doxepin and nortriptyline

doxepin has been researched along with nortriptyline in 67 studies

Research

Studies (67)

TimeframeStudies, this research(%)All Research%
pre-199035 (52.24)18.7374
1990's10 (14.93)18.2507
2000's12 (17.91)29.6817
2010's8 (11.94)24.3611
2020's2 (2.99)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Chiang, GH; Unger, SH1
Booth, RG; Brown, RL; Bucholtz, EC; Tropsha, A; Wyrick, SD1
Medina-Hernández, MJ; Quiñones-Torrelo, C; Sagrado, S; Villanueva-Camañas, RM1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Hajjo, R; Roth, BL; Setola, V; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hollister, LE1
Richelson, E1
Levine, RM; Maickel, RP; Spaulding, JH; Zabik, JE1
Dorrity, F; Jobson, K; Linnoila, M1
Dujovne, CA; Ueda, I; Yasuhara, H1
Hedgepeth, EM; Lowell, SH; Rhoads, JM1
Biggs, JT; Petit, JM; Spiker, DG; Ziegler, VE1
Leppäluoto, J; Linnoila, M; Ranta, T; Seppälä, T1
Lohmann, HJ; Miles, DG; Proelss, HF1
Connor, JN; Johnson, GF; Solomon, HM1
Burrows, GD; Davies, B; Hunt, D; Scoggins, BA; Sloman, JG; Vohra, J1
Burrows, GD; Sloman, G; Vohra, J1
Elonen, E; Linnoila, M; Mäki, M; Mattila, MJ; Seppälä, T1
Burrows, G; Hunt, D; Sloman, G; Vohra, J1
Elonen, E; Mattila, MJ1
Elonen, E; Linnoila, M; Lukkari, I; Mattila, MJ1
Slovis, CM; Smith, BA; Wrenn, K1
Dalack, GW; Glassman, AH; Roose, SP1
Small, GW1
Balon, R; Berchou, R; Ortiz, A; Pohl, R; Rainey, JM; Yeragani, VK1
Burns, EA; Perry, PJ; True, BL1
Tuomisto, J1
Bareggi, SR; Bonaccorsi, A; Franco, R; Garattini, S; Morselli, PL; Mundo, AS; Riva, E1
Elonen, E; Mattila, MJ; Saarnivaara, L1
Elonen, E1
Pigott, PV1
Mattila, MJ; Saarnivaara, L1
Beierle, FA; Hubbard, RW1
Asnis, GM; Endicott, J; Halbreich, U; Nathan, RS; Novacenko, H; Ostrow, L; Sachar, EJ1
Amsterdam, J; Brunswick, D; Mendels, J1
Lyskowksi, J; Nasrallah, HA; Schroeder, D1
Friedel, RO1
Charette, C; Midha, KK1
Kabra, PM; Mar, NA; Marton, LJ1
Bannister, SJ; Dolan, JW; Snyder, LR; van der Wal, S1
Drummer, OH; King, CV; McIntyre, IM; Skafidis, S1
Jamali, F; Mehvar, R1
Hubbard, JW; McKay, G; Midha, KK; Rawson, MJ1
Hubbard, JW; Midha, KK; Rawson, MJ2
Manju, B; Revanasiddappa, HD1
Ahokas, JT; Ching, MS; Ghabrial, H; Haritos, VS1
Golding, M; Hatsukami, DK; Jamerson, BD; Kotlyar, M1
Cahoon, EE; Gerner, P; Sudoh, Y; Wang, GK1
Amitai, Y; Frischer, H1
Calabuig-Hernández, S; García-Alvarez-Coque, MC; Peris-García, E; Ruiz-Angel, MJ1
Caldara, M; Marmiroli, N1
Deckert, J; Hommers, LG; Menke, A; Samanski, L; Scherf-Clavel, M; Unterecker, S1
Deckert, J; Hommers, L; Menke, A; Scherf-Clavel, M; Unterecker, S; Zebner, J1
Augusti, R; Nascentes, CC; Oliveira, FM; Scheel, GL; Tarley, CRT1

