domperidone and prazosin

domperidone has been researched along with prazosin in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199012 (46.15)18.7374
1990's2 (7.69)18.2507
2000's5 (19.23)29.6817
2010's5 (19.23)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Janssen, CG; Laduron, PM; Thijssen, JB; Van Dun, J; Wouters, W1
Andrews, PR; Craik, DJ; Martin, JL1
Topliss, JG; Yoshida, F1
Nagashima, R; Nishikawa, T; Tobita, M1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Sen, S; Sinha, N1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Esaki, T; Kawashima, H; Komura, H; Kuroda, M; Mizuguchi, K; Natsume-Kitatani, Y; Ohashi, R; Watanabe, R1
Acevedo, O; Dasararaju, G; Devadasan, V; Halakova, D; Jayaprakash, V; Kovacikova, L; Mohd Siddique, MU; Mondal, SK; Prnova, MS; Shilkar, D; Stefek, M; Thakur, A; Yasmin, S1
Martínez, JA; Milanés, MV; Vargas, ML1
Fujiwara, M; Nishikawa, H; Taniguchi, T; Yokotani, K1
Greiner, HE; Haase, A; Klockow, M; Schmitges, CJ; Seyfried, C1
Emi, S; Hikasa, Y; Ogasawara, S; Takase, K1
Böhmer, G; Gouzoulis, E; Löffelholz, K; Raach, M; Schmid, K1
Carroll, JD; Itoh, H; Lang, RM; Nakamura, S; Rajfer, SI1
Delpierre, S; Grimaud, C; Guillot, C; Peyrot, J1
Schuurkes, JA; Van Nueten, JM3
Bohmann, C; Riera-Knorrenschild, G; Rump, LC; Schollmeyer, P; Schwertfeger, E; Spillner, G1
Rossi, NF1

Other Studies

26 other study(ies) available for domperidone and prazosin

ArticleYear
In vitro labeling of serotonin-S2 receptors: synthesis and binding characteristics of [3H]-7-aminoketanserin.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:9

    Topics: Animals; Binding, Competitive; Brain; Chemical Phenomena; Chemistry; Frontal Lobe; Guinea Pigs; Ketanserin; Kinetics; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin

1986
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of an
    Journal of medicinal chemistry, 2021, 03-11, Volume: 64, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Cell Line; Computer Simulation; Endothelial Cells; Gene Knockout Techniques; Humans; Organic Chemicals; Rats, Transgenic

2021
Non-carboxylic acid inhibitors of aldose reductase based on N-substituted thiazolidinedione derivatives.
    European journal of medicinal chemistry, 2021, Nov-05, Volume: 223

    Topics: Aldehyde Reductase; Animals; Caco-2 Cells; Catalytic Domain; Dogs; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Madin Darby Canine Kidney Cells; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Rats, Wistar; Structure-Activity Relationship; Thiazolidinediones

2021
Influence of dopaminergic and noradrenergic systems on the release of opioid peptides in guinea-pig ileum.
    The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:9

    Topics: Adrenergic alpha-Antagonists; Animals; Domperidone; Dopamine; Endorphins; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Myenteric Plexus; Naloxone; Norepinephrine; Piperidines; Prazosin; Receptors, Dopamine; Yohimbine

1989
The bindings of 3H-prazosin and 3H-yohimbine to alpha adrenoceptors in the guinea-pig stomach.
    Life sciences, 1988, Volume: 42, Issue:23

    Topics: Animals; Apomorphine; Binding, Competitive; Cell Membrane; Domperidone; Dopamine; Gastric Mucosa; Guinea Pigs; Male; Prazosin; Receptors, Adrenergic, alpha; Spiperone; Sympatholytics; Sympathomimetics; Tritium; Yohimbine

