domperidone and ondansetron

domperidone has been researched along with ondansetron in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (24.14)18.2507
2000's6 (20.69)29.6817
2010's13 (44.83)24.3611
2020's3 (10.34)2.80

Authors

AuthorsStudies
Mol, CA; Schinkel, AH; van Deemter, L; Wagenaar, E1
Hirokawa, Y; Kato, S; Morie, T; Yamazaki, H; Yoshida, N1
Topliss, JG; Yoshida, F1
Fujiwara, I; Harada, H; Hirokawa, Y; Kato, S; Suzuki, K; Yoshida, N; Yoshikawa, T1
Nagashima, R; Nishikawa, T; Tobita, M1
Lombardo, F; Obach, RS; Waters, NJ1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Sen, S; Sinha, N1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Carruthers, L; Coombes, RC; Davenport, J; Dougherty, L; Evans, C; Stein, RC1
Borm, JJ; Esseboom, EU; Rojer, RA; Statius van Eps, LW1
Fukuda, T; Haga, K; Inaba, K; Morimoto, Y; Setoguchi, M; Shoji, H1
Hasegawa, S; Matsunaga, T; Morita, M; Takeda, N1
Andrews, PL; Cheng, FH; Moreaux, B; Ngan, MP; Rudd, JA; Sam, TS; Wai, MK; Wan, C1
Carius, R; Kiess, W; Kostev, K; Pfeil, N; Schröder, H; Uhlig, HH; Uhlig, U1
Arora, A; Goel, H; Rana, V; Tiwary, AK1
Arrighini, A; Bertolani, P; Biban, P; Bonati, M; Clavenna, A; Da Dalt, L; Di Pietro, P; Guala, A; Maestro, A; Mannelli, F; Marchetti, F; Messi, G; Pazzaglia, A; Perri, F; Reale, A; Renna, S; Ronfani, L; Rovere, F; Tondelli, MT; Urbino, AF; Valletta, E; Vitale, A; Zangardi, T; Zanon, D1
Kakiuchi, H; Kawarai-Shimamura, A; Kuwagata, M; Orito, K1
Nagar, S; Parkman, HP; Youssef, AS1
Furyk, JS; McKenzie, S; Meek, R1
Ha, HS; Lee, JM; Nam, Y; Sohn, UD; Wang, Y1
Arrighini, A; Barbi, E; Bertolani, P; Biban, P; Bonati, M; Clavenna, A; Da Dalt, L; Guala, A; Maestro, A; Marchetti, F; Mazzoni, E; Pazzaglia, A; Perri, PF; Reale, A; Renna, S; Ronfani, L; Rovere, F; Urbino, AF; Valletta, E; Vitale, A; Zangardi, T; Zanon, D1
Dechering, DG; Eckardt, L; Ellermann, C; Fehr, M; Fischer, C; Frommeyer, G; Kochhäuser, S; Lange, PS1
Dechering, DG; Eckardt, L; Ellermann, C; Fehr, M; Fischer, C; Frommeyer, G; Kochhäuser, S; Lange, PS; Wasmer, K1
Acosta-Reyes, J; Florez, ID; Niño-Serna, LF; Veroniki, AA1
Banerjee, S; Kamath, A; Rai, KM; Saxena, PUP; Shreyas, R1
Daneshfar, A; Khezeli, T1

Reviews

1 review(s) available for domperidone and ondansetron

ArticleYear
Antiemetics in Children With Acute Gastroenteritis: A Meta-analysis.
    Pediatrics, 2020, Volume: 145, Issue:4

    Topics: Acute Disease; Antiemetics; Child; Child, Preschool; Dexamethasone; Diarrhea; Dimenhydrinate; Domperidone; Fluid Therapy; Gastroenteritis; Granisetron; Hospitalization; Humans; Infant; Metoclopramide; Network Meta-Analysis; Ondansetron; Randomized Controlled Trials as Topic; Regression Analysis; Vomiting

2020

Trials

4 trial(s) available for domperidone and ondansetron

ArticleYear
Comparison of ondansetron with dexamethasone and domperidone in the prophylaxis of non-cisplatin chemotherapy induced emesis refractory to dexamethasone.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Dexamethasone; Domperidone; Female; Humans; Imidazoles; Male; Middle Aged; Ondansetron

1991
Prophylaxis of delayed nausea and vomiting after cancer chemotherapy.
    The Netherlands journal of medicine, 1995, Volume: 47, Issue:1

    Topics: Adult; Aged; Chi-Square Distribution; Cisplatin; Domperidone; Double-Blind Method; Female; Humans; Middle Aged; Nausea; Neoplasms; Ondansetron; Vomiting

