doxazosin and losartan

doxazosin has been researched along with losartan in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.76)18.2507
2000's10 (58.82)29.6817
2010's4 (23.53)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Funakoshi, J; Kakumoto, M; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Abeta, H; Asagami, T; Furukawa, L; Hino, T; Ishii, T; Kushiro, T; Otsuka, Y; Saito, F; Takahashi, A; Tomiyama, H1
Cachofeiro, V; Lahera, V; Maeso, R; Navarro-Cid, J; Rodrigo, E; Ruilope, LM1
Khan, MA; Mikhailidis, DP; Morgan, RJ1
Gurevich, MA1
Diener, HC1
Asai, T; Fujita, H; Kanmatsuse, K; Kushiro, T1
Barderas, MG; Duran, MC; Egido, J; Gallego-Delgado, J; Lazaro, A; Osende, JI; Vivanco, F1
Brady, HR; Connolly, SB; Doran, P; Egido, J; Gallego-Delgado, J; Kieran, NE; Lázaro, A; Osende, J; Sadlier, D; Sugrue, DD1
Gandhi, HP; Giridhar, R; Naik, PP; Yadav, MR1
Dobrokhod, AS; Kushnir, SM; Radchenko, GD; Sirenko, YM; Torbas, OO1
Brown, MJ; Caulfield, M; Cruickshank, JK; Ford, I; MacDonald, TM; Mackenzie, IS; McCann, GP; McInnes, G; Morant, S; Padmanabhan, S; Salsbury, J; Sever, P; Webb, DJ; Williams, B1

Reviews

2 review(s) available for doxazosin and losartan

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Policy of antihypertensive therapy in arterial hypertension in the elderly. II].
    Klinicheskaia meditsina, 2002, Volume: 80, Issue:9

    Topics: Acrylates; Adrenergic alpha-Antagonists; Age Factors; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Doxazosin; Female; Humans; Hypertension; Imidazoles; Losartan; Male; Perindopril; Risk Factors; Sex Factors; Sodium Chloride Symporter Inhibitors; Thiophenes

2002

Trials

2 trial(s) available for doxazosin and losartan

ArticleYear
Comparative effectiveness of a fixed-dose combination of losartan + HCTZ versus bisoprolol + HCTZ in patients with moderate-to-severe hypertension: results of the 6-month ELIZA trial.
    Vascular health and risk management, 2013, Volume: 9

    Topics: Adrenergic beta-1 Receptor Antagonists; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Bisoprolol; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chi-Square Distribution; Diuretics; Doxazosin; Drug Combinations; Drug Therapy, Combination; Electrocardiography; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Pulse Wave Analysis; Severity of Illness Index; Time Factors; Treatment Outcome; Ukraine; Vascular Stiffness

2013
Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double-Blind Randomized Controlled Trial.
    Journal of the American Heart Association, 2017, Nov-18, Volume: 6, Issue:11

    Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Doxazosin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Treatment Outcome; Young Adult

2017

Other Studies

13 other study(ies) available for doxazosin and losartan

ArticleYear
Interaction of digoxin with antihypertensive drugs via MDR1.
    Life sciences, 2002, Feb-15, Volume: 70, Issue:13

    Topics: Animals; Antihypertensive Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Digoxin; Drug Interactions; Humans; Time Factors

2002
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Kinins contribute to the improvement of insulin sensitivity during treatment with angiotensin converting enzyme inhibitor.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:4

    Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Glucose; Blood Pressure; Body Weight; Bradykinin; Doxazosin; Enalapril; Glucose Clamp Technique; Hypertension; Imidazoles; Insulin; Kinins; Losartan; Male; Potassium; Rats; Rats, Inbred SHR; Sodium; Tetrazoles

1994
Differential effects of losartan and doxazosin on vascular function in senescent spontaneously hypertensive rats.
    American journal of hypertension, 1999, Volume: 12, Issue:11 Pt 1

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Aging; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Doxazosin; Endothelium, Vascular; Hypertension; Losartan; Male; Nitrates; Nitroprusside; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasodilation; Vasodilator Agents

1999
The choice of antihypertensive drugs in patients with erectile dysfunction.
    Current medical research and opinion, 2002, Volume: 18, Issue:2

    Topics: Aged; Antihypertensive Agents; Diabetes Complications; Doxazosin; Erectile Dysfunction; Humans; Hypertension; Insulin Resistance; Losartan; Male; Middle Aged

2002
[Primary prevention of stroke. What helps--what does not help? The guidelines of the German Society of Neurology briefly summarized].
    MMW Fortschritte der Medizin, 2003, Volume: 145 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Alcohol Drinking; Anticholesteremic Agents; Anticoagulants; Antihypertensive Agents; Arrhythmias, Cardiac; Aspirin; Atenolol; Atrial Fibrillation; Carotid Artery, Internal; Carotid Stenosis; Chlorthalidone; Clinical Trials as Topic; Diabetes Complications; Diuretics; Doxazosin; Female; Fibrinolytic Agents; Hormone Replacement Therapy; Humans; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Life Style; Losartan; Male; Neurology; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Pravastatin; Primary Prevention; Risk Factors; Simvastatin; Smoking; Societies, Medical; Stroke

2003
Different effects on inhibition of cardiac hypertrophy in spontaneously hypertensive rats by monotherapy and combination therapy of adrenergic receptor antagonists and/or the angiotensin II type 1 receptor blocker under comparable blood pressure reduction
    Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atenolol; Blood Pressure; Cardiomegaly; Doxazosin; Drug Therapy, Combination; Echocardiography; Heart Rate; Hypertension; Losartan; Male; Natriuretic Peptide, Brain; Rats; Rats, Inbred SHR; RNA, Messenger

2005
Comparison of the protein profile of established and regressed hypertension-induced left ventricular hypertrophy.
    Journal of proteome research, 2006, Volume: 5, Issue:2

    Topics: Amino Acid Sequence; Animals; Antihypertensive Agents; Blood Pressure; Doxazosin; Electrophoresis, Gel, Two-Dimensional; Hypertrophy, Left Ventricular; Losartan; Molecular Sequence Data; Myocardium; Proteomics; Quinapril; Rats; Rats, Inbred WKY; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrahydroisoquinolines

2006
Transcriptome of hypertension-induced left ventricular hypertrophy and its regression by antihypertensive therapies.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:5

    Topics: Animals; Antihypertensive Agents; Doxazosin; Drug Therapy, Combination; Gene Expression; Gene Expression Profiling; Hypertension; Hypertrophy, Left Ventricular; Losartan; Oligonucleotide Array Sequence Analysis; Quinapril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrahydroisoquinolines

2009
Revelation on the potency of α(1) -blockers - parallel blockade of angiotensin II receptor: a new finding.
    Pharmaceutical biology, 2012, Volume: 50, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Dose-Response Relationship, Drug; Doxazosin; Imidazoles; In Vitro Techniques; Losartan; Male; Molecular Structure; Prazosin; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, alpha-1; Structure-Activity Relationship; Tetrazoles; Valine; Valsartan; Vasodilation; Vasodilator Agents

2012