donepezil hydrochloride has been researched along with tacrine in 5 studies
*Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. [MeSH]
*Tacrine: A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iimura, Y; Sugimoto, H; Yamanishi, Y; Yamatsu, K | 1 |
| Agnusdei, M; Belinskaya, T; Borriello, M; Brindisi, M; Butini, S; Campiani, G; Catalanotti, B; Fattorusso, C; Fiorini, I; Gemma, S; Nacci, V; Novellino, E; Panico, A; Persico, M; Ros, S; Saxena, A | 1 |
| Andrisano, V; Badia, A; Bartolini, M; Bidon-Chanal, A; Camins, A; Camps, P; Clos, MV; Estelrich, J; Formosa, X; Galdeano, C; Gómez, T; Lizondo, M; Luque, FJ; Mancini, F; Muñoz-Torrero, D; Pallàs, M; Scarpellini, M; Viayna, E | 1 |
| Mohamed, T; Rao, PP; Yeung, JC | 1 |
| Brazzolotto, X; Brus, B; Colletier, JP; Coquelle, N; Gobec, S; Knez, D; Kos, J; Košak, U; Nachon, F; Pišlar, A | 1 |
5 other study(ies) available for donepezil hydrochloride and tacrine
| Article | Year |
|---|---|
Synthesis and structure-activity relationships of acetylcholinesterase inhibitors: 1-benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine hydrochloride and related compounds.
Topics: Animals; Binding Sites; Brain; Cholinesterase Inhibitors; Donepezil; Indans; Male; Mice; Piperidines; Rats; Rats, Wistar; Structure-Activity Relationship | 1995 |
Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors.
Topics: Acetylcholinesterase; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Computational Biology; Crystallography, X-Ray; Drug Design; Humans; Models, Molecular; Protein Conformation; Structure-Activity Relationship; Tacrine | 2008 |
Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Animals; Binding Sites; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Donepezil; Humans; Indans; Models, Molecular; Piperidines; Structure-Activity Relationship; Tacrine | 2008 |
Development of 2-substituted-N-(naphth-1-ylmethyl) and N-benzhydrylpyrimidin-4-amines as dual cholinesterase and Aβ-aggregation inhibitors: Synthesis and biological evaluation.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzhydryl Compounds; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Humans; Models, Molecular; Molecular Structure; Molecular Targeted Therapy; Parkinson Disease; Plaque, Amyloid; Pyrimidines; Structure-Activity Relationship | 2011 |
N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Butyrylcholinesterase; Cell Death; Cell Line; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Naphthalenes; Peptide Fragments; Piperidines; Structure-Activity Relationship; Sulfonamides | 2017 |