doxorubicin hydrochloride and fluorouracil

doxorubicin hydrochloride has been researched along with fluorouracil in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.76)18.2507
2000's2 (9.52)29.6817
2010's15 (71.43)24.3611
2020's3 (14.29)2.80

Authors

AuthorsStudies
Barrero, AF; Cabrera, E; Chahboun, R; Cortés, M; Lara, M; Manzaneda, EA; Rivas, AR1
Banskota, AH; Kadota, S; Saiki, I; Tezuka, Y; Tran, QK; Tran, QL1
Banskota, AH; Kadota, S; Matsushige, K; Midorikawa, K; Tezuka, Y; Usia, T1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, K; Chen, Q; Chen, Z; Ding, J; Huang, H; Jiang, H; Ku, X; Li, M; Lin, L; Liu, H; Meng, L; Wang, X; Wang, Y; Zhu, C1
Kamiie, K; Kidachi, Y; Noshita, T; Ryoyama, K; Umetsu, H; Yamaguchi, H; Yu, T1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bhushan, S; Murthy, YL; Nagendra Sastry, Y; Pathania, AS; Suhasini, KP1
Arora, R; Arora, S; Chashoo, G; Chaudhry, A; Ishar, MP; Saxena, AK; Sharma, V1
Cao, D; Chen, L; Chen, Y; He, L; Li, D; Shao, M; Shen, M; Wang, F; Wang, T; Yan, W; Yang, Z; Zhou, Y1
Chen, S; Dai, H; Ge, S; Guo, J; Huang, M; Ling, Y; Shi, Y; Sun, S; Yang, J1
Bai, M; Chen, GY; Han, CR; Huang, GL; Luo, YP; Niu, YY; Niu, ZG; Shao, TM; Zheng, CJ; Zhou, XM1
Cai, B; Cui, CB; Li, CW; Wang, N; Xu, LL; Zhu, HJ1
Dong, JY; Huang, G; Li, SS; Meng, QQ; Zhang, QJ; Zhao, HR; Zhu, BQ1
Dai, H; Ge, S; Huang, M; Li, Y; Ling, Y; Liu, J; Meng, C; Ming, G; Qian, J; Shi, Y; Wang, S; Yao, Y; Zhang, T; Zhang, Y1
Li, X; Lu, DD; Ma, JH; Peng, AH; Song, YJ; Xie, WD; Zhang, HY; Zheng, HB1
Chen, T; Chen, Y; Ding, Y; Ge, W; Li, S; Liu, Z; Wang, M; Zhang, Q; Zhang, X1
Chen, G; Huang, G; Zhou, S1
Al-Fadhli, AA; Khan, S; Tilvi, S1
Valipour, M1

Reviews

3 review(s) available for doxorubicin hydrochloride and fluorouracil

ArticleYear
Synthesis and anti-tumor activity of marine alkaloids.
    Bioorganic & medicinal chemistry letters, 2021, 06-01, Volume: 41

    Topics: Alkaloids; Antineoplastic Agents; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Neoplasms

2021
Discovery of cytotoxic natural products from Red Sea sponges: Structure and synthesis.
    European journal of medicinal chemistry, 2021, Aug-05, Volume: 220

    Topics: Animals; Antineoplastic Agents; Biological Products; Cell Proliferation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Porifera

2021
Recent advances of antitumor shikonin/alkannin derivatives: A comprehensive overview focusing on structural classification, synthetic approaches, and mechanisms of action.
    European journal of medicinal chemistry, 2022, May-05, Volume: 235

    Topics: Antineoplastic Agents; Apoptosis; Humans; Naphthoquinones; Neoplasms

2022

Other Studies

18 other study(ies) available for doxorubicin hydrochloride and fluorouracil

ArticleYear
Synthesis of 11,12-epoxydrim-8,12-en-11-ol, 11,12-diacetoxydrimane, and warburganal from (-)-sclareol.
    Journal of natural products, 1999, Volume: 62, Issue:11

    Topics: Animals; Antineoplastic Agents; Benzofurans; Diterpenes; Drug Screening Assays, Antitumor; Humans; Leukemia P388; Naphthalenes; Porifera; Sesquiterpenes; Structure-Activity Relationship; Tumor Cells, Cultured

1999
New spirostanol steroids and steroidal saponins from roots and rhizomes of Dracaena angustifolia and their antiproliferative activity.
    Journal of natural products, 2001, Volume: 64, Issue:9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Colonic Neoplasms; Doxorubicin; Fibrosarcoma; Humans; Liliaceae; Melanoma; Mice; Plant Roots; Plants, Medicinal; Rhizome; Sapogenins; Saponins; Spirostans; Tumor Cells, Cultured; Vietnam

2001
Constituents of Chinese propolis and their antiproliferative activities.
    Journal of natural products, 2002, Volume: 65, Issue:5

    Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Caffeic Acids; China; Chromatography, Thin Layer; Colonic Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; Free Radical Scavengers; Mice; Molecular Structure; Phenylethyl Alcohol; Picrates; Propolis; Spectrophotometry, Infrared; Tumor Cells, Cultured

2002
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A series of alpha-heterocyclic carboxaldehyde thiosemicarbazones inhibit topoisomerase IIalpha catalytic activity.
    Journal of medicinal chemistry, 2010, Apr-22, Volume: 53, Issue:8

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Aldehydes; Animals; Antigens, Neoplasm; Antineoplastic Agents; Biocatalysis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Hydrolysis; Iron Chelating Agents; Mice; Models, Molecular; Neoplasm Transplantation; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship; Thiosemicarbazones; Topoisomerase II Inhibitors

2010
Novel effects of glycyrrhetinic acid on the central nervous system tumorigenic progenitor cells: induction of actin disruption and tumor cell-selective toxicity.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:7

    Topics: Actins; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Central Nervous System; Genes, myc; Genes, ras; Glycyrrhetinic Acid; Humans; Mice; Neoplasms; Stem Cells; Transfection

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Synthesis, structure activity relationship and mode of action of 3-substitutedphenyl-1-(2,2,8,8-tetramethyl-3,4,9,10-tetrahydro-2H,8H-pyrano[2,3-f]chromen-6-yl)-propenones as novel anticancer agents in human leukaemia HL-60 cells.
    European journal of medicinal chemistry, 2013, Volume: 62

    Topics: Antineoplastic Agents; Benzopyrans; Caco-2 Cells; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chalcones; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; MCF-7 Cells; Molecular Structure; Structure-Activity Relationship

2013
β-Ionone derived apoptosis inducing endoperoxides; Discovery of potent leads for anticancer agents.
    European journal of medicinal chemistry, 2014, Nov-24, Volume: 87

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetinae; Cricetulus; DNA; Drug Design; Humans; Intracellular Space; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Norisoprenoids; Peroxides; Reactive Oxygen Species

2014
Design, synthesis and biological evaluation of 4-anilinoquinoline derivatives as novel potent tubulin depolymerization agents.
    European journal of medicinal chemistry, 2017, Sep-29, Volume: 138

    Topics: Aniline Compounds; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Docking Simulation; Molecular Structure; Polymerization; Quinolines; Structure-Activity Relationship; Tubulin

2017
Development of novel bis-pyrazole derivatives as antitumor agents with potent apoptosis induction effects and DNA damage.
    European journal of medicinal chemistry, 2018, Jan-01, Volume: 143

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cells, Cultured; DNA Damage; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Liver Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Pyrazoles; Structure-Activity Relationship

2018
Penicilindoles A-C, Cytotoxic Indole Diterpenes from the Mangrove-Derived Fungus Eupenicillium sp. HJ002.
    Journal of natural products, 2018, 04-27, Volume: 81, Issue:4

    Topics: A549 Cells; Anti-Bacterial Agents; Cell Line, Tumor; Crystallography, X-Ray; Cytotoxins; Diterpenes; Eupenicillium; Fungi; HeLa Cells; Hep G2 Cells; Humans; Indoles; Magnetic Resonance Spectroscopy; Penicillium; Rhizophoraceae

2018
Four new antitumor metabolites isolated from a mutant 3-f-31 strain derived from Penicillium purpurogenum G59.
    European journal of medicinal chemistry, 2018, Oct-05, Volume: 158

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Products; Cell Line, Tumor; HCT116 Cells; Humans; Mice; Models, Molecular; Mutation; Neoplasms; Penicillium

2018
Discovery and synthesis of sulfur-containing 6-substituted 5,8-dimethoxy-1,4-naphthoquinone oxime derivatives as new and potential anti-MDR cancer agents.
    European journal of medicinal chemistry, 2019, Mar-01, Volume: 165

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Naphthoquinones; Oximes; Structure-Activity Relationship; Sulfur

2019
Excellent antitumor and antimetastatic activities based on novel coumarin/pyrazole oxime hybrids.
    European journal of medicinal chemistry, 2019, Mar-15, Volume: 166

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Coumarins; Epithelial-Mesenchymal Transition; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Oximes; Pyrazoles; Structure-Activity Relationship; Transforming Growth Factor beta1

2019
Strepantibins A-C: Hexokinase II Inhibitors from a Mud Dauber Wasp Associated Streptomyces sp.
    Journal of natural products, 2019, 05-24, Volume: 82, Issue:5

    Topics: Animals; Antineoplastic Agents; Enzyme Inhibitors; Hep G2 Cells; Hexokinase; Humans; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Streptomyces; Wasps

2019
Design and synthesis of parthenolide and 5-fluorouracil conjugates as potential anticancer agents against drug resistant hepatocellular carcinoma.
    European journal of medicinal chemistry, 2019, Dec-01, Volume: 183

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Nucleus; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Liver Neoplasms; Molecular Structure; Sesquiterpenes; Structure-Activity Relationship; Tumor Cells, Cultured

2019