Page last updated: 2024-08-24

duloxetine hydrochloride and morphine

duloxetine hydrochloride has been researched along with morphine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (12.50)29.6817
2010's12 (50.00)24.3611
2020's9 (37.50)2.80

Authors

AuthorsStudies
Jones, CK; Peters, SC; Shannon, HE1
Leventhal, L; Piesla, M; Wantuch, C1
Cummons, TA; Harrison, JE; Leventhal, L; Lu, P; Piesla, MJ; Strassle, BW; Whiteside, GT1
Dyhr, H; Grunnet, M; Munro, G1
Chia, SL; Ho, KY; Liu, H; Lo, NN; Tay, W; Yeo, MC; Yeo, SJ1
Bannon, AW; Decker, MW; Gauvin, D; Hsieh, GC; Joshi, SK; Lee, CH; Lewis, LG; Mikusa, J; Mills, CD; Rueter, LE; Zhong, C; Zhu, CZ1
Dyhr, H; Erichsen, HK; Hansen, MK; Marcher, L; Munro, G; Sheykhzade, M; Storm, A1
Miyazaki, R; Yamamoto, T1
Elmes, SJ; McIntosh, F; Perkins, MN; Rashid, MH; Theberge, Y1
Badghisi, H; Meske, DS; Ossipov, MH; Oyarzo, J; Porreca, F; Xie, JY1
Martin, WJ; Obedencio, GP; Shen, F; Smith, JA; Tsuruda, PR1
Dickenson, AH1
Authier, N; Balayssac, D; Eschalier, A; Ferrier, J; Ling, B; Pereira, B1
Ishikawa, G; Nagakura, Y; Shimizu, Y; Takeshita, N1
Natsume, T; Ogawa, S; Takamatsu, H1
Braden, K; Chen, Z; Doyle, TM; Jacobson, KA; Salvemini, D; Samson, WK; Stockstill, K; Tosh, DK; Wahlman, C; Yosten, GL1
Bai, J; Jiang, S; Xia, R; Yan, L1
Badgaiyan, RD; Gupta, K; Jarrett, S; Palzer, EF; Sagi, V; Tran, H1
Elgalaly, NA; Hetta, DF; Mohammad, MAF1
Abdelghafar, EM; Elrawas, MM; Kilany, AM; Othman, AH; Shaker, EH1
de Oliveira Filho, GR; Erdmann, TR; Gaspareto, PB; Gerber, MT1
Cao, J; Ding, ZC; Huang, C; Li, H; Wang, HY; Yuan, MC; Zhou, ZK1
Bomfati, F; de Oliveira Filho, GR; Erdmann, TR; Gaspareto, PB; Gerber, MT; Lyra, HF1
Abdelfatah Mohamed, M; Ahmed, MI; Elgalaly, NA; Elmorabaa, HA; Fuad Hetta, D; Kamal, SM1

Trials

7 trial(s) available for duloxetine hydrochloride and morphine

ArticleYear
Duloxetine reduces morphine requirements after knee replacement surgery.
    British journal of anaesthesia, 2010, Volume: 105, Issue:3

    Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Double-Blind Method; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Care; Selective Serotonin Reuptake Inhibitors; Thiophenes; Young Adult

2010
The Efficacy of Preoperative Duloxetine in Patients Undergoing Major Abdominal Cancer Surgery: A Randomized Controlled Trial.
    The Clinical journal of pain, 2021, 12-01, Volume: 37, Issue:12

    Topics: Analgesics, Opioid; Double-Blind Method; Duloxetine Hydrochloride; Humans; Morphine; Neoplasms; Pain Measurement; Pain, Postoperative

2021
The role of duloxetine in reducing opioid consumption after thoracotomy: a prospective, randomized, double-blinded, placebo-controlled pilot trial.
    Minerva anestesiologica, 2022, Volume: 88, Issue:10

    Topics: Analgesia, Epidural; Analgesics, Opioid; Capsules; Double-Blind Method; Duloxetine Hydrochloride; Humans; Isoflurane; Morphine; Pain Measurement; Pain, Postoperative; Pilot Projects; Prospective Studies; Thoracotomy

2022
The effects of a short-term perioperative duloxetine treatment on post-colectomy pain: A randomized, controlled clinical trial.
    Journal of clinical anesthesia, 2022, Volume: 82

    Topics: Analgesics, Opioid; Colectomy; Double-Blind Method; Duloxetine Hydrochloride; Humans; Morphine; Pain, Postoperative; Prospective Studies

