doxylamine has been researched along with doxylamine succinate in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (35.71) | 18.7374 |
| 1990's | 8 (19.05) | 18.2507 |
| 2000's | 7 (16.67) | 29.6817 |
| 2010's | 10 (23.81) | 24.3611 |
| 2020's | 2 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Greenblatt, DJ; Luna, BG; Scavone, JM | 1 |
| Korte, A; Madle, S; Müller, L | 1 |
| Gosnell, AB; Holder, CL; Korfmacher, WA; Slikker, W; Thompson, HC | 1 |
| Holder, CL; Luck, W; Nau, H; Roberts, LG; Scott, WJ; Slikker, W | 1 |
| Gosnell, AB; Holder, CL; Korfmacher, WA; Lay, JO; Miller, DW; Siitonen, P | 1 |
| Bowman, MC; Holder, CL; Thompson, HC | 1 |
| Bookstaff, RC; Heise, MA; Horowitz, ZD; Murphy, VA; Parkinson, A; Powell, JH; Skare, JA; St Peter, JV; Thompson, GA | 1 |
| Caillaud, JM; Chevalier, J; Renault, JY | 1 |
| Miller, CH; Ognibere, AJ; Soto, LF | 1 |
| Borum, P; Eccles, R; Tetzloff, W; Van Cauwenberge, P | 1 |
| Bookstaff, RC; Minnema, D; Murphy, VA; Parkinson, A; Sanzgiri, U; Skare, JA | 1 |
| Ballús, J; Marruecos, L; Paytubí Garí, C | 1 |
| Gaylor, DW; Kodell, RL | 1 |
| Argekar, AP; Sawant, JG | 1 |
| Fasseas, P; Leybishkis, B; Ryan, KF | 1 |
| du Plessis, J; du Preez, JL; Goosen, C; Müller, DG; Pelser, A | 1 |
| Bashkirova, LM; Korzhenevskiĭ, LV; Rudenko, AE | 1 |
| CANY, J; HUIDOBRO, H | 1 |
| LIACOPOULOS, P; WOLFROMM, R | 1 |
| LAJOUANINE, P; MAURICE, A; ROURE, H | 1 |
| GESLIN, A; ROURE, H | 1 |
| Khetrapal, CL; Nagana Gowda, GA; Ramesha, AR; Somashekar, BS | 1 |
| Hasemann, P; Preu, L; ter Balk, M; Wätzig, H | 1 |
| Goodale, M; Grender, JM; Hull, JD; Jerdack, GR; Mizoguchi, H; Tyler, BA; Wilson, A | 1 |
| SHELDON, JM; WELLER, KE | 1 |
| THOMPSON, CR; WERNER, HW | 1 |
| KLAHM, GR; SNYDER, FH; WERNER, HW | 1 |
| BERNSTEIN, TB; FEINBERG, SM | 1 |
| BROWN, EA; MAHER, JP; WEISS, LR | 1 |
| Koren, G; Nulman, I | 1 |
| Caritis, S; Chiossi, G; Clark, S; Costantine, MM; Hankins, GD; Koren, G; Matok, I; Miodovnik, M; Umans, JG | 1 |
| Carrascosa, MF; Caviedes, JR; Cuadrado-Lavín, A; Lucena, MI | 1 |
| Encina, G; Guibord, P; Lahjou, M; Sans, A; Sicard, E; Tolrà, C; Videla, S; Xu, Z | 1 |
| Cabot, A; Cebrecos, J; Encabo, M; Encina, G; Guibord, P; Lahjou, M; Sans, A; Sicard, E; Videla, S; Wagner, F; Xu, Z | 1 |
| Balan, G; Gibb, R; Hull, D; Li, L; Seeck, M; Thompson, GA | 1 |
| Clark, SM; Dutta, E; Hankins, GD | 1 |
| Essam, HM; Yehia, AM | 1 |
| Al-Degs, Y; Alin, A; Gergov, G; Kassarova, M; Katsarov, P; Pilicheva, B; Simeonov, V | 1 |
| Byland, E; Canupp, K; Dunlap, J; Mospan, C; Mospan, G; Whitaker, WB; Xiong, L | 1 |
| Derinöz-Güleryüz, O | 1 |
| Aboud, HM; Ali, AA; Hegazy, AM; Sadek, AA; Salem, HF | 1 |
| Abd El-Hadi, HR; Eissa, MS; Eltanany, BM; Zaazaa, HE | 1 |
4 review(s) available for doxylamine and doxylamine succinate
| Article | Year |
|---|---|
Safety assessment of OTC drugs: doxylamine succinate.
