dt 5461 has been researched along with dinoprostone in 2 studies
| Studies (dt 5461) | Trials (dt 5461) | Recent Studies (post-2010) (dt 5461) | Studies (dinoprostone) | Trials (dinoprostone) | Recent Studies (post-2010) (dinoprostone) |
|---|---|---|---|---|---|
| 16 | 0 | 0 | 29,105 | 1,346 | 6,357 |
| Protein | Taxonomy | dt 5461 (IC50) | dinoprostone (IC50) |
|---|---|---|---|
| Prostaglandin E2 receptor EP1 subtype | Homo sapiens (human) | 0.0155 | |
| Prostaglandin E2 receptor EP4 subtype | Homo sapiens (human) | 0.0031 | |
| Prostaglandin E2 receptor EP4 subtype | Rattus norvegicus (Norway rat) | 0.0021 | |
| Prostaglandin E2 receptor EP3 subtype | Homo sapiens (human) | 0.002 | |
| Prostaglandin E2 receptor EP2 subtype | Homo sapiens (human) | 0.0087 | |
| Prostacyclin receptor | Homo sapiens (human) | 0.26 | |
| Prostaglandin E2 receptor EP2 subtype | Rattus norvegicus (Norway rat) | 0.0052 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akimoto, T; Jimbo, T; Tohgo, A | 1 |
| Akimoto, T; Jimbo, T; Joto, N; Kumazawa, E; Tohgo, A | 1 |
2 other study(ies) available for dt 5461 and dinoprostone
| Article | Year |
|---|---|
Effect of combined administration of a synthetic low-toxicity lipid A derivative, DT-5461a, and indomethacin in various experimental tumor models of colon 26 carcinoma in mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dinoprostone; Disaccharides; Drug Screening Assays, Antitumor; Indomethacin; Lipid A; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Peritoneal Neoplasms; Tumor Necrosis Factor-alpha | 1995 |
Antitumor effect of DT-5461, a lipid A derivative, against human tumor xenografts is mediated by intratumoral production of tumor necrosis factor and affected by host immunosuppressive factors in nude mice.
Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; Dinoprostone; Disaccharides; Drug Screening Assays, Antitumor; Fibrosarcoma; Humans; Lipid A; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |