doxylamine and pyridoxine

doxylamine has been researched along with pyridoxine in 205 studies

Research

Studies (205)

Timeframe	Studies, this research(%)	All Research%
pre-1990	107 (52.20)	18.7374
1990's	29 (14.15)	18.2507
2000's	19 (9.27)	29.6817
2010's	42 (20.49)	24.3611
2020's	8 (3.90)	2.80

Authors

Authors	Studies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Wheatley, D	1
Check, WA	1
Sheppard, S; Smithells, RW	2
Milkovich, L; van den Berg, BJ	1
Patterson, DC	1
Clarkson, SG; Glanvill, AP	1
Bayley, M; Valaske, MJ; Walsh, FM	1
McBride, WG	3
Berg, C; Bier, VM; Brannigan, VM	1
Saunders, EJ; Saunders, JA	1
Giuffrè, R; Liccardo, G; Pastore, FS; Spallone, A; Vagnozzi, R	1
Munro, CD	1
Newman, SA	1
Skolnick, A	1
Scialli, AR	1
Bailey, JR; Holder, CL; Lipe, GW; Slikker, W; Young, JF	1
Denton, R; Hendrickx, AG; Holder, CL; Prahalada, S; Rowland, JM; Slikker, W; Young, JF	1
Arthur, DC; Benjamin, D; Buckley, JD; Daigle, AE; Hammond, GD; Robison, LL; Wells, R	1
Klebanoff, MA; Shiono, PH	1
Leathem, AM	1
Brent, RL	3
Kiley, VA; Lazerson, J	1
Einarson, TR; Koren, G; Leeder, JS	1
Garrison, JM; Jick, SS	1
Broughton, D; Griffin, MR; Hoffman, AD; Jedd, MB; Kaufman, B; Melton, LJ; O'Brien, PC	1
Kimmel, CA; Marr, MC; Price, CJ; Tyl, RW	1
Golbus, MS; Goldberg, JD	1
Elbourne, D; Mutch, L	1
Walters, WA	1
Correy, JF; Newman, NM	3
Melnick, M	1
Hunter-Mitchell, J; Jick, H; Porter, JB; Walker, AM	1
Batagol, R; Sheffield, LJ	1
Orme, ML	1
Kolata, G	2
Aselton, P; Hunter, JR; Jick, H; Milunsky, A; Stergachis, A	1
Rothman, KJ; Zierler, S	1
Danks, DM	1
Campbell, H; Dauncey, M; Elbourne, D; Mutch, L; Samphier, M	1
Hocking, B	1
Cukierski, M; Hendrickx, AG; Janos, G; Prahalada, S; Rowland, J	1
Booher, S; Cukierski, M; Hendrickx, AG; Janos, G; Nyland, T; Prahalada, S	1
Greene, C; Shapira, E; Wilson, A	1
Birch, JM; Cartwright, RA; Hartley, AL; Hopton, PA; Johnston, HE; Mann, JR; McKinney, PA; Stiller, CA; Waterhouse, JA	1
Shearman, RP; Smith, ID	1
Clarke, M; Clayton, DG	1
Hall, JB	1
Berg, A; Bracken, MB	1
Mitchell, AA; Shapiro, S	1
Cavanagh, N; Hughes, DT	1
Deitch, R	1
Kalter, H; Warkany, J	1
Holmes, LB	1
Patterson, SP	1
Hill, LM; Kleinberg, F	1
Cordero, JF; Oakley, GP	1
Aselton, P; Chentow, SJ; Hunter, JR; Jick, H; Perera, DR; Rothman, KJ	1
Grodofsky, MP; Wilmott, RW	1
Maling, TJ	1
Leeder, JS; MacLeod, SM; Spielberg, SP	1
Hays, DP	1
Brushwood, DB	2
Louik, C; Mitchell, AA; Rosenberg, L; Schwingl, PJ; Shapiro, S	1
Aselton, PJ; Jick, H	1
Altman, PM	1
Elliott, J; Forrest, J; Kricker, A; McCredie, J	1
Davis, JM	1
Smith, R	1
Griffiths, K; Harron, DW; Shanks, RG	2
Crombie, DL; Fleming, DM; Knox, JD	1
Glück, E; Koller, S; Michaelis, H; Michaelis, J	1
Brent, RR	1
Brown, A	1
Leal, J	1
Huff, PS	1
Smith, RJ	1
Alpert, JJ; Day, N; Dooling, E; Flowerdew, G; Hingson, R; Kayne, H; Morelock, S; Zuckerman, B	1
Gart, JJ; Thomas, DG	1
David, TJ	1
Bury, RG; Donaldson, GL	1
Bracken, MB; Eskenazi, B	1
Cordero, JF; Greenberg, F; James, LM; Oakley, GP	1
Mitchell, AA; Rosenberg, L; Shapiro, S; Slone, D	1
Colley, DP; Gibson, GT; Hartshorne, JM; McMichael, AJ	1
Kolata, GB	1
Korcok, M	1
Paigen, B	1
Pearson, RD	1
Dubowitz, V; Muntoni, F; Philpot, J; Skellett, S	1
Barinaga, M	1
Kutcher, JS; Lamm, SH; Linn, S; McKeigue, PM	1
Appelbaum, PS	1
Bertin, JE; Henifin, MS	1
Green, MD	1
Mervis, J	1
Marwick, C	1
Marshall, E	1
Bailey, B; Einarson, A; Koren, G	2
Linehan, SJ	1
Bracken, MB	1
Ito, S; Koren, G; Pastuszak, A	1
Sanders, J	1
Crane, M	1
Jackson, KA	1
Argekar, AP; Sawant, JG	1
Koren, G; Magee, LA; Maltepe, C; Mazzotta, P; Navioz, Y	1
Atanackovic, G; Bishai, R; Koren, G; Levichek, Z; Magee, LA; Mazzotta, P; Pole, M	1
Atanackovic, G; Koren, G; Moretti, ME; Navioz, Y	1
Strong, TH	1
Brent, R	2
Louik, C; Mitchell, AA	1
Engle, A; Firth, J; Kutcher, JS; Lamm, SH	1
NULSEN, RO	1
TOWNE, JE	1
FAHRENBACH, DM; GEIGER, CJ; HEALEY, FJ	1
Boskovic, R; Einarson, A; Koren, G; Maltepe, C; Wolpin, J	1
Brickley, P	1
Boskovic, R; Danieliewska-Nikiel, B; Koren, G; Navioz, Y; Rudic, N	1
Koren, G; Maltepe, C	2
Babineau, D; Buckley, DN; Cook, DJ; Reeve, BK; Scholes, LC	1
McKay, BJ; Tucker, WA	1
Garcia-Bournissen, F; Koren, G; Staroselsky, A	1
Barrera, M; Feldman, BM; Knittel-Keren, D; Koren, G; Nulman, I; Rovet, J	1
Koren, G; Nulman, I	1
Caritis, SN; Clark, S; Hankins, GD; Koren, G; Mattison, DR; Miodovnik, M; Umans, JG	2
Niebyl, JR	1
Garcia-Bournissen, F; Gill, SK; Koren, G	1
Omar, SZ; Tan, PC	1
Healy, D; Persaud, N	1
Caritis, S; Chiossi, G; Clark, S; Costantine, MM; Hankins, GD; Koren, G; Matok, I; Miodovnik, M; Umans, JG	1
Caritis, S; Clark, S; Hankins, G; Koren, G; Matok, I; Miodovnik, M; Umans, J	1
Ashkenazi-Hoffnung, L; Klinger, G; Merlob, P; Stahl, B	1
Koren, G	2
Caritis, S; Clark, S; Feghali, MN; Hankins, G; Koren, G; Matok, I; Mattison, DR; Miodovnik, M; Nordeng, H; Umans, J	1
Gill, SK; Koren, G; Macleod, S; Vranderick, M	1
Howland, RH	1
Briggs, GG; Niebyl, JR	1
Hansen, KA	1
Koren, G; Madjunkova, S; Maltepe, C	2
Hearns-Stokes, R; Joffe, HV; Slaughter, SR; van der Vlugt, T	1
Chin, J; Persaud, N; Walker, M	1
Caritis, S; Clark, S; Hankins, G; Koren, G; Matok, I; Mattison, DR; Miodovnik, M; Umans, JG	1
Capp, SM; Carstairs, SD; Oliveira, LG; Riffenburgh, RH; You, WB	1
Clark, SM; Dutta, E; Hankins, GD	1
Cunningham, K	1
Capp, S; Oliveira, L	1
Koren, G; Maltepe, C; Pope, E	1
Caritis, SN; Clark, S; Hankins, GD; Koren, G; Matok, I; Mattison, DR; Miodovnik, M; Umans, JG	2
Beyer, F; Bradley, J; Bryant, A; McParlin, C; Moloney, E; Muirhead, CR; Nelson-Piercy, C; Newbury-Birch, D; Norman, J; O'Donnell, A; Robson, SC; Shaw, C; Simpson, E; Swallow, B; Vale, L; Yates, L	1
Persaud, N; Zhang, R	1
Dyer, O	1
Kvern, B; Pimlott, N; Woollard, R	1
El-Emam, K; Meaney, C; Moineddin, R; Persaud, N; Thorpe, K	1
Al-Degs, Y; Alin, A; Gergov, G; Kassarova, M; Katsarov, P; Pilicheva, B; Simeonov, V	1
Gergov, G; Kassarova, M; Katsarov, P; Pilicheva, B; Uzunova, Y	1
Byland, E; Canupp, K; Dunlap, J; Mospan, C; Mospan, G; Whitaker, WB; Xiong, L	1
Bérard, A; Bernatsky, S; Gorgui, J; Sheehy, O; Soares de Moura, C; Zhao, JP	1
Fejzo, MS; Grooten, IJ; Mullin, PM; Painter, RC; Roseboom, TJ; Sridharan, K; Trovik, J; Vikanes, Å	1
Kleinhans, NM; MacDuffie, KE; Stout, K; Wilfond, BS	1
Biffi, A; Cetin, I; Corrao, G; Filippelli, A; Locatelli, A; Rea, F	1
Aboud, HM; Ali, AA; Hegazy, AM; Sadek, AA; Salem, HF	1
Alcocer, C; Gergic, E; Hoarau, D; Iraola, M; Perez de la Cruz, MA; Regidor, PA; Rom, E	1
Mangrella, M; Saz-Leal, P; Urso, K; Zamorano Dominguez, L	1
Alcocer, C; Regidor, PA; Rom, E	1
Frías, J; García-Aguilar, E; Guerra, P; Nebot-Troyano, J; Roca-Juanes, R; Saura-Valls, M; Saz-Leal, P; Urso, K; Vilchez, T; Zamorano-Domínguez, L	1
An, CM; Cao, YJ; Chen, XY; Cong, J; Cui, YM; Feng, YH; Gao, JS; Hu, YH; Li, J; Li, L; Liu, JP; Liu, L; Liu, YX; Liu, ZL; Liu, ZS; Lu, ZL; Ma, HL; Mol, BWJ; Ng, EHY; Painter, RC; Qi, X; Qin, HC; Wang, CC; Wang, Y; Wang, YX; Wu, Q; Wu, XK; Yan, Y; Yang, XM; Yu, L; Zhang, B; Zhou, LL	1

Reviews

23 review(s) available for doxylamine and pyridoxine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug therapy in pregnancy: the lessons of diethylstilbestrol, thalidomide, and bendectin. Health care for women international, 1990, Volume: 11, Issue:4 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Diethylstilbestrol; Doxylamine; Drug Combinations; Drug Industry; Female; Humans; Infant, Newborn; Physician-Patient Relations; Pregnancy; Public Opinion; Pyridoxine; Thalidomide	1990
Safety and efficacy of antiemetics used to treat nausea and vomiting in pregnancy. Clinical pharmacy, 1986, Volume: 5, Issue:8 Topics: Antiemetics; Antipsychotic Agents; Dicyclomine; Diphenhydramine; Doxylamine; Drug Combinations; Female; Humans; Meclizine; Metoclopramide; Nausea; Phenothiazines; Pregnancy; Pregnancy Complications; Pyridoxine; Risk; Teratogens; Vomiting	1986
The creation of therapeutic orphans--or, what have we learnt from the Debendox fiasco? The Medical journal of Australia, 1985, Aug-19, Volume: 143, Issue:4 Topics: Abnormalities, Drug-Induced; Animals; Antiemetics; Australia; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Combinations; Female; Haplorhini; Humans; Infant, Newborn; Macaca fascicularis; Pregnancy; Pyridines; Pyridoxine; Rabbits; Random Allocation; Rats; Risk; Teratogens; United States; United States Food and Drug Administration	1985
Congenital malformations (second of two parts). The New England journal of medicine, 1983, Mar-03, Volume: 308, Issue:9 Topics: Abnormalities, Drug-Induced; Air Pollutants, Occupational; Alcohol Drinking; Anesthetics; Anticoagulants; Anticonvulsants; Caffeine; Dicyclomine; Doxylamine; Drug Combinations; Estrogens; Female; Humans; Infant, Newborn; Pyridoxine; Smoking; Spermatocidal Agents; Substance-Related Disorders	1983
Teratogen update: bendectin. Teratology, 1983, Volume: 27, Issue:2 Topics: Abnormalities, Drug-Induced; Animals; Dicyclomine; Doxylamine; Drug Combinations; Drug Utilization; Female; Fetus; Health Education; Humans; Pregnancy; Pyridines; Pyridoxine; Rabbits; Rats; Teratogens	1983
Effects of drugs and chemicals on the fetus and newborn (1). Mayo Clinic proceedings, 1984, Volume: 59, Issue:10 Topics: Abnormalities, Drug-Induced; Animals; Antiemetics; Behavior; Caffeine; Dicyclomine; Doxylamine; Drug Combinations; Embryo, Mammalian; Female; Ferrous Compounds; Fetus; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Nervous System; Nonprescription Drugs; Oocytes; Pregnancy; Prenatal Exposure Delayed Effects; Pyridoxine; Reproduction; Spermatozoa; Vitamins	1984
