doxorubicin hydrochloride and etoposide

doxorubicin hydrochloride has been researched along with etoposide in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (2.33)	18.2507
2000's	2 (4.65)	29.6817
2010's	35 (81.40)	24.3611
2020's	5 (11.63)	2.80

Authors

Authors	Studies
Kuoh, CS; Lee, KH; Liou, MJ; Nagao, T; Teng, CM; Wu, TS	1
Choo, HY; Jung, MJ; Kim, MH; Kwon, Y; Lim, SY; Rhee, HK	1
Cho, HJ; Jung, MJ; Kwon, Y; Na, Y	1
Jahng, Y; Jung, MJ; Karki, R; Kwon, Y; Lee, ES; Na, Y; Nam, JM; Thapa, P; Thapa, U	1
Basnet, A; Cho, WJ; Choi, H; Choi, JH; Jahng, Y; Jeong, BS; Karki, R; Kwon, Y; Lee, CS; Lee, ES; Na, Y; Thapa, P; Yun, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Cho, HJ; Jung, MJ; Kim, J; Kwon, Y; Lee, ES; Na, Y; Woo, S	1
Cho, WJ; Choi, H; Choi, JH; Jeong, BS; Jung, MJ; Karki, R; Kwon, Y; Lee, ES; Na, Y; Nam, JM; Thapa, P; Yun, M	1
Cho, WJ; Jeong, TC; Kang, MJ; Karki, R; Kim, HL; Kwon, Y; Lee, ES; Na, Y; Nam, JM; Thapa, P	1
Kamiie, K; Kidachi, Y; Noshita, T; Ryoyama, K; Umetsu, H; Yamaguchi, H; Yu, T	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ha, EM; Kang, DH; Kwon, Y; Lee, CS; Lee, ES; Na, Y; Nam, JM; Woo, S	1
Ekins, S; Williams, AJ; Xu, JJ	1
Jain, N; Kalivendi, SV; Kamal, A; Kumar, BA; Mallareddy, A; Raju, P; Reddy, PV; Shaik, TB; Suresh, P; Tamboli, JR	1
Jun, KY; Jung, MJ; Kwon, Y; Lee, ES; Lee, EY; Lee, OH; Na, Y; Park Choo, HY	1
Chen, H; Chen, L; Li, T; Liu, D; Liu, J; Liu, Y; Lu, Y; Tang, X; Wang, X; Zhang, S; Zhao, M; Zuo, S	1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P	1
de Carvalho, JE; de Fatima Cepa Matos, M; de Oliveira Figueiredo, P; Garcez, FR; Garcez, WS; Perdomo, RT	1
Jee, JG; Jun, KY; Kadayat, TM; Karki, R; Kwon, Y; Lee, ES; Lee, JH; Park, C; Thapa, P	1
Chen, W; Li, Z; Lu, C; Shen, Y; Zhang, M	1
Bist, G; Kadayat, TM; Kwon, Y; Lee, ES; Magar, TB; Na, Y; Shin, S; Shrestha, A; Song, C; Thapa, P	1
Bist, G; Jun, KY; Kadayat, TM; Kwon, Y; Lee, ES; Magar, TB; Na, Y; Park, S; Shrestha, A	1
Bist, G; Jun, KY; Kadayat, TM; Karki, R; Kwon, Y; Lee, ES; Na, Y; Shin, S; Shrestha, A; Thapa Magar, TB	1
Abdel-Aziz, HA; Ahmad, P; Jun, KY; Kadi, AA; Kwon, Y; Rahman, AF; Woo, H	1
Hong, E; Jun, KY; Kwak, SY; Kwon, Y; Lee, ES; Na, Y; Park, S	1
Chen, F; Chen, Y; Lin, Y; Wang, J; Zhang, L; Zhang, Z	1
Bist, G; Jun, KY; Kadayat, TM; Kwon, Y; Lee, ES; Park, S; Shrestha, A; Thapa Magar, TB	1
Islam, MS; Kadi, AA; Kwon, Y; Park, S; Rahman, AF; Song, C	1
Jeon, KH; Kwak, SY; Kwon, Y; Na, Y; Yu, HB	1
Bist, G; Kadayat, TM; Kwon, Y; Lee, ES; Lee, HJ; Park, S; Shrestha, A; Thapa Magar, TB	2
Bist, G; Kwon, Y; Lee, ES; Park, S; Shrestha, A; Song, C; Thapa Magar, TB	1
Cho, WJ; Han, J; Jin, Y; Khadka, DB; Kwon, Y; Park, S	1
Jo, H; Kwon, Y; Lee, ES; Shrestha, A	1
Bist, G; Jo, H; Kadayat, TM; Katila, P; Kwon, Y; Lee, ES; Magar, TBT; Seo, SH; Shrestha, A	1
Cai, B; Cui, CB; Li, CW; Wang, N; Xu, LL; Zhu, HJ	1
Jang, HJ; Katila, P; Kwon, Y; Lee, ES; Park, S; Shrestha, A; Shrestha, R	1
Hwang, SY; Jeon, YH; Jeong, TC; Jo, H; Kadayat, TM; Katila, P; Kim, KS; Kim, SK; Koh, WS; Kwon, Y; Lee, ES; Nepal, MR; Noh, K; Park, S; Shrestha, A; Shrestha, R	1
Gao, Y; Lou, HX; Luan, XY; Xie, F; Xu, K	1
Chen, G; Huang, G; Zhou, S	1
Hwang, SY; Jeon, KH; Kadayat, TM; Katila, P; Kim, D; Kunwar, S; Kwon, Y; Lee, ES; Park, S	1
Bist, G; Hwang, SY; Jang, H; Jeon, KH; Kadayat, TM; Kim, S; Kunwar, S; Kwon, Y; Lee, ES; Park, S; Seo, M; Sheen, N; Shrestha, A	1
Hwang, SY; Jung, AR; Katila, P; Kunwar, S; Kwon, Y; Lee, ES; Man Kadayat, T	1

