hydrochloride | 2006 |
Hepatic effects of duloxetine-I: non-clinical and clinical trial data.
Topics: Adrenergic Uptake Inhibitors; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Biomarkers; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Consumer Product Safety; Drug Evaluation, Preclinical; Duloxetine Hydrochloride; Humans; Liver; Liver Diseases; Risk Assessment; Risk Factors; Selective Serotonin Reuptake Inhibitors; Species Specificity; Thiophenes | 2008 |
Hepatic effects of duloxetine-II: spontaneous reports and epidemiology of hepatic events.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Adverse Drug Reaction Reporting Systems; Age Distribution; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Child; Consumer Product Safety; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Liver; Liver Diseases; Male; Middle Aged; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Sex Distribution; Thiophenes; Young Adult | 2008 |
Duloxetine for neuropathic pain based on recent clinical trials.
Topics: Antidepressive Agents; Clinical Trials as Topic; Duloxetine Hydrochloride; Humans; Neuralgia; Thiophenes; Treatment Outcome | 2006 |
The relationship between antidepressant and analgesic responses: findings from six placebo-controlled trials assessing the efficacy of duloxetine in patients with major depressive disorder.
Topics: Adult; Analgesia; Analgesics; Antidepressive Agents; Clinical Trials, Phase III as Topic; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Pain; Placebos; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2008 |
Efficacy, tolerability, and safety of duloxetine.
Topics: Antidepressive Agents, Second-Generation; Depressive Disorder; Duloxetine Hydrochloride; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2005 |
Clinical impact of duloxetine treatment on sleep in patients with major depressive disorder.
Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Sleep; Sleep Wake Disorders; Thiophenes; Treatment Outcome | 2008 |
Effect of desvenlafaxine on the cytochrome P450 2D6 enzyme system.
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Cyclohexanols; Cytochrome P-450 CYP2D6; Depressive Disorder, Major; Desipramine; Desvenlafaxine Succinate; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Health Status; Humans; Paroxetine; Thiophenes | 2008 |
Central sensitisation phenomena in primary headaches: overview of a preventive therapeutic approach.
Topics: Animals; Duloxetine Hydrochloride; Fibromyalgia; Headache; Humans; Migraine Disorders; Pain; Pain Management; Sleep Deprivation; Thiophenes | 2008 |
Duloxetine for the treatment of fibromyalgia.
Topics: Antidepressive Agents; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Duloxetine Hydrochloride; Fibromyalgia; Humans; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Thiophenes | 2008 |
[Is medical therapy useful in the management of stress urinary incontinence?].
Topics: Duloxetine Hydrochloride; Female; Humans; Male; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2009 |
Meta-analysis of duloxetine vs. pregabalin and gabapentin in the treatment of diabetic peripheral neuropathic pain.
Topics: Amines; Analgesics; Analysis of Variance; Bayes Theorem; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Peripheral Nervous System; Pregabalin; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2009 |
Duloxetine in the treatment of generalized anxiety disorder.
Topics: Adrenergic Uptake Inhibitors; Anxiety Disorders; Clinical Trials as Topic; Duloxetine Hydrochloride; Humans; Thiophenes | 2009 |
Duloxetine in acute major depression: review of comparisons to placebo and standard antidepressants using dissimilar methods.
Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Placebos; Randomized Controlled Trials as Topic; Thiophenes | 2009 |
When worlds collide: urinary incontinence and female sexuality.
Topics: Attitude to Health; Coitus; Duloxetine Hydrochloride; Dyspareunia; Electric Stimulation Therapy; Exercise Therapy; Female; Humans; Nurse's Role; Patient Education as Topic; Pelvic Floor; Pessaries; Referral and Consultation; Selective Serotonin Reuptake Inhibitors; Self Concept; Sexual Partners; Suburethral Slings; Thiophenes; Urinary Incontinence | 2009 |
Duloxetine in the management of elderly patients with major depressive disorder: an analysis of published data.
Topics: Age Factors; Aged; Animals; Controlled Clinical Trials as Topic; Depressive Disorder, Major; Disease Management; Duloxetine Hydrochloride; Humans; Thiophenes | 2009 |
Population pharmacokinetics of orally administered duloxetine in patients: implications for dosing recommendation.
Topics: Administration, Oral; Adult; Age Factors; Area Under Curve; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Hispanic or Latino; Humans; Male; Middle Aged; Racial Groups; Selective Serotonin Reuptake Inhibitors; Sex Factors; Smoking; Thiophenes | 2009 |
[Severe forms of depression: the efficacy of escitalopram].
Topics: Antidepressive Agents, Second-Generation; Citalopram; Clinical Trials as Topic; Cyclohexanols; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Follow-Up Studies; Humans; Paroxetine; Personality Inventory; Psychometrics; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2009 |
Quality of life measurement in antidepressant trials. Is there an added value?
Topics: Activities of Daily Living; Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Depressive Disorder; Duloxetine Hydrochloride; Humans; Personality Inventory; Psychometrics; Quality of Life; Randomized Controlled Trials as Topic; Reproducibility of Results; Thiophenes | 2009 |
Duloxetine: a review of its use in the treatment of generalized anxiety disorder.
Topics: Antidepressive Agents; Anxiety Disorders; Databases, Bibliographic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Duloxetine Hydrochloride; Humans; Meta-Analysis as Topic; Thiophenes; Treatment Outcome | 2009 |
Update on duloxetine for the management of stress urinary incontinence.
Topics: Depression; Duloxetine Hydrochloride; Female; Humans; Nervous System; Selective Serotonin Reuptake Inhibitors; Thiophenes; United Kingdom; Urinary Bladder, Overactive; Urinary Incontinence, Stress; Urinary Tract | 2009 |
Safety and tolerability of duloxetine in the treatment of patients with fibromyalgia: pooled analysis of data from five clinical trials.
Topics: Antidepressive Agents; Duloxetine Hydrochloride; Fibromyalgia; Humans; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2009 |
Duloxetine: in patients with fibromyalgia.
Topics: Adrenergic Uptake Inhibitors; Clinical Trials, Phase III as Topic; Duloxetine Hydrochloride; Fibromyalgia; Pain Measurement; Thiophenes; Treatment Outcome | 2009 |
Psychogenic tremor in a patient with a major depressive episode.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Cognitive Behavioral Therapy; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Hospitalization; Humans; Olanzapine; Psychophysiologic Disorders; Thiophenes; Tremor | 2009 |
[Mechanism of action of new generation antidepressants under development in Japan: focusing on dopamine neurotransmission].
Topics: Antidepressive Agents; Citalopram; Dopamine; Duloxetine Hydrochloride; Humans; Japan; Mianserin; Mirtazapine; Synaptic Transmission; Thiophenes | 2009 |
Escitalopram versus SNRI antidepressants in the acute treatment of major depressive disorder: integrative analysis of four double-blind, randomized clinical trials.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Citalopram; Cyclohexanols; Depressive Disorder, Major; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Time Factors; Venlafaxine Hydrochloride; Young Adult | 2009 |
Medical management of stress urinary incontinence: is there a future?
Topics: Adrenergic Antagonists; Clinical Trials as Topic; Duloxetine Hydrochloride; Female; Forecasting; Hormone Replacement Therapy; Humans; Male; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2009 |
Current progress in the pharmacological therapy of fibromyalgia.
Topics: Adrenergic Uptake Inhibitors; Analgesics; Animals; Clinical Trials as Topic; Cyclopropanes; Drugs, Investigational; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Milnacipran; Pregabalin; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2009 |
Duloxetine for treating painful neuropathy or chronic pain.
Topics: Analgesics; Chronic Disease; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Randomized Controlled Trials as Topic; Thiophenes | 2009 |
The general and comparative efficacy and safety of duloxetine in major depressive disorder: a systematic review and meta-analysis.
Topics: Antidepressive Agents; Body Weight; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Nausea; Randomized Controlled Trials as Topic; Serotonin Syndrome; Thiophenes | 2009 |
[Pharmacological treatment for stress urinary incontinence in prostate cancer].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic Uptake Inhibitors; Duloxetine Hydrochloride; Humans; Imipramine; Male; Prostatectomy; Prostatic Neoplasms; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2009 |
New drug treatments for urinary incontinence.
Topics: Antidepressive Agents; Antidiuretic Agents; Antimutagenic Agents; Duloxetine Hydrochloride; Estrogens; Female; Humans; Practice Guidelines as Topic; Thiophenes; Urinary Bladder, Overactive; Urinary Incontinence | 2010 |
A treatment algorithm for neuropathic pain: an update.
Topics: Algorithms; Analgesics; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain Measurement; Paroxetine; Pregabalin; Randomized Controlled Trials as Topic; Thiophenes | 2009 |
Escitalopram versus serotonin noradrenaline reuptake inhibitors as second step treatment for patients with major depressive disorder: a pooled analysis.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Citalopram; Cyclohexanols; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Norepinephrine; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride; Young Adult | 2010 |
Continuation treatment of major depressive disorder: is there a case for duloxetine?
Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Thiophenes | 2010 |
Adverse events, toxicity and post-mortem data on duloxetine: case reports and literature survey.
Topics: Accidents; Adult; Aged; Analgesics, Opioid; Biological Availability; Coroners and Medical Examiners; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Fentanyl; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Suicide; Tandem Mass Spectrometry; Thiophenes | 2010 |
Use of duloxetine in patients with an anxiety disorder, or with comorbid anxiety and major depressive disorder: a review of the literature.
Topics: Animals; Antidepressive Agents; Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Quality of Life; Thiophenes | 2010 |
Comparative efficacy and harms of duloxetine, milnacipran, and pregabalin in fibromyalgia syndrome.
Topics: Analgesics; Cyclopropanes; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Milnacipran; Pregabalin; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2010 |
Mixed incontinence: current evidence and future perspectives.
Topics: Adrenergic Uptake Inhibitors; Benzhydryl Compounds; Clinical Trials as Topic; Cresols; Duloxetine Hydrochloride; Estrogens; Female; Humans; Muscarinic Antagonists; Phenylpropanolamine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Tolterodine Tartrate; Treatment Outcome; Urinary Incontinence; Urinary Incontinence, Stress; Urinary Incontinence, Urge | 2010 |
Safety and tolerability of duloxetine in the acute management of diabetic peripheral neuropathic pain: analysis of pooled data from three placebo-controlled clinical trials.
Topics: Adrenergic Uptake Inhibitors; Chronic Disease; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neuralgia; Polypharmacy; Randomized Controlled Trials as Topic; Thiophenes | 2010 |
Comparative pain and mood effects in patients with comorbid fibromyalgia and major depressive disorder: secondary analyses of four pooled randomized controlled trials of duloxetine.
Topics: Adult; Affect; Antidepressive Agents; Comorbidity; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Pain; Pain Measurement; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Severity of Illness Index; Thiophenes | 2011 |
Effect of duloxetine in patients with fibromyalgia: tiredness subgroups.
Topics: Duloxetine Hydrochloride; Fatigue; Fibromyalgia; Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Recovery of Function; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2010 |
Treating diabetic peripheral neuropathic pain.
Topics: Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Complementary Therapies; Diabetic Neuropathies; Drug Interactions; Drug Therapy, Combination; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Humans; Pain; Pain Measurement; Pregabalin; Recovery of Function; Thiophenes | 2010 |
Pharmacological and clinical profile of newer antidepressants: implications for the treatment of elderly patients.
Topics: Aged; Antidepressive Agents; Citalopram; Clinical Trials as Topic; Cyclohexanols; Depressive Disorder, Major; Desvenlafaxine Succinate; Drug Interactions; Duloxetine Hydrochloride; Humans; Thiophenes | 2010 |
The treatment of stress incontinence in men: part 2 of a series of articles on incontinence.
Topics: Adrenergic Uptake Inhibitors; Behavior Therapy; Duloxetine Hydrochloride; Electric Stimulation Therapy; Humans; Male; Prostatectomy; Thiophenes; Urinary Incontinence, Stress; Urologic Surgical Procedures, Male | 2010 |
Urinary incontinence in the elderly: part 3 of a series of articles on incontinence.
Topics: Age Factors; Aged; Aged, 80 and over; Cholinergic Antagonists; Combined Modality Therapy; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk Factors; Thiophenes; Urinary Bladder, Overactive; Urinary Incontinence; Urinary Incontinence, Stress; Urinary Incontinence, Urge | 2010 |
Duloxetine for the treatment of fibromyalgia.
Topics: Clinical Trials as Topic; Duloxetine Hydrochloride; Fibromyalgia; Humans; Pain; Pain Measurement; Thiophenes | 2010 |
A systematic review of duloxetine and venlafaxine in major depression, including unpublished data.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cyclohexanols; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Resistance; Duloxetine Hydrochloride; Humans; Pharmacological Phenomena; Randomized Controlled Trials as Topic; Remission Induction; Therapeutic Equivalency; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2011 |
Duloxetine treatment and glycemic controls in patients with diagnoses other than diabetic peripheral neuropathic pain: a meta-analysis.
Topics: Antidepressive Agents; Anxiety Disorders; Blood Glucose; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Glycemic Index; Humans; Hyperglycemia; Male; Middle Aged; Mood Disorders; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2010 |
Efficacy and safety of duloxetine in fibromyalgia.
Topics: Antidepressive Agents; Clinical Trials as Topic; Duloxetine Hydrochloride; Fibromyalgia; Humans; Thiophenes | 2010 |
Treatment of neuropathic pain.
Topics: Antidepressive Agents, Tricyclic; Duloxetine Hydrochloride; Humans; Neuralgia; Peripheral Nervous System Diseases; Thiophenes | 2010 |
Novel antidepressants and panic disorder: evidence beyond current guidelines.
Topics: Antidepressive Agents; Clinical Trials as Topic; Cyclopropanes; Duloxetine Hydrochloride; Humans; Mianserin; Milnacipran; Mirtazapine; Morpholines; Panic Disorder; Practice Guidelines as Topic; Reboxetine; Thiophenes | 2011 |
Comparative efficacy and acceptability of amitriptyline, duloxetine and milnacipran in fibromyalgia syndrome: a systematic review with meta-analysis.
Topics: Amitriptyline; Antidepressive Agents; Cyclopropanes; Duloxetine Hydrochloride; Fibromyalgia; Humans; Milnacipran; Thiophenes; Treatment Outcome | 2011 |
Pregabalin, the lidocaine plaster and duloxetine in patients with refractory neuropathic pain: a systematic review.
Topics: Analgesics; Anesthetics, Local; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Humans; Lidocaine; Neuralgia; Pregabalin; Thiophenes; Treatment Outcome | 2010 |
Urinary incontinence in 2010: the evolution of SUI management.
Topics: Animals; Disease Management; Duloxetine Hydrochloride; Female; Humans; Male; Prostatectomy; Sex Factors; Thiophenes; Urinary Incontinence, Stress | 2011 |
Weight change with long-term duloxetine use in chronic painful conditions: an analysis of 16 clinical studies.
Topics: Aged; Analgesics; Arthralgia; Chronic Disease; Controlled Clinical Trials as Topic; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Knee Joint; Low Back Pain; Male; Middle Aged; Osteoarthritis, Knee; Pain; Thiophenes; Weight Gain; Weight Loss | 2011 |
Duloxetine: clinical pharmacokinetics and drug interactions.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Animals; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pharmacogenetics; Risk Assessment; Risk Factors; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2011 |
Cost-effectiveness analysis of a new 8% capsaicin patch compared to existing therapies for postherpetic neuralgia.
Topics: Administration, Topical; Amines; Anesthetics, Local; Antidepressive Agents, Tricyclic; Capsaicin; Clinical Trials as Topic; Costs and Cost Analysis; Cyclohexanecarboxylic Acids; Dopamine Uptake Inhibitors; Duloxetine Hydrochloride; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Male; Markov Chains; Neuralgia, Postherpetic; Pregabalin; Quality of Life; Sensory System Agents; Thiophenes; Transdermal Patch | 2011 |
Adverse reactions to duloxetine in depression.
Topics: Animals; Antidepressive Agents; Depression; Duloxetine Hydrochloride; Humans; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2011 |
Urinary incontinence: pharmacotherapy options.
Topics: Adrenergic Uptake Inhibitors; Animals; Drug Approval; Duloxetine Hydrochloride; Humans; Muscarinic Antagonists; Quality of Life; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress; Urinary Incontinence, Urge | 2011 |
Pharmacotherapy of fibromyalgia.
Topics: Analgesics; Animals; Antidepressive Agents; Clinical Trials as Topic; Cyclopropanes; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Milnacipran; Pregabalin; Thiophenes | 2011 |
Neoteric pharmacotherapeutic targets in fibromyalgia.
Topics: Animals; Cyclopropanes; Drug Approval; Drug Delivery Systems; Drug Design; Duloxetine Hydrochloride; Female; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Milnacipran; Pregabalin; Thiophenes; United States; United States Food and Drug Administration | 2011 |
Duloxetine in the treatment of depression: an overview.
Topics: Animals; Antidepressive Agents; Depression; Duloxetine Hydrochloride; Humans; Psychotherapy; Thiophenes | 2011 |
Case scenario: opioid association with serotonin syndrome: implications to the practitioners.
Topics: Analgesics, Opioid; Antidepressive Agents, Tricyclic; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhibitors; Depressive Disorder; Desipramine; Drug Interactions; Duloxetine Hydrochloride; Fentanyl; Humans; Male; Methadone; Middle Aged; Oxycodone; Polypharmacy; Pyrazoles; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Sulfonamides; Thiophenes; Transdermal Patch | 2011 |
Fibromyalgia and sleep.
Topics: Analgesics; Central Nervous System Sensitization; Chronic Pain; Cyclopropanes; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Milnacipran; Physical Therapy Modalities; Polysomnography; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sleep; Sleep Wake Disorders; Syndrome; Thiophenes | 2011 |
Pharmacotherapy of fibromyalgia.
Topics: Analgesics; Chronic Pain; Clinical Trials as Topic; Cognition Disorders; Cyclopropanes; Duloxetine Hydrochloride; Fatigue; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Milnacipran; Mood Disorders; Pain Management; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sleep Wake Disorders; Syndrome; Thiophenes; Treatment Outcome | 2011 |
Clinically relevant outcomes based on analysis of pooled data from 2 trials of duloxetine in patients with knee osteoarthritis.
Topics: Adrenergic Uptake Inhibitors; Aged; Chronic Pain; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2012 |
Second-generation antidepressants for seasonal affective disorder.
Topics: Adult; Antidepressive Agents, Second-Generation; Citalopram; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Morpholines; Phototherapy; Randomized Controlled Trials as Topic; Reboxetine; Seasonal Affective Disorder; Thiophenes | 2011 |
Predictors of remission with placebo using an integrated study database from patients with major depressive disorder.
Topics: Adult; Age of Onset; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Models, Theoretical; Placebo Effect; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Regression Analysis; Remission Induction; ROC Curve; Thiophenes; Treatment Outcome | 2012 |
A systematic review of duloxetine for osteoarthritic pain: what is the number needed to treat, number needed to harm, and likelihood to be helped or harmed?
Topics: Chronic Pain; Duloxetine Hydrochloride; Humans; Musculoskeletal Pain; Osteoarthritis; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2012 |
Preclinical discovery of duloxetine for the treatment of depression.
Topics: Animals; Antidepressive Agents; Depressive Disorder, Major; Drug Evaluation, Preclinical; Duloxetine Hydrochloride; Humans; Thiophenes | 2012 |
Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Adult; Affect; Autonomic Agents; Body Temperature Regulation; Carbazoles; Carvedilol; Clonidine; Cross-Over Studies; Dopamine Uptake Inhibitors; Doxazosin; Duloxetine Hydrochloride; Female; Hemodynamics; Humans; Light; Male; Miosis; Morpholines; Mydriasis; Mydriatics; N-Methyl-3,4-methylenedioxyamphetamine; Propanolamines; Randomized Controlled Trials as Topic; Reaction Time; Reboxetine; Recovery of Function; Reflex, Pupillary; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Young Adult | 2012 |
A review of duloxetine 60 mg once-daily dosing for the management of diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain due to chronic osteoarthritis pain and low back pain.
Topics: Analgesics; Chronic Pain; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Low Back Pain; Musculoskeletal Pain; Osteoarthritis; Thiophenes | 2013 |
[Drug therapy of fibromyalgia syndrome. Systematic review, meta-analysis and guideline].
Topics: Amitriptyline; Analgesics; Analgesics, Opioid; Antidepressive Agents; Anxiety Disorders; Combined Modality Therapy; Comorbidity; Cooperative Behavior; Depressive Disorder, Major; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Germany; Humans; Interdisciplinary Communication; Off-Label Use; Patient Care Team; Pregabalin; Somatoform Disorders; Thiophenes | 2012 |
Evaluation of the effect of duloxetine treatment on functioning as measured by the Sheehan disability scale: pooled analysis of data from six randomized, double-blind, placebo-controlled clinical studies.
Topics: Adult; Aged; Depressive Disorder, Major; Disability Evaluation; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Severity of Illness Index; Statistics as Topic; Thiophenes; Treatment Outcome | 2012 |
Duloxetine versus other anti-depressive agents for depression.
Topics: Antidepressive Agents; Citalopram; Cyclohexanols; Depression; Desvenlafaxine Succinate; Dibenzothiazepines; Duloxetine Hydrochloride; Fluoxetine; Humans; Paroxetine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Thiophenes; Venlafaxine Hydrochloride | 2012 |
Safety and tolerability of duloxetine in elderly patients with major depressive disorder: a pooled analysis of two placebo-controlled studies.
Topics: Adrenergic Uptake Inhibitors; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Least-Squares Analysis; Male; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome | 2013 |
Duloxetine: a review of its use in the management of major depressive disorder in older adults.
Topics: Aged; Animals; Depressive Disorder, Major; Drug Dosage Calculations; Duloxetine Hydrochloride; Humans; Thiophenes | 2013 |
Cost-effectiveness of duloxetine in chronic low back pain: a Quebec societal perspective.
Topics: Age Factors; Aged; Amitriptyline; Analgesics; Cardiovascular Diseases; Celecoxib; Chronic Disease; Clinical Trials as Topic; Cost-Benefit Analysis; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Humans; Hydromorphone; Low Back Pain; Markov Chains; Middle Aged; Models, Economic; Naproxen; Ontario; Osteoarthritis; Outcome Assessment, Health Care; Oxycodone; Pregabalin; Pyrazoles; Quality-Adjusted Life Years; Quebec; Sulfonamides; Thiophenes | 2013 |
Clinical inquiry: what medications are best for diabetic neuropathic pain?
Topics: Amines; Analgesics; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Practice Guidelines as Topic; Thiophenes | 2012 |
The treatment of iatrogenic male incontinence: latest results and future perspectives.
Topics: Antidepressive Agents; Behavior Therapy; Biofeedback, Psychology; Duloxetine Hydrochloride; Electric Stimulation Therapy; Equipment Design; Exercise Therapy; Humans; Iatrogenic Disease; Male; Muscle Contraction; Off-Label Use; Pelvic Floor; Prostatectomy; Stem Cells; Suburethral Slings; Thiophenes; Urinary Incontinence, Stress; Urinary Sphincter, Artificial | 2013 |
New treatments for osteoarthritis.
Topics: Biological Products; Duloxetine Hydrochloride; Humans; Injections, Intra-Articular; Mesenchymal Stem Cell Transplantation; Osteoarthritis, Knee; Platelet-Rich Plasma; Thiophenes; Tumor Necrosis Factor-alpha | 2013 |
Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia syndrome.
Topics: Adrenergic Uptake Inhibitors; Adult; Cyclopropanes; Duloxetine Hydrochloride; Fibromyalgia; Humans; Milnacipran; Norepinephrine; Quality of Life; Selective Serotonin Reuptake Inhibitors; Syndrome; Thiophenes | 2013 |
Clinical Reasoning: a 57-year-old man with jaw spasms.
Topics: Adrenergic Uptake Inhibitors; Amines; Anticonvulsants; Brain Neoplasms; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Facial Muscles; Gabapentin; gamma-Aminobutyric Acid; Hemangioma; Humans; Jaw; Male; Middle Aged; Spasm; Thiophenes | 2013 |
The role of duloxetine in stress urinary incontinence: a systematic review and meta-analysis.
Topics: Duloxetine Hydrochloride; Female; Humans; Quality of Life; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress; Urination | 2013 |
Treatment of painful peripheral neuropathy.
Topics: Analgesics; Antidepressive Agents; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain Management; Pregabalin; Randomized Controlled Trials as Topic; Thiophenes | 2013 |
Treatment response for acute depression is not associated with number of previous episodes: lack of evidence for a clinical staging model for major depressive disorder.
Topics: Acute Disease; Adult; Antidepressive Agents; Citalopram; Cyclohexanols; Depression; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Paroxetine; Recurrence; Thiophenes; Time Factors; Treatment Outcome; Venlafaxine Hydrochloride | 2013 |
Efficacy of duloxetine versus alternative oral therapies: an indirect comparison of randomised clinical trials in chronic low back pain.
Topics: Administration, Oral; Analgesics; Chronic Pain; Duloxetine Hydrochloride; Humans; Low Back Pain; Randomized Controlled Trials as Topic; Thiophenes | 2013 |
Mechanisms and management of diabetic painful distal symmetrical polyneuropathy.
Topics: Diabetic Neuropathies; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Humans; Pain; Peripheral Nervous System Diseases; Pregabalin; Thiophenes | 2013 |
Transient receptor potential ion channels: powerful regulators of cell function.
Topics: Analgesics; Anti-Inflammatory Agents; Biomarkers; Calcium Channels; Capsaicin; Chronic Pain; Duloxetine Hydrochloride; Humans; Inflammation; Macrophages; Melanoma; Monocytes; Nerve Tissue Proteins; Pain, Postoperative; Respiratory Tract Diseases; Surgical Wound Infection; Thiophenes; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels | 2014 |
Use of serotonin norepinephrine reuptake inhibitors in the treatment of attention-deficit hyperactivity disorder in pediatrics.
Topics: Adrenergic Uptake Inhibitors; Attention Deficit Disorder with Hyperactivity; Cyclohexanols; Duloxetine Hydrochloride; Humans; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Venlafaxine Hydrochloride | 2014 |
Treatment of hidradenitis supprurativa associated pain with nonsteroidal anti-inflammatory drugs, acetaminophen, celecoxib, gabapentin, pegabalin, duloxetine, and venlafaxine.
Topics: Acetaminophen; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclohexanecarboxylic Acids; Cyclohexanols; Drug Therapy, Combination; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hidradenitis Suppurativa; Humans; Pain; Pain Management; Pregabalin; Pyrazoles; Selective Serotonin Reuptake Inhibitors; Sulfonamides; Thiophenes; Venlafaxine Hydrochloride | 2013 |
Duloxetine for treating painful neuropathy, chronic pain or fibromyalgia.
Topics: Adult; Analgesics; Chronic Pain; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Neuralgia; Randomized Controlled Trials as Topic; Thiophenes | 2014 |
Bad medicine: the rise of duloxetine.
Topics: Biomedical Research; Drug Industry; Drug Prescriptions; Duloxetine Hydrochloride; Humans; Prescription Drugs; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2014 |
Antidepressants in the treatment for chronic low back pain: questioning the validity of meta-analyses.
Topics: Analgesics; Antidepressive Agents; Duloxetine Hydrochloride; Humans; Low Back Pain; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Review Literature as Topic; Thiophenes | 2014 |
Depression symptom clusters and their predictive value for treatment outcomes: results from an individual patient data meta-analysis of duloxetine trials.
Topics: Clinical Trials as Topic; Cluster Analysis; Databases, Factual; Depression; Duloxetine Hydrochloride; Female; Humans; Male; Predictive Value of Tests; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2014 |
Serotonin-norepinephrine reuptake inhibitors for the management of chemotherapy-induced peripheral neuropathy.
Topics: Antineoplastic Agents; Cyclohexanols; Cyclopropanes; Desvenlafaxine Succinate; Duloxetine Hydrochloride; Humans; Milnacipran; Neurotransmitter Uptake Inhibitors; Norepinephrine; Organoplatinum Compounds; Oxaliplatin; Peripheral Nervous System Diseases; Serotonin; Thiophenes; Venlafaxine Hydrochloride | 2014 |
The efficacy of duloxetine, non-steroidal anti-inflammatory drugs, and opioids in osteoarthritis: a systematic literature review and meta-analysis.
Topics: Acetaminophen; Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Bayes Theorem; Drug Evaluation; Duloxetine Hydrochloride; Etoricoxib; Humans; Narcotics; Osteoarthritis; Pain Measurement; Pyridines; Sulfones; Thiophenes; Treatment Outcome | 2014 |
Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline.
Topics: Adult; Amines; Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Antineoplastic Agents; Baclofen; Comorbidity; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Duloxetine Hydrochloride; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Gels; Humans; Incidence; Ketamine; Neoplasms; Neuralgia; Peripheral Nervous System Diseases; Quality of Life; Randomized Controlled Trials as Topic; Severity of Illness Index; Survivors; Thiophenes; Treatment Outcome; United States | 2014 |
Painful diabetic neuropathy.
Topics: Amines; Analgesics; Analgesics, Opioid; Biopsy; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypoglycemic Agents; Pregabalin; Sensory Thresholds; Skin; Thiophenes; Touch Perception | 2014 |
Benefits and harms in clinical trials of duloxetine for treatment of major depressive disorder: comparison of clinical study reports, trial registries, and publications.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Clinical Protocols; Clinical Trials as Topic; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Registries; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2014 |
Bioactivation potential of thiophene-containing drugs.
Topics: Antidepressive Agents; Cytochrome P-450 Enzyme System; Depression; Duloxetine Hydrochloride; Hepatitis; Humans; Platelet Aggregation Inhibitors; Thiophenes; Ticrynafen | 2014 |
Application of the Gradient Boosted method in randomised clinical trials: Participant variables that contribute to depression treatment efficacy of duloxetine, SSRIs or placebo.
Topics: Adult; Aged; Depression; Depressive Disorder; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Regression Analysis; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2014 |
[If the general practitioner has to decide: what is the evidence for the selection of antidepressants?].
Topics: Acetamides; Antidepressive Agents; Citalopram; Cyclohexanols; Depressive Disorder; Duloxetine Hydrochloride; Evidence-Based Medicine; General Practice; Germany; Guideline Adherence; Humans; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2014 |
Drugs for osteoarthritis.
Topics: Acetaminophen; Adrenal Cortex Hormones; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Capsaicin; Chondroitin; Dietary Supplements; Duloxetine Hydrochloride; Glucosamine; Humans; Hyaluronic Acid; Injections, Intra-Articular; Osteoarthritis; Thiophenes; Tramadol | 2014 |
Relative efficacy and tolerability of vortioxetine versus selected antidepressants by indirect comparisons of similar clinical studies.
Topics: Acetamides; Adult; Aged; Antidepressive Agents; Benzofurans; Citalopram; Cyclohexanols; Depressive Disorder, Major; Desvenlafaxine Succinate; Duloxetine Hydrochloride; Female; Humans; Hypnotics and Sedatives; Indoles; Male; Middle Aged; Piperazines; Selective Serotonin Reuptake Inhibitors; Sertraline; Sulfides; Thiophenes; Venlafaxine Hydrochloride; Vilazodone Hydrochloride; Vortioxetine | 2014 |
Current use of drugs affecting the central nervous system for chemotherapy-induced peripheral neuropathy in cancer patients: a systematic review.
Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents; Antineoplastic Agents; Boronic Acids; Bortezomib; Carbamazepine; Central Nervous System; Cyclohexanols; Duloxetine Hydrochloride; Epothilones; Humans; Neoplasms; Neuralgia; Oxcarbazepine; Peripheral Nervous System Diseases; Pyrazines; Taxoids; Thalidomide; Thiophenes; Venlafaxine Hydrochloride; Vinca Alkaloids | 2015 |
[Chemotherapy-induced neuropathy].
Topics: Analgesics; Antineoplastic Agents; Duloxetine Hydrochloride; Evidence-Based Medicine; Humans; Peripheral Nervous System Diseases; Thiophenes; Treatment Outcome | 2015 |
Chemotherapy-induced peripheral neuropathy in patients treated with taxanes and platinum derivatives.
Topics: Antidepressive Agents; Antineoplastic Agents; Duloxetine Hydrochloride; Humans; Organoplatinum Compounds; Oxaliplatin; Peripheral Nervous System Diseases; Platinum Compounds; Quality of Life; Risk Factors; Taxoids; Thiophenes | 2015 |
Nocebo effects in the treatment of major depression: results from an individual study participant-level meta-analysis of the placebo arm of duloxetine clinical trials.
Topics: Antidepressive Agents; Controlled Clinical Trials as Topic; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Nocebo Effect; Thiophenes; Treatment Outcome | 2015 |
[DRUG THERAPY OF NEUROPATHIC PAIN BASED ON THE LATEST RECOMMENDATIONS].
Topics: Amines; Amitriptyline; Analgesics, Non-Narcotic; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Practice Guidelines as Topic; Pregabalin; Thiophenes | 2015 |
Current Status of Pain Management in Parkinson's Disease.
Topics: Acetylcholine Release Inhibitors; Alanine; Analgesics; Antiparkinson Agents; Apomorphine; Benzylamines; Botulinum Toxins, Type A; Deep Brain Stimulation; Dopamine Agonists; Drug Combinations; Duloxetine Hydrochloride; Humans; Levodopa; Naloxone; Oxycodone; Pain; Pain Management; Pain Measurement; Pain Threshold; Parkinson Disease; Tetrahydronaphthalenes; Thiophenes | 2020 |
Second-generation antidepressants for treatment of seasonal affective disorder.
Topics: Adult; Antidepressive Agents, Second-Generation; Bias; Citalopram; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Morpholines; Observational Studies as Topic; Phototherapy; Placebos; Quality of Life; Randomized Controlled Trials as Topic; Reboxetine; Seasonal Affective Disorder; Thiophenes; Treatment Outcome | 2021 |
Duloxetine for fibromyalgia syndrome: a systematic review and meta-analysis.
Topics: Adult; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Pain; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2023 |
259 trial(s) available for duloxetine hydrochloride and thiophenes
| Article | Year |
|---|---|
An open-label study of duloxetine hydrochloride, a mixed serotonin and noradrenaline reuptake inhibitor, in patients with DSM-III-R major depressive disorder. Lilly Duloxetine Depression Study Group.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; Depressive Disorder; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Thiophenes | 1997 |
Pharmacokinetics and safety of duloxetine, a dual-serotonin and norepinephrine reuptake inhibitor.
Topics: Adrenergic Uptake Inhibitors; Adult; Blood Pressure; Duloxetine Hydrochloride; Heart Rate; Humans; Male; Middle Aged; Models, Biological; Selective Serotonin Reuptake Inhibitors; Single-Blind Method; Thiophenes | 2000 |
Assessment of the serotonin and norepinephrine reuptake blocking properties of duloxetine in healthy subjects.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Blood Pressure; Brain; Brain Chemistry; Clomipramine; Depression; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Male; Norepinephrine; Reference Values; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Tyramine | 2001 |
Duloxetine in the treatment of major depressive disorder: a double-blind clinical trial.
Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Blood Pressure; Body Weight; Depressive Disorder, Major; Dopamine Uptake Inhibitors; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2002 |
Duloxetine, 60 mg once daily, for major depressive disorder: a randomized double-blind placebo-controlled trial.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Pain Measurement; Placebos; Psychiatric Status Rating Scales; Somatoform Disorders; Thiophenes; Treatment Outcome | 2002 |
Duloxetine versus placebo in the treatment of stress urinary incontinence.
Topics: Analysis of Variance; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Nausea; Neurotransmitter Uptake Inhibitors; Quality of Life; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2002 |
Duloxetine increases serotonin and norepinephrine availability in healthy subjects: a double-blind, controlled study.
Topics: Adult; Antidepressive Agents; Blood Pressure; Cross-Over Studies; Desipramine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Heart Rate; Humans; Male; Mandelic Acids; Methoxyhydroxyphenylglycol; Norepinephrine; Normetanephrine; Serotonin; Sympathomimetics; Thiophenes; Time Factors; Tyramine | 2003 |
Mixed urinary incontinence symptoms: urodynamic findings, incontinence severity, and treatment response.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Middle Aged; Probability; Quality of Life; Reference Values; Severity of Illness Index; Thiophenes; Treatment Outcome; Urinary Incontinence; Urinary Incontinence, Stress; Urodynamics | 2003 |
Validation of two global impression questionnaires for incontinence.
Topics: Body Mass Index; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Patient Satisfaction; Placebos; Quality of Life; Severity of Illness Index; Surveys and Questionnaires; Thiophenes; United States; Urinary Incontinence, Stress | 2003 |
Duloxetine in treatment of anxiety symptoms associated with depression.
Topics: Adult; Antidepressive Agents; Anxiety; Depression; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Severity of Illness Index; Surveys and Questionnaires; Thiophenes | 2003 |
Duloxetine versus placebo for the treatment of North American women with stress urinary incontinence.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Middle Aged; North America; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2003 |
Duloxetine in the long-term treatment of major depressive disorder.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Antidepressive Agents; Chronic Disease; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Long-Term Care; Male; Middle Aged; Personality Inventory; Thiophenes; Treatment Outcome | 2003 |
Effect of age on the pharmacokinetics of duloxetine in women.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Aging; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence | 2004 |
Duloxetine vs placebo in the treatment of stress urinary incontinence: a four-continent randomized clinical trial.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Patient Compliance; Quality of Life; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2004 |
Duloxetine versus placebo in the treatment of European and Canadian women with stress urinary incontinence.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Double-Blind Method; Duloxetine Hydrochloride; Female; Heart Rate; Humans; Middle Aged; Quality of Life; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2004 |
Effect of duloxetine on tolterodine pharmacokinetics in healthy volunteers.
