doxifluridine has been researched along with uridine in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (45.00) | 18.7374 |
| 1990's | 6 (30.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Senderoff, RI; Smith, DR; Sokoloski, TD; Weber, PA | 1 |
| Inaba, M; Mitsuhashi, J; Ozawa, S | 1 |
| Kumar, AM; Nayak, R | 1 |
| Armstrong, RD; Cadman, EC; Takimoto, CH; Tan, YY | 1 |
| Armstrong, RD; Cadman, EC; Takimoto, CH | 1 |
| Hara, Y; Karube, Y; Kono, A; Matsushima, Y; Sugata, S | 1 |
| Lankelma, J; Laurensse, EJ; Leyva, A; Peters, GJ; Pinedo, HM; van Dijk, J; van Groeningen, C | 1 |
| Au, JL; Bramer, SL; Wientjes, MG | 1 |
| Au, JL; Luccioni, CM; Rustum, YM; Wientjes, MG | 1 |
| Cadman, E; Grant, S | 1 |
| Armstrong, RD; Connolly, KM; Diasio, RB; Kaplan, AM | 1 |
| Fukuoka, K; Ishitsuka, H; Itoga, A; Maruyama, HB; Miwa, M; Takemoto, K | 1 |
| el Kouni, MH; el Kouni, MM; Naguib, FN | 1 |
| Eda, H; Fujimoto, K; Ishikawa, T; Ishitsuka, H; Ohiwa, T; Tanaka, Y; Tatsuno, K; Watanabe, S | 1 |
| Nakagawa, T; Sawai, Y; Yamaoka, K | 1 |
| Cao, D; Pizzorno, G | 1 |
| Cricca, S; de Bruin, M; Laan, AC; Peters, GJ; Temmink, OH; Turksma, AW | 1 |
| Baek, IH; Kim, MS; Kwon, KI; Lee, BY | 1 |
| He, S; Jiang, Y; Pu, K; Xie, C | 1 |
1 review(s) available for doxifluridine and uridine
| Article | Year |
|---|---|
Uridine phosophorylase: an important enzyme in pyrimidine metabolism and fluoropyrimidine activation.
Topics: Animals; Antimetabolites, Antineoplastic; Floxuridine; Fluorouracil; Gene Expression Regulation, Enzymologic; Humans; Neoplasms; Pyrimidines; Uridine; Uridine Phosphorylase | 2004 |
19 other study(ies) available for doxifluridine and uridine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Evaluation of antiproliferative agents using a cell-culture model.
Topics: Animals; Bleomycin; Cell Count; Cell Division; Cells, Cultured; Colorimetry; Cricetinae; Cytarabine; Drug Evaluation, Preclinical; Floxuridine; Fluorouracil; Tetrazolium Salts; Thiazoles; Time Factors; Uridine | 1990 |
Kinetic analysis of 5-fluorouracil action against various cancer cells.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Colonic Neoplasms; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Humans; Kidney Neoplasms; Leukemia P388; Mice; RNA, Ribosomal; S Phase; Time Factors; Uridine | 1990 |
Glycosidic bond cleavage of 5-fluoro-2'-deoxyuridine and 5-fluorouridine by amino acyl-tRNA synthetases.
Topics: Animals; Chromatography, Thin Layer; Cytoplasm; Floxuridine; Glycoside Hydrolases; Glycosides; Hydrolysis; Liver; Lysine-tRNA Ligase; Rats; Rats, Inbred Strains; Uridine | 1990 |
Correlation between ribosomal RNA production and RNA-directed fluoropyrimidine cytotoxicity.
Topics: Animals; Cell Nucleus; Cell Survival; Cytoplasm; DNA; Floxuridine; Fluorouracil; Mice; RNA; RNA, Messenger; RNA, Ribosomal; Sarcoma 180; Uridine | 1987 |
Precursor-dependent differences in the incorporation of fluorouracil in RNA.
Topics: Animals; Cell Survival; Cells, Cultured; Floxuridine; Fluorouracil; Mice; RNA, Neoplasm; Sarcoma, Experimental; Thymidine; Uridine | 1986 |
Partial purification of a thymidine phosphorylase from human gastric cancer.
Topics: Floxuridine; Humans; In Vitro Techniques; Pentosyltransferases; Stomach Neoplasms; Thymidine; Thymidine Phosphorylase; Uridine | 1986 |
Toxicity and antitumor effect of 5-fluorouracil and its rescue by uridine.
