domperidone and naloxone

domperidone has been researched along with naloxone in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199017 (50.00)18.7374
1990's2 (5.88)18.2507
2000's9 (26.47)29.6817
2010's5 (14.71)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Lefebvre, RA; Willems, JL1
Aguila, MC; Marubayashi, U; McCann, SM1
Lang, IM; Marvig, J1
Hikasa, Y; Ogasawara, S; Takase, K1
Martínez, JA; Milanés, MV; Vargas, ML1
Peter, RE; Rosenblum, PM1
Emi, S; Hikasa, Y; Ogasawara, S; Takase, K1
Baxter, AJ; Read, NW; Welch, IM1
Eneroth, P; Forsberg, G; Södersten, P1
Betti, R; Casanueva, FF; Cella, SG; Müller, EE1
Ben Natan, L; Costentin, J; Gonzales-Rios, F; Protais, P; Vlaiculescu, A1
Blancquaert, JP; Lefebvre, RA; Willems, JL1
McCallum, RW1
Cocchi, D; Locatelli, V; Müller, EE; Novelli, A; Parenti, M; Peñalva, A1
Carter, DA; Cooper, JS; Inkster, SE; Whitehead, SA1
Cairnie, AB; Leach, KE1
Lightman, SL1
Faden, AI; Feuerstein, G; Holaday, JW; Jacobs, TP1
Farzin, D1
Asad, M; Ramaswamy, S; Shashindran, C; Shewade, DG; Topno, I1
Ramaswamy, S; Reddy, PM; Shashindran, CH; Sivasanker, M1
Brezovec, S; Ferrero, EA; Lorenzon, S1
Kumei, S; Miyagishi, S; Nozu, R; Nozu, T; Okumura, T; Takakusaki, K1
Fu, F; Li, B; Li, T; Wang, D; Wang, L; Wang, T; Zhang, L1

Other Studies

34 other study(ies) available for domperidone and naloxone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Gastric relaxation by morphine, apomorphine and fentanyl in the conscious dog.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 242, Issue:2

    Topics: Animals; Apomorphine; Benzimidazoles; Dogs; Domperidone; Fentanyl; Haloperidol; Morphine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naloxone; Piperidines; Stomach; Vomiting

1979
The effect of galanin on growth hormone-releasing factor and somatostatin release from median eminence fragments in vitro.
    Neuroendocrinology, 1992, Volume: 56, Issue:6

    Topics: Animals; Domperidone; Dose-Response Relationship, Drug; Galanin; Growth Hormone-Releasing Hormone; Male; Median Eminence; Naloxone; Peptides; Phentolamine; Pimozide; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Somatostatin

1992
Functional localization of specific receptors mediating gastrointestinal motor correlates of vomiting.
    The American journal of physiology, 1989, Volume: 256, Issue:1 Pt 1

    Topics: Animals; Apomorphine; Atropine; Copper; Copper Sulfate; Digestive System; Dogs; Domperidone; Female; Gastrointestinal Motility; Haloperidol; Hexamethonium; Hexamethonium Compounds; Male; Muscle Contraction; Naloxone; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Serotonin; Serotonin Antagonists; Sincalide; Vomiting

1989
Evidence for the involvement of alpha 2-adrenoceptors in the emetic action of xylazine in cats.
    American journal of veterinary research, 1989, Volume: 50, Issue:8

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Cat Diseases; Cats; Chlorpromazine; Diphenhydramine; Domperidone; Female; Hydroxydopamines; Male; Naloxone; Oxidopamine; Propranolol; Random Allocation; Receptors, Adrenergic, alpha; Thiazines; Vomiting; Xylazine

1989
Influence of dopaminergic and noradrenergic systems on the release of opioid peptides in guinea-pig ileum.
    The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:9

    Topics: Adrenergic alpha-Antagonists; Animals; Domperidone; Dopamine; Endorphins; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Myenteric Plexus; Naloxone; Norepinephrine; Piperidines; Prazosin; Receptors, Dopamine; Yohimbine

