domperidone and atropine

domperidone has been researched along with atropine in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199017 (48.57)18.7374
1990's3 (8.57)18.2507
2000's9 (25.71)29.6817
2010's6 (17.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Berger, Z; Laugier, R1
Lang, IM; Marvig, J1
Hikasa, Y; Ogasawara, S; Takase, K1
Itoh, Z; Mizumoto, A1
Sanger, GJ1
Delcenserie, R; Devaux, MA; Sarles, H1
Böhmer, G; Gouzoulis, E; Löffelholz, K; Raach, M; Schmid, K1
Cabranes, JA; Casanueva, FF; Diaz, Y; Dieguez, C; Fernandez-Cruz, A; Scanlon, MF; Schally, AV; Szoke, B; Villanueva, L1
Kameyama, M; Nabatame, H; Sasa, M; Takaori, S1
Smith, G; Turner, DA; Vickers, A1
Schuurkes, JA; Van Nueten, JM1
Jancsó, G; Rózsa, Z; Varró, V1
Funakoshi, A; Ibayashi, H; Matsumoto, M; Nakano, I; Sekiya, K; Shinozaki, H1
Kaakkola, S; Laitinen, LA; Lehtosalo, J1
Brock-Utne, JG1
Betti, R; Casanueva, F; Cocchi, D; Motta, T; Müller, EE; Zanardi, P1
Grijalva, CV; Roland, BL1
Karasawa, A; Kishibayashi, N; Suzuki, M; Yokoyama, T1
Dolezal, V; Tucek, S1
Anic, T; Aralica, G; Bilic, I; Buljat, G; Ivankovic, D; Mikus, D; Mise, S; Perovic, D; Petek, M; Prkacin, I; Rotkvic, I; Rucman, R; Seiwerth, S; Separovic, J; Sikiric, P; Stancic-Rokotov, D; Zoricic, I1
Kato, S; Matsumoto, M; Miyazawa, T; Takeuchi, K1
Kim, DK; Kumar, GK; Prabhakar, NR1
Bao, YR; Chang, X; Li, TJ; Meng, XS; Wang, S; Yu, XM1

Trials

2 trial(s) available for domperidone and atropine

ArticleYear
Evaluation of the combined effects of atropine and domperidone on the lower oesophageal sphincter.
    European journal of anaesthesiology, 1985, Volume: 2, Issue:3

    Topics: Adult; Atropine; Domperidone; Esophagogastric Junction; Humans; Pneumonia, Aspiration; Pressure

1985
Domperidone antagonizes the relaxant effect atropine on the lower esophageal sphincter.
    Anesthesia and analgesia, 1980, Volume: 59, Issue:12

    Topics: Adult; Antiemetics; Atropine; Benzimidazoles; Domperidone; Esophagogastric Junction; Gastroesophageal Reflux; Humans; Muscle Contraction; Muscle Relaxation; Piperidines; Preanesthetic Medication; Pressure

1980

Other Studies

33 other study(ies) available for domperidone and atropine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Dopamine, noradrenaline and isoprenaline: secretory and electrophysiological effects in vitro on mouse pancreas.
    The Journal of physiology, 1986, Volume: 376

    Topics: Action Potentials; Amylases; Animals; Atropine; Bis-Trimethylammonium Compounds; Domperidone; Dopamine; Dose-Response Relationship, Drug; Ganglionic Blockers; In Vitro Techniques; Isoproterenol; Male; Mice; Norepinephrine; Pancreas; Stimulation, Chemical; Sympatholytics; Tetrodotoxin; Time Factors

1986
Functional localization of specific receptors mediating gastrointestinal motor correlates of vomiting.
    The American journal of physiology, 1989, Volume: 256, Issue:1 Pt 1

    Topics: Animals; Apomorphine; Atropine; Copper; Copper Sulfate; Digestive System; Dogs; Domperidone; Female; Gastrointestinal Motility; Haloperidol; Hexamethonium; Hexamethonium Compounds; Male; Muscle Contraction; Naloxone; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Serotonin; Serotonin Antagonists; Sincalide; Vomiting

1989
Evidence for the involvement of alpha 2-adrenoceptors in the emetic action of xylazine in cats.
    American journal of veterinary research, 1989, Volume: 50, Issue:8