Topics: Animals; Body Temperature Regulation; Carcinoma; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Floxuridine; Fluorouracil; Hematopoiesis; Leukocyte Count; Mice; Uridine | 1986 |
Effect of uridine coadministration on 5'-deoxy-5-fluorouridine disposition in rats.
Topics: Administration, Oral; Animals; Biological Availability; Biotransformation; Floxuridine; Injections, Intravenous; Intestinal Absorption; Metabolic Clearance Rate; Rats; Rats, Inbred F344; Uridine | 1988 |
Reversed-phase ion-pair high-performance liquid chromatographic assay of 5-fluorouracil, 5'-deoxy-5-fluorouridine, their nucleosides, mono-, di-, and triphosphate nucleotides with a mixture of quaternary ammonium ions.
Topics: Chromatography, High Pressure Liquid; Deoxyuracil Nucleotides; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Isomerism; Structure-Activity Relationship; Uracil Nucleotides; Uridine | 1982 |
Modulation of 1-beta-D-arabinofuranosylcytosine metabolism and cytotoxicity in L1210 cells by fluoropyrimidine pretreatment.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cell Line; Cell Survival; Clone Cells; Cytarabine; Deoxyribonucleotides; Deoxyuridine; Drug Interactions; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Leukemia L1210; Mice; Uridine | 1982 |
Decreased immunosuppression associated with antitumor activity of 5-deoxy-5-fluorouridine compared to 5-fluorouracil and 5-fluorouridine.
Topics: Animals; Antineoplastic Agents; Cell Survival; Female; Floxuridine; Fluorouracil; Immunosuppression Therapy; Inflammation; Male; Mice; Mice, Inbred C57BL; Pyrans; Thioglycolates; Uridine | 1983 |
Role of uridine phosphorylase for antitumor activity of 5'-deoxy-5-fluorouridine.
Topics: Animals; Biotransformation; Floxuridine; Fluorouracil; Leukemia L1210; Male; Mice; Pentosyltransferases; Sarcoma 180; Tegafur; Thymidine; Uridine; Uridine Phosphorylase | 1980 |
Differences in activities and substrate specificity of human and murine pyrimidine nucleoside phosphorylases: implications for chemotherapy with 5-fluoropyrimidines.
Topics: Animals; Floxuridine; Fluorouracil; Humans; Liver; Mice; Placenta; Species Specificity; Substrate Specificity; Thymidine Phosphorylase; Uridine; Uridine Phosphorylase | 1993 |
Cytokines induce uridine phosphorylase in mouse colon 26 carcinoma cells and make the cells more susceptible to 5'-deoxy-5-fluorouridine.
Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Cytokines; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Fibroblast Growth Factor 2; Floxuridine; Fluorouracil; Interferon-gamma; Interleukin-1; Mice; RNA, Neoplasm; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Uridine; Uridine Phosphorylase | 1993 |
Effect of coadministered uridine on intestinal first-pass metabolism of 5'-deoxy-5-fluorouridine in conscious rats--an evaluation by method of portal-systemic concentration difference.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Arteries; Drug Interactions; Floxuridine; Fluorouracil; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Portal System; Portal Vein; Rats; Rats, Wistar; Uridine | 1998 |
Activity and substrate specificity of pyrimidine phosphorylases and their role in fluoropyrimidine sensitivity in colon cancer cell lines.
Topics: Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhibitors; Floxuridine; Humans; Kinetics; Pyrimidines; Substrate Specificity; Thymidine Phosphorylase; Uridine; Uridine Phosphorylase | 2007 |
Pharmacokinetic analysis of doxifluridine and its metabolites, 5-fluorouracil and 5-fluorouridine, after oral administration in beagle dogs.
Topics: Administration, Oral; Algorithms; Animals; Antimetabolites, Antineoplastic; Area Under Curve; Capsules; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Dogs; Floxuridine; Fluorouracil; Indicators and Reagents; Mass Spectrometry; Tandem Mass Spectrometry; Uridine | 2013 |
An Organic Afterglow Protheranostic Nanoassembly.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Dimerization; Drug Delivery Systems; Floxuridine; Hydrogen Peroxide; Infrared Rays; Luminescent Agents; Mice; Nanoparticles; Neoplasms; Polyethylene Glycols; Prodrugs; Theranostic Nanomedicine; Tissue Distribution; Tumor Microenvironment; Uridine | 2019 |