doxazosin and enalapril

doxazosin has been researched along with enalapril in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.56)18.7374
1990's21 (58.33)18.2507
2000's8 (22.22)29.6817
2010's5 (13.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Funakoshi, J; Kakumoto, M; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Johnston, H; Marwood, JF; Monaghan, JC; Okoro, EO; Stokes, GS1
Branzi, A; Galiè, N; Limonetti, P; Magnani, B; Passarelli, P1
Brown, MJ; Dickerson, JE2
Donnelly, R; Elliott, HL; Howie, CA; Reid, JL; Sumner, DJ1
Wessels, F1
Donnelly, R; Elliott, HL; Meredith, PA; Reid, JL1
Marwood, J; Stokes, G; Tierney, G1
Lee, PS; Sharma, SK; Taylor, SH1
Berg, KJ; Blystad, L; Fauchald, P; Hartmann, A; Holdaas, H; Langberg, H1
Boutagy, J; Johnston, HJ; Marwood, JF; Monaghan, JC; Okoro, EO; Stokes, GS1
Abeta, H; Asagami, T; Furukawa, L; Hino, T; Ishii, T; Kushiro, T; Otsuka, Y; Saito, F; Takahashi, A; Tomiyama, H1
Alcázar de la Osa, JM; Fernández Pinilla, C; Luque Otero, M; Martell Claros, N; Rodicio Díaz, JL; Ruilope Urioste, LM1
Cutler, JA; Elmer, PJ; Flack, JM; Grandits, GA; Grimm, RH; McDonald, R; Neaton, JD; Prineas, RJ; Schoenberger, JA; Stamler, J1
Elmer, PJ; Flack, J; Grandits, A; Lewis, CE; McDonald, R1
Ansuini, R; Curnis, A; Gallucci, M; Malacco, E; Puddu, P; Pupita, F1
Andersson, PE; Lithell, H1
Elmer, PJ; Flack, JM; Grandits, GA; Grimm, RH; Lewis, CE; Liebson, PR; McDonald, RH; Prineas, RJ; Svendsen, K; Yunis, C1
Chesson, R; Menefee, SA; Wall, LL1
Iversen, BM; Kvam, FI; Ofstad, J1
Alsina, J; Grinyó, JM; Hueso, M; Martínez-Castelao, A; Rejas, J; Sanz, V1
Ebbs, D1
Alsina, J; Grinyó, JM; Hueso, M; Martínez-Castelao, A; Rejas, J; Sanz, V; Sarrias, J1
Ambrosioni, E1
Bainbridge, AD; Elliott, HL; Meredith, PA1
Davenport, AP; Dhaun, N; Ferro, CJ; Goddard, J; Haynes, WG; Webb, DJ1
Eder, DN; Grote, L; Hedner, J; Radlinski, J; Zou, D1
Alvarez-Ude, F; Fernández-Reyes, MJ; Heras, M; Pardo, J; Saiz, A; Sánchez, R1
Caça, I; Cınar, Y; Mehmet Türkcü, F; Sahin, A; Yıldırım, A; Yüksel, H1

Reviews

1 review(s) available for doxazosin and enalapril

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

24 trial(s) available for doxazosin and enalapril

ArticleYear
Increase in serum total angiotensin-converting enzyme activity with enalapril therapy in humans: a controlled trial.
    Clinical and experimental pharmacology & physiology, 1992, Volume: 19, Issue:5

    Topics: Double-Blind Method; Doxazosin; Drug Administration Schedule; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Prazosin; Renin-Angiotensin System

1992
[Comparative effects of doxazosin and enalapril in patients with arterial hypertension and exercise-induced acute myocardial ischemia].
    Cardiologia (Rome, Italy), 1991, Volume: 36, Issue:10