1989
Evidence for the involvement of endogenous opioids in the regulation of gonadotropin secretion in male goldfish, Carassius auratus.
    General and comparative endocrinology, 1989, Volume: 73, Issue:1

    Topics: Animals; Cyprinidae; Domperidone; Dopamine; Endorphins; Goldfish; Gonadotropin-Releasing Hormone; Gonadotropins; Male; Naloxone

1989
Antagonistic effects of alpha-adrenoceptor blocking agents on reticuloruminal hypomotility induced by xylazine in cattle.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1988, Volume: 52, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Cattle; Domperidone; Female; Gastrointestinal Motility; Naloxone; Prazosin; Reticulum; Rumen; Thiazines; Tolazoline; Xylazine; Yohimbine

1988
Effect of naloxone, domperidone and idazoxan on the delay in gastric emptying induced by ileal lipid.
    Alimentary pharmacology & therapeutics, 1987, Volume: 1, Issue:5

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Dioxanes; Domperidone; Emulsions; Gastric Emptying; Humans; Idazoxan; Ileum; Intubation, Gastrointestinal; Lipid Metabolism; Male; Naloxone

1987
Naloxone stimulates sexual behaviour in lactating rats.
    The Journal of endocrinology, 1987, Volume: 113, Issue:3

    Topics: Adrenalectomy; Animals; beta-Endorphin; Cervix Uteri; Domperidone; Endorphins; Estradiol; Female; Lactation; Lordosis; Naloxone; Ovariectomy; Pregnancy; Progesterone; Rats; Rats, Inbred Strains; Sexual Behavior, Animal

1987
Activation of the cholinergic system and growth hormone release in the dog: functional interactions with other neurotransmitters.
    Acta endocrinologica, 1985, Volume: 108, Issue:1

    Topics: Animals; Behavior, Animal; Cimetidine; Clemastine; Diphenhydramine; Dogs; Domperidone; Female; Fenfluramine; Growth Hormone; Male; Metergoline; Naloxone; Phentolamine; Physostigmine; Pimozide; Pizotyline; Propranolol; Radioimmunoassay; Receptors, Cholinergic; Synaptic Transmission

1985
Dissociated effects of apomorphine on various nociceptive responses in mice.
    Journal of neural transmission, 1986, Volume: 67, Issue:1-2

    Topics: Analgesics; Animals; Apomorphine; Body Temperature; Domperidone; Dopamine; Haloperidol; Male; Mice; Naloxone; Pain Measurement; Sulpiride

1986
Influence of peripheral and central administration of apomorphine and morphine on intragastric pressure in the dog.
    European journal of pharmacology, 1985, Jan-02, Volume: 107, Issue:2

    Topics: Animals; Apomorphine; Brain; Chemoreceptor Cells; Dogs; Domperidone; Female; Injections, Intravenous; Injections, Intraventricular; Morphine; Naloxone; Pressure; Stomach; Vomiting

1985
Review of the current status of prokinetic agents in gastroenterology.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:12

    Topics: Benzamides; Chemical Phenomena; Chemistry; Cisapride; Dexamethasone; Digestive System; Domperidone; Gastric Emptying; Gastroesophageal Reflux; Gastrointestinal Diseases; Gastrointestinal Motility; Humans; Kinetics; Metoclopramide; Naloxone; Phenytoin; Piperidines; Proglumide; Vomiting

1985
Hypothalamic neurotransmitter function in experimentally induced hyperprolactinemia.
    Brain research, 1984, Dec-24, Volume: 324, Issue:2

    Topics: Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Domperidone; Dopamine; Female; Hypothalamus; Median Eminence; Naloxone; Nomifensine; Prolactin; Rats; Rats, Inbred Strains; Synaptic Transmission

1984
Evidence for an increased opioid inhibition of LH secretion in hyperprolactinaemic ovariectomized rats.
    The Journal of endocrinology, 1984, Volume: 101, Issue:1

    Topics: Animals; Castration; Depression, Chemical; Domperidone; Estradiol; Feedback; Female; Luteinizing Hormone; Naloxone; Pituitary Gland; Progesterone; Prolactin; Rats; Rats, Inbred Strains; Secretory Rate

