dothiepin-hydrochloride and docloxythepin

dothiepin-hydrochloride has been researched along with docloxythepin* in 1 studies

Other Studies

1 other study(ies) available for dothiepin-hydrochloride and docloxythepin

Article	Year
Absence of noxious effects of selected neuroleptics in dominant-lethal mutagenesis assay. Mutation research, 1979, Volume: 66, Issue:3 In a dominant-lethal assay in mice the following tricyclic neuroleptics were tested: prothiaden, imipramine, oxyprothepin decanoate and docloxythepin. No dominant-lethal effect was induced by these neuroleptics, even when administered at doses many times as great as clinical doses. The reduced percentages of pregnancies, in females who had copulated with males receiving docloxythepin, observed during and immediately after its administration, were directly connected with marked sedation induced in the males by this neuroleptic. Topics: Animals; Antipsychotic Agents; Dibenzothiepins; Dose-Response Relationship, Drug; Dothiepin; Drug Evaluation, Preclinical; Genetic Techniques; Imipramine; Male; Mice; Mutagens	1979

Article

Year

Absence of noxious effects of selected neuroleptics in dominant-lethal mutagenesis assay.

Mutation research, 1979, Volume: 66, Issue:3

In a dominant-lethal assay in mice the following tricyclic neuroleptics were tested: prothiaden, imipramine, oxyprothepin decanoate and docloxythepin. No dominant-lethal effect was induced by these neuroleptics, even when administered at doses many times as great as clinical doses. The reduced percentages of pregnancies, in females who had copulated with males receiving docloxythepin, observed during and immediately after its administration, were directly connected with marked sedation induced in the males by this neuroleptic.

Topics: Animals; Antipsychotic Agents; Dibenzothiepins; Dose-Response Relationship, Drug; Dothiepin; Drug Evaluation, Preclinical; Genetic Techniques; Imipramine; Male; Mice; Mutagens

1979