Page last updated: 2024-08-24

duloxetine hydrochloride and fluoxetine

duloxetine hydrochloride has been researched along with fluoxetine in 68 studies

Research

Studies (68)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (7.35)	18.2507
2000's	15 (22.06)	29.6817
2010's	34 (50.00)	24.3611
2020's	14 (20.59)	2.80

Authors

Authors	Studies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Cistarelli, JM; Gobert, A; Millan, MJ; Rivet, JM	1
Lakoski, JM; Smith, JE	2
Cistarelli, L; Gobert, A; Melon, C; Millan, MJ; Rivet, JM	1
Lucki, I; Rénéric, JP	1
Demitrack, MA; Goldstein, DJ; Lu, Y; Mallinckrodt, C	1
Audia, JE; Katofiasc, MA; Nissen, J; Thor, KB	1
Hemrick-Luecke, SK; Iyengar, S; Simmons, RM; Webster, AA; Xu, JY	1
Greist, J; Mallinckrodt, CH; McNamara, RK; Raskin, J; Rayamajhi, JN	1
Fava, M; Hazen, E	1
Eckert, L; Lançon, C	1
Cookson, J; Desaiah, D; Gilaberte, I; Kajdasz, DK	1
Eastwood, BJ; Jones, CK; Need, AB; Shannon, HE	1
Detke, MJ; Faries, DE; Mallinckrodt, CH; Meyers, AL; Prakash, A	1
Detke, MJ; Ossanna, MJ; Pritchett, YL; Swindle, RW; Thase, ME; Xu, J	1
Detke, MJ; Fava, M; Houston, JP; Mallinckrodt, CH; Prakash, A; Swindle, R	1
Carvalho, LA; Gorenstein, C; Markus, RP; Moreno, R; Pariante, C	1
Apfeldorf, WJ; Cullen, CE; Eide, CE; Lu, BY; Williams, CC	1
Baker, SJ; Boyce-Rustay, JM; Decker, MW; Honore, P; Kohnken, R; Simler, GH; Wensink, EJ; Zhong, C	1
Argento, V; Blagodatny, M; Liu, PT; Skudlarska, B	1
Lucassen, PJ; Marlatt, MW; van Praag, H	1
Kourti, PV; Samanidou, VF	1
Chapman, A; Delivuk, M; Gartlehner, G; Gaynes, BN; Kaminski, A; Thaler, K	1
Chen, NH; Li, J; Liu, Y; Sun, JD; Yuan, YH	1
Kovatsi, L; Livanos, A; Njau, S; Pantazidou, K; Samanidou, V	1
Fan, DS; Guo, L; Ji, CX; Li, W; Liang, ZL; Xu, RM; Zhang, JJ	1
Barbui, C; Cipriani, A; Furukawa, TA; Koesters, M; Nosè, M; Omori, IM; Purgato, M; Trespidi, C	1
Clarke, G; Cryan, JF; Dinan, TG; Griffin, BT; O'Brien, FE	1
Martin, WJ; Obedencio, GP; Shen, F; Smith, JA; Tsuruda, PR	1
Fang, Q; Hu, YH; Li, S; Wu, FF; Wu, J; Xie, LJ; Yang, LY; Zhou, JN	1
Atkinson, SD; Bangs, ME; Emslie, GJ; March, JS; Pangallo, BA; Prakash, A; Zhang, Q	1
Bangs, ME; Emslie, GJ; March, JS; Pangallo, BA; Prakash, A; Zhang, Q	1
Calow, AD; Fernández, E; Whiting, A	1
Gu, S; Guo, J; Luo, H; Qu, W; Tang, Q	1
Buchwald, SL; Shi, SL	1
Hu, Q; Imamoto, T; Liu, Y; Zhang, W; Zhang, Z	1
Dueñas, H; Haro, JM; Hong, J; Moneta, MV; Montgomery, W; Novick, D; Peng, X	1
Bangs, ME; Emslie, GJ; March, JS; Pangallo, BA; Prakash, A; Wells, TG; Zhang, Q	1
Berquist, MD; Mooney-Leber, SM; Pehrson, AL; Porter, JH; Porter, NP; Prus, AJ	1
Chen, F; Sánchez, C; Waller, JA	1
Ceci, A; Doods, H; Hu, B; Treede, RD	1
Cipriani, A; Coghill, D; Cohen, D; Cuijpers, P; Del Giovane, C; Hazell, P; Hetrick, SE; Leucht, S; Liu, L; Liu, Y; Michael, KD; Pu, J; Qin, B; Ravindran, AV; Whittington, C; Xie, P; Yang, L; Zhang, Y; Zhou, X	1
Gulinello, M; Li, Y; Sanchez, C	1
Chekroud, AM; Gueorguieva, R; Krystal, JH	1
Chen, M; Hoshino, H; Obata, H; Saito, S; Yang, Y	1
Jiao, Y; Liang, Y; Lin, J; Qu, H; Sun, Y; Xu, J; Zhao, C	1
Gilron, I; Moore, RA; Shum, B; Thorpe, J; Wiffen, PJ	1
Jiao, X; Li, Y; Liang, M; Tang, B; Wang, X; Xiao, Y; Xie, X	1
Carleton, BC; Etminan, M; Guo, MY; Kezouh, A; Kim, DD; Procyshyn, RM; Samii, A	1
Buchanan, GF; Dayton, KG; Kruse, SW; Purnell, BS; Rosner, JI	1
Bellin, G; Ferroni, L; Gardin, C; Pavan, C; Vindigni, V; Zavan, B	1
Feng, S; Gu, J; Jiang, X; Tang, S; Wang, L; Zheng, L	1
Barata, C; Gómez-Canela, C; Marcé, RM; Martínez-Jerónimo, F; Rovira García, X	1
Chapman, A; Gartlehner, G; Gaynes, BN; Nussbaumer-Streit, B; Probst, T; Sönnichsen, A; Thaler, K; Winkler, D	1
Bonci, A; Marino, RAM; McDevitt, RA; Tejeda, HA	1
Badcock, PB; Bailey, AP; Cox, GR; Hetrick, SE; McKenzie, JE; Meader, N; Merry, SN; Moller, CI; Sharma, V	1
Haas, DM; Marks, C; Quinney, SK; Silvola, R; Teal, E	1
Bonds, JA; Brooker, SM; Kessler, JA; McGuire, TL; Peng, CY; Rawat, R; Tsai, YH; Tunc-Ozcan, E	1
Athreya, AP; Bobo, WV; Croarkin, PE; Emslie, GJ; Kennard, BD; Leffler, JM; Mayes, T; McKean, AJ; Rackley, SJ; Romanowicz, M; Shekunov, J; Trivedi, M; Vande Voort, JL; Wang, L; Weinshilboum, RM	1
Chen, B; Gao, N; Hu, G; Li, Y; Wang, R; Xu, T; Zhang, X	1
Bracke, F; Frieling, H; Leffler, A	1
Chen, B; Fang, L; Qian, J; Sun, W; Tong, S; You, H	1
Chen, KY; Li, RY	1
Hatano, M; Ikuta, T; Iwata, N; Kishi, T; Matsuda, Y; Okuya, M; Sakuma, K	1
Eap, CB; Favre, L; Frantz, J; Garin, P; Vandenberghe, F; Vionnet, N	1
Asadi-Pooya, AA; Firouzabadi, N; Kashkooli, M; Malekpour, M; Zamiri, B	1
Cao, Q; Rao, Y; Yang, R; Zhao, J	1

