Page last updated: 2024-08-24

duloxetine hydrochloride and amitriptyline

duloxetine hydrochloride has been researched along with amitriptyline in 66 studies

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (3.03)18.2507
2000's8 (12.12)29.6817
2010's38 (57.58)24.3611
2020's18 (27.27)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Ikeda, M; Kihara, T1
Eigyo, M; Ibii, N; Ikeda, M; Ishibashi, C; Katoh, A; Matsushita, A; Naitoh, Y; Takeuchi, M1
Hemrick-Luecke, SK; Iyengar, S; Simmons, RM; Webster, AA; Xu, JY1
Blackburn-Munro, G; Bomholt, SF; Mikkelsen, JD1
D'Souza, DN; Iyengar, S; Pritchett, YL; Raskin, J; Smith, TR; Wernicke, JF; Wong, K1
Birnbaum, HG; Gelwicks, S; Le, TK; Mareva, MN; Robinson, RL; Rosen, A; Wu, EQ1
Brown, DR; Keegan, MT; Rabinstein, AA1
Baglioni, P; Govindan, J; Khan, A1
Chappell, AS; D'Souza, DN; Iyengar, S; Pritchett, YL; Raskin, J; Smith, TR; Wang, F; Wernicke, JF1
Beard, SM; Garcia-Cebrian, A; Le, TK; Malik, RA; McCrink, L; Monz, B1
Bowrin, K; Choy, E; Lloyd, A; Richards, S; Sadosky, A; Watson, P; Zlateva, G1
Ferrari, G; Gemignani, F; Giovanelli, M; Macaluso, C; Marbini, A; Vitetta, F1
Häuser, W; Petzke, F; Sommer, C; Üçeyler, N1
Bansal, D; Bhansali, A; Chakrabarti, A; Dutta, P; Hota, D; Kaur, H1
Alten, R; Bär, KJ; Häuser, W; Petzke, F; Sommer, C; Späth, M; Tölle, T; Uçeyler, N; Winkelmann, A; Winter, E1
Fan, DS; Guo, L; Ji, CX; Li, W; Liang, ZL; Xu, RM; Zhang, JJ1
Gordin, VN; Lamberg, JJ1
Boyle, J; Coppini, DV; Eriksson, ME; Gouni, R; Gribble, L; Johnsen, S; Kerr, D1
Avena-Woods, C; Hilas, O1
Bansal, M; Happich, M; Klein, R; Wielage, R; Wilson, K1
May, M; Picksak, G; Stichtenoth, DO1
Kim, SC; Landon, JE; Solomon, DH1
Clarke, G; Cryan, JF; Dinan, TG; Griffin, BT; O'Brien, FE1
Anderson, SG; Dunn, G; Heald, AH; Malipatil, NS; Roberts, H1
Aoki, T; Enomoto, R; Hamakawa, N; Kakimoto, S; Matsuoka, N; Murai, N; Oe, T; Sekizawa, T; Tamura, S; Tsukamoto, M1
Benoliel, R; Haviv, Y; Sharav, Y; Zadik, Y1
Aoki, T; Matsuoka, N; Murai, N; Tamura, S; Tsukamoto, M1
Bak, K; Bleeker, J; Cavaletti, G; Chauhan, C; Dworkin, RH; Gavin, P; Hershman, DL; Lacchetti, C; Lavino, A; Lavoie Smith, EM; Loprinzi, CL; Lustberg, MB; Paice, J; Schneider, B; Smith, ML; Smith, T; Terstriep, S; Wagner-Johnston, N1
Chu, SH; Cleeland, CS; Geng, Y; Lee, ES; Lee, YJ; Wang, XS1
Kim, SC; Landon, JE; Lee, YC1
Arco, L1
Hoshino, H; Obata, H; Saito, S1
Guy, S; Lam, T; Loh, E; Mehta, S; Teasell, R1
Kiss, G1
Blum, LM; Scanlon, KA; Starkey, SJ; Stoppacher, R1
Cipriani, A; Coghill, D; Cohen, D; Cuijpers, P; Del Giovane, C; Hazell, P; Hetrick, SE; Leucht, S; Liu, L; Liu, Y; Michael, KD; Pu, J; Qin, B; Ravindran, AV; Whittington, C; Xie, P; Yang, L; Zhang, Y; Zhou, X1