2022
Significant Analgesic Benefits of Perioperative Duloxetine in Patients Who Have Depressive Symptoms Undergoing Total Hip Arthroplasty: A Randomized Controlled Trial.
    The Journal of arthroplasty, 2023, Volume: 38, Issue:3

    Topics: Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Depression; Double-Blind Method; Duloxetine Hydrochloride; Humans; Morphine; Pain, Postoperative; Treatment Outcome

2023
Efficacy of postoperative analgesia with duloxetine in posthemorrhoidectomy pain: a prospective, randomized, double-blind and placebo-controlled trial.
    BMC anesthesiology, 2022, 12-01, Volume: 22, Issue:1

    Topics: Analgesia; Drug-Related Side Effects and Adverse Reactions; Duloxetine Hydrochloride; Humans; Morphine; Pain; Prospective Studies

2022
Efficacy of perioperative duloxetine as a part of multimodal analgesia in laparoscopic colorectal cancer surgeries.
    BMC anesthesiology, 2023, 05-16, Volume: 23, Issue:1

    Topics: Analgesia; Analgesics, Opioid; Colorectal Neoplasms; Double-Blind Method; Duloxetine Hydrochloride; Humans; Laparoscopy; Morphine; Pain, Postoperative

2023

Other Studies

17 other study(ies) available for duloxetine hydrochloride and morphine

ArticleYear
Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Amines; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Ibuprofen; Inflammation; Male; Mice; Morphine; Norepinephrine; Pain; Pain Measurement; Postural Balance; Rats; Rats, Sprague-Dawley; Reaction Time; Selective Serotonin Reuptake Inhibitors; Thiophenes

2005
Pharmacological validation of a model of cystitis pain in the mouse.
    Neuroscience letters, 2007, Jun-29, Volume: 421, Issue:3

    Topics: Analgesics; Animals; Behavior, Animal; Cyclophosphamide; Cystitis; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Ketorolac; Male; Mice; Morphine; Pain; Pain Measurement; Thiophenes

2007
Abnormal gait, due to inflammation but not nerve injury, reflects enhanced nociception in preclinical pain models.
    Brain research, 2009, Oct-27, Volume: 1295

    Topics: Amines; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Axotomy; Carrageenan; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Edema; Freund's Adjuvant; Gabapentin; Gait; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Indomethacin; Inflammation; Male; Morphine; Neuralgia; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Thiophenes

2009
Selective potentiation of gabapentin-mediated antinociception in the rat formalin test by the nicotinic acetylcholine receptor agonist ABT-594.
    Neuropharmacology, 2010, Volume: 59, Issue:3

    Topics: Amines; Analgesics; Animals; Azetidines; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Duloxetine Hydrochloride; Exploratory Behavior; Gabapentin; gamma-Aminobutyric Acid; Male; Mecamylamine; Morphine; Nicotinic Agonists; Nicotinic Antagonists; Pain; Pain Measurement; Pyridines; Rats; Rats, Sprague-Dawley; Thiophenes

2010
Assessing carrageenan-induced locomotor activity impairment in rats: comparison with evoked endpoint of acute inflammatory pain.
    European journal of pain (London, England), 2012, Volume: 16, Issue:6

    Topics: Acute Pain; Adrenergic Uptake Inhibitors; Amines; Amphetamine; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Carrageenan; Central Nervous System Stimulants; Cyclohexanecarboxylic Acids; Diclofenac; Disease Models, Animal; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Ibuprofen; Lameness, Animal; Male; Morphine; Motor Activity; Neuritis; Rats; Rats, Sprague-Dawley; Thiophenes

2012
The combined predictive capacity of rat models of algogen-induced and neuropathic hypersensitivity to clinically used analgesics varies with nociceptive endpoint and consideration of locomotor function.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:3

    Topics: Amines; Analgesics; Animals; Capsaicin; Cyclohexanecarboxylic Acids; Disease Models, Animal; Duloxetine Hydrochloride; Exploratory Behavior; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Locomotion; Male; Morphine; Neuralgia; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Thiophenes

2012
The efficacy of morphine, pregabalin, gabapentin, and duloxetine on mechanical allodynia is different from that on neuroma pain in the rat neuropathic pain model.
    Anesthesia and analgesia, 2012, Volume: 115, Issue:1

    Topics: Administration, Oral; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Morphine; Neuralgia; Neuroma; Pain Measurement; Pain Threshold; Pregabalin; Rats; Rats, Sprague-Dawley; Thiophenes; Time Factors

2012
Pharmacological validation of early and late phase of rat mono-iodoacetate model using the Tekscan system.
    European journal of pain (London, England), 2013, Volume: 17, Issue:2

