dsp 4 has been researched along with clonidine in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (51.52) | 18.7374 |
| 1990's | 10 (30.30) | 18.2507 |
| 2000's | 5 (15.15) | 29.6817 |
| 2010's | 1 (3.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boyeson, MG; Callister, TR; Cavazos, JE | 1 |
| Daniels, WM; Jaffer, A; Russell, VA; Taljaard, JJ | 1 |
| Davis, KL; Haroutunian, V; Santucci, AC | 1 |
| Post, C; Wikberg, JE | 1 |
| Berridge, CW; Dunn, AJ | 2 |
| Campbell, IC; Ellison, DW | 1 |
| Reimann, W; Schneider, F | 1 |
| Buckett, WR; Heal, DJ; Prow, MR | 1 |
| Ball, GF; Balthazart, J | 1 |
| Daniels, WM; Jaffer, A; Russell, VA; Searson, A; Taljaard, JJ | 1 |
| Jaim-Etcheverry, G; Landa, ME; Rubio, MC | 1 |
| Abó, V; Barbeito, L; D'Angelo, L; Jantos, H; Monti, JM | 1 |
| Arbilla, S; Benkirane, S; Langer, SZ | 1 |
| Archer, T; Danysz, W; Minor, BG; Persson, ML; Post, C; Sundström, E | 1 |
| Swann, AC | 1 |
| Barbeito, L; Dajas, F; Fernández, C; Silveira, R | 1 |
| Fibiger, HC; Spyraki, C | 1 |
| Bickford, PC; Dunwiddie, TV; Mueller, AL; Zahniser, NR | 1 |
| Delini-Stula, A; Dooley, DJ; Mogilnicka, E; Truog, A; Waechter, F; Wood, J | 1 |
| Larsson, A; Lerner, U | 1 |
| Boissard, CG; Delini-Stula, A; Dooley, DJ; Mogilnicka, E | 1 |
| Buckett, WR; Butler, SA; Cheetham, SC; Gosden, J; Heal, DJ; Prow, MR | 1 |
| Buckett, WR; Butler, SA; Heal, DJ; Prow, MR | 1 |
| Cheng, CY; Lin, JC; Wang, JY; Wang, Y | 1 |
| Alessandrì, MG; Bassi, L; Corsini, GU; Fornai, F; Scalori, V; Torracca, MT | 1 |
| Blier, P; Haddjeri, N | 1 |
| Czyźewska-Szafran, H; Gozlinska, B | 1 |
| Harkin, A; Kelly, JP; Leonard, BE; Morris, K; O'Donnell, JM | 1 |
| Blier, P; Haddjeri, N; Lavoie, N | 1 |
| Avedian, T; Jentsch, JD; Kuperman, J; Marrs, W; Roth, RH | 1 |
| Archer, T; Fredriksson, A | 1 |
| Dawe, GS; Jay, TM; Lim, EP; Tan, CH | 1 |
33 other study(ies) available for dsp 4 and clonidine
| Article | Year |
|---|---|
Biochemical and behavioral effects of a sensorimotor cortex injury in rats pretreated with the noradrenergic neurotoxin DSP-4.
Topics: Adrenergic Agents; Afferent Pathways; Animals; Benzylamines; Brain Mapping; Cerebellum; Clonidine; Dominance, Cerebral; Hippocampus; Male; Motor Activity; Motor Cortex; Motor Skills; Nerve Fibers; Nerve Regeneration; Neuronal Plasticity; Norepinephrine; Phenoxybenzamine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Glutamate; Somatosensory Cortex | 1992 |
Effects of alpha 2- and beta-adrenoceptor agonists on growth hormone secretion following lesion of the noradrenergic system of the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Benzylamines; Clonidine; Dopamine; Frontal Lobe; Growth Hormone; Hippocampus; Hypothalamus; Isoproterenol; Male; Medial Forebrain Bundle; Norepinephrine; Oxidopamine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Serotonin | 1992 |
Pharmacological alleviation of combined cholinergic/noradrenergic lesion-induced memory deficits in rats.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Benzylamines; Cholinergic Agents; Cholinergic Fibers; Clonidine; Disease Models, Animal; Male; Memory; Organic Chemicals; Oxotremorine; Parasympathomimetics; Physostigmine; Rats; Rats, Inbred Strains; Substantia Innominata | 1991 |
Functional supersensitivity of antinociceptive spinal cord alpha 2-adrenoceptors, induced by depletion of endogenous noradrenaline, is associated with an enhanced sensitivity for guanine nucleotide regulation of 3H-clonidine binding.
