Page last updated: 2024-08-25

doripenem and imipenem, anhydrous

doripenem has been researched along with imipenem, anhydrous in 108 studies

Research

Studies (108)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	27 (25.00)	29.6817
2010's	72 (66.67)	24.3611
2020's	9 (8.33)	2.80

Authors

Authors	Studies
Bonomo, RA; Decker, BK; Hujer, AM; Hujer, KM; Perez, F; Rather, PN	1
Appelbaum, PC; Credito, KL; Ednie, LM	1
Citron, DM; Fernandez, HT; Goldstein, EJ; Merriam, CV; Tyrrell, KL; Warren, YA	1
Bush, K; Davies, TA; Flamm, RK; Shang, W	1
Hsueh, PR; Huang, YT; Liao, CH; Lin, HY; Liu, CY; Yen, LC	1
Fujimoto, S; Ike, Y; Okuzumi, K; Tanimoto, K; Tomita, H	1
Brown, NP; Pillar, CM; Sahm, DF; Shah, D; Torres, MK	1
Jacobus, NV; McDermott, LA; Snydman, DR	1
Bell, JM; Castanheira, M; Jones, RN; Mathai, D; Turnidge, JD	1
Thamlikitkul, V; Trakulsomboon, S	1
Bauernfeind, A; Keuleyan, E; Markova, B; Markovska, R; Queenan, AM; Schneider, I	1
Bush, K; Flamm, R; Queenan, AM; Shang, W	1
Aquino, EE; León, CF; Otero, DM; Robledo, IE; Santana, JL; Santé, MI; Vázquez, GJ	1
Flamm, R; Friedland, I; Kaniga, K; Lee, M; Redman, R; Tong, SY	1
Choi, JY; Ko, KS; Lee, MY; Park, YK; Peck, KR; Rhee, JY; Shin, JY; Song, JH	1
Carmeli, Y; Chmelnitsky, I; Goren, MG; Navon-Venezia, S	1
Bied, A; Brown, D; Bush, K; Drusano, GL; Fregeau, C; Kahn, JB; Khashab, M; Kulawy, R; Liu, W; Louie, A; Morrow, B; Nicholson, S; Queenan, AM; Van Scoy, B	1
Appelbaum, PC; Credito, K; Kosowska-Shick, K	1
Bonomo, RA; Distler, AM; Endimiani, A; Hornick, JM; Hujer, AM; Hujer, KM; Papp-Wallace, KM; Taracila, M	1
Bernabeu, S; Nordmann, P; Poirel, L; Revathi, G	1
Fernando, DM; Gorityala, BK; Goswami, S; Guchhait, G; Kumar, A; Schweizer, F; Zhanel, GG	1
Bojkovic, J; Dean, CR; Dobler, M; Dzink-Fox, J; Glick, M; Hamann, LG; Kerrigan, J; Lanieri, L; Lenoir, F; Lilly, MD; Liu, E; Lu, Y; McKenney, D; Nunez, J; Osborne, C; Parker, DT; Patnaik, A; Peng, Y; Piizzi, G; Ranjitkar, S; Sprague, ER; Tommasi, R; Wang, B; Wang, H; Wattanasin, S; Xie, L; Yang, X; Yu, D	1
Bermingham, A; Blais, J; Capka, V; Cariaga, T; Casarez, A; Colvin, R; Dean, CR; Fekete, A; Gong, W; Growcott, E; Guo, H; Jones, AK; Li, C; Li, F; Lin, X; Lindvall, M; Lopez, S; McKenney, D; Metzger, L; Moser, HE; Prathapam, R; Rasper, D; Reck, F; Rudewicz, P; Sethuraman, V; Shaul, J; Shen, X; Simmons, RL; Tang, D; Tashiro, K; Tjandra, M; Turner, N; Uehara, T; Vitt, C; Whitebread, S; Yifru, A; Zang, X; Zhu, Q	1
Bethel, CR; Bonomo, RA; Cmolik, A; Domitrovic, TN; Goldberg, JA; Hoyer, D; Hujer, AM; Hujer, KM; Jacobs, MR; Kreiswirth, BM; Kumar, V; Logan, LK; Marshall, EK; Marshall, SH; Nguyen, H; O'Shea, M; Papp-Wallace, KM; Perez, F; Plummer, MS; Rudin, SD; Spencer, EJ; van den Akker, F; van Duin, D	1
Nagayama, A; Nomura, S	1
Engel, AE; Glass, D; Li, C; Wexler, HM	1
Fujimoto, S; Ike, Y; Sakyo, S; Tanimoto, K; Tomita, H	1
Dilay, L; Hoban, DJ; Karlowsky, JA; Noreddin, AM; Rubinstein, E; Thomson, K; Wiebe, R; Zhanel, GG	1
Katsube, T; Yamano, Y; Yano, Y	1
Lister, PD	1
Nicolau, DP	1
Joseph, J; Rodvold, KA	1
Chastre, J; Friedland, I; Kaniga, K; Lee, M; Prokocimer, P; Wunderink, R	1
Gilbert, D	1
Friedland, I; Gast, C; Ingham, M; Ketter, N; Lee, M; Merchant, S; Nathwani, D; Quintana, A	1
Alba, V; Marti, S; Sánchez-Céspedes, J; Vila, J	1
Porath, AD	1
Cleveland, KO; Gelfand, MS; Mazumder, SA	1
Restrepo, MI	1
Amin, A	1
Akhras, K; DeLong, K; Ingham, M; McGarry, LJ; Merchant, S; Nathwani, D; Pawar, V; Thompson, D; Weinstein, MC	1
Esterly, JS; Malczynski, M; Qi, C; Scheetz, MH	1
Gast, C; Ketter, N; Kollef, MH; Merchant, S; Nathwani, D; Quintana, A	1
Dubreuil, L; Jean-Pierre, H; Mahieux, S; Marchandin, H; Miara, A; Muller-Serieys, C; Neut, C; Soussy, CJ	1
Chen, J; Mody, SH; Shorr, AF; Zilberberg, MD	1
Crandon, JL; Keel, RA; Nicolau, DP; Sutherland, CA	1
Cantón, R; García, A; Gimeno, C; Gobernado, M	1
Boutoille, D; Bretonnière, C; Caillon, J; Guitton, C; Jacqueline, C; Le Mabecque, V; Miégeville, AF; Potel, G; Villers, D	1
Cassettari, M; Chongthaleong, A; Christiansen, KJ; Cooper, D; Flamm, R; Garcia, J; Hsu, L; Ip, M; Ker, HB; Kiratisin, P; Mendoza, M; Morrissey, I; Okolo, P; Quintana, A; Redjeki, IS	1
Ko, KS; Lee, H; Peck, KR; Song, JH	1
Abbanat, D; Barron, A; Bunting, RA; Fernandez, J; Flamm, RK; Hall, L; Hilliard, JJ; Lynch, AS; Melton, JL; Ward, CK	1
Gomersall, C; Kuti, JL; Kwa, A; Montakantikul, P; Nicolau, DP; Roberts, JA	1