Reviews

10 review(s) available for doxepin and nortriptyline

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Tricyclic antidepressants (first of two parts).
    The New England journal of medicine, 1978, Nov-16, Volume: 299, Issue:20

    Topics: Aged; Amines; Amitriptyline; Antidepressive Agents, Tricyclic; Chemical Phenomena; Chemistry; Child; Depression; Desipramine; Doxepin; Humans; Imipramine; Kinetics; Neurotransmitter Agents; Nortriptyline; Protriptyline

1978
Tricyclic antidepressants for medically ill geriatric patients.
    The Journal of clinical psychiatry, 1989, Volume: 50 Suppl

    Topics: Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Doxepin; Geriatrics; Humans; Nortriptyline

1989
The clinical application of tricyclic antidepressant pharmacokinetics and plasma levels.
    The American journal of psychiatry, 1980, Volume: 137, Issue:6

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Desipramine; Doxepin; Heart; Humans; Imipramine; Nortriptyline; Protriptyline

1980
Bioequivalence of chiral drugs. Stereospecific versus non-stereospecific methods.
    Clinical pharmacokinetics, 1997, Volume: 33, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Area Under Curve; Computer Simulation; Disopyramide; Doxepin; Drug Interactions; Flurbiprofen; Food-Drug Interactions; Guidelines as Topic; Hydroxychloroquine; Ibuprofen; Nadolol; Nortriptyline; Propafenone; Stereoisomerism; Therapeutic Equivalency; Verapamil

1997
The impact of stereoisomerism in bioequivalence studies.
    Journal of pharmaceutical sciences, 1998, Volume: 87, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Doxepin; Flurbiprofen; Humans; Hydroxychloroquine; Ketoprofen; Nadolol; Nortriptyline; Propafenone; Stereoisomerism; Therapeutic Equivalency

1998
Bioequivalence: issues and options.
    Journal of pharmacokinetics and biopharmaceutics, 1997, Volume: 25, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Doxepin; Humans; Ketoprofen; Nortriptyline; Stereoisomerism; Therapeutic Equivalency

1997
Effect of nonnicotine pharmacotherapy on smoking behavior.
    Pharmacotherapy, 2001, Volume: 21, Issue:12

    Topics: Amphetamines; Bupropion; Clonidine; Doxepin; Humans; Naltrexone; Nortriptyline; Selective Serotonin Reuptake Inhibitors; Smoking Cessation

2001
The role of metabolites in bioequivalence.
    Pharmaceutical research, 2004, Volume: 21, Issue:8

    Topics: Area Under Curve; Biotransformation; Clinical Trials as Topic; Doxepin; Guidelines as Topic; Humans; Liver; Nortriptyline; Pharmaceutical Preparations; Pharmacokinetics; Therapeutic Equivalency; United States; United States Food and Drug Administration

2004

Trials

4 trial(s) available for doxepin and nortriptyline

ArticleYear
Plasma and erythrocyte levels of tricyclic antidepressants in depressed patients.
    The American journal of psychiatry, 1978, Volume: 135, Issue:5

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Biopharmaceutics; Clinical Trials as Topic; Depression; Desipramine; Doxepin; Erythrocytes; Humans; Imipramine; Middle Aged; Nortriptyline

1978
Effect of tricyclic antidepressants and alcohol in psychomotor skills related to driving.
    Clinical pharmacology and therapeutics, 1975, Volume: 17, Issue:5

    Topics: Adult; Amitriptyline; Analysis of Variance; Antidepressive Agents, Tricyclic; Attention; Automobile Driving; Blood Pressure; Choice Behavior; Clinical Trials as Topic; Dose-Response Relationship, Drug; Doxepin; Drug Interactions; Ethanol; Humans; Motor Skills; Nortriptyline; Reaction Time; Time Factors; Tyramine

1975
Sodium lactate infusions after treatment with tricyclic antidepressants: behavioral and physiological findings.
    Biological psychiatry, 1988, Volume: 24, Issue:7