Topics: Animals; Doxylamine; Histamine H1 Antagonists; Humans; Mice; Mutagens; Nonprescription Drugs; Rats | 1995 |
[Nontraumatic rhabdomyolysis due to oral poisoning by doxylamine succinate].
Topics: Acute Disease; Adult; Doxylamine; Histamine H1 Antagonists; Humans; Male; Poisoning; Rhabdomyolysis; Suicide, Attempted | 1997 |
Dose-response trend tests for tumorigenesis, adjusted for body weight.
Topics: Age Factors; Anisoles; Body Weight; Carcinogenicity Tests; Dose-Response Relationship, Drug; Doxylamine; Neoplasms; Nitrobenzoates; Statistics as Topic; Time Factors | 1999 |
The outpatient management and special considerations of nausea and vomiting in pregnancy.
Topics: Ambulatory Care; Antiemetics; Diet Therapy; Doxylamine; Female; Fluid Therapy; Gastroesophageal Reflux; Histamine H1 Antagonists; Humans; Hyperemesis Gravidarum; Metoclopramide; Morning Sickness; Ondansetron; Pregnancy; Promethazine; Pyridoxine; Severity of Illness Index; Vitamin B Complex | 2014 |
8 trial(s) available for doxylamine and doxylamine succinate
| Article | Year |
|---|---|
A clinical study to evaluate the efficacy of the antihistamine doxylamine succinate in the relief of runny nose and sneezing associated with upper respiratory tract infection.
Topics: Common Cold; Double-Blind Method; Doxylamine; Histamine H1 Antagonists; Humans; Respiratory Tract Infections; Sneezing | 1995 |
[A new approach to the treatment of sleep disorders in patients with cerebrovascular diseases].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Azabicyclo Compounds; Cerebrovascular Disorders; Doxylamine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Piperazines; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 2003 |
Efficacy of a single evening dose of syrup containing paracetamol, dextromethorphan hydrobromide, doxylamine succinate and ephedrine sulfate in subjects with multiple common cold symptoms.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Antitussive Agents; Bronchodilator Agents; Common Cold; Dextromethorphan; Double-Blind Method; Doxylamine; Drug Combinations; Ephedrine; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Prospective Studies; Sleep Wake Disorders | 2007 |
Pharmacokinetic comparison of a delayed-release combination of doxylamine succinate and pyridoxine hydrocholoride (Diclectin) and oral solutions of these drugs in healthy women of childbearing age.
Topics: Adult; Antiemetics; Area Under Curve; Biological Availability; Cross-Over Studies; Delayed-Action Preparations; Doxylamine; Drug Combinations; Female; Humans; Pregnancy; Pyridoxal; Pyridoxal Phosphate; Pyridoxine; Solutions; Tablets | 2009 |
Determinants of adherence to delayed-release doxylamine and pyridoxine in patients with nausea and vomiting of pregnancy.
Topics: Adult; Antiemetics; Cohort Studies; Delayed-Action Preparations; Dicyclomine; Double-Blind Method; Doxylamine; Drug Combinations; Female; Humans; Medication Adherence; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Vomiting | 2012 |
Food effects on the pharmacokinetics of doxylamine hydrogen succinate 25 mg film-coated tablets: a single-dose, randomized, two-period crossover study in healthy volunteers.
Topics: Administration, Oral; Adult; Area Under Curve; Biological Availability; Cross-Over Studies; Doxylamine; Fasting; Female; Food-Drug Interactions; Half-Life; Humans; Male; Middle Aged; Tablets; Tablets, Enteric-Coated; Young Adult | 2012 |
Pharmacokinetic dose proportionality between two strengths (12.5 mg and 25 mg) of doxylamine hydrogen succinate film-coated tablets in fasting state: a single-dose, randomized, two-period crossover study in healthy volunteers.
Topics: Adult; Biological Availability; Cross-Over Studies; Dose-Response Relationship, Drug; Doxylamine; Fasting; Female; Healthy Volunteers; Histamine H1 Antagonists; Humans; Male; Medication Adherence; Middle Aged; Tablets | 2013 |
Doxylamine pharmacokinetics following single dose oral administration in children ages 2-17 years.
Topics: Administration, Oral; Adolescent; Area Under Curve; Child; Child, Preschool; Dose-Response Relationship, Drug; Doxylamine; Female; Histamine H1 Antagonists; Humans; Male | 2013 |
30 other study(ies) available for doxylamine and doxylamine succinate
| Article | Year |
|---|---|
Doxylamine and diphenhydramine pharmacokinetics in women on low-dose estrogen oral contraceptives.
