ds 4574 has been researched along with histamine in 4 studies
| Studies (ds 4574) | Trials (ds 4574) | Recent Studies (post-2010) (ds 4574) | Studies (histamine) | Trials (histamine) | Recent Studies (post-2010) (histamine) |
|---|---|---|---|---|---|
| 13 | 2 | 0 | 37,718 | 1,372 | 3,457 |
| Protein | Taxonomy | ds 4574 (IC50) | histamine (IC50) |
|---|---|---|---|
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | 0.1585 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.1585 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aibara, S; Iwamoto, T; Mori, M; Tsubokawa, M; Tsukada, W | 1 |
| Furuhama, K; Kawarabayashi, K; Tabuchi, Y | 1 |
| Furuhama, K; Tabuchi, Y | 1 |
| Kokue, E; Tabuchi, Y; Yamashika, Y | 1 |
4 other study(ies) available for ds 4574 and histamine
| Article | Year |
|---|---|
Antiallergic activity of 6-(2-cyclohexylethyl)-[1,3,4]thiadiazolo- [3,2-a]-1,2,3-triazolo-[4,5-d]pyrimidin-9(3H)-one (DS-4574) in rats.
Topics: Adrenalectomy; Anaphylaxis; Animals; Capillary Permeability; Histamine; Histamine Release; Hypersensitivity; Leukotriene Antagonists; Lung; Male; Passive Cutaneous Anaphylaxis; Peritoneal Cavity; Pyrimidines; Rats; Rats, Inbred Strains; Serotonin; Time Factors; Triazoles | 1992 |
Inhibitory effect of DS-4574, a peptidoleukotriene antagonist with mast cell stabilizing action, on compound 48/80-induced gastric mucosal lesions in rats.
Topics: Acetophenones; Administration, Oral; Animals; Cimetidine; Cromolyn Sodium; Gastric Mucosa; Histamine; Histamine Release; Injections, Intraperitoneal; Injections, Subcutaneous; Leukotriene Antagonists; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Pyrimidines; Rats; Rats, Sprague-Dawley; Tetrazoles; Triazoles | 1994 |
Inhibitory effect of DS-4574, a mast cell stabilizer with peptidoleukotriene receptor antagonism, on gastric acid secretion in rats.
Topics: Animals; Bucladesine; Carbachol; Fistula; Gastric Acid; H(+)-K(+)-Exchanging ATPase; Histamine; Leukotriene Antagonists; Male; Mast Cells; Pentagastrin; Pyrimidines; Rats; Rats, Sprague-Dawley; Stomach; Triazoles | 1994 |
Antisecretory effect of DS-4574, a mast cell stabilizer with peptidoleukotriene antagonism, on gastric acid secretion in the pig.
Topics: Adenosine Triphosphatases; Animals; Carbachol; Cation Transport Proteins; Female; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Injections, Intramuscular; Leukotriene Antagonists; Male; Pyrimidines; Swine; Swine, Miniature; Tetragastrin; Triazoles | 1994 |