Reviews

11 review(s) available for duloxetine hydrochloride and fluoxetine

Article	Year
Duloxetine compared with fluoxetine and venlafaxine: use of meta-regression analysis for indirect comparisons. BMC psychiatry, 2006, Jul-24, Volume: 6 Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Cyclohexanols; Depressive Disorder, Major; Duloxetine Hydrochloride; Fluoxetine; Humans; Randomized Controlled Trials as Topic; Regression Analysis; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride	2006
Efficacy of duloxetine and selective serotonin reuptake inhibitors: comparisons as assessed by remission rates in patients with major depressive disorder. Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:6 Topics: Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Fluoxetine; Humans; Paroxetine; Placebos; Randomized Controlled Trials as Topic; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome	2007
Second-generation antidepressants for seasonal affective disorder. The Cochrane database of systematic reviews, 2011, Dec-07, Issue:12 Topics: Adult; Antidepressive Agents, Second-Generation; Citalopram; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Morpholines; Phototherapy; Randomized Controlled Trials as Topic; Reboxetine; Seasonal Affective Disorder; Thiophenes	2011
Duloxetine versus other anti-depressive agents for depression. The Cochrane database of systematic reviews, 2012, Oct-17, Volume: 10 Topics: Antidepressive Agents; Citalopram; Cyclohexanols; Depression; Desvenlafaxine Succinate; Dibenzothiazepines; Duloxetine Hydrochloride; Fluoxetine; Humans; Paroxetine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Thiophenes; Venlafaxine Hydrochloride	2012
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis. Lancet (London, England), 2016, Aug-27, Volume: 388, Issue:10047 Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Confounding Factors, Epidemiologic; Depressive Disorder, Major; Desipramine; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Evidence-Based Medicine; Fluoxetine; Humans; Imipramine; Mianserin; Mirtazapine; Nortriptyline; Paroxetine; Piperazines; Randomized Controlled Trials as Topic; Research Design; Sertraline; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride	2016
Combination pharmacotherapy for the treatment of fibromyalgia in adults. The Cochrane database of systematic reviews, 2018, 02-19, Volume: 2 Topics: 5-Hydroxytryptophan; Acetaminophen; Adult; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Benzodiazepines; Carisoprodol; Drug Therapy, Combination; Duloxetine Hydrochloride; Fibromyalgia; Fluoxetine; Humans; Magnesium; Malates; Melatonin; Monoamine Oxidase Inhibitors; Muscle Relaxants, Central; Pregabalin; Randomized Controlled Trials as Topic	2018
Second-generation antidepressants for treatment of seasonal affective disorder. The Cochrane database of systematic reviews, 2021, 03-04, Volume: 3 Topics: Adult; Antidepressive Agents, Second-Generation; Bias; Citalopram; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Morpholines; Observational Studies as Topic; Phototherapy; Placebos; Quality of Life; Randomized Controlled Trials as Topic; Reboxetine; Seasonal Affective Disorder; Thiophenes; Treatment Outcome	2021
New generation antidepressants for depression in children and adolescents: a network meta-analysis. The Cochrane database of systematic reviews, 2021, 05-24, Volume: 5 Topics: Adolescent; Antidepressive Agents; Bias; Child; Citalopram; Depressive Disorder, Major; Desvenlafaxine Succinate; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Mirtazapine; Network Meta-Analysis; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Suicidal Ideation; Venlafaxine Hydrochloride; Vilazodone Hydrochloride; Vortioxetine	2021
Efficacy and safety of different antidepressants and anticonvulsants in central poststroke pain: A network meta-analysis and systematic review. PloS one, 2022, Volume: 17, Issue:10 Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents; Carbamazepine; Duloxetine Hydrochloride; Fluoxetine; Gabapentin; Humans; Lamotrigine; Multicenter Studies as Topic; Network Meta-Analysis; Neuralgia; Pregabalin; Randomized Controlled Trials as Topic; Vitamins	2022
Antidepressants for the treatment of adults with major depressive disorder in the maintenance phase: a systematic review and network meta-analysis. Molecular psychiatry, 2023, Volume: 28, Issue:1 Topics: Adult; Amitriptyline; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Desvenlafaxine Succinate; Duloxetine Hydrochloride; Female; Fluoxetine; Fluvoxamine; Humans; Mirtazapine; Network Meta-Analysis; Paroxetine; Randomized Controlled Trials as Topic; Reboxetine; Sertraline; Venlafaxine Hydrochloride; Vortioxetine	2023
Efficacy and tolerability of antidepressant drugs in treatment of depression in children and adolescents: a network meta-analysis. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2022, Aug-01, Volume: 51, Issue:4 Topics: Adolescent; Amitriptyline; Antidepressive Agents; Child; Depression; Depressive Disorder, Major; Duloxetine Hydrochloride; Escitalopram; Fluoxetine; Humans; Imipramine; Network Meta-Analysis; Paroxetine; Sertraline; Venlafaxine Hydrochloride	2022