1995
Oral ondansetron versus domperidone for symptomatic treatment of vomiting during acute gastroenteritis in children: multicentre randomized controlled trial.
    BMC pediatrics, 2011, Feb-10, Volume: 11

    Topics: Acute Disease; Administration, Oral; Antiemetics; Child; Child, Preschool; Clinical Protocols; Domperidone; Double-Blind Method; Drug Administration Schedule; Female; Fluid Therapy; Gastroenteritis; Humans; Infant; Male; Ondansetron; Treatment Outcome; Vomiting

2011
Oral Ondansetron versus Domperidone for Acute Gastroenteritis in Pediatric Emergency Departments: Multicenter Double Blind Randomized Controlled Trial.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Acute Disease; Administration, Oral; Antiemetics; Child; Child, Preschool; Domperidone; Double-Blind Method; Emergency Medical Services; Emergency Service, Hospital; Female; Gastroenteritis; Humans; Infant; Male; Ondansetron; Placebo Effect; Prospective Studies; Treatment Outcome; Vomiting

2016

Other Studies

24 other study(ies) available for domperidone and ondansetron

ArticleYear
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.
    The Journal of clinical investigation, 1996, Jun-01, Volume: 97, Issue:11

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Cell Line; Clozapine; Diffusion; Domperidone; Epithelium; Flunitrazepam; Haloperidol; Humans; Kidney; Kinetics; Loperamide; Male; Mice; Mice, Inbred Strains; Ondansetron; Phenytoin; Recombinant Proteins; Structure-Activity Relationship; Swine; Tissue Distribution; Transfection

1996
A novel series of N-(hexahydro-1,4-diazepin-6-yl) and N-(hexahydroazepin- 3-yl)benzamides with high affinity for 5-HT3 and dopamine D2 receptors.
    Bioorganic & medicinal chemistry letters, 1998, Mar-17, Volume: 8, Issue:6

    Topics: Animals; Benzamides; Binding Sites; Cerebral Cortex; Corpus Striatum; Domperidone; Dopamine Antagonists; Imidazoles; Indoles; Ligands; Metoclopramide; Models, Chemical; Ondansetron; Rats; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Spiperone; Stereoisomerism

1998
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activity.
    Journal of medicinal chemistry, 2003, Feb-27, Volume: 46, Issue:5

    Topics: Animals; Antiemetics; Azepines; Brain; Crystallography, X-Ray; Dogs; Dopamine Antagonists; Ferrets; In Vitro Techniques; Models, Molecular; Pyridines; Rats; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Stereoisomerism; Structure-Activity Relationship

2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The effects of orally administered Y-25130, a selective serotonin3-receptor antagonist, on chemotherapeutic agent-induced emesis.
    Japanese journal of pharmacology, 1993, Volume: 63, Issue:3

    Topics: Administration, Oral; Animals; Antiemetics; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisplatin; Cyclophosphamide; Dogs; Domperidone; Dose-Response Relationship, Drug; Doxorubicin; Female; Ferrets; Granisetron; Male; Metoclopramide; Ondansetron; Oxazines; Serotonin Antagonists; Vomiting

1993
Pica in rats is analogous to emesis: an animal model in emesis research.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:4

    Topics: Animals; Antiemetics; Apomorphine; Cisplatin; Copper; Copper Sulfate; Disease Models, Animal; Domperidone; Dose-Response Relationship, Drug; Food; Kaolin; Male; Ondansetron; Pica; Rats; Rats, Wistar; Vomiting

1993
Radiation-induced emesis: a prospective observational multicenter Italian trial. The Italian Group for Antiemetic Research in Radiotherapy.
    International journal of radiation oncology, biology, physics, 1999, Jun-01, Volume: 44, Issue:3

    Topics: Adult; Antiemetics; Domperidone; Drug Administration Schedule; Female; Humans; Incidence; Indoles; Male; Metoclopramide; Middle Aged; Nausea; Ondansetron; Prognosis; Prospective Studies; Radiotherapy; Sex Factors; Time Factors; Tropisetron; Vomiting

1999
Evaluation of the anti-emetic potential of anti-migraine drugs to prevent resiniferatoxin-induced emesis in Suncus murinus (house musk shrew).
    European journal of pharmacology, 2005, Jan-31, Volume: 508, Issue:1-3

    Topics: Animals; Antiemetics; Butanols; Capsaicin; Cyclooxygenase Inhibitors; Dihydroergotamine; Diphenhydramine; Diterpenes; Domperidone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Indomethacin; Malates; Methysergide; Metoclopramide; Migraine Disorders; Ondansetron; Piperidines; Ruthenium Red; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists; Shrews; Sumatriptan; Time Factors; Tropanes; Vomiting

