domperidone and cocaine

domperidone has been researched along with cocaine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's1 (6.67)18.2507
2000's9 (60.00)29.6817
2010's4 (26.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sen, S; Sinha, N1
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Li, J; Rajamani, R; Reynolds, CH; Tounge, BA1
Nagashima, R; Nishikawa, T; Tobita, M1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Caron, G; Ermondi, G; Visentin, S1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Bellman, K; Knegtel, RM; Settimo, L1
Goldberg, LI; Kamien, JB; Woolverton, WL1
Higgins, GA; Varty, GB1
Briand, LA; Flagel, SB; Robinson, TE; Seeman, P1
Aymerich, MS; Barrera, C; Franco, R; Seeman, P1
Crawford, CA; Eaton, SE; McDougall, SA; Mohd-Yusof, A1

Other Studies

15 other study(ies) available for domperidone and cocaine

ArticleYear
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
    Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18

    Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
A two-state homology model of the hERG K+ channel: application to ligand binding.
    Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation

2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:5

    Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Pharmacological analysis of the apomorphine discriminative stimulus in rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Benzazepines; Cocaine; Conditioning, Operant; Dextroamphetamine; Discrimination Learning; Domperidone; Dose-Response Relationship, Drug; Female; Fluoxetine; Macaca mulatta; Male; Physostigmine; Piribedil; Quipazine; Sodium Chloride

1987
Dopamine agonist-induced hypothermia and disruption of prepulse inhibition: evidence for a role of D3 receptors?
    Behavioural pharmacology, 1998, Volume: 9, Issue:5-6

    Topics: Animals; Body Temperature; Cocaine; Domperidone; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Hypothermia; Male; Piperazines; Raclopride; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Reflex, Startle; Salicylamides; Serotonin Antagonists

1998
Cocaine self-administration produces a persistent increase in dopamine D2 High receptors.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2008, Volume: 18, Issue:8

    Topics: Animals; Behavior, Animal; Binding, Competitive; Cocaine; Corpus Striatum; Domperidone; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Rats; Rats, Wistar; Receptors, Dopamine D2; Self Administration; Tritium; Up-Regulation

2008
Cocaine self-administration markedly increases dopamine D2 receptor negative cooperativity for dopamine binding: A receptor dimer-based analysis.
    Synapse (New York, N.Y.), 2010, Volume: 64, Issue:7

    Topics: Animals; Cocaine; Corpus Striatum; Domperidone; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Models, Neurological; Receptors, Dopamine D2; Self Administration; Tritium

2010
Age-dependent changes in cocaine sensitivity across early ontogeny in male and female rats: possible role of dorsal striatal D2(High) receptors.
    Psychopharmacology, 2015, Volume: 232, Issue:13

    Topics: Age Factors; Animals; Animals, Newborn; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Male; Motor Activity; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2

2015