Mehta, AK; Tripathi, CD; Yadav, AM1
Gibbs, LM; Lindsay, TJ; Snyder, MJ1
Chen, M; Hoshino, H; Obata, H; Saito, S; Yang, Y1
Alten, R; Bär, KJ; Bernateck, M; Brückle, W; Friedel, E; Häuser, W; Henningsen, P; Petzke, F; Sommer, C; Tölle, T; Üçeyler, N; Winkelmann, A1
Gilron, I; Moore, RA; Shum, B; Thorpe, J; Wiffen, PJ1
Parke, SC; Reyes, MR1
Barrot, M; Ceredig, RA; Chavant, V; Daniel, D; Ernst, C; Gilsbach, R; Goumon, Y; Joganah, LE; Kremer, M; Lacaud, A; Lelievre, V; Lutz, PE; Massotte, D; Megat, S; Nexon, L; Salvat, E; Théroux, JF; Turecki, G; Wurtz, X; Yalcin, I1
Bortolami, O; Bowler, H; Bradburn, M; Cooper, C; Julious, S; Loban, A; Petrie, J; Selvarajah, D; Sutherland, K; Swaby, L; Tesfaye, S; White, D1
Dorsey, SG; Griffioen, MA; O'Toole, RV; Renn, CL; Ziegler, ML1
Falcon, M; Fernandez-Lopez, L; Luna Maldonado, A; Mancini, R; Pellegrini, M; Rotolo, MC1
Feng, S; Gu, J; Jiang, X; Tang, S; Wang, L; Zheng, L1
Holper, L1
de Assis, MR; Dos Santos Paiva, E; Helfenstein, M; Heymann, RE; Martinez, JE; Pollak, DF; Provenza, JR; Ranzolin, A; Rezende, MC; Ribeiro, LS; Souza, EJR1
Amador, TA; da Silva Dal Pizzol, T; de Farias, ÁD; Eberle, L1
Balayssac, D; Busserolles, J; Farsi, F; Guastella, V; Kerckhove, N; Merle, P; Pereira, B; Pezet, D; Selvy, M1
Barros, CM; Boralli, VB; Costa, LH; Galdino, G; Kawano, T; Placido, RV; Podesta, MHMC; Rodrigues, RF; Santos, RS1
Alberti, FF; Becker, MW; Blatt, CR; da Silva Dal Pizzol, T; Pilger, D; Ziegelmann, PK1
Bracke, F; Frieling, H; Leffler, A1
Doucette, JA; Eguale, T; Farag, HM; Goswami, H; Sultan, I; Yunusa, I1
Ahmed, SH; Alam, U; Bennett, DL; Bouhassira, D; Bradburn, M; Cooper, C; Devers, M; Gandhi, R; Glover, R; Gouni, R; Hariman, C; Horspool, M; Johnson, M; Jude, EB; Julious, S; Loban, A; Maguire, D; McDougall, C; Petrie, J; Rajbhandari, S; Rayman, G; Rice, ASC; Selvarajah, D; Sharma, S; Sloan, G; Sutherland, K; Tesfaye, S; Tsatlidis, V; Turton, E; Vas, P; Waterhouse, S; White, D1
Capon, C; Crevant, A; Moreau, N; Pointin, A; Sulukdjian, A1
Chen, KY; Li, RY1
Aster, HC; Braun, A; Evdokimov, D; Sommer, C; Üçeyler, N1
Hatano, M; Ikuta, T; Iwata, N; Kishi, T; Matsuda, Y; Okuya, M; Sakuma, K1
Ahmed, SH; Alam, U; Bennett, DL; Bouhassira, D; Bradburn, M; Cooper, C; Devers, M; Gandhi, R; Glover, R; Gouni, R; Hariman, C; Horspool, M; Johnson, M; Jude, E; Julious, SA; Loban, A; Maguire, D; McDougall, C; Petrie, J; Rajbhandari, S; Rayman, G; Selvarajah, D; Sharma, S; Sloan, G; Sutherland, K; Tesfaye, S; Tsatlidis, V; Turton, E; Vas, P; Waterhouse, S; White, D; Young, T1
Barry, HC1
Chen, H; Chen, SR; Huang, Y; Pan, HL1
Deeney, B; Imison, C; Saul, H; Tesfaye, S1
Cao, Q; Rao, Y; Yang, R; Zhao, J1