Appelbaum, PC; Armstrong, ES; Kosowska-Shick, K; Kubo, A; Lin, G; Pankuch, GA	1
Chiang, T; Colon-Urban, R; Eng, RH; Gomez, E; Huang, DB; Mariano, N; Urban, C	1
Flamm, RK; Korten, V; Laeuffer, JM; Morrissey, I; Mutters, R; Nordmann, P; Picazo, JJ; Quintana, A; Seak, JC	1
Apisarnthanarak, A; Apisarnthanarak, P; Kiratisin, P; Mundy, LM	1
Goessens, WH; Mol, M; Pitout, JD; van der Bij, AK; van Westreenen, M	1
Akalın, H; Akova, M; Arman, D; Aygen, B; Başaran, S; Bayramoğlu, G; Dizbay, M; Dokuzoğuz, B; Eraksoy, H; Esener, H; Hasçelik, G; Köksal, I; Korten, V; Oğünç, D; Sınırtaş, M; Söyletir, G; Sümerkan, B; Tünger, A; Ulusoy, S; Yalçın, AN	1
Cabot, G; Cantón, R; del Campo, R; García-Castillo, M; Juan, C; Mulet, X; Oliver, A; Riera, E	1
Amsler, K; Davies, TA; Flamm, RK; He, W; Lynch, AS; Marie Queenan, A; Morrow, BJ; Pillar, C; Shang, W	1
Akers, KS; Beckius, ML; Calvano, T; Hospenthal, DR; Markelz, AE; Mende, K; Murray, CK; Yu, X; Zera, WC	1
Baek, JY; Kang, CI; Ko, KS; Peck, KR; Song, JH	1
Bonomo, RA; Endimiani, A; Papp-Wallace, KM; Taracila, MA	1
Boutoille, D; Bretonnière, C; Caillon, J; Desessard, C; Guitton, C; Jacqueline, C; Le Mabecque, V; Miégeville, AF; Potel, G; Villers, D	1
Firsov, AA; Gilbert, D; Greer, K; Portnoy, YA; Zinner, SH	1
Hagihara, M; Kuti, JL; Nicolau, DP	1
Decker-Burgard, S; Laeuffer, J; Morrissey, I; Mutters, R; Seifert, H; Valenza, G	1
Antunes, NT; Frase, H; Toth, M; Vakulenko, SB; Vakulenko, V	1
Chen, CC; Cheng, KC; Chiang, SR; Chiu, YH; Chuang, YC; Ko, WC; Ku, YH; Tang, HJ; Zhang, CC	1
Dundar, D; Kasap, M; Kolayli, F; Torol, S; Vahaboglu, H	1
Chang, SC; Dong, SX; Wang, JT	1
Keel, RA; Kiratisin, P; Nicolau, DP	1
Chastre, J; Cirillo, I; Clavel, M; Kaniga, K; Kimko, H; Kollef, MH; Michiels, B; Redman, R; Restrepo, MI	1
Colakoğlu, S; Durmaz, S; Ekincioğlu, P; Perçin, D	1
Adamski, P; Bulanda, M; Drzewiecki, A; Sodo, A; Talaga, K	1
Dantier, C; Desarbre, E; Gebhardt, K; Hofer, B; Page, MG; Schmitt-Hoffmann, A	1
Kaniga, K; Lee, M; Redman, R; Rice, DA	1
Goff, DA; Nicolau, DP	1
Guzek, A; Korzeniewski, K; Nitsch-Osuch, A; Prokop, E; Rybicki, Z	1
Kirikae, T; Miyoshi-Akiyama, T; Shimada, K; Shimojima, M; Tada, T	1
Kurtinecz, M; Li, G; Mitrani-Gold, FS; Mundy, LM; Singh, KP; Tomayko, JF; Wetherington, J	1
Arthur, M; Cordillot, M; Dubée, V; Dubost, L; Hugonnet, JE; Mainardi, JL; Marie, A; Triboulet, S	1
Aubry, A; Bréchot, N; Brisson, H; Brossier, F; Chastre, J; Combes, A; Jarlier, V; Lu, Q; Luyt, CE; Micaelo, M; Rouby, JJ; Trouillet, JL	1
Cannon, JP; Clark, NM; Grim, SA; Lee, TA; Setlak, P	1
Igarashi, Y; Inui, K; Ohara, H; Ryozawa, S; Tazuma, S; Tsuyuguchi, T	1
Abe, J; Fujita, A; Hino, M; Hirose, A; Kakeya, H; Kaneko, Y; Nakaie, K; Nakamura, Y; Okada, Y; Takizawa, E; Yamada, K	1
Srinivas, NR	1
Boutoille, D; Bretonnière, C; Caillon, J; Guitton, C; Jacqueline, C; Maitte, A; Potel, G	1
Mirza, IA; Wali, N	1
Arakawa, Y; Jin, W; Kimura, K; Kurosaki, H; Mori, S; Wachino, J; Yamaguchi, Y	1
Abdollahi, A; Aliramezani, A; Boroumand, MA; Douraghi, M; Ghalavand, Z; Ghourchian, S; Mohammadzadeh, M; Nateghi Rostami, M; Rahbar, M; Zeraati, H	1
Aubry, A; Chastre, J; Crandon, JL; Luyt, CE; Nicolau, DP	1
Hu, YF; Liu, CP; Shih, SC; Wang, NY	1
Ajao, AO; Albrecht, JS; Furuno, JP; Harris, AD; Johnson, JK; Pineles, LL; Robinson, GL; Thom, KA; Zhao, L	1
Bonomo, RA; Harper, TM; June, CM; Leonard, DA; Powers, RA; Taracila, MA	1
Aubry, A; Bréchot, N; Brossier, F; Jarlier, V; Lu, Q; Luyt, CE; Micaëlo, M; Monsel, A	1
Antunes, NT; Smith, CA; Stewart, NK; Toth, M; Vakulenko, SB	1
Abdalhamid, B; Fowler, RC; Hanson, ND; Harrison, LB; Selmecki, A	1
Smith, CA; Stewart, NK; Toth, M; Vakulenko, SB	1
Fu, L; Li, H; Li, X; Liu, J; Luo, S; Wan, Z; Wang, Y; Wu, X; Xie, X; Zhao, Z	1
Ikebuchi, K; Imai, K; Kawamura, T; Kodana, M; Maeda, T; Maesaki, S; Mitsutake, K; Murakami, T; Ogane, K; Onodera, A; Sakai, J; Takeuchi, S; Tarumoto, N	1
Allison, N; Crisostomo, C; Lynch, B; Padilla, M; Quach-Cu, J; Reinke, RA	1
Baba, T; Boucher, HW; Chambers, HF; Collyar, D; Dai, W; Doernberg, SB; Evans, SR; Fowler, VG; Gelone, SP; Hamasaki, T; Hill, C; Holland, TL; Howard-Anderson, J; Kinamon, T; Mariano, D; Nambiar, S; Rubin, D	1
Ishaq, M; Zahra, N; Zeshan, B	1
Dargahi, Z; Etemad, A; Ghasemian, E; Hashemian, M; Kaviar, VH; Lohrasbi, A; Saadh, MJ	1
George Priya Doss, C; Gopikrishnan, M	1
Hsueh, PR; Ko, WC; Lee, YL	1