Drug exposure during pregnancy: some epidemiologic considerations. Clinical obstetrics and gynecology, 1983, Volume: 26, Issue:2 Topics: Abnormalities, Drug-Induced; Benzodiazepines; Caffeine; Dicyclomine; Doxylamine; Drug Combinations; Epidemiologic Methods; Female; Humans; Hydantoins; Immunosuppressive Agents; Lithium; Lithium Carbonate; Phenothiazines; Pregnancy; Pyridoxine; Registries; Risk; Rubella Vaccine; Solvents; Spermatocidal Agents; Trimethadione; Valproic Acid	1983
Safety of drug therapy for nausea and vomiting of pregnancy. The Journal of family practice, 1980, Volume: 11, Issue:6 Topics: Abnormalities, Drug-Induced; Antiemetics; Child; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Nausea; Pregnancy; Pregnancy Complications; Prospective Studies; Pyridoxine; Retrospective Studies; Teratogens; Vomiting	1980
Bendectin and birth defects: I. A meta-analysis of the epidemiologic studies. Teratology, 1994, Volume: 50, Issue:1 Topics: Abnormalities, Drug-Induced; Antiemetics; Case-Control Studies; Cohort Studies; Dicyclomine; Doxylamine; Drug Combinations; Europe; Female; Humans; Odds Ratio; Pregnancy; Pregnancy Trimester, First; Pyridoxine; United States	1994
Drugs in pregnancy. The New England journal of medicine, 1998, Apr-16, Volume: 338, Issue:16 Topics: Abnormalities, Drug-Induced; Animals; Counseling; Dicyclomine; Doxylamine; Drug Combinations; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Epidemiologic Studies; Female; Fetus; Humans; Infant, Newborn; Information Services; Isotretinoin; Pharmaceutical Preparations; Pregnancy; Pregnancy Complications; Pyridoxine; Risk; Teratogens; Thalidomide	1998
Critical appraisal of drug therapy for nausea and vomiting of pregnancy: II. Efficacy and safety of diclectin (doxylamine-B6). The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique, 2000,Autumn, Volume: 7, Issue:3 Topics: Antiemetics; Doxylamine; Female; Humans; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Randomized Controlled Trials as Topic; Vitamin B 6 Deficiency	2000
Alternative therapies of morning sickness. Clinical obstetrics and gynecology, 2001, Volume: 44, Issue:4 Topics: Acupressure; Antiemetics; Complementary Therapies; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Hyperemesis Gravidarum; Nausea; Pregnancy; Pyridoxine; Safety; Vomiting; Zingiber officinale	2001
Medical, social, and legal implications of treating nausea and vomiting of pregnancy. American journal of obstetrics and gynecology, 2002, Volume: 186, Issue:5 Suppl Un Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Vomiting	2002
Clinical practice. Nausea and vomiting in pregnancy. The New England journal of medicine, 2010, Oct-14, Volume: 363, Issue:16 Topics: Adult; Chorionic Gonadotropin; Complementary Therapies; Diagnosis, Differential; Dicyclomine; Doxylamine; Drug Combinations; Female; Histamine Antagonists; Humans; Hyperemesis Gravidarum; Morning Sickness; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications; Pyridoxine; Weight Loss	2010
Contemporary approaches to hyperemesis during pregnancy. Current opinion in obstetrics & gynecology, 2011, Volume: 23, Issue:2 Topics: Adrenal Cortex Hormones; Antiemetics; Diet; Doxylamine; Female; Humans; Hyperemesis Gravidarum; Obstetrics; Ondansetron; Plant Extracts; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pyridoxine; Zingiber officinale	2011
The pharmacologic management of nausea and vomiting of pregnancy. The Journal of family practice, 2014, Volume: 63, Issue:2 Suppl Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Histamine H1 Antagonists; Humans; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Vomiting	2014
The delayed-release combination of doxylamine and pyridoxine (Diclegis®/Diclectin ®) for the treatment of nausea and vomiting of pregnancy. Paediatric drugs, 2014, Volume: 16, Issue:3 Topics: Antiemetics; Delayed-Action Preparations; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Treatment Outcome; Vomiting	2014
The outpatient management and special considerations of nausea and vomiting in pregnancy. Seminars in perinatology, 2014, Volume: 38, Issue:8 Topics: Ambulatory Care; Antiemetics; Diet Therapy; Doxylamine; Female; Fluid Therapy; Gastroesophageal Reflux; Histamine H1 Antagonists; Humans; Hyperemesis Gravidarum; Metoclopramide; Morning Sickness; Ondansetron; Pregnancy; Promethazine; Pyridoxine; Severity of Illness Index; Vitamin B Complex	2014
Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review. JAMA, 2016, 10-04, Volume: 316, Issue:13 Topics: Acupuncture; Adrenal Cortex Hormones; Antiemetics; Doxylamine; Female; Histamine Antagonists; Humans; Hyperemesis Gravidarum; Nausea; Ondansetron; Phytotherapy; Pregnancy; Pregnancy Complications; Psychotherapy; Pyridoxine; Randomized Controlled Trials as Topic; Vitamin B Complex; Vomiting; Zingiber officinale	2016
Doxylamine/pyridoxine for nausea and vomiting in pregnancy. Drug and therapeutics bulletin, 2019, Volume: 57, Issue:3 Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Nausea; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications; Pyridoxine; Vomiting	2019
Nausea and vomiting of pregnancy and hyperemesis gravidarum. Nature reviews. Disease primers, 2019, 09-12, Volume: 5, Issue:1 Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Growth Differentiation Factor 15; Humans; Hyperemesis Gravidarum; Mass Screening; Nausea; Pregnancy; Pyridoxine	2019
Misleading meta-analyses of observational studies may generate unjustified alarms: The case of medications for nausea and vomiting in pregnancy. Pharmacological research, 2021, Volume: 163 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Nausea; Observational Studies as Topic; Odds Ratio; Pregnancy; Pyridoxine; Scientific Experimental Error; Uncertainty; Vomiting	2021

Trials

23 trial(s) available for doxylamine and pyridoxine

Article	Year
Treatment of pregnancy sickness. British journal of obstetrics and gynaecology, 1977, Volume: 84, Issue:6 Topics: Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dicyclomine; Double-Blind Method; Doxylamine; Female; Humans; Nausea; Placebos; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Pyridoxine; Vomiting	1977
An evaluation of the teratogenicity of certain antinauseant drugs. American journal of obstetrics and gynecology, 1976, May-15, Volume: 125, Issue:2 Topics: Abnormalities, Drug-Induced; Antiemetics; Clinical Trials as Topic; Cyclizine; Dicyclomine; Doxylamine; Drug Combinations; Drug Evaluation; Female; Fetal Death; Humans; Hyperemesis Gravidarum; Meclizine; Patient Compliance; Phenothiazines; Pregnancy; Prochlorperazine; Prospective Studies; Pyridoxine; Teratogens	1976
Maternal drug use and risk of childhood nonlymphoblastic leukemia among offspring. An epidemiologic investigation implicating marijuana (a report from the Childrens Cancer Study Group). Cancer, 1989, May-15, Volume: 63, Issue:10 Topics: Adolescent; Age Factors; Antiemetics; Child; Child, Preschool; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Marijuana Smoking; Multicenter Studies as Topic; Pharmaceutical Preparations; Postpartum Period; Pregnancy; Prenatal Exposure Delayed Effects; Pyridoxine	1989
The creation of therapeutic orphans--or, what have we learnt from the Debendox fiasco? The Medical journal of Australia, 1985, Aug-19, Volume: 143, Issue:4 Topics: Abnormalities, Drug-Induced; Animals; Antiemetics; Australia; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Combinations; Female; Haplorhini; Humans; Infant, Newborn; Macaca fascicularis; Pregnancy; Pyridines; Pyridoxine; Rabbits; Random Allocation; Rats; Risk; Teratogens; United States; United States Food and Drug Administration	1985
Studies support Bendectin safety claim. Science (New York, N.Y.), 1981, Jun-26, Volume: 212, Issue:4502 Topics: Antiemetics; Clinical Trials as Topic; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant Mortality; Infant, Newborn; Pregnancy; Pregnancy Complications; Pyridines; Pyridoxine	1981
FDA to reexamine bendectin data. Science (New York, N.Y.), 1982, Jul-23, Volume: 217, Issue:4557 Topics: Abnormalities, Drug-Induced; Animals; Clinical Trials as Topic; Dicyclomine; Doxylamine; Drug Combinations; Female; Heart Septal Defects, Ventricular; Hernia, Diaphragmatic; Humans; Macaca; Pregnancy; Pyridines; Pyridoxine; Rats; United States; United States Food and Drug Administration	1982
Is lack of morning sickness teratogenic? A prospective controlled study. Birth defects research. Part A, Clinical and molecular teratology, 2004, Volume: 70, Issue:8 Topics: Adult; Antiemetics; Congenital Abnormalities; Doxylamine; Female; Genetic Counseling; Humans; Maternal Age; Morning Sickness; Pregnancy; Pregnancy Outcome; Pyridoxine	2004
Pre-emptive therapy for severe nausea and vomiting of pregnancy and hyperemesis gravidarum. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2004, Volume: 24, Issue:5 Topics: Adult; Antiemetics; Dicyclomine; Doxylamine; Drug Administration Schedule; Drug Combinations; Female; Fluid Therapy; Humans; Hyperemesis Gravidarum; Ondansetron; Pregnancy; Prenatal Care; Prospective Studies; Pyridoxine; Severity of Illness Index; Treatment Outcome; Vitamin B 6	2004
Prophylactic Diclectin reduces the incidence of postoperative vomiting. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2005, Volume: 52, Issue:1 Topics: Adult; Ambulatory Surgical Procedures; Antiemetics; Dicyclomine; Double-Blind Method; Doxylamine; Drug Combinations; Female; Humans; Laparoscopy; Postoperative Nausea and Vomiting; Pyridoxine; Sample Size; Sterilization, Tubal; Treatment Outcome	2005