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Cat Diseases; Cats; Chlorpromazine; Diphenhydramine; Domperidone; Female; Hydroxydopamines; Male; Naloxone; Oxidopamine; Propranolol; Random Allocation; Receptors, Adrenergic, alpha; Thiazines; Vomiting; Xylazine

1989
[Anti-cholinesterase activity of dopamine D2 receptor antagonist: its clinical significance].
    Nihon Heikatsukin Gakkai zasshi, 1989, Volume: 25, Issue:4

    Topics: Acetylcholine; Animals; Atropine; Cholinesterase Inhibitors; Cisapride; Dogs; Domperidone; Dopamine Agents; Gastrointestinal Motility; Neostigmine; Piperidines

1989
Effects of metoclopramide and domperidone on cholinergically mediated contractions of human isolated stomach muscle.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:9

    Topics: Acetylcholine; Atropine; Carbachol; Domperidone; Electric Stimulation; Humans; In Vitro Techniques; Metoclopramide; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Stomach

1985
Action of dopamine on the exocrine pancreatic secretion of the intact dog.
    British journal of pharmacology, 1986, Volume: 88, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Bicarbonates; Dogs; Domperidone; Dopamine; Dose-Response Relationship, Drug; Pancreas; Pancreatic Juice; Proteins; Time Factors

1986
Dopaminergic control of respiration as shown by effects of 4-aminopyridine.
    European journal of pharmacology, 1986, Jan-29, Volume: 120, Issue:3

    Topics: 4-Aminopyridine; Aminopyridines; Anesthesia; Animals; Atropine; Domperidone; Dopamine; Haloperidol; Hemodynamics; Neuromuscular Depolarizing Agents; Phrenic Nerve; Prazosin; Rabbits; Respiration; Salivation; Vagotomy

1986
Atropine blockade of growth hormone (GH)-releasing hormone-induced GH secretion in man is not exerted at pituitary level.
    The Journal of clinical endocrinology and metabolism, 1986, Volume: 62, Issue:1

    Topics: Acetylcholine; Adolescent; Adult; Animals; Atropine; Cattle; Domperidone; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Kinetics; Male; Physostigmine; Pituitary Gland; Reference Values; Thyrotropin; Thyrotropin-Releasing Hormone

1986
Muscarinic receptor-mediated inhibition of dopaminergic excitatory input to caudate neurons from the substantia nigra.
    Japanese journal of pharmacology, 1988, Volume: 46, Issue:4

    Topics: Animals; Atropine; Bicuculline; Carbachol; Caudate Nucleus; Domperidone; Drug Interactions; Electrodes; Glutamates; Iontophoresis; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Muscarinic; Substantia Nigra

1988
Domperidone improves myogenically transmitted antroduodenal coordination by blocking dopaminergic receptor sites.
    Scandinavian journal of gastroenterology. Supplement, 1984, Volume: 96

    Topics: Animals; Atropine; Domperidone; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Duodenum; Gastrointestinal Motility; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Pyloric Antrum; Tetrodotoxin

1984
Possible involvement of capsaicin-sensitive sensory nerves in the regulation of intestinal blood flow in the dog.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 326, Issue:4

    Topics: Animals; Atropine; Capsaicin; Dogs; Domperidone; Female; Hexamethonium Compounds; Intestines; Male; Mesenteric Arteries; Neurons, Afferent; Phentolamine; Propranolol; Regional Blood Flow; Vasodilation; Yohimbine

1984
Cholinergic independent dopaminergic regulation of motilin release in man.
    Gastroenterologia Japonica, 1983, Volume: 18, Issue:6

    Topics: Adult; Atropine; Domperidone; Dopamine; Gastrointestinal Hormones; Humans; Motilin; Pancreatic Polypeptide; Time Factors

1983
Changes in blood-brain barrier permeability to drugs in decompressed rats.
    Undersea biomedical research, 1982, Volume: 9, Issue:3

    Topics: Animals; Atropine; Atropine Derivatives; Blood-Brain Barrier; Catalepsy; Decompression Sickness; Domperidone; Haloperidol; Humans; Male; Permeability; Pharmaceutical Preparations; Rats; Rats, Inbred Strains

