donepezil has been researched along with amyloid beta-peptides in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 9 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akasofu, S; Kimura, M; Ogura, H; Sawada, K | 1 |
| Dohniwa, M; Kamei, H; Kobayashi, K; Nabeshima, T; Nagai, T; Ohhara, T; Takayanagi, M; Takuma, K; Yamada, K; Yoshida, S | 1 |
| Doganay, G; Georgiou, G; Khalil, Z; Khodr, B | 1 |
| Alkam, T; Furukawa-Hibi, Y; Greig, NH; Matsuyama, A; Mizoguchi, H; Moussaoui, S; Nagai, T; Nitta, A; Suzuki, K; Yamada, K; Yu, QS | 1 |
| Choi, SH; Hwang, SH; Jang, CG; Kang, J; Kim, HC; Kim, HJ; Kwon, SH; Lee, BH; Lee, JH; Nah, SY; Shin, EJ; Shin, TJ | 1 |
| Huang, L; Li, X; Liu, A; Lu, C; Luo, HB; Luo, Z; Sheng, J; Sun, Y; Yan, J | 1 |
| Borjini, N; Gillis, C; Maurice, T; Meunier, J; Villard, V | 1 |
| Aisen, PS; Donohue, MC; Edland, SD; Galasko, D; Moghadam, SH; Petersen, RC; Rissman, RA; Roe, AD; Sano, M; Sun, CK; Thomas, RG | 1 |
| Cheng, YF; Guo, HB; Qiu, ZK; Wang, CM; Wang, HT; Wu, JG; Xu, JP; Zhang, C | 1 |
| Baysal, I; Gultekinoglu, M; Ucar, G; Ulubayram, K; Yabanoglu-Ciftci, S | 1 |
| Cai, P; Kong, LY; Liu, QH; Wang, XB; Wang, ZM; Wu, JJ; Xu, DQ; Yang, XL | 1 |
| Zigman, WB | 1 |
1 review(s) available for donepezil and amyloid beta-peptides
| Article | Year |
|---|---|
Atypical aging in Down syndrome.
Topics: Adult; Aging; Alzheimer Disease; Amyloid beta-Peptides; Cholinesterase Inhibitors; Dementia; Donepezil; Down Syndrome; Female; Humans; Incidence; Indans; Intellectual Disability; Male; Metabolic Syndrome; Middle Aged; Nootropic Agents; Oxidative Stress; Peptide Fragments; Phenotype; Piperidines; Prevalence; Telomere Shortening; Treatment Outcome; United States | 2013 |
1 trial(s) available for donepezil and amyloid beta-peptides
| Article | Year |
|---|---|
Longitudinal plasma amyloid beta in Alzheimer's disease clinical trials.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Apolipoprotein E4; Biomarkers; Blood Chemical Analysis; Cognitive Dysfunction; Disease Progression; Donepezil; Female; Heterozygote; Humans; Indans; Longitudinal Studies; Male; Nootropic Agents; Peptide Fragments; Piperidines; Severity of Illness Index; Simvastatin; Vitamin E | 2015 |
10 other study(ies) available for donepezil and amyloid beta-peptides
| Article | Year |
|---|---|
Protective effect of donepezil against Abeta(1-40) neurotoxicity in rat septal neurons.
Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Cells, Cultured; Cholinergic Fibers; Cholinesterase Inhibitors; Donepezil; Down-Regulation; Fluorescent Dyes; Immunohistochemistry; Indans; L-Lactate Dehydrogenase; Membrane Transport Proteins; Molecular Structure; Neurons; Neuroprotective Agents; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Septal Nuclei; Thiazoles; Vesicular Acetylcholine Transport Proteins | 2005 |
Effects of memantine and donepezil on amyloid beta-induced memory impairment in a delayed-matching to position task in rats.
Topics: Amyloid beta-Peptides; Animals; Cholinesterase Inhibitors; Conditioning, Operant; Donepezil; Drug Administration Routes; Drug Interactions; Excitatory Amino Acid Antagonists; Food Deprivation; Hippocampus; Indans; Male; Memantine; Memory Disorders; Peptide Fragments; Piperidines; Rats; Rats, Inbred F344; Reaction Time; Time Factors | 2005 |
Pharmacological manipulation of the vasoconstrictive effects of amyloid-beta peptides by donepezil and rivastigmine.
