doxorubicin hydrochloride and colchicine

doxorubicin hydrochloride has been researched along with colchicine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.88)29.6817
2010's12 (70.59)24.3611
2020's4 (23.53)2.80

Authors

AuthorsStudies
Baasner, S; Böhm, KJ; Gerlach, M; Günther, EG; Müller, K; Prinz, H; Schmidt, P; Unger, E; Zuse, A1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Baasner, S; Böhm, KJ; Gerlach, M; Günther, EG; Müller, K; Nickel, HC; Prinz, H; Schmidt, P; Unger, E1
Böhm, KJ; Müller, K; Prinz, H; Surkau, G1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Cao, D; Chen, L; Li, L; Liu, L; Ma, L; Tang, M; Wang, F; Wang, G; Wang, J; Wen, J; Wu, W; Xiang, M; Xiang, W; Yang, J; Yang, Z; You, J; Zhang, R; Zhu, J1
Bai, P; Cao, D; Chen, L; Lei, L; Liu, Y; Ma, B; Ma, L; Tang, M; Wang, C; Wang, F; Wang, T; Wang, X; Xu, B; Yan, W; Yang, T; Yang, Z; Zhou, Y1
Aghaee, E; Böhm, KJ; Ghasemi, JB; Ivanov, I; Müller, K; Prinz, H; Ridder, AK; Vogel, K1
Cao, D; Chen, L; Chen, Y; He, L; Li, D; Shao, M; Shen, M; Wang, F; Wang, T; Yan, W; Yang, Z; Zhou, Y1
Bai, P; Chen, L; Hu, M; Li, Y; Tang, M; Yan, W; Yang, J; Yang, Z1
Ai, W; Bao, N; Chen, H; Li, S; Li, W; Wang, S1
Han, L; Huang, X; Jin, X; Li, X; Liang, B; Ouyang, F; Xu, Y; Yan, J; Zhan, M; Zhang, Q1
Bai, P; Chen, L; Fu, S; Han, K; He, W; Li, J; Li, Y; Liu, J; Liu, Y; Shi, M; Tang, M; Xie, L; Yan, W; Yang, J; Yang, Z; Ye, H; Zhang, C; Zhu, Z1
Li, X; Lin, H; OuYang, F; Pang, Y; Yan, J; Zhang, W; Zhou, J1
Valipour, M1

Reviews

1 review(s) available for doxorubicin hydrochloride and colchicine

ArticleYear
Recent advances of antitumor shikonin/alkannin derivatives: A comprehensive overview focusing on structural classification, synthetic approaches, and mechanisms of action.
    European journal of medicinal chemistry, 2022, May-05, Volume: 235

    Topics: Antineoplastic Agents; Apoptosis; Humans; Naphthoquinones; Neoplasms

2022

Other Studies

16 other study(ies) available for doxorubicin hydrochloride and colchicine

ArticleYear
Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Journal of medicinal chemistry, 2007, Nov-29, Volume: 50, Issue:24

    Topics: Anthracenes; Cell Cycle; Cell Line, Tumor; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Naphthalenes; Nocodazole; Podophyllotoxin; Structure-Activity Relationship; Thiophenes; Tubulin; Tubulin Modulators

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Synthesis, antiproliferative activity and inhibition of tubulin polymerization by 1,5- and 1,8-disubstituted 10H-anthracen-9-ones bearing a 10-benzylidene or 10-(2-oxo-2-phenylethylidene) moiety.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:8

    Topics: Anthracenes; Antineoplastic Agents; Benzylidene Compounds; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Protein Multimerization; Protein Structure, Quaternary; Tubulin

2010
Synthesis, antiproliferative activity and inhibition of tubulin polymerization by anthracenone-based oxime derivatives.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:8

    Topics: Anthracenes; Antineoplastic Agents; Cell Proliferation; Humans; Inhibitory Concentration 50; K562 Cells; Oximes; Protein Multimerization; Protein Structure, Quaternary; Tubulin

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Synthesis and biological evaluation of novel millepachine derivatives as a new class of tubulin polymerization inhibitors.
    Journal of medicinal chemistry, 2014, Oct-09, Volume: 57, Issue:19

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chalcones; Drug Resistance, Multiple; Fluorescent Antibody Technique; Hep G2 Cells; Humans; Mice, Inbred BALB C; Structure-Activity Relationship; Tubulin Modulators; Xenograft Model Antitumor Assays

2014
Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors.
    Journal of medicinal chemistry, 2016, 06-23, Volume: 59, Issue:12

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; Coumarins; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Polymerization; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured; Wound Healing

2016
N-Heterocyclic (4-Phenylpiperazin-1-yl)methanones Derived from Phenoxazine and Phenothiazine as Highly Potent Inhibitors of Tubulin Polymerization.
    Journal of medicinal chemistry, 2017, 01-26, Volume: 60, Issue:2

    Topics: Alkylating Agents; Antineoplastic Agents; Ethylenediamines; G2 Phase Cell Cycle Checkpoints; Humans; K562 Cells; Molecular Docking Simulation; Oxazines; Phenothiazines; Piperazines; Polymerization; Quantitative Structure-Activity Relationship; Tubulin; Tubulin Modulators

2017
Design, synthesis and biological evaluation of 4-anilinoquinoline derivatives as novel potent tubulin depolymerization agents.
    European journal of medicinal chemistry, 2017, Sep-29, Volume: 138

    Topics: Aniline Compounds; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Docking Simulation; Molecular Structure; Polymerization; Quinolines; Structure-Activity Relationship; Tubulin

2017
Discovery of novel β-carboline/acylhydrazone hybrids as potent antitumor agents and overcome drug resistance.
    European journal of medicinal chemistry, 2018, May-25, Volume: 152

    Topics: Animals; Antineoplastic Agents; Carbolines; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Hydrazones; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship

2018
The inhibitory effect of kokusaginine on the growth of human breast cancer cells and MDR-resistant cells is mediated by the inhibition of tubulin assembly.
    Bioorganic & medicinal chemistry letters, 2018, 08-01, Volume: 28, Issue:14

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dictamnus; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Furans; Humans; MCF-7 Cells; Molecular Structure; Quinolines; Structure-Activity Relationship; Tubulin

2018
Structure modification and biological evaluation of indole-chalcone derivatives as anti-tumor agents through dual targeting tubulin and TrxR.
    European journal of medicinal chemistry, 2022, Jan-05, Volume: 227

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chalcones; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Indoles; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Structure-Activity Relationship; Thioredoxin-Disulfide Reductase; Tubulin; Tubulin Modulators

2022
Structure-Based Design and Synthesis of N-Substituted 3-Amino-β-Carboline Derivatives as Potent αβ-Tubulin Degradation Agents.
    Journal of medicinal chemistry, 2022, 02-10, Volume: 65, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Binding Sites; Carbolines; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; G2 Phase Cell Cycle Checkpoints; Humans; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms; Protein Binding; Rats; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Xenograft Model Antitumor Assays

2022
Discovery of a Novel Stilbene Derivative as a Microtubule Targeting Agent Capable of Inducing Cell Ferroptosis.
    Journal of medicinal chemistry, 2022, 03-24, Volume: 65, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Ferroptosis; Humans; Microtubules; Neoplasms; Stilbenes

2022