Reviews

9 review(s) available for doripenem and imipenem, anhydrous

Article	Year
Global challenge of multidrug-resistant Acinetobacter baumannii. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10 Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Cross Infection; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Humans	2007
Comparative review of the carbapenems. Drugs, 2007, Volume: 67, Issue:7 Topics: Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Carbapenems; Doripenem; Ertapenem; Humans; Imipenem; Meropenem; Thienamycins	2007
Carbapenems in the USA: focus on doripenem. Expert review of anti-infective therapy, 2007, Volume: 5, Issue:5 Topics: Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Carbapenems; Clinical Trials as Topic; Doripenem; Drug Resistance, Multiple, Bacterial; Ertapenem; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Structure-Activity Relationship; Thienamycins; United States	2007
Carbapenems: a potent class of antibiotics. Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:1 Topics: Anti-Bacterial Agents; Bacteria; beta-Lactams; Carbapenems; Clinical Trials as Topic; Doripenem; Ertapenem; Humans; Imipenem; Meropenem; Molecular Structure; Structure-Activity Relationship; Thienamycins	2008
The role of carbapenems in the treatment of severe nosocomial respiratory tract infections. Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactams; Carbapenems; Cross Infection; Doripenem; Drug Administration Schedule; Drug Resistance, Multiple, Bacterial; Ertapenem; Humans; Imipenem; Meropenem; Patient Selection; Pneumonia, Bacterial; Respiratory Tract Infections; Severity of Illness Index; Thienamycins; Treatment Outcome	2008
Carbapenems: past, present, and future. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:11 Topics: Anti-Bacterial Agents; beta-Alanine; beta-Lactams; Carbapenems; Cilastatin; Cilastatin, Imipenem Drug Combination; Doripenem; Drug Combinations; Ertapenem; Humans; Imipenem; Thienamycins	2011
Systematic review and meta-analysis of antimicrobial treatment effect estimation in complicated urinary tract infection. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:11 Topics: Anti-Bacterial Agents; Carbapenems; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Databases, Bibliographic; Doripenem; Drug Combinations; Female; Humans; Imipenem; Levofloxacin; Male; Research Design; Treatment Outcome; Urinary Tract Infections	2013
The risk of seizures among the carbapenems: a meta-analysis. The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:8 Topics: Adult; Anti-Bacterial Agents; beta-Lactams; Carbapenems; Child; Cilastatin; Cilastatin, Imipenem Drug Combination; Doripenem; Drug Combinations; Ertapenem; Humans; Imipenem; Meropenem; Risk; Seizures; Thienamycins	2014
The Status of Carbapenem Resistance in Cystic Fibrosis: A Systematic Review and Meta-Analysis. The Yale journal of biology and medicine, 2022, Volume: 95, Issue:4 Topics: Anti-Bacterial Agents; Carbapenems; Cystic Fibrosis; Doripenem; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa	2022

Trials

7 trial(s) available for doripenem and imipenem, anhydrous

Article	Year
Efficacy and safety of intravenous infusion of doripenem versus imipenem in ventilator-associated pneumonia: a multicenter, randomized study. Critical care medicine, 2008, Volume: 36, Issue:4 Topics: Aged; Anti-Bacterial Agents; APACHE; Carbapenems; Doripenem; Female; Hospital Mortality; Humans; Imipenem; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged; Pneumonia, Ventilator-Associated; Treatment Outcome	2008
"The truth, if it exists, is in the details". Critical care medicine, 2008, Volume: 36, Issue:4 Topics: Amikacin; Anti-Bacterial Agents; Carbapenems; Doripenem; Humans; Imipenem; Pneumonia, Ventilator-Associated; Severity of Illness Index; Treatment Outcome	2008
Hospital resource utilization with doripenem versus imipenem in the treatment of ventilator-associated pneumonia. Clinical therapeutics, 2008, Volume: 30, Issue:4 Topics: Anti-Bacterial Agents; Carbapenems; Costs and Cost Analysis; Doripenem; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Hospital Costs; Humans; Imipenem; Infusions, Intravenous; Length of Stay; Male; Middle Aged; Pneumonia, Ventilator-Associated; Survival Rate; Treatment Outcome	2008
A randomized trial of 7-day doripenem versus 10-day imipenem-cilastatin for ventilator-associated pneumonia. Critical care (London, England), 2012, Nov-13, Volume: 16, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Carbapenems; Cilastatin; Doripenem; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Imipenem; Infusions, Intravenous; Male; Middle Aged; Pneumonia, Ventilator-Associated; Young Adult	2012
Activity of doripenem versus comparators in subjects with baseline bacteraemia in six pooled phase 3 clinical trials. International journal of antimicrobial agents, 2013, Volume: 41, Issue:4 Topics: Anti-Bacterial Agents; Bacteremia; Carbapenems; Cross Infection; Doripenem; Female; Humans; Imipenem; Intraabdominal Infections; Male; Meropenem; Ofloxacin; Pneumonia; Thienamycins; Treatment Outcome; Urinary Tract Infections	2013
Imipenem, meropenem, or doripenem to treat patients with Pseudomonas aeruginosa ventilator-associated pneumonia. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:3 Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Disk Diffusion Antimicrobial Tests; Doripenem; Female; Humans; Imipenem; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Pneumonia, Ventilator-Associated; Pseudomonas Infections; Thienamycins	2014
Clinical efficacy of intravenous doripenem in patients with acute biliary tract infection: a multicenter, randomized, controlled trial with imipenem/cilastatin as comparator. Journal of gastroenterology, 2015, Volume: 50, Issue:2 Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Body Temperature; C-Reactive Protein; Carbapenems; Cholangitis; Cholecystitis, Acute; Cilastatin; Cilastatin, Imipenem Drug Combination; Doripenem; Drug Combinations; Female; Humans; Imipenem; Infusions, Intravenous; Male; Middle Aged; Treatment Outcome; Young Adult	2015

