Compounds > dopachrome
Page last updated: 2024-09-03

dopachrome and 5,6-dihydroxy-2-indolylcarboxylic acid

dopachrome has been researched along with 5,6-dihydroxy-2-indolylcarboxylic acid in 16 studies

Compound Research Comparison

Studies
(dopachrome)		Trials
(dopachrome)		Recent Studies (post-2010)
(dopachrome)		Studies
(5,6-dihydroxy-2-indolylcarboxylic acid)		Trials
(5,6-dihydroxy-2-indolylcarboxylic acid)		Recent Studies (post-2010) (5,6-dihydroxy-2-indolylcarboxylic acid)
9501599020

Protein Interaction Comparison

ProteinTaxonomydopachrome (IC50)5,6-dihydroxy-2-indolylcarboxylic acid (IC50)
Integrase Human immunodeficiency virus 110

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's10 (62.50)18.2507
2000's0 (0.00)29.6817
2010's4 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aroca, P; García-Borrón, JC; Lozano, JA; Solano, F1
Pawelek, JM1
King, RA; Leonard, LJ; Townsend, D1
Gettins, P; Korner, AM1
Mishima, Y; Wilczek, A2
Brewington, T; Hearing, VJ; Imokawa, G; Kobayashi, T; Potterf, B; Tsukamoto, K; Urabe, K; Winder, A1
Odh, G; Rorsman, H; Rosengren, E; Winder, AJ; Wittbjer, A1
Aman, P; Bucala, R; Jacobsson, L; Metz, CN; Odh, G; Rorsman, H; Rosengren, E1
Ahlfors, S; Aman, P; Björk, P; Hansson, C; Jacobsson, L; Rorsman, H; Rosengren, E; Thelin, S1
Fujinaga, M; Kuriyama, T; Nakagawa, A; Nishihira, J; Sakai, M; Sugimoto, H; Suzuki, M; Tanaka, I1
Rorsman, H; Rosengren, E1
Commo, S; Ito, S; Suzuki, N; Takebayashi, S; Wakamatsu, K1
Kasai, H; Kishida, R; Saputro, AG; Ushijima, Y1
Kasai, H; Kishida, R; Saputro, AG1
Beberok, A; Buszman, E; Rzepka, Z; Wrześniok, D1

Reviews

2 review(s) available for dopachrome and 5,6-dihydroxy-2-indolylcarboxylic acid

ArticleYear
After dopachrome?
    Pigment cell research, 1991, Volume: 4, Issue:2

    Topics: Animals; Cell Fractionation; Enzyme Activation; Indolequinones; Indoles; Isomerases; Melanins; Melanocytes; Melanoma; Pigmentation; Quinones; Tumor Cells, Cultured

1991
From tyrosine to melanin: Signaling pathways and factors regulating melanogenesis.
    Postepy higieny i medycyny doswiadczalnej (Online), 2016, Jun-30, Volume: 70, Issue:0

    Topics: Animals; Benzoquinones; Cytokines; Dihydroxyphenylalanine; Gene Expression Regulation, Enzymologic; Hormones; Humans; Indolequinones; Indoles; Melanins; Melanosomes; Monophenol Monooxygenase; Signal Transduction; Tyrosine; Ultraviolet Rays

2016

Other Studies

14 other study(ies) available for dopachrome and 5,6-dihydroxy-2-indolylcarboxylic acid

ArticleYear
After dopachrome.
    Pigment cell research, 1991, Volume: 4, Issue:5-6

    Topics: Indolequinones; Indoles; Intramolecular Oxidoreductases; Isomerases; Quinones

1991
Function of dopachrome oxidoreductase and metal ions in dopachrome conversion in the eumelanin pathway.
    Biochemistry, 1988, Aug-09, Volume: 27, Issue:16

    Topics: Animals; Catechol Oxidase; Hot Temperature; In Vitro Techniques; Indolequinones; Indoles; Intramolecular Oxidoreductases; Melanins; Melanocytes; Melanoma, Experimental; Metals; Mice; Quinones

1988
Synthesis in vitro of 5,6-dihydroxyindole-2-carboxylic acid by dopachrome conversion factor from Cloudman S91 melanoma cells.
    The Journal of investigative dermatology, 1985, Volume: 85, Issue:3

    Topics: Animals; Carbon Isotopes; Cell Line; Indolequinones; Indoles; Magnetic Resonance Spectroscopy; Melanoma; Mice; Quinones

1985
Inhibitory effects of melanin monomers, dihydroxyindole-2-carboxylic acid (DHICA) and dihydroxyindole (DHI) on mammalian tyrosinase, with a special reference to the role of DHICA/DHI ratio in melanogenesis.
    Pigment cell research, 1995, Volume: 8, Issue:2