Trials

10 trial(s) available for duloxetine hydrochloride and fluoxetine

Article	Year
Duloxetine in the treatment of major depressive disorder: a double-blind clinical trial. The Journal of clinical psychiatry, 2002, Volume: 63, Issue:3 Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Blood Pressure; Body Weight; Depressive Disorder, Major; Dopamine Uptake Inhibitors; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome	2002
Incidence and duration of antidepressant-induced nausea: duloxetine compared with paroxetine and fluoxetine. Clinical therapeutics, 2004, Volume: 26, Issue:9 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antidepressive Agents; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Europe; Female; Fluoxetine; Humans; Male; Middle Aged; Nausea; Paroxetine; Prevalence; Severity of Illness Index; Sex Factors; Thiophenes; Time Factors; United States	2004
Treatment benefits of duloxetine in major depressive disorder as assessed by number needed to treat. International clinical psychopharmacology, 2006, Volume: 21, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Paroxetine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome	2006
Differential antidepressant symptom efficacy: placebo-controlled comparisons of duloxetine and SSRIs (fluoxetine, paroxetine, escitalopram). Neuropsychobiology, 2007, Volume: 56, Issue:2-3 Topics: Adult; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Paroxetine; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Treatment Outcome	2007
Effect of antidepressants on melatonin metabolite in depressed patients. Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:3 Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Hypericum; Male; Melatonin; Middle Aged; Plant Extracts; Severity of Illness Index; Thiophenes; Treatment Outcome	2009
A double-blind efficacy and safety study of duloxetine flexible dosing in children and adolescents with major depressive disorder. Journal of child and adolescent psychopharmacology, 2014, Volume: 24, Issue:4 Topics: Adolescent; Antidepressive Agents; Child; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Suicidal Ideation; Suicide; Thiophenes; Treatment Outcome	2014
A double-blind efficacy and safety study of duloxetine fixed doses in children and adolescents with major depressive disorder. Journal of child and adolescent psychopharmacology, 2014, Volume: 24, Issue:4 Topics: Adolescent; Antidepressive Agents; Child; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Suicidal Ideation; Suicide; Thiophenes; Treatment Outcome	2014
Effects of olanzapine-fluoxetine combination treatment of major depressive disorders on the quality of life during acute treatment period. Cell biochemistry and biophysics, 2014, Volume: 70, Issue:3 Topics: Adult; Benzodiazepines; Depressive Disorder, Major; Drug Administration Schedule; Drug Combinations; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Quality of Life; Sleep Wake Disorders; Somatoform Disorders; Thiophenes	2014
Acute and longer-term safety results from a pooled analysis of duloxetine studies for the treatment of children and adolescents with major depressive disorder. Journal of child and adolescent psychopharmacology, 2015, Volume: 25, Issue:4 Topics: Adolescent; Antidepressive Agents; Child; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Suicidal Ideation	2015
Trajectories of relapse in randomised, placebo-controlled trials of treatment discontinuation in major depressive disorder: an individual patient-level data meta-analysis. The lancet. Psychiatry, 2017, Volume: 4, Issue:3 Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Meta-Analysis as Topic; Middle Aged; Patient Dropouts; Placebo Effect; Protective Factors; Recurrence; Severity of Illness Index; Time Factors; Treatment Outcome; Withholding Treatment	2017

