donepezil and sertraline

donepezil has been researched along with sertraline in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (40.00)29.6817
2010's9 (45.00)24.3611
2020's3 (15.00)2.80

Authors

AuthorsStudies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Qin, W; Tian, S; Wold, EA; Xu, Q; Ye, N; Zhen, XC; Zhou, J1
Nace, DA; Towers, AL; Verrico, MM1
Burt, T; Dysken, M; Finkel, SI; Krishnan, KR; McRae, T; Mintzer, JE1
Cullen, EI; Kumar, D; Nagy, CF; Perdomo, CA; Pratt, RD; Wason, S1
Berger, P; Bloch, DA; Coleman, FS; Elkashef, A; Goldsmith, RJ; Harrer, JM; Leiderman, DB; Mezinskis, JP; Montgomery, MA; Singal, BM; Somoza, EC; Winhusen, TM1
Cummings, JL; McRae, T; Zhang, R1
Devanand, DP; Harper, OL; Pelton, GH; Roose, SP; Sackeim, HA; Scarmeas, N; Tabert, MH1
Abernethy, AP; Farrell, TW1
Mori, N; Suda, S; Sugihara, G; Suyama, R; Takei, N1
Krishnamurthy, S; Prajapati, SK1
Finn, DP; Joshi, A; McClean, PL; Todd, S; Wong-Lin, K1

Reviews

3 review(s) available for donepezil and sertraline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases.
    Journal of medicinal chemistry, 2020, 12-24, Volume: 63, Issue:24

    Topics: Allosteric Regulation; Clinical Trials as Topic; Humans; Ligands; Nervous System Diseases; Piperidines; Receptors, sigma; Sigma-1 Receptor; Small Molecule Libraries

2020
Pain and palliative care pharmacotherapy literature summaries and analyses.
    Journal of pain & palliative care pharmacotherapy, 2009, Volume: 23, Issue:1

    Topics: Alzheimer Disease; Amphetamines; Anesthetics, Local; Anticoagulants; Antidepressive Agents; Depression; Donepezil; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Humans; Indans; Lidocaine; Nootropic Agents; Pain; Palliative Care; Phlebotomy; Piperidines; Prescription Drugs; Psychomotor Agitation; Randomized Controlled Trials as Topic; Sertraline; Stevens-Johnson Syndrome; Thromboembolism

2009

Trials

5 trial(s) available for donepezil and sertraline

ArticleYear
A randomized, placebo-controlled study of the efficacy and safety of sertraline in the treatment of the behavioral manifestations of Alzheimer's disease in outpatients treated with donepezil.
    International journal of geriatric psychiatry, 2004, Volume: 19, Issue:1

    Topics: Aged; Alzheimer Disease; Ambulatory Care; Antidepressive Agents; Behavioral Symptoms; Cholinesterase Inhibitors; Donepezil; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Indans; Male; Middle Aged; Neuropsychological Tests; Nootropic Agents; Piperidines; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome

2004
Concurrent administration of donepezil HCl and sertraline HCl in healthy volunteers: assessment of pharmacokinetic changes and safety following single and multiple oral doses.
    British journal of clinical pharmacology, 2004, Volume: 58 Suppl 1

    Topics: Administration, Oral; Adult; Antidepressive Agents; Cholinesterase Inhibitors; Cross-Over Studies; Donepezil; Drug Combinations; Drug Interactions; Female; Half-Life; Humans; Indans; Male; Middle Aged; Piperidines; Selective Serotonin Reuptake Inhibitors; Sertraline

2004
A placebo-controlled screening trial of tiagabine, sertraline and donepezil as cocaine dependence treatments.
    Addiction (Abingdon, England), 2005, Volume: 100 Suppl 1

    Topics: Adult; Anticonvulsants; Cocaine-Related Disorders; Donepezil; Female; Humans; Indans; Male; Middle Aged; Nipecotic Acids; Piperidines; Selective Serotonin Reuptake Inhibitors; Sertraline; Tiagabine

2005
Effects of donepezil on neuropsychiatric symptoms in patients with dementia and severe behavioral disorders.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2006, Volume: 14, Issue:7

    Topics: Aged; Cholinesterase Inhibitors; Dementia; Demography; Donepezil; Double-Blind Method; Factor Analysis, Statistical; Female; Humans; Indans; Male; Mental Disorders; Middle Aged; Piperidines; Prevalence; Sertraline; Severity of Illness Index; Treatment Outcome

2006
Randomized double-blind placebo-controlled donepezil augmentation in antidepressant-treated elderly patients with depression and cognitive impairment: a pilot study.
    International journal of geriatric psychiatry, 2008, Volume: 23, Issue:7

    Topics: Aged; Antidepressive Agents; Cholinesterase Inhibitors; Cognition Disorders; Depressive Disorder; Donepezil; Epidemiologic Methods; Female; Humans; Indans; Male; Middle Aged; Neuropsychological Tests; Nootropic Agents; Piperidines; Sertraline; Treatment Outcome

2008

Other Studies

12 other study(ies) available for donepezil and sertraline

ArticleYear
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Fulminant chemical hepatitis possibly associated with donepezil and sertraline therapy.
    Journal of the American Geriatrics Society, 2000, Volume: 48, Issue:12

    Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Alzheimer Disease; Bilirubin; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Donepezil; Drug Monitoring; Drug Therapy, Combination; Female; gamma-Glutamyltransferase; Humans; Indans; Liver Failure, Acute; Liver Function Tests; Nootropic Agents; Piperidines; Selective Serotonin Reuptake Inhibitors; Sertraline; Tomography, X-Ray Computed

2000
Donepezil and concurrent sertraline treatment is associated with increased hippocampal volume in a patient with depression.
    The Journal of clinical psychiatry, 2010, Volume: 71, Issue:6

    Topics: Adult; Alzheimer Disease; Atrophy; Cholinesterase Inhibitors; Cognition Disorders; Depressive Disorder, Major; Diagnosis, Differential; Donepezil; Drug Therapy, Combination; Female; Follow-Up Studies; Functional Laterality; Hippocampus; Humans; Indans; Magnetic Resonance Imaging; Piperidines; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome

2010
Development and treatment of cognitive inflexibility in sub-chronic stress-re-stress (SRS) model of PTSD.
    Pharmacological reports : PR, 2021, Volume: 73, Issue:2

    Topics: Acetylcholine; Animals; Cholinesterase Inhibitors; Cognition Disorders; Disease Models, Animal; Donepezil; Hippocampus; Male; Prefrontal Cortex; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Sertraline; Stress Disorders, Post-Traumatic

2021
Multi-dimensional relationships among dementia, depression and prescribed drugs in England and Wales hospitals.
    BMC medical informatics and decision making, 2022, 10-07, Volume: 22, Issue:1

    Topics: Aged; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Depression; Donepezil; Dothiepin; Frontotemporal Dementia; Hospitals; Humans; Lamotrigine; Memantine; Mirtazapine; NAD; Sertraline; Valproic Acid; Venlafaxine Hydrochloride; Wales

2022