Other Studies

92 other study(ies) available for doripenem and imipenem, anhydrous

Article	Year
Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:1 Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Carbapenems; Colony Count, Microbial; Doripenem; Humans; Microbial Sensitivity Tests	2008
In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2 Topics: Anti-Bacterial Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; Carbapenems; Diabetic Foot; Doripenem; Humans; Microbial Sensitivity Tests	2008
Affinity of doripenem and comparators to penicillin-binding proteins in Escherichia coli and Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Carbapenems; Doripenem; Escherichia coli; Escherichia coli Proteins; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Pseudomonas aeruginosa	2008
Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:9 Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Bacteroides fragilis; Bacteroides Infections; Blood; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Taiwan	2008
Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa, but use of the high-potency drug doripenem inhibits mutant formation. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10 Topics: Base Sequence; beta-Lactam Resistance; Carbapenems; DNA Primers; DNA, Bacterial; Doripenem; Fluoroquinolones; Genes, Bacterial; Humans; In Vitro Techniques; Meropenem; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins	2008
In vitro activity of doripenem, a carbapenem for the treatment of challenging infections caused by gram-negative bacteria, against recent clinical isolates from the United States. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:12 Topics: Anti-Bacterial Agents; Carbapenems; Doripenem; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; United States	2008
In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:12 Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Bacteroides fragilis; Carbapenems; Doripenem; Drug Resistance, Bacterial; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests	2008
Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18). Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3 Topics: Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Humans; India; Microbial Sensitivity Tests; Molecular Sequence Data; Prevalence; Pseudomonas aeruginosa; Ribotyping	2009
In vitro activity of doripenem against Burkholderia pseudomallei. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7 Topics: Anti-Bacterial Agents; Burkholderia pseudomallei; Carbapenems; Doripenem; Microbial Sensitivity Tests	2009
New variant of CTX-M-type extended-spectrum beta-lactamases, CTX-M-71, with a Gly238Cys substitution in a Klebsiella pneumoniae isolate from Bulgaria. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10 Topics: Anti-Bacterial Agents; beta-Lactamases; Bulgaria; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data	2009
Hydrolysis and inhibition profiles of beta-lactamases from molecular classes A to D with doripenem, imipenem, and meropenem. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; Carbapenems; Doripenem; Enzyme Inhibitors; Hydrolysis; Imipenem; Kinetics; Meropenem; Microbial Sensitivity Tests; Thienamycins	2010
Detection of KPC in Acinetobacter spp. in Puerto Rico. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3 Topics: Acinetobacter; Acinetobacter Infections; Adult; Aged; Aged, 80 and over; beta-Lactam Resistance; beta-Lactamases; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Population Surveillance; Puerto Rico	2010
Worldwide experience with the use of doripenem against extended-spectrum-beta-lactamase-producing and ciprofloxacin-resistant Enterobacteriaceae: analysis of six phase 3 clinical studies. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Ciprofloxacin; Clinical Trials, Phase III as Topic; Doripenem; Enterobacteriaceae; Enterobacteriaceae Infections; Global Health; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prevalence	2010
KPC-producing extreme drug-resistant Klebsiella pneumoniae isolate from a patient with diabetes mellitus and chronic renal failure on hemodialysis in South Korea. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Aged; beta-Lactamases; Diabetic Nephropathies; Humans; Kidney Failure, Chronic; Klebsiella Infections; Klebsiella pneumoniae; Male; Renal Dialysis; Republic of Korea	2010
Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6 Topics: Academic Medical Centers; Bacterial Proteins; Base Sequence; beta-Lactamases; Carbapenems; DNA Primers; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Infections; Humans; In Vitro Techniques; Israel; Microbial Sensitivity Tests; Molecular Epidemiology; Plasmids; Time Factors	2010
Impact of different carbapenems and regimens of administration on resistance emergence for three isogenic Pseudomonas aeruginosa strains with differing mechanisms of resistance. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Doripenem; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Imipenem; In Vitro Techniques; Microbial Sensitivity Tests; Mutation; Porins; Proportional Hazards Models; Pseudomonas aeruginosa; Pseudomonas Infections; Time Factors	2010
Mutant prevention concentrations of four carbapenems against gram-negative rods. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6 Topics: Acinetobacter baumannii; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Carbapenems; Doripenem; Drug Resistance, Bacterial; Ertapenem; Escherichia coli; Genes, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Imipenem; In Vitro Techniques; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Mutation; Phenotype; Pseudomonas aeruginosa; Thienamycins	2010
Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7 Topics: Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cephalosporinase; Clavulanic Acid; Computer Simulation; Enzyme Inhibitors; Hydrogen Bonding; Kinetics; Microbial Sensitivity Tests; Molecular Structure; Mutagenesis, Site-Directed; Penicillanic Acid; Protein Structure, Secondary; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Sulbactam; Tazobactam	2010
Detection of NDM-1-producing Klebsiella pneumoniae in Kenya. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:2 Topics: Adult; Aged; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cross Infection; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Female; Humans; Kenya; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Middle Aged; Polymerase Chain Reaction	2011
Hybrid Antibiotic Overcomes Resistance in P. aeruginosa by Enhancing Outer Membrane Penetration and Reducing Efflux. Journal of medicinal chemistry, 2016, 09-22, Volume: 59, Issue:18 Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Moxifloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2016
Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC. Journal of medicinal chemistry, 2017, 06-22, Volume: 60, Issue:12 Topics: Amidohydrolases; Animals; Anti-Bacterial Agents; Chemistry Techniques, Synthetic; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors; Female; Hep G2 Cells; Humans; K562 Cells; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Docking Simulation; Pseudomonas aeruginosa; Pseudomonas Infections; Structure-Activity Relationship	2017
Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228. Bioorganic & medicinal chemistry letters, 2018, 02-15, Volume: 28, Issue:4 Topics: Animals; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenem-Resistant Enterobacteriaceae; CHO Cells; Cricetulus; Drug Stability; Escherichia coli; Female; Humans; Meropenem; Mice; Microbial Sensitivity Tests; Molecular Structure; Monobactams; Pseudomonas aeruginosa; Receptors, GABA-A; Seizures; Structure-Activity Relationship; Thienamycins	2018