Other Studies

47 other study(ies) available for duloxetine hydrochloride and fluoxetine

Article	Year
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Buspirone enhances duloxetine- and fluoxetine-induced increases in dialysate levels of dopamine and noradrenaline, but not serotonin, in the frontal cortex of freely moving rats. Journal of neurochemistry, 1997, Volume: 68, Issue:3 Topics: Animals; Buspirone; Dopamine; Duloxetine Hydrochloride; Fluoxetine; Frontal Lobe; Male; Microdialysis; Norepinephrine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Thiophenes	1997
Electrophysiological effects of fluoxetine and duloxetine in the dorsal raphe nucleus and hippocampus. European journal of pharmacology, 1997, Mar-26, Volume: 323, Issue:1 Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Electrophysiology; Fluoxetine; Hippocampus; Infusions, Intravenous; Iontophoresis; Male; Neurons; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Thiophenes	1997
Alpha2-adrenergic receptor blockade markedly potentiates duloxetine- and fluoxetine-induced increases in noradrenaline, dopamine, and serotonin levels in the frontal cortex of freely moving rats. Journal of neurochemistry, 1997, Volume: 69, Issue:6 Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Biogenic Monoamines; Dopamine; Duloxetine Hydrochloride; Fluoxetine; Frontal Lobe; Male; Norepinephrine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes	1997
Antidepressant behavioral effects by dual inhibition of monoamine reuptake in the rat forced swimming test. Psychopharmacology, 1998, Volume: 136, Issue:2 Topics: Animals; Antidepressive Agents; Behavior, Animal; Bupropion; Cyclopropanes; Desipramine; Duloxetine Hydrochloride; Fluoxetine; Male; Milnacipran; Motor Activity; Rats; Rats, Sprague-Dawley; Thiophenes	1998
Cellular electrophysiological effects of chronic fluoxetine and duloxetine administration on serotonergic responses in the aging hippocampus. Synapse (New York, N.Y.), 1998, Volume: 30, Issue:3 Topics: Aging; Animals; Antidepressive Agents; Drug Administration Schedule; Duloxetine Hydrochloride; Electrophysiology; Evoked Potentials; Female; Fluoxetine; Hippocampus; Pyramidal Cells; Rats; Rats, Inbred F344; Serotonin; Thiophenes	1998
Comparison of the effects of serotonin selective, norepinephrine selective, and dual serotonin and norepinephrine reuptake inhibitors on lower urinary tract function in cats. Life sciences, 2002, Aug-02, Volume: 71, Issue:11 Topics: Acetic Acid; Administration, Intravesical; Adrenergic Uptake Inhibitors; Animals; Cats; Cyclohexanols; Duloxetine Hydrochloride; Electromyography; Female; Fluoxetine; Humans; Methiothepin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Thiophenes; Urethra; Urinary Bladder; Venlafaxine Hydrochloride	2002
Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:2 Topics: Acute Disease; Amines; Amitriptyline; Animals; Conscious Sedation; Cyclohexanecarboxylic Acids; Cyclohexanols; Cyclopropanes; Disease Models, Animal; Drug Therapy, Combination; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Methyltyrosines; Milnacipran; Neuromuscular Junction; Norepinephrine; p-Chloroamphetamine; Pain; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Thiophenes; Venlafaxine Hydrochloride	2004
Successful treatment with duloxetine in a case of treatment refractory bulimia nervosa: a case report. Journal of psychopharmacology (Oxford, England), 2006, Volume: 20, Issue:5 Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Bulimia; Drug Resistance; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes	2006
Analgesic effects of serotonergic, noradrenergic or dual reuptake inhibitors in the carrageenan test in rats: evidence for synergism between serotonergic and noradrenergic reuptake inhibition. Neuropharmacology, 2006, Volume: 51, Issue:7-8 Topics: Adrenergic Uptake Inhibitors; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Chemistry; Carrageenan; Cyclohexanols; Desipramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Duloxetine Hydrochloride; Edema; Fluoxetine; Hot Temperature; Hyperalgesia; Male; Norepinephrine; Paroxetine; Pressure; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline; Thiophenes; Venlafaxine Hydrochloride	2006