Topics: Animals; Benzylamines; Clonidine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Male; Membranes; Mice; Nociceptors; Norepinephrine; Reaction Time; Receptors, Adrenergic, alpha; Spinal Cord | 1990 |
DSP-4-induced depletion of brain norepinephrine produces opposite effects on exploratory behavior 3 and 14 days after treatment.
Topics: Animals; Benzylamines; Brain Chemistry; Cerebral Cortex; Clonidine; Dioxanes; Exploratory Behavior; Hippocampus; Idazoxan; Male; Methoxyhydroxyphenylglycol; Mice; Norepinephrine; Phenylephrine; Prazosin; Restraint, Physical; Sympathomimetics | 1990 |
Studies on the role of alpha 2-adrenoceptors in the control of synaptosomal [3H]5-hydroxytryptamine release: effects of antidepressant drugs.
Topics: Animals; Antidepressive Agents; Benzylamines; Cerebral Cortex; Citalopram; Clonidine; Clorgyline; Desipramine; Hydroxyindoleacetic Acid; Male; Maprotiline; Nomifensine; Potassium; Propylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Synaptosomes; Yohimbine | 1986 |
Presynaptic alpha 2-adrenoceptors modulate the release of [3H]noradrenaline from rat spinal cord dorsal horn neurones.
Topics: Animals; Benzylamines; Calcium; Clonidine; Cocaine; Male; Neurons; Neurotoxins; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Spinal Cord; Tetrodotoxin; Tritium; Yohimbine; Zimeldine | 1989 |
Clonidine-induced hypoactivity and mydriasis in mice are respectively mediated via pre- and postsynaptic alpha 2-adrenoceptors in the brain.
Topics: Animals; Benzylamines; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid; Clonidine; Dose-Response Relationship, Drug; Electrochemistry; Injections, Intraperitoneal; Injections, Intraventricular; Male; Methamphetamine; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Motor Activity; Mydriatics; Neurotoxins; Receptors, Adrenergic, alpha; Synapses | 1989 |
Effects of the noradrenergic neurotoxin DSP-4 on luteinizing hormone levels, catecholamine concentrations, alpha 2-adrenergic receptor binding, and aromatase activity in the brain of the Japanese quail.
Topics: Adrenergic alpha-Agonists; Animals; Aromatase; Benzylamines; Brain; Catecholamines; Clonidine; Coturnix; Luteinizing Hormone; Male; Neurotoxins; Quail; Receptors, Adrenergic, alpha; Testosterone | 1989 |
The effect of partial noradrenergic denervation on corticosterone secretion in the rat.
Topics: Adrenergic Fibers; Animals; Benzylamines; Brain; Clonidine; Corticosterone; Isoproterenol; Male; Rats; Rats, Inbred Strains | 1989 |
Restraint-stress-induced changes in exploratory behavior appear to be mediated by norepinephrine-stimulated release of CRF.
Topics: Animals; Benzylamines; Biogenic Amines; Brain; Clonidine; Corticosterone; Corticotropin-Releasing Hormone; Exploratory Behavior; Male; Mice; Mice, Inbred Strains; Neurotoxins; Norepinephrine; Phenylephrine; Prazosin; Restraint, Physical; Stress, Physiological | 1989 |
[N-2-chloroethyl-N-ethyl-2-bromobenzylamine (DSP4) increases the liberation of 3H-noradrenaline produced by depolarization of the nerve ending].
