donitriptan has been researched along with sumatriptan in 4 studies
| Studies (donitriptan) | Trials (donitriptan) | Recent Studies (post-2010) (donitriptan) | Studies (sumatriptan) | Trials (sumatriptan) | Recent Studies (post-2010) (sumatriptan) |
|---|---|---|---|---|---|
| 13 | 0 | 4 | 2,405 | 461 | 480 |
| Protein | Taxonomy | donitriptan (IC50) | sumatriptan (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 3E | Homo sapiens (human) | 0.0073 | |
| 5-hydroxytryptamine receptor 3B | Homo sapiens (human) | 0.0073 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.4497 | |
| Carboxypeptidase M | Homo sapiens (human) | 0.02 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.64 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.722 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.64 | |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | 0.3091 | |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | 0.0131 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 7.9433 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 3.9753 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.804 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 0.061 | |
| 5-hydroxytryptamine receptor 1E | Homo sapiens (human) | 5.5 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.64 | |
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | 0.0078 | |
| 5-hydroxytryptamine receptor 5A | Homo sapiens (human) | 0.5012 | |
| 5-hydroxytryptamine receptor 1D | Sus scrofa (pig) | 0.02 | |
| 5-hydroxytryptamine receptor 1A | Mus musculus (house mouse) | 0.45 | |
| 5-hydroxytryptamine receptor 3D | Homo sapiens (human) | 0.0073 | |
| 5-hydroxytryptamine receptor 3C | Homo sapiens (human) | 0.0073 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 6.7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diener, HC; Guehring, H; Katsarava, Z; Liedert, B; Limmroth, V; Michel, MC; Schmitz, K | 1 |
| Avezaat, CJ; Bogers, AJ; John, GW; MaassenVanDenBrink, A; Mulder, PG; Saxena, PR; van den Broek, RW | 1 |
| Blanchet, JC; John, GW; Le Grand, B; Létienne, R; Sole, E | 1 |
| Centurión, D; Gupta, S; Jiménez-Mena, LR; Lozano-Cuenca, J; MaassenVanDenBrink, A; Mehrotra, S; Muñoz-Islas, E; Sánchez-López, A; Villalón, CM | 1 |
4 other study(ies) available for donitriptan and sumatriptan
| Article | Year |
|---|---|
An in vivo rat model to study calcitonin gene related peptide release following activation of the trigeminal vascular system.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcitonin Gene-Related Peptide; Disease Models, Animal; Male; Meninges; Migraine Disorders; Nerve Fibers; Neuralgia; Nitriles; Piperazines; Rats; Rats, Sprague-Dawley; Sumatriptan; Trigeminal Ganglion; Tryptamines; Vasoconstrictor Agents | 2001 |
Comparison of contractile responses to donitriptan and sumatriptan in the human middle meningeal and coronary arteries.
Topics: Adult; Aged; Coronary Vessels; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Meningeal Arteries; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Nitriles; Piperazines; Predictive Value of Tests; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Substance P; Sumatriptan; Tryptamines; Vasoconstrictor Agents | 2002 |
Donitriptan decreases jugular venous oxygen saturation in rats in the absence of cranial vasoconstriction: an overlooked mechanism of antimigraine action?
Topics: Animals; Blood Gas Analysis; Cerebrovascular Circulation; Hemodynamics; Jugular Veins; Male; Migraine Disorders; Nitriles; Oxadiazoles; Oxygen; Piperazines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstriction | 2005 |
Donitriptan, but not sumatriptan, inhibits capsaicin-induced canine external carotid vasodilatation via 5-HT1B rather than 5-HT1D receptors.
Topics: Acetylcholine; Animals; Benzopyrans; Calcitonin Gene-Related Peptide; Capsaicin; Carotid Artery, External; Chromans; Dogs; Dose-Response Relationship, Drug; Hemodynamics; Humans; In Vitro Techniques; Infusions, Intravenous; Nitriles; Phenylephrine; Piperazines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstrictor Agents; Vasodilation | 2006 |