A γ-Lactam Siderophore Antibiotic Effective against Multidrug-Resistant Gram-Negative Bacilli. Journal of medicinal chemistry, 2020, 06-11, Volume: 63, Issue:11 Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Half-Life; Lactams; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Penicillin-Binding Proteins; Pseudomonas aeruginosa; Siderophores	2020
In vitro antibacterial activity of S-4661, a new parenteral carbapenem, against urological pathogens isolated from patients with complicated urinary tract infections. Journal of chemotherapy (Florence, Italy), 2002, Volume: 14, Issue:2 Topics: Anti-Bacterial Agents; Bacteria; Carbapenems; Ceftazidime; Doripenem; Humans; Imipenem; In Vitro Techniques; Meropenem; Microbial Sensitivity Tests; Thienamycins; Urinary Tract Infections	2002
In vitro activities of doripenem and comparator agents against 364 anaerobic clinical isolates. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:10 Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; beta-Lactams; Carbapenems; Doripenem; Ertapenem; Humans; Imipenem; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Ofloxacin; Thienamycins	2005
Potency of carbapenems for the prevention of carbapenem-resistant mutants of Pseudomonas aeruginosa: the high potency of a new carbapenem doripenem. The Journal of antibiotics, 2006, Volume: 59, Issue:4 Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Carbapenems; Colony Count, Microbial; Doripenem; Drug Resistance, Bacterial; Electrophoresis, Polyacrylamide Gel; Gene Expression; Imipenem; Meropenem; Molecular Weight; Mutation; Pseudomonas aeruginosa; Thienamycins	2006
Pharmacokinetic-pharmacodynamic modeling and simulation for in vivo bactericidal effect in murine infection model. Journal of pharmaceutical sciences, 2008, Volume: 97, Issue:4 Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Bacterial Infections; Carbapenems; Cilastatin; Disease Models, Animal; Doripenem; Female; Imipenem; Meropenem; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Models, Biological; Thienamycins	2008
In vitro activity of doripenem against Acinetobacter baumannii clinical isolates. International journal of antimicrobial agents, 2009, Volume: 33, Issue:2 Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Doripenem; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Thienamycins	2009
Lucasti et al in the May 2008 issue of Clinical Therapeutics. Clinical therapeutics, 2008, Volume: 30, Issue:10 Topics: Abdominal Abscess; Anti-Bacterial Agents; Bacterial Infections; Carbapenems; Doripenem; Humans; Imipenem; Meropenem; Thienamycins	2008
Successful treatment with doripenem and tobramycin of ventriculitis due to imipenem- and meropenem-resistant Pseudomonas aeruginosa. The Journal of antimicrobial chemotherapy, 2009, Volume: 63, Issue:6 Topics: Adult; Anti-Bacterial Agents; Carbapenems; Doripenem; Drug Resistance, Bacterial; Encephalitis; Humans; Imipenem; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2009
Efficacy of intravenous infusion of doripenem. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009, Aug-15, Volume: 49 Suppl 1 Topics: Carbapenems; Cross Infection; Doripenem; Humans; Imipenem; Infusions, Intravenous; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Ventilator-Associated	2009
Clinical and economic consequences of ventilator-associated pneumonia. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009, Aug-15, Volume: 49 Suppl 1 Topics: Anti-Bacterial Agents; Carbapenems; Cross Infection; Doripenem; Health Care Costs; Hospital Mortality; Humans; Imipenem; Intensive Care Units; Length of Stay; Pneumonia, Ventilator-Associated; Pseudomonas aeruginosa; Severity of Illness Index	2009
Economic assessment of doripenem versus imipenem in the treatment of ventilator-associated pneumonia. Journal of medical economics, 2010, Volume: 13, Issue:1 Topics: Anti-Bacterial Agents; Carbapenems; Cost-Benefit Analysis; Decision Support Techniques; Doripenem; Hospitalization; Humans; Imipenem; Intensive Care Units; Length of Stay; Middle Aged; Models, Economic; Monte Carlo Method; Pneumonia, Ventilator-Associated; Probability; Respiration, Artificial; Time Factors; United States	2010
Predictability of doripenem susceptibility in Acinetobacter baumannii isolates based on other carbapenem susceptibilities and bla OXA gene status. Pharmacotherapy, 2010, Volume: 30, Issue:4 Topics: Acinetobacter baumannii; beta-Lactamases; Carbapenems; Doripenem; Genotype; Hospitals; Humans; Imipenem; Meropenem; Oxytocin; Polymerase Chain Reaction; Thienamycins	2010
Medical resource utilization among patients with ventilator-associated pneumonia: pooled analysis of randomized studies of doripenem versus comparators. Critical care (London, England), 2010, Volume: 14, Issue:3 Topics: Adult; Aged; Anti-Bacterial Agents; Carbapenems; Clinical Trials, Phase III as Topic; Doripenem; Female; Health Resources; Humans; Imipenem; Length of Stay; Male; Middle Aged; Multicenter Studies as Topic; Penicillanic Acid; Piperacillin; Pneumonia, Ventilator-Associated; Prospective Studies; Randomized Controlled Trials as Topic; Tazobactam; Treatment Outcome	2010
[Activity of doripenem against anaerobic bacteria]. Pathologie-biologie, 2011, Volume: 59, Issue:2 Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; Bacteroides fragilis; Carbapenems; Doripenem; Drug Resistance, Microbial; Drug Resistance, Multiple, Bacterial; Gram-Positive Bacteria; Humans; Imipenem; Microbial Sensitivity Tests	2011
Cost-effectiveness model of empiric doripenem compared with imipenem-cilastatin in ventilator-associated pneumonia. Surgical infections, 2010, Volume: 11, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Carbapenems; Cilastatin; Cilastatin, Imipenem Drug Combination; Cost-Benefit Analysis; Doripenem; Drug Combinations; Humans; Imipenem; Length of Stay; Middle Aged; Pneumonia, Ventilator-Associated; Pseudomonas aeruginosa; Pseudomonas Infections; Quality-Adjusted Life Years; Young Adult	2010
Stability of doripenem, imipenem and meropenem at elevated room temperatures. International journal of antimicrobial agents, 2011, Volume: 37, Issue:2 Topics: Anti-Bacterial Agents; Carbapenems; Doripenem; Drug Stability; Drug Storage; Imipenem; Meropenem; Temperature; Thienamycins; Time Factors	2011
[Comparative activity of doripenem, meropenem, and imipenem in recent clinical isolates obtained during the COMPACT-Spain epidemiological surveillance study]. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2010, Volume: 23, Issue:3 Topics: Acinetobacter Infections; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Carbapenems; Doripenem; Enterobacteriaceae Infections; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Pseudomonas Infections; Spain; Thienamycins	2010
Efficacy of doripenem in the treatment of Pseudomonas aeruginosa experimental pneumonia versus imipenem and meropenem. The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:11 Topics: Animals; Anti-Bacterial Agents; Bacterial Load; Blood; Carbapenems; Disease Models, Animal; Doripenem; Female; Imipenem; Infusions, Intravenous; Lung; Meropenem; Plasma; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Spleen; Thienamycins; Treatment Outcome	2010
In vitro activity of doripenem and other carbapenems against contemporary Gram-negative pathogens isolated from hospitalised patients in the Asia-Pacific region: results of the COMPACT Asia-Pacific Study. International journal of antimicrobial agents, 2010, Volume: 36, Issue:6 Topics: Anti-Bacterial Agents; Asia; Carbapenems; Doripenem; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Pacific Islands; Thienamycins	2010