Reviews

17 review(s) available for duloxetine hydrochloride and amitriptyline

ArticleYear
Comparative efficacy and acceptability of amitriptyline, duloxetine and milnacipran in fibromyalgia syndrome: a systematic review with meta-analysis.
    Rheumatology (Oxford, England), 2011, Volume: 50, Issue:3

    Topics: Amitriptyline; Antidepressive Agents; Cyclopropanes; Duloxetine Hydrochloride; Fibromyalgia; Humans; Milnacipran; Thiophenes; Treatment Outcome

2011
[Drug therapy of fibromyalgia syndrome. Systematic review, meta-analysis and guideline].
    Schmerz (Berlin, Germany), 2012, Volume: 26, Issue:3

    Topics: Amitriptyline; Analgesics; Analgesics, Opioid; Antidepressive Agents; Anxiety Disorders; Combined Modality Therapy; Comorbidity; Cooperative Behavior; Depressive Disorder, Major; Duloxetine Hydrochloride; Fibromyalgia; gamma-Aminobutyric Acid; Germany; Humans; Interdisciplinary Communication; Off-Label Use; Patient Care Team; Pregabalin; Somatoform Disorders; Thiophenes

2012
Cost-effectiveness of duloxetine in chronic low back pain: a Quebec societal perspective.
    Spine, 2013, May-15, Volume: 38, Issue:11

    Topics: Age Factors; Aged; Amitriptyline; Analgesics; Cardiovascular Diseases; Celecoxib; Chronic Disease; Clinical Trials as Topic; Cost-Benefit Analysis; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Humans; Hydromorphone; Low Back Pain; Markov Chains; Middle Aged; Models, Economic; Naproxen; Ontario; Osteoarthritis; Outcome Assessment, Health Care; Oxycodone; Pregabalin; Pyrazoles; Quality-Adjusted Life Years; Quebec; Sulfonamides; Thiophenes

2013
Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Jun-20, Volume: 32, Issue:18

    Topics: Adult; Amines; Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Antineoplastic Agents; Baclofen; Comorbidity; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Duloxetine Hydrochloride; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Gels; Humans; Incidence; Ketamine; Neoplasms; Neuralgia; Peripheral Nervous System Diseases; Quality of Life; Randomized Controlled Trials as Topic; Severity of Illness Index; Survivors; Thiophenes; Treatment Outcome; United States

2014
Current use of drugs affecting the central nervous system for chemotherapy-induced peripheral neuropathy in cancer patients: a systematic review.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015, Volume: 23, Issue:2

    Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents; Antineoplastic Agents; Boronic Acids; Bortezomib; Carbamazepine; Central Nervous System; Cyclohexanols; Duloxetine Hydrochloride; Epothilones; Humans; Neoplasms; Neuralgia; Oxcarbazepine; Peripheral Nervous System Diseases; Pyrazines; Taxoids; Thalidomide; Thiophenes; Venlafaxine Hydrochloride; Vinca Alkaloids

2015
Antidepressants Are Effective in Decreasing Neuropathic Pain After SCI: A Meta-Analysis.
    Topics in spinal cord injury rehabilitation, 2015,Spring, Volume: 21, Issue:2

    Topics: Amitriptyline; Antidepressive Agents; Databases, Factual; Duloxetine Hydrochloride; Humans; Neuralgia; Praziquantel; Randomized Controlled Trials as Topic; Spinal Cord Injuries

2015
[DRUG THERAPY OF NEUROPATHIC PAIN BASED ON THE LATEST RECOMMENDATIONS].
    Ideggyogyaszati szemle, 2015, Mar-30, Volume: 68, Issue:3-4

    Topics: Amines; Amitriptyline; Analgesics, Non-Narcotic; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Practice Guidelines as Topic; Pregabalin; Thiophenes

2015
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
    Lancet (London, England), 2016, Aug-27, Volume: 388, Issue:10047

    Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Confounding Factors, Epidemiologic; Depressive Disorder, Major; Desipramine; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Evidence-Based Medicine; Fluoxetine; Humans; Imipramine; Mianserin; Mirtazapine; Nortriptyline; Paroxetine; Piperazines; Randomized Controlled Trials as Topic; Research Design; Sertraline; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride

2016
Treating Painful Diabetic Peripheral Neuropathy: An Update.
    American family physician, 2016, Aug-01, Volume: 94, Issue:3

    Topics: Administration, Topical; Amines; Amitriptyline; Analgesics; Analgesics, Opioid; Anesthetics, Local; Capsaicin; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Isosorbide Dinitrate; Lidocaine; Phenols; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sensory System Agents; Serotonin and Noradrenaline Reuptake Inhibitors; Tapentadol; Tramadol; Transcutaneous Electric Nerve Stimulation; Vasodilator Agents; Venlafaxine Hydrochloride

2016
[Drug therapy of fibromyalgia syndrome : Updated guidelines 2017 and overview of systematic review articles].
    Schmerz (Berlin, Germany), 2017, Volume: 31, Issue:3

    Topics: Amitriptyline; Anxiety Disorders; Comorbidity; Depressive Disorder; Duloxetine Hydrochloride; Evidence-Based Medicine; Fibromyalgia; Germany; Humans; Practice Guidelines as Topic; Pregabalin; Randomized Controlled Trials as Topic; Societies, Medical

2017
Combination pharmacotherapy for the treatment of fibromyalgia in adults.
    The Cochrane database of systematic reviews, 2018, 02-19, Volume: 2

    Topics: 5-Hydroxytryptophan; Acetaminophen; Adult; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Benzodiazepines; Carisoprodol; Drug Therapy, Combination; Duloxetine Hydrochloride; Fibromyalgia; Fluoxetine; Humans; Magnesium; Malates; Melatonin; Monoamine Oxidase Inhibitors; Muscle Relaxants, Central; Pregabalin; Randomized Controlled Trials as Topic

2018
Comparing the efficacy and safety of duloxetine and amitriptyline in the treatment of fibromyalgia: overview of systematic reviews.
    Advances in rheumatology (London, England), 2020, 07-08, Volume: 60, Issue:1

