donepezil and gabapentin

donepezil has been researched along with gabapentin in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (35.71)29.6817
2010's9 (64.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Buffa, C; Dallocchio, C; Mazzarello, P1
Freeman, MP; Gelenberg, AJ; Gnanadesikan, M1
Eisenach, JC; Hayashida, K; Parker, R1
Hayashida, K; Obata, H1
Eisenach, JC; Hayashida, K1
Andersen, LM; Bjerrum, OJ; Folkesson, A; Honoré, PH; Kristensen, P1
Basnet, A; Bjerrum, OJ; Butler, M; Butler, S; Gordh, TE; Honoré, PH; Kristensen, K1
Boyle, Y; Fernando, D; Kurz, H; Miller, SR; Storey, J; Zucchetto, M1
Abe, H; Hozumi, J; Ikegami, K; Inoue, R; Kawahara, K; Kogure, T; Sumitani, M; Yamada, Y1

Reviews

3 review(s) available for donepezil and gabapentin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Alternatives to lithium and divalproex in the maintenance treatment of bipolar disorder.
    Bipolar disorders, 2003, Volume: 5, Issue:3

    Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Donepezil; Fatty Acids, Omega-3; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Lamotrigine; Lithium Carbonate; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Risperidone; Thiazoles; Topiramate; Treatment Outcome; Triazines; Valproic Acid

2003
[Alpha2-adrenergic receptors in the dorsal horn of the spinal cord--their function and the descending inhibitory systems].
    Masui. The Japanese journal of anesthesiology, 2007, Volume: 56 Suppl

    Topics: Acetylcholine; Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics; Animals; Brain-Derived Neurotrophic Factor; Chronic Disease; Clonidine; Cyclohexanecarboxylic Acids; Donepezil; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Neuralgia; Norepinephrine; Piperidines; Posterior Horn Cells; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic

2007

Trials

2 trial(s) available for donepezil and gabapentin

ArticleYear
Donepezil provides positive effects to patients treated with gabapentin for neuropathic pain: an exploratory study.
    Acta anaesthesiologica Scandinavica, 2014, Volume: 58, Issue:1

    Topics: Adult; Aged; Algorithms; Amines; Analgesics; Cyclohexanecarboxylic Acids; Cyclohexanols; Donepezil; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Male; Middle Aged; Neuralgia; Neuroprotective Agents; Pain Measurement; Piperidines; Quality of Life; Sample Size; Venlafaxine Hydrochloride

2014
The effect of a combination of gabapentin and donepezil in an experimental pain model in healthy volunteers: Results of a randomized controlled trial.
    Pain, 2014, Volume: 155, Issue:12

    Topics: Adolescent; Adult; Amines; Analgesics, Non-Narcotic; Cross-Over Studies; Cyclohexanecarboxylic Acids; Donepezil; Double-Blind Method; Drug Therapy, Combination; Electric Stimulation; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Healthy Volunteers; Humans; Indans; Male; Middle Aged; Nootropic Agents; Pain; Pain Measurement; Piperidines; Skin; Sural Nerve; Young Adult

2014

Other Studies

9 other study(ies) available for donepezil and gabapentin

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Combination of donepezil and gabapentin for behavioral disorders in Alzheimer's disease.
    The Journal of clinical psychiatry, 2000, Volume: 61, Issue:1

    Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Donepezil; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Male; Mental Disorders; Piperidines; Psychiatric Status Rating Scales; Treatment Outcome

2000
Oral gabapentin activates spinal cholinergic circuits to reduce hypersensitivity after peripheral nerve injury and interacts synergistically with oral donepezil.
    Anesthesiology, 2007, Volume: 106, Issue:6

    Topics: Administration, Oral; Amines; Analgesics; Animals; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Donepezil; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Indans; Injections, Spinal; Male; Pain; Peripheral Nerve Injuries; Piperidines; Rats; Rats, Sprague-Dawley; Spinal Cord

2007
Multiplicative interactions to enhance gabapentin to treat neuropathic pain.
    European journal of pharmacology, 2008, Nov-19, Volume: 598, Issue:1-3

    Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Donepezil; Dose-Response Relationship, Drug; Drug Interactions; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Indans; Injections, Spinal; Ligation; Male; Neurotransmitter Uptake Inhibitors; Nootropic Agents; Pain; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Piperidines; Postural Balance; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Spinal Nerves; Thiophenes

2008
Low dose of donepezil improves gabapentin analgesia in the rat spared nerve injury model of neuropathic pain: single and multiple dosing studies.
    Journal of neural transmission (Vienna, Austria : 1996), 2010, Volume: 117, Issue:12

    Topics: Amines; Analgesics; Animals; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Disease Models, Animal; Donepezil; Drug Administration Schedule; Drug Combinations; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Indans; Male; Neuralgia; Peripheral Nervous System Diseases; Piperidines; Rats; Rats, Sprague-Dawley

2010
Donepezil, an Acetylcholinesterase Inhibitor, Can Attenuate Gabapentinoid-Induced Somnolence in Patients with Neuropathic Pain: A Retrospective Chart Review.
    Journal of pain & palliative care pharmacotherapy, 2017, Volume: 31, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amines; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Disorders of Excessive Somnolence; Donepezil; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Male; Middle Aged; Neuralgia; Pain Measurement; Piperidines; Pregabalin; Retrospective Studies

2017