Topics: Adrenergic Uptake Inhibitors; Adult; Area Under Curve; Benzhydryl Compounds; Cresols; Cross-Over Studies; Double-Blind Method; Drug Combinations; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Muscarinic Antagonists; Phenylpropanolamine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Tolterodine Tartrate | 2004 |
The effect of duloxetine on painful physical symptoms in depressed patients: do improvements in these symptoms result in higher remission rates?
Topics: Adult; Antidepressive Agents; Comorbidity; Depressive Disorder; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Multicenter Studies as Topic; Pain; Pain Measurement; Placebos; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Severity of Illness Index; Thiophenes; Treatment Outcome | 2004 |
Validation of a clinical algorithm to diagnose stress urinary incontinence for large studies.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Predictive Value of Tests; Randomized Controlled Trials as Topic; Reproducibility of Results; Thiophenes; Urinary Incontinence, Stress | 2004 |
Clinical assessment of norepinephrine transporter blockade through biochemical and pharmacological profiles.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Heart Rate; Humans; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Posture; Radioligand Assay; Sensitivity and Specificity; Symporters; Systole; Thiophenes; Tyramine | 2004 |
Duloxetine in the treatment of depression: a double-blind placebo-controlled comparison with paroxetine.
Topics: Adult; Analysis of Variance; Confidence Intervals; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Logistic Models; Male; Middle Aged; Paroxetine; Sleep Initiation and Maintenance Disorders; Thiophenes | 2004 |
Comparative effects of duloxetine and desipramine on sleep EEG in healthy subjects.
Topics: Adolescent; Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cross-Over Studies; Desipramine; Double-Blind Method; Duloxetine Hydrochloride; Electroencephalography; Female; Humans; Male; Norepinephrine; Polysomnography; Serotonin; Sleep; Sleep Stages; Surveys and Questionnaires; Thiophenes | 2005 |
The effect of previous treatment experience and incontinence severity on the placebo response of stress urinary incontinence.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Aged, 80 and over; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Muscle Contraction; Pelvic Floor; Placebo Effect; Randomized Controlled Trials as Topic; Retreatment; Thiophenes; Urinary Incontinence, Stress | 2004 |
Pharmacological treatment of women awaiting surgery for stress urinary incontinence.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Urinary Incontinence, Stress | 2004 |
A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder.
Topics: Comorbidity; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Neurotransmitter Uptake Inhibitors; Sex Factors; Thiophenes; Treatment Outcome | 2004 |
Duloxetine 60 mg once-daily in the treatment of painful physical symptoms in patients with major depressive disorder.
Topics: Administration, Oral; Adult; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Placebos; Severity of Illness Index; Thiophenes; Treatment Outcome | 2005 |
Incidence and duration of antidepressant-induced nausea: duloxetine compared with paroxetine and fluoxetine.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antidepressive Agents; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Europe; Female; Fluoxetine; Humans; Male; Middle Aged; Nausea; Paroxetine; Prevalence; Severity of Illness Index; Sex Factors; Thiophenes; Time Factors; United States | 2004 |
Duloxetine in the acute and long-term treatment of major depressive disorder: a placebo- and paroxetine-controlled trial.
Topics: Adult; Antidepressive Agents, Second-Generation; Body Weight; Cardiovascular Diseases; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Electrocardiography; Female; Hemodynamics; Humans; Longitudinal Studies; Male; Middle Aged; Paroxetine; Psychiatric Status Rating Scales; Sexual Dysfunction, Physiological; Thiophenes | 2004 |
Onset of action for duloxetine 60 mg once daily: double-blind, placebo-controlled studies.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Placebos; Severity of Illness Index; Thiophenes; Time Factors; Treatment Outcome | 2005 |
Duloxetine pharmacokinetics in cirrhotics compared with healthy subjects.
Topics: Administration, Oral; Adult; Area Under Curve; Duloxetine Hydrochloride; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2005 |
A randomized controlled trial of duloxetine alone, pelvic floor muscle training alone, combined treatment and no active treatment in women with stress urinary incontinence.
Topics: Adult; Aged; Combined Modality Therapy; Double-Blind Method; Duloxetine Hydrochloride; Exercise Therapy; Female; Humans; Middle Aged; Pelvic Floor; Thiophenes; Urinary Incontinence, Stress | 2005 |
Duloxetine vs. placebo in patients with painful diabetic neuropathy.
Topics: Aged; Demography; Depression; Diabetic Neuropathies; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain Measurement; Personality Inventory; Placebos; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2005 |
Sexual functioning assessed in 4 double-blind placebo- and paroxetine-controlled trials of duloxetine for major depressive disorder.
Topics: Adult; Antidepressive Agents; Comorbidity; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Incidence; Male; Middle Aged; Paroxetine; Placebos; Selective Serotonin Reuptake Inhibitors; Sexual Behavior; Sexual Dysfunctions, Psychological; Thiophenes; Treatment Outcome | 2005 |
Duloxetine for the treatment of stress urinary incontinence in women: an integrated analysis of safety.
Topics: Adult; Aged; Aged, 80 and over; Constipation; Diarrhea; Disorders of Excessive Somnolence; Dizziness; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Duloxetine Hydrochloride; Fatigue; Female; Headache; Humans; Liver; Middle Aged; Nausea; Sleep Initiation and Maintenance Disorders; Thiophenes; Urinary Incontinence, Stress; Xerostomia | 2006 |
A randomized, double-blind, placebo-controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Antidepressive Agents; Comorbidity; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Middle Aged; Pain Measurement; Placebo Effect; Quality of Life; Thiophenes; Treatment Outcome; United States; Women's Health | 2005 |
Duloxetine versus routine care in the long-term management of diabetic peripheral neuropathic pain.
Topics: Amines; Amitriptyline; Analysis of Variance; Cyclohexanecarboxylic Acids; Cyclohexanols; Diabetic Neuropathies; Double-Blind Method; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2006 |
A dose-finding study of duloxetine based on serotonin transporter occupancy.
Topics: Adult; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Magnetic Resonance Imaging; Male; Positron-Emission Tomography; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Thiophenes | 2006 |
Duloxetine in the prevention of relapse of major depressive disorder: double-blind placebo-controlled study.
Topics: Adult; Analysis of Variance; Depressive Disorder; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2006 |
Management of depression relapse: re-initiation of duloxetine treatment or dose increase.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Long-Term Care; Male; Middle Aged; Recurrence; Thiophenes; Treatment Outcome | 2006 |
Duloxetine in the treatment of major depressive disorder: a placebo- and paroxetine-controlled trial.
Topics: Adult; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Mass Screening; Middle Aged; Paroxetine; Placebo Effect; Prevalence; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2006 |
Duloxetine 60 mg once daily in the treatment of milder major depressive disorder.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Thiophenes; Treatment Outcome | 2006 |
Minimal clinically important differences in Incontinence Quality-of-Life scores in stress urinary incontinence.
Topics: Duloxetine Hydrochloride; Female; Humans; Middle Aged; Quality of Life; Surveys and Questionnaires; Thiophenes; Urinary Incontinence, Stress | 2006 |
Economic evaluation of duloxetine for the treatment of women with stress urinary incontinence: a Markov model comparing pharmacotherapy with pelvic floor muscle training.
Topics: Adrenergic Uptake Inhibitors; Aged; Cost-Benefit Analysis; Double-Blind Method; Duloxetine Hydrochloride; Exercise Therapy; Female; Humans; Markov Chains; Middle Aged; Models, Statistical; Patient Dropouts; Pelvic Floor; Prospective Studies; Thiophenes; Treatment Outcome; Urinary Incontinence | 2006 |
Cost-effectiveness of duloxetine versus routine treatment for U.S. patients with diabetic peripheral neuropathic pain.
Topics: Adrenergic Uptake Inhibitors; Aged; Amines; Amitriptyline; Analgesia; Analgesics; Brain; Cohort Studies; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Cyclohexanols; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Norepinephrine; Pain Measurement; Pain Threshold; Placebo Effect; Serotonin; Thiophenes; Treatment Outcome; United States; Venlafaxine Hydrochloride | 2006 |
Duloxetine for the treatment of major depressive disorder: safety and tolerability associated with dose escalation.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Duloxetine Hydrochloride; Female; Humans; Long-Term Care; Male; Middle Aged; Personality Inventory; Thiophenes; Treatment Outcome | 2007 |
Treatment benefits of duloxetine in major depressive disorder as assessed by number needed to treat.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Paroxetine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2006 |
Duloxetine in the treatment of major depressive disorder: an assessment of the relationship between outcomes and episode characteristics.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Thiophenes; Treatment Outcome | 2006 |
Pharmacologic treatment in postprostatectomy stress urinary incontinence.
Topics: Adrenergic Uptake Inhibitors; Aged; Analysis of Variance; Combined Modality Therapy; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Postoperative Complications; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Quality of Life; Statistics, Nonparametric; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2007 |
A randomized controlled trial of duloxetine in diabetic peripheral neuropathic pain.
Topics: Acetaminophen; Adrenergic Uptake Inhibitors; Aged; Analgesics, Non-Narcotic; Diabetic Neuropathies; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neuralgia; Norepinephrine; Pain; Palliative Care; Peripheral Nervous System Diseases; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Treatment Outcome | 2006 |
Duloxetine in the treatment of women with stress urinary incontinence: results from DESIRE (Duloxetine Efficacy and Safety for Incontinence in Racial and Ethnic populations).
Topics: Adult; Aged; Aged, 80 and over; Black or African American; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Hispanic or Latino; Humans; Middle Aged; Quality of Life; Self-Assessment; Severity of Illness Index; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress; White People | 2006 |
Effect of dose escalation on the tolerability and efficacy of duloxetine in the treatment of women with stress urinary incontinence.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Nausea; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2007 |
The dual serotonin and noradrenaline reuptake inhibitor duloxetine for the treatment of interstitial cystitis: results of an observational study.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Cystitis, Interstitial; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2007 |
Comparison of duloxetine, escitalopram, and sertraline effects on cytochrome P450 2D6 function in healthy volunteers.
Topics: Adult; Antidepressive Agents; Citalopram; Cytochrome P-450 CYP2D6; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Male; Metoprolol; Middle Aged; Reference Values; Sertraline; Single-Blind Method; Thiophenes | 2007 |
The efficacy of duloxetine in the treatment of premature ejaculation.
Topics: Adult; Duloxetine Hydrochloride; Ejaculation; Humans; Male; Selective Serotonin Reuptake Inhibitors; Sexual Dysfunction, Physiological; Thiophenes; Treatment Outcome | 2007 |
Duloxetine versus escitalopram and placebo in the treatment of patients with major depressive disorder: onset of antidepressant action, a non-inferiority study.
Topics: Adult; Antidepressive Agents; Arrhythmias, Cardiac; Citalopram; Depressive Disorder; Double-Blind Method; Duloxetine Hydrochloride; Erectile Dysfunction; Female; Gastrointestinal Diseases; Humans; Irritable Mood; Male; Middle Aged; Patient Dropouts; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Treatment Outcome; Xerostomia | 2007 |
Efficacy and safety of duloxetine in the treatment of generalized anxiety disorder: a flexible-dose, progressive-titration, placebo-controlled trial.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Anxiety Disorders; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Nausea; Placebos; Psychiatric Status Rating Scales; Severity of Illness Index; Sleep Wake Disorders; Thiophenes; Treatment Outcome | 2008 |
Impact of disease characteristics on the efficacy of duloxetine in diabetic peripheral neuropathic pain.
Topics: Adrenergic Uptake Inhibitors; Aged; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Humans; Least-Squares Analysis; Middle Aged; Neuritis; Pain Measurement; Placebos; Racial Groups; Safety; Thiophenes; Treatment Outcome | 2007 |
Duloxetine increases stage 3 sleep and suppresses rapid eye movement (REM) sleep in patients with major depression.
Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Electroencephalography; Female; Humans; Male; Middle Aged; Polysomnography; Prospective Studies; Psychiatric Status Rating Scales; Sleep Stages; Sleep, REM; Thiophenes | 2007 |
Duloxetine pharmacokinetics are similar in Japanese and Caucasian subjects.
Topics: Antidepressive Agents; Asian People; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Humans; Thiophenes; White People | 2007 |
QT effects of duloxetine at supratherapeutic doses: a placebo and positive controlled study.
Topics: Adolescent; Adult; Age Factors; Aged; Anti-Infective Agents; Antidepressive Agents; Aza Compounds; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Electrocardiography; Female; Fluoroquinolones; Guideline Adherence; Humans; Middle Aged; Moxifloxacin; Practice Guidelines as Topic; Quinolines; Thiophenes | 2007 |
Duloxetine as an SNRI treatment for generalized anxiety disorder: results from a placebo and active-controlled trial.
Topics: Adult; Anxiety Disorders; Cyclohexanols; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Personality Inventory; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2007 |
A randomized, double-blind comparison of duloxetine and venlafaxine in the treatment of patients with major depressive disorder.
Topics: Adolescent; Adult; Antidepressive Agents; Cyclohexanols; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Severity of Illness Index; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2008 |
Once-daily duloxetine 60 mg in the treatment of major depressive disorder: multicenter, double-blind, randomized, paroxetine-controlled, non-inferiority trial in China, Korea, Taiwan and Brazil.
Topics: Activities of Daily Living; Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Blood Pressure; Brazil; China; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Heart Rate; Humans; Korea; Male; Middle Aged; Pain; Pain Measurement; Paroxetine; Psychiatric Status Rating Scales; Taiwan; Thiophenes; Weight Gain | 2007 |
Duloxetine treatment for role functioning improvement in generalized anxiety disorder: three independent studies.
Topics: Adult; Anxiety Disorders; Disabled Persons; Double-Blind Method; Duloxetine Hydrochloride; Female; Health Status; Humans; Male; Quality of Life; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2007 |
Duloxetine treatment of dysthymia and double depression: an open-label trial.
Topics: Adult; Depressive Disorder, Major; Duloxetine Hydrochloride; Dysthymic Disorder; Female; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2007 |
Duloxetine compared with placebo for treating women with symptoms of overactive bladder.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Aged, 80 and over; Analysis of Variance; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Thiophenes; Treatment Outcome; Urinary Bladder, Overactive; Urinary Incontinence, Urge; Urodynamics | 2007 |
Efficacy of duloxetine on cognition, depression, and pain in elderly patients with major depressive disorder: an 8-week, double-blind, placebo-controlled trial.
Topics: Age Factors; Aged; Antidepressive Agents; Back Pain; Cognition Disorders; Comorbidity; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Geriatric Assessment; Humans; Male; Neuropsychological Tests; Pain; Pain Measurement; Placebos; Psychiatric Status Rating Scales; Secondary Prevention; Thiophenes; Treatment Outcome | 2007 |
Duloxetine versus escitalopram and placebo: an 8-month, double-blind trial in patients with major depressive disorder.
Topics: Adolescent; Adult; Aged; Algorithms; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Placebos; Remission Induction; Thiophenes; Treatment Outcome | 2007 |
A comparative study of the efficacy of acute and continuation treatment with escitalopram versus duloxetine in patients with major depressive disorder.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Citalopram; Depressive Disorder, Major; Double-Blind Method; Drug Tolerance; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes | 2007 |
Double-blind comparison of escitalopram and duloxetine in the acute treatment of major depressive disorder.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Thiophenes | 2007 |
The effects of supratherapeutic doses of duloxetine on blood pressure and pulse rate.
Topics: Adult; Aged; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Electrocardiography; Female; Heart Rate; Humans; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes; United States | 2007 |
Duloxetine compared with placebo for the treatment of women with mixed urinary incontinence.
Topics: Adult; Aged; Aged, 80 and over; Canada; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Neurotransmitter Uptake Inhibitors; Patient Satisfaction; Quality of Life; Severity of Illness Index; Surveys and Questionnaires; Thiophenes; Treatment Outcome; United Kingdom; United States; Urinary Incontinence, Stress; Urinary Incontinence, Urge; Urodynamics | 2008 |
Time to response for duloxetine 60 mg once daily versus placebo in elderly patients with major depressive disorder.
Topics: Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Thiophenes; Time Factors | 2008 |
The safety and tolerability of duloxetine in depressed elderly patients with and without medical comorbidity.
Topics: Aged; Aged, 80 and over; Antidepressive Agents; Arthritis; Cardiovascular Diseases; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Pain; Pain Measurement; Severity of Illness Index; Thiophenes; Treatment Outcome | 2007 |
Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine.
Topics: Adult; Anxiety; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Hot Flashes; Humans; Middle Aged; Pain; Postmenopause; Selective Serotonin Reuptake Inhibitors; Single-Blind Method; Sleep Wake Disorders; Thiophenes; Treatment Outcome | 2007 |
Long-term tolerability and effectiveness of duloxetine in the treatment of major depressive disorder.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Long-Term Care; Male; Middle Aged; Patient Dropouts; Personality Inventory; Psychometrics; Recurrence; Substance Withdrawal Syndrome; Thiophenes; Treatment Outcome | 2008 |
Changes in sexual functioning associated with duloxetine, escitalopram, and placebo in the treatment of patients with major depressive disorder.
Topics: Adult; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Sexual Behavior; Sexual Dysfunctions, Psychological; Surveys and Questionnaires; Thiophenes | 2007 |
Pharmacokinetics and tolerability of duloxetine following oral administration to healthy Chinese subjects.
Topics: Administration, Oral; Adult; Area Under Curve; China; Dizziness; Double-Blind Method; Duloxetine Hydrochloride; Female; Half-Life; Humans; Male; Metabolic Clearance Rate; Nausea; Selective Serotonin Reuptake Inhibitors; Sex Factors; Thiophenes; Vomiting | 2007 |
An open-label 52-week clinical extension comparing duloxetine with routine care in patients with diabetic peripheral neuropathic pain.
Topics: Acetaminophen; Amitriptyline; Analgesics; Carbamazepine; Diabetes Complications; Diabetic Neuropathies; Diclofenac; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Lipids; Male; Meloxicam; Middle Aged; Neuralgia; Pentoxifylline; Selective Serotonin Reuptake Inhibitors; Thiamine; Thiazines; Thiazoles; Thioctic Acid; Thiophenes; Time; Vitamin B 12 | 2007 |
Duloxetine in the treatment of major depressive disorder: an open-label study.
Topics: Chronic Disease; Depressive Disorder, Major; Disability Evaluation; Duloxetine Hydrochloride; Humans; Quality of Life; Remission Induction; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Sexual Dysfunction, Physiological; Surveys and Questionnaires; Thiophenes; Treatment Outcome | 2007 |
Efficacy of duloxetine as a migraine preventive medication: possible predictors of response in a retrospective chart review.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Electronics, Medical; Female; Humans; Male; Middle Aged; Migraine Disorders; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Time Factors | 2007 |
A randomized, controlled trial of duloxetine alone vs. duloxetine plus a telephone intervention in the treatment of depression.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Combined Modality Therapy; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Patient Compliance; Personality Inventory; Referral and Consultation; Telephone; Thiophenes; Treatment Outcome | 2008 |
Differential antidepressant symptom efficacy: placebo-controlled comparisons of duloxetine and SSRIs (fluoxetine, paroxetine, escitalopram).
Topics: Adult; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Paroxetine; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Treatment Outcome | 2007 |
Measurement of duloxetine in blood using high-performance liquid chromatography with spectrophotometric detection and column switching.
Topics: Chromatography, High Pressure Liquid; Drug Interactions; Drug Monitoring; Duloxetine Hydrochloride; Female; Humans; Male; Molecular Structure; Selective Serotonin Reuptake Inhibitors; Spectrophotometry; Thiophenes | 2007 |
Efficacy and safety of duloxetine 60 mg once daily in the treatment of pain in patients with major depressive disorder and at least moderate pain of unknown etiology: a randomized controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Pain Measurement; Severity of Illness Index; Thiophenes | 2007 |
A comparison of initial duloxetine dosing strategies in patients with major depressive disorder.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Food-Drug Interactions; Humans; Male; Middle Aged; Outpatients; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2007 |
Duloxetine for the management of diabetic peripheral neuropathic pain: evidence-based findings from post hoc analysis of three multicenter, randomized, double-blind, placebo-controlled, parallel-group studies.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neuralgia; Peripheral Nervous System Diseases; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2007 |
Pharmacokinetics of duloxetine in breast milk and plasma of healthy postpartum women.
Topics: Administration, Oral; Adult; Algorithms; Area Under Curve; Blood Pressure; Body Mass Index; Capsules; Chromatography, Liquid; Dizziness; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Fatigue; Female; Headache; Heart Rate; Humans; Lactation; Milk, Human; Nausea; Postpartum Period; Selective Serotonin Reuptake Inhibitors; Tandem Mass Spectrometry; Thiophenes | 2008 |
Safety and tolerability of duloxetine at 60 mg once daily in elderly patients with major depressive disorder.
Topics: Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Thiophenes | 2008 |
Duloxetine versus placebo for the treatment of women with stress predominant urinary incontinence in Taiwan: a double-blind, randomized, placebo-controlled trial.
Topics: Adult; Aged; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Selective Serotonin Reuptake Inhibitors; Taiwan; Thiophenes; Urinary Incontinence, Stress | 2008 |
Duloxetine 1 year on: the long-term outcome of a cohort of women prescribed duloxetine.
Topics: Duloxetine Hydrochloride; Female; Humans; Longitudinal Studies; Patient Dropouts; Selective Serotonin Reuptake Inhibitors; Suburethral Slings; Thiophenes; Urinary Incontinence, Stress | 2008 |
Rescue pharmacotherapy with duloxetine for selective serotonin reuptake inhibitor nonresponders in late-life depression: outcome and tolerability.
Topics: Age of Onset; Aged; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Duloxetine Hydrochloride; Female; Humans; Male; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Surveys and Questionnaires; Thiophenes; Treatment Outcome | 2008 |
In vitro and in vivo evaluations of cytochrome P450 1A2 interactions with duloxetine.
Topics: Administration, Oral; Adult; Area Under Curve; Biological Availability; Cross-Over Studies; Cytochrome P-450 CYP1A2; Drug Interactions; Duloxetine Hydrochloride; Female; Fluvoxamine; Humans; Infusions, Intravenous; Male; Microsomes, Liver; Middle Aged; Selective Serotonin Reuptake Inhibitors; Sex Factors; Smoking; Theophylline; Thiophenes | 2008 |
Switching to duloxetine from selective serotonin reuptake inhibitor antidepressants: a multicenter trial comparing 2 switching techniques.
Topics: Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2008 |
Duloxetine for premenstrual dysphoric disorder: a pilot study.
Topics: Adrenergic Uptake Inhibitors; Adult; Affect; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Depression; Duloxetine Hydrochloride; Female; Humans; Pilot Projects; Premenstrual Syndrome; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Time Factors; Treatment Outcome | 2008 |
The use of Duloxetine in the treatment of male stress urinary incontinence.
Topics: Adrenergic Uptake Inhibitors; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Drug Administration Schedule; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Patient Satisfaction; Postoperative Complications; Prostatectomy; Selective Serotonin Reuptake Inhibitors; Thiophenes; Transurethral Resection of Prostate; Urinary Incontinence, Stress | 2008 |
Early improvement during duloxetine treatment of generalized anxiety disorder predicts response and remission at endpoint.
Topics: Adult; Anxiety Disorders; Diagnostic and Statistical Manual of Mental Disorders; Duloxetine Hydrochloride; Endpoint Determination; Female; Humans; Male; Middle Aged; Prognosis; Psychiatric Status Rating Scales; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome | 2008 |
Efficacy of duloxetine for the treatment of depression: relationship to most recent antidepressant trial.
Topics: Adult; Antidepressive Agents; Depression; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes | 2008 |
Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: Results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial.
Topics: Adrenergic Uptake Inhibitors; Analgesics; Clinical Protocols; Clinical Trials as Topic; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Longitudinal Studies; Male; Middle Aged; Outcome Assessment, Health Care; Placebo Effect; Thiophenes; Treatment Outcome | 2008 |
Long-term efficacy of duloxetine in women with stress urinary incontinence.
Topics: Cohort Studies; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Patient Satisfaction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome; Urinary Incontinence, Stress | 2008 |
Treatment of seasonal affective disorder with duloxetine: an open-label study.
Topics: Adult; Antidepressive Agents; Disability Evaluation; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pilot Projects; Psychiatric Status Rating Scales; Retrospective Studies; Seasonal Affective Disorder; Thiophenes; Time Factors; Treatment Outcome | 2008 |
Improvement of psychic and somatic symptoms in adult patients with generalized anxiety disorder: examination from a duloxetine, venlafaxine extended-release and placebo-controlled trial.
Topics: Anxiety Disorders; Cyclohexanols; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Psychophysiologic Disorders; Psychotherapy; Surveys and Questionnaires; Thiophenes; Venlafaxine Hydrochloride; Young Adult | 2009 |
Efficacy and safety of duloxetine in elderly women with stress urinary incontinence or stress-predominant mixed urinary incontinence.
Topics: Aged; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Quality of Life; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2008 |
Duloxetine treatment for relapse prevention in adults with generalized anxiety disorder: a double-blind placebo-controlled trial.
Topics: Adult; Analysis of Variance; Antidepressive Agents; Anxiety Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Retrospective Studies; Secondary Prevention; Thiophenes; Time Factors | 2008 |
Effect of antidepressants on melatonin metabolite in depressed patients.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Hypericum; Male; Melatonin; Middle Aged; Plant Extracts; Severity of Illness Index; Thiophenes; Treatment Outcome | 2009 |
Dissociable effects of acute antidepressant drug administration on subjective and emotional processing measures in healthy volunteers.
Topics: Adult; Antidepressive Agents; Double-Blind Method; Duloxetine Hydrochloride; Electromyography; Emotions; Facial Expression; Female; Humans; Male; Memory; Mental Recall; Perception; Personality Tests; Psychomotor Performance; Reaction Time; Reflex, Startle; Serotonin; Social Perception; Thiophenes; Young Adult | 2008 |
Duloxetine for major depressive episodes in the course of psychotic disorders: an observational clinical trial.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Prospective Studies; Thiophenes | 2009 |
Predictors of relapse in a study of duloxetine treatment in patients with major depressive disorder.
Topics: Acute Disease; Adult; Antidepressive Agents; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Pain Measurement; Predictive Value of Tests; Prevalence; Prospective Studies; Recurrence; Severity of Illness Index; Thiophenes | 2009 |
The influence of smoking on the serum level of duloxetine.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Polycyclic Compounds; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Smoking; Thiophenes | 2008 |
The relationship between functional outcomes and the treatment of anxious and painful somatic symptoms in patients with generalized anxiety disorder.
Topics: Adult; Antidepressive Agents; Anxiety Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Pain Measurement; Placebos; Psychophysiologic Disorders; Thiophenes; Treatment Outcome | 2008 |
Switching to duloxetine in selective serotonin reuptake inhibitor non- and partial-responders: effects on painful physical symptoms of depression.
Topics: Activities of Daily Living; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Europe; Female; Health Surveys; Humans; Male; Middle Aged; Pain; Pain Measurement; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Surveys and Questionnaires; Thiophenes; Time Factors; Treatment Outcome | 2009 |
Efficacy and tolerability of duloxetine in the treatment of patients with borderline personality disorder: a pilot study.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Borderline Personality Disorder; Duloxetine Hydrochloride; Female; Headache; Humans; Male; Medication Adherence; Middle Aged; Nausea; Pilot Projects; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes | 2010 |
An assessment of drug-drug interactions: the effect of desvenlafaxine and duloxetine on the pharmacokinetics of the CYP2D6 probe desipramine in healthy subjects.
Topics: Adult; Antidepressive Agents; Area Under Curve; Biotransformation; Cross-Over Studies; Cyclohexanols; Cytochrome P-450 CYP2D6; Desipramine; Desvenlafaxine Succinate; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes | 2008 |
Escitalopram and duloxetine in major depressive disorder: a pharmacoeconomic comparison using UK cost data.
Topics: Absenteeism; Adolescent; Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Cost-Benefit Analysis; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Multivariate Analysis; Severity of Illness Index; Sick Leave; Surveys and Questionnaires; Thiophenes; United Kingdom; Young Adult | 2008 |
Is duloxetine effective treatment for depression with atypical features?
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Thiophenes; Time Factors; Treatment Outcome; Young Adult | 2008 |
Clinical milestones predict symptom remission over 6-month and choice of treatment of patients with major depressive disorder (MDD).
Topics: Adult; Analysis of Variance; Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Paroxetine; Patient Compliance; Predictive Value of Tests; Psychiatric Status Rating Scales; Remission Induction; Thiophenes; Treatment Outcome | 2009 |
A single-blind, placebo run-in study of duloxetine for activity-limiting osteoarthritis pain.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antidepressive Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Osteoarthritis; Pain; Pain Measurement; Single-Blind Method; Thiophenes; Time Factors; Treatment Outcome | 2009 |
Variation in catechol-O-methyltransferase is associated with duloxetine response in a clinical trial for major depressive disorder.
Topics: Adult; Catechol O-Methyltransferase; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Genome-Wide Association Study; Genotype; Humans; Male; Polymorphism, Single Nucleotide; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2009 |
Effects of selective serotonin reuptake and dual serotonergic-noradrenergic reuptake treatments on memory and mental processing speed in patients with major depressive disorder.
Topics: Adult; Analysis of Variance; Antidepressive Agents; Citalopram; Cognition; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Male; Memory; Neuropsychological Tests; Neurotransmitter Uptake Inhibitors; Psychiatric Status Rating Scales; Psychomotor Performance; Reaction Time; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thinking; Thiophenes | 2009 |
A continuous responder analysis from a long-term trial of duloxetine treatment for generalized anxiety disorder: implications for the randomized withdrawal relapse prevention study design.
Topics: Analysis of Variance; Antidepressive Agents; Anxiety Disorders; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Longitudinal Studies; Male; Middle Aged; Outpatients; Psychiatric Status Rating Scales; Research Design; Secondary Prevention; Thiophenes; Time Factors | 2009 |
Long-term safety, tolerability, and efficacy of duloxetine in the treatment of fibromyalgia.
Topics: Antidepressive Agents; Depression; Disability Evaluation; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Health Status; Humans; Male; Middle Aged; Pain; Pain Measurement; Thiophenes; Treatment Outcome | 2010 |
A randomized, double-blind study of increasing or maintaining duloxetine dose in patients without remission of major depressive disorder after initial duloxetine therapy.
Topics: Adolescent; Adult; Antidepressive Agents; Cohort Studies; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Personality Inventory; Prospective Studies; Psychometrics; Retreatment; Thiophenes; Treatment Outcome; Young Adult | 2008 |
An 8-week, open-label trial of duloxetine for comorbid major depressive disorder and chronic headache.
Topics: Adolescent; Adult; Antidepressive Agents; Brazil; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Headache Disorders; Humans; Male; Middle Aged; Pain Measurement; Personality Inventory; Prognosis; Quality of Life; Thiophenes | 2008 |
Early symptom change prediction of remission in depression treatment.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Predictive Value of Tests; Psychiatric Status Rating Scales; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome; Young Adult | 2009 |
Pilot study of augmentation with aripiprazole for incomplete response in late-life depression: getting to remission.
Topics: Aged; Aged, 80 and over; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Citalopram; Cyclohexanols; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Therapy, Combination; Duloxetine Hydrochloride; Feasibility Studies; Female; Humans; Male; Personality Inventory; Pilot Projects; Piperazines; Quinolones; Thiophenes; Venlafaxine Hydrochloride | 2009 |
Duloxetine treatment for women with premenstrual dysphoric disorder: a single-blind trial.
Topics: Adolescent; Adult; Antidepressive Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Pilot Projects; Premenstrual Syndrome; Psychiatric Status Rating Scales; Severity of Illness Index; Single-Blind Method; Thiophenes; Treatment Outcome; Young Adult | 2009 |
Effects of adjunctive reboxetine in patients with duloxetine-resistant depression: a 12-week prospective study.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Drug Resistance; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Morpholines; Psychiatric Status Rating Scales; Reboxetine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome; Young Adult | 2010 |
Extended release quetiapine fumarate monotherapy in major depressive disorder: a placebo- and duloxetine-controlled study.
Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Depressive Disorder, Major; Dibenzothiazepines; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Quetiapine Fumarate; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes | 2009 |
[Cymbalta in the treatment of chronic pain syndromes].
Topics: Adult; Antidepressive Agents; Chronic Disease; Depression; Duloxetine Hydrochloride; Follow-Up Studies; Humans; Middle Aged; Pain; Pain Measurement; Syndrome; Thiophenes; Treatment Outcome | 2009 |
Effectiveness of the psychological and pharmacological treatment of catastrophization in patients with fibromyalgia: a randomized controlled trial.
Topics: Adolescent; Adult; Aged; Analgesics; Antidepressive Agents; Cognitive Behavioral Therapy; Combined Modality Therapy; Depression; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain; Pain Management; Pain Measurement; Pregabalin; Psychiatric Status Rating Scales; Research Design; Spain; Thiophenes; Time Factors; Treatment Outcome; Young Adult | 2009 |
A 1-year safety and efficacy study of duloxetine in patients with fibromyalgia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Comorbidity; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Internationality; Male; Middle Aged; Pain; Pain Measurement; Thiophenes; Treatment Outcome; Young Adult | 2009 |
A double-blind, randomized trial of duloxetine versus placebo in the management of chronic low back pain.
Topics: Analysis of Variance; Chronic Disease; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Low Back Pain; Male; Middle Aged; Pain Measurement; Patient Selection; Quality of Life; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2009 |
Reductions in stress urinary incontinence episodes: what is clinically important for women?
Topics: Adult; Aged; Aged, 80 and over; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Patient Satisfaction; Quality of Life; Surveys and Questionnaires; Thiophenes; Urinary Incontinence, Stress; Young Adult | 2010 |
Duloxetine in obese binge eater outpatients: preliminary results from a 12-week open trial.
Topics: Adult; Bulimia; Depressive Disorder; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Obesity; Pilot Projects; Psychiatric Status Rating Scales; Psychometrics; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2009 |
Pharmacokinetics of duloxetine hydrochloride enteric-coated tablets in healthy Chinese volunteers: a randomized, open-label, single- and multiple-dose study.
Topics: Adult; Analysis of Variance; Antidepressive Agents; Area Under Curve; China; Chromatography, Liquid; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Male; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Tablets, Enteric-Coated; Tandem Mass Spectrometry; Thiophenes; Young Adult | 2009 |
Duloxetine in the treatment of irritable bowel syndrome: an open-label pilot study.
Topics: Adult; Analgesics; Antidepressive Agents; Disability Evaluation; Duloxetine Hydrochloride; Female; Humans; Irritable Bowel Syndrome; Male; Middle Aged; Pain Measurement; Pilot Projects; Quality of Life; Severity of Illness Index; Thiophenes; Treatment Outcome; Young Adult | 2009 |
Duloxetine in the prevention of depressive recurrences: a randomized, double-blind, placebo-controlled trial.
Topics: Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Prevalence; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Sex Distribution; Thiophenes | 2009 |
Duloxetine, a centrally acting analgesic, in the treatment of patients with osteoarthritis knee pain: a 13-week, randomized, placebo-controlled trial.
Topics: Aged; Analgesics; Antidepressive Agents; Depression; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Knee; Male; Middle Aged; Osteoarthritis; Pain; Pain Measurement; Psychiatric Status Rating Scales; Thiophenes; Treatment Outcome | 2009 |
Evaluating the maintenance of effect of duloxetine in patients with diabetic peripheral neuropathic pain.
Topics: Adrenergic Uptake Inhibitors; Aged; Confidence Intervals; Diabetic Neuropathies; Drug Monitoring; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Thiophenes; Time Factors; Treatment Outcome | 2009 |
Effects of duloxetine on the pharmacodynamics and pharmacokinetics of warfarin at steady state in healthy subjects.
Topics: Adult; Anticoagulants; Blood Coagulation Tests; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Isomerism; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Statistics as Topic; Thiophenes; Warfarin; Young Adult | 2009 |
Short- and long-term efficacy and safety of duloxetine in women with predominant stress urinary incontinence.
Topics: Adult; Aged; Algorithms; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Middle Aged; Placebos; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome; Urinary Incontinence, Stress | 2010 |
Effects of duloxetine in treatment-refractory men with posttraumatic stress disorder.
Topics: Combat Disorders; Comorbidity; Depressive Disorder, Major; Dreams; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Neurotransmitter Uptake Inhibitors; Psychiatric Status Rating Scales; Stress Disorders, Post-Traumatic; Thiophenes; Time Factors; Treatment Outcome; Veterans; Warfare | 2010 |
Failure to replicate genetic associations with antidepressant treatment response in duloxetine-treated patients.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Duloxetine Hydrochloride; Female; Genetic Association Studies; Genotype; Humans; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Thiophenes; Treatment Outcome | 2010 |
Urinary flow and urinary symptoms in elderly males exposed to either escitalopram or duloxetine.