Topics: Adult; Diphenhydramine; Doxylamine; Ethinyl Estradiol; Female; Half-Life; Humans; Metabolic Clearance Rate; Pyridines | 1989 |
Mutagenicity testing of doxylamine succinate, an antinauseant drug.
Topics: Animals; Antiemetics; Bone Marrow; Chromosome Aberrations; Cricetinae; Cricetulus; Doxylamine; Embryo, Mammalian; Female; Fetal Blood; Humans; Lymphocytes; Male; Maternal-Fetal Exchange; Mice; Micronucleus Tests; Mutagens; Pregnancy; Pyridines; Sister Chromatid Exchange | 1989 |
Mass spectral characterization of doxylamine and its rhesus monkey urinary metabolites.
Topics: Animals; Chromatography, High Pressure Liquid; Doxylamine; Histamine H1 Antagonists; Macaca mulatta; Mass Spectrometry; Pyridines | 1985 |
Embryo-maternal distribution of basic compounds in the CD-1 mouse: doxylamine and nicotine.
Topics: Animals; Biological Transport; Doxylamine; Embryo, Mammalian; Female; Hydrogen-Ion Concentration; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Muscles; Nicotine; Pregnancy; Pyridines; Time Factors | 1989 |
Desorption chemical ionization and fast atom bombardment mass spectrometric studies of the glucuronide metabolites of doxylamine.
Topics: Animals; Chromatography, High Pressure Liquid; Doxylamine; Glucuronates; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Pyridines; Rats; Rats, Inbred F344 | 1986 |
Trace analysis of doxylamine succinate in animal feed, human, urine, and wastewater by GC using a rubidium-sensitized nitrogen detector.
Topics: Animal Feed; Animals; Chromatography, Gas; Chromatography, High Pressure Liquid; Doxylamine; Histamine H1 Antagonists; Humans; Pyridines; Waste Products; Water | 1982 |
Ultrastructural characterization of normal and abnormal chondrogenesis in micromass rat embryo limb bud cell cultures.
Topics: 6-Aminonicotinamide; Animals; Cartilage; Cells, Cultured; Doxylamine; Embryo, Mammalian; Embryonic and Fetal Development; Female; Forelimb; Histamine H1 Antagonists; Rats; Rats, Sprague-Dawley; Teratogens; Tretinoin | 1995 |
Severe rhabdomyolysis after doxylamine overdose.
Topics: Adult; Bicarbonates; Creatine Kinase; Doxylamine; Drug Overdose; Epilepsy, Tonic-Clonic; Histamine H1 Antagonists; Humans; Intubation, Intratracheal; Male; Rhabdomyolysis; Schizophrenia, Paranoid; Sodium; Sodium Bicarbonate; Suicide, Attempted | 1993 |
Effects of doxylamine succinate on thyroid hormone balance and enzyme induction in mice.
Topics: Animals; Cytochrome P-450 Enzyme System; Doxylamine; Enzyme Induction; Female; Histamine H1 Antagonists; Hydroxylation; Lauric Acids; Male; Mice; Microsomes, Liver; Phenobarbital; Testosterone; Thyroid Hormones | 1996 |
Simultaneous determination of pyridoxine hydrochloride and doxylamine succinate from tablets by ion pair reversed-phase high-performance liquid chromatography (RP-HPLC).
Topics: Chromatography, High Pressure Liquid; Doxylamine; Drug Stability; Histamine H1 Antagonists; Linear Models; Pyridoxine; Reproducibility of Results; Tablets | 1999 |
Doxylamine overdose as a potential cause of rhabdomyolysis.
Topics: Acute Kidney Injury; Adult; Doxylamine; Drug Overdose; Histamine H1 Antagonists; Humans; Male; Nonprescription Drugs; Rhabdomyolysis; Self Medication | 2001 |
Comparative pharmacokinetics of single doses of doxylamine succinate following intranasal, oral and intravenous administration in rats.
Topics: Administration, Intranasal; Administration, Oral; Animals; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Doxylamine; Histamine H1 Antagonists; Injections, Intravenous; Male; Nasal Mucosa; Rats; Rats, Sprague-Dawley | 2002 |
[Clinical and experimental study of the antihistaminic activity of doxylamine succinate].
Topics: Doxylamine; Histamine H1 Antagonists; Humans | 1960 |
[Clinical and therapeutic study of doxylamine succinate, a new synthetic antihistaminic].
Topics: Anti-Allergic Agents; Doxylamine; Histamine H1 Antagonists; Hypersensitivity | 1959 |
[Clinical study of doxylamine succinate in pediatrics. (100 cases)].