Antimicrobial activity of doripenem and other carbapenems against gram-negative pathogens from Korea. Microbial drug resistance (Larchmont, N.Y.), 2011, Volume: 17, Issue:1 Topics: Anti-Bacterial Agents; Bacteremia; Carbapenems; Doripenem; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Imipenem; Korea; Meropenem; Microbial Sensitivity Tests; Republic of Korea; Thienamycins; Urinary Tract Infections	2011
Comparative effects of carbapenems on bacterial load and host immune response in a Klebsiella pneumoniae murine pneumonia model. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:2 Topics: Animals; Anti-Bacterial Agents; Bacterial Load; beta-Lactamases; Carbapenems; Cytokines; Disease Models, Animal; Doripenem; Female; Humans; Imipenem; Klebsiella Infections; Klebsiella pneumoniae; Lung; Meropenem; Mice; Mice, Inbred C3H; Microbial Sensitivity Tests; Pneumonia, Bacterial; Thienamycins; Treatment Outcome	2011
Pharmacodynamic profiling of intravenous antibiotics against prevalent Gram-negative organisms across the globe: the PASSPORT Program-Asia-Pacific Region. International journal of antimicrobial agents, 2011, Volume: 37, Issue:3 Topics: Anti-Bacterial Agents; Asia; Australia; Carbapenems; Doripenem; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Imipenem; Injections, Intravenous; Intensive Care Units; Meropenem; Microbial Sensitivity Tests; Monte Carlo Method; Thienamycins	2011
Activity of ACHN-490 tested alone and in combination with other agents against Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:5 Topics: Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Doripenem; Imipenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa	2011
Phenotypic and genotypic screening and clonal analysis of carbapenem-resistant Klebsiella pneumoniae at a single hospital. Microbial drug resistance (Larchmont, N.Y.), 2011, Volume: 17, Issue:2 Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacterial Typing Techniques; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Carbapenems; DNA, Bacterial; Doripenem; Electrophoresis, Gel, Pulsed-Field; Ertapenem; Genotype; Hospitals, Urban; Humans; Imipenem; Klebsiella Infections; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Phylogeny; Polymerase Chain Reaction; Sensitivity and Specificity; Thienamycins; United States	2011
Comparative activity of carbapenem testing: the COMPACT study. The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:5 Topics: Africa; Anti-Bacterial Agents; Carbapenems; Cross Infection; Doripenem; Europe; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Middle East; Thienamycins	2011
Gastrointestinal selective capacity of doripenem, meropenem, and imipenem for carbapenem-resistant gram-negative bacilli in treated patients with pneumonia. Infection control and hospital epidemiology, 2011, Volume: 32, Issue:4 Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Aged; Anti-Bacterial Agents; Carbapenems; Doripenem; Drug Resistance, Bacterial; Female; Gram-Negative Bacterial Infections; Humans; Imipenem; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections; Random Allocation; Rectum; Stenotrophomonas maltophilia; Thienamycins	2011
The laboratory diagnosis of Pseudomonas aeruginosa that produce metallo-β-lactamases in a Dutch tertiary care centre. Scandinavian journal of infectious diseases, 2011, Volume: 43, Issue:8 Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Disk Diffusion Antimicrobial Tests; Doripenem; Edetic Acid; Humans; Imipenem; Laboratories; Meropenem; Microbial Sensitivity Tests; Netherlands; Pseudomonas aeruginosa; Pseudomonas Infections; Reproducibility of Results; Thienamycins	2011
[Comparative evaluation of in vitro activities of carbapenems against gram-negative pathogens: Turkish data of COMPACT study]. Mikrobiyoloji bulteni, 2011, Volume: 45, Issue:2 Topics: Anti-Bacterial Agents; Bacteremia; Carbapenems; Cross Infection; Doripenem; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Imipenem; Intensive Care Units; Meropenem; Microbial Sensitivity Tests; Pneumonia, Bacterial; Thienamycins; Turkey	2011
Pseudomonas aeruginosa carbapenem resistance mechanisms in Spain: impact on the activity of imipenem, meropenem and doripenem. The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:9 Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Doripenem; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Imipenem; Meropenem; Microbial Sensitivity Tests; Molecular Epidemiology; Mutation; Plasmids; Population Surveillance; Porins; Pseudomonas aeruginosa; Pseudomonas Infections; Reverse Transcriptase Polymerase Chain Reaction; Spain; Thienamycins	2011
Longitudinal survey of carbapenem resistance and resistance mechanisms in Enterobacteriaceae and non-fermenters from the USA in 2007-09. The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:10 Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Doripenem; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Genotype; Imipenem; Klebsiella pneumoniae; Longitudinal Studies; Meropenem; Microbial Sensitivity Tests; Porins; Pseudomonas aeruginosa; Thienamycins; United States	2011
Carbapenem susceptibility testing errors using three automated systems, disk diffusion, Etest, and broth microdilution and carbapenem resistance genes in isolates of Acinetobacter baumannii-calcoaceticus complex. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:10 Topics: Acinetobacter baumannii; Acinetobacter calcoaceticus; Acinetobacter Infections; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Doripenem; Drug Resistance, Bacterial; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Thienamycins	2011
In vitro antibacterial activities of doripenem, imipenem, and meropenem against recent Streptococcus pneumoniae isolates. Diagnostic microbiology and infectious disease, 2011, Volume: 71, Issue:3 Topics: Anti-Bacterial Agents; Carbapenems; Doripenem; Drug Resistance, Bacterial; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Streptococcus pneumoniae; Thienamycins	2011
Evaluation of doripenem in an experimental model of resistant Pseudomonas aeruginosa pneumonia. The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:3 Topics: Animals; Anti-Bacterial Agents; Bacterial Load; beta-Lactam Resistance; Carbapenems; Colony Count, Microbial; Disease Models, Animal; Doripenem; Humans; Imipenem; Lung; Meropenem; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Thienamycins; Treatment Outcome	2012
Comparative pharmacodynamics and antimutant potentials of doripenem and imipenem with ciprofloxacin-resistant Pseudomonas aeruginosa in an in vitro model. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:3 Topics: Anti-Bacterial Agents; Area Under Curve; Carbapenems; Ciprofloxacin; Doripenem; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Humans; Imipenem; Microbial Sensitivity Tests; Models, Biological; Mutation; Predictive Value of Tests; Pseudomonas aeruginosa; Pseudomonas Infections	2012
Predicting doripenem susceptibility based on meropenem and imipenem interpretation for Pseudomonas aeruginosa. Diagnostic microbiology and infectious disease, 2012, Volume: 72, Issue:3 Topics: Anti-Bacterial Agents; Carbapenems; Doripenem; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Prognosis; Pseudomonas aeruginosa; Pseudomonas Infections; Reference Standards; Thienamycins	2012
Comparative Activity of Carbapenem Testing (COMPACT) study in Germany. International journal of antimicrobial agents, 2012, Volume: 39, Issue:3 Topics: Bacteremia; Carbapenems; Cross Infection; Doripenem; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Germany; Humans; Imipenem; Intensive Care Units; Intraabdominal Infections; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Quality Control; Thienamycins	2012