    Topics: Antidepressive Agents, Tricyclic; Arousal; Clinical Trials as Topic; Desipramine; Double-Blind Method; Doxepin; Fear; Humans; Imipramine; Isoproterenol; Lactates; Lactic Acid; Nortriptyline; Panic; Psychological Tests

1988
A review of clinical studies with combinations of fluphenazine and nortriptyline.
    Current medical research and opinion, 1972, Volume: 1, Issue:1

    Topics: Amitriptyline; Anxiety; Central Nervous System; Clinical Trials as Topic; Depression; Diazepam; Doxepin; Drug Combinations; Fluphenazine; Heart Conduction System; Humans; Motor Activity; Nortriptyline; Perphenazine; Placebos; Psychiatric Status Rating Scales; Vision Disorders

1972

Other Studies

53 other study(ies) available for doxepin and nortriptyline

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship

1981
Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ligands; Models, Molecular; Pyrilamine; Radioligand Assay; Structure-Activity Relationship; Tetrahydronaphthalenes

1999
Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Enzyme Inhibitors; Histamine H1 Antagonists; Micelles; Models, Biological; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship

1999
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Chemocentric informatics approach to drug discovery: identification and experimental validation of selective estrogen receptor modulators as ligands of 5-hydroxytryptamine-6 receptors and as potential cognition enhancers.
    Journal of medicinal chemistry, 2012, Jun-28, Volume: 55, Issue:12

    Topics: Alzheimer Disease; Cell Line, Tumor; Cloning, Molecular; Cognition; Drug Discovery; Drug Evaluation, Preclinical; Genomics; Humans; Informatics; Ligands; Nootropic Agents; Quantitative Structure-Activity Relationship; Raloxifene Hydrochloride; Receptors, Serotonin; Reproducibility of Results; Selective Estrogen Receptor Modulators; Serotonin Antagonists; User-Computer Interface

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Tricyclic antidepressants and histamine H1 receptors.
    Mayo Clinic proceedings, 1979, Volume: 54, Issue:10

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Atropine; Benztropine; Cells, Cultured; Clozapine; Cyproheptadine; Desipramine; Doxepin; Haloperidol; Histamine H1 Antagonists; Hydroxyzine; Imipramine; Mice; Neoplasms, Experimental; Neuroblastoma; Nortriptyline; Protriptyline; Receptors, Histamine; Receptors, Histamine H1; Receptors, Muscarinic

1979
Interactions of tricyclic antidepressant drugs with deprivation-induced fluid consumption by rats.
    Neuropharmacology, 1977, Volume: 16, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Doxepin; Drinking Behavior; Fenclonine; Imipramine; Male; Methyltyrosines; Nortriptyline; Protriptyline; Rats; Water Deprivation

1977
Relationship between surface activity and toxicity to Chang liver cultures of tricyclic antidepressants.
    Pharmacology, 1979, Volume: 18, Issue:2

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Cells, Cultured; Clomipramine; Doxepin; Glucuronidase; Humans; Imipramine; L-Lactate Dehydrogenase; Liver; Nortriptyline; Surface Tension

1979
Hoarseness and aphonia as a side effect of tricyclic antidepressants.
    The American journal of psychiatry, 1979, Volume: 136, Issue:12

    Topics: Antidepressive Agents, Tricyclic; Aphonia; Doxepin; Hoarseness; Humans; Male; Middle Aged; Nortriptyline; Smoking

1979
Tricyclic antidepressant overdose: incidence of symptoms.
    JAMA, 1977, Jul-11, Volume: 238, Issue:2

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Doxepin; Electrocardiography; Heart; Humans; Imipramine; Nortriptyline

1977
Serum gonadotropin and TSH levels after tricyclic antidepressants in healthy males.
    Acta pharmacologica et toxicologica, 1977, Volume: 41, Issue:3

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Doxepin; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Nortriptyline; Secretory Rate; Thyrotropin

1977
High-performance liquid-chromatographic simultaneous determination of commonly used tricyclic antidepressants.
    Clinical chemistry, 1978, Volume: 24, Issue:11

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline

1978
Quantitation of amitriptyline and nortriptyline in human serum.
    Journal of chromatography, 1977, Jul-01, Volume: 143, Issue:4