    Topics: Amitriptyline; Antidepressive Agents; Duloxetine Hydrochloride; Fibromyalgia; Humans; Syndrome; Systematic Reviews as Topic

2020
Comparative efficacy of amitriptyline, duloxetine and pregabalin for treating fibromyalgia in adults: an overview with network meta-analysis.
    Clinical rheumatology, 2022, Volume: 41, Issue:7

    Topics: Adolescent; Adult; Amitriptyline; Child; Duloxetine Hydrochloride; Female; Fibromyalgia; Humans; Network Meta-Analysis; Pain; Pregabalin; Randomized Controlled Trials as Topic

2022
Comparison of Amitriptyline and US Food and Drug Administration-Approved Treatments for Fibromyalgia: A Systematic Review and Network Meta-analysis.
    JAMA network open, 2022, 05-02, Volume: 5, Issue:5

    Topics: Amitriptyline; Duloxetine Hydrochloride; Fatigue; Female; Fibromyalgia; Humans; Male; Middle Aged; Milnacipran; Network Meta-Analysis; Pain; Pregabalin; United States; United States Food and Drug Administration

2022
Efficacy and safety of different antidepressants and anticonvulsants in central poststroke pain: A network meta-analysis and systematic review.
    PloS one, 2022, Volume: 17, Issue:10

    Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents; Carbamazepine; Duloxetine Hydrochloride; Fluoxetine; Gabapentin; Humans; Lamotrigine; Multicenter Studies as Topic; Network Meta-Analysis; Neuralgia; Pregabalin; Randomized Controlled Trials as Topic; Vitamins

2022
Antidepressants for the treatment of adults with major depressive disorder in the maintenance phase: a systematic review and network meta-analysis.
    Molecular psychiatry, 2023, Volume: 28, Issue:1

    Topics: Adult; Amitriptyline; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Desvenlafaxine Succinate; Duloxetine Hydrochloride; Female; Fluoxetine; Fluvoxamine; Humans; Mirtazapine; Network Meta-Analysis; Paroxetine; Randomized Controlled Trials as Topic; Reboxetine; Sertraline; Venlafaxine Hydrochloride; Vortioxetine

2023
Efficacy and tolerability of antidepressant drugs in treatment of depression in children and adolescents: a network meta-analysis.
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2022, Aug-01, Volume: 51, Issue:4

    Topics: Adolescent; Amitriptyline; Antidepressive Agents; Child; Depression; Depressive Disorder, Major; Duloxetine Hydrochloride; Escitalopram; Fluoxetine; Humans; Imipramine; Network Meta-Analysis; Paroxetine; Sertraline; Venlafaxine Hydrochloride

2022

Trials

9 trial(s) available for duloxetine hydrochloride and amitriptyline

ArticleYear
Duloxetine versus routine care in the long-term management of diabetic peripheral neuropathic pain.
    Journal of palliative medicine, 2006, Volume: 9, Issue:1

    Topics: Amines; Amitriptyline; Analysis of Variance; Cyclohexanecarboxylic Acids; Cyclohexanols; Diabetic Neuropathies; Double-Blind Method; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride

2006
Cost-effectiveness of duloxetine versus routine treatment for U.S. patients with diabetic peripheral neuropathic pain.
    The journal of pain, 2006, Volume: 7, Issue:6

    Topics: Adrenergic Uptake Inhibitors; Aged; Amines; Amitriptyline; Analgesia; Analgesics; Brain; Cohort Studies; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Cyclohexanols; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Norepinephrine; Pain Measurement; Pain Threshold; Placebo Effect; Serotonin; Thiophenes; Treatment Outcome; United States; Venlafaxine Hydrochloride

2006
An open-label 52-week clinical extension comparing duloxetine with routine care in patients with diabetic peripheral neuropathic pain.
    Pain medicine (Malden, Mass.), 2007, Volume: 8, Issue:6

    Topics: Acetaminophen; Amitriptyline; Analgesics; Carbamazepine; Diabetes Complications; Diabetic Neuropathies; Diclofenac; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Lipids; Male; Meloxicam; Middle Aged; Neuralgia; Pentoxifylline; Selective Serotonin Reuptake Inhibitors; Thiamine; Thiazines; Thiazoles; Thioctic Acid; Thiophenes; Time; Vitamin B 12

2007
A comparative evaluation of amitriptyline and duloxetine in painful diabetic neuropathy: a randomized, double-blind, cross-over clinical trial.
    Diabetes care, 2011, Volume: 34, Issue:4

    Topics: Adolescent; Adult; Aged; Amitriptyline; Cross-Over Studies; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes; Young Adult

2011
Randomized, placebo-controlled comparison of amitriptyline, duloxetine, and pregabalin in patients with chronic diabetic peripheral neuropathic pain: impact on pain, polysomnographic sleep, daytime functioning, and quality of life.
    Diabetes care, 2012, Volume: 35, Issue:12

    Topics: Aged; Amitriptyline; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pregabalin; Quality of Life; Sleep; Thiophenes; Treatment Outcome