Reviews

1 review(s) available for doxorubicin hydrochloride and etoposide

Article	Year
Synthesis and anti-tumor activity of marine alkaloids. Bioorganic & medicinal chemistry letters, 2021, 06-01, Volume: 41 Topics: Alkaloids; Antineoplastic Agents; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Neoplasms	2021

Other Studies

42 other study(ies) available for doxorubicin hydrochloride and etoposide

Article	Year
Cytotoxic and antiplatelet aggregation principles from Aglaia elliptifolia. Journal of natural products, 1997, Volume: 60, Issue:6 Topics: Animals; Antineoplastic Agents, Phytogenic; Benzofurans; Drug Screening Assays, Antitumor; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Plant Extracts; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tumor Cells, Cultured	1997
Synthesis of isoquinolinone-based tetracycles as poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors. Bioorganic & medicinal chemistry, 2009, Nov-01, Volume: 17, Issue:21 Topics: Antineoplastic Agents; Cell Line, Tumor; DNA Damage; Enzyme Inhibitors; Heterocyclic Compounds, 4 or More Rings; Humans; Isoquinolines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinolones	2009
Oxiranylmethyloxy or thiiranylmethyloxy-azaxanthones and -acridone analogues as potential topoisomerase I inhibitors. Bioorganic & medicinal chemistry letters, 2009, Dec-01, Volume: 19, Issue:23 Topics: Acridines; Antineoplastic Agents; Aza Compounds; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Topoisomerase I Inhibitors; Xanthones	2009
2-Thienyl-4-furyl-6-aryl pyridine derivatives: synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study. Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Neoplasms; Pyrimidines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	2010
2,6-Dithienyl-4-furyl pyridines: Synthesis, topoisomerase I and II inhibition, cytotoxicity, structure-activity relationship, and docking study. Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1 Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Computer Simulation; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Humans; Pyridines; Structure-Activity Relationship; Thiophenes; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
New benzoxanthone derivatives as topoisomerase inhibitors and DNA cross-linkers. Bioorganic & medicinal chemistry, 2010, Volume: 18, Issue:3 Topics: Antineoplastic Agents; Benzene Derivatives; Cell Line, Tumor; Cell Proliferation; DNA; DNA Topoisomerases; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Neoplasms; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topoisomerase Inhibitors; Xanthones	2010
Synthesis of 2-(thienyl-2-yl or -3-yl)-4-furyl-6-aryl pyridine derivatives and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antineoplastic Agents; Cell Proliferation; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Molecular Structure; Pyridines; Stereoisomerism; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured	2010
Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of hydroxylated 2,4-diphenyl-6-aryl pyridines. Bioorganic & medicinal chemistry, 2010, May-01, Volume: 18, Issue:9 Topics: Antineoplastic Agents; Cell Line, Tumor; Cytotoxins; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Molecular Structure; Pyridines; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	2010
Novel effects of glycyrrhetinic acid on the central nervous system tumorigenic progenitor cells: induction of actin disruption and tumor cell-selective toxicity. European journal of medicinal chemistry, 2010, Volume: 45, Issue:7 Topics: Actins; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Central Nervous System; Genes, myc; Genes, ras; Glycyrrhetinic Acid; Humans; Mice; Neoplasms; Stem Cells; Transfection	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Synthesis and pharmacological evaluation of new methyloxiranylmethoxyxanthone analogues. European journal of medicinal chemistry, 2010, Volume: 45, Issue:9 Topics: Antineoplastic Agents; Cell Line, Tumor; Cross-Linking Reagents; DNA; DNA Topoisomerases, Type II; Humans; Topoisomerase II Inhibitors; Xanthones	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Synthesis of a new 4-aza-2,3-didehydropodophyllotoxin analogues as potent cytotoxic and antimitotic agents. Bioorganic & medicinal chemistry, 2011, Apr-01, Volume: 19, Issue:7 Topics: Antimitotic Agents; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Activation; Flow Cytometry; Humans; Podophyllotoxin; Structure-Activity Relationship; Tubulin	2011