Class A carbapenemase FPH-1 from Francisella philomiragia. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:6 Topics: Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Clavulanic Acid; Doripenem; Ertapenem; Escherichia coli; Francisella; Imipenem; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam; Tazobactam; Thienamycins	2012
Use of Carbapenems against clinical, nontyphoid Salmonella isolates: results from in vitro and in vivo animal studies. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:6 Topics: Animals; beta-Lactams; Carbapenems; Cell Line; Doripenem; Ertapenem; Female; Imipenem; Meropenem; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Peritonitis; Salmonella; Thienamycins	2012
OXA-162, a novel variant of OXA-48 displays extended hydrolytic activity towards imipenem, meropenem and doripenem. Journal of enzyme inhibition and medicinal chemistry, 2013, Volume: 28, Issue:5 Topics: beta-Lactamases; Biocatalysis; Carbapenems; Cloning, Molecular; DNA Transposable Elements; Doripenem; Drug Resistance, Bacterial; Humans; Hydrolysis; Imipenem; Klebsiella pneumoniae; Meropenem; Models, Molecular; Plasmids; Thienamycins	2013
Doripenem: excess mortality. Prescrire international, 2012, Volume: 21, Issue:130 Topics: Anti-Bacterial Agents; Carbapenems; Cilastatin; Cilastatin, Imipenem Drug Combination; Doripenem; Drug Combinations; Early Termination of Clinical Trials; Evidence-Based Medicine; Humans; Imipenem; Pneumonia, Ventilator-Associated; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Treatment Outcome	2012
Activities of doripenem against nosocomial bacteremic drug-resistant Gram-negative bacteria in a medical center in Taiwan. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2012, Volume: 45, Issue:6 Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacteremia; Carbapenems; Cross Infection; Doripenem; Drug Resistance, Bacterial; Enterobacteriaceae; Gram-Negative Bacteria; Hospitals, University; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Taiwan; Thienamycins	2012
Pharmacodynamic profiling of doripenem, imipenem and meropenem against prevalent Gram-negative organisms in the Asia-Pacific region. International journal of antimicrobial agents, 2013, Volume: 41, Issue:1 Topics: Anti-Bacterial Agents; Carbapenems; Doripenem; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Pacific Islands; Thienamycins; Time Factors	2013
[Comparison of ertapenem-EMB Agar with traditional methods for screening carbapenem-resistant Klebsiella pneumoniae from rectal swabs]. Mikrobiyoloji bulteni, 2012, Volume: 46, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Carbapenems; Culture Media; Doripenem; Drug Resistance, Bacterial; Ertapenem; Humans; Imipenem; Klebsiella Infections; Klebsiella pneumoniae; Meropenem; Multiplex Polymerase Chain Reaction; Rectum; Sensitivity and Specificity; Thienamycins; Time Factors	2012
Comparison of in vitro activity of doripenem, imipenem and meropenem against clinical isolates of Enterobacteriaceae, Pseudomonas and Acinetobacter in Southern Poland. Polski przeglad chirurgiczny, 2012, Volume: 84, Issue:9 Topics: Acinetobacter; Acinetobacter baumannii; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Carbapenems; Doripenem; Enterobacteriaceae; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Poland; Pseudomonas; Species Specificity; Sputum; Thienamycins	2012
Combined effects of the siderophore monosulfactam BAL30072 and carbapenems on multidrug-resistant Gram-negative bacilli. The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:5 Topics: Acinetobacter; Anti-Bacterial Agents; Carbapenems; Doripenem; Drug Resistance, Multiple, Bacterial; Drug Synergism; Enterobacteriaceae; Imipenem; Meropenem; Microbial Sensitivity Tests; Microbial Viability; Monobactams; Pseudomonas aeruginosa; Thiazoles; Thienamycins	2013
When pharmacodynamics trump costs: an antimicrobial stewardship program's approach to selecting optimal antimicrobial agents. Clinical therapeutics, 2013, Volume: 35, Issue:6 Topics: Adult; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Doripenem; Drug Costs; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Monte Carlo Method; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins	2013
In vitro sensitivity of Acinetobacter baumannii and Pseudomonas aeruginosa to carbapenems among intensive care unit patients. Advances in experimental medicine and biology, 2013, Volume: 788 Topics: Acinetobacter baumannii; Bacterial Infections; Carbapenems; Doripenem; Electrophoresis, Gel, Pulsed-Field; Europe; Humans; Imipenem; Intensive Care Units; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Sensitivity and Specificity; Species Specificity; Thienamycins; United States; United States Food and Drug Administration	2013
IMP-43 and IMP-44 metallo-β-lactamases with increased carbapenemase activities in multidrug-resistant Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:9 Topics: Amino Acid Substitution; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Catalytic Domain; Doripenem; Drug Resistance, Multiple, Bacterial; Escherichia coli; Humans; Hydrophobic and Hydrophilic Interactions; Imipenem; Japan; Meropenem; Phylogeny; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections; Structure-Activity Relationship; Thienamycins	2013
In vitro cross-linking of Mycobacterium tuberculosis peptidoglycan by L,D-transpeptidases and inactivation of these enzymes by carbapenems. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12 Topics: Antitubercular Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Carbapenems; Cell Wall; Clavulanic Acid; Doripenem; Enzyme Assays; Ertapenem; Escherichia coli; Gene Expression; Imipenem; Kinetics; Meropenem; Mycobacterium tuberculosis; Peptidoglycan; Peptidyl Transferases; Recombinant Proteins; Thienamycins	2013
[A comparison of susceptibility of Pseudomonas aeruginosa clinical isolates to carbapenem antibiotics in our hospital]. The Japanese journal of antibiotics, 2014, Volume: 67, Issue:4 Topics: Carbapenems; Doripenem; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins	2014
Interspecies scaling of excretory amounts using allometry - retrospective analysis with rifapentine, aztreonam, carumonam, pefloxacin, miloxacin, trovafloxacin, doripenem, imipenem, cefozopran, ceftazidime, linezolid for urinary excretion and rifapentine, Xenobiotica; the fate of foreign compounds in biological systems, 2016, Volume: 46, Issue:9 Topics: Animals; Anti-Bacterial Agents; Aztreonam; Carbapenems; Cefozopran; Ceftazidime; Cephalosporins; Doripenem; Feces; Fluoroquinolones; Heterocyclic Compounds, 3-Ring; Humans; Imipenem; Linezolid; Naphthyridines; Oxazines; Oxolinic Acid; Pefloxacin; Piperazines; Pyridones; Retrospective Studies; Rifampin	2016
MIC score, a new tool to compare bacterial susceptibility to antibiotics application to the comparison of susceptibility to different penems of clinical strains of Pseudomonas aeruginosa. The Journal of antibiotics, 2016, Volume: 69, Issue:11 Topics: Anti-Bacterial Agents; Carbapenems; Cystic Fibrosis; Doripenem; Drug Resistance, Multiple, Bacterial; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins	2016
Comparative In Vitro Efficacy of Doripenem and Imipenem Against Multi-Drug Resistant Pseudomonas aeruginosa. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2016, Volume: 26, Issue:4 Topics: Anti-Bacterial Agents; Carbapenems; Cross-Sectional Studies; Doripenem; Drug Resistance, Multiple; Humans; Imipenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections	2016