2012
Multicentre, double-blind, crossover trial to identify the Optimal Pathway for TreatIng neurOpathic paiN in Diabetes Mellitus (OPTION-DM): study protocol for a randomised controlled trial.
    Trials, 2018, Oct-22, Volume: 19, Issue:1

    Topics: Amitriptyline; Analgesics; Cross-Over Studies; Diabetic Neuropathies; Double-Blind Method; Drug Therapy, Combination; Duloxetine Hydrochloride; Humans; Multicenter Studies as Topic; Pain Management; Pain Measurement; Pregabalin; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome; United Kingdom

2018
Comparison of amitriptyline supplemented with pregabalin, pregabalin supplemented with amitriptyline, and duloxetine supplemented with pregabalin for the treatment of diabetic peripheral neuropathic pain (OPTION-DM): a multicentre, double-blind, randomise
    Lancet (London, England), 2022, 08-27, Volume: 400, Issue:10353

    Topics: Amitriptyline; Analgesics; Cross-Over Studies; Diabetes Mellitus; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Humans; Neuralgia; Pregabalin; Treatment Outcome

2022
Optimal pharmacotherapy pathway in adults with diabetic peripheral neuropathic pain: the OPTION-DM RCT.
    Health technology assessment (Winchester, England), 2022, Volume: 26, Issue:39

    Topics: Adult; Amitriptyline; Cost-Benefit Analysis; Diabetes Mellitus; Duloxetine Hydrochloride; Humans; Neuralgia; Pregabalin; Quality of Life

2022
Combination therapy for painful diabetic neuropathy is safe and effective.
    BMJ (Clinical research ed.), 2023, 04-21, Volume: 381

    Topics: Amitriptyline; Analgesics; Diabetes Mellitus; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Humans; Pregabalin; Treatment Outcome

2023

Other Studies

40 other study(ies) available for duloxetine hydrochloride and amitriptyline

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effects of duloxetine, a new serotonin and norepinephrine uptake inhibitor, on extracellular monoamine levels in rat frontal cortex.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:1

    Topics: Amitriptyline; Animals; Biological Transport; Cerebral Cortex; Dopamine; Duloxetine Hydrochloride; Male; Maprotiline; Norepinephrine; Nucleus Accumbens; Rats; Rats, Wistar; Serotonin; Thiophenes

1995
Behavioral and electroencephalographic properties of duloxetine (LY248686), a reuptake inhibitor of norepinephrine and serotonin, in mice and rats.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:3

    Topics: 5-Hydroxytryptophan; Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Body Temperature Regulation; Duloxetine Hydrochloride; Electroencephalography; Eyelids; Male; Maprotiline; Mice; Rats; Rats, Wistar; Salivation; Selective Serotonin Reuptake Inhibitors; Tears; Thiophenes; Tremor

1995
Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:2

    Topics: Acute Disease; Amines; Amitriptyline; Animals; Conscious Sedation; Cyclohexanecarboxylic Acids; Cyclohexanols; Cyclopropanes; Disease Models, Animal; Drug Therapy, Combination; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Methyltyrosines; Milnacipran; Neuromuscular Junction; Norepinephrine; p-Chloroamphetamine; Pain; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Thiophenes; Venlafaxine Hydrochloride

2004
Antinociceptive effects of the antidepressants amitriptyline, duloxetine, mirtazapine and citalopram in animal models of acute, persistent and neuropathic pain.
    Neuropharmacology, 2005, Volume: 48, Issue:2

    Topics: Acute Disease; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Chronic Disease; Citalopram; Disease Models, Animal; Duloxetine Hydrochloride; Male; Mianserin; Mirtazapine; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Thiophenes

2005
Serotonin syndrome from the interaction of cyclobenzaprine with other serotoninergic drugs.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:6

    Topics: Aged; Amitriptyline; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Phenelzine; Serotonin Syndrome; Thiophenes

2006
Career lifetime advances and key developments: diabetes.
    Clinical medicine (London, England), 2007, Volume: 7, Issue:3

    Topics: Amines; Amitriptyline; Analgesics; Antidepressive Agents; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Thiophenes

2007
Cost effectiveness of duloxetine in the treatment of diabetic peripheral neuropathic pain in the UK.
    Current medical research and opinion, 2008, Volume: 24, Issue:2

    Topics: Amines; Amitriptyline; Antidepressive Agents; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Econometric; Paclitaxel; Pain Measurement; Prospective Studies; Quality-Adjusted Life Years; Sickness Impact Profile; Thiophenes; Treatment Outcome; United Kingdom

2008
Cost effectiveness of pregabalin in the treatment of fibromyalgia from a UK perspective.
    Current medical research and opinion, 2010, Volume: 26, Issue:4

    Topics: Adult; Amines; Amitriptyline; Analgesics; Antidepressive Agents; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Drug Costs; Duloxetine Hydrochloride; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Markov Chains; Models, Econometric; Pregabalin; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Thiophenes; Tramadol; United Kingdom