Pharmacokinetic comparison of a delayed-release combination of doxylamine succinate and pyridoxine hydrocholoride (Diclectin) and oral solutions of these drugs in healthy women of childbearing age. The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique, 2009,Fall, Volume: 16, Issue:3 Topics: Adult; Antiemetics; Area Under Curve; Biological Availability; Cross-Over Studies; Delayed-Action Preparations; Doxylamine; Drug Combinations; Female; Humans; Pregnancy; Pyridoxal; Pyridoxal Phosphate; Pyridoxine; Solutions; Tablets	2009
Effectiveness of delayed-release doxylamine and pyridoxine for nausea and vomiting of pregnancy: a randomized placebo controlled trial. American journal of obstetrics and gynecology, 2010, Volume: 203, Issue:6 Topics: Adult; Delayed-Action Preparations; Dicyclomine; Dose-Response Relationship, Drug; Double-Blind Method; Doxylamine; Drug Administration Schedule; Drug Combinations; Female; Follow-Up Studies; Gestational Age; Humans; Morning Sickness; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Quality of Life; Reference Values; Severity of Illness Index; Treatment Outcome; Vomiting; Young Adult	2010
Determinants of adherence to delayed-release doxylamine and pyridoxine in patients with nausea and vomiting of pregnancy. Therapeutic drug monitoring, 2012, Volume: 34, Issue:5 Topics: Adult; Antiemetics; Cohort Studies; Delayed-Action Preparations; Dicyclomine; Double-Blind Method; Doxylamine; Drug Combinations; Female; Humans; Medication Adherence; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Vomiting	2012
Comparing the pharmacokinetics of doxylamine/pyridoxine delayed-release combination in nonpregnant women of reproductive age and women in the first trimester of pregnancy. Journal of clinical pharmacology, 2013, Volume: 53, Issue:3 Topics: Adolescent; Adult; Antiemetics; Delayed-Action Preparations; Dicyclomine; Double-Blind Method; Doxylamine; Drug Combinations; Female; Humans; Middle Aged; Pregnancy; Pregnancy Trimester, First; Pyridoxine; Young Adult	2013
Sex differences in the pharmacokinetics and bioequivalence of the delayed-release combination of doxylamine succinate-pyridoxine hydrochloride; implications for pharmacotherapy in pregnancy. Journal of clinical pharmacology, 2013, Volume: 53, Issue:12 Topics: Adult; Antiemetics; Delayed-Action Preparations; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Male; Pregnancy; Pyridoxine; Sex Characteristics; Therapeutic Equivalency	2013
Studying the antiemetic effect of vitamin B6 for morning sickness: pyridoxine and pyridoxal are prodrugs. Journal of clinical pharmacology, 2014, Volume: 54, Issue:12 Topics: Antiemetics; Delayed-Action Preparations; Dicyclomine; Double-Blind Method; Doxylamine; Drug Combinations; Female; Humans; Morning Sickness; Pregnancy; Prodrugs; Pyridoxal; Pyridoxal Phosphate; Pyridoxine	2014
Ondansetron compared with doxylamine and pyridoxine for treatment of nausea in pregnancy: a randomized controlled trial. Obstetrics and gynecology, 2014, Volume: 124, Issue:4 Topics: Adult; Antiemetics; Double-Blind Method; Doxylamine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hyperemesis Gravidarum; Morning Sickness; Nausea; Ondansetron; Patient Satisfaction; Pregnancy; Pyridoxine; Risk Assessment; Severity of Illness Index; Treatment Outcome; Vomiting; Young Adult	2014
Comparing pyridoxine and doxylamine succinate-pyridoxine HCl for nausea and vomiting of pregnancy: A matched, controlled cohort study. Journal of clinical pharmacology, 2015, Volume: 55, Issue:7 Topics: Adult; Antiemetics; Cohort Studies; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Morning Sickness; Pregnancy; Prospective Studies; Pyridoxine; Severity of Illness Index; Treatment Outcome	2015
Maternal safety of the delayed-release doxylamine and pyridoxine combination for nausea and vomiting of pregnancy; a randomized placebo controlled trial. BMC pregnancy and childbirth, 2015, Mar-18, Volume: 15 Topics: Adult; Antiemetics; Delayed-Action Preparations; Dicyclomine; Double-Blind Method; Doxylamine; Drug Combinations; Drug Monitoring; Female; Histamine H1 Antagonists; Humans; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Treatment Outcome; Vitamin B Complex; Vomiting	2015
Effectiveness of doxylamine-pyridoxine for morning sickness. American journal of obstetrics and gynecology, 2016, Volume: 214, Issue:5 Topics: Delayed-Action Preparations; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Morning Sickness; Pregnancy; Pyridoxine	2016
Demonstration of early efficacy results of the delayed-release combination of doxylamine-pyridoxine for the treatment of nausea and vomiting of pregnancy. BMC pregnancy and childbirth, 2016, 11-24, Volume: 16, Issue:1 Topics: Antiemetics; Delayed-Action Preparations; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Morning Sickness; Pregnancy; Pyridoxine; Time Factors	2016
8-Way Randomized Controlled Trial of Doxylamine, Pyridoxine and Dicyclomine for Nausea and Vomiting during Pregnancy: Restoration of Unpublished Information. PloS one, 2017, Volume: 12, Issue:1 Topics: Cooperative Behavior; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Nausea; Physicians; Placebos; Pregnancy; Pregnancy Complications; Publication Bias; Publications; Pyridoxine; Research Report; Risk; Vomiting	2017
Doxylamine-pyridoxine for nausea and vomiting of pregnancy randomized placebo controlled trial: Prespecified analyses and reanalysis. PloS one, 2018, Volume: 13, Issue:1 Topics: Doxylamine; Drug Therapy, Combination; Female; Humans; Morning Sickness; Placebos; Pregnancy; Pyridoxine	2018
Acupuncture and Doxylamine-Pyridoxine for Nausea and Vomiting in Pregnancy : A Randomized, Controlled, 2 Annals of internal medicine, 2023, Volume: 176, Issue:7 Topics: Acupuncture Therapy; Antiemetics; Child; Doxylamine; Female; Humans; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Quality of Life; Vomiting	2023

Other Studies

160 other study(ies) available for doxylamine and pyridoxine

Article	Year
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
CDC study: no evidence for teratogenicity of Bendectin. JAMA, 1979, Dec-07, Volume: 242, Issue:23 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Heart Defects, Congenital; Humans; Hyperemesis Gravidarum; Nausea; Pregnancy; Pyridines; Pyridoxine; Vomiting	1979
Teratogenicity testing in humans: a method demonstrating safety of bendectin. Teratology, 1978, Volume: 17, Issue:1 Topics: Abnormalities, Drug-Induced; Animals; Antiemetics; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Evaluation; Embryo, Mammalian; Embryo, Nonmammalian; Female; Fetus; Pregnancy; Pregnancy Complications; Pyridines; Pyridoxine; Teratogens	1978
Fetal malformation after Debendox treatment in early pregnancy. British medical journal, 1978, Apr-22, Volume: 1, Issue:6119 Topics: Abnormalities, Drug-Induced; Antiemetics; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Limb Deformities, Congenital; Pregnancy; Pyridines; Pyridoxine; Time Factors	1978
Congenital deformities associated with Benedectin. Canadian Medical Association journal, 1977, Jun-18, Volume: 116, Issue:12 Topics: Abnormalities, Drug-Induced; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Pregnancy; Pyridines; Pyridoxine	1977
Debendox overdosage in children. British medical journal, 1977, Aug-13, Volume: 2, Issue:6084 Topics: Child, Preschool; Delayed-Action Preparations; Dicyclomine; Doxylamine; Drug Combinations; Humans; Male; Pyridoxine	1977
Congenital deformities associated with Bendectin. Canadian Medical Association journal, 1977, Oct-08, Volume: 117, Issue:7 Topics: Abnormalities, Drug-Induced; Adult; Cleft Lip; Cleft Palate; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Nausea; Pregnancy; Pregnancy Complications; Pyridines; Pyridoxine	1977
Fatal overdose from Bendectin. Clinical pediatrics, 1975, Volume: 14, Issue:5 Topics: Accidents, Home; Autopsy; Child, Preschool; Chromatography, Gas; Cyclohexanecarboxylic Acids; Cyclohexanes; Delayed-Action Preparations; Diethylamines; Doxylamine; Drug Combinations; Humans; Male; Pulmonary Atelectasis; Pyridines; Pyridoxine; Spectrophotometry, Ultraviolet	1975
Prescription drugs in the first trimester and congenital malformations. The Australian & New Zealand journal of obstetrics & gynaecology, 1992, Volume: 32, Issue:4 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Ectromelia; Female; Humans; Infant, Newborn; Pregnancy; Pyridoxine	1992
Risk, statistical inference, and the law of evidence: the use of epidemiological data in toxic tort cases. Risk analysis : an official publication of the Society for Risk Analysis, 1992, Volume: 12, Issue:3 Topics: Abnormalities, Drug-Induced; Antiemetics; Confidence Intervals; Data Interpretation, Statistical; Dicyclomine; Doxylamine; Drug Combinations; Epidemiology; Female; Humans; Infant, Newborn; Pregnancy; Pyridoxine; Risk; Toxicology; United States	1992
Potential risk factors for brain tumors in children. An analysis of 200 cases. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 1990, Volume: 6, Issue:1 Topics: Adolescent; Brain Neoplasms; Child; Dicyclomine; Doxylamine; Drug Combinations; Female; Glioma; Humans; Pregnancy; Pregnancy Complications; Pyridoxine; Risk Factors	1990
Drugs in pregnancy. Australian College of Midwives Incorporated journal, 1990, Volume: 2, Issue:4 Topics: Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Hyperemesis Gravidarum; Pregnancy; Pyridoxine	1990
Bendectin--birth defects controversy. JAMA, 1990, Aug-01, Volume: 264, Issue:5 Topics: Abnormalities, Drug-Induced; Animals; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Extremities; Female; Humans; Pregnancy; Pyridines; Pyridoxine	1990