Synthesis, biological evaluation, and molecular docking study of 3-(3'-heteroatom substituted-2'-hydroxy-1'-propyloxy) xanthone analogues as novel topoisomerase IIα catalytic inhibitor. European journal of medicinal chemistry, 2011, Volume: 46, Issue:6 Topics: Antigens, Neoplasm; Antineoplastic Agents; Biocatalysis; Cell Line, Tumor; Cell Survival; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; HL-60 Cells; Humans; Models, Molecular; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Topoisomerase II Inhibitors; Xanthones	2011
Synthesis of 4β-triazole-podophyllotoxin derivatives by azide-alkyne cycloaddition and biological evaluation as potential antitumor agents. European journal of medicinal chemistry, 2011, Volume: 46, Issue:9 Topics: Antineoplastic Agents; Azides; Cell Line, Tumor; Cyclization; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Podophyllotoxin; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Triazoles	2011
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22 Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship	2012
Further constituents of Galianthe thalictroides (Rubiaceae) and inhibition of DNA topoisomerases I and IIα by its cytotoxic β-carboline alkaloids. Bioorganic & medicinal chemistry letters, 2014, Mar-01, Volume: 24, Issue:5 Topics: Alkaloids; Animals; Antigens, Neoplasm; Cell Line, Tumor; Cell Survival; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Humans; Lactose; MCF-7 Cells; Mice; Oligopeptides; Plant Roots; Rubiaceae; Topoisomerase Inhibitors	2014
Synthesis, antitumor activity, and structure-activity relationship study of trihydroxylated 2,4,6-triphenyl pyridines as potent and selective topoisomerase II inhibitors. European journal of medicinal chemistry, 2014, Sep-12, Volume: 84 Topics: Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Molecular Docking Simulation; Molecular Structure; Neoplasms; Phenols; Pyridines; Structure-Activity Relationship; Topoisomerase II Inhibitors	2014
Design and synthesis of 2-phenylnaphthalenoids as inhibitors of DNA topoisomeraseIIα and antitumor agents. European journal of medicinal chemistry, 2014, Oct-30, Volume: 86 Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Mice; Mice, Nude; Molecular Structure; Naphthalenes; Neoplasms, Experimental; Quantitative Structure-Activity Relationship; Topoisomerase II Inhibitors; Tumor Cells, Cultured	2014
Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of 2-phenyl- or hydroxylated 2-phenyl-4-aryl-5H-indeno[1,2-b]pyridines. Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13 Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Humans; Hydroxylation; Inhibitory Concentration 50; Molecular Structure; Protein Binding; Pyridines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	2015
Effect of chlorine substituent on cytotoxic activities: Design and synthesis of systematically modified 2,4-diphenyl-5H-indeno[1,2-b]pyridines. Bioorganic & medicinal chemistry letters, 2016, Apr-01, Volume: 26, Issue:7 Topics: Antineoplastic Agents; Biphenyl Compounds; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Design; Female; Halogenation; HeLa Cells; Humans; Indenes; Pyridines; Structure-Activity Relationship; Topoisomerase Inhibitors	2016
A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study. European journal of medicinal chemistry, 2016, May-04, Volume: 113 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pyridines; Quantitative Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	2016