2010
Non-length-dependent small fibre neuropathy. Confocal microscopy study of the corneal innervation.
    Journal of neurology, neurosurgery, and psychiatry, 2010, Volume: 81, Issue:7

    Topics: Adult; Amines; Amitriptyline; Analgesics; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Biopsy; Cornea; Crohn Disease; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Electrophysiology; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Microscopy, Confocal; Middle Aged; Nerve Endings; Nerve Fibers; Peripheral Nervous System Diseases; Sensation Disorders; Sjogren's Syndrome; Skin; Thiophenes; Trigeminal Nerve

2010
Evaluation of the anti-ulcerogenic activity of the antidepressants duloxetine, amitriptyline, fluoxetine and mirtazapine in different models of experimental gastric ulcer in rats.
    European journal of pharmacology, 2012, Sep-15, Volume: 691, Issue:1-3

    Topics: Amitriptyline; Animals; Anti-Ulcer Agents; Antidepressive Agents; Disease Models, Animal; Duloxetine Hydrochloride; Fluoxetine; Immersion; Indomethacin; Male; Mianserin; Mirtazapine; Rats; Rats, Sprague-Dawley; Reserpine; Restraint, Physical; Stomach Ulcer; Stress, Psychological; Thiophenes; Water

2012
Serotonin syndrome in a patient with chronic pain polypharmacy.
    Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:8

    Topics: Adult; Amitriptyline; Anti-Allergic Agents; Antidepressive Agents; Carisoprodol; Cetirizine; Chronic Pain; Duloxetine Hydrochloride; Female; Humans; Muscle Relaxants, Central; Narcotics; Polypharmacy; Serotonin Syndrome; Thiophenes; Tramadol

2014
Antidepressant use in underweight older adults.
    The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2012, Volume: 27, Issue:12

    Topics: Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents; Appetite; Body Mass Index; Body Weight; Depressive Disorder, Major; Duloxetine Hydrochloride; Hospitals, University; Humans; Inservice Training; Mianserin; Mirtazapine; Practice Patterns, Physicians'; Retrospective Studies; Thinness; Thiophenes

2012
[Sweating under polypharmacy with tramadol, amitriptyline and duloxetine?].
    Medizinische Monatsschrift fur Pharmazeuten, 2013, Volume: 36, Issue:5

    Topics: Amitriptyline; Analgesics, Opioid; Antidepressive Agents; Antidepressive Agents, Tricyclic; Duloxetine Hydrochloride; Humans; Polypharmacy; Serotonin Syndrome; Sweating; Thiophenes; Tramadol

2013
Clinical characteristics and medication uses among fibromyalgia patients newly prescribed amitriptyline, duloxetine, gabapentin, or pregabalin.
    Arthritis care & research, 2013, Volume: 65, Issue:11

    Topics: Amines; Amitriptyline; Analgesics; Anti-Anxiety Agents; Antidepressive Agents; Cyclohexanecarboxylic Acids; Disease Progression; Duloxetine Hydrochloride; Female; Fibromyalgia; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Pregabalin; Prescription Drugs; Retrospective Studies; Thiophenes; Treatment Outcome

2013
Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability.
    The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:10

    Topics: Amitriptyline; Animals; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Capillary Permeability; Dogs; Duloxetine Hydrochloride; Fluoxetine; Humans; Imipramine; Madin Darby Canine Kidney Cells; Mianserin; Mirtazapine; Thiophenes; Transfection

2013
Socioeconomic deprivation independently predicts symptomatic painful diabetic neuropathy in type 1 diabetes.
    Primary care diabetes, 2014, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amitriptyline; Analgesics; Biomarkers; Body Mass Index; Chi-Square Distribution; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Duloxetine Hydrochloride; England; Female; Glycated Hemoglobin; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Poverty; Prevalence; Risk Assessment; Risk Factors; Severity of Illness Index; Thiophenes; Young Adult

2014
AS1069562, the (+)-isomer of indeloxazine, exerts analgesic effects in a rat model of neuropathic pain with unique characteristics in spinal monoamine turnover.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 348, Issue:3

    Topics: Amitriptyline; Analgesics; Animals; Biogenic Monoamines; Dopamine; Dopamine Plasma Membrane Transport Proteins; Duloxetine Hydrochloride; Gastric Emptying; HEK293 Cells; Humans; Male; Morpholines; Motor Activity; Neuralgia; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Spinal Cord; Stereoisomerism; Thiophenes

2014
Painful traumatic trigeminal neuropathy: an open study on the pharmacotherapeutic response to stepped treatment.
    Journal of oral & facial pain and headache, 2014,Winter, Volume: 28, Issue:1

