donepezil has been researched along with roflumilast in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| An, B; Hu, J; Huang, L; Li, X; Li, Z; Pan, T | 1 |
| Chen, Z; Gao, Y; Guo, L; He, X; Huang, L; Huang, YY; Li, Z; Liang, J; Liang, SH; Luo, HB; Wu, D; Wu, R; Yu, S; Zhou, Q | 1 |
| Akkerman, S; Blokland, A; Creemers, P; De Vry, J; Prickaerts, J; Sambeth, A; Uz, T; van Duinen, M; Vanmierlo, T | 1 |
3 other study(ies) available for donepezil and roflumilast
| Article | Year |
|---|---|
Synthesis and evaluation of clioquinol-rolipram/roflumilast hybrids as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Aminopyridines; Animals; Benzamides; Clioquinol; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Drug Design; Humans; Ligands; Mice; Rats; Rolipram | 2019 |
Discovery and Optimization of α-Mangostin Derivatives as Novel PDE4 Inhibitors for the Treatment of Vascular Dementia.
Topics: Aminopyridines; Animals; Benzamides; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Dementia, Vascular; Dogs; Drug Design; Humans; Male; Mice, Inbred C57BL; Molecular Structure; Phosphodiesterase 4 Inhibitors; Protein Binding; Rolipram; Structure-Activity Relationship; Vomiting; Xanthones | 2020 |
The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses.
Topics: Aminopyridines; Animals; Benzamides; Cyclopropanes; Donepezil; Indans; Male; Memory; Mice; Mice, Inbred C57BL; Nootropic Agents; Phosphodiesterase 4 Inhibitors; Piperidines; Rats, Wistar; Recognition, Psychology; Rolipram; Scopolamine; Spatial Memory; Vomiting | 2016 |