    Topics: Alkylating Agents; Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Chronic Disease; Dexamethasone; Dinoprostone; Disease Models, Animal; Duloxetine Hydrochloride; Hindlimb; Iodoacetates; Male; Morphine; Muscle Fibers, Skeletal; Naproxen; Neurons, Afferent; Pain Measurement; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Restraint, Physical; Synovial Fluid; Thiophenes; Weight-Bearing

2013
Opioid and noradrenergic contributions of tapentadol in experimental neuropathic pain.
    Neuroscience letters, 2014, Mar-06, Volume: 562

    Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Duloxetine Hydrochloride; Male; Morphine; Neuralgia; Norepinephrine; Pain Measurement; Phenols; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Nerves; Tapentadol; Thiophenes

2014
Relative contributions of norepinephrine and serotonin transporters to antinociceptive synergy between monoamine reuptake inhibitors and morphine in the rat formalin model.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Analgesia; Animals; Atomoxetine Hydrochloride; Biogenic Monoamines; Chromatography, Liquid; Drug Synergism; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Morphine; Morpholines; Neurotransmitter Uptake Inhibitors; Nociceptive Pain; Norepinephrine Plasma Membrane Transport Proteins; Ondansetron; Propylamines; Rats; Rotarod Performance Test; Serotonin Plasma Membrane Transport Proteins; Tandem Mass Spectrometry; Thiophenes

2013
Commentary on: Opioid and noradrenergic contributions of tapentadol in experimental neuropathic pain.
    Neuroscience letters, 2014, Mar-06, Volume: 562

    Topics: Analgesics, Opioid; Animals; Duloxetine Hydrochloride; Male; Morphine; Neuralgia; Phenols; Spinal Nerves; Tapentadol; Thiophenes

2014
Assessment of thermal sensitivity in rats using the thermal place preference test: description and application in the study of oxaliplatin-induced acute thermal hypersensitivity and inflammatory pain models.
    Behavioural pharmacology, 2014, Volume: 25, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Animals; Carrageenan; Cold Temperature; Conditioning, Psychological; Disease Models, Animal; Duloxetine Hydrochloride; Hot Temperature; Hyperalgesia; Male; Morphine; Organoplatinum Compounds; Oxaliplatin; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Space Perception; Temperature; Thiophenes

2014
Efficacy of drugs with different mechanisms of action in relieving spontaneous pain at rest and during movement in a rat model of osteoarthritis.
    European journal of pharmacology, 2014, Sep-05, Volume: 738

    Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Duloxetine Hydrochloride; Gait; Iodoacetic Acid; Male; Morphine; Movement; Osteoarthritis; Pain; Rats; Rest; Thiophenes; Tramadol; Weight-Bearing

2014
[Pharmacological profile of a novel nonhuman primate model of knee osteoarthritis].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2018, Volume: 152, Issue:3

    Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aprepitant; Diclofenac; Duloxetine Hydrochloride; Knee Joint; Morphine; Neurokinin-1 Receptor Antagonists; Osteoarthritis, Knee; Pain; Primates; Serotonin and Noradrenaline Reuptake Inhibitors

2018
Sexually dimorphic therapeutic response in bortezomib-induced neuropathic pain reveals altered pain physiology in female rodents.
    Pain, 2020, Volume: 161, Issue:1

    Topics: Adenosine A3 Receptor Antagonists; Analgesics, Opioid; Animals; Antineoplastic Agents; Bortezomib; Duloxetine Hydrochloride; Female; Fingolimod Hydrochloride; Male; Morphine; Neuralgia; Oxaliplatin; Paclitaxel; Rats; Receptor, Adenosine A3; Sex Factors; Sphingosine 1 Phosphate Receptor Modulators; Sphingosine-1-Phosphate Receptors; Spinal Cord Dorsal Horn

2020
Successful Reversal of Opioid-Induced Hyperalgesia and Allodynia with Duloxetine.
    Pain medicine (Malden, Mass.), 2021, 04-20, Volume: 22, Issue:4

    Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Duloxetine Hydrochloride; Humans; Hyperalgesia; Morphine; Neuralgia

2021
Diet and companionship modulate pain via a serotonergic mechanism.
    Scientific reports, 2021, 02-01, Volume: 11, Issue:1

    Topics: Analgesics, Opioid; Anemia, Sickle Cell; Animals; Chronic Pain; Diet; Disease Models, Animal; Duloxetine Hydrochloride; Female; Fenclonine; Hyperalgesia; Interpersonal Relations; Male; Mice; Mice, Transgenic; Morphine; Serotonin; Serotonin and Noradrenaline Reuptake Inhibitors; Serotonin Antagonists; Signal Transduction; Spinal Cord

2021