Key witness against morning sickness drug faces scientific fraud charges. JAMA, 1990, Mar-16, Volume: 263, Issue:11 Topics: Animals; Antiemetics; Australia; Biomedical Research; Dicyclomine; Doxylamine; Drug Combinations; Female; History, 20th Century; Humans; Pregnancy; Pregnancy Complications; Pregnant Women; Pyridoxine; Rabbits; Scientific Misconduct; Scopolamine	1990
Bendectin, science, and the law. Reproductive toxicology (Elmsford, N.Y.), 1989, Volume: 3, Issue:3 Topics: Dicyclomine; Doxylamine; Drug Combinations; Humans; Legislation, Drug; Pyridoxine; Teratogens; United States	1989
Pharmacokinetics of doxylamine, a component of Bendectin, in the rhesus monkey. Reproductive toxicology (Elmsford, N.Y.), 1989, Volume: 3, Issue:3 Topics: Animals; Chromatography, Gas; Chromatography, High Pressure Liquid; Dicyclomine; Doxylamine; Drug Combinations; Female; Half-Life; Intestinal Absorption; Macaca mulatta; Models, Biological; Pyridoxine	1989
Pharmacokinetics of doxylamine given as Bendectin in the pregnant monkey and baboon. Reproductive toxicology (Elmsford, N.Y.), 1989, Volume: 3, Issue:3 Topics: Animals; Chromatography, Gas; Dicyclomine; Doxylamine; Drug Combinations; Female; Half-Life; Macaca fascicularis; Macaca mulatta; Papio; Pregnancy; Pregnancy, Animal; Pyridoxine	1989
Bendectin and human congenital malformations. Teratology, 1989, Volume: 40, Issue:2 Topics: Abnormalities, Drug-Induced; Central Nervous System; Dicyclomine; Digestive System Abnormalities; Doxylamine; Drug Combinations; Female; Head; Heart Defects, Congenital; Humans; Lung; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Pyridines; Pyridoxine; Urogenital Abnormalities; Vomiting	1989
Bendectin and interventricular septal defects. Teratology, 1985, Volume: 32, Issue:2 Topics: Centers for Disease Control and Prevention, U.S.; Dicyclomine; Doxylamine; Drug Combinations; Female; Heart Septal Defects, Ventricular; Humans; Infant, Newborn; Pregnancy; Pyridines; Pyridoxine; Teratogens; United States	1985
Agenesis of the corpus callosum and neural crest tumors. Pediatric hematology and oncology, 1986, Volume: 3, Issue:2 Topics: Abdominal Neoplasms; Abnormalities, Drug-Induced; Agenesis of Corpus Callosum; Child; Child, Preschool; Combined Modality Therapy; Dicyclomine; Doxylamine; Drug Combinations; Female; Fetal Alcohol Spectrum Disorders; Ganglioneuroma; Growth Disorders; Humans; Male; Mediastinal Neoplasms; Neural Crest; Neuroblastoma; Pregnancy; Prenatal Exposure Delayed Effects; Pyridoxine; Remission Induction	1986
A method for meta-analysis of epidemiological studies. Drug intelligence & clinical pharmacy, 1988, Volume: 22, Issue:10 Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Epidemiologic Methods; Humans; Meta-Analysis as Topic; Pyridoxine; Research Design; Statistics as Topic; Teratogens	1988
Discontinuation of Bendectin. American journal of public health, 1988, Volume: 78, Issue:3 Topics: Adult; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Nausea; Pregnancy; Pregnancy Complications; Pyloric Stenosis; Pyridines; Pyridoxine	1988
Factors associated with infantile hypertrophic pyloric stenosis. American journal of diseases of children (1960), 1988, Volume: 142, Issue:3 Topics: Birth Order; Breast Feeding; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Hypertrophy; Infant; Male; Maternal Age; Pregnancy; Pregnancy Complications; Pyloric Stenosis; Pyridoxine; Stress, Psychological	1988
Developmental toxicity evaluation of Bendectin in CD rats. Teratology, 1988, Volume: 37, Issue:6 Topics: Abnormalities, Drug-Induced; Animals; Antiemetics; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drinking Behavior; Drug Combinations; Feeding Behavior; Female; Litter Size; Male; Pregnancy; Pregnancy, Animal; Pyridines; Pyridoxine; Rats; Rats, Inbred Strains; Reference Values; Teratogens	1988
The value of case reports in human teratology. American journal of obstetrics and gynecology, 1986, Volume: 154, Issue:3 Topics: Abnormalities, Drug-Induced; Animals; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Erythromycin; Female; Humans; Infant, Newborn; Isotretinoin; Medical Records; Pregnancy; Publishing; Pyridoxine; Teratogens; Thalidomide; Tretinoin; Warfarin	1986
Debendox. The Medical journal of Australia, 1986, Mar-03, Volume: 144, Issue:5 Topics: Abnormalities, Drug-Induced; Antiemetics; Cleft Lip; Cleft Palate; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Pregnancy; Prenatal Exposure Delayed Effects; Pyridines; Pyridoxine	1986
The management of nausea and vomiting during pregnancy. The Medical journal of Australia, 1987, Sep-21, Volume: 147, Issue:6 Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Legislation, Drug; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Vomiting	1987
Limb-reduction deformities and Debendox. The Medical journal of Australia, 1987, Oct-05, Volume: 147, Issue:7 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Limb Deformities, Congenital; Pregnancy; Pyridines; Pyridoxine	1987
The weight of the evidence--or--more likely than not. Journal of craniofacial genetics and developmental biology, 1986, Volume: 6, Issue:3 Topics: Abnormalities, Drug-Induced; Dicyclomine; District of Columbia; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Jurisprudence; Legislation, Drug; Pregnancy; Pyridines; Pyridoxine; Teratogens	1986
Drugs and stillbirth. American journal of public health, 1986, Volume: 76, Issue:12 Topics: Abnormalities, Drug-Induced; Adult; Anti-Bacterial Agents; Contraceptives, Oral; Dicyclomine; Doxylamine; Drug Combinations; Female; Fetal Death; Health Surveys; Humans; Pregnancy; Pyridines; Pyridoxine; Spermatocidal Agents	1986
Comments on "Teratogen update:bendectin". Teratology, 1985, Volume: 31, Issue:3 Topics: Abnormalities, Drug-Induced; Bibliographies as Topic; Dicyclomine; Doxylamine; Drug Combinations; Humans; Jurisprudence; Pyridines; Pyridoxine	1985
The debendox saga. British medical journal (Clinical research ed.), 1985, Oct-05, Volume: 291, Issue:6500 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Pregnancy; Pyridines; Pyridoxine; Risk; United Kingdom	1985
Debendox. The Medical journal of Australia, 1986, Jan-06, Volume: 144, Issue:1 Topics: Abnormalities, Drug-Induced; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Pregnancy; Pyridines; Pyridoxine; Teratogens	1986
Jury clears Bendectin. Science (New York, N.Y.), 1985, Mar-29, Volume: 227, Issue:4694 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Jurisprudence; Pregnancy; Pyridines; Pyridoxine	1985
First-trimester drug use and congenital disorders. Obstetrics and gynecology, 1985, Volume: 65, Issue:4 Topics: Abnormalities, Drug-Induced; Brompheniramine; Congenital Abnormalities; Dicyclomine; Doxylamine; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Infant, Newborn; Phenylephrine; Phenylpropanolamine; Pregnancy; Pregnancy Trimester, First; Pseudoephedrine; Pyridoxine; Washington	1985
Congenital heart disease in relation to maternal use of Bendectin and other drugs in early pregnancy. The New England journal of medicine, 1985, Aug-08, Volume: 313, Issue:6 Topics: Acetaminophen; Adult; Anti-Bacterial Agents; Antiemetics; Aspirin; Dicyclomine; Doxylamine; Drug Combinations; Epidemiologic Methods; Female; Heart Defects, Congenital; Humans; Hyperemesis Gravidarum; Infant, Newborn; Male; Maternal-Fetal Exchange; Mental Recall; Pregnancy; Pregnancy Trimester, First; Pyridines; Pyridoxine; Surveys and Questionnaires	1985
Editorial comment on comments on "Teratogen update: Bendectin". Teratology, 1985, Volume: 31, Issue:3 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Humans; Methods; Pyridines; Pyridoxine	1985
Blame, compensation and birth defects. The Medical journal of Australia, 1985, Aug-19, Volume: 143, Issue:4 Topics: Abnormalities, Drug-Induced; Australia; Congenital Abnormalities; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Jurisprudence; Pregnancy; Pyridoxine; United States	1985
Debendox revisited. British journal of obstetrics and gynaecology, 1985, Volume: 92, Issue:8 Topics: Abnormalities, Drug-Induced; Antiemetics; Cleft Lip; Cleft Palate; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Nausea; Pregnancy; Pregnancy Complications; Pyridines; Pyridoxine; Risk; Smoking; Vomiting	1985
Debendox and birth defects. The Medical journal of Australia, 1985, Oct-14, Volume: 143, Issue:8 Topics: Congenital Abnormalities; Dicyclomine; Doxylamine; Drug Combinations; Humans; Infant, Newborn; Pyridines; Pyridoxine; Teratogens	1985
Evaluation of bendectin embryotoxicity in nonhuman primates: I. Ventricular septal defects in prenatal macaques and baboon. Teratology, 1985, Volume: 32, Issue:2 Topics: Animals; Dicyclomine; Dose-Response Relationship, Drug; Doxylamine; Drug Combinations; Female; Fetus; Heart Defects, Congenital; Heart Septal Defects, Ventricular; Humans; Macaca fascicularis; Macaca mulatta; Papio; Pregnancy; Pyridines; Pyridoxine; Species Specificity; Teratogens	1985
Evaluation of bendectin embryotoxicity in nonhuman primates: II. Double-blind study in term cynomolgus monkeys. Teratology, 1985, Volume: 32, Issue:2 Topics: Animals; Brain; Dicyclomine; Dose-Response Relationship, Drug; Double-Blind Method; Doxylamine; Drug Combinations; Drug Evaluation, Preclinical; Female; Fetus; Humans; Macaca fascicularis; Pregnancy; Pyridines; Pyridoxine; Teratogens	1985
Prune belly syndrome and heart defect in one of monozygotic twins, following exposure to Tigan and Bendectin. Acta geneticae medicae et gemellologiae, 1985, Volume: 34, Issue:1-2 Topics: Benzamides; Dicyclomine; Doxylamine; Drug Combinations; Heart Defects, Congenital; Humans; Prune Belly Syndrome; Pyridines; Pyridoxine; Twins; Twins, Monozygotic	1985
