doxepin and mirtazapine

doxepin has been researched along with mirtazapine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.76)18.2507
2000's11 (52.38)29.6817
2010's9 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ahlfors, U; Jääskeläinen, J; Järvi, R; Marttila, M; Miettinen, E; Romanov, M; Sorri, P; Zivkov, M1
Croft, HA; Labbate, LA; Oleshansky, MA1
Grauer, MT; Holsboer, F; Uhr, M1
Bateman, DN; Chick, J; Good, AM; Kelly, CA; Masterton, G1
Bajbouj, M; Danker-Hopfe, H; Gallinat, J; Hellen, F; Lang, UE; Lisanby, SH; Neu, P; Vesper, J1
Wichniak, A; Wierzbicka, A1
Clark, MS; Jamieson, B; Smith, PO1
Funaki, Y; Hiraoka, K; Ito, C; Iwata, R; Matsuoka, H; Sato, H; Shibuya, K; Tashiro, M; Yanai, K1
Reich, A; Szepietowski, JC1
Fay, B; Gründer, G; Haen, E; Hiemke, C; Paulzen, M; Schoretsanitis, G; Unholzer, S1
Deckert, J; Hommers, LG; Menke, A; Samanski, L; Scherf-Clavel, M; Unterecker, S1

Reviews

4 review(s) available for doxepin and mirtazapine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antidepressant-related erectile dysfunction: management via avoidance, switching antidepressants, antidotes, and adaptation.
    The Journal of clinical psychiatry, 2003, Volume: 64 Suppl 10

    Topics: Antidepressive Agents; Bupropion; Controlled Clinical Trials as Topic; Depressive Disorder; Doxepin; Drug Tolerance; Erectile Dysfunction; Humans; Male; Mianserin; Mirtazapine; Moclobemide; Orgasm; Piperazines; Remission, Spontaneous; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Triazoles

2003
[The effects of antidepressants on sleep in depressed patients with particular reference to trazodone in comparison to agomelatine, amitriptyline, doxepin, mianserine and mirtazapine].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2011, Volume: 31, Issue:181

    Topics: Amitriptyline; Antidepressive Agents; Depression; Doxepin; Humans; Mianserin; Mirtazapine; Sleep; Sleep Initiation and Maintenance Disorders; Sleep, REM; Trazodone

2011
Itch in Psoriasis Management.
    Current problems in dermatology, 2016, Volume: 50

    Topics: Adaptation, Psychological; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Doxepin; Histamine Antagonists; Humans; Mianserin; Mirtazapine; Paroxetine; Pruritus; Psoriasis; Social Support; Thalidomide; Ultraviolet Therapy

2016

Trials

3 trial(s) available for doxepin and mirtazapine

ArticleYear
A double-blind study comparing the efficacy and tolerability of mirtazapine and doxepin in patients with major depression.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1995, Volume: 5, Issue:4

    Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Doxepin; Female; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Psychiatric Status Rating Scales

1995
Motor cortex excitability after vagus nerve stimulation in major depression.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Adult; Benzodiazepines; Citalopram; Clomipramine; Clozapine; Depressive Disorder; Doxepin; Drug Therapy, Combination; Electric Stimulation; Female; Humans; Lamotrigine; Lithium Carbonate; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Motor Cortex; Neural Conduction; Neural Inhibition; Olanzapine; Paroxetine; Psychiatric Status Rating Scales; Reboxetine; Tranylcypromine; Triazines; Vagus Nerve; Valproic Acid

2007
Histamine H₁ receptor occupancy by the new-generation antidepressants fluvoxamine and mirtazapine: a positron emission tomography study in healthy volunteers.
    Psychopharmacology, 2013, Volume: 230, Issue:2

    Topics: Administration, Oral; Adult; Antidepressive Agents; Area Under Curve; Brain; Chromatography, Liquid; Double-Blind Method; Doxepin; Fluvoxamine; Histamine H1 Antagonists; Humans; Male; Mianserin; Mirtazapine; Positron-Emission Tomography; Receptors, Histamine H1; Sleep Stages; Tandem Mass Spectrometry; Young Adult

2013

Other Studies

14 other study(ies) available for doxepin and mirtazapine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Differential enhancement of antidepressant penetration into the brain in mice with abcb1ab (mdr1ab) P-glycoprotein gene disruption.
    Biological psychiatry, 2003, Oct-15, Volume: 54, Issue:8

    Topics: Animals; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Chromatography, High Pressure Liquid; Cyclohexanols; Doxepin; Drug Resistance, Multiple; Gene Expression; Injections, Subcutaneous; Kidney; Liver; Male; Mianserin; Mice; Mice, Knockout; Mirtazapine; Paroxetine; Point Mutation; Spleen; Venlafaxine Hydrochloride

2003
Are selective serotonin re-uptake inhibitors associated with an increased risk of self-harm by antidepressant overdose?
    European journal of clinical pharmacology, 2004, Volume: 60, Issue:3

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Doxepin; Drug Overdose; Drug Prescriptions; Emergency Service, Hospital; Female; Fluoxetine; Humans; Imipramine; Information Services; Male; Mianserin; Mirtazapine; Paroxetine; Patient Admission; Patient Readmission; Poison Control Centers; Retrospective Studies; Risk Assessment; Scotland; Selective Serotonin Reuptake Inhibitors; Self-Injurious Behavior; Sertraline; Trazodone; Venlafaxine Hydrochloride

2004
FPIN's clinical inquiries: Antidepressants for the treatment of insomnia in patients with depression.
    American family physician, 2011, Nov-01, Volume: 84, Issue:9

    Topics: Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Dose-Response Relationship, Drug; Doxepin; Evidence-Based Medicine; Humans; Mianserin; Mirtazapine; Practice Guidelines as Topic; Sleep Initiation and Maintenance Disorders; Trazodone; Trimipramine

2011
Antidepressant polypharmacy and the potential of pharmacokinetic interactions: Doxepin but not mirtazapine causes clinically relevant changes in venlafaxine metabolism.
    Journal of affective disorders, 2018, Volume: 227

    Topics: Adult; Antidepressive Agents, Second-Generation; Cyclohexanols; Databases, Factual; Desvenlafaxine Succinate; Doxepin; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Polypharmacy; Venlafaxine Hydrochloride

2018
Analysis of smoking behavior on the pharmacokinetics of antidepressants and antipsychotics: evidence for the role of alternative pathways apart from CYP1A2.
    International clinical psychopharmacology, 2019, Volume: 34, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Clozapine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Desvenlafaxine Succinate; Doxepin; Drug Monitoring; Female; Glucuronosyltransferase; Humans; Male; Middle Aged; Mirtazapine; Nortriptyline; Paliperidone Palmitate; Quetiapine Fumarate; Retrospective Studies; Risperidone; Smoking; Venlafaxine Hydrochloride

2019