2005
Antiemetic medications in children with presumed infectious gastroenteritis--pharmacoepidemiology in Europe and Northern America.
    The Journal of pediatrics, 2008, Volume: 153, Issue:5

    Topics: Antiemetics; Child; Child, Preschool; Dimenhydrinate; Diphenhydramine; Domperidone; Europe; Female; Gastroenteritis; Humans; Infant; Infant, Newborn; Male; North America; Ondansetron; Pharmacoepidemiology; Promethazine; Retrospective Studies

2008
Development and evaluation of mathematical model to predict disintegration time of fast disintegrating tablets using powder characteristics.
    Pharmaceutical development and technology, 2011, Volume: 16, Issue:1

    Topics: Adsorption; Chemistry, Pharmaceutical; Chitosan; Compressive Strength; Domperidone; Drug Stability; Excipients; Glycine; Metoclopramide; Models, Chemical; Ondansetron; Powders; Solubility; Tablets; Time Factors; Water

2011
Tranexamic acid induces kaolin intake stimulating a pathway involving tachykinin neurokinin 1 receptors in rats.
    European journal of pharmacology, 2014, Jan-15, Volume: 723

    Topics: Animals; Antiemetics; Antifibrinolytic Agents; Aprepitant; Area Postrema; Domperidone; Dopamine Antagonists; Kaolin; Male; Morpholines; Neurokinin-1 Receptor Antagonists; Ondansetron; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Neurokinin-1; Serotonin Antagonists; Solitary Nucleus; Tranexamic Acid

2014
Domperidone interacts with pioglitazone but not with ondansetron via common CYP metabolism in vitro.
    Xenobiotica; the fate of foreign compounds in biological systems, 2014, Volume: 44, Issue:9

    Topics: Antiemetics; Chromatography, Liquid; Cytochrome P-450 CYP3A; Domperidone; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Gastrointestinal Agents; Humans; Hydroxylation; Hypoglycemic Agents; Microsomes, Liver; Ondansetron; Pioglitazone; Tandem Mass Spectrometry; Thiazolidinediones

2014
Drug treatment of adults with nausea and vomiting in primary care.
    BMJ (Clinical research ed.), 2014, Aug-07, Volume: 349

    Topics: Adult; Antiemetics; Domperidone; Droperidol; Female; Histamine Antagonists; Humans; Male; Metoclopramide; Morning Sickness; Muscarinic Antagonists; Nausea; Ondansetron; Pregnancy; Primary Health Care; Prochlorperazine; Promethazine; Scopolamine; Vomiting

2014
The effect of Flos Lonicerae Japonicae extract on gastro-intestinal motility function.
    Journal of ethnopharmacology, 2016, Feb-17, Volume: 179

    Topics: Animals; Benzamides; Carbachol; Cats; Cells, Cultured; Domperidone; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Esophageal Sphincter, Lower; Gastric Emptying; Gastrointestinal Motility; Gastrointestinal Transit; Herb-Drug Interactions; Indoles; Lonicera; Male; Morpholines; Muscle Contraction; Muscle, Smooth; Ondansetron; Plant Extracts; Rats; Sulfonamides

2016
Severe Proarrhythmic Potential of the Antiemetic Agents Ondansetron and Domperidone.
    Cardiovascular toxicology, 2017, Volume: 17, Issue:4

    Topics: Animals; Antiemetics; Arrhythmias, Cardiac; Domperidone; Dose-Response Relationship, Drug; Female; Ondansetron; Rabbits; Severity of Illness Index

2017
Additive Proarrhythmic Effect of Combined Treatment with QT-Prolonging Agents.
    Cardiovascular toxicology, 2018, Volume: 18, Issue:1

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Domperidone; Drug Interactions; Erythromycin; Female; Heart Conduction System; Heart Rate; Isolated Heart Preparation; Ondansetron; Proof of Concept Study; Rabbits; Time Factors; Trimethoprim, Sulfamethoxazole Drug Combination

2018
Effect of domperidone, ondansetron, olanzapine-containing antiemetic regimen on QT
    Scientific reports, 2021, 01-11, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Domperidone; Drug Combinations; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Middle Aged; Nausea; Neoplasms; Olanzapine; Ondansetron; Prospective Studies; Single-Blind Method; Young Adult

2021
Vortex-assisted dispersive solid-phase microextraction of ondansetron and domperidone using carbonized cockle shell modified with nitrogen and sulfur-doped carbon dots as a bio-based sorbent.
    Journal of separation science, 2022, Volume: 45, Issue:18

    Topics: Animals; Antiemetics; Carbon; Cardiidae; Domperidone; Limit of Detection; Liquid Phase Microextraction; Nitrogen; Ondansetron; Pharmaceutical Preparations; Solid Phase Extraction; Sulfur

2022