donepezil and quercetin

donepezil has been researched along with quercetin in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's11 (84.62)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Ismaïli, L; Iutzeler, A; Luzet, V; Pudlo, M; Refouvelet, B; Tomassoli, I1
Alipour, M; Emami, S; Foroumadi, A; Hasanpour, Z; Homayouni Moghadam, F; Khoobi, M; Moradi, A; Nadri, H; Shafiee, A1
Huang, L; Li, W; Li, X; Wang, B; Wang, Y; Wang, Z1
Asadipour, A; Bukhari, SNA; Emami, S; Firoozpour, L; Foroumadi, A; Golshani, M; Homayouni Moghadam, F; Jafari, M; Jalili-Baleh, L; Khoobi, M; Moradi, A; Nadri, H; Shakibaie, M1
Andrisano, V; Apperley, KYP; Bartolini, M; Baschieri, A; Basso, M; Chen, HH; De Simone, A; Guardigni, M; Keillor, JW; Kobrlova, T; Milelli, A; Montanari, S; Soukup, O; Valgimigli, L1
Abbas Bukhari, SN; Abdolahi, Z; Abdollahi, M; Ameri, A; Ayazgok, B; Baeeri, M; Emami, S; Forootanfar, H; Foroumadi, A; Ganjali, MR; Jafari, M; Jalili-Baleh, L; Khoobi, M; Küçükkılınç, TT; Nadri, H; Rahimifard, M1
Barazandeh Tehrani, M; Hosseini, F; Larijani, B; Mahdavi, M; Mohammadi-Khanaposhtani, M; Nadri, H; Ramazani, A1
Han, J; Ji, L; Li, Z; Ma, J; Wang, M; Wu, M1
Altomare, CD; Carrieri, A; Catto, M; de Candia, M; De Palma, A; Ivanova, OA; Pisani, L; Purgatorio, R; Toma, M; Voskressensky, LG1
Bergamini, C; Bolognesi, ML; Claeysen, S; Dallemagne, P; Davis, A; Hatat, B; Lanthier, C; Lecoutey, C; Liparulo, I; Payan, H; Rochais, C; Since, M1
Andrisano, V; Arce, EM; Barenys, M; Bartolini, M; Bolognesi, ML; Brea, J; De Simone, A; Decker, M; Ginex, T; Gómez-Catalán, J; Griñán-Ferré, C; Loza, MI; Luque, FJ; Martínez, N; Mattellone, A; Muñoz-Torrero, D; Naldi, M; Pallàs, M; Pérez, B; Pont, C; Sabate, R; Scheiner, M; Soriano-Fernández, Y1
Chen, S; Du, J; Li, R; Li, Z; Liu, T; Xing, S1

Other Studies

13 other study(ies) available for donepezil and quercetin

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Quinolone-benzylpiperidine derivatives as novel acetylcholinesterase inhibitor and antioxidant hybrids for Alzheimer disease.
    Bioorganic & medicinal chemistry, 2014, Apr-15, Volume: 22, Issue:8

    Topics: Acetylcholinesterase; Alzheimer Disease; Antioxidants; Binding Sites; Catalytic Domain; Cholinesterase Inhibitors; Humans; Molecular Docking Simulation; Piperidines; Quinolones; Structure-Activity Relationship

2014
Synthesis and anti-cholinesterase activity of new 7-hydroxycoumarin derivatives.
    European journal of medicinal chemistry, 2014, Jul-23, Volume: 82

    Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cell Death; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophorus; Horses; Hydrogen Peroxide; Models, Molecular; Molecular Structure; PC12 Cells; Rats; Structure-Activity Relationship; Umbelliferones

2014
Design, Synthesis, and Evaluation of Orally Available Clioquinol-Moracin M Hybrids as Multitarget-Directed Ligands for Cognitive Improvement in a Rat Model of Neurodegeneration in Alzheimer's Disease.
    Journal of medicinal chemistry, 2015, Nov-12, Volume: 58, Issue:21

