domperidone and loperamide

domperidone has been researched along with loperamide in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's3 (27.27)18.2507
2000's3 (27.27)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mol, CA; Schinkel, AH; van Deemter, L; Wagenaar, E1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Andrews, PL; Bhandari, P; Bingham, S1
Cann, PA1
Maas, CL; van Duin, CT; van Miert, AS1
Fischer, H; Gottschlich, R; Seelig, A1
Bohets, H; De Maesschalck, R; Nagels, L; Peeters, K; Vanhoutte, K1
Anneveld, B; Augustijns, P; Brouwers, J; Corsetti, M; Hens, B; Reppas, C; Symillides, M; Turner, DB; Vertzoni, M1
Badaoui, M; Dickson, CJ; Hornak, V; Kells, A; Molteni, C; Rosta, E1

Trials

1 trial(s) available for domperidone and loperamide

ArticleYear
Gastrointestinal transfer: in vivo evaluation and implementation in in vitro and in silico predictive tools.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Oct-15, Volume: 63

    Topics: Biological Transport; Computer Simulation; Domperidone; Female; Gastrointestinal Tract; Healthy Volunteers; Humans; Loperamide; Male; Paromomycin; Time Factors; Young Adult

2014

Other Studies

10 other study(ies) available for domperidone and loperamide

ArticleYear
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.
    The Journal of clinical investigation, 1996, Jun-01, Volume: 97, Issue:11

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Cell Line; Clozapine; Diffusion; Domperidone; Epithelium; Flunitrazepam; Haloperidol; Humans; Kidney; Kinetics; Loperamide; Male; Mice; Mice, Inbred Strains; Ondansetron; Phenytoin; Recombinant Proteins; Structure-Activity Relationship; Swine; Tissue Distribution; Transfection

1996
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
The neuropharmacology of loperamide-induced emesis in the ferret: the role of the area postrema, vagus, opiate and 5-HT3 receptors.
    Neuropharmacology, 1992, Volume: 31, Issue:8

    Topics: Animals; Behavior, Animal; Cerebral Ventricles; Domperidone; Female; Fenclonine; Ferrets; Loperamide; Male; Narcotic Antagonists; Receptors, Opioid; Receptors, Serotonin; Serotonin Antagonists; Vagotomy; Vagus Nerve; Vomiting

1992
An approach to the design of therapeutic trials in IBS.
    Scandinavian journal of gastroenterology. Supplement, 1987, Volume: 130

    Topics: Clinical Trials as Topic; Colonic Diseases, Functional; Domperidone; Dose-Response Relationship, Drug; Female; Humans; Loperamide; Male; Medical History Taking

1987
Loperamide: evidence for a centrally mediated opioid effect on rumen motility in conscious goats and sheep.
    Journal of veterinary pharmacology and therapeutics, 1986, Volume: 9, Issue:1

    Topics: Animals; Domperidone; Gastrointestinal Motility; Goats; Kinetics; Loperamide; Naltrexone; Narcotics; Piperidines; Rumen; Sheep

1986
Blood-brain barrier permeation: molecular parameters governing passive diffusion.
    The Journal of membrane biology, 1998, Oct-01, Volume: 165, Issue:3

    Topics: Air; Amiodarone; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Butyrophenones; Diffusion; Domperidone; Histamine H1 Antagonists; Humans; Kinetics; Loperamide; Micelles; Models, Biological; Piperidines; Surface Properties; Thermodynamics; Water

1998
In situ dissolution testing using potentiometric sensors.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2008, Aug-07, Volume: 34, Issue:4-5

    Topics: Chromatography, High Pressure Liquid; Cinnarizine; Domperidone; Electrodes; Equipment Design; Excipients; Fiber Optic Technology; Ketoconazole; Kinetics; Loperamide; Nephelometry and Turbidimetry; Osmolar Concentration; Potentiometry; Reproducibility of Results; Solubility; Technology, Pharmaceutical

2008
Calculating Kinetic Rates and Membrane Permeability from Biased Simulations.
    The journal of physical chemistry. B, 2018, 12-13, Volume: 122, Issue:49

    Topics: Cell Membrane Permeability; Chlorpromazine; Desipramine; Domperidone; Kinetics; Labetalol; Lipid Bilayers; Loperamide; Molecular Dynamics Simulation; Molecular Structure; Propranolol; Thermodynamics; Verapamil

2018