Inter-Regional Epidemiological Study of Childhood Cancer (IRESCC): childhood cancer and the consumption of debendox and related drugs in pregnancy. British journal of cancer, 1985, Volume: 52, Issue:6 Topics: Adolescent; Antiemetics; Child; Cyclohexanecarboxylic Acids; Dicyclomine; Dose-Response Relationship, Drug; Doxylamine; Drug Combinations; Female; Humans; Neoplasms; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Pyridines; Pyridoxine; Risk	1985
Circadian aspects of prostaglandin F2alpha-induced termination of pregnancy. The Journal of obstetrics and gynaecology of the British Commonwealth, 1974, Volume: 81, Issue:11 Topics: Abortion, Induced; Abortion, Therapeutic; Adult; Amniotic Fluid; Circadian Rhythm; Dextropropoxyphene; Dose-Response Relationship, Drug; Doxylamine; Female; Hospitalization; Humans; Injections; Length of Stay; Meperidine; Parity; Pregnancy; Pregnancy Trimester, First; Prostaglandins; Pyridoxine; Time Factors	1974
Safety of Debendox. Lancet (London, England), 1981, Mar-21, Volume: 1, Issue:8221 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Female; Fetal Death; Humans; Infant, Newborn; Pregnancy; Pyridines; Pyridoxine; Risk	1981
Debendox in pregnancy. Lancet (London, England), 1981, Jul-18, Volume: 2, Issue:8238 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Female; Fetus; Humans; Infant, Newborn; Pregnancy; Pyridines; Pyridoxine	1981
Bendectin (Debendox) and congenital diaphragmatic hernia. Lancet (London, England), 1983, Mar-12, Volume: 1, Issue:8324 Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Fetus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Pregnancy; Pyridines; Pyridoxine	1983
Bendectin (debendox) and congenital diaphragmatic hernia. Lancet (London, England), 1983, Apr-23, Volume: 1, Issue:8330 Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Pyridines; Pyridoxine	1983
Chromosomal studies on children with phocomelia, exposed to debendox during early pregnancy. Lancet (London, England), 1983, Aug-13, Volume: 2, Issue:8346 Topics: Chromosome Inversion; Dicyclomine; Doxylamine; Drug Combinations; Ectromelia; Female; Humans; Infant; Maternal-Fetal Exchange; Pregnancy; Pregnancy Trimester, First; Pyridines; Pyridoxine; Teratogens	1983
Teratogenicity of debendox and pyrimethamine. Lancet (London, England), 1983, Sep-10, Volume: 2, Issue:8350 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Pregnancy; Pyridines; Pyridoxine; Pyrimethamine	1983
Debendox is not thalidomide. Lancet (London, England), 1984, Jul-28, Volume: 2, Issue:8396 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Pregnancy; Pyridines; Pyridoxine	1984
Government resists "irresponsible" Debendox campaign. Lancet (London, England), 1984, Oct-27, Volume: 2, Issue:8409 Topics: Dicyclomine; Doxylamine; Drug Combinations; Humans; Jurisprudence; Pyridines; Pyridoxine; Teratogens; United Kingdom; United States	1984
Our bundle of responsibility. Presidential address. American journal of obstetrics and gynecology, 1984, Jun-01, Volume: 149, Issue:3 Topics: Abnormalities, Drug-Induced; Costs and Cost Analysis; Delivery of Health Care; Dicyclomine; Doxylamine; Drug Combinations; Female; Fertilization in Vitro; Forecasting; Health Policy; Humans; Jurisprudence; Medicaid; Medicare; Physician's Role; Pregnancy; Prenatal Diagnosis; Pyridoxine; Renal Dialysis; Role; United States; United States Food and Drug Administration	1984
Pyloric stenosis and maternal Bendectin exposure. American journal of epidemiology, 1984, Volume: 120, Issue:2 Topics: Adult; Dicyclomine; Doxylamine; Drug Combinations; Drug Prescriptions; Female; Follow-Up Studies; Humans; Hypertrophy; Infant; Infant, Newborn; Maternal Age; Maternal-Fetal Exchange; Nausea; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Prenatal Exposure Delayed Effects; Pyloric Stenosis; Pyridines; Pyridoxine; Risk	1984
Possible association of use of bendectin during early pregnancy and congenital lung hypoplasia. The New England journal of medicine, 1984, Sep-13, Volume: 311, Issue:11 Topics: Abnormalities, Drug-Induced; Adult; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant; Lung; Male; Pregnancy; Pregnancy Trimester, First; Pyridines; Pyridoxine	1984
Debendox and pregnancy. The Medical journal of Australia, 1984, Oct-13, Volume: 141, Issue:8 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Nausea; Pregnancy; Pregnancy Complications; Pyridines; Pyridoxine	1984
Debendox: a statement from the New Zealand Adverse Drug Reactions Committee. The New Zealand medical journal, 1984, Mar-28, Volume: 97, Issue:752 Topics: Antiemetics; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; New Zealand; Pregnancy; Pyridines; Pyridoxine	1984
No more bendectin. American family physician, 1983, Volume: 28, Issue:3 Topics: Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Combinations; Drug Industry; Female; Humans; Jurisprudence; Pregnancy; Pyridines; Pyridoxine	1983
Bendectin and pyloric stenosis. FDA drug bulletin, 1983, Volume: 13, Issue:2 Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Pregnancy; Pyloric Stenosis; Pyridines; Pyridoxine	1983
Bendectin: the wrong way to regulate drug availability. Canadian Medical Association journal, 1983, Nov-15, Volume: 129, Issue:10 Topics: Abnormalities, Drug-Induced; Canada; Dicyclomine; Doxylamine; Drug Combinations; Drug Industry; Female; Humans; Infant, Newborn; Legislation, Drug; Male; Pregnancy; Public Opinion; Pyridines; Pyridoxine; United States	1983
Nausea and vomiting of pregnancy. American family physician, 1983, Volume: 28, Issue:4 Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine	1983
Bendectin: a case of mourning sickness. Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:11 Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Nausea; Pregnancy; Pregnancy Complications; Pyridines; Pyridoxine; Teratogens	1983
Two legal issues: expert witnesses and Bendectin case. Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:11 Topics: Dicyclomine; Doxylamine; Drug Combinations; Expert Testimony; Female; Humans; Jurisprudence; Pregnancy; Pyridines; Pyridoxine; United States	1983
Birth defects in relation to Bendectin use in pregnancy. II. Pyloric stenosis. American journal of obstetrics and gynecology, 1983, Dec-01, Volume: 147, Issue:7 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Hyperemesis Gravidarum; Infant; Male; Maternal-Fetal Exchange; Pregnancy; Prenatal Care; Pyloric Stenosis; Pyridines; Pyridoxine; Risk; Sex Factors; Surveys and Questionnaires	1983
Bendectin and pyloric stenosis in infants. American journal of obstetrics and gynecology, 1983, Dec-15, Volume: 147, Issue:8 Topics: Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Pregnancy Trimester, First; Pyloric Stenosis; Pyridines; Pyridoxine	1983
Additional follow-up of congenital limb disorders in relation to Bendectin use. JAMA, 1983, Jul-01, Volume: 250, Issue:1 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Follow-Up Studies; Humans; Infant, Newborn; Pregnancy; Pregnancy Trimester, First; Pyridines; Pyridoxine	1983
Debendox withdrawn. The Medical journal of Australia, 1984, Jan-21, Volume: 140, Issue:2 Topics: Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Combinations; Humans; Pyridines; Pyridoxine	1984
Debendox withdrawn. The Medical journal of Australia, 1984, Mar-31, Volume: 140, Issue:7 Topics: Animals; Dicyclomine; Doxylamine; Drug Combinations; Pyridines; Pyridoxine; Teratogens	1984
The innocent bystander. Doxylamine/dicyclomine/pyridoxine and congenital limb defects. The Medical journal of Australia, 1984, Apr-28, Volume: 140, Issue:9 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Dose-Response Relationship, Drug; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Limb Deformities, Congenital; Nausea; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Pyridines; Pyridoxine; Retrospective Studies; Risk	1984
Good-bye, Bendectin, old friend. Postgraduate medicine, 1984, May-15, Volume: 75, Issue:7 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Drug Industry; Female; Humans; Infant, Newborn; Jurisprudence; Nausea; Pregnancy; Pregnancy Complications; Pyridines; Pyridoxine	1984
Debendox withdrawn. The Medical journal of Australia, 1984, Jun-23, Volume: 140, Issue:13 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Pregnancy; Pyridines; Pyridoxine	1984
Product liability all dressed up American style. British medical journal (Clinical research ed.), 1981, May-09, Volume: 282, Issue:6275 Topics: Antiemetics; Dicyclomine; Diethylstilbestrol; Doxylamine; Drug Combinations; Drug Industry; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Informed Consent; Legislation, Drug; Male; Pregnancy; Pyridoxine; United States	1981
Debendox and congenital malformations in Northern Ireland. British medical journal (Clinical research ed.), 1981, Jun-13, Volume: 282, Issue:6280 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Humans; Northern Ireland; Pyridines; Pyridoxine	1981
Debendox in early pregnancy and fetal malformation. British medical journal (Clinical research ed.), 1981, Jul-11, Volume: 283, Issue:6284 Topics: Abnormalities, Drug-Induced; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Combinations; England; Female; Humans; Infant; Infant, Newborn; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Pyridines; Pyridoxine; Scotland	1981
Prospective study of suspected associations between certain drugs administered during early pregnancy and congenital malformations. Teratology, 1983, Volume: 27, Issue:1 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Estradiol; Female; Germany, West; Humans; Pregnancy; Progesterone; Prospective Studies; Pyridoxine; Time Factors	1983