Topics: Aged; Citalopram; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Pilot Projects; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urination; Urination Disorders | 2010 |
Duloxetine 60 mg/day for the prevention of depressive recurrences: post hoc analyses from a recurrence prevention study.
Topics: Adult; Aged; Analysis of Variance; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Secondary Prevention; Thiophenes; Treatment Outcome; Young Adult | 2010 |
Effects of varying degrees of renal impairment on the pharmacokinetics of duloxetine: analysis of a single-dose phase I study and pooled steady-state data from phase II/III trials.
Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Kidney Failure, Chronic; Male; Metabolic Clearance Rate; Middle Aged; Thiophenes | 2010 |
Escitalopram 20 mg versus duloxetine 60 mg for the treatment of chronic low back pain.
Topics: Adult; Aged; Chronic Disease; Citalopram; Duloxetine Hydrochloride; Female; Health Surveys; Humans; Low Back Pain; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Treatment Outcome | 2010 |
Efficacy and safety of duloxetine in patients with chronic low back pain.
Topics: Adult; Aged; Chronic Disease; Diarrhea; Double-Blind Method; Duloxetine Hydrochloride; Fatigue; Female; Humans; Low Back Pain; Male; Middle Aged; Nausea; Pain Measurement; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome | 2010 |
Duloxetine versus placebo in patients with chronic low back pain: a 12-week, fixed-dose, randomized, double-blind trial.
Topics: Chronic Disease; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Low Back Pain; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2010 |
Maintenance of effect of duloxetine in patients with chronic low back pain: a 41-week uncontrolled, dose-blinded study.
Topics: Adult; Aged; Analgesics; Antidepressive Agents; Chronic Disease; Clinical Protocols; Disability Evaluation; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Low Back Pain; Male; Middle Aged; Pain Measurement; Placebos; Severity of Illness Index; Surveys and Questionnaires; Thiophenes; Treatment Outcome | 2010 |
Duloxetine reduces morphine requirements after knee replacement surgery.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Double-Blind Method; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Care; Selective Serotonin Reuptake Inhibitors; Thiophenes; Young Adult | 2010 |
Duloxetine for the treatment of generalized social anxiety disorder: a preliminary randomized trial of increased dose to optimize response.
Topics: Anxiety Disorders; Double-Blind Method; Duloxetine Hydrochloride; Humans; Thiophenes; Treatment Outcome | 2010 |
Flexible dosed duloxetine in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Middle Aged; Placebos; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Treatment Outcome | 2010 |
Efficacy and safety of duloxetine 60 mg and 120 mg daily in patients hospitalized for severe depression: a double-blind randomized trial.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Hospitalization; Humans; Male; Middle Aged; Personality Inventory; Psychometrics; Suicidal Ideation; Thiophenes | 2011 |
Duloxetine versus venlafaxine in the treatment of unipolar and bipolar depression.
Topics: Adult; Antidepressive Agents; Bipolar Disorder; Cyclohexanols; Depressive Disorder; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Retrospective Studies; Thiophenes; Venlafaxine Hydrochloride | 2010 |
Duloxetine for mild to moderate postprostatectomy incontinence: preliminary results of a randomised, placebo-controlled trial.
Topics: Adrenergic Uptake Inhibitors; Aged; Aged, 80 and over; Chi-Square Distribution; Double-Blind Method; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Paris; Pilot Projects; Placebo Effect; Prospective Studies; Prostatectomy; Quality of Life; Selective Serotonin Reuptake Inhibitors; Surveys and Questionnaires; Thiophenes; Time Factors; Treatment Outcome; Urinary Incontinence | 2011 |
Attributes of response in depressed patients switched to treatment with duloxetine.
Topics: Adult; Affective Symptoms; Antidepressive Agents; Chronic Pain; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2011 |
Duloxetine in patients with central neuropathic pain caused by spinal cord injury or stroke: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Disability Evaluation; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Hyperalgesia; Male; Middle Aged; Neuralgia; Outcome Assessment, Health Care; Pain Measurement; Pain Threshold; Placebo Effect; Spinal Cord Injuries; Stroke; Thiophenes; Treatment Outcome | 2011 |
Sexual function during long-term duloxetine treatment in patients with recurrent major depressive disorder.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Male; Psychiatric Status Rating Scales; Sexual Behavior; Sexual Dysfunction, Physiological; Surveys and Questionnaires; Thiophenes | 2011 |
Assessing remission in major depressive disorder and generalized anxiety disorder clinical trials with the discan metric of the Sheehan disability scale.
Topics: Antidepressive Agents; Anxiety Disorders; Comorbidity; Depression; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Outpatients; Placebos; Psychiatric Status Rating Scales; Psychometrics; Thiophenes; Time Factors; Treatment Outcome | 2011 |
Duloxetine in military posttraumatic stress disorder.
Topics: Adult; Aged; Analysis of Variance; Antidepressive Agents; Duloxetine Hydrochloride; Humans; Male; Middle Aged; New Mexico; Prospective Studies; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Stress Disorders, Post-Traumatic; Thiophenes; Time Factors; Treatment Outcome; Veterans | 2010 |
Duloxetine versus placebo in the treatment of patients with diabetic neuropathic pain in China.
Topics: Adrenergic Uptake Inhibitors; Aged; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Placebos; Thiophenes; Treatment Outcome | 2010 |
Pseudohypoalgesia on the skin: a novel view on the paradox of pain perception in depression.
Topics: Adult; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Hot Temperature; Humans; Male; Middle Aged; Pain; Pain Measurement; Pain Perception; Pain Threshold; Skin Physiological Phenomena; Thiophenes | 2011 |
Subchronic duloxetine administration alters the extended amygdala circuitry in healthy individuals.
Topics: Adolescent; Adult; Amygdala; Antidepressive Agents; Brain Mapping; Cross-Over Studies; Double-Blind Method; Duloxetine Hydrochloride; Emotions; Facial Expression; Female; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male; Photic Stimulation; Thiophenes; Young Adult | 2011 |
An open, non-randomised comparison of escitalopram and duloxetine for the treatment of subjects with Generalized Anxiety Disorder.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Analysis of Variance; Anxiety Disorders; Citalopram; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Patient Dropouts; Personality Disorders; Psychiatric Status Rating Scales; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome; Young Adult | 2011 |
Estimation of minimum clinically important difference for pain in fibromyalgia.
Topics: Adult; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Pain; Pain Measurement; Severity of Illness Index; Thiophenes | 2011 |
A comparative evaluation of amitriptyline and duloxetine in painful diabetic neuropathy: a randomized, double-blind, cross-over clinical trial.
Topics: Adolescent; Adult; Aged; Amitriptyline; Cross-Over Studies; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes; Young Adult | 2011 |
Clinical and demographic predictors of improvement during duloxetine treatment in patients with major depression: an open-label study.
Topics: Adult; Antidepressive Agents; Anxiety; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes; Treatment Outcome | 2011 |
Remission of major depressive disorder without adverse events: a comparison of escitalopram versus serotonin norepinephrine reuptake inhibitors.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Citalopram; Cyclohexanols; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neurotransmitter Uptake Inhibitors; Norepinephrine; Remission Induction; Serotonin; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride; Young Adult | 2011 |
Two-week administration of the combined serotonin-noradrenaline reuptake inhibitor duloxetine augments functioning of mesolimbic incentive processing circuits.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Affect; Brain Mapping; Duloxetine Hydrochloride; Female; Humans; Limbic System; Magnetic Resonance Imaging; Male; Mesencephalon; Middle Aged; Motivation; Neural Pathways; Neuroimaging; Psychomotor Performance; Reward; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2011 |
Differential conditioned fear response predicts duloxetine treatment outcome in male veterans with PTSD: a pilot study.
Topics: Antidepressive Agents; Conditioning, Psychological; Duloxetine Hydrochloride; Fear; Humans; Male; Middle Aged; Multivariate Analysis; Pilot Projects; Stress Disorders, Post-Traumatic; Thiophenes; Veterans | 2011 |
Improvement in multiple dimensions of fatigue in patients with fibromyalgia treated with duloxetine: secondary analysis of a randomized, placebo-controlled trial.
Topics: Adult; Antidepressive Agents; Anxiety; Depression; Duloxetine Hydrochloride; Fatigue; Female; Fibromyalgia; Humans; Male; Middle Aged; Motor Activity; Musculoskeletal Pain; Pain Threshold; Patient Satisfaction; Placebos; Sleep Wake Disorders; Thiophenes; Treatment Outcome | 2011 |
Predictors of relapse in a study of duloxetine treatment for patients with generalized anxiety disorder.
Topics: Adult; Anxiety Disorders; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Predictive Value of Tests; Secondary Prevention; Thiophenes; Treatment Outcome | 2011 |
Clinical and functional outcomes in patients with major depressive disorder and painful physical symptoms switched to treatment with duloxetine.
Topics: Adult; Depressive Disorder, Major; Drug Substitution; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Pain Measurement; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2011 |
Pilot study of duloxetine for treatment of aromatase inhibitor-associated musculoskeletal symptoms.
Topics: Adult; Aged; Aromatase Inhibitors; Chronic Pain; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Musculoskeletal Diseases; Pain; Pilot Projects; Postmenopause; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2011 |
Sex differences in the effects of MDMA (ecstasy) on plasma copeptin in healthy subjects.
Topics: Adult; Arginine Vasopressin; Cross-Over Studies; Duloxetine Hydrochloride; Female; Glycopeptides; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Osmolar Concentration; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Sex Characteristics; Thiophenes | 2011 |
Duloxetine, pregabalin, and duloxetine plus gabapentin for diabetic peripheral neuropathic pain management in patients with inadequate pain response to gabapentin: an open-label, randomized, noninferiority comparison.
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Pregabalin; Thiophenes; Treatment Outcome | 2011 |
Duloxetine in the treatment of binge eating disorder with depressive disorders: a placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Binge-Eating Disorder; Depressive Disorder; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes; Treatment Outcome | 2012 |
Early improvement in pain predicts pain response at endpoint in patients with fibromyalgia.
Topics: Adult; Dopamine Uptake Inhibitors; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Pain; Pain Measurement; Predictive Value of Tests; Regression Analysis; Thiophenes; Time Factors | 2011 |
Short-term duloxetine administration affects neural correlates of mood-congruent memory.
Topics: Adolescent; Adult; Affect; Antidepressive Agents; Brain; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Memory; Middle Aged; Neurons; Photic Stimulation; Thiophenes; Young Adult | 2011 |
Duloxetine improves oxaliplatin-induced neuropathy in patients with colorectal cancer: an open-label pilot study.
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents; Antineoplastic Agents; Colorectal Neoplasms; Duloxetine Hydrochloride; Feasibility Studies; Female; Follow-Up Studies; Humans; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Pain Measurement; Peripheral Nervous System Diseases; Pilot Projects; Severity of Illness Index; Thiophenes | 2012 |
Duloxetine's modest short-term influences in subcortical structures of first episode drug-naïve patients with major depressive disorder and panic disorder.
Topics: Adult; Antidepressive Agents; Brain; Brain Mapping; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Middle Aged; Panic Disorder; Psychiatric Status Rating Scales; Statistics as Topic; Thiophenes | 2011 |
Duloxetine versus placebo in the treatment of major depressive disorder and associated painful physical symptoms: a replication study.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Pain; Puerto Rico; Remission Induction; Thiophenes; Time Factors; United States | 2011 |
A randomized placebo-controlled trial of duloxetine in patients with major depressive disorder and associated painful physical symptoms.
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Remission Induction; Thiophenes; Time Factors | 2011 |
A randomized, single-blind, comparison of duloxetine with bupropion in the treatment of SSRI-resistant major depression.
Topics: Adult; Antidepressive Agents; Bupropion; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Single-Blind Method; Thiophenes | 2012 |
Early reduction in painful physical symptoms is associated with improvements in long-term depression outcomes in patients treated with duloxetine.
Topics: Antidepressive Agents; Depression; Duloxetine Hydrochloride; Female; Humans; International Classification of Diseases; Male; Middle Aged; Outpatients; Pain; Pain Measurement; Prospective Studies; Severity of Illness Index; Thiophenes | 2011 |
Duloxetine as adjunctive treatment to clozapine in patients with schizophrenia: a randomized, placebo-controlled trial.
Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Antipsychotic Agents; Clozapine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Duloxetine Hydrochloride; Executive Function; Female; Guidelines as Topic; Humans; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome; Young Adult | 2011 |
[Biological age and the pain syndrome at diabetic polyneuropathy].
Topics: Adult; Aging; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Selective Serotonin Reuptake Inhibitors; Syndrome; Thiophenes; Treatment Outcome | 2011 |
Duloxetine added to oral nonsteroidal anti-inflammatory drugs for treatment of knee pain due to osteoarthritis: results of a randomized, double-blind, placebo-controlled trial.
Topics: Administration, Oral; Adrenergic Uptake Inhibitors; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Knee; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Management; Thiophenes; Time Factors | 2011 |
A pragmatic 12-week, randomized trial of duloxetine versus generic selective serotonin-reuptake inhibitors in the treatment of adult outpatients in a moderate-to-severe depressive episode.
Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Depressive Disorder, Major; Disability Evaluation; Drugs, Generic; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Outpatients; Prospective Studies; Psychiatric Status Rating Scales; Remission Induction; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Time Factors; Treatment Outcome; United States | 2012 |
Duloxetine versus placebo in the treatment of patients with generalized anxiety disorder in China.
Topics: Adult; Antidepressive Agents; Anxiety Disorders; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes; Treatment Outcome | 2011 |
Trajectories of depression severity in clinical trials of duloxetine: insights into antidepressant and placebo responses.
Topics: Adult; Antidepressive Agents; Data Interpretation, Statistical; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Linear Models; Male; Patient Dropouts; Placebo Effect; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Treatment Outcome | 2011 |
A randomised, double-blind, placebo controlled, duloxetine-referenced, fixed-dose study of three dosages of Lu AA21004 in acute treatment of major depressive disorder (MDD).
Topics: Aged; Analysis of Variance; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Logistic Models; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Reference Values; Sulfides; Thiophenes; Treatment Outcome; Vortioxetine | 2012 |
Assessment of depressive symptoms and functional outcomes in patients with major depressive disorder treated with duloxetine versus placebo: primary outcomes from two trials conducted under the same protocol.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Models, Statistical; Psychiatric Status Rating Scales; Recovery of Function; Thiophenes; Treatment Outcome | 2012 |
An open-label safety and pharmacokinetics study of duloxetine in pediatric patients with major depression.
Topics: Adolescent; Antidepressive Agents; Blood Pressure; Child; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Male; Psychiatric Status Rating Scales; Severity of Illness Index; Suicidal Ideation; Thiophenes; Treatment Outcome | 2012 |
Efficacy and safety of the α4β2 neuronal nicotinic receptor agonist ABT-894 in patients with diabetic peripheral neuropathic pain.
Topics: Aged; Azabicyclo Compounds; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neuralgia; Nicotinic Agonists; Pain Measurement; Pyridines; Receptors, Nicotinic; Thiophenes; Treatment Outcome | 2012 |
Apathy in currently nondepressed patients treated with a SSRI for a major depressive episode: outcomes following randomized switch to either duloxetine or escitalopram.
Topics: Adult; Aged; Analysis of Variance; Apathy; Citalopram; Cross-Sectional Studies; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Young Adult | 2012 |
Conditioned pain modulation predicts duloxetine efficacy in painful diabetic neuropathy.
Topics: Aged; Analgesics; Conditioning, Psychological; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neuralgia; Pain Threshold; Predictive Value of Tests; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2012 |
Early non-response in patients with severe depression: escitalopram up-titration versus switch to duloxetine.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Citalopram; Depression; Dopamine Uptake Inhibitors; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Severity of Illness Index; Thiophenes; Treatment Outcome; Young Adult | 2012 |
A randomized, double-blind, placebo-controlled, duloxetine-referenced, fixed-dose study comparing the efficacy and safety of Lu AA21004 in elderly patients with major depressive disorder.
Topics: Aged; Aged, 80 and over; Antidepressive Agents; Cognition Disorders; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Piperazines; Placebos; Psychiatric Status Rating Scales; Sulfides; Thiophenes; Vortioxetine | 2012 |
Duloxetine inhibits effects of MDMA ("ecstasy") in vitro and in humans in a randomized placebo-controlled laboratory study.
Topics: 3,4-Methylenedioxyamphetamine; Adult; Biological Transport; Duloxetine Hydrochloride; Female; Humans; Laboratories; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Placebo Effect; Receptors, Adrenergic; Serotonin; Serotonin Plasma Membrane Transport Proteins; Thiophenes | 2012 |
Duloxetine in adults with ADHD: a randomized, placebo-controlled pilot study.
Topics: Adolescent; Adult; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Personality Inventory; Pilot Projects; Psychiatric Status Rating Scales; Thiophenes; Treatment Outcome; Young Adult | 2014 |
Pilot study of duloxetine for cancer patients with neuropathic pain non-responsive to pregabalin.
Topics: Adult; Aged; Analgesics; Antidepressive Agents; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neoplasms; Neuralgia; Pilot Projects; Pregabalin; Thiophenes | 2012 |
Intensive monitoring of duloxetine: results of a web-based intensive monitoring study.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder; Drug Monitoring; Duloxetine Hydrochloride; Female; Humans; Internet; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Surveys and Questionnaires; Thiophenes; Young Adult | 2013 |
Hippocampal N-acetylaspartate and morning cortisol levels in drug-naive, first-episode patients with major depressive disorder: effects of treatment.
Topics: Adolescent; Adult; Antidepressive Agents; Aspartic Acid; Case-Control Studies; Choline; Creatine; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Hippocampus; Humans; Hydrocortisone; Magnetic Resonance Spectroscopy; Male; Middle Aged; Thiophenes; Young Adult | 2012 |
Early switch strategy in patients with major depressive disorder: a double-blind, randomized study.
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents; Citalopram; Depressive Disorder, Treatment-Resistant; Double-Blind Method; Drug Administration Schedule; Drug Resistance; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Thiophenes | 2012 |
Evaluation of genetic models for response in a randomized clinical trial of duloxetine in major depressive disorder.
Topics: Adult; Antidepressive Agents; Catechol O-Methyltransferase; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Models, Genetic; Norepinephrine Plasma Membrane Transport Proteins; Polymorphism, Single Nucleotide; Receptor, Serotonin, 5-HT1A; Surveys and Questionnaires; Thiophenes; Treatment Outcome | 2012 |
Duloxetine for the management of pain in older adults with knee osteoarthritis: randomised placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Arthralgia; Disease Management; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Knee Joint; Male; Osteoarthritis, Knee; Outcome Assessment, Health Care; Pain Measurement; Quality of Life; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2012 |
Predictors of remission in depression to individual and combined treatments (PReDICT): study protocol for a randomized controlled trial.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; Biomarkers; Brain; Citalopram; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Genetic Testing; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Personality; Predictive Value of Tests; Remission Induction; Research Design; Thiophenes; Treatment Outcome; Young Adult | 2012 |
Early vs. conventional switching of antidepressants in patients with MDD and moderate to severe pain: a double-blind randomized study.
Topics: Activities of Daily Living; Adult; Aged; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Double-Blind Method; Drug Substitution; Duloxetine Hydrochloride; Female; Humans; Induction Chemotherapy; Male; Middle Aged; Pain; Pain Measurement; Thiophenes; Treatment Outcome; Young Adult | 2012 |
Population pharmacokinetic/pharmacodynamic models for duloxetine in the treatment of diabetic peripheral neuropathic pain.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Analgesics; Diabetic Neuropathies; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Logistic Models; Male; Middle Aged; Models, Statistical; Nonlinear Dynamics; Pain Measurement; Patient Dropouts; Sex Factors; Socioeconomic Factors; Thiophenes; Young Adult | 2013 |
A randomized controlled trial of duloxetine versus placebo in the treatment of nonmajor chronic depression.
Topics: Adult; Aged; Antidepressive Agents; Chronic Disease; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Dysthymic Disorder; Female; Humans; Male; Middle Aged; Personality Inventory; Prospective Studies; Psychometrics; Social Adjustment; Temperament; Thiophenes; Young Adult | 2012 |
Randomized, placebo-controlled comparison of amitriptyline, duloxetine, and pregabalin in patients with chronic diabetic peripheral neuropathic pain: impact on pain, polysomnographic sleep, daytime functioning, and quality of life.
Topics: Aged; Amitriptyline; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pregabalin; Quality of Life; Sleep; Thiophenes; Treatment Outcome | 2012 |
Duloxetine versus citalopram and sertraline in the treatment of poststroke depression, anxiety, and fatigue.
Topics: Activities of Daily Living; Adult; Aged; Antidepressive Agents; Anxiety; Citalopram; Depression; Duloxetine Hydrochloride; Fatigue; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Sertraline; Stroke; Thiophenes; Time Factors; Treatment Outcome; Young Adult | 2012 |
A 9-week randomized trial comparing a chronotherapeutic intervention (wake and light therapy) to exercise in major depressive disorder patients treated with duloxetine.
Topics: Adult; Aged; Antidepressive Agents; Combined Modality Therapy; Denmark; Depressive Disorder, Major; Duloxetine Hydrochloride; Exercise; Female; Humans; Logistic Models; Male; Middle Aged; Phototherapy; Prospective Studies; Seasons; Single-Blind Method; Sleep Phase Chronotherapy; Thiophenes | 2012 |
A non-comparative assessment of tolerability and efficacy of duloxetine in the treatment of depressed patients with Parkinson's disease.
Topics: Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Parkinson Disease; Psychiatric Status Rating Scales; Quality of Life; Thiophenes; Treatment Outcome | 2012 |
Depression treatment selectively modifies arterial stiffness in older participants.
Topics: Aged; Aging; Antidepressive Agents; Antidepressive Agents, Second-Generation; Blood Pressure; Cardiovascular Diseases; Cholesterol, LDL; Citalopram; Depression; Duloxetine Hydrochloride; Follow-Up Studies; Humans; Pulse Wave Analysis; Thiophenes; Treatment Outcome; Vascular Stiffness | 2013 |
A randomized, double-blind trial of 2.5 mg and 5 mg vortioxetine (Lu AA21004) versus placebo for 8 weeks in adults with major depressive disorder.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Piperazines; Placebos; Sexual Dysfunction, Physiological; Suicidal Ideation; Sulfides; Thiophenes; Treatment Outcome; Vortioxetine | 2013 |
Brain-derived neurotrophic factor in generalized anxiety disorder: results from a duloxetine clinical trial.
Topics: Adolescent; Adult; Aged; Agoraphobia; Analysis of Variance; Antidepressive Agents; Anxiety Disorders; Brain-Derived Neurotrophic Factor; China; Diagnostic and Statistical Manual of Mental Disorders; Disability Evaluation; Double-Blind Method; Duloxetine Hydrochloride; Endpoint Determination; Female; Humans; Male; Middle Aged; Panic Disorder; Phobic Disorders; Psychiatric Status Rating Scales; Stress, Psychological; Thiophenes; Treatment Outcome; Young Adult | 2013 |
Antidepressants normalize the default mode network in patients with dysthymia.
Topics: Adult; Antidepressive Agents; Brain; Case-Control Studies; Double-Blind Method; Duloxetine Hydrochloride; Dysthymic Disorder; Female; Functional Neuroimaging; Humans; Magnetic Resonance Imaging; Male; Nerve Net; Thiophenes | 2013 |
Evaluation of the effects of duloxetine and escitalopram on 24-hour heart rate variability: a mechanistic study using heart rate variability as a pharmacodynamic measure.
Topics: Adrenergic Uptake Inhibitors; Aged; Citalopram; Cross-Over Studies; Duloxetine Hydrochloride; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Single-Blind Method; Thiophenes | 2013 |
Comparison of safety outcomes among Caucasian, Hispanic, Black, and Asian patients in duloxetine studies of chronic painful conditions.
Topics: Adolescent; Adult; Analgesics; Asian; Black or African American; Chronic Pain; Duloxetine Hydrochloride; Female; Hispanic or Latino; Humans; Male; Middle Aged; Thiophenes; White People | 2013 |
Responsiveness of the Intermittent and Constant Osteoarthritis Pain (ICOAP) scale in a trial of duloxetine for treatment of osteoarthritis knee pain.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Thiophenes; Treatment Outcome | 2013 |
NGF serum levels variations in major depressed patients receiving duloxetine.
Topics: Adaptation, Psychological; Adult; Biomarkers; Depressive Disorder, Major; Drug Resistance; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Nerve Growth Factor; Neuronal Plasticity; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Stress, Psychological; Sympathomimetics; Thiophenes; Time Factors; Treatment Outcome | 2013 |
Prophylactic effects of duloxetine on post-stroke depression symptoms: an open single-blind trial.
Topics: Aged; Antidepressive Agents; Depression; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Single-Blind Method; Stroke; Thiophenes | 2013 |
Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neoplasms; Neuralgia; Peripheral Nervous System Diseases; Quality of Life; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2013 |
Experience and challenges presented by a multicenter crossover study of combination analgesic therapy for the treatment of painful HIV-associated polyneuropathies.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Comorbidity; Cross-Over Studies; Double-Blind Method; Drug Combinations; Duloxetine Hydrochloride; Female; HIV Infections; Humans; Male; Methadone; Middle Aged; Pain Measurement; Patient Selection; Polyneuropathies; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Failure; Treatment Outcome; Young Adult | 2013 |
Baseline patient characteristics associated with placebo remission and their impact on remission with duloxetine and selected SSRI antidepressants.
Topics: Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Placebo Effect; Placebos; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2013 |
Safety and efficacy of duloxetine treatment in older and younger patients with osteoarthritis knee pain: a post hoc, subgroup analysis of two randomized, placebo-controlled trials.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analgesics; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Thiophenes; Treatment Outcome | 2013 |
Duloxetine for major depressive disorder and daytime and nighttime hot flashes associated with the menopausal transition.
Topics: Antidepressive Agents; Anxiety; Anxiety Disorders; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Hot Flashes; Humans; Menopause; Middle Aged; Patient Selection; Severity of Illness Index; Thiophenes | 2013 |
Outcome of patients with chronic migraine with medication overuse and depression after duloxetine: influence of coexisting obsessive compulsive disorder.
Topics: Adult; Aged; Analgesics; Depression; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Migraine Disorders; Obsessive-Compulsive Disorder; Substance-Related Disorders; Thiophenes; Treatment Outcome; Young Adult | 2013 |
Effectiveness and cost-effectiveness of transmural collaborative care with consultation letter (TCCCL) and duloxetine for major depressive disorder (MDD) and (sub)chronic pain in collaboration with primary care: design of a randomized placebo-controlled m
Topics: Adaptation, Psychological; Antidepressive Agents; Chronic Pain; Cost-Benefit Analysis; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Patient Care Team; Primary Health Care; Quality of Life; Referral and Consultation; Research Design; Self Care; Thiophenes | 2013 |
Duloxetine and pregabalin: high-dose monotherapy or their combination? The "COMBO-DN study"--a multinational, randomized, double-blind, parallel-group study in patients with diabetic peripheral neuropathic pain.
Topics: Aged; Analgesics; Diabetic Neuropathies; Double-Blind Method; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Internationality; Male; Middle Aged; Pain; Pregabalin; Thiophenes; Treatment Outcome | 2013 |
Duloxetine use in chronic painful conditions--individual patient data responder analysis.
Topics: Antidepressive Agents; Chronic Pain; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Fibromyalgia; Humans; Individuality; Low Back Pain; Osteoarthritis; Pain Measurement; Thiophenes; Treatment Outcome | 2014 |
A comparison of duloxetine plasma levels in postbariatric surgery patients versus matched nonsurgical control subjects.
Topics: Administration, Oral; Adult; Antidepressive Agents; Area Under Curve; Duloxetine Hydrochloride; Female; Gastric Bypass; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; North Dakota; Thiophenes | 2013 |
Utilization of duloxetine and celecoxib in osteoarthritis patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Celecoxib; Cyclooxygenase 2 Inhibitors; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Osteoarthritis; Pyrazoles; Retrospective Studies; Sulfonamides; Thiophenes | 2013 |
Relationship between major depressive disorder and associated painful physical symptoms: analysis of data from two pooled placebo-controlled, randomized studies of duloxetine.
Topics: Adult; Analgesics; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Statistics as Topic; Thiophenes | 2013 |
[Impact of duloxetine on depression and anxiety in patients with ankylosing spondylitis: a case-control study].
Topics: Adult; Analgesics; Antidepressive Agents; Anxiety; Depression; Duloxetine Hydrochloride; Female; Humans; Male; Pain; Spondylitis, Ankylosing; Thiophenes; Young Adult | 2013 |
An open-label trial of duloxetine in patients with irritable bowel syndrome and comorbid generalized anxiety disorder.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anxiety Disorders; Comorbidity; Duloxetine Hydrochloride; Female; Humans; Irritable Bowel Syndrome; Male; Middle Aged; Outcome Assessment, Health Care; Pilot Projects; Placebos; Quality of Life; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Single-Blind Method; Thiophenes; Young Adult | 2014 |
A randomized, double-blind, placebo-controlled trial of duloxetine for the treatment of pain in patients with multiple sclerosis.
Topics: Adolescent; Adult; Analgesics; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Pain; Thiophenes; Treatment Outcome | 2014 |
Prescribing patterns of duloxetine in France: a prescription assessment study in real-world conditions.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Anxiety Disorders; Contraindications; Depressive Disorder, Major; Drug Utilization; Duloxetine Hydrochloride; Female; France; Humans; Male; Middle Aged; Thiophenes | 2014 |
Safety, tolerability, and efficacy of vortioxetine (Lu AA21004) in major depressive disorder: results of an open-label, flexible-dose, 52-week extension study.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Anxiety; Depression; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Sexual Dysfunction, Physiological; Suicidal Ideation; Sulfides; Thiophenes; Treatment Outcome; Vortioxetine; Weight Gain; Young Adult | 2014 |
The efficacy and safety of duloxetine in a multidrug regimen for chronic prostatitis/chronic pelvic pain syndrome.
Topics: Analgesics; Combined Modality Therapy; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Prospective Studies; Prostatitis; Thiophenes | 2014 |
Efficacy and safety of vortioxetine (Lu AA21004), 15 and 20 mg/day: a randomized, double-blind, placebo-controlled, duloxetine-referenced study in the acute treatment of adult patients with major depressive disorder.
Topics: Adolescent; Adult; Aged; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Headache; Humans; Internationality; Male; Middle Aged; Nausea; Piperazines; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Sulfides; Thiophenes; Treatment Outcome; Vortioxetine; Young Adult | 2014 |
Acute and long-term treatment of late-life major depressive disorder: duloxetine versus placebo.
Topics: Age of Onset; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Pain; Psychiatric Status Rating Scales; Thiophenes | 2014 |
A randomised, double-blind, placebo-controlled, duloxetine-referenced study of the efficacy and tolerability of vortioxetine in the acute treatment of adults with generalised anxiety disorder.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Piperazines; Sulfides; Thiophenes; Treatment Outcome; Vortioxetine; Young Adult | 2014 |
Effects of duloxetine on norepinephrine and serotonin transporter activity in healthy subjects.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; California; Central Nervous System; Citalopram; Cross-Over Studies; Duloxetine Hydrochloride; Female; Healthy Volunteers; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Texas; Thiophenes; Young Adult | 2014 |
Effectiveness of group acceptance and commitment therapy for fibromyalgia: a 6-month randomized controlled trial (EFFIGACT study).
Topics: Acceptance and Commitment Therapy; Adolescent; Adult; Aged; Analgesics; Catastrophization; Duloxetine Hydrochloride; Female; Fibromyalgia; Follow-Up Studies; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Patient Compliance; Pregabalin; Psychiatric Status Rating Scales; Surveys and Questionnaires; Thiophenes; Treatment Outcome; Young Adult | 2014 |
How does direct to consumer advertising affect the stigma of mental illness?
Topics: Adult; Advertising; Attitude to Health; Depression; Duloxetine Hydrochloride; Female; Humans; Male; Mental Disorders; Psychotropic Drugs; Stereotyping; Surveys and Questionnaires; Thiophenes | 2014 |
High baseline BDNF serum levels and early psychopathological improvement are predictive of treatment outcome in major depression.
Topics: Adult; Antidepressive Agents; Blood Chemical Analysis; Brain-Derived Neurotrophic Factor; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Prognosis; Prospective Studies; Psychiatric Status Rating Scales; Switzerland; Thiophenes; Time Factors; Treatment Outcome | 2014 |
Efficacy and safety of duloxetine in the treatment of older adult patients with generalized anxiety disorder: a randomized, double-blind, placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Antidepressive Agents; Anxiety Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2014 |
A double-blind efficacy and safety study of duloxetine flexible dosing in children and adolescents with major depressive disorder.
Topics: Adolescent; Antidepressive Agents; Child; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Suicidal Ideation; Suicide; Thiophenes; Treatment Outcome | 2014 |
A double-blind efficacy and safety study of duloxetine fixed doses in children and adolescents with major depressive disorder.
Topics: Adolescent; Antidepressive Agents; Child; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Suicidal Ideation; Suicide; Thiophenes; Treatment Outcome | 2014 |
Duloxetine-bupropion combination for treatment-resistant atypical depression: a double-blind, randomized, placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Bupropion; Depression; Double-Blind Method; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Thiophenes; Young Adult | 2014 |
Effects of olanzapine-fluoxetine combination treatment of major depressive disorders on the quality of life during acute treatment period.
Topics: Adult; Benzodiazepines; Depressive Disorder, Major; Drug Administration Schedule; Drug Combinations; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Quality of Life; Sleep Wake Disorders; Somatoform Disorders; Thiophenes | 2014 |
Cost-utility of cognitive behavioral therapy versus U.S. Food and Drug Administration recommended drugs and usual care in the treatment of patients with fibromyalgia: an economic evaluation alongside a 6-month randomized controlled trial.
Topics: Adult; Analgesics; Cognitive Behavioral Therapy; Cost-Benefit Analysis; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Fibromyalgia; gamma-Aminobutyric Acid; Health Care Costs; Humans; Male; Middle Aged; Pregabalin; Quality of Life; Quality-Adjusted Life Years; Surveys and Questionnaires; Thiophenes; Time Factors; Treatment Outcome; United States; United States Food and Drug Administration | 2014 |
Typology of patients with fibromyalgia: cluster analysis of duloxetine study patients.
Topics: Adult; Analgesics; Cluster Analysis; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Thiophenes | 2014 |
Duloxetine, dual serotonin and norepinephrine reuptake inhibitor, versus paroxetine, selective serotonin reuptake inhibitor, in the treatment for premature ejaculation.
Topics: Adult; Duloxetine Hydrochloride; Humans; Interpersonal Relations; Male; Paroxetine; Premature Ejaculation; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Surveys and Questionnaires; Thiophenes | 2015 |
Open-label study of duloxetine for the treatment of obsessive-compulsive disorder.
Topics: Adolescent; Adult; Anxiety; Depression; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neurotransmitter Uptake Inhibitors; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Psychotropic Drugs; Quality of Life; Thiophenes; Treatment Outcome; Young Adult | 2015 |
Efficacy and safety of the noradrenaline reuptake inhibitor, TAS-303, in women with stress urinary incontinence: Results of a double-blind, randomized, placebo-controlled, early phase II trial.
Topics: Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Norepinephrine; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2021 |
593 other study(ies) available for duloxetine hydrochloride and thiophenes
| Article | Year |
|---|---|
LY227942, an inhibitor of serotonin and norepinephrine uptake: biochemical pharmacology of a potential antidepressant drug.
Topics: Animals; Antidepressive Agents; Binding, Competitive; Biological Transport; Brain; Dopamine Antagonists; Duloxetine Hydrochloride; Kinetics; Norepinephrine; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Serotonin; Synaptosomes; Thiophenes | 1988 |
Effects of duloxetine, an antidepressant drug candidate, on concentrations of monoamines and their metabolites in rats and mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antidepressive Agents; Biogenic Monoamines; Brain; Dopamine; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred ICR; Monoamine Oxidase Inhibitors; Neurotransmitter Uptake Inhibitors; Norepinephrine; Oxidopamine; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Serotonin; Thiophenes | 1994 |
Simultaneous increases of extracellular monoamines in microdialysates from hypothalamus of conscious rats by duloxetine, a dual serotonin and norepinephrine uptake inhibitor.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Uptake Inhibitors; Animals; Biogenic Monoamines; Blood Platelets; Dopamine; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hypothalamus; In Vitro Techniques; Male; Microdialysis; Norepinephrine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptosomes; Thiophenes | 1995 |
Effects of duloxetine, a combined serotonin and norepinephrine reuptake inhibitor, on central neural control of lower urinary tract function in the chloralose-anesthetized female cat.
Topics: Acetates; Acetic Acid; Adrenergic Uptake Inhibitors; Anesthesia; Animals; Brain; Chick Embryo; Chloralose; Duloxetine Hydrochloride; Electromyography; Ergolines; Female; Muscle Contraction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Bladder | 1995 |
Effects of duloxetine, a new serotonin and norepinephrine uptake inhibitor, on extracellular monoamine levels in rat frontal cortex.
Topics: Amitriptyline; Animals; Biological Transport; Cerebral Cortex; Dopamine; Duloxetine Hydrochloride; Male; Maprotiline; Norepinephrine; Nucleus Accumbens; Rats; Rats, Wistar; Serotonin; Thiophenes | 1995 |
Behavioral and electroencephalographic properties of duloxetine (LY248686), a reuptake inhibitor of norepinephrine and serotonin, in mice and rats.