    Topics: Amitriptyline; Chromatography, Gas; Dealkylation; Doxepin; Humans; Maprotiline; Nortriptyline

1977
Cardiac effects of different tricyclic antidepressant drugs.
    The British journal of psychiatry : the journal of mental science, 1976, Volume: 129

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Bundle of His; Doxepin; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Imipramine; Nortriptyline; Substance-Related Disorders

1976
Assessment of cardiovascular side effects of therapeutic doses of tricyclic anti-depressant drugs.
    Australian and New Zealand journal of medicine, 1975, Volume: 5, Issue:1

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Blood Pressure; Depression, Chemical; Doxepin; Electrocardiography; Female; Heart Conduction System; Heart Rate; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Physical Exertion; Stimulation, Chemical

1975
The effect of toxic and therapeutic doses of tricyclic antidepressant drugs on intracardiac conduction.
    European journal of cardiology, 1975, Volume: 3, Issue:3

    Topics: Antidepressive Agents, Tricyclic; Bundle of His; Doxepin; Electrocardiography; Heart Conduction System; Humans; Nortriptyline

1975
Cardiovascular effects of amitriptyline, nortriptyline, protriptyline, and doxepin in conscious rabbits after subacute pretreatment with protriptyline.
    Medical biology, 1975, Volume: 53, Issue:4

    Topics: Amitriptyline; Animals; Blood Pressure; Dibenzocycloheptenes; Doxepin; Electrocardiography; Heart Rate; Norepinephrine; Nortriptyline; Protriptyline; Rabbits; Tyramine

1975
Concentration of tricyclic antidepressants in plasma, heart and skeletal muscle after their intravenous infusion to anaesthetized rabbits.
    Acta pharmacologica et toxicologica, 1975, Volume: 37, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Doxepin; Infusions, Parenteral; Muscles; Myocardium; Nortriptyline; Protriptyline; Rabbits

1975
Profound alkalemia during treatment of tricyclic antidepressant overdose: a potential hazard of combined hyperventilation and intravenous bicarbonate.
    The American journal of emergency medicine, 1992, Volume: 10, Issue:6

    Topics: Adult; Aged; Alkalosis; Antidepressive Agents, Tricyclic; Bicarbonates; Critical Care; Doxepin; Drug Overdose; Female; Humans; Hyperventilation; Infusions, Intravenous; Male; Nortriptyline; Suicide, Attempted

1992
Tricyclics and heart failure.
    The American journal of psychiatry, 1991, Volume: 148, Issue:11

    Topics: Aged; Depressive Disorder; Doxepin; Heart Failure; Humans; Male; Myocardial Contraction; Nortriptyline; Stimulation, Chemical; Stroke Volume

1991
Profound hypoglycemia with the addition of a tricyclic antidepressant to maintenance sulfonylurea therapy.
    The American journal of psychiatry, 1987, Volume: 144, Issue:9

    Topics: Aged; Chlorpropamide; Depressive Disorder; Diabetes Complications; Diabetes Mellitus; Doxepin; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypoglycemia; Middle Aged; Nortriptyline; Tolazamide

1987
A new modification for studying 5-HT uptake by blood platelets: a re-evaluation of tricyclic antidepressants as uptake inhibitors.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:2

    Topics: Amitriptyline; Animals; Blood Platelets; Carbon Radioisotopes; Chlorpromazine; Desipramine; Dibenzazepines; Doxepin; Imipramine; In Vitro Techniques; Kinetics; Models, Biological; Nortriptyline; Promazine; Rabbits; Serotonin; Synaptosomes; Temperature; Trifluoperazine; Triflupromazine

1974
Relationships between tricyclic antidepressant concentrations, 1-3H-noradrenaline uptake and chronotropic effect in isolated rat atria.
    European journal of pharmacology, 1974, Volume: 28, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Carbon Radioisotopes; Chromatography, Thin Layer; Clomipramine; Dealkylation; Desipramine; Dose-Response Relationship, Drug; Doxepin; Drug Synergism; Female; Heart Atria; Heart Rate; Norepinephrine; Nortriptyline; Rats; Rats, Inbred Strains; Stimulation, Chemical; Time Factors; Tritium