Simple options for improving signal detection in antidepressant clinical trials. Psychopharmacology bulletin, 2007, Volume: 40, Issue:2 Topics: Antidepressive Agents; Citalopram; Clinical Trials as Topic; Databases, Factual; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Fluoxetine; Likelihood Functions; Models, Statistical; Paroxetine; Personality Inventory; Placebo Effect; Psychometrics; Reproducibility of Results; Research Design; Signal Detection, Psychological; Thiophenes; Treatment Outcome	2007
Antidepressant-induced sweating alleviated by aripiprazole. Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:6 Topics: Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Dopamine Agonists; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Hyperhidrosis; Middle Aged; Piperazines; Quinolones; Sweating; Thiophenes	2008
Comparison of mechanical allodynia and the affective component of inflammatory pain in rats. Neuropharmacology, 2010, Volume: 58, Issue:2 Topics: Analgesics, Non-Narcotic; Animals; Behavior, Animal; Celecoxib; Central Nervous System Agents; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Escape Reaction; Fluoxetine; Inflammation; Male; Motor Activity; Neuropsychological Tests; Pain; Pain Measurement; Physical Stimulation; Pyrazoles; Rats; Rats, Sprague-Dawley; Scopolamine; Sulfonamides; Thiophenes; Treatment Outcome	2010
Serotonin syndrome in an octogenarian after switch from fluoxetine to duloxetine. Journal of the American Geriatrics Society, 2009, Volume: 57, Issue:12 Topics: Aged, 80 and over; Duloxetine Hydrochloride; Fluoxetine; Humans; Male; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Thiophenes	2009
Comparison of neurogenic effects of fluoxetine, duloxetine and running in mice. Brain research, 2010, Jun-23, Volume: 1341 Topics: Animals; Behavior, Animal; Cell Proliferation; Cell Survival; Duloxetine Hydrochloride; Female; Fluoxetine; Hippocampus; Mice; Mice, Inbred C57BL; Motor Activity; Neurogenesis; Neuronal Plasticity; Neurons; Physical Conditioning, Animal; Selective Serotonin Reuptake Inhibitors; Thiophenes	2010
Rapid HPLC method for the simultaneous monitoring of duloxetine, venlaflaxine, fluoxetine and paroxetine in biofluids. Bioanalysis, 2009, Volume: 1, Issue:5 Topics: Chromatography, High Pressure Liquid; Cyclohexanols; Duloxetine Hydrochloride; Fluoxetine; Humans; Limit of Detection; Paroxetine; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Sensitivity and Specificity; Thiophenes; Venlafaxine Hydrochloride	2009
Gap junction dysfunction in the prefrontal cortex induces depressive-like behaviors in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:5 Topics: Analysis of Variance; Animals; Carbenoxolone; Connexin 43; Disease Models, Animal; Duloxetine Hydrochloride; Electroshock; Exploratory Behavior; Fluoxetine; Food Deprivation; Food Preferences; Gap Junctions; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hormone Antagonists; Inhibition, Psychological; Isoquinolines; Male; Microscopy, Electron, Transmission; Mifepristone; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Restraint, Physical; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Social Isolation; Stress, Psychological; Sucrose; Sweetening Agents; Swimming; Thiophenes	2012
A simple HPLC method for the simultaneous determination of two selective serotonin reuptake inhibitors and two serotonin-norepinephrine reuptake inhibitors in hair, nail clippings, and cerebrospinal fluid. Journal of separation science, 2012, Volume: 35, Issue:7 Topics: Adrenergic Uptake Inhibitors; Biological Transport; Cerebrospinal Fluid; Chromatography, High Pressure Liquid; Cyclohexanols; Duloxetine Hydrochloride; Fluoxetine; Hair; Humans; Nails; Norepinephrine; Paroxetine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Venlafaxine Hydrochloride	2012