Design, synthesis, topoisomerase I & II inhibitory activity, antiproliferative activity, and structure-activity relationship study of pyrazoline derivatives: An ATP-competitive human topoisomerase IIα catalytic inhibitor. Bioorganic & medicinal chemistry, 2016, Apr-15, Volume: 24, Issue:8 Topics: Adenosine Triphosphate; Antigens, Neoplasm; Antineoplastic Agents; Binding, Competitive; Biocatalysis; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Pyrazoles; Structure-Activity Relationship; Topoisomerase Inhibitors	2016
Synthesis and biological evaluation of C1-O-substituted-3-(3-butylamino-2-hydroxy-propoxy)-xanthen-9-one as topoisomerase IIα catalytic inhibitors. European journal of medicinal chemistry, 2016, Nov-10, Volume: 123 Topics: Adenosine Triphosphate; Antigens, Neoplasm; Antineoplastic Agents; Binding Sites; Biocatalysis; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Humans; Topoisomerase II Inhibitors; Xanthones	2016
Design, synthesis and evaluation of the multidrug resistance-reversing activity of pyridine acid esters of podophyllotoxin in human leukemia cells. Bioorganic & medicinal chemistry letters, 2016, 09-15, Volume: 26, Issue:18 Topics: Cell Line, Tumor; Drug Design; Drug Resistance, Multiple; Esters; Humans; Inhibitory Concentration 50; Leukemia; MAP Kinase Signaling System; Podophyllotoxin; Pyridines	2016
Novel 2-aryl-4-(4'-hydroxyphenyl)-5H-indeno[1,2-b]pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors. European journal of medicinal chemistry, 2017, Jan-05, Volume: 125 Topics: Antigens, Neoplasm; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; Humans; Molecular Docking Simulation; Pyridines; Structure-Activity Relationship; Topoisomerase II Inhibitors	2017
Fluorescein hydrazones: A series of novel non-intercalative topoisomerase IIα catalytic inhibitors induce G1 arrest and apoptosis in breast and colon cancer cells. European journal of medicinal chemistry, 2017, Jan-05, Volume: 125 Topics: Animals; Antigens, Neoplasm; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Female; Fluorescein; G1 Phase Cell Cycle Checkpoints; Humans; Hydrazones; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	2017
Synthesis and topoisomerases inhibitory activity of heteroaromatic chalcones. Bioorganic & medicinal chemistry, 2016, 11-15, Volume: 24, Issue:22 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chalcones; DNA Topoisomerases; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Structure-Activity Relationship; Topoisomerase Inhibitors	2016
Rational design, synthesis, and evaluation of novel 2,4-Chloro- and Hydroxy-Substituted diphenyl Benzofuro[3,2-b]Pyridines: Non-intercalative catalytic topoisomerase I and II dual inhibitor. European journal of medicinal chemistry, 2017, Feb-15, Volume: 127 Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Biocatalysis; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Design; Humans; Pyridines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	2017
Dihydroxylated 2,6-diphenyl-4-chlorophenylpyridines: Topoisomerase I and IIα dual inhibitors with DNA non-intercalative catalytic activity. European journal of medicinal chemistry, 2017, Jun-16, Volume: 133 Topics: Antineoplastic Agents; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; Halogenation; Humans; Neoplasms; Pyridines; Topoisomerase II Inhibitors	2017
2-Chlorophenyl-substituted benzofuro[3,2-b]pyridines with enhanced topoisomerase inhibitory activity: The role of the chlorine substituent. Bioorganic & medicinal chemistry letters, 2017, 08-01, Volume: 27, Issue:15 Topics: Antineoplastic Agents; Benzofurans; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Halogenation; Humans; Neoplasms; Pyridines; Topoisomerase Inhibitors	2017