Topics: Anti-Allergic Agents; Doxylamine; Histamine H1 Antagonists; Humans; Pediatrics; Succinates | 1962 |
[SYMPTOMATIC TREATMENT OF COUGH WITH PHOLCO-MEREPRINE SYRUP].
Topics: Anti-Allergic Agents; Antitussive Agents; Benzoates; Child; Cough; Doxylamine; Expectorants; Histamine H1 Antagonists; Humans | 1963 |
Differential protonation and dynamic structure of doxylamine succinate in solution using 1H and 13C NMR.
Topics: Carbon Isotopes; Doxylamine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Protons; Solutions | 2004 |
Separation of cold medicine ingredients using a precise MEKC method at elevated pH.
Topics: Acetaminophen; Buffers; Chromatography, Micellar Electrokinetic Capillary; Common Cold; Dextromethorphan; Doxylamine; Drug Combinations; Ephedrine; Excipients; Hydrogen-Ion Concentration; Reproducibility of Results; Sodium Dodecyl Sulfate | 2007 |
Clinical observations with decapryn; a new antihistaminic compound.
Topics: Doxylamine; Histamine Antagonists | 1948 |
Chronic toxicity studies on decapryn cussinate (2-[alpha-(2-dimethylaminoethoxy)-alpha-methylbenzyl]-pyridine succinate.
Topics: Doxylamine; Pyridines; Succinic Acid | 1948 |
Studies on the metabolism of 2-[ alpha-(2-dimethylaminoethoxy)-alpha-methylbenzyl]-pyridine succinate (decapryn succinate).
Topics: Doxylamine; Humans; Pyridines; Succinic Acid | 1948 |
Histamine antagonists; a new antihistaminic drug, 2-[alpha-(2-dimethylaminoethoxy)-alpha-methylbenzyl]-pyridine succinate (decapryn succinate); experimental and clinical results.
Topics: Doxylamine; Histamine; Histamine Antagonists; Humans; Pyridines; Succinic Acid | 1948 |
The clinical evaluation of a new histamine antagonist, decapryn.
Topics: Anti-Allergic Agents; Doxylamine; Histamine; Histamine Antagonists; Humans | 1948 |
Syndrome of inappropriate antidiuresis in doxylamine overdose.
Topics: Aged; Dose-Response Relationship, Drug; Doxylamine; Drug Overdose; Female; Glasgow Coma Scale; Humans; Hypnotics and Sedatives; Hyponatremia; Inappropriate ADH Syndrome; Saline Solution, Hypertonic; Sleep Initiation and Maintenance Disorders | 2012 |
Development and validation of a generic high-performance liquid chromatography for the simultaneous separation and determination of six cough ingredients: Robustness study on core-shell particles.
Topics: Acetaminophen; Antitussive Agents; Chromatography, High Pressure Liquid; Dextromethorphan; Doxylamine; Ephedrine; Guaifenesin; Humans; Phenylephrine | 2016 |
Advanced spectrophotometric chemometric methods for resolving the binary mixture of doxylamine succinate and pyridoxine hydrochloride.
Topics: Calibration; Doxylamine; Drug Compounding; Least-Squares Analysis; Multivariate Analysis; Pyridoxine; Spectrophotometry | 2018 |
Drug updates and approvals: 2018 in review.
Topics: Adenine; Alanine; Amides; Aminophenols; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzodioxoles; Clonidine; Doxylamine; Drug Approval; Emtricitabine; Heterocyclic Compounds, 3-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Indoles; Piperazines; Pyridones; Pyridoxine; Quinolones; Tenofovir; United States; United States Food and Drug Administration | 2018 |
Doxylamine succinate overdose: Slurred speech and visual hallucination.
Topics: Adolescent; Cholinesterase Inhibitors; Doxylamine; Drug Overdose; Female; Hallucinations; Histamine H1 Antagonists; Humans; Physostigmine; Speech; Speech Disorders | 2018 |
Harnessing of Doxylamine Succinate/Pyridoxine Hydrochloride-Dual Laden Bilosomes as a Novel Combinatorial Nanoparadigm for Intranasal Delivery: In Vitro Optimization and In Vivo Pharmacokinetic Appraisal.
Topics: Administration, Intranasal; Animals; Biological Availability; Doxylamine; Drug Delivery Systems; Gels; Particle Size; Pyridoxine; Rats | 2022 |
Chemometric Quality Assessment of Doxylamine Succinate With Its Degradation Product: Implementation of Two Predictive Models on UV-Spectrophotometric Data of Anti-Emetic Binary Mixture.
Topics: Antiemetics; Calibration; Chemometrics; Doxylamine; Least-Squares Analysis; Spectrophotometry; Spectrophotometry, Ultraviolet | 2022 |