Topics: 5-Hydroxytryptophan; Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Body Temperature Regulation; Duloxetine Hydrochloride; Electroencephalography; Eyelids; Male; Maprotiline; Mice; Rats; Rats, Wistar; Salivation; Selective Serotonin Reuptake Inhibitors; Tears; Thiophenes; Tremor | 1995 |
LY248686, a new inhibitor of serotonin and norepinephrine uptake.
Topics: Animals; Antidepressive Agents; Appetite Regulation; Blood Platelets; Brain; Chromatography, High Pressure Liquid; Duloxetine Hydrochloride; Humans; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Thiophenes | 1993 |
Antagonism of serotonin 5-HT1A receptors potentiates the increases in extracellular monoamines induced by duloxetine in rat hypothalamus.
Topics: Animals; Biogenic Monoamines; Cyclohexylamines; Drug Synergism; Duloxetine Hydrochloride; Extracellular Space; Hypothalamus; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Thiophenes | 1996 |
Blockade of the serotonin and norepinephrine uptake processes by duloxetine: in vitro and in vivo studies in the rat brain.
Topics: Adrenergic Uptake Inhibitors; Animals; Brain; Duloxetine Hydrochloride; In Vitro Techniques; Iontophoresis; Locus Coeruleus; Male; Norepinephrine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes | 1996 |
Long-lasting inhibition of 5-HT uptake of platelets in subjects treated by duloxetine, a potential antidepressant.
Topics: Adult; Antidepressive Agents; Blood Platelets; Cells, Cultured; Depression, Chemical; Duloxetine Hydrochloride; Humans; Male; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes | 1996 |
Buspirone enhances duloxetine- and fluoxetine-induced increases in dialysate levels of dopamine and noradrenaline, but not serotonin, in the frontal cortex of freely moving rats.
Topics: Animals; Buspirone; Dopamine; Duloxetine Hydrochloride; Fluoxetine; Frontal Lobe; Male; Microdialysis; Norepinephrine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Thiophenes | 1997 |
Electrophysiological effects of fluoxetine and duloxetine in the dorsal raphe nucleus and hippocampus.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Electrophysiology; Fluoxetine; Hippocampus; Infusions, Intravenous; Iontophoresis; Male; Neurons; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Thiophenes | 1997 |
Designing a new generation of antidepressant drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cyclohexanols; Cyclopropanes; Drug Design; Duloxetine Hydrochloride; Humans; Mianserin; Milnacipran; Mirtazapine; Monoamine Oxidase Inhibitors; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Thiophenes; Venlafaxine Hydrochloride | 1997 |
Electrophysiological study of the effects of the reuptake inhibitor duloxetine on serotonergic responses in the aging hippocampus.
Topics: Action Potentials; Aging; Animals; Antidepressive Agents, Second-Generation; Desipramine; Duloxetine Hydrochloride; Female; Hippocampus; Iontophoresis; Rats; Rats, Inbred F344; Selective Serotonin Reuptake Inhibitors; Thiophenes | 1997 |
Alpha2-adrenergic receptor blockade markedly potentiates duloxetine- and fluoxetine-induced increases in noradrenaline, dopamine, and serotonin levels in the frontal cortex of freely moving rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Biogenic Monoamines; Dopamine; Duloxetine Hydrochloride; Fluoxetine; Frontal Lobe; Male; Norepinephrine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes | 1997 |
Firing frequency modulation of substantia nigra reticulata neurons by 5-hydroxytryptamine.
Topics: Animals; Benzimidazoles; Bicuculline; Brain Mapping; Bridged Bicyclo Compounds, Heterocyclic; Cell Survival; Duloxetine Hydrochloride; Electrophysiology; Evoked Potentials; In Vitro Techniques; Male; Methiothepin; Methysergide; Neurons; Rats; Rats, Wistar; Receptors, Serotonin; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Substantia Nigra; Thiophenes | 1997 |
Characterization of impurities formed by interaction of duloxetine HCl with enteric polymers hydroxypropyl methylcellulose acetate succinate and hydroxypropyl methylcellulose phthalate.
Topics: Adrenergic Uptake Inhibitors; Chromatography, High Pressure Liquid; Drug Contamination; Drug Stability; Duloxetine Hydrochloride; Methylcellulose; Selective Serotonin Reuptake Inhibitors; Spectrophotometry, Ultraviolet; Tablets, Enteric-Coated; Thiophenes | 1998 |
WAY 100,635 enhances both the 'antidepressant' actions of duloxetine and its influence on dialysate levels of serotonin in frontal cortex.
Topics: Animals; Antidepressive Agents; Cerebral Cortex; Drug Synergism; Duloxetine Hydrochloride; Frontal Lobe; Male; Piperazines; Pyridines; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Thiophenes | 1998 |
Antidepressant behavioral effects by dual inhibition of monoamine reuptake in the rat forced swimming test.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bupropion; Cyclopropanes; Desipramine; Duloxetine Hydrochloride; Fluoxetine; Male; Milnacipran; Motor Activity; Rats; Rats, Sprague-Dawley; Thiophenes | 1998 |
Electrophysiological characterization of the effect of long-term duloxetine administration on the rat serotonergic and noradrenergic systems.
Topics: Adrenergic Uptake Inhibitors; Animals; Carrier Proteins; Clonidine; Duloxetine Hydrochloride; Hippocampus; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters; Thiophenes | 1998 |
Effects of washing procedure on platelets pretreated with serotonin uptake inhibitors in vitro: low Ki values predict long-lasting inhibition of serotonin uptake in vivo.
Topics: Antidepressive Agents; Binding Sites; Blood Platelets; Cells, Cultured; Clomipramine; Depression, Chemical; Duloxetine Hydrochloride; Humans; Paroxetine; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes | 1998 |
Effect of long-term administration of duloxetine on the function of serotonin and noradrenaline terminals in the rat brain.
Topics: Animals; Brain; Brain Chemistry; Carrier Proteins; Duloxetine Hydrochloride; Electrophysiology; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Presynaptic Terminals; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters; Thiophenes | 1998 |
International group seeks to dispel incontinence "taboo".
Topics: Adrenergic Uptake Inhibitors; Aged; Consensus Development Conferences as Topic; Duloxetine Hydrochloride; Female; Humans; Male; Practice Guidelines as Topic; Quality of Life; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence; World Health Organization | 1998 |
Cellular electrophysiological effects of chronic fluoxetine and duloxetine administration on serotonergic responses in the aging hippocampus.
Topics: Aging; Animals; Antidepressive Agents; Drug Administration Schedule; Duloxetine Hydrochloride; Electrophysiology; Evoked Potentials; Female; Fluoxetine; Hippocampus; Pyramidal Cells; Rats; Rats, Inbred F344; Serotonin; Thiophenes | 1998 |
Chemo-enzymatic synthesis of the antidepressant duloxetine and its enantiomer.
Topics: Antidepressive Agents; Candida; Duloxetine Hydrochloride; Kinetics; Lipase; Saccharomyces cerevisiae; Stereoisomerism; Thiophenes | 2000 |
Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors.
Topics: Animals; Biogenic Monoamines; Carrier Proteins; Cell Line; Cyclohexanols; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Monoamine Oxidase; Nerve Tissue Proteins; Neurons; Norepinephrine Plasma Membrane Transport Proteins; Oxidopamine; p-Chloroamphetamine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Sympatholytics; Symporters; Thiophenes; Venlafaxine Hydrochloride | 2001 |
Comparison of the effects of serotonin selective, norepinephrine selective, and dual serotonin and norepinephrine reuptake inhibitors on lower urinary tract function in cats.
Topics: Acetic Acid; Administration, Intravesical; Adrenergic Uptake Inhibitors; Animals; Cats; Cyclohexanols; Duloxetine Hydrochloride; Electromyography; Female; Fluoxetine; Humans; Methiothepin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Thiophenes; Urethra; Urinary Bladder; Venlafaxine Hydrochloride | 2002 |
Comparison of the thermogenic and hypophagic effects of sibutramine's metabolite 2 and other monoamine reuptake inhibitors.
Topics: Animals; Body Temperature; Body Temperature Regulation; Bupropion; Conditioning, Operant; Cyclobutanes; Duloxetine Hydrochloride; Eating; Female; Hot Temperature; Neurotransmitter Uptake Inhibitors; Oxygen Consumption; Rats; Rats, Wistar; Serotonin; Thiophenes | 2002 |
[Depression also effects the body].
Topics: Antidepressive Agents, Second-Generation; Depressive Disorder; Duloxetine Hydrochloride; Humans; Randomized Controlled Trials as Topic; Thiophenes | 2003 |
Analgesic effects of antidepressants.
Topics: Analgesics; Antidepressive Agents; Chronic Disease; Depressive Disorder; Duloxetine Hydrochloride; Evidence-Based Medicine; Humans; Pain; Review Literature as Topic; Thiophenes | 2003 |
Duloxetine is both an inhibitor and a substrate of cytochrome P4502D6 in healthy volunteers.
Topics: Adult; Antidepressive Agents, Tricyclic; Area Under Curve; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Desipramine; Drug Administration Schedule; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Paroxetine; Reference Values; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2003 |
Duloxetine for the treatment of major depressive disorder.
Topics: Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Thiophenes; Treatment Outcome | 2002 |
Metabolism, excretion, and pharmacokinetics of duloxetine in healthy human subjects.
Topics: Administration, Oral; Adrenergic Uptake Inhibitors; Adult; Area Under Curve; Breath Tests; Duloxetine Hydrochloride; Feces; Female; Half-Life; Humans; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Middle Aged; Oxidation-Reduction; Selective Serotonin Reuptake Inhibitors; Tablets, Enteric-Coated; Thiophenes; Time Factors | 2003 |
Comparison of effects of dual transporter inhibitors on monoamine transporters and extracellular levels in rats.
Topics: Adrenergic Uptake Inhibitors; alpha-Methyltyrosine; Animals; Biogenic Monoamines; Brain Chemistry; Carrier Proteins; Clomipramine; Cyclohexanols; Cyclopropanes; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Extracellular Space; In Vitro Techniques; Male; Microdialysis; Milnacipran; Norepinephrine; p-Chloroamphetamine; Prefrontal Cortex; Radioligand Assay; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Thiophenes; Venlafaxine Hydrochloride | 2003 |
Duloxetine (Cymbalta), a dual inhibitor of serotonin and norepinephrine reuptake.
Topics: Antidepressive Agents; Binding Sites; Clinical Trials as Topic; Depressive Disorder; Duloxetine Hydrochloride; Humans; Kinetics; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Thiophenes | 2003 |
A word of caution about the implied role for duloxetine in pain management.
Topics: Antidepressive Agents; Comorbidity; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Pain; Pain Measurement; Somatoform Disorders; Thiophenes; Treatment Outcome | 2003 |
Milnacipran: a comparative analysis of human monoamine uptake and transporter binding affinity.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Carrier Proteins; Citalopram; Cyclohexanols; Cyclopropanes; Duloxetine Hydrochloride; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Mental Disorders; Milnacipran; Nerve Tissue Proteins; Neurons; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters; Thiophenes; Venlafaxine Hydrochloride | 2004 |
[18 million sick days due to depressive illnesses. New prospects in therapy of depression].
Topics: Absenteeism; Antidepressive Agents; Clinical Trials as Topic; Cross-Sectional Studies; Depressive Disorder; Diagnosis, Differential; Duloxetine Hydrochloride; Germany; Humans; Nursing Diagnosis; Somatoform Disorders; Thiophenes | 2003 |
Mechanisms for the inhibition of genital vascular responses by antidepressants in a female rabbit model.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Arginine; Blood Vessels; Citalopram; Cyclohexanols; Drug Interactions; Duloxetine Hydrochloride; Female; Nitric Oxide; Norepinephrine; Paroxetine; Phentolamine; Rabbits; Regional Blood Flow; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Vagina; Vasodilation; Venlafaxine Hydrochloride | 2004 |
New developments in the management of stress urinary incontinence.
Topics: Adrenergic Uptake Inhibitors; Age Distribution; Duloxetine Hydrochloride; Female; Humans; Prevalence; Risk Factors; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2004 |
[Duloxetine and other tricyclic antidepressive agents: pharmacodynamic effects in the lower urinary tract].
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents, Tricyclic; Duloxetine Hydrochloride; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urethra; Urinary Bladder | 2004 |
Stress incontinence: help at hand.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Drug Industry; Duloxetine Hydrochloride; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2004 |
Synthesis and biological activity of some known and putative duloxetine metabolites.
Topics: Adrenergic Uptake Inhibitors; Binding Sites; Cloning, Molecular; Dopamine Plasma Membrane Transport Proteins; Duloxetine Hydrochloride; Glucuronides; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Models, Chemical; Nerve Tissue Proteins; Radioligand Assay; Sulfates; Thiophenes | 2004 |
Central nervous system control of the lower urinary tract: new pharmacological approaches to stress urinary incontinence in women.
Topics: Central Nervous System; Duloxetine Hydrochloride; Female; Humans; Muscle, Smooth; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Reflex; Selective Serotonin Reuptake Inhibitors; Spinal Cord; Sympathetic Nervous System; Thiophenes; Urethra; Urinary Bladder; Urinary Incontinence, Stress; Urination; Urodynamics | 2004 |
Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats.
Topics: Acute Disease; Amines; Amitriptyline; Animals; Conscious Sedation; Cyclohexanecarboxylic Acids; Cyclohexanols; Cyclopropanes; Disease Models, Animal; Drug Therapy, Combination; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Methyltyrosines; Milnacipran; Neuromuscular Junction; Norepinephrine; p-Chloroamphetamine; Pain; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Thiophenes; Venlafaxine Hydrochloride | 2004 |
Duloxetine's role in the treatment of depression and associated painful physical symptoms.
Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Pain; Pain Measurement; Thiophenes; Treatment Outcome | 2004 |
New approaches in the pharmacological treatment of stress urinary incontinence.
Topics: Duloxetine Hydrochloride; Female; Humans; Prevalence; Quality of Life; Risk Factors; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress; Urogenital Surgical Procedures | 2004 |
[Physical recovery is part of remission].
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Nursing Assessment; Personality Inventory; Selective Serotonin Reuptake Inhibitors; Somatoform Disorders; Thiophenes; Treatment Outcome | 2004 |
[Successful phase III study with serotonin-noradrenaline reuptake inhibitor. Soon a drug to control stress incontinence].
Topics: Adrenergic Uptake Inhibitors; Clinical Trials, Phase III as Topic; Duloxetine Hydrochloride; Female; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2004 |
The efficacy of duloxetine: a comprehensive summary of results from MMRM and LOCF_ANCOVA in eight clinical trials.
Topics: Analysis of Variance; Antidepressive Agents; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Data Interpretation, Statistical; Depressive Disorder, Major; Drug Approval; Duloxetine Hydrochloride; Endpoint Determination; Humans; Longitudinal Studies; Models, Statistical; Pain Measurement; Placebos; Psychiatric Status Rating Scales; Thiophenes; Treatment Outcome | 2004 |
New drugs and dosage forms.
Topics: Clobetasol; Clozapine; Detergents; Dosage Forms; Drug Prescriptions; Duloxetine Hydrochloride; Humans; Injections; Secretin; Technetium; Thiophenes | 2004 |
Duloxetine (Cymbalta): a new SNRI for depression.
Topics: Administration, Oral; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Depression; Drug Interactions; Duloxetine Hydrochloride; Half-Life; Humans; Liver; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2004 |
Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents.
Topics: Adrenergic Uptake Inhibitors; Amines; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Ibuprofen; Inflammation; Male; Mice; Morphine; Norepinephrine; Pain; Pain Measurement; Postural Balance; Rats; Rats, Sprague-Dawley; Reaction Time; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2005 |
[FDA approval for the antidepressive drug Cymbalta].
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depressive Disorder; Drug Approval; Duloxetine Hydrochloride; Germany; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; United States | 2004 |
[The 10-minute consultation. Urinary incontinence in a woman].
Topics: Adrenergic Uptake Inhibitors; Cholinergic Antagonists; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Obesity; Postmenopause; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence; Urinary Incontinence, Stress; Urodynamics | 2004 |
The brain leads the way.
Topics: Benzylamines; Drug Industry; Duloxetine Hydrochloride; Ejaculation; Forecasting; Humans; Naphthalenes; Selective Serotonin Reuptake Inhibitors; Sexual Dysfunction, Physiological; Thiophenes; Urinary Incontinence, Stress; Wit and Humor as Topic | 2004 |
Does the new antidepressant duloxetine (Cymbalta) have any advantages over other antidepressant drugs?
Topics: Antidepressive Agents; Duloxetine Hydrochloride; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2004 |
Duloxetine hydrochloride.
Topics: Animals; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Marketing; Molecular Structure; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2004 |
Molecule of the month. Duloxetine hydrochloride.
Topics: Adult; Diabetic Neuropathies; Drug Administration Schedule; Duloxetine Hydrochloride; Fibromyalgia; Humans; Multicenter Studies as Topic; Thiophenes; Time Factors | 2004 |
Biotransformations for the production of the chiral drug (S)-Duloxetine catalyzed by a novel isolate of Candida tropicalis.
Topics: Biodegradation, Environmental; Candida tropicalis; Cellulose; Duloxetine Hydrochloride; Hydrogen-Ion Concentration; Propylamines; Soil Microbiology; Temperature; Thiophenes | 2005 |
[Stress incontinence in general practice].
Topics: Adrenergic Uptake Inhibitors; Duloxetine Hydrochloride; Exercise; Humans; Pelvic Floor; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress; Urodynamics | 2004 |
[Duloxetine reduces pain and depression].
Topics: Adrenergic Uptake Inhibitors; Analgesics; Antidepressive Agents; Depressive Disorder; Drug Approval; Duloxetine Hydrochloride; Germany; Humans; Pain; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2004 |
[Duloxetine receives positive recommendation by the Scientific Committee of EMEA for treatment of depression].
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depressive Disorder, Major; Diabetic Neuropathies; Drug Approval; Duloxetine Hydrochloride; Europe; Humans; Pharmacy and Therapeutics Committee; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2004 |
Antinociceptive effects of the antidepressants amitriptyline, duloxetine, mirtazapine and citalopram in animal models of acute, persistent and neuropathic pain.
Topics: Acute Disease; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Chronic Disease; Citalopram; Disease Models, Animal; Duloxetine Hydrochloride; Male; Mianserin; Mirtazapine; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Thiophenes | 2005 |
Some antipsychotics' effect on suicide; duloxetine's promise for elderly.
Topics: Aged; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Duloxetine Hydrochloride; Folic Acid; Humans; Suicide Prevention; Thiophenes; United States | 2004 |
Duloxetine for the treatment of major depressive disorder in older patients.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2005 |
Neonatal brain injury.
Topics: Diagnosis, Differential; Duloxetine Hydrochloride; Female; Fetus; Humans; Infant, Newborn; Pregnancy; Prenatal Exposure Delayed Effects; Seizures; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2005 |
Duloxetine fights major depressive disorder.
Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Thiophenes | 2005 |
[Stress incontinence. How does the bladder become leakproof again?].
Topics: Biofeedback, Psychology; Combined Modality Therapy; Duloxetine Hydrochloride; Electric Stimulation Therapy; Female; Humans; Physical Therapy Modalities; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress; Urodynamics | 2005 |
Urinary incontinence: a diverse condition.
Topics: Duloxetine Hydrochloride; Electric Stimulation Therapy; Electromagnetic Phenomena; Female; Humans; Magnetics; Male; Thiophenes; Urinary Incontinence | 2005 |
Mixed incontinence.
Topics: Adrenergic Uptake Inhibitors; Benzhydryl Compounds; Controlled Clinical Trials as Topic; Cresols; Duloxetine Hydrochloride; Female; Humans; Multicenter Studies as Topic; Muscarinic Antagonists; Phenylpropanolamine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Tolterodine Tartrate; Treatment Outcome; Urinary Incontinence; Urinary Incontinence, Stress; Urodynamics | 2005 |
[Change in the point of view].
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depressive Disorder; Duloxetine Hydrochloride; Humans; Norepinephrine; Nursing Diagnosis; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2005 |
Cost-effectiveness inferences from bootstrap quadrant confidence levels: three degrees of dominance.
Topics: Adult; Antidepressive Agents; Confidence Intervals; Cost-Benefit Analysis; Depressive Disorder; Drug Costs; Drug Therapy; Duloxetine Hydrochloride; Female; Humans; Male; Models, Statistical; Pharmaceutical Preparations; Randomized Controlled Trials as Topic; Research Design; Thiophenes | 2005 |
[Management of psychological symptoms and physical symptoms of depression. Rapid re-integration of patients into employment].
Topics: Antidepressive Agents; Depressive Disorder; Duloxetine Hydrochloride; Humans; Rehabilitation, Vocational; Secondary Prevention; Somatoform Disorders; Thiophenes; Treatment Outcome | 2005 |
[Dual mechanism of action. Remission of physical symptoms].
Topics: Antidepressive Agents; Back Pain; Clinical Trials as Topic; Depressive Disorder; Duloxetine Hydrochloride; Humans; Somatoform Disorders; Thiophenes | 2005 |
alpha(2)-Adrenoceptor involvement in the in vitro inhibitory effect of citalopram on a subpopulation of rat locus coeruleus neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amphetamines; Animals; Bridged Bicyclo Compounds, Heterocyclic; Brimonidine Tartrate; Citalopram; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Idazoxan; In Vitro Techniques; Locus Coeruleus; Male; Methiothepin; Naloxone; Narcotic Antagonists; Neurons; Norepinephrine; Oxazines; Piperazines; Piperidines; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes | 2005 |
FDA warns that antidepressants may increase suicidality in adults.
Topics: Adult; Antidepressive Agents; Duloxetine Hydrochloride; Female; Humans; Suicide; Thiophenes; United States; United States Food and Drug Administration; Urinary Incontinence, Stress | 2005 |
Chronic treatment with duloxetine is necessary for an anxiolytic-like response in the mouse zero maze: the role of the serotonin transporter.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Anxiety Agents; Antidepressive Agents; Arousal; Brain; Carrier Proteins; Cerebral Cortex; Duloxetine Hydrochloride; Female; Hippocampus; Maze Learning; Mice; Norepinephrine; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Thiophenes | 2005 |
Overactive bladder.
Topics: Benzilates; Duloxetine Hydrochloride; Humans; Nortropanes; Parasympatholytics; Primary Health Care; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence; Urinary Incontinence, Stress | 2005 |
Duloxetine associated with smoking cessation.
Topics: Adult; Depression; Duloxetine Hydrochloride; Humans; Male; Selective Serotonin Reuptake Inhibitors; Smoking Cessation; Thiophenes | 2005 |
Post-mortem human brain autoradiography of the norepinephrine transporter using (S,S)-[18F]FMeNER-D2.
Topics: Adrenergic Uptake Inhibitors; Autopsy; Autoradiography; Brain; Desipramine; Duloxetine Hydrochloride; Fluorine Radioisotopes; Humans; Morpholines; Postmortem Changes; Radioligand Assay; Thiophenes | 2005 |
[A challenge].
Topics: Adrenergic Uptake Inhibitors; Duloxetine Hydrochloride; Empathy; Female; Humans; Nurse-Patient Relations; Quality of Life; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2005 |
Duloexetine (Cymbalta) for treatment of major depressive disorder.
Topics: Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2005 |
Detective work: reading fine print, insurers question studies of drugs; Kaiser's veteran sleuth scours medical-journal articles and sees marketing spin; doctors fear loss of choices.
Topics: Antidepressive Agents; Biomedical Research; California; Clinical Trials as Topic; Cost Control; Cyclohexanols; Deception; Drug Costs; Drug Industry; Duloxetine Hydrochloride; Formularies as Topic; Health Maintenance Organizations; Humans; Insurance, Pharmaceutical Services; Marketing of Health Services; Publishing; Research Design; Thiophenes; United States; Venlafaxine Hydrochloride | 2005 |
An open-label study of duloxetine for the treatment of major depressive disorder: comparison of switching versus initiating treatment approaches.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Citalopram; Cyclohexanols; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Fluvoxamine; Humans; Male; Middle Aged; Paroxetine; Sertraline; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2005 |
Duloxetine in the treatment of panic disorder.
Topics: Adult; Antidepressive Agents; Duloxetine Hydrochloride; Female; Humans; Panic Disorder; Thiophenes | 2006 |
Moving beyond balance for a better antidepressant.
Topics: Antidepressive Agents; Cyclohexanols; Depressive Disorder; Duloxetine Hydrochloride; Humans; Neurotransmitter Uptake Inhibitors; Thiophenes; Venlafaxine Hydrochloride | 2005 |
[Duloxetine. A new preparation for patients with urinary incontinence].
Topics: Adrenergic Uptake Inhibitors; Animals; Duloxetine Hydrochloride; Female; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Bladder; Urinary Incontinence, Stress | 2005 |
[Brief case report. Duloxetine in Cotard syndrome].
Topics: Affective Disorders, Psychotic; Aged; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Citalopram; Delusions; Depersonalization; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Long-Term Care; Olanzapine; Risperidone; Syndrome; Thiophenes | 2005 |
Sample size estimation for the van Elteren test--a stratified Wilcoxon-Mann-Whitney test.
Topics: Clinical Trials as Topic; Computer Simulation; Duloxetine Hydrochloride; Female; Humans; Research Design; Sample Size; Statistics, Nonparametric; Thiophenes; Urinary Incontinence, Stress | 2006 |
Successful treatment with duloxetine in a case of treatment refractory bulimia nervosa: a case report.
Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Bulimia; Drug Resistance; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2006 |
Duloxetine treatment for women awaiting continence surgery.
Topics: Combined Modality Therapy; Duloxetine Hydrochloride; Female; Humans; Prostheses and Implants; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress; Uterine Prolapse; Waiting Lists | 2006 |
Facilitatory neuromodulative effect of duloxetine on pudendal motor neurons controlling the urethral pressure: a functional urodynamic study in healthy women.
Topics: Blood Pressure; Duloxetine Hydrochloride; Female; Humans; Motor Neurons; Muscle Contraction; Pressure; Reference Values; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urethra | 2006 |
Medical management of depression.
Topics: Chemical and Drug Induced Liver Injury; Depressive Disorder; Duloxetine Hydrochloride; Humans; Liver Function Tests; Piperazines; Selective Serotonin Reuptake Inhibitors; Thiophenes; Triazoles | 2006 |
Preliminary results on the off-label use of duloxetine for the treatment of stress incontinence after radical prostatectomy or cystectomy.
Topics: Aged; Cystectomy; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Prostatectomy; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2006 |
[Duloxetine (Yentreve) in the general practice test: recommendation by the experts. Effective and tolerable therapy of symptoms in female stress incontinence].
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Clinical Trials as Topic; Duloxetine Hydrochloride; Female; Germany; Humans; Middle Aged; Practice Guidelines as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2005 |
The combination of duloxetine and bupropion for treatment-resistant major depressive disorder.
Topics: Adult; Antidepressive Agents; Bupropion; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Retrospective Studies; Thiophenes; Treatment Outcome | 2006 |
Duloxetine in the context of current needs and issues in treatment of women with stress urinary incontinence.
Topics: Adrenergic Uptake Inhibitors; Duloxetine Hydrochloride; Female; Humans; Needs Assessment; Thiophenes; Urinary Incontinence, Stress | 2006 |
Duloxetine-induced syndrome of inappropriate antidiuretic hormone secretion and seizures.
Topics: Antidepressive Agents; Depression; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Inappropriate ADH Syndrome; Medical Errors; Middle Aged; Seizures; Thiophenes; Treatment Outcome | 2006 |
Acute and long-term administration of citalopram desensitizes alpha2-adrenoceptors in the rat vas deferens.
Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Brimonidine Tartrate; Citalopram; Dose-Response Relationship, Drug; Drug Administration Schedule; Duloxetine Hydrochloride; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Vas Deferens | 2006 |
Synergistic interactions between the dual serotonergic, noradrenergic reuptake inhibitor duloxetine and the non-steroidal anti-inflammatory drug ibuprofen in inflammatory pain in rodents.
Topics: Acetic Acid; Adrenergic Uptake Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Carrageenan; Drug Synergism; Duloxetine Hydrochloride; Hyperalgesia; Ibuprofen; Inflammation; Male; Mice; Mice, Inbred Strains; Norepinephrine; Pain; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes | 2007 |
Interaction of duloxetine and warfarin causing severe elevation of international normalized ratio.
Topics: Adult; Anticoagulants; Antidepressive Agents; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; International Normalized Ratio; Thiophenes; Warfarin | 2006 |
Exacerbation of PTSD symptoms with use of duloxetine.
Topics: Acute Disease; Combat Disorders; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Neurotransmitter Uptake Inhibitors; Stress Disorders, Post-Traumatic; Thiophenes | 2006 |
Effect of chronic administration of duloxetine on serotonin and norepinephrine transporter binding sites in rat brain.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Autoradiography; Brain; Chromatography, High Pressure Liquid; Desipramine; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Male; Norepinephrine Plasma Membrane Transport Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Thiophenes | 2007 |
Biological perspectives. Serotonin and norepinephrine reuptake inhibitors (SNRIs): venlafaxine and duloxetine.
Topics: Adrenergic Uptake Inhibitors; Adult; Cyclohexanols; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Venlafaxine Hydrochloride | 2006 |
Planning and analysis of three-arm non-inferiority trials with binary endpoints.
Topics: Controlled Clinical Trials as Topic; Data Interpretation, Statistical; Depression; Duloxetine Hydrochloride; Humans; Paroxetine; Research Design; Sample Size; Selective Serotonin Reuptake Inhibitors; Statistics as Topic; Therapeutic Equivalency; Thiophenes | 2007 |
Duloxetine treatment of major depressive episodes in the course of psychotic disorders.
Topics: Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Personality Inventory; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology; Thiophenes; Treatment Outcome | 2006 |
Duloxetine for childhood depression with pain and dissociative symptoms.
Topics: Antidepressive Agents; Benzodiazepines; Child; Depressive Disorder, Major; Dissociative Disorders; Duloxetine Hydrochloride; Female; Humans; Olanzapine; Pain; Thiophenes | 2006 |
N-(1,2-diphenylethyl)piperazines: a new class of dual serotonin/noradrenaline reuptake inhibitor.
Topics: Amines; Chemistry, Pharmaceutical; Drug Design; Duloxetine Hydrochloride; Humans; Models, Chemical; Norepinephrine; Piperazines; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Thiophenes | 2006 |
Duloxetine treatment of stress urinary incontinence in women: effects of demographics, obesity, chronic lung disease, hypoestrogenism, diabetes mellitus, and depression on efficacy.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Comorbidity; Controlled Clinical Trials as Topic; Demography; Depression; Diabetes Mellitus; Duloxetine Hydrochloride; Estrogens; Female; Humans; Lung Diseases; Middle Aged; Obesity; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2007 |
Case report: fulminant hepatic failure involving duloxetine hydrochloride.
Topics: Antidepressive Agents; Duloxetine Hydrochloride; Fatal Outcome; Female; Humans; Liver Failure, Acute; Middle Aged; Thiophenes | 2006 |
Combined use of ECT with duloxetine and olanzapine: a case report.
Topics: Adult; Benzodiazepines; Combined Modality Therapy; Depressive Disorder, Major; Duloxetine Hydrochloride; Electroconvulsive Therapy; Female; Humans; Olanzapine; Selective Serotonin Reuptake Inhibitors; Stress Disorders, Post-Traumatic; Thiophenes | 2006 |
Is HCl duloxetine effective in the management of urinary stress incontinence after radical prostatectomy?
Topics: Duloxetine Hydrochloride; Humans; Male; Middle Aged; Prostatectomy; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress; Urodynamics | 2006 |
[Physical complaints can overlap mental symptoms. Diffuse pain? Think about depression!].
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depression; Diagnosis, Differential; Duloxetine Hydrochloride; Female; Humans; Male; Pain; Recurrence; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors | 2006 |
[Duloxetin effective in depression and pain: high remission rates obtained].
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Clinical Trials as Topic; Depression; Dopamine Uptake Inhibitors; Duloxetine Hydrochloride; Humans; Pain; Pain Measurement; Placebos; Psychiatric Status Rating Scales; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors | 2006 |
Determination of drug binding to plasma proteins using competitive equilibrium binding to dextran-coated charcoal.
Topics: Adsorption; Algorithms; Binding, Competitive; Blood Proteins; Carboxylic Acids; Charcoal; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Dextrans; Duloxetine Hydrochloride; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Nitriles; Pharmaceutical Preparations; Phosphodiesterase Inhibitors; Protein Binding; Selective Serotonin Reuptake Inhibitors; Thiophenes; Ultrafiltration | 2006 |
Does duloxetine safely and effectively reduce the severity of diabetic peripheral neuropathic pain?
Topics: Antidepressive Agents; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Humans; Multicenter Studies as Topic; Pain; Pain Measurement; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2006 |
The use of duloxetine for stress incontinence after prostatectomy.
Topics: Duloxetine Hydrochloride; Humans; Male; Prostatectomy; Prostatic Diseases; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2006 |
Analgesic effects of serotonergic, noradrenergic or dual reuptake inhibitors in the carrageenan test in rats: evidence for synergism between serotonergic and noradrenergic reuptake inhibition.
Topics: Adrenergic Uptake Inhibitors; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Chemistry; Carrageenan; Cyclohexanols; Desipramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Duloxetine Hydrochloride; Edema; Fluoxetine; Hot Temperature; Hyperalgesia; Male; Norepinephrine; Paroxetine; Pressure; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline; Thiophenes; Venlafaxine Hydrochloride | 2006 |
The effects of duloxetine on urethral function and sphincter morphology.
Topics: Adult; Aged; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes; Ultrasonography; Urethra; Urinary Incontinence, Stress | 2007 |
Cost-effectiveness of duloxetine versus routine treatment for U.S. patients with diabetic peripheral neuropathic pain.
Topics: Antidepressive Agents; Cost-Benefit Analysis; Diabetic Neuropathies; Drug Costs; Duloxetine Hydrochloride; Humans; Pain; Thiophenes | 2006 |
A case of hyponatremia induced by duloxetine.
Topics: Adrenergic Uptake Inhibitors; Aged; Duloxetine Hydrochloride; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2006 |
Serotonin syndrome precipitated by linezolid in a medically ill patient on duloxetine.
Topics: Acetamides; Anti-Infective Agents; Antidepressive Agents; Depression; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Linezolid; Middle Aged; Monoamine Oxidase Inhibitors; Oxazolidinones; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Surgical Wound Dehiscence; Thiophenes | 2006 |
Serotonin syndrome from the interaction of cyclobenzaprine with other serotoninergic drugs.
Topics: Aged; Amitriptyline; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Phenelzine; Serotonin Syndrome; Thiophenes | 2006 |
Dyskinesia during treatment with duloxetine.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Clozapine; Duloxetine Hydrochloride; Dyskinesia, Drug-Induced; Female; Humans; Psychiatric Status Rating Scales; Schizophrenia, Paranoid; Thiophenes | 2006 |
Prescribing update: why choose duloxetine for depression?
Topics: Antidepressive Agents; Choice Behavior; Depressive Disorder; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Drug Prescriptions; Duloxetine Hydrochloride; Humans; Nurse's Role; Nursing Assessment; Patient Selection; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2007 |
A first look at duloxetine (Cymbalta) in a postmortem laboratory.
Topics: Adult; Antidepressive Agents; Duloxetine Hydrochloride; Fatal Outcome; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Thiophenes | 2006 |
Power approximation for the van Elteren test based on location-scale family of distributions.
Topics: Algorithms; Analysis of Variance; Antidepressive Agents; Clinical Trials as Topic; Combined Modality Therapy; Computer Simulation; Data Interpretation, Statistical; Duloxetine Hydrochloride; Female; Humans; Randomized Controlled Trials as Topic; Reference Values; Sample Size; Thiophenes; Urinary Incontinence, Stress | 2006 |
Comparative effects of clomipramine and duloxetine on detrusor and striated sphincter function in male and female rabbits.
Topics: Animals; Clomipramine; Duloxetine Hydrochloride; Female; Male; Muscle, Smooth; Rabbits; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Bladder | 2006 |
Isolation and characterisation of a phenolic impurity in a commercial sample of duloxetine.
Topics: Drug Contamination; Duloxetine Hydrochloride; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Phenol; Selective Serotonin Reuptake Inhibitors; Spectrometry, Mass, Electrospray Ionization; Thiophenes | 2007 |
Does treatment with duloxetine for neuropathic pain impact glycemic control?
Topics: Adult; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Glycated Hemoglobin; Humans; Lipids; Male; Middle Aged; Neuritis; Placebos; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2007 |
Immediate switching from moclobemide to duloxetine may induce serotonin syndrome.
Topics: Antidepressive Agents; Depressive Disorder, Major; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Thiophenes | 2006 |
Duloxetine and hyponatremia: a report of 5 cases.
Topics: Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Hyponatremia; Male; Middle Aged; Thiophenes | 2007 |
Duloxetine-induced excessive disturbing and disabling yawning.
Topics: Adult; Anxiety Disorders; Depressive Disorder; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes; Yawning | 2007 |
Duloxetine-induced ultrarapid cycling in an adolescent with bipolar depression.