Topics: Animals; Benzylamines; Cerebral Cortex; Clonidine; Female; Male; Nerve Endings; Norepinephrine; Phentolamine; Potassium; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Secretory Rate; Stimulation, Chemical; Vas Deferens; Yohimbine | 1988 |
Effect of DSP-4, a noradrenergic neurotoxin, on sleep and wakefulness and sensitivity to drugs acting on adrenergic receptors in the rat.
Topics: Animals; Benzylamines; Brain; Circadian Rhythm; Clenbuterol; Clonidine; Male; Methoxamine; Neurotoxins; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Sleep Stages; Sleep, REM; Wakefulness; Yohimbine | 1988 |
Supersensitivity of alpha 2-adrenoceptors modulating [3H]5-HT release after noradrenergic denervation with DSP4.
Topics: Adrenergic alpha-Antagonists; Amines; Animals; Benzylamines; Clonidine; Desipramine; Dioxanes; Electric Stimulation; Hippocampus; Idazoxan; Norepinephrine; Rats; Receptors, Adrenergic, alpha; Serotonin; Sympathectomy, Chemical | 1985 |
Increased antinociception by alpha-adrenoceptor drugs after spinal cord noradrenaline depletion.
Topics: Adrenergic alpha-Agonists; Analgesia; Animals; Benzylamines; Clonidine; Guanfacine; Guanidines; Hydroxydopamines; Injections, Spinal; Male; Morphine; Norepinephrine; Oxidopamine; Phenylacetates; Rats; Rats, Inbred Strains; Spinal Cord | 1987 |
(Na+,K+)-ATPase and noradrenergic regulation: effects of cardiac glycoside treatment and noradrenergic manipulations.
Topics: Animals; Benzylamines; Brain; Cardiac Glycosides; Clonidine; Desipramine; Digitoxin; Dihydroalprenolol; Kidney; Male; Methoxyhydroxyphenylglycol; Myocardium; Norepinephrine; Ouabain; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sodium-Potassium-Exchanging ATPase; Yohimbine | 1985 |
Evidences of a sympatho-adrenal dysfunction after lesion of the central noradrenergic pathways in rats.
Topics: Adrenal Medulla; Adrenergic Fibers; Animals; Benzylamines; Brain Diseases; Clonidine; Epinephrine; Male; Norepinephrine; Rats; Rats, Inbred Strains; Sympathetic Nervous System | 1986 |
Clonidine-induced sedation in rats: evidence for mediation by postsynaptic alpha 2-adrenoreceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Benzylamines; Clonidine; Hydroxydopamines; Hypnotics and Sedatives; Male; Neurotoxins; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synapses | 1982 |
Electrophysiological and biochemical sequelae of the destruction of hippocampal noradrenergic afferents by DSP4.
Topics: Afferent Pathways; Amines; Animals; Benzylamines; Clonidine; Dextroamphetamine; Hippocampus; Isoproterenol; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1983 |
Functional supersensitivity to adrenergic agonists in the rat after DSP-4, a selective noradrenergic neurotoxin.
Topics: Amines; Animals; Behavior, Animal; Benzylamines; Clenbuterol; Clonidine; Exploratory Behavior; Hemodynamics; Male; Microsomes, Liver; Myocardial Contraction; Neurotoxins; Norepinephrine; Rats; Receptors, Dopamine; Receptors, Serotonin; Sympathomimetics | 1983 |
Differential sensitivity of pinna reflex and esophageal temperature to clonidine in mice depleted of central noradrenaline by DSP-4.
Topics: Amines; Animals; Benzylamines; Body Temperature; Central Nervous System; Clonidine; Ear; Male; Mice; Neurotoxins; Norepinephrine; Reflex | 1984 |
Altered hindlimb extension in the rat after DSP-4: a useful marker of central noradrenergic depletion.
