doxepin and chlorpheniramine
doxepin has been researched along with chlorpheniramine in 20 studies
Research
Studies (20)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (30.00) | 18.7374 |
1990's | 3 (15.00) | 18.2507 |
2000's | 6 (30.00) | 29.6817 |
2010's | 4 (20.00) | 24.3611 |
2020's | 1 (5.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
Andrews, PR; Craik, DJ; Martin, JL | 1 |
Chiang, GH; Unger, SH | 1 |
Strassburg, CP; Tukey, RH | 1 |
Topliss, JG; Yoshida, F | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Ahman, M; Holmén, AG; Wan, H | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Hatazawa, J; Ido, T; Ishiwata, K; Itoh, M; Iwata, R; Meguro, K; Takahashi, T; Watanabe, T; Yanai, K; Yokoyama, H | 1 |
Barr, RJ; Drayton, G; Goldsobel, AB; Indianer, L; Katz, RM; Peter, JB; Rachelefsky, GS; Rohr, AS; Siegel, SC; Spector, SL | 1 |
Lassen, JB | 1 |
Sullivan, TJ | 1 |
Ido, T; Ito, K; Itoh, M; Iwata, R; Ryu, JH; Sawai, Y; Watanabe, T; Yanai, K | 1 |
Itoh, M; Okamura, N; Watanabe, T; Yanai, K | 1 |
Baek, SY; Kim, HI; Kim, JH; Kim, YK; Shin, DW; Woo, IS | 1 |
Reviews
2 review(s) available for doxepin and chlorpheniramine
Article | Year |
---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Trials
2 trial(s) available for doxepin and chlorpheniramine
Article | Year |
---|---|
Efficacy of doxepin in the treatment of chronic idiopathic urticaria.
Topics: Chlorpheniramine; Codeine; Doxepin; Histamine; Humans; Skin; Skin Tests; Urticaria | 1986 |
Pharmacologic modulation of the whealing response to histamine in human skin: identification of doxepin as a potent in vivo inhibitor.
Topics: Adult; Antidepressive Agents, Tricyclic; Chlorpheniramine; Dose-Response Relationship, Immunologic; Double-Blind Method; Doxepin; Histamine; Histamine H1 Antagonists; Humans; Placebos; Skin Tests | 1982 |
Other Studies
16 other study(ies) available for doxepin and chlorpheniramine
Article | Year |
---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Histamine H1 receptors in human brain visualized in vivo by [11C]doxepin and positron emission tomography.
Topics: Adult; Brain; Carbon Isotopes; Chlorpheniramine; Doxepin; Humans; Injections, Intravenous; Male; Pyrilamine; Receptors, Histamine H1; Tomography, Emission-Computed | 1992 |
The effect of p-chloroamphetamine on motility in rats after inhibition of monoamine synthesis, storage, uptake and receptor interaction.
Topics: Amitriptyline; Amphetamine; Animals; Biogenic Amines; Catecholamines; Chlorine; Chlorpheniramine; Chlorpromazine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Doxepin; Female; Haloperidol; Imipramine; Methyltyrosines; Motor Activity; Rats; Receptors, Cholinergic; Serotonin Antagonists; Spiro Compounds; Time Factors | 1974 |
Histamine H1 receptor occupancy in human brains after single oral doses of histamine H1 antagonists measured by positron emission tomography.
Topics: Administration, Oral; Adult; Animals; Brain; Carbon Radioisotopes; Chlorpheniramine; Doxepin; Guinea Pigs; Histamine H1 Antagonists; Humans; Male; Receptors, Histamine H1; Terfenadine; Tomography, Emission-Computed | 1995 |
[Functional neuropharmacology in the human brain using positron emission tomography: PET imaging of impaired cognitive performance induced by sedative antihistamines].
Topics: Animals; Brain; Chlorpheniramine; Cognition; Doxepin; Histamine Antagonists; Histamine H1 Antagonists; Humans; Male; Receptors, Histamine H1; Sleep Stages; Tomography, Emission-Computed | 1998 |
Development and validation of a simultaneous analytical method for non-steroidal therapeutic compounds in cosmetics using liquid chromatography-tandem mass spectrometry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bufexamac; Chlorpheniramine; Chromatography, High Pressure Liquid; Clotrimazole; Cosmetics; Doxepin; Fusidic Acid; Ketotifen; ortho-Aminobenzoates; Phthalazines; Tacrolimus; Tandem Mass Spectrometry | 2021 |