1974
Cardiovascular effects of amitriptyline, nortriptyline, protriptyline and doxepin in conscious rabbits.
    European journal of pharmacology, 1974, Volume: 28, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Aorta; Blood Pressure; Depression, Chemical; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Doxepin; Drug Synergism; Electrocardiography; Heart Atria; Heart Rate; Hemodynamics; Muscle Contraction; Muscle, Smooth; Norepinephrine; Nortriptyline; Propylamines; Rabbits

1974
Correlation of the cardiotoxicity of tricyclic antidepressants to their membrane effects.
    Medical biology, 1974, Volume: 52, Issue:6

    Topics: Amitriptyline; Anesthesia, Local; Animals; Cell Membrane; Cornea; Depression, Chemical; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Doxepin; Electrocardiography; Erythrocytes; Heart Rate; Hemolysis; Male; Mice; Nortriptyline; Octanols; Propylamines; Rabbits; Stimulation, Chemical; Surface Tension

1974
Comparison of tricyclic antidepressants in rabbits: antinociception and potentiation of the noradrenaline pressor responses.
    Psychopharmacologia, 1974, Feb-27, Volume: 35, Issue:3

    Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Aorta; Blood Pressure; Chlorpromazine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Doxepin; Drug Synergism; Imipramine; In Vitro Techniques; Iprindole; Lithium; Morphine; Norepinephrine; Nortriptyline; Opipramol; Rabbits; Succinimides; Time Factors

1974
Liquid chromatographic separation of antidepressant drugs: I. Tricyclics.
    Therapeutic drug monitoring, 1983, Volume: 5, Issue:3

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Promazine; Protriptyline

1983
The dexamethasone suppression test in depressive illness: clinical correlates.
    Psychoneuroendocrinology, 1982, Volume: 7, Issue:4

    Topics: Depressive Disorder; Desipramine; Dexamethasone; Diagnosis, Differential; Double-Blind Method; Doxepin; Electroconvulsive Therapy; Female; Humans; Hydrocortisone; Imipramine; Male; Mianserin; Middle Aged; Nortriptyline; Phenelzine; Psychiatric Status Rating Scales; Selegiline

1982
TCA-induced mania: differences between switchers and nonswitchers.
    Biological psychiatry, 1982, Volume: 17, Issue:2

    Topics: Adult; Affective Disorders, Psychotic; Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Desipramine; Doxepin; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Protriptyline

1982
The relationship of therapeutic response to antidepressant plasma levels: an update.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:11 Pt 2

    Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Biological Availability; Depressive Disorder; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Patient Compliance; Protriptyline

1982
Radioimmunoassay for total doxepin and N-desmethyl doxepin in plasma.
    Communications in psychopharmacology, 1980, Volume: 4, Issue:1

    Topics: Animals; Cross Reactions; Dealkylation; Doxepin; Humans; Kinetics; Male; Nortriptyline; Rabbits; Radioimmunoassay; Time Factors

1980
Simultaneous liquid chromatographic analysis of amitriptyline, nortriptyline, imipramine, desipramine, doxepin, and nordoxepin.
    Clinica chimica acta; international journal of clinical chemistry, 1981, Apr-09, Volume: 111, Issue:2-3

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline

1981
Liquid-chromatographic analysis for common tricyclic antidepressant drugs and their metabolites in serum or plasma with the technicon "FAST-LC" system.
    Clinical chemistry, 1981, Volume: 27, Issue:6

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Autoanalysis; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Protriptyline

1981
Dual ultraviolet wavelength high-performance liquid chromatographic method for the forensic or clinical analysis of seventeen antidepressants and some selected metabolites.
    Journal of chromatography, 1993, Nov-24, Volume: 621, Issue:2

    Topics: Amitriptyline; Antidepressive Agents; Chromatography, High Pressure Liquid; Dothiepin; Doxepin; Forensic Medicine; Humans; Microchemistry; Nortriptyline; Postmortem Changes; Quality Control