    Topics: Adrenergic alpha-Antagonists; Aged; Antihypertensive Agents; Coronary Disease; Doxazosin; Enalapril; Exercise Test; Female; Humans; Hypertension; Male; Middle Aged; Prazosin; Vasodilator Agents

1991
Synergism between alpha 1-blockade and angiotensin converting enzyme inhibition in essential hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:6

    Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Double-Blind Method; Doxazosin; Drug Synergism; Drug Therapy, Combination; Enalapril; Humans; Hypertension; Prazosin

1991
Vascular pressor responses in treated and untreated essential hypertension.
    Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:2

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Doxazosin; Enalapril; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Peptidyl-Dipeptidase A; Phenylephrine; Prazosin; Reflex; Regional Blood Flow; Renin

1990
Double-blind comparison of doxazosin and enalapril in patients with mild or moderate essential hypertension.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 2

    Topics: Antihypertensive Agents; Coronary Disease; Double-Blind Method; Doxazosin; Enalapril; Family Practice; Female; Germany, West; Humans; Hypertension; Lipids; Male; Middle Aged; Prazosin; Risk Factors

1991
Dose-response clarification in early drug development.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:6

    Topics: Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Doxazosin; Enalapril; Humans; Hypertension; Nifedipine; Prazosin

1991
A comparison of doxazosin and enalapril in the treatment of mild and moderate essential hypertension.
    American heart journal, 1988, Volume: 116, Issue:6 Pt 2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Doxazosin; Enalapril; Female; Humans; Hypertension; Lipids; Male; Middle Aged; Prazosin

1988
Alpha-blockade and calcium antagonism: an effective and well-tolerated combination for the treatment of resistant hypertension.
    Journal of hypertension, 1995, Volume: 13, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method; Doxazosin; Drug Synergism; Drug Therapy, Combination; Enalapril; Female; Humans; Hypertension; Male; Middle Aged

1995
Contrasting effects of angiotensin converting inhibitor and alpha-1-antagonist on albuminuria in insulin-dependent diabetes mellitus patients with nephropathy.
    Journal of internal medicine, 1995, Volume: 237, Issue:1

    Topics: Adult; Albuminuria; Creatinine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Doxazosin; Enalapril; Female; Humans; Kidney Tubules; Male; Middle Aged; Renal Circulation

1995
Comparative and combined efficacy of doxazosin and enalapril in hypertensive patients.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1994, Volume: 16, Issue:6

    Topics: Acetylcholinesterase; Adult; Aged; Blood Pressure; Cross-Over Studies; Double-Blind Method; Doxazosin; Drug Synergism; Enalapril; Female; Humans; Hypertension; Lipids; Male; Middle Aged; Renin

1994
Combined effect of a low fat diet and doxazosin on blood pressure control and blood lipids. Hunter Hypertension Research Group.
    Journal of human hypertension, 1994, Volume: 8, Issue:12

    Topics: Adult; Aged; Blood Glucose; Blood Pressure Monitoring, Ambulatory; Diet, Fat-Restricted; Doxazosin; Enalapril; Female; Humans; Hypercholesterolemia; Hypertension; Insulin; Lipids; Male; Middle Aged

1994
[Treatment of essential arterial hypertension with hypercholesterolemia. Effects of an alpha-adrenergic blocker and an inhibitor of the angiotensin converting enzyme].
    Medicina clinica, 1993, Jun-26, Volume: 101, Issue:5

    Topics: Adult; Aged; Doxazosin; Enalapril; Female; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged

1993
Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group.
    JAMA, 1993, Aug-11, Volume: 270, Issue:6

    Topics: Acebutolol; Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Diastole; Double-Blind Method; Doxazosin; Echocardiography; Electrocardiography; Enalapril; Exercise; Female; Follow-Up Studies; Health Behavior; Humans; Hypertension; Long-Term Care; Male; Middle Aged; Treatment Outcome