    Topics: Animals; Cricetinae; Fibroblasts; Humans; Indolequinones; Indoles; Intramolecular Oxidoreductases; Isomerases; Kinetics; Melanins; Monophenol Monooxygenase; Quinones; Transfection; Tyrosine

1995
DHICA oxidase activity of TRP1 and interactions with other melanogenic enzymes.
    Pigment cell research, 1994, Volume: 7, Issue:4

    Topics: Animals; Catalysis; Enzyme Stability; Fibroblasts; Indolequinones; Indoles; Melanins; Melanoma, Experimental; Membrane Glycoproteins; Mice; Monophenol Monooxygenase; Oxidoreductases; Pigmentation; Proteins; Quinones; Transfection

1994
The mouse brown (b) locus protein functions as a dopachrome tautomerase.
    Pigment cell research, 1994, Volume: 7, Issue:5

    Topics: 3T3 Cells; Animals; Blotting, Western; Catalase; Fluorescent Antibody Technique; Glycoproteins; Indolequinones; Indoles; Intramolecular Oxidoreductases; Isomerases; Melanins; Membrane Glycoproteins; Mice; Monophenol Monooxygenase; Oxidoreductases; Quinones; Transfection

1994
Regulatory factors for polymerization of melanin monomers within coated vesicles and premelanosomes in melanoma cells.
    Melanoma research, 1993, Volume: 3, Issue:4

    Topics: Animals; Chromatography, Affinity; Chromatography, High Pressure Liquid; Coated Pits, Cell-Membrane; Cricetinae; Indolequinones; Indoles; Kinetics; Melanins; Melanocytes; Melanoma, Amelanotic; Melanoma, Experimental; Mesocricetus; Monophenol Monooxygenase; Organelles; Quinones

1993
The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction.
    Molecular medicine (Cambridge, Mass.), 1996, Volume: 2, Issue:1

    Topics: Amino Acid Sequence; Animals; Cattle; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Indolequinones; Indoles; Lens, Crystalline; Macrophage Migration-Inhibitory Factors; Molecular Sequence Data; Molecular Structure; Quinones; Recombinant Proteins; Sequence Alignment; Sequence Analysis

1996
The macrophage migration inhibitory factor MIF is a phenylpyruvate tautomerase.
    FEBS letters, 1997, Nov-03, Volume: 417, Issue:1

    Topics: Amino Acids; Animals; Cattle; Humans; Indolequinones; Indoles; Intramolecular Oxidoreductases; Macrophage Migration-Inhibitory Factors; Phenylpyruvic Acids; Quinones; Recombinant Fusion Proteins; Substrate Specificity

1997
Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation.
    Biochemical and biophysical research communications, 1998, Feb-13, Volume: 243, Issue:2

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Enzyme Activation; Gene Expression Regulation; Humans; Indolequinones; Indoles; Intramolecular Oxidoreductases; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Quinones; Rats; RNA, Messenger; Sequence Alignment; Sequence Analysis, DNA

1998
Reducing compounds initiate the TRP2-catalyzed conversion of L-dopachrome to DHICA.
    Melanoma research, 1998, Volume: 8, Issue:5

    Topics: Acetylcysteine; Animals; Cysteine; Indolequinones; Indoles; Intramolecular Oxidoreductases; Melanoma, Experimental; Mice; Oxidation-Reduction; Quinones; Rabbits; Reducing Agents

1998
Neutral pH and copper ions promote eumelanogenesis after the dopachrome stage.
    Pigment cell & melanoma research, 2013, Volume: 26, Issue:6

    Topics: Biosynthetic Pathways; Copper; Humans; Hydrogen-Ion Concentration; Indolequinones; Indoles; Ions; Kinetics; Melanins

2013
Effect of pH on elementary steps of dopachrome conversion from first-principles calculation.
    Pigment cell & melanoma research, 2014, Volume: 27, Issue:5

    Topics: Humans; Hydrogen; Hydrogen-Ion Concentration; Indolequinones; Indoles; Intramolecular Oxidoreductases; Kinetics; Models, Chemical; Pigmentation; Protons; Software; Solvents

2014
Mechanism of dopachrome tautomerization into 5,6-dihydroxyindole-2-carboxylic acid catalyzed by Cu(II) based on quantum chemical calculations.
    Biochimica et biophysica acta, 2015, Volume: 1850, Issue:2

    Topics: Catalysis; Copper; Indolequinones; Indoles; Models, Chemical; Quantum Theory

2015