Topics: Adolescent; Antidepressive Agents; Bipolar Disorder; Duloxetine Hydrochloride; Euphoria; Female; Humans; Periodicity; Thiophenes | 2007 |
A retrospective pooled analysis of duloxetine safety in 23,983 subjects.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anxiety Disorders; Depressive Disorder, Major; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Prevalence; Retrospective Studies; Thiophenes; United States; Urinary Incontinence, Stress | 2007 |
Determination of duloxetine in human plasma via LC/MS and subsequent application to a pharmacokinetic study in healthy Chinese volunteers.
Topics: Administration, Oral; Adrenergic Uptake Inhibitors; Adult; China; Chromatography, Liquid; Duloxetine Hydrochloride; Female; Humans; Male; Mass Spectrometry; Thiophenes; Volunteers | 2007 |
Facial flushing associated with duloxetine use.
Topics: Adult; Botulinum Toxins, Type A; Capsules; Duloxetine Hydrochloride; Female; Flushing; Humans; Migraine Disorders; Pindolol; Selective Serotonin Reuptake Inhibitors; Sleep Initiation and Maintenance Disorders; Thiophenes | 2007 |
Chronic duloxetine treatment induces specific changes in the expression of BDNF transcripts and in the subcellular localization of the neurotrophin protein.
Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Drug Administration Schedule; Duloxetine Hydrochloride; Electrophoretic Mobility Shift Assay; Exons; Gene Expression Regulation; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Subcellular Fractions; Thiophenes; Time Factors | 2007 |
Duloxetine treatment of pediatric chronic pain and co-morbid major depressive disorder.
Topics: Abdominal Pain; Adolescent; Antidepressive Agents; Chronic Disease; Comorbidity; Crohn Disease; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Low Back Pain; Pain; Sick Role; Thiophenes | 2007 |
Development and validation of a liquid chromatography-tandem mass spectrometric method for the determination of the major metabolites of duloxetine in human plasma.
Topics: Antidepressive Agents; Chromatography, Liquid; Duloxetine Hydrochloride; Humans; Tandem Mass Spectrometry; Thiophenes | 2007 |
Tolerability and efficacy of duloxetine in a nontrial situation.
Topics: Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Patient Satisfaction; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Bladder, Overactive; Urinary Incontinence, Stress; Withholding Treatment | 2007 |
Eosinophilic pneumonia due to duloxetine.
Topics: Adult; Antidepressive Agents; Biopsy; Bronchoscopy; Cryptogenic Organizing Pneumonia; Diagnosis, Differential; Duloxetine Hydrochloride; Humans; Lung; Male; Pulmonary Eosinophilia; Thiophenes; Tomography, X-Ray Computed | 2007 |
Pregabalin and duloxetine for the treatment of neuropathic pain disorders.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain; Pregabalin; Randomized Controlled Trials as Topic; Thiophenes | 2007 |
[Evaluation of women's preferences for the treatment of stress urinary incontinence using the paired comparisons method].
Topics: Adrenergic Uptake Inhibitors; Age Factors; Cross-Sectional Studies; Duloxetine Hydrochloride; Exercise Therapy; Female; Humans; Matched-Pair Analysis; Menopause; Middle Aged; Patient Satisfaction; Patients; Pelvic Floor; Reproductive History; Severity of Illness Index; Surveys and Questionnaires; Thiophenes; Urinary Incontinence, Stress; Urologic Surgical Procedures; Women | 2007 |
Successful treatment of refractory hypochondriasis with duloxetine.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Antidepressive Agents, Second-Generation; Duloxetine Hydrochloride; Female; Humans; Hypochondriasis; Middle Aged; Paroxetine; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2007 |
Duloxetine in the treatment of social anxiety disorder.
Topics: Adrenergic Uptake Inhibitors; Adult; Anxiety Disorders; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2007 |
Recurrent hyponatremia after substitution of citalopram with duloxetine.
Topics: Aged, 80 and over; Antidepressive Agents, Tricyclic; Citalopram; Depression; Duloxetine Hydrochloride; Female; Humans; Hyponatremia; Nortriptyline; Recurrence; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2007 |
Simple options for improving signal detection in antidepressant clinical trials.
Topics: Antidepressive Agents; Citalopram; Clinical Trials as Topic; Databases, Factual; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Fluoxetine; Likelihood Functions; Models, Statistical; Paroxetine; Personality Inventory; Placebo Effect; Psychometrics; Reproducibility of Results; Research Design; Signal Detection, Psychological; Thiophenes; Treatment Outcome | 2007 |
Cymbalta and your blood glucose.
Topics: Antidepressive Agents; Blood Glucose; Diabetic Nephropathies; Duloxetine Hydrochloride; Humans; Thiophenes | 2007 |
HPLC analysis of the novel antidepressant duloxetine in human plasma after an original solid-phase extraction procedure.
Topics: Antidepressive Agents; Calibration; Chromatography, High Pressure Liquid; Depression; Duloxetine Hydrochloride; Humans; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Thiophenes | 2007 |
Pharmacological validation of a model of cystitis pain in the mouse.
Topics: Analgesics; Animals; Behavior, Animal; Cyclophosphamide; Cystitis; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Ketorolac; Male; Mice; Morphine; Pain; Pain Measurement; Thiophenes | 2007 |
Hyperprolactinemia and galactorrhea induced by serotonin and norepinephrine reuptake inhibiting antidepressants.
Topics: Adrenergic Uptake Inhibitors; Adult; Cyclohexanols; Duloxetine Hydrochloride; Dysthymic Disorder; Female; Galactorrhea; Humans; Hyperprolactinemia; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Venlafaxine Hydrochloride | 2007 |
Manic switching in patients receiving duloxetine.
Topics: Adrenergic Uptake Inhibitors; Adult; Bipolar Disorder; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychotic Disorders; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes | 2007 |
Involvement of reflex urethral closure mechanisms in urethral resistance under momentary stress condition induced by electrical stimulation of rat abdomen.
Topics: Abdomen; Adrenergic Uptake Inhibitors; Animals; Duloxetine Hydrochloride; Electric Stimulation; Female; Rats; Rats, Sprague-Dawley; Reflex; Stress, Physiological; Thiophenes; Urethra | 2007 |
Duloxetine--three birds with one stone?
Topics: Antidepressive Agents; Depressive Disorder, Major; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2007 |
Career lifetime advances and key developments: diabetes.
Topics: Amines; Amitriptyline; Analgesics; Antidepressive Agents; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Thiophenes | 2007 |
Detrusor overactivity successfully treated with duloxetine.
Topics: Adrenergic Uptake Inhibitors; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Thiophenes; Urinary Bladder, Overactive | 2007 |
Premature ejaculation: definition and drug treatment.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Antidepressive Agents, Tricyclic; Duloxetine Hydrochloride; Ejaculation; Humans; Male; Selective Serotonin Reuptake Inhibitors; Sexual Dysfunction, Physiological; Thiophenes | 2007 |
A validated UV spectrophotometric method for determination of duloxetine hydrochloride.
Topics: Analysis of Variance; Antidepressive Agents; Capsules; Chemistry, Pharmaceutical; Duloxetine Hydrochloride; Reference Standards; Reproducibility of Results; Spectrophotometry; Thiophenes | 2007 |
Duloxetine status.
Topics: Antidepressive Agents; Clinical Trials as Topic; Duloxetine Hydrochloride; Fibromyalgia; Humans; Pain; Thiophenes | 2007 |
Dopamine D(1) and D(2) receptor agonism enhances antinociception mediated by the serotonin and noradrenaline reuptake inhibitor duloxetine in the rat formalin test.
Topics: Analgesics; Animals; Antidepressive Agents; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Formaldehyde; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors | 2007 |
Successful duloxetine use to prevent venlafaxine withdrawal symptoms.
Topics: Adrenergic Uptake Inhibitors; Adult; Cyclohexanols; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Neurotransmitter Uptake Inhibitors; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome; Thiophenes; Venlafaxine Hydrochloride | 2008 |
Duloxetine treatment of Premenstrual Dysphoric Disorder: case reports.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Neurotransmitter Uptake Inhibitors; Premenstrual Syndrome; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2008 |
Duloxetine as a treatment for stress incontinence--where are we now?
Topics: Adrenergic Uptake Inhibitors; Drug Approval; Duloxetine Hydrochloride; Female; Humans; Male; Randomized Controlled Trials as Topic; Thiophenes; Urinary Incontinence, Stress | 2008 |
Determination of duloxetine in human plasma by liquid chromatography with atmospheric pressure ionization-tandem mass spectrometry and its application to pharmacokinetic study.
Topics: Chromatography, Liquid; Duloxetine Hydrochloride; Humans; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Tandem Mass Spectrometry; Thiophenes | 2007 |
Cost effectiveness of duloxetine in the treatment of diabetic peripheral neuropathic pain in the UK.
Topics: Amines; Amitriptyline; Antidepressive Agents; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Econometric; Paclitaxel; Pain Measurement; Prospective Studies; Quality-Adjusted Life Years; Sickness Impact Profile; Thiophenes; Treatment Outcome; United Kingdom | 2008 |
BDNF level in the rat prefrontal cortex increases following chronic but not acute treatment with duloxetine, a dual acting inhibitor of noradrenaline and serotonin re-uptake.
Topics: Animals; Body Weight; Brain-Derived Neurotrophic Factor; Duloxetine Hydrochloride; Male; Norepinephrine; Prefrontal Cortex; Protein Isoforms; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Time Factors | 2008 |
Effects of naltrexone, duloxetine, and a corticotropin-releasing factor type 1 receptor antagonist on binge-like alcohol drinking in rats.
Topics: Alcohol Deterrents; Animals; Behavior, Addictive; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Ethanol; Male; Naltrexone; Pyrimidines; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Saccharin; Self Administration; Sweetening Agents; Thiophenes | 2008 |
Potential drug-drug interaction between duloxetine and acenocoumarol in a patient with Alzheimer's disease.
Topics: Acenocoumarol; Alzheimer Disease; Anticoagulants; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; International Normalized Ratio; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2007 |
Suicidal ideation associated with duloxetine use: a case series.
Topics: Adult; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Risk Factors; Selective Serotonin Reuptake Inhibitors; Suicide; Thinking; Thiophenes | 2008 |
Successful treatment of nicotine withdrawal with duloxetine: a case report.
Topics: Adult; Alcohol Drinking; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Smoking; Substance Withdrawal Syndrome; Thiophenes; Tobacco Use Disorder | 2008 |
Duloxetine-induced cutaneous adverse reaction.
Topics: Adrenergic Uptake Inhibitors; Depressive Disorder, Major; Duloxetine Hydrochloride; Exanthema; Female; Humans; Middle Aged; Pruritus; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2008 |
Successful treatment of chronic fatigue syndrome with duloxetine and trijodthyronine--a case study.
Topics: Adult; Drug Therapy, Combination; Duloxetine Hydrochloride; Fatigue Syndrome, Chronic; Female; Humans; Thiophenes; Triiodothyronine | 2008 |
Combining mirtazapine and duloxetine in treatment-resistant depression improves outcomes and sexual function.
Topics: Adrenergic Uptake Inhibitors; Adult; Depressive Disorder, Major; Drug Resistance; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Histamine H1 Antagonists; Humans; Male; Mianserin; Mirtazapine; Selective Serotonin Reuptake Inhibitors; Sexual Dysfunctions, Psychological; Thiophenes; Treatment Outcome | 2008 |
Switching from serotonin reuptake inhibitors to duloxetine in patients with resistant obsessive compulsive disorder: a case series.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Dose-Response Relationship, Drug; Drug Resistance; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2008 |
Effective treatment of narcolepsy-cataplexy with duloxetine: a report of three cases.
Topics: Adult; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Narcolepsy; Selective Serotonin Reuptake Inhibitors; Thiophenes; Young Adult | 2009 |
The effect of duloxetine on urethral sphincter morphology.
Topics: Adult; Duloxetine Hydrochloride; Female; Humans; Pilot Projects; Selective Serotonin Reuptake Inhibitors; Thiophenes; Ultrasonography; Urethra; Urinary Incontinence, Stress | 2008 |
Response to duloxetine in a depressed, treatment-resistant adolescent female.
Topics: Adolescent; Antidepressive Agents; Combined Modality Therapy; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Phototherapy; Seasons; Thiophenes; Treatment Outcome | 2007 |
A Markov cost-utility analysis of escitalopram and duloxetine for the treatment of major depressive disorder.
Topics: Antidepressive Agents; Citalopram; Cost-Benefit Analysis; Depressive Disorder, Major; Drug Costs; Duloxetine Hydrochloride; Humans; Markov Chains; Models, Economic; Monte Carlo Method; Quality-Adjusted Life Years; Thiophenes; Treatment Outcome; United States | 2008 |
Human health risk assessments for three neuropharmaceutical compounds in surface waters.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Atomoxetine Hydrochloride; Benzodiazepines; Drug Residues; Duloxetine Hydrochloride; Environmental Exposure; Fishes; Food Analysis; Forecasting; Humans; Models, Statistical; No-Observed-Adverse-Effect Level; Olanzapine; Propylamines; Risk Assessment; Thiophenes; United States; Water Pollutants, Chemical; Water Supply | 2008 |
At-line quantitative ion mobility spectrometry for direct analysis of swabs for pharmaceutical manufacturing equipment cleaning verification.
Topics: Detergents; Drug Industry; Duloxetine Hydrochloride; Spectrum Analysis; Surface-Active Agents; Thiophenes | 2008 |
Glossopharyngeal neuralgia with cardiac syncope: an idiopathic case treated with carbamazepine and duloxetine.
Topics: Anticonvulsants; Antidepressive Agents; Carbamazepine; Duloxetine Hydrochloride; Glossopharyngeal Nerve Diseases; Humans; Male; Middle Aged; Syncope; Thiophenes | 2008 |
Study on fluorescence characteristics of duloxetine hydrochloride.
Topics: Antidepressive Agents; Ascorbic Acid; Cations; Duloxetine Hydrochloride; Hydrogen-Ion Concentration; Metals; Molecular Structure; Photochemical Processes; Solvents; Spectrometry, Fluorescence; Temperature; Thiophenes | 2008 |
[Efficacy of duloxetine in the treatment of chronic daily headache].
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Follow-Up Studies; Headache Disorders; Humans; Male; Middle Aged; Pain Measurement; Pain Threshold; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Treatment Outcome | 2007 |
[Treatment of chronic back pain with antidepressant cymbalta: an experimental study].
Topics: Adult; Antidepressive Agents; Chronic Disease; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Low Back Pain; Male; Middle Aged; Pain Measurement; Retrospective Studies; Severity of Illness Index; Thiophenes | 2007 |
Long-term trials of pregabalin and duloxetine for fibromyalgia symptoms: how study designs can affect placebo factors.
Topics: Adrenergic Uptake Inhibitors; Analgesics; Clinical Protocols; Clinical Trials as Topic; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Longitudinal Studies; Outcome Assessment, Health Care; Placebo Effect; Pregabalin; Thiophenes; Treatment Outcome | 2008 |
Heart failure worsening and exacerbation after venlafaxine and duloxetine therapy.
Topics: Adult; Aged; Cyclohexanols; Duloxetine Hydrochloride; Female; Heart Failure; Humans; Male; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Tachycardia; Thiophenes; Venlafaxine Hydrochloride; Ventricular Dysfunction, Left | 2008 |
Efficacy and tolerability of duloxetine in elderly patients with generalized anxiety disorder: a pooled analysis of four randomized, double-blind, placebo-controlled studies.
Topics: Adrenergic Uptake Inhibitors; Aged; Anxiety Disorders; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2008 |
Effect of duloxetine, a norepinephrine and serotonin reuptake inhibitor, on sneeze-induced urethral continence reflex in rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Duloxetine Hydrochloride; Female; Idazoxan; Methiothepin; Prazosin; Pressure; Rats; Rats, Sprague-Dawley; Reflex; Selective Serotonin Reuptake Inhibitors; Sneezing; Thiophenes; Urethra; Urinary Incontinence, Stress; Vagina | 2008 |
Duloxetine: an emerging evidence for fibromyalgia.
Topics: Analgesics; Antidepressive Agents; Cyclopropanes; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Milnacipran; Pregabalin; Randomized Controlled Trials as Topic; Thiophenes | 2009 |
Does pain mediate the pain interference with sleep problem in chronic pain? Findings from studies for management of diabetic peripheral neuropathic pain with duloxetine.
Topics: Antidepressive Agents; Chronic Disease; Comorbidity; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Incidence; Male; Middle Aged; Pain; Randomized Controlled Trials as Topic; Sleep Initiation and Maintenance Disorders; Thiophenes; Treatment Outcome; United States | 2008 |
Severe and symptomatic hyponatremia following duloxetine treatment.
Topics: Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Hyponatremia; Severity of Illness Index; Thiophenes | 2009 |
Duloxetine-induced hypomania: case report and brief review of the literature on SNRIs-induced mood switching.
Topics: Bipolar Disorder; Depressive Disorder; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2009 |
Non-fatal overdose of duloxetine in combination with other antidepressants and benzodiazepines.
Topics: Affect; Aged; Antidepressive Agents; Chromatography, High Pressure Liquid; Confusion; Depressive Disorder, Major; Drug Interactions; Drug Overdose; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Gastric Lavage; Humans; Life Change Events; Metabolic Clearance Rate; Suicide, Attempted; Thiophenes | 2009 |
Wine and drug evaluations: lessons on making comparisons of noninferiority.
Topics: Anxiety Disorders; Cross-Cultural Comparison; Cyclohexanols; Depressive Disorder; Drug Approval; Duloxetine Hydrochloride; Europe; Humans; Placebo Effect; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; United States; United States Food and Drug Administration; Venlafaxine Hydrochloride; Wine | 2008 |
Establishing non-inferiority in treatment trials in psychiatry: guidelines from an Expert Consensus Meeting.
Topics: Antidepressive Agents; Anxiety Disorders; Consensus Development Conferences as Topic; Cyclohexanols; Duloxetine Hydrochloride; Evidence-Based Medicine; Humans; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Venlafaxine Hydrochloride | 2008 |
A non-inferiority comparison of duloxetine and venlafaxine in the treatment of adult patients with generalized anxiety disorder.
Topics: Adult; Antidepressive Agents; Anxiety Disorders; Cyclohexanols; Data Interpretation, Statistical; Delayed-Action Preparations; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Venlafaxine Hydrochloride | 2008 |
Duloxetine (cymbalta) for fibromyalgia.
Topics: Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2008 |
A case of apical ballooning cardiomyopathy associated with duloxetine.
Topics: Adrenergic Uptake Inhibitors; Cardiomyopathies; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2008 |
Measurement of pain and medication effect in a study of duloxetine.
Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Pain; Pain Measurement; Prevalence; Severity of Illness Index; Thiophenes | 2008 |
Hepatic effects of duloxetine-III: analysis of hepatic events using external data sources.
Topics: Adrenergic Uptake Inhibitors; Adverse Drug Reaction Reporting Systems; Chemical and Drug Induced Liver Injury; Consumer Product Safety; Cyclohexanols; Databases as Topic; Duloxetine Hydrochloride; Humans; Liver; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Thiophenes; United States; United States Food and Drug Administration; Venlafaxine Hydrochloride | 2008 |
In vitro stability, potency, and dissolution of duloxetine enteric-coated pellets after exposure to applesauce, apple juice, and chocolate pudding.
Topics: Antidepressive Agents; Beverages; Drug Stability; Duloxetine Hydrochloride; Food; Food-Drug Interactions; Fruit; Tablets, Enteric-Coated; Thiophenes | 2008 |
Basal and stress-induced modulation of activity-regulated cytoskeletal associated protein (Arc) in the rat brain following duloxetine treatment.
Topics: Animals; Antidepressive Agents; Cytoskeletal Proteins; Duloxetine Hydrochloride; Entorhinal Cortex; Gene Expression; Male; Mesencephalon; Motor Cortex; Nerve Tissue Proteins; Physical Exertion; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Psychological; Swimming; Thiophenes; Time Factors; Up-Regulation | 2008 |
Duloxetine-associated tachycardia.
Topics: Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Duloxetine Hydrochloride; Dysthymic Disorder; Heart Rate; Humans; Male; Propranolol; Tachycardia; Thiophenes | 2008 |
Brain region-specific effects of short-term treatment with duloxetine, venlafaxine, milnacipran and sertraline on monoamine metabolism in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain; Cyclohexanols; Cyclopropanes; Dopamine; Duloxetine Hydrochloride; Homovanillic Acid; Male; Milnacipran; Norepinephrine; Organ Specificity; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline; Thiophenes; Time Factors; Venlafaxine Hydrochloride | 2009 |
The history and treatment of a bipolar patient diagnosed with Borna disease virus infection. Case report.
Topics: Adult; Amantadine; Antidepressive Agents; Bipolar Disorder; Borna Disease; Drug Administration Schedule; Drug Therapy, Combination; Duloxetine Hydrochloride; Humans; Male; Medical History Taking; Thiophenes; United States | 2008 |
Response to: Long-term trials of pregabalin and duloxetine for fibromyalgia symptoms: How study designs can affect placebo factors.
Topics: Adrenergic Uptake Inhibitors; Analgesics; Clinical Protocols; Clinical Trials as Topic; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Longitudinal Studies; Outcome Assessment, Health Care; Placebo Effect; Pregabalin; Thiophenes; Treatment Outcome | 2008 |
Duloxetine treatment of social anxiety disorder with comorbid major depression.
Topics: Adrenergic Uptake Inhibitors; Anxiety Disorders; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2008 |
Multiplicative interactions to enhance gabapentin to treat neuropathic pain.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Donepezil; Dose-Response Relationship, Drug; Drug Interactions; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Indans; Injections, Spinal; Ligation; Male; Neurotransmitter Uptake Inhibitors; Nootropic Agents; Pain; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Piperidines; Postural Balance; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Spinal Nerves; Thiophenes | 2008 |
[Evidence-based recommendations for the treatment of fibromyalgia syndrome].
Topics: Adrenergic Uptake Inhibitors; Analgesics; Antidepressive Agents; Combined Modality Therapy; Consensus Development Conferences as Topic; Cross-Sectional Studies; Duloxetine Hydrochloride; Evidence-Based Medicine; Exercise Therapy; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Practice Guidelines as Topic; Pregabalin; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2010 |
[Combination of dialectic and behavioral therapy (DBT) and duloxetin in kleptomania].
Topics: Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Combined Modality Therapy; Comorbidity; Depressive Disorder; Disruptive, Impulse Control, and Conduct Disorders; Duloxetine Hydrochloride; Follow-Up Studies; Humans; Male; Middle Aged; Patient Admission; Personality Disorders; Psychotherapy, Group; Thiophenes | 2009 |
[Dermatological side effects during therapy with serotonin noradrenaline reuptake inhibitors].
Topics: Drug Eruptions; Duloxetine Hydrochloride; Ecchymosis; Female; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Young Adult | 2008 |
Neurobehavioral and genotoxic parameters of duloxetine in mice using the inhibitory avoidance task and comet assay as experimental models.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Comet Assay; DNA Damage; Duloxetine Hydrochloride; Male; Memory; Mice; Thiophenes | 2009 |
Development and validation of chiral LC method for the enantiomeric separation of duloxetine on amylose based stationary phase.
Topics: Amylose; Chromatography, High Pressure Liquid; Drug Stability; Duloxetine Hydrochloride; Phenylcarbamates; Reproducibility of Results; Stereoisomerism; Thiophenes; Uncertainty | 2008 |
Successful duloxetine treatment of a binge eating disorder: a case report.
Topics: Adrenergic Uptake Inhibitors; Adult; Bulimia; Dose-Response Relationship, Drug; Drug Resistance; Duloxetine Hydrochloride; Eating; Humans; Male; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes | 2010 |
Antidepressant-induced sweating alleviated by aripiprazole.
Topics: Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Dopamine Agonists; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Hyperhidrosis; Middle Aged; Piperazines; Quinolones; Sweating; Thiophenes | 2008 |
A cost-utility comparison of four first-line medications in painful diabetic neuropathy.
Topics: Amines; Analgesics; Antidepressive Agents, Tricyclic; Cost-Benefit Analysis; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Desipramine; Diabetic Neuropathies; Duloxetine Hydrochloride; Economics, Pharmaceutical; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pregabalin; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Thiophenes | 2008 |
Acute stress responsiveness of the neurotrophin BDNF in the rat hippocampus is modulated by chronic treatment with the antidepressant duloxetine.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Corticosterone; Cytoplasm; Duloxetine Hydrochloride; Hippocampus; Male; Protein Isoforms; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Psychological; Synaptosomes; Thiophenes; Transcription, Genetic; Up-Regulation | 2009 |
Fibromyalgia coverage uneven despite recent drug approvals.
Topics: Analgesics; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Insurance, Pharmaceutical Services; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sickness Impact Profile; Thiophenes; United States; United States Food and Drug Administration | 2008 |
[Chronic pain and depression].
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Chronic Disease; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Pain; Prevalence; Thiophenes | 2008 |
Safety and efficacy of duloxetine in the treatment of diabetic peripheral neuropathic pain in older patients.
Topics: Age Factors; Aged; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2009 |
Serious suicide attempt with duloxetine treatment.
Topics: Depression; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Neck Pain; Selective Serotonin Reuptake Inhibitors; Suicide, Attempted; Thiophenes | 2008 |
A validated stability indicating rapid LC method for duloxetine HCl.
Topics: Calibration; Chromatography, High Pressure Liquid; Duloxetine Hydrochloride; Hot Temperature; Hydrolysis; Indicators and Reagents; Nootropic Agents; Oxidation-Reduction; Photolysis; Reference Standards; Reproducibility of Results; Solutions; Thiophenes | 2009 |
Open-label support for duloxetine for the treatment of panic disorder.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Panic Disorder; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2009 |
The facilitatory effect of duloxetine combined with pelvic floor muscle training on the excitability of urethral sphincter motor neurons.
Topics: Adult; Combined Modality Therapy; Duloxetine Hydrochloride; Exercise Therapy; Female; Humans; Motor Neurons; Muscle Contraction; Pelvic Floor; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urethra; Urinary Incontinence, Stress; Urodynamics; Young Adult | 2009 |
Determination of duloxetine in human plasma by capillary electrophoresis with laser-induced fluorescence detection.
Topics: Antidepressive Agents; Calibration; Capillary Electrochromatography; Chromatography, High Pressure Liquid; Duloxetine Hydrochloride; Humans; Reference Standards; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thiophenes | 2009 |
Serotonin-Norepinephrine Reuptake Inhibitor (SNRI) treatment for Isaacs syndrome with depression.
Topics: Adult; Depression; Duloxetine Hydrochloride; Humans; Isaacs Syndrome; Male; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2009 |
Cooperative opioid and serotonergic mechanisms generate superior antidepressant-like effects in a mice model of depression.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Behavior, Animal; Codeine; Depression; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Duloxetine Hydrochloride; Enzyme Inhibitors; Hindlimb Suspension; Male; Mice; Motor Activity; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Tramadol | 2009 |
Improvement with duloxetine in an adult ADHD patient.
Topics: Adrenergic Uptake Inhibitors; Adult; Attention Deficit Disorder with Hyperactivity; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2009 |
[Cymbalta (duloxetine) in the treatment of anxiety-depressive disorders in patients with discirculatory encephalopathy].
Topics: Adult; Aged; Antidepressive Agents; Anxiety Disorders; Brain Ischemia; Depressive Disorder; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychological Tests; Selective Serotonin Reuptake Inhibitors; Syndrome; Thiophenes; Treatment Outcome | 2009 |
Anti-nociceptive effect of duloxetine in mouse model of diabetic neuropathic pain.
Topics: Adenosine; Animals; Cerebral Cortex; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hot Temperature; Hyperalgesia; Male; Mice; Mice, Inbred Strains; Pain Measurement; Pain Threshold; Selective Serotonin Reuptake Inhibitors; Streptozocin; Thiophenes; Touch | 2009 |
Clinical outcome and tolerability of duloxetine in the treatment of major depressive disorder: a 12-week study with plasma levels.
Topics: Adrenergic Uptake Inhibitors; Aged; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome | 2010 |
Nontricyclic antidepressants for neuropathic pain #187.
Topics: Antidepressive Agents, Second-Generation; Bupropion; Cyclohexanols; Duloxetine Hydrochloride; Humans; Neuralgia; Selective Serotonin Reuptake Inhibitors; Thiophenes; Venlafaxine Hydrochloride | 2009 |
Antidepressant-associated myoclonic status in a patient with symptomatic generalized epilepsy: does risk occur with therapeutic doses?
Topics: Antidepressive Agents; Depression; Duloxetine Hydrochloride; Electroencephalography; Epilepsy, Generalized; Humans; Male; Middle Aged; Paroxetine; Seizures; Thiophenes | 2009 |
Serotonin syndrome induced by duloxetine.
Topics: Aged; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Thiophenes | 2009 |
Total residue analysis of swabs by ion mobility spectrometry.
Topics: Drug Industry; Duloxetine Hydrochloride; Excipients; Ions; Pharmaceutical Preparations; Sensitivity and Specificity; Spectrum Analysis; Thiophenes | 2009 |
[Therapy for urinary incontinence in general practice].
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Cholinergic Antagonists; Combined Modality Therapy; Data Collection; Duloxetine Hydrochloride; Education, Medical, Continuing; Family Practice; Female; Geriatrics; Germany; Humans; Incontinence Pads; Male; Medical History Taking; Middle Aged; Practice Patterns, Physicians'; Primary Health Care; Referral and Consultation; Thiophenes; Ultrasonography; Urinary Incontinence; Urology | 2009 |
Economic evaluation of duloxetine versus serotonin selective reuptake inhibitors and venlafaxine XR in treating major depressive disorder in Scotland.
Topics: Cost-Benefit Analysis; Cyclohexanols; Delayed-Action Preparations; Depressive Disorder; Duloxetine Hydrochloride; Health Care Costs; Humans; Mianserin; Mirtazapine; Prevalence; Quality of Life; Recurrence; Remission Induction; Scotland; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Venlafaxine Hydrochloride | 2010 |
[Treatment of female urinary incontinence].
Topics: Adrenergic Uptake Inhibitors; Botulinum Toxins, Type A; Cholinergic Antagonists; Cross-Sectional Studies; Duloxetine Hydrochloride; Female; Humans; Life Style; Risk Factors; Suburethral Slings; Thiophenes; Treatment Outcome; Urinary Incontinence | 2009 |
Successful pain relief of cutaneous leiomyomata due to reed syndrome with the combination treatment of pregabalin and duloxetine.
Topics: Adult; Analgesics, Non-Narcotic; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Leiomyoma; Pain; Pregabalin; Selective Serotonin Reuptake Inhibitors; Skin Neoplasms; Thiophenes | 2009 |
The short- and long-term effect of duloxetine on painful physical symptoms in patients with generalized anxiety disorder: results from three clinical trials.
Topics: Adult; Antidepressive Agents; Anxiety Disorders; Double-Blind Method; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pain; Pain Measurement; Randomized Controlled Trials as Topic; Secondary Prevention; Somatoform Disorders; Thiophenes; Treatment Outcome | 2009 |
Abnormal gait, due to inflammation but not nerve injury, reflects enhanced nociception in preclinical pain models.
Topics: Amines; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Axotomy; Carrageenan; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Edema; Freund's Adjuvant; Gabapentin; Gait; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Indomethacin; Inflammation; Male; Morphine; Neuralgia; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Thiophenes | 2009 |
Plasma levels and cerebrospinal fluid penetration by duloxetine in a patient with a non-fatal overdose during a suicide attempt.
Topics: Adult; Drug Overdose; Duloxetine Hydrochloride; Female; Humans; Suicide, Attempted; Thiophenes | 2009 |
The clinical importance of changes in the 0 to 10 numeric rating scale for worst, least, and average pain intensity: analyses of data from clinical trials of duloxetine in pain disorders.
Topics: Adrenergic Uptake Inhibitors; Aged; Disability Evaluation; Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Mathematics; Middle Aged; Outcome Assessment, Health Care; Pain Measurement; Randomized Controlled Trials as Topic; ROC Curve; Severity of Illness Index; Somatoform Disorders; Thiophenes; Treatment Outcome | 2010 |
Comparison of mechanical allodynia and the affective component of inflammatory pain in rats.
Topics: Analgesics, Non-Narcotic; Animals; Behavior, Animal; Celecoxib; Central Nervous System Agents; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Escape Reaction; Fluoxetine; Inflammation; Male; Motor Activity; Neuropsychological Tests; Pain; Pain Measurement; Physical Stimulation; Pyrazoles; Rats; Rats, Sprague-Dawley; Scopolamine; Sulfonamides; Thiophenes; Treatment Outcome | 2010 |
Duloxetine compliance and its association with healthcare costs among patients with diabetic peripheral neuropathic pain.
Topics: Aged; Aged, 80 and over; Cost-Benefit Analysis; Diabetic Nephropathies; Drug Costs; Duloxetine Hydrochloride; Female; Health Care Costs; Humans; Insurance Claim Review; Male; Medication Adherence; Middle Aged; Retrospective Studies; Thiophenes; United States | 2009 |
Duloxetine serum concentrations and clinical effects. Data from a therapeutic drug monitoring (TDM) survey.
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents; Chromatography, High Pressure Liquid; Depressive Disorder; Dose-Response Relationship, Drug; Drug Monitoring; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; ROC Curve; Severity of Illness Index; Spectrum Analysis; Thiophenes; Treatment Outcome; Ultraviolet Rays; Young Adult | 2009 |
Duloxetine and care management treatment of older adults with comorbid major depressive disorder and chronic low back pain: results of an open-label pilot study.
Topics: Aged; Anxiety; Chronic Disease; Comorbidity; Depressive Disorder, Major; Disability Evaluation; Disease Management; Duloxetine Hydrochloride; Female; Health Status; Humans; Low Back Pain; Male; Pain Measurement; Pilot Projects; Psychiatric Status Rating Scales; Quality of Life; Selective Serotonin Reuptake Inhibitors; Self Efficacy; Sleep; Surveys and Questionnaires; Thiophenes | 2010 |
Switching to duloxetine remits ziprasidone - associated urinary incontinence and improves neuropsychiatric behavior in dementia: possible relationship of incontinence to 5HT2 receptor blockade.
Topics: Aged, 80 and over; Alzheimer Disease; Dementia, Vascular; Duloxetine Hydrochloride; Humans; Male; Parkinsonian Disorders; Piperazines; Receptors, Serotonin, 5-HT2; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Thiazoles; Thiophenes; Urinary Incontinence | 2009 |
Highly enantioselective Friedel-Crafts reaction of thiophenes with glyoxylates: formal synthesis of duloxetine.
Topics: Acetates; Duloxetine Hydrochloride; Glyoxylates; Organometallic Compounds; Stereoisomerism; Substrate Specificity; Thiophenes | 2009 |
Stress degradation studies on duloxetine hydrochloride and development of an RP-HPLC method for its determination in capsule formulation.
Topics: Capsules; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Stability; Duloxetine Hydrochloride; Hydrogen-Ion Concentration; Hydrolysis; Oxidation-Reduction; Reproducibility of Results; Sensitivity and Specificity; Thiophenes | 2009 |
Duloxetine related binge eating behaviors: a case report.
Topics: Adult; Antidepressive Agents; Binge-Eating Disorder; Depression; Duloxetine Hydrochloride; Female; Humans; Thiophenes | 2009 |
Duloxetine for pathological laughing and crying.
Topics: Affective Symptoms; Amyotrophic Lateral Sclerosis; Crying; Duloxetine Hydrochloride; Female; Humans; Laughter; Middle Aged; Thiophenes | 2009 |
Synthesis of 1,1-[1-naphthyloxy-2-thiophenyl]-2-methylaminomethylcyclopropanes and their evaluation as inhibitors of serotonin, norepinephrine, and dopamine transporters.
Topics: Animals; Cyclopropanes; Dopamine Plasma Membrane Transport Proteins; Duloxetine Hydrochloride; Humans; Norepinephrine Plasma Membrane Transport Proteins; Plasma Membrane Neurotransmitter Transport Proteins; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Thiophenes | 2009 |
First preliminary results of a single case report: duloxetine might improve some symptoms of attention-deficit hyperactivity disorder.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Dopamine Uptake Inhibitors; Duloxetine Hydrochloride; Female; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2010 |
Use of duloxetine in pregnancy and lactation.
Topics: Adult; Duloxetine Hydrochloride; Female; Humans; Infant; Lactation; Maternal-Fetal Exchange; Milk, Human; Pregnancy; Thiophenes | 2009 |
[Mirtazapine-associated hepatotoxicity].
Topics: Antidepressive Agents; Chemical and Drug Induced Liver Injury; Cholestasis; Depressive Disorder; Drug Interactions; Duloxetine Hydrochloride; Humans; Kidney Failure, Chronic; Male; Mianserin; Middle Aged; Mirtazapine; Nephrosclerosis; Thiophenes | 2010 |
Relationship between TSH levels in the normal range and short-term duloxetine efficacy.
Topics: Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Meta-Analysis as Topic; Middle Aged; Personality Inventory; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Thiophenes; Thyrotropin; Treatment Outcome | 2010 |
[Psycho- and pharmacotherapy of depressions. So you combine correctly].