Congenital malformations. The New England journal of medicine, 1983, Aug-04, Volume: 309, Issue:5 Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Lithium; Pregnancy; Prenatal Diagnosis; Pyridoxine	1983
The Bendectin Saga: another American tragedy (Brent, '80). Teratology, 1983, Volume: 27, Issue:2 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Jurisprudence; Pregnancy; Pyridines; Pyridoxine; Teratogens; United States	1983
Debendox in the dock. Nursing mirror, 1980, Feb-21, Volume: 150, Issue:8 Topics: Abnormalities, Drug-Induced; Antiemetics; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Combinations; Drug Industry; Female; Florida; Government Agencies; Humans; Infant, Newborn; Jurisprudence; Pregnancy; Pyridines; Pyridoxine	1980
Bendectin use during pregnancy. The American journal of nursing, 1982, Volume: 82, Issue:11 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Pregnancy; Pyridines; Pyridoxine	1982
Bendectin and fetal development. A study of Boston City Hospital. American journal of obstetrics and gynecology, 1982, Jan-15, Volume: 142, Issue:2 Topics: Abnormalities, Drug-Induced; Antiemetics; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Interviews as Topic; Pregnancy; Prenatal Care; Prospective Studies; Pyridines; Pyridoxine; Risk; Teratogens	1982
The performance of three approximate confidence limit methods for the odds ratio. American journal of epidemiology, 1982, Volume: 115, Issue:3 Topics: Abnormalities, Drug-Induced; Breast Neoplasms; Dicyclomine; Doxylamine; Drug Combinations; Epidemiologic Methods; Estrogens; Female; Humans; Mouth Neoplasms; Pyridoxine; Risk; Smoking; Statistics as Topic	1982
Bendectin PPI available. FDA drug bulletin, 1982, Volume: 12, Issue:1 Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Drug Labeling; Female; Humans; Patient Education as Topic; Pregnancy; Pyridines; Pyridoxine	1982
Debendox does not cause the Poland anomaly. Archives of disease in childhood, 1982, Volume: 57, Issue:6 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Hand Deformities, Congenital; Humans; Infant, Newborn; Nausea; Pectoralis Muscles; Pregnancy; Pregnancy Complications; Pyridines; Pyridoxine; Retrospective Studies; Vomiting	1982
Multiple congenital abnormalities in a newborn boy associated with maternal use of fluphenazine enanthate and other drugs during pregnancy. Acta paediatrica Scandinavica, 1982, Volume: 71, Issue:2 Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Dicyclomine; Doxylamine; Female; Fluphenazine; Humans; Hypertelorism; Infant, Newborn; Male; Perineum; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pyridoxine; Schizophrenia, Disorganized	1982
Bendectin (Debendox) as a risk factor for pyloric stenosis. American journal of obstetrics and gynecology, 1982, Dec-15, Volume: 144, Issue:8 Topics: Abnormalities, Drug-Induced; Adult; Dicyclomine; Doxylamine; Drug Combinations; Female; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Pregnancy Trimester, First; Pyloric Stenosis; Pyridines; Pyridoxine; Risk; Smoking	1982
The law and Bendectin. American family physician, 1981, Volume: 23, Issue:4 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Jurisprudence; Pregnancy; Pyridines; Pyridoxine; United States; United States Food and Drug Administration	1981
Indications for bendectin narrowed. FDA drug bulletin, 1981, Volume: 11, Issue:1 Topics: Antiemetics; Carcinogens; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Pregnancy; Pregnancy Complications; Pyridines; Pyridoxine	1981
Is Bendectin a teratogen? JAMA, 1981, Jun-12, Volume: 245, Issue:22 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Drug Evaluation; Encephalocele; Esophageal Atresia; Female; Fetus; Humans; Infant, Newborn; Limb Deformities, Congenital; Maternal-Fetal Exchange; Nausea; Pregnancy; Pyridines; Pyridoxine; Teratogens	1981
Birth defects related to bendectin use in pregnancy. I. Oral clefts and cardiac defects. JAMA, 1981, Jun-12, Volume: 245, Issue:22 Topics: Antiemetics; Cleft Lip; Cleft Palate; Dicyclomine; Doxylamine; Drug Combinations; Drug Evaluation; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Pregnancy Trimester, First; Pyridines; Pyridoxine; Vomiting	1981
Congenital anomalies in relation to the use of doxylamine/dicyclomine and other antenatal factors: an ongoing prospective study. The Medical journal of Australia, 1981, Apr-18, Volume: 1, Issue:8 Topics: Abnormalities, Drug-Induced; Adult; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Combinations; Epidemiologic Methods; Female; Humans; Infant, Newborn; Male; Maternal Age; Maternal-Fetal Exchange; Parity; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Pyridines; Pyridoxine; Urogenital Abnormalities	1981
Debendox and limb reduction deformities. The Medical journal of Australia, 1981, Apr-18, Volume: 1, Issue:8 Topics: Abnormalities, Drug-Induced; Australia; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Limb Deformities, Congenital; Maternal-Fetal Exchange; Pregnancy; Pregnancy Trimester, First; Pyridines; Pyridoxine	1981
A dearth of new drugs. Nature, 1980, Feb-14, Volume: 283, Issue:5748 Topics: Abnormalities, Drug-Induced; Antiemetics; Doxylamine; Drug Combinations; Drug Evaluation; Drug Evaluation, Preclinical; Female; Humans; Jurisprudence; Legislation, Drug; Male; Pregnancy; Pyridines; Pyridoxine; United Kingdom; United States	1980
Debendox in pregnancy. The Medical journal of Australia, 1980, Mar-08, Volume: 1, Issue:5 Topics: Abnormalities, Drug-Induced; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Combinations; Female; Fetus; Humans; Pregnancy; Pyridines; Pyridoxine	1980
How safe is Bendectin? Science (New York, N.Y.), 1980, Oct-31, Volume: 210, Issue:4469 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Drug Evaluation; Female; Humans; Jurisprudence; Pregnancy; Pyridines; Pyridoxine; United States; United States Food and Drug Administration	1980
Debendox and congenital malformations in Northern Ireland. British medical journal, 1980, Nov-22, Volume: 281, Issue:6252 Topics: Abnormalities, Drug-Induced; Antiemetics; Cyclohexanecarboxylic Acids; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Northern Ireland; Pregnancy; Pregnancy Complications; Pyridines; Pyridoxine; Vomiting	1980
The Bendectin debate. Canadian Medical Association journal, 1980, Nov-08, Volume: 123, Issue:9 Topics: Abnormalities, Drug-Induced; Animals; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Jurisprudence; Nausea; Pregnancy; Pyridines; Pyridoxine; Rabbits; United States	1980
Public health issues: bendectin, love canal. Science (New York, N.Y.), 1981, Jan-02, Volume: 211, Issue:4477 Topics: Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; New York; Pregnancy; Pyridines; Pyridoxine; Teratogens; United States; United States Food and Drug Administration; Water Pollutants; Water Pollutants, Chemical	1981
Bendectin and fetal malformations. Canadian Medical Association journal, 1981, Feb-01, Volume: 124, Issue:3 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Pyridines; Pyridoxine; Teratogens	1981
Congenital symmetrical weakness of the upper limbs resembling brachial plexus palsy: a possible sequel of drug toxicity in first trimester of pregnancy? Neuromuscular disorders : NMD, 1995, Volume: 5, Issue:1 Topics: Age of Onset; Antiemetics; Arm; Dermatoglyphics; Diagnosis, Differential; Dicyclomine; Doxylamine; Drug Combinations; Female; Functional Laterality; Humans; Infant; Nausea; Nitrofurantoin; Paralysis; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Pyridoxine; Thoracic Outlet Syndrome; Urinary Tract Infections	1995
Bendectin case dismissed. Science (New York, N.Y.), 1995, Jan-13, Volume: 267, Issue:5195 Topics: Abnormalities, Drug-Induced; Antiemetics; Child; Dicyclomine; Doxylamine; Drug Combinations; Drug Industry; Expert Testimony; Humans; Pyridoxine	1995
Evaluating the admissibility of expert testimony. Hospital & community psychiatry, 1994, Volume: 45, Issue:1 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Expert Testimony; Humans; Insanity Defense; Pyridoxine; United States	1994
Science, law, and the search for truth in the courtroom: lessons from Daubert v. Merrell Dow. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics, 1994,Spring, Volume: 22, Issue:1 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Expert Testimony; Female; Humans; Infant, Newborn; Pregnancy; Pyridoxine; Research; United States	1994
Admissibility of scientific testimony into evidence. American journal of hospital pharmacy, 1994, Mar-01, Volume: 51, Issue:5 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Drug Industry; Expert Testimony; Female; Humans; Pregnancy; Pyridoxine; Teratogens; United States	1994
Study of prescription drugs in the first trimester and congenital malformations. The Australian & New Zealand journal of obstetrics & gynaecology, 1993, Volume: 33, Issue:2 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Pregnancy; Pyridoxine	1993
Environmental hazards: real or exaggerated? Science (New York, N.Y.), 1993, Oct-29, Volume: 262, Issue:5134 Topics: Dicyclomine; Doxylamine; Drug Combinations; Female; Hazardous Substances; Humans; Pregnancy; Pyridoxine	1993
Supreme Court to judges: start thinking like scientists. Science (New York, N.Y.), 1993, Jul-02, Volume: 261, Issue:5117 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Drug Industry; Expert Testimony; Humans; Pyridoxine; United States	1993