1993
Spectrophotometric determination of some antidepressant drugs using 3-methylbenzothiazolin-2-one hydrazone.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 1999, Volume: 9, Issue:2

    Topics: Amitriptyline; Antidepressive Agents; Benzothiazoles; Chlorides; Doxepin; Excipients; Ferric Compounds; Hydrazones; Hydrochloric Acid; Nortriptyline; Spectrophotometry; Thiazoles; Time Factors

1999
Stereoselective measurement of E- and Z-doxepin and its N-desmethyl and hydroxylated metabolites by gas chromatography-mass spectrometry.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Dec-24, Volume: 736, Issue:1-2

    Topics: Antidepressive Agents, Tricyclic; Calibration; Doxepin; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; Hydroxylation; Microsomes, Liver; Nortriptyline; Sensitivity and Specificity; Stereoisomerism

1999
Tricyclic antidepressants as long-acting local anesthetics.
    Pain, 2003, Volume: 103, Issue:1-2

    Topics: Amines; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Cell Line; Dose-Response Relationship, Drug; Doxepin; Electric Impedance; Embryo, Mammalian; Humans; Kidney; Male; Membrane Potentials; Motor Activity; Neurologic Examination; Nortriptyline; Pain; Pain Measurement; Patch-Clamp Techniques; Proprioception; Rats; Rats, Sprague-Dawley; Recovery of Function; Sciatic Nerve; Substance-Related Disorders; Time Factors; Transfection

2003
Excess fatality from desipramine in children and adolescents.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2006, Volume: 45, Issue:1

    Topics: Adolescent; Amitriptyline; Child; Desipramine; Doxepin; Humans; Imipramine; Incidence; Mortality; Nortriptyline; Prevalence; Substance-Related Disorders

2006
Suitability of 1-hexyl-3-methylimidazolium ionic liquids for the analysis of pharmaceutical formulations containing tricyclic antidepressants.
    Journal of chromatography. A, 2018, Jul-20, Volume: 1559

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Borates; Chromatography, Reverse-Phase; Doxepin; Drug Compounding; Imidazoles; Ionic Liquids; Limit of Detection; Nortriptyline; Spectrophotometry, Ultraviolet

2018
Tricyclic antidepressants inhibit Candida albicans growth and biofilm formation.
    International journal of antimicrobial agents, 2018, Volume: 52, Issue:4

    Topics: Amphotericin B; Antidepressive Agents, Tricyclic; Antifungal Agents; Biofilms; Candida; Candida albicans; Candida glabrata; Doxepin; Drug Repositioning; Drug Synergism; Fungal Proteins; Gene Expression Regulation, Fungal; Humans; Hyphae; Imipramine; Inactivation, Metabolic; Microsomes, Liver; Nortriptyline; Plankton

2018
Analysis of smoking behavior on the pharmacokinetics of antidepressants and antipsychotics: evidence for the role of alternative pathways apart from CYP1A2.
    International clinical psychopharmacology, 2019, Volume: 34, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Clozapine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Desvenlafaxine Succinate; Doxepin; Drug Monitoring; Female; Glucuronosyltransferase; Humans; Male; Middle Aged; Mirtazapine; Nortriptyline; Paliperidone Palmitate; Quetiapine Fumarate; Retrospective Studies; Risperidone; Smoking; Venlafaxine Hydrochloride

2019
Nortriptyline serum concentration as a predictor for cardiac risk in amitriptyline-treated patients.
    European journal of clinical pharmacology, 2020, Volume: 76, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Tricyclic; Atrioventricular Block; Bundle-Branch Block; Doxepin; Electrocardiography; Female; Heart; Heart Function Tests; Humans; Male; Middle Aged; Nortriptyline; Retrospective Studies; Risk Factors

2020
Supramolecular microextraction combined with paper spray ionization mass spectrometry for sensitive determination of tricyclic antidepressants in urine.
    Analytica chimica acta, 2020, Apr-15, Volume: 1106

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Doxepin; Humans; Imipramine; Liquid Phase Microextraction; Macromolecular Substances; Mass Spectrometry; Molecular Structure; Nortriptyline; Paper

2020