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Behavior Therapy; Combined Modality Therapy; Cyclohexanols; Depressive Disorder; Dopamine Uptake Inhibitors; Duloxetine Hydrochloride; Humans; Mianserin; Middle Aged; Mirtazapine; Psychotherapy; Selective Serotonin Reuptake Inhibitors; Thiophenes; Venlafaxine Hydrochloride | 2009 |
Duloxetine related effects of brain structure on a patient of major depressive disorder with panic disorder.
Topics: Adult; Antidepressive Agents; Brain; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Male; Panic Disorder; Thiophenes | 2010 |
What makes patients with fibromyalgia feel better? Correlations between Patient Global Impression of Improvement and changes in clinical symptoms and function: a pooled analysis of 4 randomized placebo-controlled trials of duloxetine.
Topics: Antidepressive Agents; Duloxetine Hydrochloride; Fibromyalgia; Humans; Pain; Pain Measurement; Randomized Controlled Trials as Topic; Surveys and Questionnaires; Thiophenes | 2009 |
Tinnitus in postherpetic neuralgia.
Topics: Acyclovir; Adrenergic Uptake Inhibitors; Aged; Antiviral Agents; Cranial Nerves; Duloxetine Hydrochloride; Female; Follow-Up Studies; Functional Laterality; Humans; Neuralgia, Postherpetic; Thiophenes; Tinnitus | 2010 |
Comparison of milnacipran, duloxetine and pregabalin in the formalin pain test and in a model of stress-induced ultrasonic vocalizations in rats.
Topics: Adrenergic Uptake Inhibitors; Analgesics; Analysis of Variance; Animals; Cyclopropanes; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Electroshock; Formaldehyde; gamma-Aminobutyric Acid; Male; Milnacipran; Pain; Pain Measurement; Pregabalin; Rats; Rats, Sprague-Dawley; Stress, Physiological; Thiophenes; Vocalization, Animal | 2010 |
Major Depressive Disorder in recovery and neuropsychological functioning: effects of selective serotonin reuptake inhibitor and dual inhibitor depression treatments on residual cognitive deficits in patients with Major Depressive Disorder in recovery.
Topics: Adult; Antidepressive Agents; Citalopram; Cognition Disorders; Controlled Clinical Trials as Topic; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Personality Inventory; Reference Values; Selective Serotonin Reuptake Inhibitors; Thiophenes; Wechsler Scales | 2010 |
How are women with SUI-symptoms treated with duloxetine in real life practice? - preliminary results from a large observational study in Germany.
Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Duloxetine Hydrochloride; Female; Germany; Humans; Middle Aged; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2009 |
Evaluation of anti-obesity activity of duloxetine in comparison with sibutramine along with its anti-depressant activity: an experimental study in obese rats.
Topics: Adiposity; Animals; Anti-Obesity Agents; Antidepressive Agents; Appetite Regulation; Blood Pressure; Body Temperature Regulation; Body Weight; Cyclobutanes; Depression; Diet; Drug Evaluation, Preclinical; Drug Therapy, Combination; Duloxetine Hydrochloride; Male; Motor Activity; Obesity; Rats; Rats, Sprague-Dawley; Satiety Response; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2009 |
Duloxetine related hypersexuality: a case report.
Topics: Adult; Duloxetine Hydrochloride; Humans; Hypertension; Male; Selective Serotonin Reuptake Inhibitors; Sexual Dysfunctions, Psychological; Stroke; Thiophenes | 2010 |
Duloxetine in treating medically unexplained pain and Raynaud's phenomenon.
Topics: Antidepressive Agents; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Off-Label Use; Pain; Raynaud Disease; Thiophenes; Treatment Outcome | 2009 |
Determination of duloxetine hydrochloride in the presence of process and degradation impurities by a validated stability-indicating RP-LC method.
Topics: Antidepressive Agents; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Contamination; Drug Stability; Duloxetine Hydrochloride; Hydrogen-Ion Concentration; Hydrolysis; Oxidation-Reduction; Reproducibility of Results; Technology, Pharmaceutical; Thiophenes | 2010 |
Anxiety does not predict response to duloxetine in major depression: results of a pooled analysis of individual patient data from 11 placebo-controlled trials.
Topics: Adult; Antidepressive Agents; Anxiety Disorders; Comorbidity; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Meta-Analysis as Topic; Middle Aged; Personality Inventory; Prognosis; Psychometrics; Randomized Controlled Trials as Topic; Retrospective Studies; Thiophenes; Treatment Outcome | 2010 |
Recurrent episodes of serotonin-reuptake inhibitor-mediated hyponatremia in an elderly patient.
Topics: Aged; Antidepressive Agents; Depression; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Inappropriate ADH Syndrome; Recurrence; Selective Serotonin Reuptake Inhibitors; Sodium; Thiophenes | 2009 |
Pharmacological treatment of fibromyalgia syndrome: new developments.
Topics: Age Factors; Analgesics, Opioid; Calcium Channel Blockers; Clinical Trials as Topic; Cognitive Behavioral Therapy; Combined Modality Therapy; Dopamine Agonists; Duloxetine Hydrochloride; Exercise; Exercise Therapy; Fatigue; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Pain; Pain Measurement; Pain Threshold; Pregabalin; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Research Design; Self Care; Thiophenes; Treatment Outcome | 2010 |
Drugs to treat fibromyalgia - the transatlantic difference.
Topics: Adrenergic Uptake Inhibitors; Analgesics; Cyclopropanes; Drug Approval; Duloxetine Hydrochloride; European Union; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Milnacipran; Off-Label Use; Pregabalin; Thiophenes; United States; United States Food and Drug Administration | 2010 |
A case study of salami slicing: pooled analyses of duloxetine for depression.
Topics: Advertising; Antidepressive Agents; Clinical Trials as Topic; Conflict of Interest; Depressive Disorder, Major; Drug Industry; Duloxetine Hydrochloride; Humans; Meta-Analysis as Topic; Publishing; Thiophenes; Treatment Outcome | 2010 |
[Treatment of neuropathies].
Topics: Adjuvants, Immunologic; Adrenergic Uptake Inhibitors; Amines; Analgesics; Antioxidants; Capsaicin; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Polyneuropathies; Pregabalin; Sensory System Agents; Thiamine; Thioctic Acid; Thiophenes | 2010 |
Duloxetine-modulating effects of brain structure in major depressive disorder with panic disorder.
Topics: Adrenergic Uptake Inhibitors; Adult; Brain; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Magnetic Resonance Imaging; Male; Panic Disorder; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2010 |
[Expel the fear of pain. Breaking of chronicity by re-learning].
Topics: Analgesics; Clinical Trials as Topic; Diabetic Neuropathies; Duloxetine Hydrochloride; Fear; Humans; Pain; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Treatment Outcome | 2009 |
Unexplained high fever in an elderly patient treated with clonidine, duloxetine, and atorvastatin.
Topics: Aged; Antidepressive Agents; Antihypertensive Agents; Atorvastatin; Body Temperature; Clonidine; Drug Interactions; Duloxetine Hydrochloride; Female; Fever of Unknown Origin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Polypharmacy; Pyrroles; Thiophenes; Time Factors | 2009 |
The market lifecycle of duloxetine for urinary incontinence in Norway.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Databases, Factual; Drug Prescriptions; Duloxetine Hydrochloride; Female; Humans; Infant; Infant, Newborn; Medicine; Middle Aged; Norway; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress; Young Adult | 2010 |
Serotonin syndrome in an octogenarian after switch from fluoxetine to duloxetine.
Topics: Aged, 80 and over; Duloxetine Hydrochloride; Fluoxetine; Humans; Male; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Thiophenes | 2009 |
Long-Term duloxetine treatment normalizes altered brain-derived neurotrophic factor expression in serotonin transporter knockout rats through the modulation of specific neurotrophin isoforms.
Topics: Animals; Brain-Derived Neurotrophic Factor; Duloxetine Hydrochloride; Frontal Lobe; Gene Expression Regulation; Hippocampus; Nerve Growth Factors; Prefrontal Cortex; Rats; Rats, Transgenic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Thiophenes | 2010 |
Cost effectiveness of pregabalin in the treatment of fibromyalgia from a UK perspective.
Topics: Adult; Amines; Amitriptyline; Analgesics; Antidepressive Agents; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Drug Costs; Duloxetine Hydrochloride; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Markov Chains; Models, Econometric; Pregabalin; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Thiophenes; Tramadol; United Kingdom | 2010 |
[The effects of duloxetine on beta-actin stress response in rat brain].
Topics: Actins; Adrenergic Uptake Inhibitors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Blotting, Western; Duloxetine Hydrochloride; Male; Mitogen-Activated Protein Kinase 1; Neuronal Plasticity; Norepinephrine; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Thiophenes | 2010 |
Management of depression in the presence of pain symptoms.
Topics: Antidepressive Agents; Brain; Chronic Disease; Clinical Trials as Topic; Combined Modality Therapy; Comorbidity; Cyclohexanols; Cyclopropanes; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Fibromyalgia; Humans; Milnacipran; Mind-Body Relations, Metaphysical; Norepinephrine; Pain; Psychotherapy; Serotonin; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2010 |
Analytic model comparing the cost utility of TVT versus duloxetine in women with urinary stress incontinence.
Topics: Cost-Benefit Analysis; Duloxetine Hydrochloride; Female; Humans; Markov Chains; Models, Statistical; Quality-Adjusted Life Years; Selective Serotonin Reuptake Inhibitors; Sensitivity and Specificity; Suburethral Slings; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2010 |
[Conservative management of postoperative urinary incontinence in men].
Topics: Adrenergic Uptake Inhibitors; Biofeedback, Psychology; Combined Modality Therapy; Duloxetine Hydrochloride; Electric Stimulation Therapy; Exercise Therapy; Humans; Magnetic Field Therapy; Male; Postoperative Complications; Prostatectomy; Thiophenes; Urinary Incontinence, Stress | 2010 |
Comparison of neurogenic effects of fluoxetine, duloxetine and running in mice.
Topics: Animals; Behavior, Animal; Cell Proliferation; Cell Survival; Duloxetine Hydrochloride; Female; Fluoxetine; Hippocampus; Mice; Mice, Inbred C57BL; Motor Activity; Neurogenesis; Neuronal Plasticity; Neurons; Physical Conditioning, Animal; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2010 |
[Focus on treatment success of depressed patients. Early and significant pain reduction improves chances for remission].
Topics: Antidepressive Agents; Depressive Disorder; Duloxetine Hydrochloride; Humans; Long-Term Care; Pain; Thiophenes | 2010 |
Effects of selective serotonin reuptake and dual serotonergic-noradrenergic reuptake treatments on attention and executive functions in patients with major depressive disorder.
Topics: Adrenergic Uptake Inhibitors; Adult; Attention Deficit Disorder with Hyperactivity; Citalopram; Cognition Disorders; Depressive Disorder, Major; Duloxetine Hydrochloride; Executive Function; Female; Humans; Male; Neuropsychological Tests; Psychometrics; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Young Adult | 2010 |
Correction of venlafaxine- and duloxetine-induced transaminase elevations with desvenlafaxine in a patient with Gilbert's syndrome.
Topics: Adult; Aminoacyltransferases; Antidepressive Agents; Cyclohexanols; Desvenlafaxine Succinate; Duloxetine Hydrochloride; Gilbert Disease; Humans; Male; Thiophenes; Venlafaxine Hydrochloride | 2010 |
Profile of adverse events with duloxetine treatment: a pooled analysis of placebo-controlled studies.
Topics: Age Factors; Antidepressive Agents; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Fatigue; Female; Humans; Male; Middle Aged; Nausea; Racial Groups; Randomized Controlled Trials as Topic; Sex Factors; Thiophenes | 2010 |
The predictive value of pre-treatment cystometry in the outcome of women with mixed incontinence treated with duloxetine.
Topics: Adult; Aged; Aged, 80 and over; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Predictive Value of Tests; Quality of Life; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Surveys and Questionnaires; Thiophenes; Treatment Outcome; Urinary Bladder, Overactive; Urinary Incontinence; Urodynamics | 2010 |
[Duloxetine in the treatment of chronic migraine].
Topics: Adult; Antidepressive Agents; Blinking; Dose-Response Relationship, Drug; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Migraine Disorders; Pain Measurement; Thiophenes; Treatment Outcome | 2010 |
Cost-effectiveness of duloxetine: the Stress Urinary Incontinence Treatment (SUIT) study.
Topics: Adrenergic Uptake Inhibitors; Cohort Studies; Cost-Benefit Analysis; Duloxetine Hydrochloride; Female; Health Resources; Health Status Indicators; Humans; Internationality; Middle Aged; Multivariate Analysis; Outcome Assessment, Health Care; Propensity Score; Prospective Studies; Quality of Life; Quality-Adjusted Life Years; Regression Analysis; Thiophenes; United Kingdom; Urinary Incontinence, Stress; Women's Health | 2010 |
Lymphocytic colitis under treatment with duloxetine.
Topics: Aged, 80 and over; Colitis, Lymphocytic; Duloxetine Hydrochloride; Female; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2010 |
Selective potentiation of gabapentin-mediated antinociception in the rat formalin test by the nicotinic acetylcholine receptor agonist ABT-594.
Topics: Amines; Analgesics; Animals; Azetidines; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Duloxetine Hydrochloride; Exploratory Behavior; Gabapentin; gamma-Aminobutyric Acid; Male; Mecamylamine; Morphine; Nicotinic Agonists; Nicotinic Antagonists; Pain; Pain Measurement; Pyridines; Rats; Rats, Sprague-Dawley; Thiophenes | 2010 |
Artifactual formylation of the secondary amine of duloxetine hydrochloride by acetonitrile in the presence of titanium dioxide: implications for HPLC method development.
Topics: Acetonitriles; Amines; Artifacts; Chromatography, High Pressure Liquid; Deuterium; Drug Contamination; Drug Stability; Duloxetine Hydrochloride; Excipients; Light; Sonication; Technology, Pharmaceutical; Thiophenes; Titanium | 2010 |
Non-length-dependent small fibre neuropathy. Confocal microscopy study of the corneal innervation.
Topics: Adult; Amines; Amitriptyline; Analgesics; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Biopsy; Cornea; Crohn Disease; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Electrophysiology; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Microscopy, Confocal; Middle Aged; Nerve Endings; Nerve Fibers; Peripheral Nervous System Diseases; Sensation Disorders; Sjogren's Syndrome; Skin; Thiophenes; Trigeminal Nerve | 2010 |
Long lasting pain hypersensitivity following ligation of the tendon of the masseter muscle in rats: a model of myogenic orofacial pain.
Topics: Adrenergic Uptake Inhibitors; Analgesics; Animals; Disease Models, Animal; Duloxetine Hydrochloride; Facial Pain; Hyperalgesia; Ligation; Male; Masseter Muscle; Neuroglia; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tendons; Thiophenes; Trigeminal Nucleus, Spinal | 2010 |
Alpha2-adrenoceptor blockade potentiates the effect of duloxetine on sneeze induced urethral continence reflex in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Drug Synergism; Duloxetine Hydrochloride; Female; Idazoxan; Rats; Rats, Sprague-Dawley; Reflex; Selective Serotonin Reuptake Inhibitors; Sneezing; Thiophenes; Urethra; Urinary Incontinence, Stress; Yohimbine | 2010 |
Study on the binding of chiral drug duloxetine hydrochloride to human serum albumin.
Topics: Binding, Competitive; Duloxetine Hydrochloride; Electrophoresis, Capillary; Humans; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Stereoisomerism; Thiophenes; Tyrosine | 2010 |
Changes in opioid use and healthcare costs among U.S. patients with diabetic peripheral neuropathic pain treated with duloxetine compared with other therapies.
Topics: Adolescent; Adult; Analgesics; Analgesics, Opioid; Diabetic Neuropathies; Drug Substitution; Duloxetine Hydrochloride; Female; Health Care Costs; Humans; Male; Middle Aged; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes; United States; Young Adult | 2010 |
A subtle grey-matter increase in first-episode, drug-naive major depressive disorder with panic disorder after 6 weeks' duloxetine therapy.
Topics: Antidepressive Agents; Brain; Cerebellum; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Frontal Lobe; Humans; Magnetic Resonance Imaging; Male; Panic Disorder; Psychiatric Status Rating Scales; Temporal Lobe; Thiophenes; Time Factors; Treatment Outcome | 2011 |
Effects of duloxetine treatment on brain response to painful stimulation in major depressive disorder.
Topics: Adult; Brain; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Pain; Pain Measurement; Thiophenes; Treatment Outcome | 2010 |
Characterization of glutathione conjugates of duloxetine by mass spectrometry and evaluation of in silico approaches to rationalize the site of conjugation for thiophene containing drugs.
Topics: Animals; Binding Sites; Cytosol; Drug Design; Duloxetine Hydrochloride; Glutathione; Glutathione Transferase; Humans; Mass Spectrometry; Microsomes, Liver; Molecular Structure; Quinidine; Rationalization; Rats; Structure-Activity Relationship; Theophylline; Thiophenes | 2010 |
Block of neuronal Na+ channels by antidepressant duloxetine in a state-dependent manner.
Topics: Antidepressive Agents; Cell Line; Duloxetine Hydrochloride; Humans; Mutation; NAV1.7 Voltage-Gated Sodium Channel; Sodium Channel Blockers; Sodium Channels; Thiophenes | 2010 |
Cost effectiveness of escitalopram versus SNRIs in second-step treatment of major depressive disorder in Sweden.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents, Second-Generation; Citalopram; Cyclohexanols; Decision Support Techniques; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Markov Chains; Outcome Assessment, Health Care; Quality-Adjusted Life Years; Recurrence; Remission Induction; Selective Serotonin Reuptake Inhibitors; Sweden; Thiophenes; Venlafaxine Hydrochloride | 2010 |
A rapid, Web-based method for obtaining patient views on effects and side-effects of antidepressants.
Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Cyclohexanols; Data Collection; Desvenlafaxine Succinate; Duloxetine Hydrochloride; Fatigue; Fluvoxamine; Humans; Internet; Lethargy; Mianserin; Mirtazapine; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Sleep Stages; Thiophenes; Venlafaxine Hydrochloride | 2011 |
Initial duloxetine prescription dose and treatment adherence and persistence in patients with major depressive disorder.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Depressive Disorder, Major; Drug Prescriptions; Duloxetine Hydrochloride; Female; Humans; Male; Managed Care Programs; Medical Records; Medication Adherence; Middle Aged; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Young Adult | 2010 |
Duloxetine hepatotoxicity: a case-series from the drug-induced liver injury network.
Topics: Adult; Antidepressive Agents; Biopsy; Chemical and Drug Induced Liver Injury; Duloxetine Hydrochloride; Female; Humans; Liver; Male; Middle Aged; Prospective Studies; Thiophenes | 2010 |
Opioid use and healthcare costs among patients with DPNP initiating duloxetine versus other treatments.
Topics: Adolescent; Adult; Analgesics; Analgesics, Opioid; Case-Control Studies; Cohort Studies; Cost-Benefit Analysis; Duloxetine Hydrochloride; Female; Health Care Costs; Humans; Male; Middle Aged; Neuralgia; Retrospective Studies; Thiophenes; Young Adult | 2010 |
Effect of adjunctive duloxetine on the plasma concentrations of clozapine, olanzapine, and risperidone in patients with psychotic disorders.
Topics: Adult; Benzodiazepines; Clozapine; Drug Interactions; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Olanzapine; Psychotic Disorders; Risperidone; Thiophenes; Young Adult | 2010 |
A case of milnacipran-related sweating alleviated by duloxetine substitution.
Topics: Cyclopropanes; Drug Substitution; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Middle Aged; Milnacipran; Sweating; Thiophenes | 2010 |
[Design, synthesis and antidepressive activity of duloxetine derivatives].
Topics: Animals; Antidepressive Agents; Duloxetine Hydrochloride; Hindlimb Suspension; Male; Mice; Mice, Inbred ICR; Molecular Structure; Serotonin 5-HT1 Receptor Antagonists; Structure-Activity Relationship; Swimming; Thiophenes | 2010 |
Long-term safety of duloxetine during open-label compassionate use treatment of patients who completed previous duloxetine clinical trials.
Topics: Adult; Antidepressive Agents; Compassionate Use Trials; Depressive Disorder, Major; Drug-Related Side Effects and Adverse Reactions; Duloxetine Hydrochloride; Female; Humans; Male; Medication Adherence; Middle Aged; Outcome Assessment, Health Care; Thiophenes; Time | 2010 |
Prediction of repeat-dose occupancy from single-dose data: characterisation of the relationship between plasma pharmacokinetics and brain target occupancy.
Topics: Adult; Benzylamines; Brain; Dose-Response Relationship, Drug; Drug Administration Schedule; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Models, Biological; Osmolar Concentration; Positron-Emission Tomography; Predictive Value of Tests; Radiochemistry; Thiophenes | 2011 |
Is duloxetine useful for central neuropathic pain?
Topics: Duloxetine Hydrochloride; Female; Humans; Male; Neuralgia; Spinal Cord Injuries; Stroke; Thiophenes | 2011 |
[The weeping patient].
Topics: Antidepressive Agents; Crying; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Physician-Patient Relations; Primary Health Care; Thiophenes | 2010 |
Factors associated with duloxetine treatment among patients with major depressive disorder in Veterans Health Administration: a retrospective study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Retrospective Studies; Risk Factors; Socioeconomic Factors; Thiophenes; United States; United States Department of Veterans Affairs; Veterans Health; Young Adult | 2010 |
Increased aripiprazole concentrations in an HIV-positive male concurrently taking duloxetine, darunavir, and ritonavir.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Anxiety; Aripiprazole; Cytochrome P-450 Enzyme Inhibitors; Darunavir; Depression; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; HIV Infections; HIV Protease Inhibitors; Humans; Male; Piperazines; Quinolones; Ritonavir; Sulfonamides; Thiophenes | 2010 |
Analysis of duloxetine hydrochloride and its related compounds in pharmaceutical dosage forms and in vitro dissolution studies by stability indicating UPLC.
Topics: Chromatography, High Pressure Liquid; Dosage Forms; Drug Stability; Duloxetine Hydrochloride; Solubility; Thiophenes | 2010 |
Duloxetine in major depressed patients resistant to SSRIs and/or venlafaxine.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depressive Disorder, Major; Drug Resistance; Duloxetine Hydrochloride; Humans; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2010 |
The effect of coadministration of duloxetine on steady-state serum concentration of risperidone and aripiprazole: a study based on therapeutic drug monitoring data.
Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Aripiprazole; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Piperazines; Quinolones; Risperidone; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2010 |
Halothane-anesthetized rabbit: a new experimental model to test the effects of besipirdine and duloxetine on lower urinary tract function.
Topics: Anesthesia; Anesthetics; Animals; Atomoxetine Hydrochloride; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Electromyography; Female; Halothane; Humans; Indoles; Muscle, Smooth; Norepinephrine; Prazosin; Propylamines; Pyridines; Rabbits; Retrospective Studies; Thiophenes; Urinary Tract; Urinary Tract Infections; Urodynamics | 2011 |
Rapid HPLC method for the simultaneous monitoring of duloxetine, venlaflaxine, fluoxetine and paroxetine in biofluids.
Topics: Chromatography, High Pressure Liquid; Cyclohexanols; Duloxetine Hydrochloride; Fluoxetine; Humans; Limit of Detection; Paroxetine; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Sensitivity and Specificity; Thiophenes; Venlafaxine Hydrochloride | 2009 |
Evaluation of healthcare resource utilization and costs in employees with pain associated with diabetic peripheral neuropathy treated with pregabalin or duloxetine.
Topics: Adolescent; Adult; Age Factors; Analgesics; Comorbidity; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Health Services; Humans; Insurance Claim Review; Male; Middle Aged; Pain; Pregabalin; Sex Factors; Socioeconomic Factors; Thiophenes; Young Adult | 2010 |
A case of venlafaxine-induced bruxism alleviated by duloxetine substitution.
Topics: Aged; Antidepressive Agents; Bruxism; Cyclohexanols; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Thiophenes; Venlafaxine Hydrochloride | 2011 |
Aripiprazole augmentation induced hypertension in major depressive disorder: a case report.
Topics: Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Depressive Disorder, Major; Drug Synergism; Duloxetine Hydrochloride; Female; Humans; Hypertension; Middle Aged; Piperazines; Quinolones; Thiophenes | 2011 |
Improvement with duloxetine in primary progressive freezing gait.
Topics: Brain; Disease Progression; Dopamine Uptake Inhibitors; Drug Administration Schedule; Duloxetine Hydrochloride; Gait Disorders, Neurologic; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Thiophenes | 2010 |
[Effective treatment of depression. Early reduction of painful concomitant symptoms increases the probability of remission].
Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Early Diagnosis; General Practice; Humans; Pain; Quality of Life; Somatoform Disorders; Thiophenes | 2010 |
[Interview with Dr. Armin Spingler. Management of depression in family practice].
Topics: Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; General Practice; Humans; Medication Adherence; Pain; Somatoform Disorders; Thiophenes | 2010 |
Combination of lithium and duloxetine in 2 depressed patients refractory to duloxetine monotherapy.
Topics: Aged; Antimanic Agents; Depressive Disorder; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Hospitalization; Humans; Lithium Carbonate; Male; Outpatients; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2011 |
Serotonin syndrome after discontinuation of olanzapine in a combined treatment with duloxetine -- case report.
Topics: Benzodiazepines; Depressive Disorder; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Olanzapine; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Thiophenes | 2011 |
False conclusions regarding duloxetine's purported efficacy in pain among depressed patients.
Topics: Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Pain; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2010 |
Coma after overdose with duloxetine.
Topics: Adrenergic Uptake Inhibitors; Coma; Drug Overdose; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Urinary Retention | 2011 |
On the three-arm non-inferiority trial including a placebo with a prespecified margin.
Topics: Algorithms; Antidepressive Agents; Computer Simulation; Confidence Intervals; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Humans; Models, Statistical; Monte Carlo Method; Multicenter Studies as Topic; Normal Distribution; Paroxetine; Placebos; Randomized Controlled Trials as Topic; Sample Size; Thiophenes; Treatment Outcome | 2011 |
Burning mouth syndrome responsive to duloxetine: a case report.
Topics: Aged; Burning Mouth Syndrome; Duloxetine Hydrochloride; Female; Humans; Male; Neuropsychological Tests; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2011 |
Adherence and persistence with duloxetine and hospital utilization in patients with major depressive disorder.
Topics: Adult; Antidepressive Agents; Databases, Factual; Depressive Disorder, Major; Duloxetine Hydrochloride; Hospitalization; Humans; Medication Adherence; Middle Aged; Thiophenes; Time Factors; Young Adult | 2011 |
Treatment patterns associated with Duloxetine and Venlafaxine use for Major Depressive Disorder.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; Cyclohexanols; Depressive Disorder, Major; Drug Costs; Duloxetine Hydrochloride; Female; Health Care Costs; Humans; Male; Middle Aged; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2011 |
Measurement-based care in psychiatric practice: a policy framework for implementation.
Topics: Adult; Antidepressive Agents; Cooperative Behavior; Depressive Disorder, Major; Disease Management; Duloxetine Hydrochloride; Female; Health Plan Implementation; Humans; Interdisciplinary Communication; Medication Adherence; Outcome and Process Assessment, Health Care; Standard of Care; Surveys and Questionnaires; Thiophenes | 2011 |
Hypogonadism and gynecomastia with duloxetine.
Topics: Bulimia Nervosa; Depressive Disorder, Major; Duloxetine Hydrochloride; Gynecomastia; Humans; Hypogonadism; Male; Mastectomy; Selective Serotonin Reuptake Inhibitors; Thiophenes; Young Adult | 2011 |
Medication adherence and healthcare costs among patients with diabetic peripheral neuropathic pain initiating duloxetine versus pregabalin.
Topics: Adolescent; Adult; Analgesics; Cohort Studies; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Health Care Costs; Humans; Male; Medication Adherence; Middle Aged; Neuralgia; Pregabalin; Retrospective Studies; Thiophenes; Young Adult | 2011 |
Atypical Stevens-Johnson syndrome in an adolescent treated with duloxetine.
Topics: Adolescent; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Male; Stevens-Johnson Syndrome; Thiophenes | 2011 |
In vitro and in vivo evaluation of the effects of duloxetine on P-gp function.
Topics: Adrenergic beta-Antagonists; Adult; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Drug Interactions; Drug Resistance; Duloxetine Hydrochloride; Female; Humans; Male; Propanolamines; Thiophenes; Young Adult | 2010 |
Pathologic grooming behavior: facial dermatillomania.
Topics: Binge-Eating Disorder; Body Dysmorphic Disorders; Cognitive Behavioral Therapy; Depression; Disruptive, Impulse Control, and Conduct Disorders; Duloxetine Hydrochloride; Exercise; Face; Female; Hair; Humans; Middle Aged; Selective Serotonin Reuptake Inhibitors; Skin Care; Thiophenes | 2011 |
Duloxetine. Also avoid its use in recurrent depression.
Topics: Antidepressive Agents; Depression; Duloxetine Hydrochloride; Humans; Recurrence; Thiophenes | 2010 |
Duloxetine transfer across the placenta during pregnancy and into milk during lactation.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Lactation; Milk, Human; Placenta; Pregnancy; Thiophenes | 2011 |
Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain?
Topics: Analgesics; Animals; Antidepressive Agents; Clomipramine; Cyclopropanes; Diabetes Mellitus, Experimental; Disease Models, Animal; Duloxetine Hydrochloride; Hyperalgesia; Male; Milnacipran; Naloxone; Neuralgia; Rats; Rats, Sprague-Dawley; Thiophenes | 2011 |
Highly enantioselective bioreduction of N-methyl-3-oxo-3-(thiophen-2-yl) propanamide for the production of (S)-duloxetine.
Topics: DNA, Fungal; DNA, Ribosomal; Duloxetine Hydrochloride; Genes, rRNA; Molecular Sequence Data; Oxidation-Reduction; Rhodotorula; RNA, Fungal; RNA, Ribosomal, 18S; Sequence Analysis, DNA; Stereoisomerism; Thiophenes | 2011 |
A spinal mechanism of action for duloxetine in a rat model of painful diabetic neuropathy.
Topics: Amphetamines; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Hyperalgesia; Ketanserin; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Thiophenes | 2011 |
Retrospective audit on tolerability and efficacy of duloxetine for stress urinary incontinence.
Topics: Duloxetine Hydrochloride; Female; Humans; Middle Aged; Nausea; Patient Education as Topic; Patient Selection; Retrospective Studies; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2011 |
Duloxetine-related panic attacks.
Topics: Alprazolam; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Middle Aged; Oxazepam; Panic Disorder; Thiazepines; Thiophenes | 2011 |
Reinforcement of irritability during therapy with benzodiazepines.
Topics: Adult; Antidepressive Agents; Anxiety; Benzodiazepines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Tolerance; Duloxetine Hydrochloride; Humans; Hypnotics and Sedatives; Irritable Mood; Life Change Events; Male; Oxazepam; Pyridines; Self Medication; Thiophenes; Zolpidem | 2011 |
A chemoenzymatic dynamic kinetic resolution approach to enantiomerically pure (R)- and (S)-duloxetine.
Topics: Duloxetine Hydrochloride; Fungal Proteins; Kinetics; Lipase; Ruthenium; Stereoisomerism; Thiophenes | 2011 |
Duloxetine in the treatment of adolescents with attention deficit/hyperactivity disorder: an open-label study.
Topics: Adolescent; Age Factors; Appetite; Attention Deficit Disorder with Hyperactivity; Child; Duloxetine Hydrochloride; Humans; Nausea; Self Report; Thiophenes; Treatment Outcome | 2011 |
Average daily dose, medication adherence, and healthcare costs among commercially-insured patients with fibromyalgia treated with duloxetine.
Topics: Adult; Antidepressive Agents; Duloxetine Hydrochloride; Female; Fibromyalgia; Health Care Costs; Humans; Insurance Coverage; Insurance, Health; Male; Middle Aged; Patient Compliance; Retrospective Studies; Thiophenes | 2011 |
Duloxetine use in painful conditions.
Topics: Analgesia; Analgesics; Animals; Antidepressive Agents; Chronic Disease; Disease Models, Animal; Duloxetine Hydrochloride; Humans; Low Back Pain; Osteoarthritis; Pain; Retrospective Studies; Thiophenes; Treatment Outcome | 2011 |
Treatment adherence and persistence with duloxetine, venlafaxine XR, and escitalopram among patients with major depressive disorder and chronic pain-related diseases.
Topics: Adolescent; Adult; Algorithms; Antidepressive Agents; Chronic Disease; Citalopram; Cyclohexanols; Depressive Disorder, Major; Dosage Forms; Duloxetine Hydrochloride; Female; Humans; Male; Medication Adherence; Middle Aged; Pain; Retrospective Studies; Somatoform Disorders; Thiophenes; Venlafaxine Hydrochloride; Young Adult | 2011 |
Postprostatectomy established stress urinary incontinence treated with duloxetine.
Topics: Aged; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Prostatectomy; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence, Stress | 2011 |
Plasma kynurenine levels are elevated in suicide attempters with major depressive disorder.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Cytokines; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Hypericum; Impulsive Behavior; Inflammation; Kynurenine; Male; Middle Aged; Neopterin; Phytotherapy; Recurrence; Serotonin; Smoking; Suicide, Attempted; Thiophenes; Tryptophan; Young Adult | 2011 |
Duloxetine-induced tako-tsubo cardiomyopathy: implications for preventing a broken heart.
Topics: Duloxetine Hydrochloride; Humans; Selective Serotonin Reuptake Inhibitors; Takotsubo Cardiomyopathy; Thiophenes | 2011 |
"Tako-tsubo" cardiomyopathy and duloxetine use.
Topics: Aged; Duloxetine Hydrochloride; Electrocardiography; Female; Humans; Myocardial Infarction; Selective Serotonin Reuptake Inhibitors; Takotsubo Cardiomyopathy; Thiophenes | 2011 |
Factors associated with pain medication selection among patients diagnosed with diabetic peripheral neuropathic pain: a retrospective study.
Topics: Analgesics; Comorbidity; Costs and Cost Analysis; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Health Services; Humans; Insurance Claim Review; Male; Middle Aged; Pain; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Socioeconomic Factors; Thiophenes; United States | 2011 |
Health care costs in patients with fibromyalgia on pregabalin vs. duloxetine.
Topics: Adolescent; Adult; Aged; Analgesics; Duloxetine Hydrochloride; Female; Fibromyalgia; gamma-Aminobutyric Acid; Health Care Costs; Humans; Insurance Claim Review; Male; Middle Aged; Pregabalin; Thiophenes; Young Adult | 2012 |
[Non-surgical treatment of female incontinence].
Topics: Antidepressive Agents; Cholinergic Antagonists; Combined Modality Therapy; Duloxetine Hydrochloride; Estrogen Replacement Therapy; Exercise Therapy; Female; Humans; Thiophenes; Urinary Incontinence, Stress; Urinary Incontinence, Urge; Weight Loss | 2011 |
Cost effectiveness of duloxetine in the treatment of fibromyalgia in the United States.
Topics: Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Contraindications; Cost-Benefit Analysis; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Markov Chains; Medication Adherence; Middle Aged; Models, Economic; Quality-Adjusted Life Years; Selective Serotonin Reuptake Inhibitors; Thiophenes; United States | 2011 |
Retrospective chart review of duloxetine and pregabalin in the treatment of painful neuropathy.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Dopamine Uptake Inhibitors; Duloxetine Hydrochloride; Female; Follow-Up Studies; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pregabalin; Retrospective Studies; Thiophenes; Treatment Outcome | 2011 |
Health care costs in patients with painful diabetic peripheral neuropathy prescribed pregabalin or duloxetine.
Topics: Adolescent; Adult; Aged; Analgesics; Cohort Studies; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Health Care Costs; Health Services; Humans; Male; Managed Care Programs; Middle Aged; Pregabalin; Thiophenes; United States | 2012 |
Duloxetine-related growth of putamen and brainstem in first-onset drug-naive major depressive disorder with panic disorder: a case series.
Topics: Adult; Antidepressive Agents; Brain Stem; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Magnetic Resonance Imaging; Male; Organ Size; Panic Disorder; Putamen; Thiophenes | 2011 |
Duloxetine-induced subcortical growth in a patient with major depressive disorder and panic disorder.
Topics: Adult; Antidepressive Agents; Brain Stem; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Male; Organ Size; Panic Disorder; Putamen; Thiophenes | 2011 |
Duloxetine for depression and the incidence of hepatic events in adults.
Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Cohort Studies; Depression; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Retrospective Studies; Thiophenes; Young Adult | 2011 |
Interaction between adalimumab with concurrent pregabalin and duloxetine administration in a psoriasis patient with diabetic peripheral neuropathy.
Topics: Adalimumab; Analgesics; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Drug Interactions; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Pregabalin; Psoriasis; Selective Serotonin Reuptake Inhibitors; Thiophenes; Young Adult | 2011 |
Erythema multiforme photoinduced by paroxetine and herpes simplex virus.
Topics: Duloxetine Hydrochloride; Erythema Multiforme; Female; Herpes Simplex; Humans; Middle Aged; Paroxetine; Photosensitivity Disorders; Selective Serotonin Reuptake Inhibitors; Simplexvirus; Thiophenes | 2011 |
Association of catechol-O-methyltransferase variants with duloxetine response in major depressive disorder.
