doxapram and morphine

doxapram has been researched along with morphine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199017 (73.91)18.7374
1990's1 (4.35)18.2507
2000's2 (8.70)29.6817
2010's2 (8.70)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Pleuvry, BJ1
Funderbuck, WH; Winnie, AP1
Clement, JG1
Dundee, JW; Gawley, TH; Gupta, PK; Jones, CJ1
Gregoretti, SM; Pleuvry, BJ1
Gasser, JC1
Dundee, JW; Gawley, TH; Jones, CJ1
Cheung, M; Nelson, D; Thangathurai, D1
Fazackerley, EJ; Healy, TE; Modla, CY; Pleuvry, BJ; Prescott, LF; Randall, NP1
Dundee, JW; Gupta, PK4
Jensen, EC; Klemm, WR1
Dundee, JW; Gupta, PK; Jones, CJ; Walker, FS1
Dundee, JW; Gupta, PK; Jones, CJ1
Spector, R1
Gairola, RL; Gupta, PK; Pandley, K1
Guo, YM; Jin, QY; Liang, C; Zhang, YR1
Haji, A; Kimura, S; Ohi, Y1
Authier, S; Boulay, E; Downey, AM; Guerrier, M; Maghezzi, S; Pugsley, M; Smutova, V; St-Pierre, J; Troncy, E1

Reviews

1 review(s) available for doxapram and morphine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

6 trial(s) available for doxapram and morphine

ArticleYear
Role of doxapram in reducing pulmonary complications after major surgery.
    British medical journal, 1976, Jan-17, Volume: 1, Issue:6002

    Topics: Adolescent; Adult; Clinical Trials as Topic; Cough; Doxapram; Female; Humans; Lung Diseases; Male; Middle Aged; Morphine; Naloxone; Oxygen; Postoperative Complications; Sputum

1976
Effect of oral doxapram on morphine-induced changes in the ventilatory response to carbon dioxide.
    British journal of anaesthesia, 1989, Volume: 62, Issue:2

    Topics: Administration, Oral; Adult; Carbon Dioxide; Depression, Chemical; Doxapram; Female; Humans; Male; Morphine; Respiration; Time Factors

1989
Morphine combined with doxapram or naloxone. A study of post-operative pain relief.
    Anaesthesia, 1974, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Aged; Analgesia; Blood Pressure; Body Weight; Clinical Trials as Topic; Doxapram; Drug Interactions; Heart Rate; Humans; Middle Aged; Morphine; Naloxone; Pain; Postoperative Care; Respiration; Time Factors

1974
The effect of an infusion of doxapram on morphine analgesia.
    Anaesthesia, 1974, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Aged; Analgesia; Clinical Trials as Topic; Doxapram; Drug Interactions; Humans; Infusions, Parenteral; Middle Aged; Morphine; Pain; Placebos; Postoperative Complications; Respiration; Time Factors

1974
Opiate analgesia without respiratory depression: a study in postoperative patients.
    British journal of anaesthesia, 1973, Volume: 45, Issue:6

    Topics: Anesthesia, General; Doxapram; Humans; Morphine; Naloxone; Placebos; Postoperative Complications; Respiration

1973
Antagonists of morphine-induced respiratory depression. A study in postoperative patients.
    Anaesthesia, 1980, Volume: 35, Issue:1

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Doxapram; Humans; Levallorphan; Middle Aged; Morphine; Naloxone; Narcotic Antagonists; Pain, Postoperative; Random Allocation; Respiratory Insufficiency; Thiazoles; Time Factors

1980

Other Studies

16 other study(ies) available for doxapram and morphine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
A study of the enhanced toxicity of doxapram in rodents treated with narcotic analgesics.
    British journal of anaesthesia, 1978, Volume: 50, Issue:5

    Topics: Analgesics, Opioid; Animals; Cardiovascular System; Dextromoramide; Doxapram; Drug Synergism; Female; Lethal Dose 50; Mice; Morphine; Rats

1978
Interactions between morphine and doxapram.
    British journal of anaesthesia, 1978, Volume: 50, Issue:2

    Topics: Animals; Doxapram; Drug Interactions; Humans; Mice; Morphine; Rats; Respiration

1978
Effect of ethanol, pentobarbital and morphine on the toxicity of hemicholinium-3 and d-tubocurarine in mice.
    Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 236, Issue:1