    Topics: Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Baclofen; Carbamazepine; Clinical Protocols; Cohort Studies; Cyclohexanecarboxylic Acids; Drug Combinations; Duloxetine Hydrochloride; Female; Follow-Up Studies; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Medical Records; Middle Aged; Nortriptyline; Pain; Pain Measurement; Pregabalin; Prognosis; Prospective Studies; Thiophenes; Treatment Outcome; Trigeminal Nerve Injuries; Trigeminal Neuralgia

2014
Antinociceptive effects of AS1069562, the (+)-isomer of indeloxazine, on spinal hypersensitivity induced by intrathecal injection of prostaglandin in mice: comparison with duloxetine and amitriptyline.
    European journal of pharmacology, 2014, Jun-15, Volume: 733

    Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hyperalgesia; Injections, Spinal; Male; Mice, Inbred ICR; Morpholines; Neuralgia; Prostaglandins; Spinal Cord; Stereoisomerism; Thiophenes

2014
Patterns of health care utilization related to initiation of amitriptyline, duloxetine, gabapentin, or pregabalin in fibromyalgia.
    Arthritis research & therapy, 2015, Jan-28, Volume: 17

    Topics: Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Cohort Studies; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Female; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Health Services; Humans; Male; Medication Adherence; Middle Aged; Patient Acceptance of Health Care; Pregabalin

2015
A case study in treating chronic comorbid obsessive-compulsive disorder and depression with behavioral activation and pharmacotherapy.
    Psychotherapy (Chicago, Ill.), 2015, Volume: 52, Issue:2

    Topics: Amitriptyline; Antidepressive Agents; Behavior Therapy; Chronic Disease; Clomipramine; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Lithium Compounds; Male; Middle Aged; Obsessive-Compulsive Disorder; Treatment Outcome

2015
Antihyperalgesic effect of duloxetine and amitriptyline in rats after peripheral nerve injury: Influence of descending noradrenergic plasticity.
    Neuroscience letters, 2015, Aug-18, Volume: 602

    Topics: Amitriptyline; Analgesics; Animals; Duloxetine Hydrochloride; Hyperalgesia; Lumbosacral Region; Male; Neuronal Plasticity; Norepinephrine; Rats, Sprague-Dawley; Serotonin; Spinal Cord Dorsal Horn; Spinal Nerves; Thiophenes; Time Factors

2015
Comprehensive Duloxetine Analysis in a Fatal Overdose.
    Journal of analytical toxicology, 2016, Volume: 40, Issue:2

    Topics: Aged; Alcoholism; Amitriptyline; Depression; Diphenhydramine; Drug Overdose; Duloxetine Hydrochloride; Fatal Outcome; Female; Humans; Selective Serotonin Reuptake Inhibitors

2016
Drug combinations in diabetic neuropathic pain: an experimental validation.
    Journal of basic and clinical physiology and pharmacology, 2016, Nov-01, Volume: 27, Issue:6

    Topics: Amitriptyline; Analgesics; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Male; Neuralgia; Pain Measurement; Pregabalin; Rats; Rats, Wistar; Sitagliptin Phosphate

2016
Spinal dopaminergic involvement in the antihyperalgesic effect of antidepressants in a rat model of neuropathic pain.
    Neuroscience letters, 2017, 05-10, Volume: 649

    Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclopropanes; Disease Models, Animal; Dopamine; Dopamine Antagonists; Duloxetine Hydrochloride; Fluoxetine; Hyperalgesia; Male; Milnacipran; Neuralgia; Pain Threshold; Rats, Sprague-Dawley; Spinal Cord Dorsal Horn; Sulpiride

2017
Autonomic Dysreflexia as a Potential Adverse Effect of Duloxetine and Amitriptyline Combination Therapy: A Case Report.
    PM & R : the journal of injury, function, and rehabilitation, 2019, Volume: 11, Issue:2

    Topics: Adult; Amitriptyline; Analgesics; Autonomic Dysreflexia; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Neuralgia; Spinal Cord Injuries

2019
A Dual Noradrenergic Mechanism for the Relief of Neuropathic Allodynia by the Antidepressant Drugs Duloxetine and Amitriptyline.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018, 11-14, Volume: 38, Issue:46

    Topics: Adult; Aged; Amitriptyline; Animals; Antidepressive Agents; Duloxetine Hydrochloride; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Neuralgia; Norepinephrine; Pain Management; Receptor, Adenosine A2A

2018
Change in Pain Score after Administration of Analgesics for Lower Extremity Fracture Pain during Hospitalization.
    Pain management nursing : official journal of the American Society of Pain Management Nurses, 2019, Volume: 20, Issue:2

    Topics: Adult; Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents; Baclofen; Bones of Lower Extremity; Cohort Studies; Duloxetine Hydrochloride; Female; Fractures, Bone; Gabapentin; Hospitalization; Humans; Male; Middle Aged; Muscle Relaxants, Central; Pain Management; Pain Measurement; Pregabalin; Retrospective Studies

2019
Development and validation of a method for analysing of duloxetine, venlafaxine and amitriptyline in human bone.
    Forensic science international, 2019, Volume: 299