Structural Insights into Recognition of Hydrolyzed Carbapenems and Inhibitors by Subclass B3 Metallo-β-Lactamase SMB-1. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:7 Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents; beta-Lactamases; Captopril; Carbapenems; Catalytic Domain; Crystallography, X-Ray; Doripenem; Imipenem; Meropenem; Mesna; Protein Structure, Secondary; Protein Structure, Tertiary; Serratia marcescens; Thienamycins	2016
Comparative in vitro activity of carbapenems against clinical isolates of Acinetobacter baumannii. Journal of applied microbiology, 2016, Volume: 121, Issue:2 Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Cross Infection; Doripenem; Humans; Imipenem; Iran; Meropenem; Microbial Sensitivity Tests; Thienamycins	2016
Pharmacodynamics of carbapenems for the treatment of Pseudomonas aeruginosa ventilator-associated pneumonia: associations with clinical outcome and recurrence. The Journal of antimicrobial chemotherapy, 2016, Volume: 71, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Animals; Anti-Bacterial Agents; Carbapenems; Disk Diffusion Antimicrobial Tests; Doripenem; Female; Humans; Imipenem; Male; Meropenem; Middle Aged; Pneumonia, Ventilator-Associated; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Recurrence; Thienamycins; Treatment Outcome	2016
In vitro antibacterial activity of rifampicin in combination with imipenem, meropenem and doripenem against multidrug-resistant clinical isolates of Pseudomonas aeruginosa. BMC infectious diseases, 2016, 08-24, Volume: 16, Issue:1 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Colistin; Doripenem; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Porins; Pseudomonas aeruginosa; Pseudomonas Infections; Rifampin; Taiwan; Thienamycins	2016
Carbapenem MICs in Escherichia coli and Klebsiella Species Producing Extended-Spectrum β-Lactamases in Critical Care Patients from 2001 to 2009. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:4 Topics: Adult; Aged; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Carbapenems; Critical Care; Doripenem; Ertapenem; Escherichia coli; Escherichia coli Infections; Female; Gene Expression; Genotype; Humans; Imipenem; Klebsiella; Klebsiella Infections; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Multilocus Sequence Typing; Thienamycins; United States	2017
Multiple substitutions lead to increased loop flexibility and expanded specificity in The Biochemical journal, 2018, 01-11, Volume: 475, Issue:1 Topics: Acinetobacter baumannii; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; beta-Lactamases; Carbapenems; Catalytic Domain; Cefotaxime; Cloning, Molecular; Crystallography, X-Ray; Doripenem; Escherichia coli; Gene Expression; Genetic Vectors; Imipenem; Kinetics; Models, Molecular; Mutation; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity	2018
Interpreting carbapenem susceptibility testing results for Pseudomonas aeruginosa. Medecine et maladies infectieuses, 2018, Volume: 48, Issue:5 Topics: beta-Lactam Resistance; Carbapenems; Disk Diffusion Antimicrobial Tests; Doripenem; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Pneumonia, Ventilator-Associated; Practice Guidelines as Topic; Pseudomonas aeruginosa; Pseudomonas Infections; Reagent Strips; Sensitivity and Specificity	2018
Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D β-Lactamases. Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:2 Topics: Acinetobacter baumannii; Amino Acid Substitution; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Doripenem; Drug Resistance, Bacterial; Imipenem; Meropenem; Microbial Sensitivity Tests; Protein Conformation	2019
lptG contributes to changes in membrane permeability and the emergence of multidrug hypersusceptibility in a cystic fibrosis isolate of Pseudomonas aeruginosa. MicrobiologyOpen, 2019, Volume: 8, Issue:11 Topics: Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Cell Membrane; Codon, Nonsense; Cystic Fibrosis; Doripenem; Drug Resistance, Bacterial; Electrophoresis, Polyacrylamide Gel; Humans; Imipenem; Lipopolysaccharides; Meropenem; Microbial Sensitivity Tests; Mutation, Missense; Permeability; Porins; Pseudomonas aeruginosa; Pseudomonas Infections; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Whole Genome Sequencing	2019
Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 β-Lactamase. Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:10 Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Catalytic Domain; Doripenem; Hydrophobic and Hydrophilic Interactions; Imipenem; Meropenem; Microbial Sensitivity Tests; Protein Structure, Secondary	2019
In vitro and in vivo assessment of the antibacterial activity of colistin alone and in combination with other antibiotics against Acinetobacter baumannii and Escherichia coli. Journal of global antimicrobial resistance, 2020, Volume: 20 Topics: Acinetobacter baumannii; Administration, Intravenous; Animals; Anti-Bacterial Agents; Biofilms; Colistin; Disease Models, Animal; Doripenem; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Escherichia coli; Escherichia coli Infections; Female; Humans; Imipenem; Meropenem; Mice; Microbial Sensitivity Tests; Monte Carlo Method; Sulbactam; Treatment Outcome; Urinary Tract Infections	2020
Antimicrobial susceptibility and prevalence of resistance genes in Bacteroides fragilis isolated from blood culture bottles in two tertiary care hospitals in Japan. Anaerobe, 2020, Volume: 64 Topics: Ampicillin; Anti-Bacterial Agents; Bacterial Proteins; Bacteroides fragilis; Bacteroides Infections; beta-Lactamases; Blood Culture; DNA Transposable Elements; Doripenem; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Humans; Imipenem; Japan; Meropenem; Metronidazole; Microbial Sensitivity Tests; Moxifloxacin; Piperacillin, Tazobactam Drug Combination; Prevalence; Sulbactam; Tertiary Care Centers	2020
A method to quantify viable carbapenem resistant gram-negative bacteria in treated and untreated wastewater. Journal of microbiological methods, 2020, Volume: 179 Topics: Anti-Bacterial Agents; Bacterial Load; Bacterial Proteins; beta-Lactamases; Carbapenem-Resistant Enterobacteriaceae; Carbapenems; Disk Diffusion Antimicrobial Tests; Doripenem; Ertapenem; Imipenem; Meropenem; Wastewater; Water Purification	2020
Improving Traditional Registrational Trial End Points: Development and Application of a Desirability of Outcome Ranking End Point for Complicated Urinary Tract Infection Clinical Trials. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 02-08, Volume: 76, Issue:3 Topics: Anti-Bacterial Agents; Doripenem; Humans; Imipenem; Levofloxacin; Urinary Tract Infections	2023
Carbapenem resistance gene crisis in A. baumannii: a computational analysis. BMC microbiology, 2022, 12-03, Volume: 22, Issue:1 Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Carbapenems; Doripenem; Imipenem; Meropenem; Molecular Docking Simulation	2022
Molecular docking and dynamic approach to screen the drug candidate against the Imipenem-resistant CarO porin in Acinetobacter baumannii. Microbial pathogenesis, 2023, Volume: 177 Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Carbapenems; Doripenem; Ertapenem; Imipenem; Meropenem; Microbial Sensitivity Tests; Molecular Docking Simulation; Porins	2023
In vitro activities of ceftazidime-avibactam, ceftolozane-tazobactam, meropenem-vaborbactam and other comparators against Pseudomonas aeruginosa isolates with discrepant resistance to carbapenems: Data from the Antimicrobial Testing Leadership and Surveil International journal of antimicrobial agents, 2023, Volume: 62, Issue:2 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azabicyclo Compounds; beta-Lactamases; Carbapenems; Ceftazidime; Cephalosporins; Doripenem; Humans; Imipenem; Leadership; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2023