Topics: Amines; Animals; Behavior, Animal; Benzylamines; Brain; Clonidine; Drug Interactions; Hindlimb; Male; Neurotoxins; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1983 |
Receptor binding and functional evidence suggest that postsynaptic alpha 2-adrenoceptors in rat brain are of the alpha 2D subtype.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzylamines; Binding Sites; Binding, Competitive; Cerebral Cortex; Clonidine; Dioxanes; Dopamine; Idazoxan; Male; Mydriasis; Neurons; Norepinephrine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Serotonin; Zimeldine | 1995 |
Mediation of mydriasis in conscious rats by central postsynaptic alpha 2-adrenoceptors.
Topics: Adrenergic Agents; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Benzylamines; Biogenic Monoamines; Brain Chemistry; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; Male; Methamphetamine; Mydriatics; Neurons; Pupil; Rats; Receptors, Adrenergic, alpha-2; Receptors, Neurotransmitter | 1995 |
Enhanced antinociception of clonidine in spontaneously hypertensive rats involves a presynaptic noradrenergic mechanism.
Topics: Adrenergic Agents; Animals; Antihypertensive Agents; Benzylamines; Clonidine; Hypertension; In Vitro Techniques; Locus Coeruleus; Methamphetamine; Norepinephrine; Pain; Presynaptic Terminals; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1998 |
Noradrenergic modulation of methamphetamine-induced striatal dopamine depletion.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzylamines; Cell Count; Clonidine; Corpus Striatum; Dopamine; Dopamine Agents; Drug Combinations; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Norepinephrine; Rats; Rats, Sprague-Dawley; Yohimbine | 1998 |
Effect of neurokinin-I receptor antagonists on the function of 5-HT and noradrenaline neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Androstanes; Animals; Benzimidazoles; Benzylamines; Biphenyl Compounds; Clonidine; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intravenous; Locus Coeruleus; Lysergic Acid Diethylamide; Male; Neurokinin-1 Receptor Antagonists; Neurons; Norepinephrine; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
Systemic injection with DSP-4 decreases the clonidine hypotension in bicuculline-treated rats.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Benzylamines; Bicuculline; Biogenic Monoamines; Blood Pressure; Brain; Clonidine; Female; GABA Antagonists; Hypertension; Rats; Rats, Inbred WKY | 1999 |
Modulation of MK-801-induced behaviour by noradrenergic agents in mice.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Ataxia; Benzylamines; Clonidine; Desipramine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Frontal Lobe; Male; Mesencephalon; Mice; Morpholines; Motor Activity; Norepinephrine; Prazosin; Reboxetine; Stereotyped Behavior | 2001 |
Electrophysiological evidence for the tonic activation of 5-HT(1A) autoreceptors in the rat dorsal raphe nucleus.
Topics: Animals; Benzylamines; Clonidine; Dextroamphetamine; Dopamine Uptake Inhibitors; Electrophysiology; Lysergic Acid Diethylamide; Male; Neurons; Oxidopamine; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Sympathectomy, Chemical; Sympatholytics | 2004 |
Alpha-2 adrenoceptor activation inhibits phencyclidine-induced deficits of spatial working memory in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Benzylamines; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Guanfacine; Imidazoles; Male; Memory Disorders; Memory, Short-Term; Neurotransmitter Uptake Inhibitors; Phencyclidine; Rats; Rats, Long-Evans; Receptors, Adrenergic, alpha-2; Sex Factors; Spatial Behavior | 2005 |
Postnatal iron overload destroys NA-DA functional interactions.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Benzylamines; Clonidine; Corpus Striatum; Denervation; Dopamine; Dopamine Agents; Iron Overload; Levodopa; Male; Mice; Mice, Inbred C57BL; Motor Activity; MPTP Poisoning; Norepinephrine | 2007 |
Locus coeruleus stimulation and noradrenergic modulation of hippocampo-prefrontal cortex long-term potentiation.
Topics: Adrenergic Agents; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Benzylamines; Clonidine; Dopamine; Hippocampus; Idazoxan; Locus Coeruleus; Long-Term Potentiation; Male; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Serotonin | 2010 |