donepezil has been researched along with ap 2238 in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrisano, V; Bartolini, M; Belluti, F; Bisi, A; Cavalli, A; Gobbi, S; Piazzi, L; Rampa, A; Recanatini, M; Valenti, P | 1 |
| Bolognesi, ML; Cavalli, A; Melchiorre, C; Minarini, A; Recanatini, M; Rosini, M; Tumiatti, V | 1 |
| Andrisano, V; Bartolini, M; Cavalli, A; Ceccarini, L; Gobbi, S; Piazzi, L; Rampa, A; Recanatini, M; Rizzo, S | 1 |
| Piplani, P; Singla, S | 1 |
| Amini, M; Edraki, N; Khan, MI; Mahdavi, M; Moghadam, FH; Nadri, H; Saeedi, M; Sameem, B | 1 |
| Cai, P; Kong, LY; Li, F; Wang, J; Wang, XB; Wu, JJ; Yang, XL | 1 |
| Akbarzadeh, T; Amini, M; Bukhari, SNA; Edraki, N; Ghobadian, R; Mahdavi, M; Moradi, A; Nadri, H; Sharifzadeh, M | 1 |
1 review(s) available for donepezil and ap 2238
| Article | Year |
|---|---|
Multi-target-directed ligands to combat neurodegenerative diseases.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Binding Sites; Calcium Channel Blockers; Chelating Agents; Cholinesterase Inhibitors; Humans; Huntington Disease; Ligands; Multiple Sclerosis; Neurodegenerative Diseases; Neurofibrillary Tangles; Neurotransmitter Agents; Parkinson Disease; Plaque, Amyloid | 2008 |
6 other study(ies) available for donepezil and ap 2238
| Article | Year |
|---|---|
3-(4-[[Benzyl(methyl)amino]methyl]phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation: a dual function lead for Alzheimer's disease therapy.
Topics: Acetylcholinesterase; Acetylthiocholine; Alzheimer Disease; Amyloid beta-Peptides; Benzopyrans; Benzylamines; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Coumarins; Fluorometry; Humans; Hydrolysis; Models, Molecular; Structure-Activity Relationship | 2003 |
Targeting Alzheimer's disease: Novel indanone hybrids bearing a pharmacophoric fragment of AP2238.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Combined Chemotherapy Protocols; Benzylamines; Binding Sites; Bleomycin; Cholinesterase Inhibitors; Computer Simulation; Coumarins; Donepezil; Humans; Indans; Lomustine; Methotrexate; Peptide Fragments; Piperidines; Recombinant Proteins; Stilbenes; Structure-Activity Relationship; Tetrahydronaphthalenes | 2010 |
Coumarin derivatives as potential inhibitors of acetylcholinesterase: Synthesis, molecular docking and biological studies.
Topics: Acetylcholinesterase; Amnesia; Animals; Cholinesterase Inhibitors; Coumarins; Humans; Mice; Molecular Docking Simulation; Oxidative Stress; Spatial Memory; Structure-Activity Relationship | 2016 |
Synthesis, docking study and neuroprotective effects of some novel pyrano[3,2-c]chromene derivatives bearing morpholine/phenylpiperazine moiety.
Topics: Animals; Apoptosis; Benzopyrans; Cholinesterase Inhibitors; Molecular Docking Simulation; Morpholines; Neuroprotective Agents; PC12 Cells; Piperazines; Rats | 2017 |
Novel cinnamamide-dibenzylamine hybrids: Potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Benzylamines; Blood-Retinal Barrier; Butyrylcholinesterase; Cell Death; Cholinergic Agents; Cholinesterase Inhibitors; Cinnamates; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Rats; Structure-Activity Relationship | 2017 |
Novel tetrahydrocarbazole benzyl pyridine hybrids as potent and selective butryl cholinesterase inhibitors with neuroprotective and β-secretase inhibition activities.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Butyrylcholinesterase; Carbazoles; Dose-Response Relationship, Drug; Enzyme Inhibitors; Horses; Molecular Structure; Neuroprotective Agents; Protein Aggregates; Pyridines; Structure-Activity Relationship; Torpedo | 2018 |