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Benzofurans; Clioquinol; Cognition; Cyclic Nucleotide Phosphodiesterases, Type 4; Inflammation; Ligands; Male; Memory; Models, Molecular; Neurons; Neuroprotective Agents; Phosphodiesterase 4 Inhibitors; Protein Aggregates; Rats; Rats, Wistar; Resorcinols

2015
New racemic annulated pyrazolo[1,2-b]phthalazines as tacrine-like AChE inhibitors with potential use in Alzheimer's disease.
    European journal of medicinal chemistry, 2017, Oct-20, Volume: 139

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Cell Death; Cell Proliferation; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Hydrogen Peroxide; Molecular Structure; Neuroprotective Agents; PC12 Cells; Phthalazines; Protein Aggregates; Pyrazoles; Rats; Structure-Activity Relationship

2017
Hydroxy-substituted trans-cinnamoyl derivatives as multifunctional tools in the context of Alzheimer's disease.
    European journal of medicinal chemistry, 2017, Oct-20, Volume: 139

    Topics: Alzheimer Disease; Animals; Cinnamates; Dose-Response Relationship, Drug; Free Radical Scavengers; Glycogen Synthase Kinase 3 beta; Molecular Structure; Stereoisomerism; Structure-Activity Relationship

2017
Design, synthesis and evaluation of novel multi-target-directed ligands for treatment of Alzheimer's disease based on coumarin and lipoic acid scaffolds.
    European journal of medicinal chemistry, 2018, May-25, Volume: 152

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Cholinesterase Inhibitors; Cholinesterases; Coumarins; Dose-Response Relationship, Drug; Drug Design; Humans; Hydrogen Peroxide; Ligands; Molecular Docking Simulation; Molecular Structure; PC12 Cells; Protein Aggregates; Rats; Reactive Oxygen Species; Structure-Activity Relationship; Thioctic Acid

2018
Design, synthesis, and biological evaluation of novel 4-oxobenzo[d]1,2,3-triazin-benzylpyridinum derivatives as potent anti-Alzheimer agents.
    Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13

    Topics: Alzheimer Disease; Humans; Neuroprotective Agents; Pyridines

2019
Design, synthesis, and biological evaluation of rutacecarpine derivatives as multitarget-directed ligands for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2019, Sep-01, Volume: 177

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Cell Line, Tumor; Chelating Agents; Cholinesterase Inhibitors; Drug Design; Humans; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protective Agents; Protein Multimerization; Rats; Structure-Activity Relationship; Sulfonamides

2019
Investigating 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole as scaffold of butyrylcholinesterase-selective inhibitors with additional neuroprotective activities for Alzheimer's disease.
    European journal of medicinal chemistry, 2019, Sep-01, Volume: 177

    Topics: Amyloid beta-Peptides; Azepines; Butyrylcholinesterase; Catalytic Domain; Cell Line, Tumor; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Free Radical Scavengers; Humans; Indoles; Molecular Docking Simulation; Molecular Structure; Neuroprotective Agents; Peptide Fragments; Protein Binding; Protein Multimerization; Structure-Activity Relationship

2019
Novel multi target-directed ligands targeting 5-HT
    European journal of medicinal chemistry, 2019, Nov-15, Volume: 182

    Topics: Alzheimer Disease; Animals; Antioxidants; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Ligands; Molecular Structure; Picrates; Reactive Oxygen Species; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Structure-Activity Relationship

2019
From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects.
    European journal of medicinal chemistry, 2021, Dec-05, Volume: 225

    Topics: Alzheimer Disease; Aminoquinolines; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Brain; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Dynamics Simulation; Molecular Structure; Neuroprotective Agents; Recombinant Proteins; Structure-Activity Relationship; tau Proteins

2021
Design, synthesis, and biological evaluation of novel (4-(1,2,4-oxadiazol-5-yl)phenyl)-2-aminoacetamide derivatives as multifunctional agents for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2022, Jan-05, Volume: 227

    Topics: Acetamides; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Biphenyl Compounds; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Structure; Neuroprotective Agents; Oxadiazoles; Picrates; Protein Aggregates; Structure-Activity Relationship

2022