Topics: Adult; Antidepressive Agents; Catechol O-Methyltransferase; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Genome-Wide Association Study; Humans; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales; Sex Factors; Thiophenes | 2011 |
Medication dosing patterns associated with duloxetine and pregabalin among patients with fibromyalgia.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Algorithms; Analgesics; Comorbidity; Databases, Factual; Dose-Response Relationship, Drug; Drug Costs; Duloxetine Hydrochloride; Female; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Male; Medication Adherence; Middle Aged; Practice Patterns, Physicians'; Pregabalin; Retrospective Studies; Thiophenes; Young Adult | 2011 |
Electroretinographic assessment in major depressed patients receiving duloxetine: might differences between responders and non-responders indicate a differential biological background?
Topics: Adult; Antidepressive Agents; Case-Control Studies; Depression; Depressive Disorder; Depressive Disorder, Major; Dopamine; Duloxetine Hydrochloride; Electroretinography; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Sample Size; Thiophenes; Treatment Outcome | 2011 |
Reversible time-dependent inhibition of cytochrome P450 enzymes by duloxetine and inertness of its thiophene ring towards bioactivation.
Topics: Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Duloxetine Hydrochloride; Glutathione; Humans; Liver; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors | 2011 |
Effects of milnacipran, duloxetine and indomethacin, in polyarthritic rats using the Randall-Selitto model.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Indomethacin; Male; Milnacipran; Rats; Rats, Wistar; Thiophenes | 2011 |
Safety of electroconvulsive therapy-duloxetine combination.
Topics: Antidepressive Agents; Antipsychotic Agents; Combined Modality Therapy; Depressive Disorder, Major; Dibenzothiazepines; Duloxetine Hydrochloride; Electroconvulsive Therapy; Female; Humans; Male; Middle Aged; Quetiapine Fumarate; Suicidal Ideation; Thiophenes; Treatment Outcome | 2011 |
Galactorrhea during duloxetine treatment: a case report.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Duloxetine Hydrochloride; Female; Galactorrhea; Humans; Psychometrics; Thiophenes | 2011 |
Effects of baseline depression severity on remission rates with duloxetine and placebo in anxious and nonanxious patients with major depression.
Topics: Adult; Antidepressive Agents; Anxiety Disorders; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Logistic Models; Male; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Severity of Illness Index; Thiophenes; Treatment Outcome | 2011 |
Trajectory analysis of healthcare costs for patients with major depressive disorder treated with high doses of duloxetine.
Topics: Adolescent; Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Follow-Up Studies; Health Care Costs; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Regression Analysis; Retrospective Studies; Thiophenes; United States; Young Adult | 2011 |
Predictors of pain medication selection among patients diagnosed with fibromyalgia.
Topics: Adult; Analgesics; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Cohort Studies; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Pain; Predictive Value of Tests; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2012 |
Duloxetine's effects in resting functional magnetic resonance imaging of first-episode, drug-naive major depressive disorder with panic disorder patients.
Topics: Adolescent; Adult; Antidepressive Agents; Brain; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Magnetic Resonance Imaging; Male; Panic Disorder; Rest; Thiophenes | 2011 |
Predictors of duloxetine versus other treatments among veterans with diabetic peripheral neuropathic pain: a retrospective study.
Topics: Aged; Analgesics; Antidepressive Agents; Cohort Studies; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Predictive Value of Tests; Retrospective Studies; Thiophenes; Veterans | 2012 |
Comparative effectiveness in pain-related outcomes and health care utilizations between veterans with major depressive disorder treated with duloxetine and other antidepressants: a retrospective propensity score-matched comparison.
Topics: Adolescent; Adult; Aged; Analgesics; Antidepressive Agents; Chronic Pain; Cohort Studies; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain Measurement; Retrospective Studies; Thiophenes; Veterans; Young Adult | 2012 |
Colleague interactions and new drug prescribing behavior: the case of the initial prescription of antidepressants in Taiwanese medical centers.
Topics: Adult; Antidepressive Agents; Depression; Duloxetine Hydrochloride; Female; Humans; Interprofessional Relations; Interviews as Topic; Male; Middle Aged; Practice Patterns, Physicians'; Prescription Drugs; Proportional Hazards Models; Psychiatry; Taiwan; Thiophenes; Young Adult | 2011 |
[Because depression also hurts: duloxetine can help patients return to vitality].
Topics: Antidepressive Agents; Depressive Disorder; Duloxetine Hydrochloride; Humans; Pain; Pain Measurement; Quality of Life; Somatoform Disorders; Thiophenes | 2011 |
[Interview with Dr. Heike-Ariane Washeim, Zirndorf, and Dr. Heiner Buschmann, Übach-Palenberg (interview by Abdol A. Ameri)].
Topics: Antidepressive Agents; Depressive Disorder; Duloxetine Hydrochloride; General Practice; Humans; Somatoform Disorders; Thiophenes | 2011 |
Clinical comorbidities, treatment patterns, and healthcare costs among patients with fibromyalgia newly prescribed pregabalin or duloxetine in usual care.
Topics: Adolescent; Adult; Aged; Analgesics; Comorbidity; Databases, Factual; Drug Therapy; Duloxetine Hydrochloride; Female; Fibromyalgia; gamma-Aminobutyric Acid; Health Expenditures; Humans; Male; Middle Aged; Pregabalin; Retrospective Studies; Thiophenes; United States; Young Adult | 2012 |
Augmentative effects of fluvoxamine on duloxetine plasma levels in depressed patients.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Depressive Disorder; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Fluvoxamine; Humans; International Classification of Diseases; Male; Middle Aged; Retrospective Studies; Thiophenes | 2011 |
Partial status epilepticus after electroconvulsive therapy and medical treatment with bupropion.
Topics: Adrenergic Uptake Inhibitors; Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Bupropion; Depressive Disorder, Major; Duloxetine Hydrochloride; Electroconvulsive Therapy; Electroencephalography; Humans; Male; Seizures; Status Epilepticus; Thiophenes | 2011 |
Applying medicinal chemistry transformations and multiparameter optimization to guide the search for high-quality leads and candidates.
Topics: Algorithms; Chemistry, Pharmaceutical; Computational Biology; Computer Simulation; Drug Design; Drug Discovery; Duloxetine Hydrochloride; Humans; Quantitative Structure-Activity Relationship; Research Design; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Software; Thiophenes | 2011 |
Early discontinuation and suboptimal dosing of duloxetine treatment in patients with major depressive disorder: analysis from a US third-party payer perspective.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Insurance, Health, Reimbursement; Logistic Models; Male; Middle Aged; Thiophenes; United States; Withholding Treatment; Young Adult | 2012 |
Duloxetine in the acute and continuation treatment of major depressive disorder.
Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Thiophenes | 2011 |
Dosing patterns for duloxetine and predictors of high-dose prescriptions in patients with major depressive disorder: analysis from a United States third-party payer perspective.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Multivariate Analysis; Thiophenes; United States | 2011 |
Persistent genital arousal disorder: successful treatment with duloxetine and pregabalin in two cases.
Topics: Adult; Anticonvulsants; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sexual Dysfunction, Physiological; Thiophenes; Treatment Outcome | 2012 |
Polymorphism and a metastable solvate of duloxetine hydrochloride.
Topics: Acetone; Antidepressive Agents; Duloxetine Hydrochloride; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Solvents; Thiophenes; X-Ray Diffraction | 2011 |
Economic evaluation of duloxetine as a first-line treatment for painful diabetic peripheral neuropathy in Mexico.
Topics: Amines; Analgesics; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Dopamine Uptake Inhibitors; Drug Costs; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Mexico; Pregabalin; Thiophenes | 2012 |
Does pain improve earlier than mood in depressed patients with painful physical symptoms treated with duloxetine?
Topics: Adult; Affect; Antidepressive Agents; Chronic Pain; Depressive Disorder; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain Measurement; Prospective Studies; Surveys and Questionnaires; Thiophenes; Time Factors | 2012 |
Frequency of treatment-emergent sexual dysfunction and treatment effectiveness during SSRI or duloxetine therapy: 8-week data from a 6-month observational study.
Topics: Adrenergic Uptake Inhibitors; Adult; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Quality of Life; Selective Serotonin Reuptake Inhibitors; Sexual Dysfunctions, Psychological; Thiophenes | 2011 |
Treatment-emergent sexual dysfunction with SSRIs and duloxetine: effectiveness and functional outcomes over a 6-month observational period.
Topics: Adrenergic Uptake Inhibitors; Adult; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Prospective Studies; Quality of Life; Selective Serotonin Reuptake Inhibitors; Sexual Dysfunctions, Psychological; Thiophenes | 2011 |
Time course of improvement of different symptom clusters in patients with major depression and pain treated with duloxetine or placebo.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Multicenter Studies as Topic; Pain; Pain Measurement; Placebos; Randomized Controlled Trials as Topic; Retrospective Studies; Severity of Illness Index; Thiophenes; Time Factors; Treatment Outcome | 2012 |
Frontal regional homogeneity increased and temporal regional homogeneity decreased after remission of first-episode drug-naïve major depressive disorder with panic disorder patients under duloxetine therapy for 6 weeks.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Frontal Lobe; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Panic Disorder; Remission Induction; Temporal Lobe; Thiophenes | 2012 |
Takotsubo cardiomyopathy associated with titration of duloxetine.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Coronary Angiography; Duloxetine Hydrochloride; Electrocardiography; Female; Humans; Middle Aged; Recovery of Function; Selective Serotonin Reuptake Inhibitors; Stroke Volume; Takotsubo Cardiomyopathy; Thiophenes; Treatment Outcome; Ventricular Function, Left | 2011 |
Inhibition of G protein-activated inwardly rectifying K+ channels by different classes of antidepressants.
Topics: Amoxapine; Animals; Antidepressive Agents; Depression; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Ethanol; Female; GTP-Binding Proteins; Humans; Mice; Oocytes; Potassium Channels; RNA, Messenger; Sertraline; Thiophenes; Xenopus laevis | 2011 |
Duloxetine HCl lipid nanoparticles: preparation, characterization, and dosage form design.
Topics: Animals; Antidepressive Agents; Depression; Dosage Forms; Drug Design; Duloxetine Hydrochloride; Lipids; Male; Mice; Nanoparticles; Particle Size; Thiophenes; X-Ray Diffraction | 2012 |
Efficacy, safety and tolerability of duloxetine in idiopathic trigeminal neuralgia.
Topics: Adult; Aged; Aged, 80 and over; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Selective Serotonin Reuptake Inhibitors; Thiophenes; Trigeminal Neuralgia | 2011 |
Gap junction dysfunction in the prefrontal cortex induces depressive-like behaviors in rats.
Topics: Analysis of Variance; Animals; Carbenoxolone; Connexin 43; Disease Models, Animal; Duloxetine Hydrochloride; Electroshock; Exploratory Behavior; Fluoxetine; Food Deprivation; Food Preferences; Gap Junctions; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hormone Antagonists; Inhibition, Psychological; Isoquinolines; Male; Microscopy, Electron, Transmission; Mifepristone; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Restraint, Physical; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Social Isolation; Stress, Psychological; Sucrose; Sweetening Agents; Swimming; Thiophenes | 2012 |
Treatment with duloxetine in adults and the incidence of cardiovascular events.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cardiovascular Diseases; Case-Control Studies; Cause of Death; Cohort Studies; Cross-Sectional Studies; Cyclohexanols; Depressive Disorder; Duloxetine Hydrochloride; Electrocardiography; Female; Follow-Up Studies; Humans; Insurance Claim Review; Male; Propensity Score; Risk Factors; Selective Serotonin Reuptake Inhibitors; Thiophenes; United States; Venlafaxine Hydrochloride; Young Adult | 2012 |
Prediction of human serotonin and norepinephrine transporter occupancy of duloxetine by pharmacokinetic/pharmacodynamic modeling in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Male; Models, Neurological; Norepinephrine Plasma Membrane Transport Proteins; Predictive Value of Tests; Protein Binding; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Spinal Cord; Thiophenes | 2012 |
Pharmacogenetic investigation of response to duloxetine treatment in generalized anxiety disorder.
Topics: Adult; Anxiety Disorders; Biomarkers, Pharmacological; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Genetic Association Studies; Humans; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales; Receptors, Corticotropin-Releasing Hormone; Thiophenes | 2013 |
Selective serotonin reuptake inhibitors, venlafaxine and duloxetine are associated with in hospital morbidity but not bleeding or late mortality after coronary artery bypass graft surgery.
Topics: Aged; Aged, 80 and over; Australia; Coronary Artery Bypass; Coronary Artery Disease; Cyclohexanols; Depression; Duloxetine Hydrochloride; Female; Follow-Up Studies; Hospital Mortality; Humans; Kidney Diseases; Male; Middle Aged; Postoperative Hemorrhage; Proportional Hazards Models; Renal Dialysis; Respiration, Artificial; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Venlafaxine Hydrochloride | 2012 |
Exploratory translational modeling approach in drug development to predict human brain pharmacokinetics and pharmacologically relevant clinical doses.
Topics: Animals; Atomoxetine Hydrochloride; Biomarkers; Brain; Clinical Medicine; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Duloxetine Hydrochloride; Extracellular Fluid; Humans; Male; Microdialysis; Models, Biological; Predictive Value of Tests; Propylamines; Rats; Rats, Sprague-Dawley; Species Specificity; Thiophenes | 2012 |
Agomelatine-induced akathisia with concomitant duloxetine medication: a case report.
Topics: Acetamides; Adult; Akathisia, Drug-Induced; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Hypnotics and Sedatives; Thiophenes | 2012 |
Generalized tonic-clonic seizure secondary to duloxetine poisoning: a short report with favorable out come.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Electroencephalography; Humans; Male; Status Epilepticus; Thiophenes | 2012 |
Peripheral nerve toxic effects of nitrofurantoin.
Topics: Amines; Analgesics; Anti-Infective Agents, Urinary; Biopsy; Cyclohexanecarboxylic Acids; Cystitis, Interstitial; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Nerve Fibers; Neurologic Examination; Nitrofurantoin; Paresthesia; Perineum; Peripheral Nervous System Diseases; Psoriasis; Skin; Thiophenes; Treatment Outcome; Urinary Tract Infections | 2012 |
Dosing pattern comparison between duloxetine and pregabalin among patients with diabetic peripheral neuropathic pain.
Topics: Analgesics; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Practice Patterns, Physicians'; Pregabalin; Thiophenes | 2012 |
Assessing carrageenan-induced locomotor activity impairment in rats: comparison with evoked endpoint of acute inflammatory pain.
Topics: Acute Pain; Adrenergic Uptake Inhibitors; Amines; Amphetamine; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Carrageenan; Central Nervous System Stimulants; Cyclohexanecarboxylic Acids; Diclofenac; Disease Models, Animal; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Ibuprofen; Lameness, Animal; Male; Morphine; Motor Activity; Neuritis; Rats; Rats, Sprague-Dawley; Thiophenes | 2012 |
Acute massive pulmonary thromboembolism due to acute intoxication by duloxetine: a case report.
Topics: Acute Disease; Aged; Antidepressive Agents; Blood Pressure; Depressive Disorder; Duloxetine Hydrochloride; Fatal Outcome; Female; Heart Arrest; Heart Rate; Humans; Pulmonary Embolism; Thiophenes | 2012 |
Delirium associated with duloxetine in a depressed patient with Alzheimer's dementia.
Topics: Aged, 80 and over; Alzheimer Disease; Antidepressive Agents; Delirium; Depressive Disorder; Duloxetine Hydrochloride; Female; Humans; Thiophenes | 2012 |
The combined predictive capacity of rat models of algogen-induced and neuropathic hypersensitivity to clinically used analgesics varies with nociceptive endpoint and consideration of locomotor function.
Topics: Amines; Analgesics; Animals; Capsaicin; Cyclohexanecarboxylic Acids; Disease Models, Animal; Duloxetine Hydrochloride; Exploratory Behavior; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Locomotion; Male; Morphine; Neuralgia; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Thiophenes | 2012 |
Healthcare utilization among patients with depression before and after initiating duloxetine in the United Kingdom.
Topics: Adult; Aged; Analgesics; Antidepressive Agents; Databases, Factual; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Health Services Needs and Demand; Hospitalization; Humans; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Thiophenes; United Kingdom | 2012 |
The efficacy of morphine, pregabalin, gabapentin, and duloxetine on mechanical allodynia is different from that on neuroma pain in the rat neuropathic pain model.
Topics: Administration, Oral; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Morphine; Neuralgia; Neuroma; Pain Measurement; Pain Threshold; Pregabalin; Rats; Rats, Sprague-Dawley; Thiophenes; Time Factors | 2012 |
Evaluation of patient-rated stiffness associated with fibromyalgia: a post-hoc analysis of 4 pooled, randomized clinical trials of duloxetine.
Topics: Double-Blind Method; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Male; Middle Aged; Placebos; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2012 |
Antidepressants and the relief of osteoarthritic pain - findings from a study examining adjunctive duloxetine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Chronic Pain; Drug Combinations; Duloxetine Hydrochloride; Humans; Musculoskeletal Pain; Osteoarthritis; Thiophenes; Treatment Outcome | 2012 |
Etodolac, a cyclooxygenase-2 inhibitor, attenuates paclitaxel-induced peripheral neuropathy in a mouse model of mechanical allodynia.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Disease Models, Animal; Drug Interactions; Duloxetine Hydrochloride; Etodolac; gamma-Aminobutyric Acid; Hyperalgesia; Male; Mexiletine; Mice; Paclitaxel; Peripheral Nervous System Diseases; Pregabalin; Thiophenes; Tissue Distribution | 2012 |
Concise enantioselective synthesis of duloxetine via direct catalytic asymmetric aldol reaction of thioamide.
Topics: Catalysis; Crystallization; Duloxetine Hydrochloride; Ligands; Molecular Structure; Stereoisomerism; Thioamides; Thiophenes | 2012 |
A cost-utility analysis of pregabalin versus duloxetine for the treatment of painful diabetic neuropathy.
Topics: Analgesics; Antidepressive Agents; Clinical Trials as Topic; Cost-Benefit Analysis; Decision Trees; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Approval; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Humans; Models, Economic; Pregabalin; Quality-Adjusted Life Years; Thiophenes; United States; United States Food and Drug Administration | 2012 |
Determination and validation of duloxetine hydrochloride in capsules by HPLC with pre-column derivatization and fluorescence detection.
Topics: Antidepressive Agents; Capsules; Chromatography, High Pressure Liquid; Duloxetine Hydrochloride; Spectrometry, Fluorescence; Thiophenes | 2012 |
A simple HPLC method for the simultaneous determination of two selective serotonin reuptake inhibitors and two serotonin-norepinephrine reuptake inhibitors in hair, nail clippings, and cerebrospinal fluid.
Topics: Adrenergic Uptake Inhibitors; Biological Transport; Cerebrospinal Fluid; Chromatography, High Pressure Liquid; Cyclohexanols; Duloxetine Hydrochloride; Fluoxetine; Hair; Humans; Nails; Norepinephrine; Paroxetine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Venlafaxine Hydrochloride | 2012 |
A case of serotonin syndrome precipitated by fentanyl and ondansetron in a patient receiving paroxetine, duloxetine, and bupropion.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Bupropion; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Fentanyl; Humans; Mastectomy; Ondansetron; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Thiophenes | 2012 |
Fast versus slow onset of depressive episodes: a clinical criterion for subtyping patients with major depression.
Topics: Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Life Change Events; Male; Middle Aged; Suicide, Attempted; Thiophenes; Time Factors | 2013 |
Differential BDNF responses of triple versus dual reuptake inhibition in neuronal and astrocytoma cells as well as in rat hippocampus and prefrontal cortex.
Topics: Animals; Antidepressive Agents; Astrocytes; Astrocytoma; Aza Compounds; Brain Neoplasms; Brain-Derived Neurotrophic Factor; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Depressive Disorder; Duloxetine Hydrochloride; Hippocampus; Male; Mice; Neurons; Neurotransmitter Uptake Inhibitors; Prefrontal Cortex; Rats; Rats, Wistar; Thiophenes | 2012 |
Duloxetine blocks cloned Kv4.3 potassium channels.
Topics: Animals; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Patch-Clamp Techniques; Potassium Channel Blockers; Shal Potassium Channels; Thiophenes | 2012 |
Study of emotional and cognitive impairments in mononeuropathic rats: effect of duloxetine and gabapentin.
Topics: Affective Symptoms; Amines; Analgesics; Animals; Antidepressive Agents; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Duloxetine Hydrochloride; Emotions; Gabapentin; gamma-Aminobutyric Acid; Male; Neuralgia; Rats; Rats, Sprague-Dawley; Thiophenes; Treatment Outcome | 2012 |
Stress-induced changes of hippocampal NMDA receptors: modulation by duloxetine treatment.
Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Duloxetine Hydrochloride; Gene Expression Regulation; Hippocampus; Male; Memory; Phosphorylation; Prefrontal Cortex; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spatial Behavior; Stress, Psychological; Thiophenes | 2012 |
Duloxetine use in chronic low back pain: treatment patterns and costs.
Topics: Adult; Comorbidity; Costs and Cost Analysis; Duloxetine Hydrochloride; Female; Humans; Insurance, Health; International Classification of Diseases; Low Back Pain; Male; Middle Aged; Orthopedic Procedures; Selective Serotonin Reuptake Inhibitors; Sick Leave; Thiophenes | 2012 |
Tolerability aspects in duloxetine-treated patients with depression: Should one use a lower starting dose in clinical practice?
Topics: Adult; Aged; Analgesics; Antidepressive Agents; Depression; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Tolerance; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Precision Medicine; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes | 2012 |
Duloxetine withdrawal syndrome in a newborn.
Topics: Adult; Duloxetine Hydrochloride; Female; Fetus; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Prenatal Exposure Delayed Effects; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome; Thiophenes | 2013 |
Antidepressant-like effects of 071031B, a novel serotonin and norepinephrine reuptake inhibitor.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzodioxoles; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Immobility Response, Tonic; Male; Mice; Molecular Structure; Motor Activity; Norepinephrine Plasma Membrane Transport Proteins; Rats; Selective Serotonin Reuptake Inhibitors; Synaptosomes; Thiophenes | 2013 |
Intranasal administration of nanostructured lipid carriers containing CNS acting drug: pharmacodynamic studies and estimation in blood and brain.
Topics: Administration, Intranasal; Animals; Antidepressive Agents; Brain; Duloxetine Hydrochloride; Female; Lipids; Male; Motor Activity; Nanostructures; Rats; Rats, Wistar; Statistics, Nonparametric; Swimming; Thiophenes | 2012 |
A general approach for sample size calculation for the three-arm 'gold standard' non-inferiority design.
Topics: Antidepressive Agents; Citalopram; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Likelihood Functions; Multiple Sclerosis, Relapsing-Remitting; Placebos; Poisson Distribution; Randomized Controlled Trials as Topic; Research Design; Sample Size; Therapeutic Equivalency; Thiophenes; Time Factors; Treatment Outcome | 2012 |
Acute hepatic failure involving duloxetine hydrochloride.
Topics: Antidepressive Agents; Duloxetine Hydrochloride; Female; Humans; Liver Failure, Acute; Middle Aged; Thiophenes | 2012 |
Evaluation of the anti-ulcerogenic activity of the antidepressants duloxetine, amitriptyline, fluoxetine and mirtazapine in different models of experimental gastric ulcer in rats.
Topics: Amitriptyline; Animals; Anti-Ulcer Agents; Antidepressive Agents; Disease Models, Animal; Duloxetine Hydrochloride; Fluoxetine; Immersion; Indomethacin; Male; Mianserin; Mirtazapine; Rats; Rats, Sprague-Dawley; Reserpine; Restraint, Physical; Stomach Ulcer; Stress, Psychological; Thiophenes; Water | 2012 |
Observational study on safety and tolerability of duloxetine in the treatment of female stress urinary incontinence in German routine practice.
Topics: Antidepressive Agents; Drug-Related Side Effects and Adverse Reactions; Duloxetine Hydrochloride; Female; Germany; Humans; Incidence; Middle Aged; Private Practice; Risk Factors; Thiophenes; Urinary Incontinence, Stress | 2013 |
Duloxetine-induced lymphocytic colitis.
Topics: Antidepressive Agents; Colitis, Lymphocytic; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Thiophenes | 2012 |
Literature based drug interaction prediction with clinical assessment using electronic medical records: novel myopathy associated drug interactions.
Topics: Alprazolam; Databases, Factual; Drug Interactions; Duloxetine Hydrochloride; Electronic Health Records; Humans; Indoles; Loratadine; Muscular Diseases; Promethazine; Simvastatin; Thiophenes | 2012 |
Characterization of nerve growth factor-induced mechanical and thermal hypersensitivity in rats.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Celecoxib; Cyclohexanecarboxylic Acids; Diclofenac; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Nerve Growth Factor; Pain Threshold; Physical Stimulation; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Sulfonamides; Sulfones; Thiophenes; TRPV Cation Channels | 2013 |
Serotonin syndrome in a patient with chronic pain polypharmacy.
Topics: Adult; Amitriptyline; Anti-Allergic Agents; Antidepressive Agents; Carisoprodol; Cetirizine; Chronic Pain; Duloxetine Hydrochloride; Female; Humans; Muscle Relaxants, Central; Narcotics; Polypharmacy; Serotonin Syndrome; Thiophenes; Tramadol | 2014 |
Duloxetine-associated tardive dyskinesia resolved with fluvoxamine: a case report.
Topics: Depressive Disorder; Duloxetine Hydrochloride; Dyskinesia, Drug-Induced; Female; Fluvoxamine; Humans; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome | 2012 |
Serotonin-norepinephrine reuptake inhibitor treatment for tinnitus and depression.
Topics: Adrenergic Uptake Inhibitors; Aged; Depressive Disorder, Major; Duloxetine Hydrochloride; Follow-Up Studies; Humans; Male; Selective Serotonin Reuptake Inhibitors; Thiophenes; Tinnitus; Treatment Outcome | 2012 |
Pharmacological validation of early and late phase of rat mono-iodoacetate model using the Tekscan system.
Topics: Alkylating Agents; Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Chronic Disease; Dexamethasone; Dinoprostone; Disease Models, Animal; Duloxetine Hydrochloride; Hindlimb; Iodoacetates; Male; Morphine; Muscle Fibers, Skeletal; Naproxen; Neurons, Afferent; Pain Measurement; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Restraint, Physical; Synovial Fluid; Thiophenes; Weight-Bearing | 2013 |
Might different cytokine trends in depressed patients receiving duloxetine indicate differential biological backgrounds.
Topics: Adult; Antidepressive Agents; Biomarkers; Case-Control Studies; Cytokines; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Interferon-gamma; Interleukin-10; Interleukin-12; Interleukin-1beta; Interleukin-2; Interleukin-4; Male; Middle Aged; Psychiatric Status Rating Scales; Thiophenes; Treatment Outcome; Tumor Necrosis Factor-alpha | 2013 |
The role of the NMDA receptors and l-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of duloxetine in the forced swimming test.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Duloxetine Hydrochloride; Female; Mice; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Swimming; Thiophenes | 2012 |
Increased anterior cingulate regional homogeneity after duloxetine therapy in first-episode, drug-naïve, major depressive disorder with panic disorder patients: a case series.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Duloxetine Hydrochloride; Female; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Oxygen; Panic Disorder; Thiophenes; Young Adult | 2012 |
Increases in amplitude of low-frequency fluctuations in left fronto-parietal area after duloxetine therapy in first-episode, drug-naïve, major depressive disorder with panic disorder patients.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Frontal Lobe; Functional Laterality; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Oxygen; Panic Disorder; Parietal Lobe; Thiophenes; Young Adult | 2012 |
Successful treatment by adding duloxetine to pregabalin for peripheral neuropathy induced by paclitaxel.
Topics: Duloxetine Hydrochloride; Humans; Paclitaxel; Peripheral Nervous System Diseases; Pregabalin; Quality of Life; Thiophenes | 2013 |
Synthesis of duloxetine intermediate (S)-3-Chloro-1-(2-thienyl)-1-propanol with liquid-core immobilized Candida pseudotropicalis 104.
Topics: Bioreactors; Buffers; Candida; Capsules; Cell Proliferation; Cells, Immobilized; Chitosan; Duloxetine Hydrochloride; Hydrogen-Ion Concentration; Membranes, Artificial; Molecular Weight; Oxidation-Reduction; Phosphates; Potassium Compounds; Propanols; Thiophenes | 2012 |
A case of severe hyponatremia induced by duloxetine and ziprasidone.
Topics: Antidepressive Agents; Antipsychotic Agents; Creatine Kinase; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Hyponatremia; Middle Aged; Piperazines; Thiazoles; Thiophenes | 2012 |
Development of microscopic colitis secondary to duloxetine.
Topics: Aged; Antidepressive Agents; Colitis, Microscopic; Depression; Duloxetine Hydrochloride; Female; Humans; Remission, Spontaneous; Thiophenes | 2013 |
Single-agent duloxetine ingestions.
Topics: Adult; Antidepressive Agents; Child; Dizziness; Duloxetine Hydrochloride; Eating; Female; Humans; Lethargy; Male; Middle Aged; Nausea; Poison Control Centers; Sleep Stages; Tachycardia; Thiophenes; Vomiting; Young Adult | 2013 |
Duloxetine and pregabalin for pain management in multiple rheumatic diseases associated with fibromyalgia.
Topics: Analgesics; Comorbidity; Duloxetine Hydrochloride; Female; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Middle Aged; Pregabalin; Rheumatic Diseases; Thiophenes | 2013 |
Rates of major malformations in infants following exposure to duloxetine during pregnancy: a preliminary report.
Topics: Abnormalities, Drug-Induced; Antidepressive Agents; Case-Control Studies; Cohort Studies; Depressive Disorder; Duloxetine Hydrochloride; Female; Humans; Infant, Newborn; Pregnancy; Pregnancy Trimesters; Prospective Studies; Sample Size; Thiophenes | 2012 |
Antidepressant use in underweight older adults.
Topics: Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents; Appetite; Body Mass Index; Body Weight; Depressive Disorder, Major; Duloxetine Hydrochloride; Hospitals, University; Humans; Inservice Training; Mianserin; Mirtazapine; Practice Patterns, Physicians'; Retrospective Studies; Thinness; Thiophenes | 2012 |
Interactive medical case. A patient found unresponsive.
Topics: Adolescent; Anorexia Nervosa; Antidepressive Agents; Antipsychotic Agents; Depressive Disorder, Major; Diagnosis, Differential; Dibenzothiazepines; Duloxetine Hydrochloride; Electrocardiography; Female; Humans; Hypokalemia; Quetiapine Fumarate; Suicide, Attempted; Thiophenes; Unconsciousness | 2012 |
Association of candidate gene polymorphisms with diastolic blood pressure change in patients treated with duloxetine.
Topics: Adrenergic Uptake Inhibitors; Blood Pressure; Catechol O-Methyltransferase; Depressive Disorder, Major; Diastole; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Norepinephrine Plasma Membrane Transport Proteins; Pain; Polymorphism, Single Nucleotide; Receptors, Adrenergic, beta-2; Receptors, Dopamine; Receptors, Serotonin; Thiophenes | 2013 |
Dispersive liquid-liquid microextraction based on solidification of floating organic droplets followed by high performance liquid chromatography for the determination of duloxetine in human plasma.
Topics: Antidepressive Agents; Calibration; Chemical Precipitation; Chromatography, High Pressure Liquid; Cold Temperature; Duloxetine Hydrochloride; Green Chemistry Technology; Half-Life; Humans; Hydrogen-Ion Concentration; Limit of Detection; Liquid Phase Microextraction; Neurotransmitter Uptake Inhibitors; Osmolar Concentration; Phase Transition; Protein Denaturation; Reproducibility of Results; Solvents; Spectrometry, Fluorescence; Tablets, Enteric-Coated; Thiophenes | 2013 |
Use of antidepressants for depression in patients with Parkinson's disease.
Topics: Antidepressive Agents; Depression; Duloxetine Hydrochloride; Humans; Parkinson Disease; Positron-Emission Tomography; Thiophenes | 2013 |
Antidepressant-selective gynecomastia.
Topics: Aged; Amlodipine; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Duloxetine Hydrochloride; Fluorobenzenes; Gynecomastia; Humans; Male; Pyrimidines; Rosuvastatin Calcium; Sertraline; Sulfonamides; Thiophenes | 2013 |
A retrospective review of isolated duloxetine-exposure cases.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; California; Databases, Factual; Drug Overdose; Duloxetine Hydrochloride; Electrocardiography; Emergency Medical Services; Female; Humans; Male; Middle Aged; Poison Control Centers; Pregnancy; Retrospective Studies; Suicide, Attempted; Thiophenes; Treatment Outcome; Young Adult | 2013 |
Pain treatment for patients with osteoarthritis and central sensitization.
Topics: Brain Mapping; Cognitive Behavioral Therapy; Duloxetine Hydrochloride; Exercise Therapy; Humans; Hyperalgesia; Magnetic Resonance Imaging; Neuralgia; Neuroglia; Nociception; Osteoarthritis; Pain Management; Physical Therapy Modalities; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2013 |
Collagenous colitis and ileitis under treatment with duloxetine.
Topics: Aged; Antidepressive Agents; Biopsy; Chronic Disease; Colitis, Collagenous; Colon; Colonoscopy; Depressive Disorder, Major; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Ileitis; Ileum; Recurrence; Thiophenes; Treatment Outcome; Withholding Treatment | 2012 |
Effectiveness and tolerability of duloxetine in 2 different ethnic samples: a prospective observational cohort study.
Topics: Adult; American Indian or Alaska Native; Antidepressive Agents; Cohort Studies; Depressive Disorder, Major; Duloxetine Hydrochloride; Ethnicity; Female; Humans; Male; Middle Aged; Prospective Studies; Spain; Thiophenes; Treatment Outcome; White People | 2013 |
Longitudinal analysis of healthcare costs: a case study of patients with major depressive disorder treated with duloxetine.
Topics: Adolescent; Adult; Age Factors; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Female; Health Expenditures; Humans; Insurance, Health; Longitudinal Studies; Male; Middle Aged; Residence Characteristics; Retrospective Studies; Sex Factors; Thiophenes; Young Adult | 2013 |
Duloxetine-induced life-threatening long QT syndrome.
Topics: Antidepressive Agents; Arrhythmia, Sinus; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Long QT Syndrome; Middle Aged; Thiophenes | 2013 |
[Is there a place for the physician's hopelesness in the treatment of depression?].
Topics: Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Chronic Disease; Depressive Disorder; Depressive Disorder, Treatment-Resistant; Drug Therapy, Combination; Duloxetine Hydrochloride; Humans; Male; Middle Aged; Physician's Role; Piperazines; Quinolones; Remission Induction; Risk Factors; Thiophenes; Treatment Outcome | 2013 |
Duloxetine and pregnancy outcomes: safety surveillance findings.
Topics: Abortion, Spontaneous; Adult; Adverse Drug Reaction Reporting Systems; Antidepressive Agents; Depressive Disorder, Major; Drug-Related Side Effects and Adverse Reactions; Duloxetine Hydrochloride; Female; Humans; Infant; Infant, Newborn; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Thiophenes; United States; United States Food and Drug Administration | 2013 |
Direct medical costs and medication compliance among fibromyalgia patients: duloxetine initiators vs. pregabalin initiators.
Topics: Adolescent; Adult; Cohort Studies; Databases, Factual; Duloxetine Hydrochloride; Female; Fibromyalgia; gamma-Aminobutyric Acid; Health Care Costs; Humans; Male; Medication Adherence; Middle Aged; Pregabalin; Retrospective Studies; Thiophenes; Young Adult | 2014 |
Levomilnacipran (F2695), a norepinephrine-preferring SNRI: profile in vitro and in models of depression and anxiety.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Cerebral Cortex; Cyclohexanols; Cyclopropanes; Depression; Dopamine; Duloxetine Hydrochloride; Humans; Male; Mice; Milnacipran; Motor Activity; Neurotransmitter Transport Proteins; Norepinephrine; Rats; Serotonin; Synaptosomes; Thiophenes; Venlafaxine Hydrochloride | 2013 |
Retraumatization eliciting the presentation of fibromyalgia.
Topics: Adult; Analgesics; Antidepressive Agents; Cannabinoids; Duloxetine Hydrochloride; Female; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Pregabalin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Stress, Psychological; Thiophenes; Uterine Rupture | 2013 |
Quantitative determination of duloxetine and its metabolite in rat plasma by HPLC-MS/MS.
Topics: Acetates; Animals; Chromatography, High Pressure Liquid; Drug Stability; Duloxetine Hydrochloride; Methanol; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Thiophenes | 2013 |
Chronic administration of duloxetine and mirtazapine downregulates proapoptotic proteins and upregulates neurotrophin gene expression in the hippocampus and cerebral cortex of mice.
Topics: Animals; Antidepressive Agents; Apoptosis Regulatory Proteins; Behavior, Animal; Cerebral Cortex; Down-Regulation; Duloxetine Hydrochloride; Female; Hippocampus; Mianserin; Mice; Mirtazapine; Nerve Growth Factors; Thiophenes; Up-Regulation | 2013 |
Conservative treatment options for women with stress urinary incontinence: clinical update.