Court ruling on 'junk science' gives judges more say about what expert witness testimony to allow. JAMA, 1993, Jul-28, Volume: 270, Issue:4 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Drug Industry; Expert Testimony; Humans; Jurisprudence; Pyridoxine; United States	1993
Supreme Court to weigh science. Science (New York, N.Y.), 1993, Jan-29, Volume: 259, Issue:5095 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Expert Testimony; Female; Government Agencies; Humans; Pregnancy; Pyridoxine; Science; Societies, Scientific; United States	1993
Criteria for science in the courts. Nature, 1993, Apr-08, Volume: 362, Issue:6420 Topics: Dicyclomine; Doxylamine; Drug Combinations; Expert Testimony; Humans; Jurisprudence; Limb Deformities, Congenital; Pyridoxine; Science; United States	1993
Bringing scholarship to the courtroom: the Daubert decision and its impact on the Teratology Society. Teratology, 1995, Volume: 52, Issue:5 Topics: Dicyclomine; Doxylamine; Drug Combinations; Ethics, Professional; Expert Testimony; Female; Humans; Malpractice; Pregnancy; Product Surveillance, Postmarketing; Pyridoxine; Social Responsibility; Societies, Medical; Societies, Scientific; Teratogens; Teratology; United States	1995
Alert over sound-alike drugs. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1997, Jul-01, Volume: 157, Issue:1 Topics: Antiemetics; Calcium Channel Blockers; Canada; Dicyclomine; Doxylamine; Drug Combinations; Humans; Medication Errors; Morpholines; Pyridoxine; Terminology as Topic	1997
Drug therapies for hyperemesis gravidarum. Canadian family physician Medecin de famille canadien, 1997, Volume: 43 Topics: Administration, Oral; Antiemetics; Doxylamine; Female; Humans; Hyperemesis Gravidarum; Infusions, Intravenous; Pregnancy; Pyridoxine	1997
Alarums false, alarums real: challenges and threats to the future of epidemiology. Annals of epidemiology, 1998, Volume: 8, Issue:2 Topics: Antiemetics; Breast Implants; Confidentiality; Dicyclomine; Doxylamine; Drug Combinations; Epidemiology; Humans; Journalism, Medical; Managed Care Programs; Pyridoxine; Telephone; United States	1998
Pregnancy outcome of women exposed to pinaverium due to a dispensing error. The Annals of pharmacotherapy, 1999, Volume: 33, Issue:1 Topics: Antiemetics; Calcium Channel Blockers; Canada; Dicyclomine; Doxylamine; Drug Combinations; Female; Follow-Up Studies; Humans; Medication Errors; Morpholines; Nausea; Pregnancy; Pyridoxine	1999
From science to evidence: the testimony on causation in the Bendectin cases. Stanford law review, 1993, Volume: 46, Issue:1 Topics: Abnormalities, Drug-Induced; Data Collection; Decision Making; Doxylamine; Drug Combinations; Expert Testimony; Female; Humans; Liability, Legal; Nausea; Pregnancy; Pyridoxine; Science; United States	1993
Is "junk science" finally on the way out? Medical economics, 1996, Apr-29, Volume: 73, Issue:8 Topics: Antiemetics; Breast Implants; Dicyclomine; Doxylamine; Drug Combinations; Expert Testimony; Female; Humans; Malpractice; Mass Media; Peer Review, Health Care; Pyridoxine; Silicon; United States	1996
Daubert v. Merrell Dow: missed opportunity. Food and drug law journal, 1995, Volume: 50, Issue:1 Topics: Abnormalities, Drug-Induced; Antiemetics; Doxylamine; Drug Combinations; Drug Industry; Expert Testimony; Guidelines as Topic; Humans; Legislation, Medical; Liability, Legal; Pyridoxine; United States	1995
Simultaneous determination of pyridoxine hydrochloride and doxylamine succinate from tablets by ion pair reversed-phase high-performance liquid chromatography (RP-HPLC). Drug development and industrial pharmacy, 1999, Volume: 25, Issue:8 Topics: Chromatography, High Pressure Liquid; Doxylamine; Drug Stability; Histamine H1 Antagonists; Linear Models; Pyridoxine; Reproducibility of Results; Tablets	1999
Managing women with nausea and vomiting of pregnancy. Canadian consensus. Canadian family physician Medecin de famille canadien, 2000, Volume: 46 Topics: Adult; Anti-Inflammatory Agents; Antiemetics; Asthma; Diagnosis, Differential; Doxylamine; Drug Therapy, Combination; Female; Humans; Nausea; Prednisone; Pregnancy; Pregnancy Complications; Pyridoxine; Vomiting	2000
Attitudes, management and consequences of nausea and vomiting of pregnancy in the United States and Canada. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2000, Volume: 70, Issue:3 Topics: Adult; Antiemetics; Attitude; Attitude of Health Personnel; Canada; Cost of Illness; Dicyclomine; Diet; Doxylamine; Drug Combinations; Female; Humans; Life Style; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; United States; Vomiting	2000
The safety of higher than standard dose of doxylamine-pyridoxine (Diclectin) for nausea and vomiting of pregnancy. Journal of clinical pharmacology, 2001, Volume: 41, Issue:8 Topics: Antiemetics; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Nausea; Pregnancy; Pregnancy Complications; Prospective Studies; Pyridoxine; Vomiting	2001
Prenatal prescription of macrolide antibiotics and infantile hypertrophic pyloric stenosis. Obstetrics and gynecology, 2003, Volume: 101, Issue:4 Topics: Anti-Bacterial Agents; Confounding Factors, Epidemiologic; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Infant, Newborn; Macrolides; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Pyloric Stenosis; Pyridoxine	2003
Bendectin and birth defects: hopefully, the final chapter. Birth defects research. Part A, Clinical and molecular teratology, 2003, Volume: 67, Issue:2 Topics: Abnormalities, Drug-Induced; Adult; Adverse Drug Reaction Reporting Systems; Animals; Antiemetics; Case-Control Studies; Dicyclomine; Doxylamine; Drug Approval; Drug Combinations; Female; Fetus; Humans; Infant, Newborn; Liability, Legal; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Safety; United States; United States Food and Drug Administration; Vomiting	2003
Bendectin and birth defects. II: Ecological analyses. Birth defects research. Part A, Clinical and molecular teratology, 2003, Volume: 67, Issue:2 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Adverse Drug Reaction Reporting Systems; Animals; Antiemetics; Dicyclomine; Doxylamine; Drug Approval; Drug Combinations; Drug Utilization; Female; Fetus; Hospitalization; Humans; Incidence; Infant, Newborn; Liability, Legal; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Safety; United States; United States Food and Drug Administration; Vomiting	2003
Bendectin in the treatment of nausea of pregnancy. The Ohio State medical journal, 1957, Volume: 53, Issue:6 Topics: Dicyclomine; Doxylamine; Drug Combinations; Histamine H1 Antagonists; Muscle Relaxants, Central; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Vitamin B 6	1957
Nausea and vomiting of pregnancy: treatment with bendectin. International record of medicine and general practice clinics, 1958, Volume: 171, Issue:9 Topics: Dicyclomine; Doxylamine; Drug Combinations; Histamine H1 Antagonists; Muscle Relaxants, Central; Nausea; Pregnancy; Pyridoxine; Vitamin B 6; Vomiting	1958
Bendectin in the treatment of nausea and vomiting in pregnancy. Obstetrics and gynecology, 1959, Volume: 14 Topics: Dicyclomine; Doxylamine; Drug Combinations; Histamine H1 Antagonists; Muscle Relaxants, Central; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Vitamin B 6; Vomiting	1959
Diclectin therapy for nausea and vomiting of pregnancy: effects of optimal dosing. Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2003, Volume: 25, Issue:10 Topics: Adult; Antiemetics; Dose-Response Relationship, Drug; Doxylamine; Drug Combinations; Female; Humans; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Severity of Illness Index; Vomiting	2003
Science v. law. A decade-old rule on scientific evidence comes under fire. Scientific American, 2003, Volume: 289, Issue:6 Topics: Abnormalities, Drug-Induced; Dicyclomine; Doxylamine; Drug Combinations; Drug Industry; Expert Testimony; Humans; Judicial Role; Jurisprudence; Liability, Legal; Pyridoxine; Science	2003
The negative impact of litigation on women's health care. Gender medicine, 2005, Volume: 2, Issue:4 Topics: Antiemetics; Breast Implants; Defensive Medicine; Dicyclomine; Doxylamine; Drug Combinations; Female; Hormone Replacement Therapy; Humans; Liability, Legal; Mass Media; Pyridoxine; Research Support as Topic; Women's Health	2005
American Gastroenterological Association institute medical position statement on the use of gastrointestinal medication in pregnancy. Gastroenterology, 2007, Volume: 132, Issue:2 Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Gastrointestinal Agents; Gastrointestinal Diseases; Humans; Morning Sickness; Nausea; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications; Pyridoxine; Societies, Medical; United States; Vomiting	2007
Preventing recurrence of severe morning sickness. Canadian family physician Medecin de famille canadien, 2006, Volume: 52, Issue:12 Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Morning Sickness; Ondansetron; Pregnancy; Pyridoxine; Secondary Prevention	2006
Long-term neurodevelopment of children exposed to maternal nausea and vomiting of pregnancy and diclectin. The Journal of pediatrics, 2009, Volume: 155, Issue:1 Topics: Adult; Antiemetics; Child; Child Development; Child, Preschool; Cohort Studies; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Intelligence; Intelligence Tests; Linear Models; Maternal-Fetal Exchange; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Severity of Illness Index; Sleep; Vomiting	2009