1988
Studies on the receptor profile of bisoprolol.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Bisoprolol; Cattle; Dihydroalprenolol; Domperidone; Humans; In Vitro Techniques; Ketanserin; Male; Piperidines; Prazosin; Propanolamines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Histamine; Receptors, Muscarinic; Spiperone; Tetrahydronaphthalenes; Yohimbine

1986
Antagonistic effects of alpha-adrenoceptor blocking agents on reticuloruminal hypomotility induced by xylazine in cattle.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1988, Volume: 52, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Cattle; Domperidone; Female; Gastrointestinal Motility; Naloxone; Prazosin; Reticulum; Rumen; Thiazines; Tolazoline; Xylazine; Yohimbine

1988
Dopaminergic control of respiration as shown by effects of 4-aminopyridine.
    European journal of pharmacology, 1986, Jan-29, Volume: 120, Issue:3

    Topics: 4-Aminopyridine; Aminopyridines; Anesthesia; Animals; Atropine; Domperidone; Dopamine; Haloperidol; Hemodynamics; Neuromuscular Depolarizing Agents; Phrenic Nerve; Prazosin; Rabbits; Respiration; Salivation; Vagotomy

1986
Role of adrenoceptors and dopamine receptors in modulating left ventricular diastolic function.
    Circulation research, 1988, Volume: 63, Issue:1

    Topics: Animals; Diastole; Dobutamine; Dogs; Domperidone; Dopamine; Hemodynamics; Myocardial Contraction; Prazosin; Receptors, Adrenergic; Receptors, Dopamine; Systole; Ventricular Function; Yohimbine

1988
Ventilatory effects of domperidone, a new dopamine antagonist, in anaesthetized rabbits.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 275, Issue:1

    Topics: Anesthesia; Animals; Blood Gas Analysis; Carbon Dioxide; Domperidone; Dopamine Antagonists; Heart Rate; Hydrogen-Ion Concentration; Hypoxia; Oxygen Consumption; Prazosin; Rabbits; Respiration

1985
Effects of dopamine and its antagonist domperidone cannot be explained by an effect on alpha 1-adrenergic receptors.
    Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 250, Issue:2

    Topics: Animals; Benzimidazoles; Domperidone; Dopamine; Dopamine Antagonists; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Phenylephrine; Piperidines; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Stomach

1981
Dose-dependent stimulation of antroduodenal coordination by domperidone via specific dopamine-receptors.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 256, Issue:2

    Topics: Animals; Domperidone; Duodenum; Guinea Pigs; In Vitro Techniques; Peristalsis; Prazosin; Propranolol; Pyloric Antrum; Receptors, Adrenergic, alpha; Receptors, Dopamine; Stimulation, Chemical

1982
Is dopamine an inhibitory modulator of gastrointestinal motility?
    Scandinavian journal of gastroenterology. Supplement, 1981, Volume: 67

    Topics: Animals; Benzimidazoles; Domperidone; Dopamine; Dopamine Antagonists; Gastrointestinal Motility; Guinea Pigs; Piperidines; Prazosin

1981
Dopaminergic and alpha-adrenergic control of neurotransmission in human right atrium.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Benzazepines; Brimonidine Tartrate; Domperidone; Dopamine Agonists; Dopamine Antagonists; Electric Stimulation; Ergolines; Female; Fenoldopam; Heart Atria; Humans; In Vitro Techniques; Male; Methoxamine; Middle Aged; Norepinephrine; Prazosin; Quinoxalines; Quinpirole; Receptors, Adrenergic, alpha; Receptors, Dopamine; Sulpiride; Synaptic Transmission; Yohimbine

1995
Dopaminergic control of angiotensin II-induced vasopressin secretion in vitro.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Angiotensin II; Animals; Apomorphine; Arginine Vasopressin; Benzazepines; Domperidone; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Hypothalamo-Hypophyseal System; Kinetics; Male; Models, Neurological; Organ Culture Techniques; Phenoxybenzamine; Prazosin; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Receptors, Dopamine D2; Time Factors

1998