doxapram and naloxone

doxapram has been researched along with naloxone in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199017 (80.95)18.7374
1990's1 (4.76)18.2507
2000's1 (4.76)29.6817
2010's2 (9.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Grote, B1
Khanna, VK; Pleuvry, BJ1
Dundee, JW; Gawley, TH; Gupta, PK; Jones, CJ1
Dundee, JW; Gawley, TH; Jones, CJ1
Beesley, JR; Bowden, G; Hardy, RH; Reynolds, TD1
Locke, RG; Salvia, JV1
Hatch, RC; Jernigan, AD1
Otsuka, H1
Dowell, RT; Eldridge, FL; Paydarfar, D; Scott, SC1
Booth, NH; Brown, J; Clark, JD; Hatch, RC; Jernigan, AD; Lipham, IB; Wilson, RC1
Dundee, JW; Gupta, PK2
Dundee, JW; Gupta, PK; Jones, CJ; Walker, FS1
Dundee, JW; Gupta, PK; Jones, CJ1
Gairola, RL; Gupta, PK; Pandley, K1
Roy, RC; Stullken, EH1
Decker, WJ; Gay, GR; Inaba, DS; Rappolt, RT1
Gay, GR; Inaba, D; Rappolt, RT1
Aarts, L; Algera, MH; Dahan, A; Kamp, J; Niesters, M; Olofsen, E; van der Schrier, R; van Velzen, M1

Reviews

4 review(s) available for doxapram and naloxone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacologic manipulation of the respiratory control center in the infant.
    The Journal of the American Osteopathic Association, 1990, Volume: 90, Issue:7

    Topics: Almitrine; Doxapram; Drug Therapy; Humans; Infant; Infant, Newborn; Naloxone; Progesterone; Prostaglandins; Respiratory Center; Respiratory Insufficiency; Respiratory Muscles; Theophylline

1990
[Are respiratory stimulants necessary? Yes].
    Kokyu to junkan. Respiration & circulation, 1987, Volume: 35, Issue:4

    Topics: Almitrine; Central Nervous System Stimulants; Doxapram; Humans; Naloxone; Piperazines; Progesterone; Respiration, Artificial; Respiratory Insufficiency; Theophylline

1987
Opioid-induced respiratory depression in humans: a review of pharmacokinetic-pharmacodynamic modelling of reversal.
    British journal of anaesthesia, 2019, Volume: 122, Issue:6

    Topics: Analgesics, Opioid; Carotid Body; Doxapram; Drug Design; Humans; Models, Biological; Naloxone; Narcotic Antagonists; Respiratory Insufficiency; Triazines

2019

Trials

4 trial(s) available for doxapram and naloxone

ArticleYear
Role of doxapram in reducing pulmonary complications after major surgery.
    British medical journal, 1976, Jan-17, Volume: 1, Issue:6002

    Topics: Adolescent; Adult; Clinical Trials as Topic; Cough; Doxapram; Female; Humans; Lung Diseases; Male; Middle Aged; Morphine; Naloxone; Oxygen; Postoperative Complications; Sputum

1976
Morphine combined with doxapram or naloxone. A study of post-operative pain relief.
    Anaesthesia, 1974, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Aged; Analgesia; Blood Pressure; Body Weight; Clinical Trials as Topic; Doxapram; Drug Interactions; Heart Rate; Humans; Middle Aged; Morphine; Naloxone; Pain; Postoperative Care; Respiration; Time Factors

1974
Opiate analgesia without respiratory depression: a study in postoperative patients.
    British journal of anaesthesia, 1973, Volume: 45, Issue:6

    Topics: Anesthesia, General; Doxapram; Humans; Morphine; Naloxone; Placebos; Postoperative Complications; Respiration

1973
Antagonists of morphine-induced respiratory depression. A study in postoperative patients.
    Anaesthesia, 1980, Volume: 35, Issue:1

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Doxapram; Humans; Levallorphan; Middle Aged; Morphine; Naloxone; Narcotic Antagonists; Pain, Postoperative; Random Allocation; Respiratory Insufficiency; Thiazoles; Time Factors

1980

Other Studies

13 other study(ies) available for doxapram and naloxone

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
[Analeptics].
    Der Anaesthesist, 1977, Volume: 26, Issue:4