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Duloxetine Hydrochloride; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Ribs; Solid Phase Extraction; Venlafaxine Hydrochloride

2019
In-vitro and in situ assessment of the efflux of five antidepressants by breast cancer resistance protein.
    The Journal of pharmacy and pharmacology, 2019, Volume: 71, Issue:7

    Topics: Amitriptyline; Animals; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Biological Transport; Blood-Brain Barrier; Brain; Cell Line, Tumor; Duloxetine Hydrochloride; Fluoxetine; Humans; Mirtazapine; Neoplasm Proteins; Rats; Rats, Sprague-Dawley; Sertraline

2019
Combining threshold analysis and GRADE to assess sensitivity to bias in antidepressant treatment recommendations adjusted for depression severity.
    Research synthesis methods, 2020, Volume: 11, Issue:2

    Topics: Acetamides; Adult; Amitriptyline; Antidepressive Agents; Bayes Theorem; Citalopram; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Network Meta-Analysis; Paroxetine; Publication Bias; Reproducibility of Results; Severity of Illness Index; Treatment Outcome; Venlafaxine Hydrochloride

2020
Treatment data from the Brazilian fibromyalgia registry (EpiFibro).
    Advances in rheumatology (London, England), 2020, 01-21, Volume: 60, Issue:1

    Topics: Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Brazil; Cohort Studies; Combined Modality Therapy; Cross-Sectional Studies; Drug Therapy, Combination; Duloxetine Hydrochloride; Exercise; Female; Fibromyalgia; Health Education; Humans; Male; Middle Aged; Muscle Stretching Exercises; Pregabalin; Registries

2020
Prevention, diagnosis and management of chemotherapy-induced peripheral neuropathy: a cross-sectional study of French oncologists' professional practices.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021, Volume: 29, Issue:7

    Topics: Adult; Amitriptyline; Antineoplastic Agents; Calcium; Cross-Sectional Studies; Duloxetine Hydrochloride; France; Gabapentin; Humans; Magnesium; Male; Middle Aged; Neurotoxicity Syndromes; Oncologists; Peripheral Nervous System Diseases; Practice Patterns, Physicians'; Pregabalin; Surveys and Questionnaires; Vitamins

2021
Investigation of the Combination of Pregabalin with Duloxetine or Amitriptyline on the Pharmacokinetics and Antiallodynic Effect During Neuropathic Pain in Rats.
    Pain physician, 2021, Volume: 24, Issue:4

    Topics: Amitriptyline; Analgesics; Animals; Disease Models, Animal; Duloxetine Hydrochloride; Hyperalgesia; Male; Neuralgia; Pain Measurement; Pregabalin; Rats; Rats, Wistar

2021
Antidepressants Are Poor Inhibitors of Heat-Evoked Ion Currents Mediated by TRPM2.
    Pharmacology, 2022, Volume: 107, Issue:9-10

    Topics: Adenosine Diphosphate Ribose; Amitriptyline; Animals; Antidepressive Agents; Citalopram; Duloxetine Hydrochloride; Fluoxetine; HEK293 Cells; Hot Temperature; Humans; Ketamine; Lidocaine; Mice; Paroxetine; Pregabalin; Sertraline; TRPM Cation Channels

2022
Botulinum toxin A for management of refractory concurrent buccal and inferior alveolar nerve post-traumatic neuropathies: a case report.
    The Journal of international medical research, 2022, Volume: 50, Issue:9

    Topics: Amitriptyline; Animals; Botulinum Toxins, Type A; Carbamazepine; Clonazepam; Duloxetine Hydrochloride; Humans; Mandibular Nerve; Neuralgia; Pregabalin; Quality of Life; Venlafaxine Hydrochloride

2022
Analgesic Medication in Fibromyalgia Patients: A Cross-Sectional Study.
    Pain research & management, 2022, Volume: 2022

    Topics: Acetaminophen; Amitriptyline; Analgesics; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cross-Sectional Studies; Dipyrone; Duloxetine Hydrochloride; Fibromyalgia; Humans; Neuralgia; Pregabalin; Selective Serotonin Reuptake Inhibitors

2022
Amitriptyline, Duloxetine, and Pregabalin Each Effective in Decreasing Pain From Diabetic Peripheral Neuropathy; Combinations Even Better.
    American family physician, 2023, Volume: 107, Issue:3

    Topics: Amitriptyline; Analgesics; Diabetes Mellitus; Diabetic Neuropathies; Duloxetine Hydrochloride; Humans; Pain; Pregabalin

2023
Duloxetine and Amitriptyline Reduce Neuropathic Pain by Inhibiting Primary Sensory Input to Spinal Dorsal Horn Neurons via α1- and α2-Adrenergic Receptors.
    ACS chemical neuroscience, 2023, 04-05, Volume: 14, Issue:7

    Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Duloxetine Hydrochloride; Hyperalgesia; Neuralgia; Norepinephrine; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Spinal Cord Dorsal Horn; Yohimbine

2023