Evaluation of the anti-ulcerogenic activity of the antidepressants duloxetine, amitriptyline, fluoxetine and mirtazapine in different models of experimental gastric ulcer in rats. European journal of pharmacology, 2012, Sep-15, Volume: 691, Issue:1-3 Topics: Amitriptyline; Animals; Anti-Ulcer Agents; Antidepressive Agents; Disease Models, Animal; Duloxetine Hydrochloride; Fluoxetine; Immersion; Indomethacin; Male; Mianserin; Mirtazapine; Rats; Rats, Sprague-Dawley; Reserpine; Restraint, Physical; Stomach Ulcer; Stress, Psychological; Thiophenes; Water	2012
Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability. The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:10 Topics: Amitriptyline; Animals; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Capillary Permeability; Dogs; Duloxetine Hydrochloride; Fluoxetine; Humans; Imipramine; Madin Darby Canine Kidney Cells; Mianserin; Mirtazapine; Thiophenes; Transfection	2013
Relative contributions of norepinephrine and serotonin transporters to antinociceptive synergy between monoamine reuptake inhibitors and morphine in the rat formalin model. PloS one, 2013, Volume: 8, Issue:9 Topics: Analgesia; Animals; Atomoxetine Hydrochloride; Biogenic Monoamines; Chromatography, Liquid; Drug Synergism; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Morphine; Morpholines; Neurotransmitter Uptake Inhibitors; Nociceptive Pain; Norepinephrine Plasma Membrane Transport Proteins; Ondansetron; Propylamines; Rats; Rotarod Performance Test; Serotonin Plasma Membrane Transport Proteins; Tandem Mass Spectrometry; Thiophenes	2013
Copper(II)-catalyzed enantioselective hydrosilylation of halo-substituted alkyl aryl and heteroaryl ketones: asymmetric synthesis of (R)-fluoxetine and (S)-duloxetine. Organic & biomolecular chemistry, 2014, Feb-14, Volume: 12, Issue:6 Topics: Catalysis; Copper; Duloxetine Hydrochloride; Fluoxetine; Ketones; Molecular Conformation; Organometallic Compounds; Stereoisomerism; Thiophenes	2014
Total synthesis of fluoxetine and duloxetine through an in situ imine formation/borylation/transimination and reduction approach. Organic & biomolecular chemistry, 2014, Aug-28, Volume: 12, Issue:32 Topics: Chemistry, Organic; Duloxetine Hydrochloride; Fluoxetine; Imines; Thiophenes	2014
Copper-catalysed selective hydroamination reactions of alkynes. Nature chemistry, 2015, Volume: 7, Issue:1 Topics: Alkynes; Amination; Amines; Atomoxetine Hydrochloride; Benzhydryl Compounds; Catalysis; Copper; Cresols; Duloxetine Hydrochloride; Fluoxetine; Phenylpropanolamine; Propylamines; Stereoisomerism; Thiophenes; Tolterodine Tartrate	2015
ZnCl2 -promoted asymmetric hydrogenation of β-secondary-amino ketones catalyzed by a P-chiral Rh-bisphosphine complex. Angewandte Chemie (International ed. in English), 2015, Feb-09, Volume: 54, Issue:7 Topics: Amination; Amino Alcohols; Atomoxetine Hydrochloride; Catalysis; Chlorides; Coordination Complexes; Duloxetine Hydrochloride; Fluoxetine; Hydrogenation; Ketones; Phosphines; Propylamines; Rhodium; Stereoisomerism; Thiophenes; Zinc Compounds	2015
Real-world outcomes in patients with depression treated with duloxetine or a selective serotonin reuptake inhibitor in East Asia. Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists, 2016, Volume: 8, Issue:1 Topics: Adult; Asia, Eastern; Citalopram; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Pain; Paroxetine; Prospective Studies; Quality of Life; Regression Analysis; Remission Induction; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Sertraline; Severity of Illness Index; Treatment Outcome	2016
The antidepressant drugs fluoxetine and duloxetine produce anxiolytic-like effects in a schedule-induced polydipsia paradigm in rats: enhancement of fluoxetine's effects by the α2 adrenoceptor antagonist yohimbine. Behavioural pharmacology, 2015, Volume: 26, Issue:5 Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Anti-Anxiety Agents; Antidepressive Agents; Disease Models, Animal; Drinking; Drinking Water; Duloxetine Hydrochloride; Fluoxetine; Food Deprivation; Male; Polydipsia; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Yohimbine	2015