    Topics: Central Nervous System Stimulants; Doxapram; Naloxone

1977
A study of naloxone and doxapram as agents for the reversal of neuroleptanalgesic respiratory depression in the conscious rabbit.
    British journal of anaesthesia, 1978, Volume: 50, Issue:9

    Topics: Animals; Carbon Dioxide; Depression, Chemical; Doxapram; Droperidol; Fentanyl; Hydrogen-Ion Concentration; Lethal Dose 50; Male; Naloxone; Neuroleptanalgesia; Rabbits; Respiration; Respiratory Function Tests; Time Factors

1978
Proceedings: The role of doxapram in the reduction of pulmonary complications following surgery.
    British journal of anaesthesia, 1975, Volume: 47, Issue:8

    Topics: Adolescent; Adult; Doxapram; Humans; Injections, Intravenous; Middle Aged; Morphine; Naloxone; Postoperative Complications; Respiratory Function Tests

1975
Intravenous diazepam narcosis in the treatment of injuries, with doxapram for recovery.
    Resuscitation, 1975, Volume: 4, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Child; Diazepam; Doxapram; Female; Fractures, Bone; Humans; Male; Manipulation, Orthopedic; Middle Aged; Naloxone; Respiratory Insufficiency; Wounds and Injuries

1975
Effect of intravenously-administered putative and potential antagonists of ethanol on sleep time in ethanol-narcotized mice.
    Life sciences, 1988, Volume: 42, Issue:1

    Topics: 4-Aminopyridine; Alcoholic Intoxication; Aminophylline; Aminopyridines; Amphetamine; Animals; Azides; Benzodiazepines; Dextroamphetamine; Doxapram; Ethanol; Male; Mice; Naloxone; Physostigmine; Propranolol; Sleep; Thyrotropin-Releasing Hormone; Yohimbine

1988
Role of endogenous adenosine in recurrent generalized seizures.
    Experimental neurology, 1989, Volume: 103, Issue:2

    Topics: Adenosine; Animals; Bicuculline; Blood Pressure; Cats; Cerebral Cortex; Dipyridamole; Doxapram; Naloxone; Penicillins; Receptors, Purinergic; Reference Values; Seizures; Theophylline

1989
Prompt arousal from fentanyl-droperidol-pentobarbital anesthesia in dogs: a preliminary study.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1986, Volume: 50, Issue:2

    Topics: 4-Aminopyridine; Aminopyridines; Anesthesia; Anesthetics; Animals; Arousal; Dogs; Doxapram; Droperidol; Drug Combinations; Fentanyl; Naloxone; Pentobarbital; Yohimbine

1986
Alterations in response to somatic pain associated with anaesthesia. XXII. Nikethamide, doxapram and naloxone.
    British journal of anaesthesia, 1973, Volume: 45, Issue:5

    Topics: Anesthesia; Body Weight; Doxapram; Female; Humans; Meperidine; Morphine; Naloxone; Nikethamide; Pain; Pressure; Time Factors

1973
Modification of the analgesic action of pethidine and morphine by three opiate antagonists, a respiratory stimulant (doxapram) and an analeptic (nikethamide); a study using an experimental pain stimulus in man.
    British journal of pharmacology, 1973, Volume: 48, Issue:2

    Topics: Analgesia; Doxapram; Drug Interactions; Female; Humans; Levallorphan; Male; Meperidine; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Nikethamide; Respiration

1973
Electroencephalographic evidence of arousal in dogs from halothane after doxapram, physostigmine, or naloxone.
    Anesthesiology, 1981, Volume: 55, Issue:4

    Topics: Anesthesia, Inhalation; Animals; Arousal; Cardiovascular System; Dogs; Doxapram; Electroencephalography; Halothane; Naloxone; Physostigmine; Time Factors

1981
NAGD regimen for the coma of drug-related overdose.
    Annals of emergency medicine, 1980, Volume: 9, Issue:7

    Topics: Charcoal; Coma; Doxapram; Drug Therapy, Combination; Glucagon; Humans; Injections, Intravenous; Naloxone; Substance-Related Disorders

1980
NAGD regime [naloxone (Narcan), activated charcoal, glucagon, doxapram (Dopram)] for the coma of drug-related overdoses.
    Clinical toxicology, 1980, Volume: 16, Issue:3

    Topics: Charcoal; Coma; Doxapram; Drug Administration Schedule; Glucagon; Humans; Naloxone; Poisoning

1980