1984
Dexamethasone: a potent blocker for radiation-induced taste aversion in rats.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:2

    Topics: Animals; Aspirin; Avoidance Learning; Cimetidine; Conditioning, Classical; Dexamethasone; Dimethyl Sulfoxide; Domperidone; Dose-Response Relationship, Radiation; Gamma Rays; Haloperidol; Insulin; Male; Naloxone; Rats; Rats, Inbred Strains; Taste

1982
Studies on the responses of plasma renin activity and aldosterone and cortisol levels to dopaminergic and opiate stimuli in man.
    Clinical endocrinology, 1981, Volume: 15, Issue:1

    Topics: Adult; Aldosterone; Carbidopa; Domperidone; Dopamine; Female; Humans; Hydrocortisone; Levodopa; Male; Naloxone; Posture; Renin

1981
Dopamine partially mediates the cardiovascular effects of naloxone after spinal injury.
    Brain research, 1981, Jun-01, Volume: 213, Issue:2

    Topics: Animals; Benzimidazoles; Blood Pressure; Cats; Domperidone; Dopamine; Female; Myocardial Contraction; Naloxone; Norepinephrine; Piperidines; Spinal Injuries

1981
Modification of naloxone-induced withdrawal signs by dextromethorphan in morphine-dependent mice.
    European journal of pharmacology, 1999, Jul-14, Volume: 377, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Benzazepines; Dextromethorphan; Domperidone; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Grooming; Male; Mice; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Pain; Substance Withdrawal Syndrome; Sulpiride

1999
Opioid mediated anti-nociceptive effect of domperidone and cisapride in mice.
    Acta pharmacologica Sinica, 2002, Volume: 23, Issue:1

    Topics: Analgesics, Non-Narcotic; Animals; Cisapride; Domperidone; Male; Mice; Naloxone; Nociceptors; Receptors, Opioid

2002
Formalin assay parameters differ in confirming the antinociceptive mechanism of domperidone in mice.
    Indian journal of experimental biology, 2004, Volume: 42, Issue:4

    Topics: Analgesics; Animals; Disinfectants; Domperidone; Dopamine Antagonists; Drug Combinations; Formaldehyde; Male; Mice; Naloxone; Narcotic Antagonists; Nociceptors; Pain; Pain Measurement; Time Factors

2004
Species-specific effects on hemolymph glucose control by serotonin, dopamine, and L-enkephalin and their inhibitors in Squilla mantis and Astacus leptodactylus (crustacea).
    Journal of experimental zoology. Part A, Comparative experimental biology, 2004, Sep-01, Volume: 301, Issue:9

    Topics: Analysis of Variance; Animals; Blood Glucose; Decapoda; Domperidone; Dopamine; Dopamine Antagonists; Enkephalins; Hemolymph; Naloxone; Serotonin; Serotonin Antagonists; Species Specificity

2004
Metformin inhibits visceral allodynia and increased gut permeability induced by stress in rats.
    Journal of gastroenterology and hepatology, 2019, Volume: 34, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Colon; Disease Models, Animal; Domperidone; Dopamine Antagonists; Evans Blue; Hyperalgesia; Hypoglycemic Agents; Intestinal Mucosa; Irritable Bowel Syndrome; Lipopolysaccharides; Male; Metformin; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nociception; Permeability; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; Stress, Physiological; Sulpiride

2019
Rotigotine-loaded microspheres exerts the antinociceptive effect via central dopaminergic system.
    European journal of pharmacology, 2021, Nov-05, Volume: 910

    Topics: Analgesics; Animals; Carrageenan; Corpus Striatum; Disease Models, Animal; Domperidone; Dopamine; Dopamine Agents; Dopamine D2 Receptor Antagonists; Inflammation; Injections; Male; Microspheres; Naloxone; Narcotic Antagonists; Pain; Periaqueductal Gray; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Stress, Mechanical; Temperature; Tetrahydronaphthalenes; Thiophenes

2021