1993
Efficacy and tolerance of antihypertensive treatment in men and women with stage 1 diastolic hypertension. Results of the Treatment of Mild Hypertension Study.
    Archives of internal medicine, 1996, Feb-26, Volume: 156, Issue:4

    Topics: Acebutolol; Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Doxazosin; Enalapril; Female; Humans; Hygiene; Hypertension; Life Style; Male; Middle Aged; Nutritional Physiological Phenomena; Patient Education as Topic; Severity of Illness Index; Treatment Outcome

1996
[Evaluation of the efficacy and tolerance of doxazosin vs. enalapril inaged patients with light to moderate arterial hypertension].
    La Clinica terapeutica, 1995, Volume: 146, Issue:12

    Topics: Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Body Weight; Dose-Response Relationship, Drug; Doxazosin; Echocardiography; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Sex Factors

1995
Metabolic effects of doxazosin and enalapril in hypertriglyceridemic, hypertensive men. Relationship to changes in skeletal muscle blood flow.
    American journal of hypertension, 1996, Volume: 9, Issue:4 Pt 1

    Topics: Adult; Aged; Antihypertensive Agents; Body Mass Index; Double-Blind Method; Doxazosin; Enalapril; Female; Glucose; Hemodynamics; Humans; Hypertension; Hypertriglyceridemia; Insulin Resistance; Leg; Male; Middle Aged

1996
Long-term effects on sexual function of five antihypertensive drugs and nutritional hygienic treatment in hypertensive men and women. Treatment of Mild Hypertension Study (TOMHS)
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:1 Pt 1

    Topics: Acebutolol; Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Double-Blind Method; Doxazosin; Enalapril; Female; Humans; Hypertension; Libido; Male; Middle Aged; Orgasm; Penile Erection; Sexual Dysfunction, Physiological

1997
Treatment of hypertension after renal transplantation: long-term efficacy of verapamil, enalapril, and doxazosin.
    Kidney international. Supplement, 1998, Volume: 68

    Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Doxazosin; Enalapril; Female; Follow-Up Studies; Graft Survival; Humans; Hypercholesterolemia; Hypertension, Renal; Kidney Failure, Chronic; Kidney Transplantation; Longitudinal Studies; Male; Middle Aged; Postoperative Complications; Verapamil

1998
A comparison of selected antihypertensives and the use of conventional vs ambulatory blood pressure in the detection and treatment of hypertension.
    Cardiology, 2001, Volume: 96 Suppl 1

    Topics: Adult; Aged; Amlodipine; Analysis of Variance; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Blood Pressure Determination; Blood Pressure Monitoring, Ambulatory; Diastole; Double-Blind Method; Doxazosin; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Systole; Treatment Outcome

2001
Double-blind, crossover, comparative study of doxazosin and enalapril in the treatment of hypertension in renal transplant patients under cyclosporine immunosuppression.
    Transplantation proceedings, 2002, Volume: 34, Issue:1

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood Pressure; Creatinine; Cross-Over Studies; Cyclosporine; Double-Blind Method; Doxazosin; Enalapril; Female; Glomerular Filtration Rate; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Lipids; Male; Postoperative Complications; Proteinuria; Uric Acid

2002
[Management of hypertensive patients with left ventricular hypertrophy].
    Presse medicale (Paris, France : 1983), 2002, Volume: 31 Spec No 2

    Topics: Adrenergic alpha-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Doxazosin; Drug Therapy, Combination; Echocardiography; Electrocardiography; Enalapril; Humans; Hypertension; Hypertrophy, Left Ventricular; Indapamide; Placebos; Prazosin; Prognosis; Prospective Studies; Risk Factors; Time Factors

2002
A clinical pharmacological assessment of doxazosin and enalapril in combination.
    British journal of clinical pharmacology, 1993, Volume: 36, Issue:6

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Doxazosin; Drug Combinations; Drug Interactions; Enalapril; Glomerular Filtration Rate; Heart Rate; Humans; Male; Pressoreceptors; Renal Plasma Flow, Effective