    Topics: Animals; Doxapram; Drug Interactions; Ethanol; Hemicholinium 3; Male; Mice; Morphine; Pentobarbital; Prednisolone; Time Factors; Tubocurarine

1978
Interactions between morphine and doxapram in the rabbit and mouse.
    British journal of anaesthesia, 1977, Volume: 49, Issue:4

    Topics: Animals; Carbon Dioxide; Doxapram; Female; Male; Morphine; Rabbits; Respiration; Tidal Volume; Time Factors

1977
Interaction between morphine and doxapram.
    British journal of anaesthesia, 1977, Volume: 49, Issue:9

    Topics: Doxapram; Humans; Male; Morphine; Pentazocine; Respiration

1977
Proceedings: The role of doxapram in the reduction of pulmonary complications following surgery.
    British journal of anaesthesia, 1975, Volume: 47, Issue:8

    Topics: Adolescent; Adult; Doxapram; Humans; Injections, Intravenous; Middle Aged; Morphine; Naloxone; Postoperative Complications; Respiratory Function Tests

1975
Doxapram for respiratory depression after epidural morphine.
    Anaesthesia, 1990, Volume: 45, Issue:1

    Topics: Analgesia, Epidural; Doxapram; Humans; Middle Aged; Morphine; Respiratory Insufficiency

1990
Doxapram.
    Lancet (London, England), 1973, May-19, Volume: 1, Issue:7812

    Topics: Doxapram; Humans; Morphine; Respiration

1973
Clinical evaluation of the analeptic, doxapram, in dogs and cats.
    Journal of the American Veterinary Medical Association, 1967, Mar-01, Volume: 150, Issue:5

    Topics: Anesthesia; Animals; Atropine; Cats; Central Nervous System Stimulants; Dogs; Doxapram; Electrocardiography; Fentanyl; Heart Rate; Morphine; Preanesthetic Medication; Promazine; Spirometry

1967
Alterations in response to somatic pain associated with anaesthesia. XXII. Nikethamide, doxapram and naloxone.
    British journal of anaesthesia, 1973, Volume: 45, Issue:5

    Topics: Anesthesia; Body Weight; Doxapram; Female; Humans; Meperidine; Morphine; Naloxone; Nikethamide; Pain; Pressure; Time Factors

1973
Modification of the analgesic action of pethidine and morphine by three opiate antagonists, a respiratory stimulant (doxapram) and an analeptic (nikethamide); a study using an experimental pain stimulus in man.
    British journal of pharmacology, 1973, Volume: 48, Issue:2

    Topics: Analgesia; Doxapram; Drug Interactions; Female; Humans; Levallorphan; Male; Meperidine; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Nikethamide; Respiration

1973
Treatment of moderate & severe chronic pain syndromes with morphine & adjunctive drugs.
    Journal of the Iowa Medical Society, 1981, Volume: 71, Issue:2

    Topics: Amphetamine; Chronic Disease; Cocaine; Doxapram; Histamine H1 Antagonists; Humans; Morphine; Narcotics; Pain; Phenothiazines; Syndrome

1981
[Analysis of 37 drugs in whole blood by HPLC after solid phase extraction].
    Fa yi xue za zhi, 2006, Oct-15, Volume: 22, Issue:5

    Topics: Chromatography, High Pressure Liquid; Doxapram; Doxepin; Estazolam; Forensic Medicine; Humans; Morphine; Papaverine; Pharmaceutical Preparations; Prazosin; Procaine; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solvents

2006
Reversal of morphine-induced respiratory depression by doxapram in anesthetized rats.
    European journal of pharmacology, 2016, Jun-05, Volume: 780

    Topics: Anesthesia; Animals; Doxapram; Male; Morphine; Phrenic Nerve; Rats; Rats, Wistar; Respiratory Insufficiency

2016
Combined Cardiopulmonary Assessments Using Impedance and Digital Implants in Conscious Freely Moving Cynomolgus Monkeys, Beagle Dogs, and Göttingen Minipigs: Pharmacological Characterization and Social Housing Effects.
    International journal of toxicology, 2021, Volume: 40, Issue:6

    Topics: Amphetamine; Analgesics, Opioid; Animals; Cardiovascular System; Central Nervous System Stimulants; Dexmedetomidine; Dogs; Doxapram; Electric Impedance; Electrocardiography; Macaca fascicularis; Morphine; Swine; Swine, Miniature

2021