Vortioxetine promotes maturation of dendritic spines in vitro: A comparative study in hippocampal cultures. Neuropharmacology, 2016, Volume: 103 Topics: Animals; Antidepressive Agents; Cells, Cultured; Dendritic Spines; Duloxetine Hydrochloride; Fluoxetine; Hippocampus; Ketamine; Piperazines; Rats, Sprague-Dawley; Serotonin and Noradrenaline Reuptake Inhibitors; Sulfides; Synapses; Vortioxetine	2016
Duloxetine and 8-OH-DPAT, but not fluoxetine, reduce depression-like behaviour in an animal model of chronic neuropathic pain. Neuroscience letters, 2016, Apr-21, Volume: 619 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Neurons; Analgesics; Animals; Antidepressive Agents; Behavior, Animal; Chronic Disease; Depression; Duloxetine Hydrochloride; Fluoxetine; Hyperalgesia; Male; Neuralgia; Norepinephrine; Rats, Wistar; Serotonergic Neurons; Serotonin	2016
Distinct Antidepressant-Like and Cognitive Effects of Antidepressants with Different Mechanisms of Action in Middle-Aged Female Mice. The international journal of neuropsychopharmacology, 2017, 06-01, Volume: 20, Issue:6 Topics: Aging; Animals; Antidepressive Agents; Cognition; Cohort Studies; Depression; Duloxetine Hydrochloride; Female; Fluoxetine; Memory; Mice, Inbred C57BL; Piperazines; Psychotropic Drugs; Random Allocation; Space Perception; Sulfides; Vilazodone Hydrochloride; Visual Perception; Vortioxetine	2017
Spinal dopaminergic involvement in the antihyperalgesic effect of antidepressants in a rat model of neuropathic pain. Neuroscience letters, 2017, 05-10, Volume: 649 Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclopropanes; Disease Models, Animal; Dopamine; Dopamine Antagonists; Duloxetine Hydrochloride; Fluoxetine; Hyperalgesia; Male; Milnacipran; Neuralgia; Pain Threshold; Rats, Sprague-Dawley; Spinal Cord Dorsal Horn; Sulpiride	2017
Comparative efficacy and acceptability of antidepressant treatment in poststroke depression: a multiple-treatments meta-analysis. BMJ open, 2017, Aug-03, Volume: 7, Issue:8 Topics: Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Depression; Depressive Disorder; Doxepin; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Morpholines; Paroxetine; Patient Acceptance of Health Care; Reboxetine; Selective Serotonin Reuptake Inhibitors; Stroke; Treatment Outcome	2017
Evaluating Drug-Induced Liver Injury and Its Remission via Discrimination and Imaging of HClO and H Analytical chemistry, 2018, 06-19, Volume: 90, Issue:12 Topics: Antidepressive Agents; Chemical and Drug Induced Liver Injury; Duloxetine Hydrochloride; Fluorescent Dyes; Fluoxetine; Humans; Hydrogen Sulfide; Hypochlorous Acid; Molecular Structure; Optical Imaging; Protons	2018
Association of Antidepressant Use With Drug-Related Extrapyramidal Symptoms: A Pharmacoepidemiological Study. Journal of clinical psychopharmacology, 2018, Volume: 38, Issue:4 Topics: Antidepressive Agents; Basal Ganglia Diseases; Bupropion; Case-Control Studies; Citalopram; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Paroxetine; Pharmacoepidemiology; Sertraline; United States; Venlafaxine Hydrochloride	2018
Effect of monoamine reuptake inhibition and α Epilepsia, 2019, Volume: 60, Issue:3 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Atomoxetine Hydrochloride; Citalopram; Duloxetine Hydrochloride; Electroshock; Fluoxetine; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Prazosin; Reboxetine; Seizures; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin and Noradrenaline Reuptake Inhibitors; Sudden Unexpected Death in Epilepsy	2019
Effects of novel antidepressant drugs on mesenchymal stem cell physiology. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 114 Topics: Adipocytes; Adipogenesis; Adipose Tissue; Adult; Antidepressive Agents; Cell Differentiation; Cell Proliferation; Cells, Cultured; Duloxetine Hydrochloride; Fluoxetine; Gene Expression; Humans; Mesenchymal Stem Cells; Osteocytes; Osteogenesis; Osteoporosis; Selective Serotonin Reuptake Inhibitors; Young Adult	2019
In-vitro and in situ assessment of the efflux of five antidepressants by breast cancer resistance protein. The Journal of pharmacy and pharmacology, 2019, Volume: 71, Issue:7 Topics: Amitriptyline; Animals; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Biological Transport; Blood-Brain Barrier; Brain; Cell Line, Tumor; Duloxetine Hydrochloride; Fluoxetine; Humans; Mirtazapine; Neoplasm Proteins; Rats; Rats, Sprague-Dawley; Sertraline	2019
