Compounds > doxapram

doxapram and alfentanil

doxapram has been researched along with alfentanil in 6 studies

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (16.67)	18.2507
2000's	1 (16.67)	29.6817
2010's	4 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Levy, DM; O'Connor, B; Peacock, JE	1
Dahan, A; Hay, J; McLeod, JF; Okkerse, P; Roozekrans, M; van der Schrier, R	1
Boom, M; Dahan, A; Mooren, R; Olofsen, E; Roozekrans, M; van der Schrier, R	1

Reviews

1 review(s) available for doxapram and alfentanil

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

3 trial(s) available for doxapram and alfentanil

Article	Year
The influence of alfentanil pre-treatment on ventilatory effects of doxapram following induction of anaesthesia with propofol. Acta anaesthesiologica Scandinavica, 1996, Volume: 40, Issue:2 Topics: Adolescent; Adult; Aged; Alfentanil; Anesthesia; Anesthetics, Intravenous; Depression, Chemical; Double-Blind Method; Doxapram; Female; Humans; Male; Middle Aged; Propofol; Respiration; Respiratory System Agents	1996
Two studies on reversal of opioid-induced respiratory depression by BK-channel blocker GAL021 in human volunteers. Anesthesiology, 2014, Volume: 121, Issue:3 Topics: Adolescent; Adult; Alfentanil; Analgesia; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Doxapram; Healthy Volunteers; Hemodynamics; Humans; Large-Conductance Calcium-Activated Potassium Channels; Male; Middle Aged; Potassium Channel Blockers; Respiratory Insufficiency; Triazines	2014
Doxapram-mediated Increase in Cardiac Output Reduces Opioid Plasma Concentrations: A Pharmacokinetic/Pharmacodynamic-Pharmacokinetic/Pharmacodynamic Modeling Study in Healthy Volunteers. Clinical pharmacology and therapeutics, 2017, Volume: 102, Issue:1 Topics: Adult; Alfentanil; Analgesics; Analgesics, Opioid; Blood Pressure; Cardiac Output; Central Nervous System Stimulants; Doxapram; Healthy Volunteers; Humans; Male; Metabolic Clearance Rate; Respiratory Insufficiency; Respiratory System Agents; Treatment Outcome	2017

Other Studies

2 other study(ies) available for doxapram and alfentanil

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010