Topics: Adrenergic Uptake Inhibitors; Behavior Therapy; Biofeedback, Psychology; Duloxetine Hydrochloride; Electric Stimulation Therapy; Exercise Therapy; Female; Humans; Pelvic Floor; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2013 |
Duloxetine reduces chemotherapy induced peripheral neuropathy.
Topics: Antidepressive Agents; Antineoplastic Agents; Duloxetine Hydrochloride; Humans; Pain; Peripheral Nervous System Diseases; Thiophenes | 2013 |
Severe urinary retention requiring urinary catheterization associated with combined treatment of depression with duloxetine and quetiapine.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Depressive Disorder; Dibenzothiazepines; Drug Therapy, Combination; Duloxetine Hydrochloride; Humans; Male; Quetiapine Fumarate; Thiophenes; Urinary Catheterization; Urinary Retention | 2013 |
Cardiac syncope due to pain: report of a case responsive to duloxetine treatment.
Topics: Adult; Analgesics; Duloxetine Hydrochloride; Female; Humans; Pain; Syncope; Thiophenes; Treatment Outcome | 2013 |
Pharmacokinetic analysis of two different doses of duloxetine following oral administration in dogs.
Topics: Administration, Oral; Animals; Dogs; Duloxetine Hydrochloride; Models, Biological; Thiophenes | 2013 |
Cost-utility analysis of duloxetine in osteoarthritis: a US private payer perspective.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Cost-Benefit Analysis; Duloxetine Hydrochloride; Female; Humans; Male; Markov Chains; Middle Aged; Models, Economic; Osteoarthritis; Prescription Fees; Thiophenes; United States | 2013 |
Duloxetine and hypothermia: possible summation of effect in QTc interval prolongation.
Topics: Antidepressive Agents; Duloxetine Hydrochloride; Female; Humans; Hypothermia; Long QT Syndrome; Middle Aged; Thiophenes | 2013 |
Acute and subacute effects of the selective serotonin-noradrenaline reuptake inhibitor duloxetine on cardiac hERG channels.
Topics: Adrenergic Uptake Inhibitors; Animals; Duloxetine Hydrochloride; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Heart; HEK293 Cells; Humans; Oocytes; Selective Serotonin Reuptake Inhibitors; Thiophenes; Xenopus laevis | 2013 |
Postictal ventricular tachycardia after electroconvulsive therapy treatment associated with a lithium-duloxetine combination.
Topics: Androstanols; Anesthesia; Antidepressive Agents; Antimanic Agents; Anxiety; Bipolar Disorder; Duloxetine Hydrochloride; Electrocardiography; Electroconvulsive Therapy; Female; Humans; Lithium Carbonate; Middle Aged; Neuromuscular Depolarizing Agents; Neuromuscular Nondepolarizing Agents; Psychomotor Agitation; Recurrence; Rocuronium; Succinylcholine; Tachycardia, Ventricular; Thiophenes | 2013 |
[Sweating under polypharmacy with tramadol, amitriptyline and duloxetine?].
Topics: Amitriptyline; Analgesics, Opioid; Antidepressive Agents; Antidepressive Agents, Tricyclic; Duloxetine Hydrochloride; Humans; Polypharmacy; Serotonin Syndrome; Sweating; Thiophenes; Tramadol | 2013 |
Severe postoperative hyperthermic syndrome after addition of tilidine/naloxone to duloxetine therapy.
Topics: Aged; Analgesics; Brain; Drug Interactions; Duloxetine Hydrochloride; Female; Fever; Humans; Magnetic Resonance Imaging; Naloxone; Narcotic Antagonists; Narcotics; Neuroimaging; Postoperative Complications; Thiophenes; Tilidine | 2013 |
Add-on therapy: when two are not better than one.
Topics: Diabetic Neuropathies; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Male; Pain; Pregabalin; Thiophenes | 2013 |
Three-arm noninferiority trials with a prespecified margin for inference of the difference in the proportions of binary endpoints.
Topics: Antidepressive Agents; Confidence Intervals; Data Interpretation, Statistical; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Endpoint Determination; Humans; Models, Statistical; Monte Carlo Method; Placebos; Randomized Controlled Trials as Topic; Research Design; Sample Size; Thiophenes; Treatment Outcome | 2013 |
Clinical characteristics and medication uses among fibromyalgia patients newly prescribed amitriptyline, duloxetine, gabapentin, or pregabalin.
Topics: Amines; Amitriptyline; Analgesics; Anti-Anxiety Agents; Antidepressive Agents; Cyclohexanecarboxylic Acids; Disease Progression; Duloxetine Hydrochloride; Female; Fibromyalgia; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Pregabalin; Prescription Drugs; Retrospective Studies; Thiophenes; Treatment Outcome | 2013 |
Intranasal infusion of nanostructured lipid carriers (NLC) containing CNS acting drug and estimation in brain and blood.
Topics: Absorption; Administration, Intranasal; Animals; Antidepressive Agents; Brain; Duloxetine Hydrochloride; Female; Lipids; Male; Nanostructures; Nasal Mucosa; Rats; Rats, Wistar; Thiophenes | 2013 |
VEGF plasma level variations in duloxetine-treated patients with major depression.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes; Vascular Endothelial Growth Factor A | 2013 |
Infant health and neurodevelopmental outcomes following prenatal exposure to duloxetine.
Topics: Adult; Antidepressive Agents; Brain; Child Development; Duloxetine Hydrochloride; Female; Fetus; Humans; Infant; Pregnancy; Thiophenes | 2013 |
Prescribing patterns and safety monitoring of duloxetine using the Danish Register of Medicinal Product Statistics as a source.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Child; Child, Preschool; Denmark; Depression; Drug Monitoring; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Practice Patterns, Physicians'; Registries; Retrospective Studies; Thiophenes; Young Adult | 2013 |
[Duloxetine for chronic pain management: pharmacology and clinical use].
Topics: Adrenergic Uptake Inhibitors; Chronic Pain; Depression; Depressive Disorder; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Thiophenes | 2013 |
Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability.
Topics: Amitriptyline; Animals; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Capillary Permeability; Dogs; Duloxetine Hydrochloride; Fluoxetine; Humans; Imipramine; Madin Darby Canine Kidney Cells; Mianserin; Mirtazapine; Thiophenes; Transfection | 2013 |
Local control for identifying subgroups of interest in observational research: persistence of treatment for major depressive disorder.
Topics: Adolescent; Adult; Age Factors; Caregivers; Cluster Analysis; Cyclohexanols; Data Mining; Decision Making; Delayed-Action Preparations; Depressive Disorder, Major; Drug Costs; Duloxetine Hydrochloride; Female; Health Education; Humans; Insurance Claim Reporting; Male; Middle Aged; Observational Studies as Topic; Outcome and Process Assessment, Health Care; Statistics as Topic; Statistics, Nonparametric; Thiophenes; Venlafaxine Hydrochloride; Young Adult | 2013 |
Opioid and noradrenergic contributions of tapentadol in experimental neuropathic pain.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Duloxetine Hydrochloride; Male; Morphine; Neuralgia; Norepinephrine; Pain Measurement; Phenols; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Nerves; Tapentadol; Thiophenes | 2014 |
Prenatal antidepressant exposure and risk of spontaneous abortion - a population-based study.
Topics: Abortion, Spontaneous; Adult; Antidepressive Agents; Cyclohexanols; Depression; Duloxetine Hydrochloride; Female; Humans; Maternal-Fetal Exchange; Mianserin; Mirtazapine; Pregnancy; Risk; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Thiophenes; Venlafaxine Hydrochloride; Young Adult | 2013 |
Duloxetine prophylaxis for episodic migraine in persons without depression: a prospective study.
Topics: Adult; Antidepressive Agents; Depression; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Migraine Disorders; Pilot Projects; Prospective Studies; Thiophenes; Young Adult | 2013 |
Stability of the acetic acid-induced bladder irritation model in alpha chloralose-anesthetized female cats.
Topics: Acetic Acid; Adrenergic Uptake Inhibitors; Anesthesia; Animals; Blood Pressure; Cats; Chloralose; Disease Models, Animal; Duloxetine Hydrochloride; Electromyography; Female; Heart Rate; Humans; Hypnotics and Sedatives; Muscle Contraction; Respiration; Thiophenes; Time Factors; Urethra; Urinary Bladder; Urinary Bladder Diseases; Urination | 2013 |
Duloxetine-related galactorrhea and restless legs syndrome: a case report.
Topics: Antidepressive Agents; Depression; Duloxetine Hydrochloride; Female; Galactorrhea; Humans; Middle Aged; Restless Legs Syndrome; Thiophenes | 2013 |
Possible drug-drug interaction between adalimumab and duloxetine and/or pregabalin in a psoriasis patient.
Topics: Adalimumab; Analgesics; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Antidepressive Agents; Biological Products; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Drug Interactions; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Pregabalin; Psoriasis; Thiophenes; Young Adult | 2013 |
Pharmacogenetic workup of perioperative serotonin syndrome.
Topics: Anesthesia, General; Cytochrome P-450 CYP2D6; Drug Interactions; Duloxetine Hydrochloride; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Postoperative Complications; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Thiophenes | 2013 |
Relative contributions of norepinephrine and serotonin transporters to antinociceptive synergy between monoamine reuptake inhibitors and morphine in the rat formalin model.
Topics: Analgesia; Animals; Atomoxetine Hydrochloride; Biogenic Monoamines; Chromatography, Liquid; Drug Synergism; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Morphine; Morpholines; Neurotransmitter Uptake Inhibitors; Nociceptive Pain; Norepinephrine Plasma Membrane Transport Proteins; Ondansetron; Propylamines; Rats; Rotarod Performance Test; Serotonin Plasma Membrane Transport Proteins; Tandem Mass Spectrometry; Thiophenes | 2013 |
Dopamine-agonist responsive Parkinsonism in a patient with the SANDO syndrome caused by POLG mutation.
Topics: Benzothiazoles; DNA Mutational Analysis; DNA Polymerase gamma; DNA-Directed DNA Polymerase; Dopamine Agonists; Duloxetine Hydrochloride; Dysarthria; Female; Hereditary Sensory and Motor Neuropathy; Humans; Middle Aged; Mitochondria; Ophthalmoplegia; Parkinson Disease; Pramipexole; Thiophenes; Tomography, Emission-Computed, Single-Photon | 2013 |
Synergistic analgesia of duloxetine and celecoxib in the mouse formalin test: a combination analysis.
Topics: Analgesics; Analysis of Variance; Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Duloxetine Hydrochloride; Formaldehyde; Hindlimb; Injections, Intraperitoneal; Male; Mice, Inbred C57BL; Motor Activity; Nociceptive Pain; Pain Measurement; Pyrazoles; Sulfonamides; Thiophenes | 2013 |
Commentary on: Opioid and noradrenergic contributions of tapentadol in experimental neuropathic pain.
Topics: Analgesics, Opioid; Animals; Duloxetine Hydrochloride; Male; Morphine; Neuralgia; Phenols; Spinal Nerves; Tapentadol; Thiophenes | 2014 |
Inhibition of bladder overactivity by duloxetine in combination with foot stimulation or WAY-100635 treatment in cats.
Topics: Animals; Cats; Combined Modality Therapy; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Duloxetine Hydrochloride; Electric Stimulation Therapy; Female; Foot; Male; Piperazines; Pyridines; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Thiophenes; Urinary Bladder; Urinary Bladder, Overactive | 2013 |
[Treatment of the urethral sphincter insufficiency].
Topics: Acrylic Resins; Biocompatible Materials; Biofeedback, Psychology; Catheterization; Collagen; Duloxetine Hydrochloride; Electric Stimulation Therapy; Female; Hormone Replacement Therapy; Humans; Hydrogels; Injections; Male; Medical History Taking; Physical Examination; Selective Serotonin Reuptake Inhibitors; Stem Cell Transplantation; Suburethral Slings; Thiophenes; Urethra; Urethral Stricture; Urinary Incontinence, Stress; Urinary Sphincter, Artificial; Urodynamics | 2013 |
Socioeconomic deprivation independently predicts symptomatic painful diabetic neuropathy in type 1 diabetes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amitriptyline; Analgesics; Biomarkers; Body Mass Index; Chi-Square Distribution; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Duloxetine Hydrochloride; England; Female; Glycated Hemoglobin; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Poverty; Prevalence; Risk Assessment; Risk Factors; Severity of Illness Index; Thiophenes; Young Adult | 2014 |
AS1069562, the (+)-isomer of indeloxazine, but not duloxetine has a curative-like analgesic effect in a rat model of streptozotocin-induced diabetic neuropathy.
Topics: Analgesics; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibroblast Growth Factor 2; Ganglia, Spinal; Hyperalgesia; Insulin-Like Growth Factor I; Male; Morpholines; Neural Conduction; Neurotransmitter Uptake Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Cord; Streptozocin; Thiophenes; Time Factors | 2014 |
Duloxetine attenuated morphine withdrawal syndrome in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Dopamine Uptake Inhibitors; Duloxetine Hydrochloride; Injections, Intraperitoneal; Male; Morphine Dependence; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome; Thiophenes | 2014 |
Impaired noradrenaline homeostasis in rats with painful diabetic neuropathy as a target of duloxetine analgesia.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Duloxetine Hydrochloride; Male; Norepinephrine; Rats; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2013 |
Vortioxetine, but not escitalopram or duloxetine, reverses memory impairment induced by central 5-HT depletion in rats: evidence for direct 5-HT receptor modulation.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Citalopram; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Exploratory Behavior; Female; Hippocampus; Maze Learning; Memory Disorders; Phenylalanine; Piperazines; Protein Binding; Rats; Rats, Long-Evans; Recognition, Psychology; Selective Serotonin Reuptake Inhibitors; Serotonin; Sulfides; Thiophenes; Vortioxetine | 2014 |
Cost comparison of drug-drug and drug-condition interactions in patients with painful diabetic peripheral neuropathy treated with pregabalin versus duloxetine.
Topics: Aged; Analgesics; Cohort Studies; Databases, Factual; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Health Care Costs; Humans; Male; Middle Aged; Pregabalin; Retrospective Studies; Thiophenes; United States | 2013 |
Effectiveness of duloxetine compared with pregabalin and gabapentin in diabetic peripheral neuropathic pain: results from a German observational study.
Topics: Aged; Amines; Analgesics; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Germany; Health Surveys; Humans; Male; Middle Aged; Pain Measurement; Pregabalin; Prospective Studies; Thiophenes; Treatment Outcome | 2014 |
Duloxetine: withdrawal syndromes.
Topics: Duloxetine Hydrochloride; Humans; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome; Thiophenes | 2013 |
Can topical duloxetine be used for neuropathic pain?
Topics: Administration, Topical; Analgesia; Analgesics; Animals; Duloxetine Hydrochloride; Humans; Models, Theoretical; Neuralgia; Rats; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2014 |
AS1069562, the (+)-isomer of indeloxazine, exerts analgesic effects in a rat model of neuropathic pain with unique characteristics in spinal monoamine turnover.
Topics: Amitriptyline; Analgesics; Animals; Biogenic Monoamines; Dopamine; Dopamine Plasma Membrane Transport Proteins; Duloxetine Hydrochloride; Gastric Emptying; HEK293 Cells; Humans; Male; Morpholines; Motor Activity; Neuralgia; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Spinal Cord; Stereoisomerism; Thiophenes | 2014 |
Drugs for neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pregabalin; Thiophenes; Treatment Outcome | 2013 |
The prevalence of duloxetine in medico-legal death investigations in Victoria, Australia (2009-2012).
Topics: Adult; Aged; Antidepressive Agents; Australia; Cardiomegaly; Cause of Death; Chromatography, Liquid; Cohort Studies; Coronary Artery Disease; Coroners and Medical Examiners; Drug Interactions; Duloxetine Hydrochloride; Female; Forensic Toxicology; Humans; Male; Middle Aged; Pharmaceutical Preparations; Prevalence; Pulmonary Edema; Tandem Mass Spectrometry; Thiophenes | 2014 |
Copper(II)-catalyzed enantioselective hydrosilylation of halo-substituted alkyl aryl and heteroaryl ketones: asymmetric synthesis of (R)-fluoxetine and (S)-duloxetine.
Topics: Catalysis; Copper; Duloxetine Hydrochloride; Fluoxetine; Ketones; Molecular Conformation; Organometallic Compounds; Stereoisomerism; Thiophenes | 2014 |
Potential drug-drug and drug-condition interactions among fibromyalgia patients initiating pregabalin or duloxetine: prevalence and health care expenditure impact.
Topics: Adult; Analgesics; Cohort Studies; Drug Interactions; Duloxetine Hydrochloride; Female; Fibromyalgia; gamma-Aminobutyric Acid; Health Expenditures; Humans; Male; Middle Aged; Pregabalin; Prevalence; Retrospective Studies; Thiophenes | 2014 |
Impact of patient selection and study characteristics on signal detection in placebo-controlled trials with antidepressants.
Topics: Adult; Analysis of Variance; Antidepressive Agents; Databases, Factual; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Patient Selection; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Research Design; Signal Detection, Psychological; Thiophenes; Young Adult | 2014 |
Painful traumatic trigeminal neuropathy: an open study on the pharmacotherapeutic response to stepped treatment.
Topics: Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Baclofen; Carbamazepine; Clinical Protocols; Cohort Studies; Cyclohexanecarboxylic Acids; Drug Combinations; Duloxetine Hydrochloride; Female; Follow-Up Studies; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Medical Records; Middle Aged; Nortriptyline; Pain; Pain Measurement; Pregabalin; Prognosis; Prospective Studies; Thiophenes; Treatment Outcome; Trigeminal Nerve Injuries; Trigeminal Neuralgia | 2014 |
Duloxetine-induced pseudolymphoma with features of lymphocytic infiltration of Jessner-Kanof.
Topics: Analgesics; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Pseudolymphoma; Skin Diseases; Thiophenes | 2014 |
Long-term duloxetine withdrawal syndrome and management in a depressed patient.
Topics: Antidepressive Agents; Depression; Duloxetine Hydrochloride; Female; Humans; Substance Withdrawal Syndrome; Thiophenes | 2014 |
Assessment of thermal sensitivity in rats using the thermal place preference test: description and application in the study of oxaliplatin-induced acute thermal hypersensitivity and inflammatory pain models.
Topics: Analgesics; Analgesics, Opioid; Animals; Carrageenan; Cold Temperature; Conditioning, Psychological; Disease Models, Animal; Duloxetine Hydrochloride; Hot Temperature; Hyperalgesia; Male; Morphine; Organoplatinum Compounds; Oxaliplatin; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Space Perception; Temperature; Thiophenes | 2014 |
Duloxetine use in employees with low back pain: treatment patterns and direct and indirect costs.
Topics: Adolescent; Adult; Analgesics; Duloxetine Hydrochloride; Female; Health Care Costs; Humans; Low Back Pain; Male; Middle Aged; Occupational Health; Retrospective Studies; Thiophenes; Treatment Outcome; Young Adult | 2014 |
[Conservative treatment in male urinary incontinence].
Topics: Adrenergic Uptake Inhibitors; Duloxetine Hydrochloride; Electric Stimulation Therapy; Exercise Therapy; Humans; Male; Men's Health; Muscarinic Antagonists; Pelvic Floor; Prostatectomy; Thiophenes; Treatment Outcome; Urinary Incontinence, Stress | 2014 |
Response to antidepressant medications in late-life depression across the spectrum of cognitive functioning.
Topics: Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Aripiprazole; Citalopram; Cognitive Dysfunction; Cyclohexanols; Dementia; Depressive Disorder, Major; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Piperazines; Quinolones; Randomized Controlled Trials as Topic; Recurrence; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors; Venlafaxine Hydrochloride | 2014 |
Do predictive parameters exist for therapy with duloxetine in women with stress urinary incontinence?
Topics: Adolescent; Adult; Age Factors; Aged; Body Mass Index; Cholinergic Antagonists; Comorbidity; Drug Interactions; Duloxetine Hydrochloride; Europe; Female; Humans; Longitudinal Studies; Mexico; Middle Aged; Patient Selection; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Smoking; Thiophenes; Urinary Incontinence, Stress; Young Adult | 2014 |
Burning paresthesia related to duloxetine therapy.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Paresthesia; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2014 |
Duloxetine may enhance control of pain related to bladder trauma.
Topics: Analgesics; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Male; Pelvic Pain; Thiophenes; Treatment Outcome; Young Adult | 2014 |
Investigation on the enantioseparation of duloxetine by capillary electrophoresis, NMR, and mass spectrometry.
Topics: Antidepressive Agents; Cyclodextrins; Duloxetine Hydrochloride; Electrophoresis, Capillary; Magnetic Resonance Spectroscopy; Mass Spectrometry; Stereoisomerism; Thiophenes | 2014 |
Effects of duloxetine and WAY100635 on pudendal inhibition of bladder overactivity in cats.
Topics: Acetic Acid; Adrenergic Uptake Inhibitors; Animals; Cats; Dose-Response Relationship, Drug; Drug Therapy, Combination; Duloxetine Hydrochloride; Electric Stimulation; Female; Male; Piperazines; Pudendal Nerve; Pyridines; Serotonin; Serotonin Antagonists; Thiophenes; Urinary Bladder, Overactive | 2014 |
Agomelatine and duloxetine synergistically modulates apoptotic pathway by inhibiting oxidative stress triggered intracellular calcium entry in neuronal PC12 cells: role of TRPM2 and voltage-gated calcium channels.
Topics: Acetamides; Animals; Antidepressive Agents; Antioxidants; Apoptosis; Calcium; Calcium Channels; Caspase 3; Caspase 9; Drug Synergism; Duloxetine Hydrochloride; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Oxidative Stress; PC12 Cells; Rats; Thiophenes; TRPM Cation Channels | 2014 |
The analgesia effect of duloxetine on post-operative pain via intrathecal or intraperitoneal administration.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Duloxetine Hydrochloride; Hyperalgesia; Idazoxan; Injections, Intraperitoneal; Injections, Spinal; Ketanserin; Male; Microdialysis; Norepinephrine; Pain, Postoperative; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Spinal Cord; Thiophenes | 2014 |
Antinociceptive effects of AS1069562, the (+)-isomer of indeloxazine, on spinal hypersensitivity induced by intrathecal injection of prostaglandin in mice: comparison with duloxetine and amitriptyline.
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hyperalgesia; Injections, Spinal; Male; Mice, Inbred ICR; Morpholines; Neuralgia; Prostaglandins; Spinal Cord; Stereoisomerism; Thiophenes | 2014 |
Face-to-face comparison of the predictive validity of two models of neuropathic pain in the rat: analgesic activity of pregabalin, tramadol and duloxetine.
Topics: Analgesics; Animals; Cold Temperature; Disease Models, Animal; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Male; Neuralgia; Physical Stimulation; Pregabalin; Rats, Wistar; Sciatic Nerve; Thiophenes; Tramadol | 2014 |
ACP Journal Club. Review: In neuropathy, fibromyalgia, or chronic pain, duloxetine reduces pain but increases adverse events.
Topics: Analgesics; Chronic Pain; Diabetic Neuropathies; Duloxetine Hydrochloride; Fibromyalgia; Humans; Neuralgia; Thiophenes | 2014 |
[Anorexia nervosa in a female patient with diabetes mellitus type 1].
Topics: Anorexia Nervosa; Antidepressive Agents; Diabetes Mellitus, Type 1; Duloxetine Hydrochloride; Female; Humans; Thiophenes; Treatment Outcome; Young Adult | 2014 |
Amenorrhea associated with duloxetine: two case reports.
Topics: Adult; Amenorrhea; Antidepressive Agents; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Thiophenes | 2014 |
Handling missing data in a duloxetine population pharmacokinetic/pharmacodynamic model - imputation methods and selection models.
Topics: Analgesics; Computer Simulation; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Models, Biological; Nonlinear Dynamics; Pain; Pain Measurement; Patient Dropouts; Probability; Randomized Controlled Trials as Topic; Thiophenes | 2014 |
Asymmetric synthesis of duloxetine intermediate (S)-(-)-3-N-methylamino-1-(2-thienyl)-1-propanol using immobilized Saccharomyces cerevisiae in liquid-core sodium alginate/chitosan/sodium alginate microcapsules.
Topics: Alginates; Antidepressive Agents; Biomass; Bioreactors; Biotransformation; Capsules; Cells, Immobilized; Chitosan; Duloxetine Hydrochloride; Glucuronic Acid; Hexuronic Acids; Hydrogen-Ion Concentration; Molecular Weight; Oxidation-Reduction; Propanols; Saccharomyces cerevisiae; Thiophenes | 2014 |
Pain management discussion forum: serious interaction among frequently used drugs for chronic pain.
Topics: Analgesics; Analgesics, Opioid; Chronic Pain; Dose-Response Relationship, Drug; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Serotonin Syndrome; Thiophenes; Tramadol | 2014 |
Pharmacoscintigraphic evaluation of potential of lipid nanocarriers for nose-to-brain delivery of antidepressant drug.
Topics: Administration, Intranasal; Animals; Antidepressive Agents; Brain; Drug Carriers; Duloxetine Hydrochloride; Female; Glycerides; Male; Nanostructures; Nasal Mucosa; Polymers; Propylene Glycols; Rabbits; Radionuclide Imaging; Rats, Wistar; Technetium; Thiophenes; Tissue Distribution | 2014 |
Multimodal antidepressant vortioxetine increases frontal cortical oscillations unlike escitalopram and duloxetine--a quantitative EEG study in rats.
Topics: Animals; Antidepressive Agents; Citalopram; Duloxetine Hydrochloride; Electroencephalography; Frontal Lobe; Male; Piperazines; Rats, Sprague-Dawley; Receptors, Serotonin; RNA-Binding Proteins; Sulfides; Thiophenes; Vortioxetine; Wakefulness | 2014 |
Serotonin-norepinephrine reuptake inhibitor-associated mixed episode in an adolescent with schizoaffective disorder.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Bipolar Disorder; Depressive Disorder; Duloxetine Hydrochloride; Female; Humans; Psychotic Disorders; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2014 |
Cost effectiveness of duloxetine for osteoarthritis: a Quebec societal perspective.
Topics: Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Cost-Benefit Analysis; Duloxetine Hydrochloride; Female; Humans; Male; Markov Chains; Middle Aged; Osteoarthritis; Quebec; Socioeconomic Factors; Thiophenes | 2014 |
Determination of duloxetine in human plasma with proven lack of influence of the major metabolite 4-hydroxyduloxetine.
Topics: Chromatography, High Pressure Liquid; Drug Monitoring; Duloxetine Hydrochloride; Humans; Liquid-Liquid Extraction; Plasma; Reproducibility of Results; Thiophenes; Ultraviolet Rays | 2014 |
Coding of adverse events of suicidality in clinical study reports of duloxetine for the treatment of major depressive disorder: descriptive study.
Topics: Adrenergic Uptake Inhibitors; Adverse Drug Reaction Reporting Systems; Antidepressive Agents; Clinical Coding; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Suicide; Thiophenes | 2014 |
Digging for data on harms in duloxetine trials.
Topics: Adrenergic Uptake Inhibitors; Adverse Drug Reaction Reporting Systems; Antidepressive Agents; Clinical Coding; Clinical Trials as Topic; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Suicide; Thiophenes | 2014 |
Augmentation of antidepressant effects of duloxetine and bupropion by caffeine in mice.
Topics: Animals; Antidepressive Agents; Brain; Bupropion; Caffeine; Chromatography, High Pressure Liquid; Drug Interactions; Duloxetine Hydrochloride; Male; Mice; Neurotransmitter Agents; Spectrometry, Fluorescence; Thiophenes | 2014 |
Efficacy of drugs with different mechanisms of action in relieving spontaneous pain at rest and during movement in a rat model of osteoarthritis.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Duloxetine Hydrochloride; Gait; Iodoacetic Acid; Male; Morphine; Movement; Osteoarthritis; Pain; Rats; Rest; Thiophenes; Tramadol; Weight-Bearing | 2014 |
Effects of low-dose olanzapine on duloxetine-related nausea and vomiting for the treatment of major depressive disorder.
Topics: Adolescent; Adult; Antidepressive Agents; Antiemetics; Benzodiazepines; Depressive Disorder, Major; Drug Administration Schedule; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Nausea; Olanzapine; Thiophenes; Treatment Outcome; Vomiting; Young Adult | 2014 |
Pharmacokinetics of orally administered duloxetine in children and adolescents with major depressive disorder.
Topics: Administration, Oral; Adolescent; Age Factors; Antidepressive Agents; Child; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Humans; Models, Biological; Randomized Controlled Trials as Topic; Thiophenes | 2014 |
Total synthesis of fluoxetine and duloxetine through an in situ imine formation/borylation/transimination and reduction approach.
Topics: Chemistry, Organic; Duloxetine Hydrochloride; Fluoxetine; Imines; Thiophenes | 2014 |
Development of chiral methodologies by capillary electrophoresis with ultraviolet and mass spectrometry detection for duloxetine analysis in pharmaceutical formulations.
Topics: Duloxetine Hydrochloride; Electrophoresis, Capillary; Mass Spectrometry; Spectrophotometry, Ultraviolet; Stereoisomerism; Thiophenes | 2014 |
Individual residual symptoms and functional impairment in patients with depression.
Topics: Adult; Antidepressive Agents; Anxiety; Depression; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Pain; Sleep Wake Disorders; Thiophenes | 2014 |
Chronic treatment with prazosin or duloxetine lessens concurrent anxiety-like behavior and alcohol intake: evidence of disrupted noradrenergic signaling in anxiety-related alcohol use.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic Uptake Inhibitors; Alcohol Drinking; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Duloxetine Hydrochloride; Ethanol; Male; Prazosin; Rats; Rats, Long-Evans; Self Administration; Thiophenes | 2014 |
Managing urinary incontinence: what works?
Topics: Biocompatible Materials; Botulinum Toxins; Duloxetine Hydrochloride; Electric Stimulation Therapy; Exercise Therapy; Female; Humans; Muscarinic Antagonists; Pelvic Floor; Suburethral Slings; Thiophenes; Urinary Catheterization; Urinary Incontinence | 2014 |
[What will not be publicized].
Topics: Depressive Disorder; Drug Approval; Duloxetine Hydrochloride; Germany; Humans; Publication Bias; Randomized Controlled Trials as Topic; Thiophenes | 2014 |
Study of the enantioseparation capability of chiral dual system based on chondroitin sulfate C in CE.
Topics: Atenolol; beta-Cyclodextrins; Buffers; Cetirizine; Chlorpheniramine; Chondroitin Sulfates; Duloxetine Hydrochloride; Electrophoresis, Capillary; Glycogen; Hydrogen-Ion Concentration; Imidazoles; Isoquinolines; Nefopam; Stereoisomerism; Thiophenes | 2015 |
Copper-catalysed selective hydroamination reactions of alkynes.
Topics: Alkynes; Amination; Amines; Atomoxetine Hydrochloride; Benzhydryl Compounds; Catalysis; Copper; Cresols; Duloxetine Hydrochloride; Fluoxetine; Phenylpropanolamine; Propylamines; Stereoisomerism; Thiophenes; Tolterodine Tartrate | 2015 |
Usefulness of duloxetine for Paclitaxel-induced peripheral neuropathy treatment in gynecological cancer patients.
Topics: Adult; Aged; Analgesics; Antineoplastic Agents, Phytogenic; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Ovarian Neoplasms; Paclitaxel; Peripheral Nervous System Diseases; Retrospective Studies; Thiophenes; Treatment Outcome | 2015 |
The safety of duloxetine during pregnancy and lactation.
Topics: Antidepressive Agents; Depression; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Humans; Infant; Lactation; Milk, Human; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Thiophenes | 2014 |
ZnCl2 -promoted asymmetric hydrogenation of β-secondary-amino ketones catalyzed by a P-chiral Rh-bisphosphine complex.
Topics: Amination; Amino Alcohols; Atomoxetine Hydrochloride; Catalysis; Chlorides; Coordination Complexes; Duloxetine Hydrochloride; Fluoxetine; Hydrogenation; Ketones; Phosphines; Propylamines; Rhodium; Stereoisomerism; Thiophenes; Zinc Compounds | 2015 |
Effects of Duloxetine on Urethral Continence Reflex and Bladder Activity in Rats with Cerebral Infarction.
Topics: Animals; Cerebral Infarction; Duloxetine Hydrochloride; Female; Rats; Rats, Sprague-Dawley; Reflex; Selective Serotonin Reuptake Inhibitors; Sneezing; Thiophenes; Urethra; Urinary Bladder; Urination | 2015 |
[Microtubule polymerization inhibitors].
Topics: Duloxetine Hydrochloride; Furans; Humans; Ketones; Microtubules; Neoplasms; Thiophenes; Tubulin Modulators; Vinca Alkaloids | 2015 |
Another cause of headache after epidural injection.
Topics: Aged; Duloxetine Hydrochloride; Female; Humans; Hyponatremia; Injections, Epidural; Intervertebral Disc Displacement; Post-Dural Puncture Headache; Sciatica; Selective Serotonin Reuptake Inhibitors; Sodium; Spinal Stenosis; Thiophenes | 2015 |
Multimodal functional and structural neuroimaging investigation of major depressive disorder following treatment with duloxetine.
Topics: Adult; Brain; Brain Mapping; Depressive Disorder, Major; Duloxetine Hydrochloride; Echo-Planar Imaging; Emotions; Facial Expression; Female; Functional Neuroimaging; Humans; Imaging, Three-Dimensional; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Multimodal Imaging; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Stroop Test; Thiophenes | 2015 |
[A case of Paclitaxel-induced peripheral neuropathy successfully treated with duloxetine].
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Duloxetine Hydrochloride; Female; Humans; Middle Aged; Paclitaxel; Peripheral Nervous System Diseases; Thiophenes; Trastuzumab | 2015 |
The Local and Systemic Actions of Duloxetine in Allodynia and Hyperalgesia Using a Rat Skin Incision Pain Model.
Topics: Administration, Cutaneous; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Cells, Cultured; Dermatologic Surgical Procedures; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hyperalgesia; Injections, Intraperitoneal; Male; Pain Measurement; Pain, Postoperative; Pituitary Gland; Rats, Sprague-Dawley; Sciatic Nerve; Sodium Channel Blockers; Sodium Channels; Thiophenes; Time Factors | 2015 |
Antihyperalgesic effect of duloxetine and amitriptyline in rats after peripheral nerve injury: Influence of descending noradrenergic plasticity.
Topics: Amitriptyline; Analgesics; Animals; Duloxetine Hydrochloride; Hyperalgesia; Lumbosacral Region; Male; Neuronal Plasticity; Norepinephrine; Rats, Sprague-Dawley; Serotonin; Spinal Cord Dorsal Horn; Spinal Nerves; Thiophenes; Time Factors | 2015 |
[Serotonin syndrome associated with the administration of duloxetine; report of a case].
Topics: Antidepressive Agents; Duloxetine Hydrochloride; Humans; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Syndrome; Thiophenes | 2016 |
Antidepressant-like Effects of ZBH2012001, a Novel Potent Serotonin and Norepinephrine Reuptake Inhibitor.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Benzodioxoles; Calcium; Cyclic AMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; HEK293 Cells; Helplessness, Learned; Hindlimb Suspension; Humans; Inhibitory Concentration 50; Locomotion; Male; Mice; Mice, Inbred ICR; Protein Binding; Rats; Rats, Sprague-Dawley; Serotonin and Noradrenaline Reuptake Inhibitors; Swimming; Thiophenes | 2016 |
Questions Regarding "Efficacy of Duloxetine in Chronic Low Back Pain with a Neuropathic Component".
Topics: Analgesics; Chronic Pain; Duloxetine Hydrochloride; Humans; Low Back Pain; Neuralgia; Pain Measurement; Peripheral Nervous System Diseases; Thiophenes | 2016 |
Pharmacokinetic profiles contribute to the differences in behavioral pharmacology of 071031B enantiomers as novel serotonin and norepinephrine reuptake inhibitors.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzodioxoles; Depression; Depressive Disorder; Duloxetine Hydrochloride; Male; Mice; Mice, Inbred ICR; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin and Noradrenaline Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Swimming; Thiophenes | 2017 |
Duloxetine: urinary incontinence and marketing authorization incontinence.
Topics: Duloxetine Hydrochloride; Humans; Marketing; Selective Serotonin Reuptake Inhibitors; Thiophenes; Urinary Incontinence | 2017 |
Effects of Magnesium Oxide on the Serum Duloxetine Concentration and Antidepressant-Like Effects of Duloxetine in Rats.
Topics: Animals; Antidepressive Agents; Chromatography, High Pressure Liquid; Constipation; Depression; Drug Interactions; Duloxetine Hydrochloride; Magnesium Oxide; Male; Norepinephrine; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Swimming; Thiophenes | 2018 |
Repurposing Drugs for Post-COVID-19 Fatigue Syndrome: Methylphenidate, Duloxetine, and Brexpiprazole.
Topics: COVID-19; Drug Repositioning; Duloxetine Hydrochloride; Fatigue; Humans; Methylphenidate; Quinolones; Thiophenes | 2022 |
Determination of Patient Adherence for Duloxetine in Urine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Creatinine; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Norepinephrine; Patient Compliance; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Young Adult | 2022 |
Letter to Editor on "Duloxetine induced tachychardia: A rare side effect".
Topics: Duloxetine Hydrochloride; Humans; Thiophenes | 2023 |