domperidone and itraconazole

domperidone has been researched along with itraconazole in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's6 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Imai, H; Imanaga, J; Kotegawa, T; Ohashi, K; Ohyama, T; Tsutsumi, K; Yoshizato, T1
Imai, H; Kotegawa, T; Nakano, S; Tsutsumi, K; Yoshizato, T1
Ravenstijn, P; Sensenhauser, C; Snoeys, J; Templeton, I1

Trials

3 trial(s) available for domperidone and itraconazole

ArticleYear
Itraconazole and domperidone: a placebo-controlled drug interaction study.
    European journal of clinical pharmacology, 2012, Volume: 68, Issue:9

    Topics: Administration, Oral; Adult; Affect; Antifungal Agents; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Brain; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Electroencephalography; Enzyme Inhibitors; Half-Life; Humans; Itraconazole; Japan; Linear Models; Male; Membrane Transport Modulators; Metabolic Clearance Rate; Prolactin; Self Report; Up-Regulation; Young Adult

2012
Determination of domperidone in human plasma using high performance liquid chromatography with fluorescence detection for clinical application.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014, Jun-15, Volume: 961

    Topics: Adult; Chromatography, High Pressure Liquid; Domperidone; Fluorescence; Humans; Itraconazole; Limit of Detection; Male; Reproducibility of Results; Solid Phase Extraction

2014
A physiologically based pharmacokinetic modeling approach to predict drug-drug interactions between domperidone and inhibitors of CYP3A4.
    Biopharmaceutics & drug disposition, 2016, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Caco-2 Cells; Computer Simulation; Cytochrome P-450 CYP3A Inhibitors; Domperidone; Dopamine Antagonists; Drug Interactions; Erythromycin; Female; Humans; Itraconazole; Ketoconazole; Male; Microsomes, Liver; Middle Aged; Models, Biological; Young Adult

2016

Other Studies

7 other study(ies) available for domperidone and itraconazole

ArticleYear
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016