Analysis of neurotransmitters in Daphnia magna affected by neuroactive pharmaceuticals using liquid chromatography-high resolution mass spectrometry. Environmental pollution (Barking, Essex : 1987), 2019, Volume: 254, Issue:Pt B Topics: Animals; Aquatic Organisms; Chromatography, High Pressure Liquid; Daphnia; Duloxetine Hydrochloride; Fluoxetine; Mass Spectrometry; Models, Animal; Neurotransmitter Agents; Sertraline; Venlafaxine Hydrochloride; Water Pollutants, Chemical	2019
Serotonergic inhibition of responding for conditioned but not primary reinforcers. Pharmacology, biochemistry, and behavior, 2021, Volume: 205 Topics: Animals; Citalopram; Conditioning, Classical; Cues; Dorsal Raphe Nucleus; Duloxetine Hydrochloride; Female; Fluoxetine; Gene Knockout Techniques; Male; Mice; Mice, Inbred C57BL; Motivation; Neurons; Reward; Selective Serotonin Reuptake Inhibitors; Serotonin; Tryptophan Hydroxylase	2021
Comparing newborn outcomes after prenatal exposure to individual antidepressants: A retrospective cohort study. Pharmacotherapy, 2021, Volume: 41, Issue:11 Topics: Antidepressive Agents; Bupropion; Citalopram; Duloxetine Hydrochloride; Escitalopram; Female; Fluoxetine; Humans; Infant, Newborn; Pregnancy; Prenatal Exposure Delayed Effects; Retrospective Studies; Sertraline; Treatment Outcome; Venlafaxine Hydrochloride	2021
Hippocampal BMP signaling as a common pathway for antidepressant action. Cellular and molecular life sciences : CMLS, 2021, Dec-22, Volume: 79, Issue:1 Topics: Aging; Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Bone Morphogenetic Proteins; Dentate Gyrus; Duloxetine Hydrochloride; Electroconvulsive Therapy; Fluoxetine; Ganglia, Spinal; Hippocampus; Mice, Inbred C57BL; Mice, Transgenic; Neurogenesis; Signal Transduction; Stress, Psychological; Trazodone; Vilazodone Hydrochloride	2021
Evidence for machine learning guided early prediction of acute outcomes in the treatment of depressed children and adolescents with antidepressants. Journal of child psychology and psychiatry, and allied disciplines, 2022, Volume: 63, Issue:11 Topics: Adolescent; Antidepressive Agents; Artificial Intelligence; Child; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Fluoxetine; Humans; Machine Learning; Treatment Outcome	2022
Inhibitory effects of fluoxetine and duloxetine on the pharmacokinetics of metoprolol in vivo and in vitro. Fundamental & clinical pharmacology, 2022, Volume: 36, Issue:6 Topics: Animals; Chromatography, Liquid; Cytochrome P-450 CYP2D6; Duloxetine Hydrochloride; Fluoxetine; Humans; Metoprolol; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry	2022
Antidepressants Are Poor Inhibitors of Heat-Evoked Ion Currents Mediated by TRPM2. Pharmacology, 2022, Volume: 107, Issue:9-10 Topics: Adenosine Diphosphate Ribose; Amitriptyline; Animals; Antidepressive Agents; Citalopram; Duloxetine Hydrochloride; Fluoxetine; HEK293 Cells; Hot Temperature; Humans; Ketamine; Lidocaine; Mice; Paroxetine; Pregabalin; Sertraline; TRPM Cation Channels	2022
Enantioseparation of N-methyl duloxetine, duloxetine, and fluoxetine by countercurrent chromatography using anionic β-cyclodextrin as chiral selector. Journal of separation science, 2022, Volume: 45, Issue:15 Topics: Anions; beta-Cyclodextrins; Countercurrent Distribution; Duloxetine Hydrochloride; Ethers; Fluoxetine; Phosphates; Solvents; Stereoisomerism	2022
The Influence of a Roux-en-Y Gastric Bypass on Plasma Concentrations of Antidepressants. Obesity surgery, 2023, Volume: 33, Issue:5 Topics: Adult; Antidepressive Agents; Duloxetine Hydrochloride; Escitalopram; Female; Fluoxetine; Gastric Bypass; Humans; Obesity, Morbid; Prospective Studies; Retrospective Studies; Trazodone	2023
FKBP5 blockade may provide a new horizon for the treatment of stress-associated disorders: An in-silico study. Epilepsia open, 2023, Volume: 8, Issue:2 Topics: Citalopram; Clomipramine; Duloxetine Hydrochloride; Fluoxetine; Humans; Sertraline; United States	2023