1993
Haemodynamic and renal effects of endothelin receptor antagonism in patients with chronic kidney disease.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:11

    Topics: Adult; Blood Pressure; Cross-Over Studies; Double-Blind Method; Doxazosin; Enalapril; Endothelin Receptor Antagonists; Furosemide; Hemodynamics; Humans; Kidney Failure, Chronic; Male; Metoprolol; Middle Aged; Peptides, Cyclic; Prospective Studies

2007
A double-blind, crossover study of Doxazosin and Enalapril on peripheral vascular tone and nocturnal blood pressure in sleep apnea patients.
    Sleep medicine, 2010, Volume: 11, Issue:3

    Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Double-Blind Method; Doxazosin; Enalapril; Heart Rate; Humans; Hypertension; Male; Middle Aged; Polysomnography; Sleep; Sleep Apnea, Obstructive; Vasoconstriction

2010

Other Studies

11 other study(ies) available for doxazosin and enalapril

ArticleYear
Interaction of digoxin with antihypertensive drugs via MDR1.
    Life sciences, 2002, Feb-15, Volume: 70, Issue:13

    Topics: Animals; Antihypertensive Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Digoxin; Drug Interactions; Humans; Time Factors

2002
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
An in vitro study of interactions between doxazosin and enalaprilat at vascular alpha 1-adrenoceptors.
    Clinical and experimental pharmacology & physiology, 1989, Volume: 16, Issue:4

    Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessels; Doxazosin; Drug Interactions; Enalapril; Enalaprilat; In Vitro Techniques; Male; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Renin-Angiotensin System

1989
Kinins contribute to the improvement of insulin sensitivity during treatment with angiotensin converting enzyme inhibitor.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:4

    Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Glucose; Blood Pressure; Body Weight; Bradykinin; Doxazosin; Enalapril; Glucose Clamp Technique; Hypertension; Imidazoles; Insulin; Kinins; Losartan; Male; Potassium; Rats; Rats, Inbred SHR; Sodium; Tetrazoles

1994
Stress urinary incontinence due to prescription medications: alpha-blockers and angiotensin converting enzyme inhibitors.
    Obstetrics and gynecology, 1998, Volume: 91, Issue:5 Pt 2

    Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cough; Doxazosin; Enalapril; Female; Humans; Middle Aged; Urinary Incontinence, Stress

1998
Effects of antihypertensive drugs on autoregulation of RBF and glomerular capillary pressure in SHR.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Capillaries; Doxazosin; Enalapril; Homeostasis; Hypertension; Kidney; Kidney Glomerulus; Male; Nifedipine; Rats; Rats, Inbred SHR; Regional Blood Flow; Renal Circulation; Verapamil

1998
[Rapidly progressive renal failure as the onset of an IgA nephropathy in an elderly patient].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2011, Volume: 31, Issue:2

    Topics: Acute Kidney Injury; Adenocarcinoma; Aged; Biphenyl Compounds; Disease Progression; Diuretics; Doxazosin; Drug Therapy, Combination; Enalapril; Furosemide; Glomerulonephritis, IGA; Humans; Irbesartan; Male; Methylprednisolone; Nocturia; Prednisone; Prostatic Neoplasms; Remission Induction; Renal Dialysis; Tetrazoles

2011
Diagnosis of malignant hypertension with ocular examination: a child case.
    Seminars in ophthalmology, 2014, Volume: 29, Issue:1

    Topics: Antihypertensive Agents; Blood Pressure; Child; Doxazosin; Drug Therapy, Combination; Enalapril; Female; Fluorescein Angiography; Humans; Hypertension, Malignant; Intraocular Pressure; Nifedipine; Papilledema; Retinal Hemorrhage; Tomography, Optical Coherence; Tonometry, Ocular; Vasodilator Agents; Vesico-Ureteral Reflux; Visual Acuity

2014