Topics: Amyloid beta-Peptides; Animals; Donepezil; Hindlimb; Indans; Male; Peptide Fragments; Phenylcarbamates; Piperidines; Rats; Rats, Sprague-Dawley; Rivastigmine; Vasoconstriction | 2006 |
Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-β peptide in mice.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Cognition Disorders; Disease Models, Animal; Donepezil; Dose-Response Relationship, Drug; Indans; Male; Mice; Mice, Inbred ICR; Motor Activity; Peptide Fragments; Phenylcarbamates; Piperidines; Recognition, Psychology; Rivastigmine | 2011 |
Gintonin, a ginseng-derived lysophosphatidic acid receptor ligand, attenuates Alzheimer's disease-related neuropathies: involvement of non-amyloidogenic processing.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Brain; Calcium; Calcium-Binding Proteins; Cell Survival; Disease Models, Animal; Donepezil; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Glycoproteins; Humans; Indans; Isoxazoles; Ligands; Maze Learning; Memory Disorders; Metalloproteases; Mice; Mice, Transgenic; Microfilament Proteins; Mutation; Neuroblastoma; Nootropic Agents; Panax; Peptide Fragments; Phytotherapy; Piperidines; Plant Proteins; Presenilin-1; Propionates; Protein Binding; Receptors, Lysophosphatidic Acid; Signal Transduction; Time Factors; Transfection | 2012 |
Synthesis and evaluation of multi-target-directed ligands against Alzheimer's disease based on the fusion of donepezil and ebselen.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Azoles; Butyrylcholinesterase; Chemistry Techniques, Synthetic; Cholinesterase Inhibitors; Donepezil; Electrophorus; Glutathione Peroxidase; Humans; Indans; Isoindoles; Kinetics; Ligands; Mice; Molecular Docking Simulation; Molecular Targeted Therapy; Organoselenium Compounds; Peptide Fragments; Peroxynitrous Acid; Piperidines; Protein Multimerization; Protein Structure, Secondary; Thioredoxin-Disulfide Reductase; Toxicity Tests, Acute | 2013 |
Brain toxicity and inflammation induced in vivo in mice by the amyloid-β forty-two inducer aftin-4, a roscovitine derivative.
Topics: Adenine; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Butyrates; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Encephalitis; Enzyme Inhibitors; Hippocampus; Hydrocarbons, Halogenated; Ibuprofen; Indans; Learning Disabilities; Male; Memory Disorders; Mice; Neuroprotective Agents; Oxidative Stress; Peptide Fragments; Piperidines | 2015 |
Donepezil improves learning and memory deficits in APP/PS1 mice by inhibition of microglial activation.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Brain; Cytokines; Donepezil; Indans; Learning Disabilities; Male; Maze Learning; Memory Disorders; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neurites; Nootropic Agents; Peptide Fragments; Piperidines; Plaque, Amyloid; Presenilin-1; Random Allocation; Recognition, Psychology | 2015 |
Donepezil loaded PLGA-b-PEG nanoparticles: their ability to induce destabilization of amyloid fibrils and to cross blood brain barrier in vitro.
Topics: Amyloid; Amyloid beta-Peptides; Astrocytes; Blood-Brain Barrier; Capillary Permeability; Cell Line; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Drug Carriers; Endothelial Cells; Gene Expression; Humans; Indans; Nanoparticles; Neuroprotective Agents; Peptide Fragments; Piperidines; Polyethylene Glycols; Polyglactin 910; Protein Stability; Rifampin | 2017 |
Rational modification of donepezil as multifunctional acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell Survival; Cholinesterase Inhibitors; Copper; Donepezil; Drug Design; Humans; Indans; Kinetics; Liver; Mice; Models, Molecular; Peptide Fragments; Piperidines; Protein Aggregates; Protein Conformation | 2016 |