Systemic bioavailability and pharmacokinetics of the doxylamine-pyridoxine delayed-release combination (Diclectin). Therapeutic drug monitoring, 2011, Volume: 33, Issue:1 Topics: Adult; Antiemetics; Biological Availability; Canada; Delayed-Action Preparations; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Nausea; Pregnancy; Pregnancy Complications; Pyridoxal Phosphate; Pyridoxine; Tablets; Vomiting; Young Adult	2011
Epidemiological evidence in forensic pharmacovigilance. The International journal of risk & safety in medicine, 2012, Volume: 24, Issue:1 Topics: Abnormalities, Drug-Induced; Antiemetics; Breast Implantation; Causality; Connective Tissue Diseases; Dicyclomine; Doxylamine; Drug Combinations; Female; Forensic Sciences; Humans; Pharmacoepidemiology; Pharmacology; Pharmacovigilance; Pregnancy; Pyridoxine	2012
Evaluation of the efficacy and safety of bi-daily combination therapy with pyridoxine and doxylamine for nausea and vomiting of pregnancy. The Israel Medical Association journal : IMAJ, 2013, Volume: 15, Issue:1 Topics: Administration, Oral; Adult; Antiemetics; Case-Control Studies; Dicyclomine; Dose-Response Relationship, Drug; Doxylamine; Drug Administration Schedule; Drug Combinations; Female; Humans; Nausea; Pregnancy; Pregnancy Complications; Prospective Studies; Pyridoxine; Surveys and Questionnaires; Treatment Outcome; Vitamin B Complex; Vomiting	2013
The return to the USA of doxylamine-pyridoxine delayed release combination (Diclegis®) for morning sickness--a new morning for American women. Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique, 2013, Volume: 20, Issue:2 Topics: Antiemetics; Delayed-Action Preparations; Dicyclomine; Doxylamine; Drug Approval; Drug Combinations; Drug Labeling; Female; Humans; Morning Sickness; Pregnancy; Pyridoxine; United States; United States Food and Drug Administration	2013
Diclegis for nausea and vomiting of pregnancy. The Medical letter on drugs and therapeutics, 2013, Aug-05, Volume: 55, Issue:1422 Topics: Antiemetics; Delayed-Action Preparations; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Vomiting	2013
Characteristics of women with nausea and vomiting of pregnancy who chose to continue compassionate use of placebo after a randomised trial. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2013, Volume: 33, Issue:6 Topics: Adult; Dicyclomine; Double-Blind Method; Doxylamine; Drug Combinations; Female; Histamine H1 Antagonists; Humans; Logistic Models; Morning Sickness; Placebo Effect; Pregnancy; Pyridoxine; Randomized Controlled Trials as Topic; Young Adult	2013
Concern for truth: driving defensively when confronting a zombie epidemic. Journal of psychosocial nursing and mental health services, 2013, Volume: 51, Issue:11 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; History, 20th Century; Humans; Internet; Pregnancy; Pyridoxine; Thalidomide; United States	2013
Diclegis: return of a medication. South Dakota medicine : the journal of the South Dakota State Medical Association, 2013, Volume: 66, Issue:12 Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Approval; Drug Combinations; Female; Humans; Morning Sickness; Pregnancy; Pyridoxine; United States	2013
FDA approval of doxylamine-pyridoxine therapy for use in pregnancy. The New England journal of medicine, 2014, Mar-20, Volume: 370, Issue:12 Topics: Antiemetics; Congenital Abnormalities; Dicyclomine; Doxylamine; Drug Approval; Drug Combinations; Female; History, 20th Century; Humans; Morning Sickness; Pregnancy; Pyridoxine; United States; United States Food and Drug Administration	2014
Should doxylamine-pyridoxine be used for nausea and vomiting of pregnancy? Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2014, Volume: 36, Issue:4 Topics: Abnormalities, Drug-Induced; Antiemetics; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Morning Sickness; Neoplasms; Practice Guidelines as Topic; Pregnancy; Pyloric Stenosis; Pyridoxine; Randomized Controlled Trials as Topic	2014
Treating morning sickness in the United States--changes in prescribing are needed. American journal of obstetrics and gynecology, 2014, Volume: 211, Issue:6 Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Approval; Drug Combinations; Female; Heart Defects, Congenital; Humans; Morning Sickness; Ondansetron; Practice Patterns, Physicians'; Pregnancy; Pyridoxine; Serotonin Syndrome; Torsades de Pointes; United States; United States Food and Drug Administration	2014
Ondansetron compared with doxylamine and pyridoxine for treatment of nausea in pregnancy: a randomized controlled trial. Obstetrics and gynecology, 2015, Volume: 125, Issue:2 Topics: Doxylamine; Female; Humans; Morning Sickness; Ondansetron; Pregnancy; Pyridoxine	2015
Odansetron compared with doxylamine and pyridoxine for treatment of nausea in pregnancy: a randomized controlled trial. Obstetrics and gynecology, 2015, Volume: 125, Issue:2 Topics: Doxylamine; Female; Humans; Morning Sickness; Ondansetron; Pregnancy; Pyridoxine	2015
In reply. Obstetrics and gynecology, 2015, Volume: 125, Issue:2 Topics: Doxylamine; Female; Humans; Morning Sickness; Ondansetron; Pregnancy; Pyridoxine	2015
Flawed invisible trial underpins US morning sickness drug, researchers say. BMJ (Clinical research ed.), 2017, Jan-09, Volume: 356 Topics: Antiemetics; Clinical Trials as Topic; Dicyclomine; Doxylamine; Drug Approval; Drug Combinations; Female; Humans; Morning Sickness; Pregnancy; Pyridoxine	2017
Motherisk and Canadian Family Physician. Canadian family physician Medecin de famille canadien, 2017, Volume: 63, Issue:1 Topics: Canada; Doxylamine; Female; Guideline Adherence; Humans; Hyperemesis Gravidarum; Physicians, Family; Practice Guidelines as Topic; Pregnancy; Pyridoxine; Societies, Medical	2017
Advanced spectrophotometric chemometric methods for resolving the binary mixture of doxylamine succinate and pyridoxine hydrochloride. Acta pharmaceutica (Zagreb, Croatia), 2018, Mar-01, Volume: 68, Issue:1 Topics: Calibration; Doxylamine; Drug Compounding; Least-Squares Analysis; Multivariate Analysis; Pyridoxine; Spectrophotometry	2018
Chemical cross-linking: A feasible approach to prolong doxylamine/pyridoxine release from spray-dried chitosan microspheres. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, Oct-15, Volume: 123 Topics: Adhesiveness; Administration, Intranasal; Antiemetics; Chemistry, Pharmaceutical; Chitosan; Cross-Linking Reagents; Delayed-Action Preparations; Dicyclomine; Doxylamine; Drug Carriers; Drug Combinations; Drug Compounding; Drug Liberation; Feasibility Studies; Gastric Mucins; Glutaral; Kinetics; Microspheres; Pyridoxine; Solubility	2018
Drug updates and approvals: 2018 in review. The Nurse practitioner, 2018, Volume: 43, Issue:12 Topics: Adenine; Alanine; Amides; Aminophenols; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzodioxoles; Clonidine; Doxylamine; Drug Approval; Emtricitabine; Heterocyclic Compounds, 3-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Indoles; Piperazines; Pyridones; Pyridoxine; Quinolones; Tenofovir; United States; United States Food and Drug Administration	2018
New evidence for concern over the risk of birth defects from medications for nausea and vomitting of pregnancy. Journal of clinical epidemiology, 2019, Volume: 116 Topics: Abnormalities, Drug-Induced; Adult; Antiemetics; Cohort Studies; Dicyclomine; Doxylamine; Drug Combinations; Female; Humans; Male; Maternal Age; Metoclopramide; Nausea; Ondansetron; Pregnancy; Pregnancy Trimester, First; Prevalence; Pyridoxine; Quebec; Vomiting; Young Adult	2019
Protection Versus Progress: The Challenge of Research on Cannabis Use During Pregnancy. Pediatrics, 2020, Volume: 146, Issue:Suppl 1 Topics: Antiemetics; Dicyclomine; Doxylamine; Drug Approval; Drug Combinations; Ethics, Research; Female; Humans; Medical Marijuana; Morning Sickness; Ondansetron; Pediatrics; Pregnancy; Pregnant Women; Pyridoxine; Research Subjects; Teratogens; Thalidomide	2020
Harnessing of Doxylamine Succinate/Pyridoxine Hydrochloride-Dual Laden Bilosomes as a Novel Combinatorial Nanoparadigm for Intranasal Delivery: In Vitro Optimization and In Vivo Pharmacokinetic Appraisal. Journal of pharmaceutical sciences, 2022, Volume: 111, Issue:3 Topics: Administration, Intranasal; Animals; Biological Availability; Doxylamine; Drug Delivery Systems; Gels; Particle Size; Pyridoxine; Rats	2022
Comparative dissolution profiles of two anti-emetic delayed release dosage forms of doxylamine and pyridoxine: Xonvea® tablets vs. Cariban® capsules. European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:12 Topics: Antiemetics; Doxylamine; Female; Gastrointestinal Agents; Humans; Nausea; Pregnancy; Pyridoxine; Solubility; Tablets	2022
Comment on: Comparative dissolution profiles of two anti-emetic delayed-release dosage forms of doxylamine and pyridoxine: Xonvea® tablets vs. Cariban® capsules. European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:22 Topics: Antiemetics; Capsules; Doxylamine; Gastrointestinal Agents; Pyridoxine; Solubility; Tablets	2022
Reply Letter - to Urso et al "Comment on: Comparative dissolution profiles of two anti-emetic delayed release dosage forms of doxylamine and pyridoxine: Xonvea® tablets vs. Cariban® capsules". European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:23 Topics: Antiemetics; Capsules; Delayed-Action Preparations; Doxylamine; Gastrointestinal Agents; Pyridoxine; Solubility; Tablets; Ursodeoxycholic Acid	2022
Bioavailability of Cariban Drugs in R&D, 2023, Volume: 23, Issue:2 Topics: Adult; Antiemetics; Biological Availability; Capsules; Delayed-Action Preparations; Doxylamine; Drug Combinations; Female; Humans; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Vomiting	2023