1982
A role for dopamine in growth hormone regulation in the dog.
    Endocrinology, 1981, Volume: 108, Issue:4

    Topics: Animals; Apomorphine; Atropine; Benzimidazoles; Dogs; Domperidone; Dopamine; Female; Growth Hormone; Haloperidol; Isoquinolines; Kinetics; Male; Nomifensine; Phentolamine; Pimozide; Piperidines

1981
Gastric mucosal erosions induced by lateral hypothalamic damage: neuronal and dopaminergic mechanisms.
    Brain research, 1993, Mar-05, Volume: 605, Issue:1

    Topics: Animals; Apomorphine; Atropine; Domperidone; Dopamine; Dopamine Agents; Dopamine Antagonists; Gastric Mucosa; Hypothalamic Area, Lateral; Kainic Acid; Male; Nerve Fibers; Neurons; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques; Substantia Nigra; Tegmentum Mesencephali

1993
Effect of KW-5092, novel gastroprokinetic agent, on the peristalsis in the isolated guinea pig ileum.
    Japanese journal of pharmacology, 1997, Volume: 74, Issue:1

    Topics: Animals; Atropine; Cholinesterase Inhibitors; Domperidone; Dopamine Antagonists; Guinea Pigs; Ileum; Imidazoles; In Vitro Techniques; Male; Muscarinic Antagonists; Neostigmine; Nitriles; Peristalsis

1997
Calcium channels involved in the inhibition of acetylcholine release by presynaptic muscarinic receptors in rat striatum.
    British journal of pharmacology, 1999, Volume: 127, Issue:7

    Topics: Acetylcholine; Animals; Atropine; Calcium Channel Blockers; Calcium Channels; Carbachol; Cholinesterase Inhibitors; Domperidone; Dopamine Antagonists; Haloperidol; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Neostriatum; omega-Agatoxin IVA; omega-Conotoxin GVIA; Paraoxon; Peptides; Rats; Receptors, Muscarinic; Receptors, Presynaptic; Spider Venoms

1999
Haloperidol-stomach lesions attenuation by pentadecapeptide BPC 157, omeprazole, bromocriptine, but not atropine, lansoprazole, pantoprazole, ranitidine, cimetidine and misoprostol in mice.
    Life sciences, 2001, Mar-09, Volume: 68, Issue:16

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Atropine; Benzimidazoles; Bromocriptine; Cimetidine; Disease Models, Animal; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Indomethacin; Lansoprazole; Male; Mice; Mice, Inbred Strains; Misoprostol; Omeprazole; Pantoprazole; Peptide Fragments; Proteins; Ranitidine; Stomach Diseases; Sulfoxides

2001
Dopamine-induced protection against indomethacin-evoked intestinal lesions in rats--role of anti-intestinal motility mediated by D2 receptors.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atropine; Domperidone; Dopamine; Dopamine Antagonists; Gastrointestinal Motility; Indomethacin; Intestinal Diseases; Intestine, Small; Male; Mucus; Muscarinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Sulpiride; Yohimbine

2003
Acetylcholine release from the carotid body by hypoxia: evidence for the involvement of autoinhibitory receptors.
    Journal of applied physiology (Bethesda, Md. : 1985), 2004, Volume: 96, Issue:1

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Carotid Body; Domperidone; Dopamine Antagonists; Homeostasis; Hypercapnia; Hypoxia; Male; Muscarinic Antagonists; Rabbits; Receptors, Dopamine; Receptors, Muscarinic; Synaptic Transmission

2004
Multicomponent, multitarget integrated adjustment - Metabolomics study of Qizhiweitong particles curing gastrointestinal motility disorders in mice induced by atropine.
    Journal of ethnopharmacology, 2016, Aug-02, Volume: 189

    Topics: Animals; Atropine; Benzamides; Biomarkers; Chromatography, High Pressure Liquid; Chromatography, Liquid; Disease Models, Animal; Domperidone; Drugs, Chinese Herbal; Gastrointestinal Agents; Gastrointestinal Diseases; Gastrointestinal Motility; Least-Squares Analysis; Male; Metabolomics; Mice, Inbred ICR; Molecular Targeted Therapy; Morpholines; Multivariate Analysis; Phytotherapy; Plants, Medicinal; Principal Component Analysis; Signal Transduction; Systems Biology; Tandem Mass Spectrometry

2016