Design, synthesis, and biological evaluation of 1,3-diarylisoquinolines as novel topoisomerase I catalytic inhibitors. European journal of medicinal chemistry, 2018, Jan-01, Volume: 143 Topics: Antineoplastic Agents; Biocatalysis; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Isoquinolines; Molecular Structure; Polymerization; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tubulin	2018
Design, synthesis, and structure-activity relationships of new benzofuro[3,2-b]pyridin-7-ols as DNA topoisomerase II inhibitors. Bioorganic & medicinal chemistry letters, 2018, 02-15, Volume: 28, Issue:4 Topics: Antineoplastic Agents; Benzofurans; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; Drug Design; Drug Screening Assays, Antitumor; Etoposide; Humans; Molecular Structure; Pyridines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	2018
Synthesis and SAR study of new hydroxy and chloro-substituted 2,4-diphenyl 5H-chromeno[4,3-b]pyridines as selective topoisomerase IIα-targeting anticancer agents. Bioorganic & medicinal chemistry, 2018, 05-01, Volume: 26, Issue:8 Topics: Antineoplastic Agents; Benzopyrans; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; HeLa Cells; Humans; Protein Binding; Pyridines; Structure-Activity Relationship; Topoisomerase II Inhibitors	2018
Four new antitumor metabolites isolated from a mutant 3-f-31 strain derived from Penicillium purpurogenum G59. European journal of medicinal chemistry, 2018, Oct-05, Volume: 158 Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Products; Cell Line, Tumor; HCT116 Cells; Humans; Mice; Models, Molecular; Mutation; Neoplasms; Penicillium	2018
A new phenolic series of indenopyridinone as topoisomerase inhibitors: Design, synthesis, and structure-activity relationships. Bioorganic & medicinal chemistry, 2018, 10-01, Volume: 26, Issue:18 Topics: Antineoplastic Agents; Cell Line; Cell Proliferation; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Indenes; Molecular Structure; Phenols; Pyridones; Structure-Activity Relationship; Topoisomerase Inhibitors	2018
Discovery and Biological Evaluations of Halogenated 2,4-Diphenyl Indeno[1,2- Journal of medicinal chemistry, 2019, 09-12, Volume: 62, Issue:17 Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Breast Neoplasms; Cell Proliferation; Cell Survival; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Female; Humans; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred ICR; Microwaves; Molecular Structure; Pyridines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tumor Cells, Cultured	2019
Cytotoxic Heptaketides from the Endolichenic Fungus Journal of natural products, 2020, 05-22, Volume: 83, Issue:5 Topics: A549 Cells; Antineoplastic Agents; Ascomycota; Cell Line, Tumor; Crystallography, X-Ray; DNA Damage; Humans; Lichens; Molecular Structure; Polyketides	2020
Discovery of a 2,4-diphenyl-5,6-dihydrobenzo(h)quinolin-8-amine derivative as a novel DNA intercalating topoisomerase IIα poison. European journal of medicinal chemistry, 2021, Dec-15, Volume: 226 Topics: Amines; Antineoplastic Agents; Cell Proliferation; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tumor Cells, Cultured	2021
Identification of new halogen-containing 2,4-diphenyl indenopyridin-5-one derivative as a boosting agent for the anticancer responses of clinically available topoisomerase inhibitors. European journal of medicinal chemistry, 2022, Jan-05, Volume: 227 Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Halogens; Humans; Indenes; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Poly-ADP-Ribose Binding Proteins; Pyridones; Structure-Activity Relationship; Topoisomerase Inhibitors; Tumor Cells, Cultured	2022
Topoisomerase IIα inhibitory and antiproliferative activity of dihydroxylated 2,6-diphenyl-4-fluorophenylpyridines: Design, synthesis, and structure-activity relationships. Bioorganic & medicinal chemistry letters, 2022, 03-15, Volume: 60 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Hydroxylation; Molecular Structure; Poly-ADP-Ribose Binding Proteins; Structure-Activity Relationship; Topoisomerase II Inhibitors	2022